Garcinia Indica Choisy

Total Page：16

File Type：pdf, Size：1020Kb

Garcinia indica choisy The kokum fruit is cooling, antiseptic, purifies the blood and fights cholesterol. Garcinia indica seed also contains oil, which remains solid at room temperature and is used in food pharmaceutical and in cosmetics. It has medicinal uses both as a digestive tonic, and to fight paralysis.It is shown to improve the paralysed status of an individual. The HPLC [high pressure/performance liquid chromatography] analysis of Garcinia indica fruit shows major phytochemical hydroxy citric acid [HCA] which is claimed to have fat-reducing properties for the human body. Hydroxy citric acid is mainly found in the rind of the fruit. It is shown that HCA can inhibit the enzyme, citrate lyase which is needed for conversion of carbohydrates into fats. The fruit also shows presence of anthocyanins which are pigmented flavonoids. They are water soluble and help in scavenging free radicals. Flavonoids are known for their antioxidant activity, although it is research is going on in this field. Flavonoids are also referred to as bioflavonoid, since all flavonoids are biological in origin. They would be of great importance to athletes as heavy exercises generate large amount of free radicalsGarcinia indica choisy is a slender evergreen tree. The tree is also ornamental, with a dense canopy of green leaves and red-tinged tender emerging leaves. The tree is found in the tropical rain forests of Western Ghats, from kokan to mysore.The kokum fruit is cooling, antiseptic, purifies the blood and fights cholesterol. Garcinia indica seed also contains oil, which remains solid at room temperature and is used in food pharmaceutical and in cosmetics. Kokum fruit has lots of medicinal properties. It does not require irrigation, spraying or fertilizers. The tree doesnt require rainfall, doesn’t have any pest or diseases apart from the monkey menace, and is almost a crop which requires negligible attention. A paper presented at the Goa seminar (March 2005) suggests that the Garcinia indica has medicinal uses both as a digestive tonic, and to fight paralysis. It is shown to improve the paralysed status of an individual. About half to one glass of curry is prepared from the fruits, with a little salt and sugar, to be taken after meals. For paralysis, the clean-chopped stem bark is finely powdered and is added to boiling water. After 3-5 minutes, a lightly cooled decoction is used for washing the affected parts, two to three times a day. The HPLC [high pressure/performance liquid chromatography] analysis of Garcinia indica fruit shows major phytochemical hydroxy citric acid [HCA] which is claimed to have fat-reducing properties for the human body.Hydroxy citric acid is mainly found in the rind of the fruit. It is shown that HCA can inhibit the enzyme, citrate lyase which is needed for conversion of carbohydrates into fats. The fruit also shows presence of anthocyanins which are pigmented flavonoids.They are water soluble and help in scavenging free radicals.Flavonoids are known for their antioxidant activity, although it is research is going on in this field. Flavonoids are also referred to as bioflavonoid, since all flavonoids are biological in origin. They would be of great importance to athletes as heavy exercises generate large amount of free radicals. Lyonia, Volume #, Pages [ # - # ],.

Copy Link

Recommended publications

Tamarind 1990 - 2004
Tamarind 1990 - 2004 Author A. K. A. Dandjouma, C. Tchiegang, C. Kapseu and R. Ndjouenkeu Title Ricinodendron heudelotii (Bail.) Pierre ex Pax seeds treatments influence on the q Year 2004 Source title Rivista Italiana delle Sostanze Grasse Reference 81(5): 299-303 Abstract The effects of heating Ricinodendron heudelotii seeds on the quality of the oil extracted was studied. The seeds were preheated by dry and wet methods at three temperatures (50, 70 and 90 degrees C) for 10, 20, 30 and 60 minutes. The oil was extracted using the Soxhlet method with hexane. The results showed a significant change in oil acid value when heated at 90 degrees C for 60 minutes, with values of 2.76+or-0.18 for the dry method and 2.90+or-0.14 for the wet method. Heating at the same conditions yielded peroxide values of 10.70+or-0.03 for the dry method and 11.95+or-0.08 for the wet method. Author A. L. Khandare, U. Kumar P, R. G. Shanker, K. Venkaiah and N. Lakshmaiah Title Additional beneficial effect of tamarind ingestion over defluoridated water supply Year 2004 Source title Nutrition Reference 20(5): 433-436 Abstract Objective: We evaluated the effect of tamarind (Tamarindus indicus) on ingestion and whether it provides additional beneficial effects on mobilization of fluoride from the bone after children are provided defluoridated water. Methods: A randomized, diet control study was conducted in 30 subjects from a fluoride endemic area after significantly decreasing urinary fluoride excretion by supplying defluoridated water for 2 wk.
[Show full text]
Prioritization of Medicinal Plant for Their Development
PRIORITIZATION OF MEDICINAL PLANT FOR THEIR DEVELOPMENT Criteria for prioritization The National Medicinal Plant Board initially prioritized 32 medicinal plants at national level for their conservation and development. Recently, the list has been revised and 82 species have been included in the list. For the overall development of the medicinal plant sector in the state, there is a need to prioritize various medicinal plant species. This prioritization has to be based on different criteria such as ,(i) criteria for economic development, (ii) Prioritization to address the primary health care of the local community, (iii) medicinal plants prioritized for home and institutional garden, and (iv) prioritization of medicinal plants with conservation value. In the following section we have tried to touch upon different priorities relevant to the state. Medicinal Plants prioritized for trade for high income. The most important criterion they needs to be considered while prioritizing the species for high income is that the plants should be suitable to grow in the prevalent agroclimatic conditions of the state. The species should have high trade value. It should have consistently high demand. The collection, harvest and post harvest technology should suit to the site conditions of Meghalaya.There should have easy access to planting material and it should be comparatively easy to grow. Preference will also be given to those species which are suitable to grow in multi-tier plantations. The selected species should not get easily deteriorated on storage and continued cultivation. They should have enhanced scope for value addition either through primary processing or through secondary processing. A list of top ten prioritized species for obtaining high income through cultivation and trade is given in Table 18.
[Show full text]
Herbs, Spices and Essential Oils
Printed in Austria V.05-91153—March 2006—300 Herbs, spices and essential oils Post-harvest operations in developing countries UNITED NATIONS INDUSTRIAL DEVELOPMENT ORGANIZATION Vienna International Centre, P.O. Box 300, 1400 Vienna, Austria Telephone: (+43-1) 26026-0, Fax: (+43-1) 26926-69 UNITED NATIONS FOOD AND AGRICULTURE E-mail: unido@unido.org, Internet: http://www.unido.org INDUSTRIAL DEVELOPMENT ORGANIZATION OF THE ORGANIZATION UNITED NATIONS © UNIDO and FAO 2005 — First published 2005 All rights reserved. Reproduction and dissemination of material in this information product for educational or other non-commercial purposes are authorized without any prior written permission from the copyright holders provided the source is fully acknowledged. Reproduction of material in this information product for resale or other commercial purposes is prohibited without written permission of the copyright holders. Applications for such permission should be addressed to: - the Director, Agro-Industries and Sectoral Support Branch, UNIDO, Vienna International Centre, P.O. Box 300, 1400 Vienna, Austria or by e-mail to unido@unido.org - the Chief, Publishing Management Service, Information Division, FAO, Viale delle Terme di Caracalla, 00100 Rome, Italy or by e-mail to copyright@fao.org The designations employed and the presentation of material in this information product do not imply the expression of any opinion whatsoever on the part of the United Nations Industrial Development Organization or of the Food and Agriculture Organization of the United Nations concerning the legal or development status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.
[Show full text]
Research Article KOKUM (GARCINIA INDICA) - ITS STATUS, PROBLEMS and PROSPECTS of CULTIVATION and PROCESSING
International Journal of Agriculture Sciences ISSN: 0975-3710 & E-ISSN: 0975-9107, Volume 11, Issue 7, 2019, pp.-8239-8241. Available online at https://www.bioinfopublication.org/jouarchive.php?opt=&jouid=BPJ0000217 Research Article KOKUM (GARCINIA INDICA) - ITS STATUS, PROBLEMS AND PROSPECTS OF CULTIVATION AND PROCESSING LAXMINARAYAN HEGDE* Horticultural Research and Extension Centre, Sirsi, Uttara Kannada, 581401, University of Horticultural Sciences, Bagalkot, 587104, Karnataka, India *Corresponding Author: Email - hegdelax@gmail.com, hrspepper@gmail.com Received: December 11, 2018; Revised: April 11, 2019; Accepted: April 12, 2019; Published: April 15, 2019 Abstract: The Kokum tree has great potential in commercial cultivation. This very useful and beautiful tree is ideal for planting in pa rks and gardens, roadsides and in the compounds of houses and public institutions. The organoleptic analysis results revealed that the carbonated kokum was tastier and highly refreshing than the normal kokum drink. Keywords: Kokum (Garcinia indica), Organoleptic analysis Citation: Laxminarayan Hegde (2019) Kokum (Garcinia indica)- Its Status, Problems and Prospects of Cultivation and Processing. International Journal of Agriculture Sciences, ISSN: 0975-3710 & E-ISSN: 0975-9107, Volume 11, Issue 7, pp.- 8239-8241. Copyright: Copyright©2019 Laxminarayan Hegde. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. Introduction G. indica Choisy (Syn. G. pupurea) is a beautiful evergreen tree popularly called heat by activating the process of thermogenesis [4]. It is found to be a potential ‘Kokum’, found in the Western Ghats, along the west coast of Konkan, Goa, dietary supplement for weight loss and appetite control.
[Show full text]
Kokum Fruit Bar Development Via Response Surface Methodology (RSM)
Pritam Bafna et al Int. Journal of Engineering Research and Applications www.ijera.com ISSN : 2248-9622, Vol. 4, Issue 2( Version 1), February 2014, pp.223-230 RESEARCH ARTICLE OPEN ACCESS Kokum Fruit Bar Development via Response Surface Methodology (RSM). Pritam Bafna*, Mrs. N. Manimehalai Fruit and Vegetable Laboratory, Department of Food and Process Engineering, SRM University, Kattankulathur, India Abstract A response surface methodology (RSM) was used for the determination of optimum ingredients level to prepare kokum fruit bar. Kokum pulp was extracted using water extraction method at temperature (24.97ºC) and time (30.42 min). The effects of ingredients levels on sensory parameters like texture, overall acceptability and calcium content of the prepared fruit bar were studied by employing a Box- Behnken Design (BBD). During the experimental trials the pulp quantity is kept fixed. The coefficient of determination R² for texture, overall acceptability and calcium content were 0.8298, 0.9239 and 0.9842 respectively. Analysis of variable (ANOVA) performed on the experimental values showed that sugar and milk powder were the most important factors that affected characteristics of the kokum fruit bar as it exerted a highly significant influence (p < 0.05) on all the dependent variables. Based on surface and contour plots, optimum ingredients level for formation of kokum fruit bar were pulp, sugar, milk powder; 50g, 40g and 9.39g respectively. Key words: Kokum, Fruit Bar, Response Surface Methodology, Box- Behnken Design, Calcium, Optimization I. Introduction digestive drinks. Both birindi saar and kokum kadi Garcinia indica Choisy belonging to the are supposed to be digestive and to relieve gastric family Guttiferae (in the mangosteen) is an problems.
[Show full text]
Dietary Supplements Compendium Volume 1
2015 Dietary Supplements Compendium DSC Volume 1 General Notices and Requirements USP–NF General Chapters USP–NF Dietary Supplement Monographs USP–NF Excipient Monographs FCC General Provisions FCC Monographs FCC Identity Standards FCC Appendices Reagents, Indicators, and Solutions Reference Tables DSC217M_DSCVol1_Title_2015-01_V3.indd 1 2/2/15 12:18 PM 2 Notice and Warning Concerning U.S. Patent or Trademark Rights The inclusion in the USP Dietary Supplements Compendium of a monograph on any dietary supplement in respect to which patent or trademark rights may exist shall not be deemed, and is not intended as, a grant of, or authority to exercise, any right or privilege protected by such patent or trademark. All such rights and privileges are vested in the patent or trademark owner, and no other person may exercise the same without express permission, authority, or license secured from such patent or trademark owner. Concerning Use of the USP Dietary Supplements Compendium Attention is called to the fact that USP Dietary Supplements Compendium text is fully copyrighted. Authors and others wishing to use portions of the text should request permission to do so from the Legal Department of the United States Pharmacopeial Convention. Copyright © 2015 The United States Pharmacopeial Convention ISBN: 978-1-936424-41-2 12601 Twinbrook Parkway, Rockville, MD 20852 All rights reserved. DSC Contents iii Contents USP Dietary Supplements Compendium Volume 1 Volume 2 Members . v. Preface . v Mission and Preface . 1 Dietary Supplements Admission Evaluations . 1. General Notices and Requirements . 9 USP Dietary Supplement Verification Program . .205 USP–NF General Chapters . 25 Dietary Supplements Regulatory USP–NF Dietary Supplement Monographs .
[Show full text]
Identification of Antibacterial Component from Extract of Garcinia Indica Fruit Rinds Using LC/MS/MS
PO-CON1317E Identification of antibacterial component from extract of Garcinia indica fruit rinds using LC/MS/MS ASMS 2013 MP34-689 Shailendra Rane1, Shailesh Damale1, Shruti Raju1, Rashi Kochhar1, Deepti Bhandarkar1, Ajit Datar1, Jitendra Kelkar1, Pratap Rasam1, Manasi Kher2, Komal Barbade2 1Shimadzu Analytical (India) Pvt.Ltd., 1 A/B Rushabh Chambers, Makwana Road, Marol, Andheri (E), Mumbai-400059, Maharashtra, India. 2Guru Nanak Institute of Research and Development, G. N. Khalsa College, Matunga, Mumbai-400019, Maharashtra, India. Identification of antibacterial component from extract of Garcinia indica fruit rinds using LC/MS/MS 1. Introduction Medicinal plants have played an important role in drug compounds is still relevant because of continuous discovery with many pharmaceutical products originating development of resistance of bacteria to antibiotics. from plant. Isolation and characterization of antibacterial 1-1. Garcinia indica Garcinia indica, a plant from the mangosteen family western coast of the country. Fruits of Garcinia indica have (Clusiaceae), commonly known as ‘Kokum’ is used for been suggested in the Indian system of medicine for a culinary purposes in India. Garcinia indica is indigenous to number of diseases as a remedial drug[1]. the Western Ghats region of India located along the Classification of Garcinia indica [1] Kingdom : Plantae Division : Mangoliophyta Class : Magnoliopsida Order : Malpighiales Family : Clusiaceae Subfamily: Clusioideae Tribe : Garcinieae Genus : Garcinia Species : indica Fig. 1 Garcinia indica 1-2. Garcinol CH3 compound which have been used to explain most of its observed biological activities. However, emerging evidence CH3 suggests that garcinol could be useful as an anti-cancer 3 CH3 CH H3C agent, and it is increasingly being realized that garcinol is a O OH H3C pleiotropic agent capable of modulating key regulatory cell O signaling.
[Show full text]
Medicinal Potential of Garcinia Species and Their Compounds
molecules Review Medicinal Potential of Garcinia Species and Their Compounds Bruna Larissa Spontoni do Espirito Santo 1, Lidiani Figueiredo Santana 1 , Wilson Hino Kato Junior 2, Felipe de Oliveira de Araújo 3, Danielle Bogo 1, Karine de Cássia Freitas 1,* , Rita de Cássia Avellaneda Guimarães 1, Priscila Aiko Hiane 1 , Arnildo Pott 4, Wander Fernando de Oliveira Filiú 5, Marcel Arakaki Asato 6, Patrícia de Oliveira Figueiredo 7 and Paulo Roberto Haidamus de Oliveira Bastos 1 1 Graduate Program in Health and Development in the Central-West Region of Brazil, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil; bruna.spontoni@gmail.com (B.L.S.d.E.S.); lidi_lfs@hotmail.com (L.F.S.); daniellebogo@hotmail.com (D.B.); rita.guimaraes@ufms.br (R.d.C.A.G.); priscila.hiane@ufms.br (P.A.H.); phaidamus43@gmail.com (P.R.H.d.O.B.) 2 Graduate of Pharmaceutical Sciences, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil; hinokato@gmail.com 3 Graduate of Electrical Engineering, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil; felipe@nexsolar.com.br 4 Laboratory of Botany, Institute of Biosciences, Federal University of Mato Grosso do Sul, 79070-900 Campo Grande, Brazil; arnildo.pott@gmail.com 5 Faculty of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul-UFMS, 79070-900 Campo Grande, Brazil; wander.ﬁliu@gmail.com 6 Medical School, Federal University of Mato Grosso do Sul, 79070-900 Campo Grande, Brazil; marcel_arakakiasato@hotmail.com 7 Laboratory PRONABio (Bioactive Natural Products)-Chemistry Institute, Federal University of Mato Grosso do Sul-UFMS, 79074-460 Campo Grande, Brazil; patricia.ﬁgueiredo@ufms.br * Correspondence: kcfreitas@gmail.com; Tel.: +55-67-3345-7416 Academic Editor: Derek J.
[Show full text]
Dictionary of Cultivated Plants and Their Regions of Diversity Second Edition Revised Of: A.C
Dictionary of cultivated plants and their regions of diversity Second edition revised of: A.C. Zeven and P.M. Zhukovsky, 1975, Dictionary of cultivated plants and their centres of diversity 'N -'\:K 1~ Li Dictionary of cultivated plants and their regions of diversity Excluding most ornamentals, forest trees and lower plants A.C. Zeven andJ.M.J, de Wet K pudoc Centre for Agricultural Publishing and Documentation Wageningen - 1982 ~T—^/-/- /+<>?- •/ CIP-GEGEVENS Zeven, A.C. Dictionary ofcultivate d plants andthei rregion so f diversity: excluding mostornamentals ,fores t treesan d lowerplant s/ A.C .Zeve n andJ.M.J ,d eWet .- Wageninge n : Pudoc. -11 1 Herz,uitg . van:Dictionar y of cultivatedplant s andthei r centreso fdiversit y /A.C .Zeve n andP.M . Zhukovsky, 1975.- Me t index,lit .opg . ISBN 90-220-0785-5 SISO63 2UD C63 3 Trefw.:plantenteelt . ISBN 90-220-0785-5 ©Centre forAgricultura l Publishing and Documentation, Wageningen,1982 . Nopar t of thisboo k mayb e reproduced andpublishe d in any form,b y print, photoprint,microfil m or any othermean swithou t written permission from thepublisher . Contents Preface 7 History of thewor k 8 Origins of agriculture anddomesticatio n ofplant s Cradles of agriculture and regions of diversity 21 1 Chinese-Japanese Region 32 2 Indochinese-IndonesianRegio n 48 3 Australian Region 65 4 Hindustani Region 70 5 Central AsianRegio n 81 6 NearEaster n Region 87 7 Mediterranean Region 103 8 African Region 121 9 European-Siberian Region 148 10 South American Region 164 11 CentralAmerica n andMexica n Region 185 12 NorthAmerica n Region 199 Specieswithou t an identified region 207 References 209 Indexo fbotanica l names 228 Preface The aimo f thiswor k ist ogiv e thereade r quick reference toth e regionso f diversity ofcultivate d plants.Fo r important crops,region so fdiversit y of related wild species areals opresented .Wil d species areofte nusefu l sources of genes to improve thevalu eo fcrops .
[Show full text]
Nutrient Properties of Important Garcinia Fruits of India
Diversity of Garcinia species in the Western Ghats: Phytochemical Perspective JNTBGRI Chapter 12 Nutrient properties of important Garcinia fruits of India Utpala Parthasarathy* and O. P. Nandakishore ICAR- Indian Institute of Spices Research Kozhikode- 673012, Kerala, India * Corresponding author Abstract The importance of natural products is increasing day by day as the safety of synthetic alternatives has generated lots of controversial questions. Garcinia species are an important group of plants, being used for different purposes, especially as fruit crops, source of edible oils and fats, and nutraceuticals in different parts of the world. The nutraceutical property of a fruit is determined by the metabolites like carbohydrates, proteins, vitamins and minerals and also the secondary metabolites such as phenols and flavonoids. The food and nutritive values of Garcinia species have attracted significant scientific attention and the present chapter is an attempt to review the nutrient properties of important Garcinia fruits in India. Keywords: Garcinia fruits, Nutrient properties, Minerals, Vitamins, Phenolics Introduction Plants and fruits are nature’s wonderful gift to mankind; indeed, the edible fruits are life enhancing medicines packed with vitamins, minerals, antioxidants and many phyto-nutrients. They are an absolute feast to our sight, not just because of their color and flavor but for their unique nutrition profile that help to keep human body healthy. There are plenty of underutilized fruit crops which possess immense nutraceutical value. The underutilized species are restricted to the geographical place of their availability but not explored properly for their constitution or utility (Gruere et al., 2006). Majority of them produce fruits which are rich sources of carbohydrates, proteins, fats, vitamins and minerals than the conventional fruits (Krishnamurthy and Sarala, 2011).
[Show full text]
Isolation and Characterization of Natural
ABSTRACT OF THE DISSERTATION ISOLATION AND CHARACTERIZATION OF NATURAL PRODUCTS FROM GINGER AND ALLIUM URSINUM BY HOU WU Dissertation Director: Dr. Chi-Tang Ho Phenolic compounds from natural sources are receiving increasing attention recent years since they were reported to have a remarkable spectrum of biological activities including antioxidant, anti-inflammatory and anti-carcinogenic activities. They may have many health benefits and can be considered possible chemo- preventive agents against cancer. In this research, we attempted to isolate and characterize phenolic compounds from two food sources: ginger and Allium ursinum. Solvent extraction and a series of column chromatography methods were used for isolation of compounds, while structures were elucidated by integration of data from MS, 1H-NMR, 13C-NMR, HMBC and HMQC. Antioxidant activities were evaluated by DPPH method and anti- inflammatory activities were assessed by nitric oxide production model. Ginger is one of most widely used spices. It has a long history of medicinal use dating back 2500 years. Although there have been many reports concerning ii chemical constituents and some biological activities of ginger, most works used ginger extracts or focused on gingerols to study the biological activities of ginger. We suggest that the bioactivities of shogaols are also very important since shogaols are more stable than gingerols and a considerable amount of gingerols will be converted to shogaols in ginger products. In present work, eight phenolic compounds were isolated and identified from ginger extract. They included 6-gingerol, 8-gingerol, 10- gingerol, 6-shogaol, 8—shogaols, 10-shogaol, 6-paradol and 1-dehydro-6-gingerdione. DPPH study showed that 6-shogaol had a comparable antioxidant activity compared with 6-gingerol, the 50% DPPH scavenge concentrations of both compounds were 21 µM.
[Show full text]
Anti-Obesity Effects of Garcinia Indica High Pressure Ethanolic Extract in Vitro
International Journal of Herbal Medicine 2021; 9(3): 01-08 E-ISSN: 2321-2187 P-ISSN: 2394-0514 Anti-obesity effects of Garcinia indica high pressure www.florajournal.com IJHM 2021; 9(3): 01-08 ethanolic extract in vitro Received: 02-02-2020 Accepted: 05-03-2020 Cheppail Ramachandran, Karl-Werner Quirin, Anja Cawelius, Enrique Cheppail Ramachandran Senior Research Scientist and Escalon and Steven J Melnick Chief Science Officer, Department of Pathology, Abstract Nicklaus Children’s Hospital, Obesity is one of the most common metabolic diseases that often lead to cardiovascular diseases, type II 3100 SW 62nd Avenue, Miami, FL 33155, United States diabetes, cancer, and osteoarthritis. Inhibition of adipogenesis is a therapeutic target for reducing obesity and obesity-related disorders. We have investigated the anti-adipogenic effect of a supercritical ethanolic Karl-Werner Quirin extract of dried fruits of Garcinia indica in-vitro. Chemical analysis of the high pressure ethanolic (HPE) Flavex Naturextrakte, extract showed that it has 36.7% hydroxy citric acid (HCA), 2.5% garcinol, 1.5% xanthochymol, 0.38% Rehlingen, Germany isogarcinol, and trace amounts of α-mangostin and cyaanidin-3-0-glucoside. G. indica HPE extract has an IC50 values of 112 ug/ml in 3T3-L1 pre-adipocytes and 140 ug/ml in differentiated adipocytes in the Anja Cawelius cytotoxicity assays. The HPE extract inhibited the adipocyte differentiation significantly in a dose- Flavex Naturextrakte, dependent manner with increasing concentrations of extract in 3T3-L1 preadipocytes. Treatment of Rehlingen, Germany HepG2 liver cells with G. indica HPE extract down regulated mRNA expression of mTOR, GLUT3 and HIF-1α genes and up regulated AMPKα genes very significantly.
[Show full text]