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Epidemiology of Rabies
How to cite: Putra, K. S. A. (2018). Epidemiology of rabies. International Journal of Chemical & Material Sciences, 1(1), 14-24. https://doi.org/10.31295/ijcms.v1n1.4 Epidemiology of Rabies Ketut Santhia Adhy Putra Independent Research of Zoonotic Diseases Ex. coordinator of Virology Laboratory, BBVet Denpasar, Directorate General of Livestock and Animal Health, Ministry of Agriculture, Jakarta [email protected] / [email protected] Abstract The occurrence of an outbreak of rabies in Bali as a shock to the people and local governments are instantly becoming the world's attention because of Bali as a world tourism destination. Since the first outbreak in the southern peninsula of Bali in November 2008, rabies quickly spread across the districts/municipality, until July 2015 had spread across 54 subdistricts and 263 villages. The proportion of rabies cases in the subdistricts and villages the highest occurred in 2011 is shown 94.7% and 36.7%, respectively, but its spread dropped dramatically in 2013 only occurred in 23 subdistricts (40.4%) and 38 villages (4,2%), though rabies outbreak back by increasing the number and distribution of rabies cases significantly in 2014, spread over 94 villages even until July 2015 spread over 89 villages. Rabies attacks the various breeds of dogs with the proportion of rabies in the local dogs showed the highest (98.44%), as well as the male dog, is very significantly higher than female dogs. By age group, the proportion seen in the age group of 1 to 2 years showed the highest (39.9%). Other animals, such as cats, cows, goats, and pigs have also contracted the rabies infected dog bitesthe. -
The Creation of Neuroscience
The Creation of Neuroscience The Society for Neuroscience and the Quest for Disciplinary Unity 1969-1995 Introduction rom the molecular biology of a single neuron to the breathtakingly complex circuitry of the entire human nervous system, our understanding of the brain and how it works has undergone radical F changes over the past century. These advances have brought us tantalizingly closer to genu- inely mechanistic and scientifically rigorous explanations of how the brain’s roughly 100 billion neurons, interacting through trillions of synaptic connections, function both as single units and as larger ensem- bles. The professional field of neuroscience, in keeping pace with these important scientific develop- ments, has dramatically reshaped the organization of biological sciences across the globe over the last 50 years. Much like physics during its dominant era in the 1950s and 1960s, neuroscience has become the leading scientific discipline with regard to funding, numbers of scientists, and numbers of trainees. Furthermore, neuroscience as fact, explanation, and myth has just as dramatically redrawn our cultural landscape and redefined how Western popular culture understands who we are as individuals. In the 1950s, especially in the United States, Freud and his successors stood at the center of all cultural expla- nations for psychological suffering. In the new millennium, we perceive such suffering as erupting no longer from a repressed unconscious but, instead, from a pathophysiology rooted in and caused by brain abnormalities and dysfunctions. Indeed, the normal as well as the pathological have become thoroughly neurobiological in the last several decades. In the process, entirely new vistas have opened up in fields ranging from neuroeconomics and neurophilosophy to consumer products, as exemplified by an entire line of soft drinks advertised as offering “neuro” benefits. -
Vpublic HEALTH REPORTS .V .OL~35 NOVEMBER 12, 1920 No
vPUBLIC HEALTH REPORTS .V .OL~35 NOVEMBER 12, 1920 No. 46 A STUDY OF THE RELATION OF FAMILY INCOME AND OTHER ECONOMIC FACTORS TO PELLAGRA INCIDENCE IN SEVEN COTTON-MILL VILLAGES OF SOUTH CAROLINA IN 1916.1 By JOSEPH GOLDBERGER, Surgeon; G. A. WHzzLER, Passed Assistant Surgeon; and EDGAR SYDEI- STRICKEE, Statistician, United States Public Health Service. CONTENT& I. Review of literature. III. Fellagra incidence according to eco- II. Plan aid methods of present study. nomic status. Locality. Discussion. Population. (a) Bad hygiene and sanita- Pellagra incidence. tion. Season. (b) Difference in age and Dietary data. sex composition. Data relating to economic condi- (c) Differences in diet. tions. Differences in incidence Family income. among households. Availability of food supply. Differences in incidence Economic classification. among villages. Method of classification ac- IV. Discussion. cording to economic status. V. Summary and conclusions. Results of classification. VI. References. In the spring of 1916 we began a study of the relation of various factors to-pellagra incidence in certain representative textile-mill communiities of South Carolina. On a varying scale the study was continued through 1917 and 1918. The results of the first year's (1916) study with respect to diet,2 to age, sex, occupation, disabling sickness,3 and to sanitation4 have already been reported. At the present time we wish to record the results of the part of the study dealing with the relation of conditions of an economic nature to the incidence of the disease. L REVIEW OF LITERATURE. A close association of pellagra with poverty has been repeatedly remarked upon since the time of the first recognition of the disease. -
December 11, 2001, NIH Record, Vol. LIII, No. 25
R a Still The Second Best Thing About Payday Dyer Lecturer Probes Persistence H GHL I G •H -TS Post-Sept. 11 Strategies Debated Of Cellular Memory Current, Future Security Measures By Anne A . Oplinger Cellular memory, one of the immune NIH Presents Weighed at Town Meeting system's most astounding characteristics, Security Issues to Employees By Carla Garnett is the subject of the 50th R.E. Dyer lecture he adage "you can never please everyone" might wel~ have scheduled for Wednesday, Dec. 19. The been written to describe reaction to heightened security 0 lecture, lmmuno N IH Gains New measures taken and planned for NIH following the Sept. 11 logical Memory: Deputy Director T tragedy. That's according to an unofficial barometer of e~ployee Lessons for Vaccine remarks Nov. 19 at the first of fow: scheduled town meetmgs on Development.ff will "Safety and Security at the NIH." There was perhaps only one I #. be presented by Dr. NCI Reports on thing everyone could agree on: That is, NIH now conducts Rafi Ahmed at 3 p.m. Progress Against business differently than it did before Sept. 11. in Masur Audito Cancer "Tllis is an opportunity to fill you in on what's going on, the rium, Bldg. 10. -~~-~ · . 1 rationale for what's happening and to hear your ideas," said Dr. """' . ' .,_ Michael Gottesman NIH deputy director for intramural research, . -~ .... Anyone who has during opening rem;rks at the meeting held in Masu_r Auditorium. had chicken pox, Acknowledging that many employees have asked him what they Dr. Rafi Ahmed mumps, measles or can do to help NIH and the nation at a time like this, Gottesman certain other told the audience "What we do here already is of incredible childhood diseases will never have that importance to th~ country. -
Southern and Eastern African Rabies Group International Symposium
PROCEEDINGS OF, THE SOUTHERN AND EASTERN AFRICAN RABIES GROUP INTERNATIONAL SYMPOSIUM PIETERMARITZBURG, SOUTH AFRICA 29-30 APRIL 1993 PROCEEDINGS OF THE SOUTHERN AND EASTERN AFRICAN RABIES GROUP INTERNATIONAL SYMPOSIUM PIETERMARITZBURG, SOUTH AFRICA 29-30 APRIL 1993 PUBLISHED BY S.E.A.R.G. EDITED BY GEORGE C. BISHOP S.E.A.R.G. ALLERTON REGIONAL VETERINARY LABORATORY P/BAG X2 CASCADES SOUTH AFRICA 3202 - 3 - - 4 - CONTENTS FOREWORD.........................................................................................................................................6 ACKNOWLEDGEMENTS..................................................................................................................7 PROGRAMME .....................................................................................................................................9 OPENING ADDRESS.........................................................................................................................11 RABIES : THE HUMAN PERSPECTIVE KEY NOTE ADDRESS..............................................14 RABIES : THE INTERNATIONAL SITUATION..........................................................................16 RABIES IN SOUTHERN AFRICA...................................................................................................20 CANINE RABIES ...............................................................................................................................21 A PAEDIATRICIAN'S PERSPECTIVE OF RABIES....................................................................25 -
January 22, 2010, NIH Record, Vol. LXII, No. 2
JANUARY 22, 2010 The Second Best Thing About Payday VOL. LXII, NO. 2 King’s Lessons Are Not Past, but Present By Valerie Lambros ABOVE · The renovation of Bldg. 3 will retain ore than 40 years after the assassination of Dr. Martin Luther King, Jr., the some architectural features. See story country has surely come a long way. However, as the keynote speaker of the below. M NIH presentation to observe the civil rights leader’s birthday pointed out, there is features much work to be done. The NIH event celebrating King’s life and work was kicked off by a performance by 1 musicians from the Thelonious Monk Institute of Jazz and headlined by author and King’s Legacy Still Lives sociologist Dr. Michael Eric Dyson. 3 NIH director Dr. Francis Collins NHLBI Hosts Stem Cell Symposium opened the event by reflecting on 7 King’s message of service to others. NIH Recruits Management Interns Recalling a famous King quote, Collins said, “We all must decide whether we 12 will walk in the light of creative altru- Jackson Ends 62-Year NIH Career ism, or the darkness of destructive self- ishness.” Dr. Vivian Pinn, director of departments see king observance, page 6 Dr. Michael Eric Dyson gives the keynote lecture at NIH’s annual King celebration. Briefs 2 Digest 10 ‘Decommissioned’ Bldg. 3 Gets Ready to U.S.-India Research Collaboration Volunteers 11 Shine Again Addresses HIV, STDs By Valerie Lambros By David Taylor Facelifts aren’t common treatments at NIH. U.S. and Indian scientists gathered recent- Unless you’re talking about buildings. -
Preparedness for an Emerging Infectious Disease
pathogens Review Rabies in Our Neighbourhood: Preparedness for an Emerging Infectious Disease Michael P. Ward 1,* and Victoria J. Brookes 2,3 1 Sydney School of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia 2 School of Animal and Veterinary Sciences, Faculty of Science, Charles Sturt University, Wagga Wagga, NSW 2678, Australia; [email protected] 3 Graham Centre for Agricultural Innovation (NSW Department of Primary Industries and Charles Sturt University), Wagga Wagga, NSW 2678, Australia * Correspondence: [email protected]; Tel.: +61-293511607 Abstract: Emerging infectious disease (EID) events have the potential to cause devastating impacts on human, animal and environmental health. A range of tools exist which can be applied to address EID event detection, preparedness and response. Here we use a case study of rabies in Southeast Asia and Oceania to illustrate, via nearly a decade of research activities, how such tools can be systematically integrated into a framework for EID preparedness. During the past three decades, canine rabies has spread to previously free areas of Southeast Asia, threatening the rabies-free status of countries such as Timor Leste, Papua New Guinea and Australia. The program of research to address rabies preparedness in the Oceanic region has included scanning and surveillance to define the emerging nature of canine rabies within the Southeast Asia region; field studies to collect information on potential reservoir species, their distribution and behaviour; participatory and sociological studies to identify priorities for disease response; and targeted risk assessment and disease modelling studies. Lessons learnt include the need to develop methods to collect data in remote regions, and the need to Citation: Ward, M.P.; Brookes, V.J. -
Springer International Publishing AG, Part of Springer Nature 2018 1 M
Biomedicine and Its Historiography: A Systematic Review Nicolas Rasmussen Contents Introduction ....................................................................................... 1 What Is Biomedicine? ............................................................................ 2 Biomedicine’s Postwar Development ............................................................ 7 The Distribution of Activity in Biomedicine and in Its Historiography . ...................... 14 Conclusion ........................................................................................ 19 References ........................................................................................ 20 Abstract In this essay I conduct a quantitative systematic review of the scholarly literature in history of life sciences, assessing how well the distribution of the activity of historians aligns with the distribution of activities of scientists across fields of biomedical research as defined by expenditures by the cognate institutes of the United States NIH. I also ask how well the distribution of resources to the various research fields of biomedicine in the second half of the 20th Century has aligned with morbidity and mortality in the United States associated with the cognate disease categories. The two exercises point to underexplored areas for historical work, and open new historical questions about research policy in the US. Introduction I have taken an unusual approach in this essay to ask a question that, to my knowledge, has not been addressed before: how -
Eulogy for the Clinical Research Center
Eulogy for the clinical research center David G. Nathan, David M. Nathan J Clin Invest. 2016;126(7):2388-2391. https://doi.org/10.1172/JCI88381. Op-Ed The extramural General Clinical Research Center (GCRC) program has been funded for more than 50 years, first by the National Center for Research Resources, NIH, and more recently as part of the Clinical Translational Science Award (CTSA) program through the newly formed National Center for Advancing Translation Sciences (NCATS). The GCRCs represent the federally funded laboratories that employ a highly trained cadre of research nurses, dietitians, and other support staff and in which generations of clinical investigators trained and performed groundbreaking human studies that advanced medical science and improved clinical care. Without the opportunity for adequate discussion, NCATS has now stopped funding these Research Centers. In this “eulogy,” we review the origins and history of the GCRCs, their contributions to the advancement of medicine, and the recent events that have essentially defunded them. We mourn their loss. Find the latest version: https://jci.me/88381/pdf OP-ED The Journal of Clinical Investigation Eulogy for the clinical research center David G. Nathan1 and David M. Nathan2 1Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA. 2Diabetes Center and Clinical Research Center, Massachusetts General Hospital (MGH), Harvard Medical School, Boston, Massachusetts, USA. icans with a desire to learn the biomedical research technology of the early twentieth The extramural General Clinical Research Center (GCRC) program has been century were forced to travel to England, funded for more than 50 years, first by the National Center for Research France, Austria, or Germany. -
WHO Expert Consultation on Rabies, First Report
WHO Technical Report Series 931 WHO EXPERT CONSULTATION ON RABIES First Report 1 WHO Library Cataloguing-in-Publication Data WHO Expert Consultation on Rabies (2004 : Geneva, Switzerland) WHO Expert Consultation on Rabies : first report. (WHO technical report series ; 931) 1.Rabies - prevention and control 2.Rabies vaccines 3.Rabies virus 4.Epidemiologic surveillance 5.Guidelines I.Title II.Series. ISBN 92 4 120931 3 (NLM classification: WC 550) ISSN 0512-3054 © World Health Organization 2005 All rights reserved. Publications of the World Health Organization can be obtained from WHO Press, World Health Organization, 20 Avenue Appia, 1211 Geneva 27, Switzerland (tel: +41 22 791 2476; fax: +41 22 791 4857; email: [email protected]). Requests for permission to reproduce or translate WHO publications – whether for sale or for noncommercial distribution – should be addressed to WHO Press, at the above address (fax: +41 22 791 4806; email: [email protected]). The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the World Health Organization concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. Dotted lines on maps represent approximate border lines for which there may not yet be full agreement. The mention of specific companies or of certain manufacturers’ products does not imply that they are endorsed or recommended by the World Health Organization in preference to others of a similar nature that are not mentioned. Errors and omissions excepted, the names of proprietary products are distinguished by initial capital letters. -
The Forgotten Plague
AmericanHeritage.com / THE FORGOTTEN PLAGUE http://www.americanheritage.com/articles/magazine/ah/2000/8/... December 2000 Volume 51, Issue 8 THE FORGOTTEN PLAGUE A MURDEROUS DISEASE WAS RAVAGING THE SOUTH. THEN ONE BRAVE AND DETERMINED DOCTOR DISCOVERED THE CURE—AND NOBODY BELIEVED HIM. BY DANIEL AKST Oblivion is a virtue in a disease. Cancer, AIDS, diabetes, and even tuberculosis are too much with us, but hardly anyone knows what pellagra is because the disfiguring deadly illness is virtually nonexistent in America today. For the first third of this century, pellagra was a scourge across the American South, killing thousands and afflicting hundreds of thousands more. Its cause was unknown, and there was no treatment, let alone cure. Victims were shunned like lepers, and by 1914 the sickness was a national scandal. The conquest of pellagra was a triumph of epidemiology over an affliction perhaps as ancient as the Bible, but it was also a triumph of one remarkable man, a medical Sherlock Holmes who fought ignorance, politics, and injustice as well as the disease. Even when the mystery of this preventable killer was solved, pellagra raged for another generation. It was as if the disease mocked science as crucial but insufficient. Pellagra is no longer a national health threat, and that is exactly why the experience of its conqueror is worth retelling. Pellagra was known as the disease of the three D’s: dermatitis, diarrhea, and dementia. Victims suffered scaling, leprous skin, intestinal distress, lethargy, and depression. The trademark symptom was a butterfly rash—an ugly symmetrical blotch that spread across the victim’s face—marking him or her for all to see. -
Original Article RABIES in EUROPE in 2010-2019
Bulgarian Journal of Veterinary Medicine, 2020 ONLINE FIRST ISSN 1311-1477; DOI: 10.15547/bjvm.2020-0077 Original article RABIES IN EUROPE IN 20102019 M. FLIS Department of Animal Ethology and Wildlife Management, Faculty of Animal Sciences and Bioeconomy, University of Life Sciences in Lublin, Lublin, Poland Summary Flis, M., 2020. Rabies in Europe in 20102019. Bulg. J. Vet. Med. (online first). The paper presents the epizootic and epidemiological situation of rabies in European countries during the last decade. The presented results indicate that the oral immunisation of fox anti-rabies (ORV), used in many European countries, significantly reduced the number of rabies cases found in ground mammals, but did not eliminate the virus at all. Currently, the largest reservoir of the virus are Eastern European countries where there are no immunisation activities or their effectiveness is low. Due to the absence of geographical barriers, the virus reappears in countries that have been described as free from rabies. As a rule, it is dragged into these areas along with the movement of companion animals and by people travelling to countries where the prevalence of the virus is common. It should be emphasised that due to the significant elimination of the virus in wild and domestic animals, it found quite quickly found a new reservoir in a specific group of mammals, having the ability to fly, like bats. Currently there is no possibility of carrying out any preventive measures in bats, so all the virus strains found in this group of animals are dangerous to humans, raising possibilities of epidemiological threat.