Byung Gil Moon, et al. • Ocular Inflammation Associated with Systemic Infection HMR Review Ocular Inflammation Associated with Systemic Infection Hanyang Med Rev 2016;36:192-202 http://dx.doi.org/10.7599/hmr.2016.36.3.192 pISSN 1738-429X eISSN 2234-4446 Byung Gil Moon, Joo Yong Lee Department of Ophthalmology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Systemic infections that are caused by various types of pathogenic organisms can be spread Correspondence to: Joo Yong Lee Department of Ophthalmology, Asan to the eyes as well as to other solid organs. Bacteria, parasites, and viruses can invade the Medical Center, University of Ulsan eyes via the bloodstream. Despite advances in the diagnosis and treatment of systemic in- College of Medicine, 88 Olympic-ro fections, many patients still suffer from endogenous ocular infections; this is particularly 43-gil, Songpa-gu, Seoul 05505, Korea Tel: +82-2-3010-3976 due to an increase in the number of immunosuppressed patients such as those with hu- Fax: +82-2-470-6440 man immunodeficiency virus infection, those who have had organ transplantations, and E-mail:
[email protected] those being administered systemic chemotherapeutic and immunomodulating agents, which may increase the chance of ocular involvement. In this review, we clinically evalu- Received 2 July 2016 Revised 21 July 2016 ated posterior segment manifestations in the eye caused by hematogenous penetration Accepted 27 July 2016 of systemic infections. We focused on the conditions that ophthalmologists encounter This is an Open Access article distributed under most often and that require cooperation with other medical specialists.