Authors: Pallavi Subhraveti Ron Caspi Quang Ong Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_900114625Cyc: Granulicella pectinivorans DSM 21001 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari

RS09495 TatC RS09750 RS20295 RS11150 RS20770 RS15280 RS02785 oxidase RS08985 BamA RS09255 RS12435 RS03905 RS00870 RS13555 RS18200 RS07085 RS19100 RS00070 RS01665 RS14660 RS12200 RS03375 RS03870 RS00400 RS03940 RS16255 RS20310 RS10995 RS05120 RS00010 RS06305 RS21230 CobD RS12860 RS20510 RS06930 RS08700 RS15340 RS12015 RS18325 RS13525 RS14895 RS04960 RS03050 RS17765 RS01810 RS04340 RS17250 RS16375 RS06185 RS17685 RS20760 RS00410 RS16790 RS08855 RS17770 RS10545 RS21355 RS14235 RS16885 RS13005 RS09775 RS07480 RS00935 RS10145 RS03525 RS10670 RS07775 RS04805 RS02950 RS12690 RS07665 RS07280 RS09575 RS14245 RS07805 RS01545 RS05455 RS18705 RS20755 RS02925 RS09145 RS01890 RS10335 RS12785 RS05415 RS13125 RS07855 RS05190 RS08695 RS19540 RS19675 RS12895 RS20735 RS12145 RS21125 RS12445 RS18260 RS01510 RS00175 RS11805 RS20205 RS11450 RS05410 RS00965 RS17530 RS05500 RS14625 RS08970 RS06220

RS04745 RS15725

RS15545 RS02470

RS05125 RS04090 Macromolecule Modification RS16830 Cofactor, Prosthetic Group, Electron Carrier, and Vitamin Biosynthesis Other Biosynthesis γ D-glycero-D- 38- a 1-acyl-sn tRNA processing undecaprenyl- L-alanyl- -D- α β DNA combined a uridine dCDP [2Fe-2S] iron-sulfur cluster biosynthesis Nucleoside and Nucleotide Degradation a purine a 2,3,4-saturated a 2,3,4-saturated 2- an L-rhamnoside D-glycero- -D- DMKH a [protein] Ser/Thr acetyl-CoA H O superpathway of thiamine diphosphate biosynthesis I heme b biosynthesis thiamine diphosphate Aminoacyl-tRNA Charging C1 Compound Utilization and Assimilation diphospho-N- UDP-N-acetyl- glutamyl-meso-2,6- with exogenous manno-heptose 2 40 in tRNA ser 2 2 -glycerol 3- FlgK RS13465 cob(II)yrinate a,c-diamide thiamine salvage II L-dopa and L- ribonucleoside adenosylcobinamide fatty acyl-[acp] lysophosphatidate alpha-L- manno-heptose ATP ribonucleotide- dGDP molybdenum cofactor biosynthesis acetylmuramoyl- UDP-N-acetyl- α-D-muramate diaminopimeloyl- DNA to form a 7-phosphate bifunctional serine/threonine tRNA acetyl-CoA hydrogenase phosphate I (aerobic) biosynthesis II (Bacillus) dopachrome 1-acyl-sn-glycerol- 1-phosphate bifunctional D-glycero- serine 1-acyl-sn-glycerol- RS00985 biosynthesis II (late a polycistronic purine nucleotides degradation II (aerobic) 5'-triphosphate UDP-N- rhamnosidase: protein kinase: 2 small subunit: diphosphate ribonucleotide- L-alanyl-γ-D- α-D-glucosamine bifunctional 3-phosphate D-alanine bifunctional D-glycero- recombinational demethylmenaquinone pseudouridine(38- acetyltransferase: carboxylase L-cysteine desulfurase cobalt incorporation) 4-amino-2-methyl-5- tRNA charging biosynthesis tRNA precursor superpathway of pyrimidine formaldehyde oxidation BM400_RS14040 crossover junction beta-D-manno- 3-phosphate reductase cys gln undecaprenyldiphospho- adenosylcobinamide acetylmuramate:L- BM400_RS14125 40) synthase TruA: carboxyltransferase BM400_RS16610 diphosphate uroporphyrinogen-III HMP-PP glutaminyl-tRNA formate assimilation into 5,10- glutamyl-L-lysyl- acyltransferase: beta-D-manno- junction endodeoxyribonuclease heptose-7-phosphate methyltransferase/2- BM400_RS06310 acyltransferase: pyrimidinemethanol deoxyribonucleosides degradation VII (THF pathway) subunit beta: reductase uroporphyrinogen-III cys uroporphyrinogen thiamine phosphate arginine- biosynthesis via tyr methylenetetrahydrofolate D-alanyl-D-alanine muramoylpentapeptide beta-N- kinase/ alanyl-gamma-D- alpha-L- methoxy-6-polyprenyl-1,4- serine/threonine BM400_RS15090 subunit alpha: nickel-dependent cysteine hydroxymethylpyrimidine/ ditrans,octacis- BM400_RS03325 heptose-7-phosphate RuvC: BM400_RS12510 kinase/D-glycero- serine BM400_RS03325 BM400_RS14375 RS08180 RS11225 uroporphyrinogen-III cysteine ATP AMP 2'-deoxycytidine acetylglucosaminyltransferase: adenosylcobinamide- glutamyl- meso- rhamnosidase: BM400_RS13990 subunit beta: desulfurase: decarboxylase: synthase: -tRNA transamidation [+ 3 isozymes] kinase/D-glycero- beta-D-manno- benzoquinol methylase protein kinase: RluA family acetyltransferase: hydrogenase cysteine phosphomethylpyrimidine arg tyrosinase: formaldehyde undecaprenyldiphospho- a 2,3,4-saturated Holliday junction a 1-acyl-2-[+ 3 isozymes] BM400_RS14375 RS20025 C-methyltransferase: desulfurase: GTP BM400_RS06775 BM400_RS05275 ligase: formate murG phosphate diaminopimelate BM400_RS04160 UbiE: BM400_RS15625 BM400_RS14975 [+ 4 isozymes] large subunit: ribonucleoside- BM400_RS20530 kinase: BM400_RS14020 BM400_RS09320 N-acetyl-(N-acetyl-β-D- beta-D-manno- resolvase RuvX: heptose 1-phosphate pseudouridine BM400_RS14600 cobA BM400_RS20530 desulfurase: coproporphyrinogen III Glu a tRNA precursor bifunctional cytidine deaminase: guanylyltransferase: 1,2-diacyl-sn UDP-N-acetylmuramoyl-ligase: mpl a non resolution of palmitoyl-sn diphosphate thiamine phosphate argS an L-arginyl- dopaquinone UDP acyl-carrier protein heptose 1-phosphate adenylyltransferase MQH a [protein] (L-serine/L- synthase: malonyl-CoA BM400_RS16625 ribonucleoside- cysteine BM400_RS20530 5-(2-hydroxyethyl) Gln glucosaminyl)muramoyl- -glycerol 3- L-alanyl-γ-D- rhamnosylated β-L- recombinationalBM400_RS17270 2 O-acetyl-L-serine -glycerol 3- precorrin-1 cysteine GTP 3',8- Arg glutamyl-tRNA with a 5' exoribonuclease: metallophosphatase/ BM400_RS08270 BM400_RS18225 threonine) phosphate reductase diphosphate HMP-P synthase: thiE [tRNA ] a 5,10- 10 γ a purine adenosyl- adenylyltransferase HldE: BM400_RS00910 H O desulfurase: L-alanyl- -D-glutamyl-L- 38- 2 -4-methylthiazole Arg synthetase: BM400_RS00235 an N - phosphate glutamyl-meso-2,6- rhamnosyl rhamnopyranose junction phosphate subunit alpha: RS12675 RS14335 desulfurase: cysteine cyclase a tRNA extension and a tRNA precursor 5'-nucleotidase: thymidine methylenetetrahydrofolate ribonucleoside cobinamide HldE: a pseudouridine reductase BM400_RS02085 uroporphyrinogen-III a carboxy- thiamine phosphate lysyl-D-alanyl-D-alanine diaminopimeloyl- acceptor formation of two D-glycero-β-D-BM400_RS13695 BM400_RS02085 desulfurase: hydroxymethylpyrimidine/ BM400_RS08375 a long 3' trailer with a 5' BM400_RS07335 IMP 2'-deoxyuridine formyltetrahydrofolate 40 in tRNA BM400_RS14380 subunit alpha: C-methyltransferase: MoaA: an L-glutamyl- bifunctional 5,10- 5'-diphosphate phosphate BM400_RS13695 RS03250 an [L-cysteine adenylated phosphomethylpyrimidine thymidine D-alanine ADP-D-glycero-β- intact strands manno-heptose an S-sulfanyl-[L- BM400_RS02085 moaA [tRNA Gln ] extension and a bifunctional 5,10- CDP BM400_RS14380 cobA [small subunit of protoporphyrinogen IX thiamine-phosphate GMP phosphorylase: methylenetetrahydrofolate D-manno-heptose 1,7-bisphosphate cysteine desulfurase] desulfurase]-S- an [L-cysteine (8S)-3',8-cyclo-7,8- kinase: BM400_RS14020 leucodopachrome short 3' extension adenosine methylenetetrahydrofolate 4-methyl-5-(2- kinase: thiL IMP dehydrogenase: dehydrogenase/5,10- GDP sulfanyl-L-cysteine desulfurase]-S- molybdopterin Asp-tRNA(Asn) RNase BN BM400_RS08265 precorrin-2 dihydroguanosine phosphooxyethyl) ribonuclease PH: ribonuclease uracil dehydrogenase/5,10- RS12680 RS02935 cysteine sulfanyl-L-cysteine synthase] HMP-PP protoporphyrinogen cysteine-- /Glu-tRNA(Gln) ribonuclease: bifunctional BM400_RS19035 methenyltetrahydrofolate 5'-triphosphate thiazole cys BM400_RS09640 P protein adenosine deaminase: add phosphorylase: thymine methenyltetrahydrofolate oxidase: hemG thiamine diphosphate tRNA ligase: amidotransferase BM400_RS00235 cyclohydrolase: RS17180 desulfurase: a ThiS sulfur- cyclic pyranopterin component: adenosine deaminase: metallophosphatase/ cyclohydrolase: BM400_RS08265 BM400_RS04615 an S-sulfanyl-[cysteine BM400_RS20530 BM400_RS02250 an L-cysteinyl- subunit GatB: 5'-nucleotidase: carrier protein monophosphate thiamine phosphate rnpA BM400_RS00990 XMP BM400_RS04615 a ring-opened 7- a DNA containing sn-glycero-3- N-acetyl-D- 1-[18-hydroxyoleyl]- 3-octaprenyl-4- (2R,3S)-3- UDP protoporphyrin IX lipoate biosynthesis [tRNA Cys ] BM400_RS04405 BM400_RS07335 a 5,10- 2-oxoglutarate adenosyl- 5'-deoxyadenosine acetyl-CoA L-iditol desulfurase]-[disordered- cysteine synthase synthase: L-dopachrome a tRNA precursor an apurinic/ galactosamine cob(I)yrinate thr and incorporation I Cys a tRNA a 5,10- methylguanine in DNA phosphoethanolamine ATP cobinamide ATP cobinamide GTP 2-lyso-phosphatidate hydroxybenzoate isopropylmalate dADP RS17550 form scaffold precorrin-3A a thiocarboxylated a tRNA [+ 3 isozymes] with a short methenyltetrahydrofolate sorbitol ribonucleotide- RS10730 desulfurase: MoaC: moaC BM400_RS05275 inosine bifunctional methenyltetrahydrofolate bifunctional DNA- apyrimidinic site glycerophosphodiester 6-phosphate 2-oxoglutarate a,c-diamide S-methyl-5'- 1-acyl-sn-glycerol- UbiD family 3-isopropylmalate acetyl-CoA C- [small subunit of cyclic ferrochelatase: precursor with uracil 2-deoxy-α-D- bifunctional DNA- N-acetylglucosamine- phosphate threonine/serine diphosphate protein] complex BM400_RS02085 trans, trans-farnesyl an L-glutaminyl- 3' extension guanosine bifunctional 5,10- formamidopyrimidine phosphodiesterase: ATP:cob(I)alamin dehydrogenase ATP:cob(I)alamin bifunctional thioadenosine 3-phosphate decarboxylase: dehydratase acyltransferase: dehydrogenase: ribonucleotide- RS05340 cysteine thiamine hemH a 5' extension metallophosphatase/ dehydratase: molybdopterin pyranopterin NAD an octanoyl-[acp] Gln ribose 1-phosphate bifunctional 5,10- formamidopyrimidine 6-phosphate reductase a [ThiI sulfur- a carboxy- diphosphate [tRNA ] purine-nucleoside 5'-nucleotidase: methylenetetrahydrofolate glycosylase/ BM400_RS06135 adenosyltransferase: E1 component: adenosyltransferase: adenosylcobinamide phosphorylase: acyltransferase: BM400_RS13000 large subunit: leuC BM400_RS17215 BM400_RS18895 diphosphate desulfurase: D-glyceraldehyde phosphate methylenetetrahydrofolate deacetylase: BM400_RS18935 carrier protein]-S- adenylated-[ThiS synthase] phosphate biosynthesis phosphorylation and lipoate-protein ribonuclease PH: purine-nucleoside glycosylase/ BM400_RS16485 BM400_RS03325 subunit beta: reductase 3-phosphate synthase: thiE ferroheme b ribonuclease: phosphorylase: BM400_RS07335 dehydrogenase/5,10- DNA-(apurinic or glycerophosphodiester BM400_RS16485 BM400_RS19975 kinase/ mtnP 3-octaprenyl-4- 3-isopropylmalate acetyl-CoA C- sorbitol BM400_RS20530 transhydrogenation ligase B: BM400_RS09640 dehydrogenase/5,10- DNA-(apurinic or BM400_RS10745 threonine BM400_RS14375 RS12175 tyr sulfanyl-L-cysteine sulfur-carrier protein] BM400_RS08315 phosphorylase: methenyltetrahydrofolate apyrimidinic site) lyase: ATP:cob(I)alamin adenosylcobinamide- [+ 3 isozymes] dehydratase acetyltransferase: dehydrogenase: subunit beta: 1-deoxy-D- IPP a [lipoyl-carrier gln rnpA methenyltetrahydrofolate phosphodiesterase: ATP:cob(I)alamin 2-oxoglutarate 5-deoxy-α-ribose 1-[18-hydroxyoeoyl]-2- hydroxybenzoate cysteine precorrin-3B AIR + BM400_RS03485 BM400_RS08315 apyrimidinic site) lyase: N-acetylglucosamine- adenine ammonia-lyase: ribonucleoside- BM400_RS14375 NAD 6 xanthosine 2-deoxy-D-ribose cyclohydrolase: BM400_RS05295 BM400_RS11560 adenosyltransferase: dehydrogenase: adenosyltransferase: phosphate carboxy-lyase: small subunit: leuD BM400_RS20505 BM400_RS01190 desulfurase: xylulose-5- protein] N - cyclohydrolase: 2,6-diamino-4- BM400_RS05295 1-phosphate [18-hydroxy-lioleoyl]-sn BM400_RS02650 RS15610 thiamine phosphate BM400_RS04615 an apurinic site sn-glycerol 6-phosphate adenosyl-BM400_RS18205 guanylyltransferase: (2S)-2- diphosphate phosphate NAD(+) kinase: an L-glutaminyl- hypoxanthine 5-phosphate BM400_RS18205 BM400_RS03480 -glycerol 3-phosphate BM400_RS20920 acetoacetyl-CoA keto-L-sorbose ribonucleoside- BM400_RS02085 phosphomethylpyrimidine octanoyl-L-lysine guanine BM400_RS04615 hydroxy-5-(N-methyl) endonuclease ethanolamine deacetylase: nagA isopropylmalate 2-oxobutanoate a [cysteine desulfurase]- molybdopterin BM400_RS20990 [tRNA Gln ] an N 10 - within DNA 3-phosphate PPP adenosylcobinamide D-galactosamine PPP cobyrinate BM400_RS18225 reductase diphosphate synthase: dxs lipoyl formamidopyrimidine i NADH CO succinyl-CoA i 2-octaprenylphenol synthase ThiC: thiamine- Gln a 5,10- III: nth acetate 2 adenosylcobinamide- RS14620 S-sulfanyl-[disordered- a thiocarboxy- DMAPP NADP + a tRNA an uncharged deoxyribose- formyltetrahydrofolate 6-phosphate a,c-diamide subunit alpha: reductase BM400_RS08945 1-deoxy-D-xylulose synthase: purine-nucleoside a 3'-terminal a 5'-phospho- GDP 2-iminoacetate phosphate methylenetetrahydrofolate BM400_RS14380 form scaffold precorrin-4 [ThiS-Protein] lipA tRNA xanthine dehydrogenase: phosphorylase: phosphate unsaturated sugar [DNA] subunit alpha: 5-phosphate kinase: thiL formyltetrahydrofolate protein] complex HMP-P prenyltransferase: NAD(P) a [lipoyl-carrier aldolase: deoC dUDP BM400_RS14380 RS06170 BM400_RS09220 BM400_RS08315 deformylase: purU cysteine molybdopterin BM400_RS00955 transhydrogenase protein]-N 6 - thiazole synthase: thiamine diphosphate ADP desulfurase: hydroxymethylpyrimidine/ subunit beta: RS12105 adenine lipoyl-L-lysine formate BM400_RS12500 geranyl xanthine acetaldehyde D-glyceraldehyde 3-phosphate BM400_RS20530 phosphomethylpyrimidine dinucleotide BM400_RS07185 Glu diphosphate queuosine biosynthesis cysteine precorrin-5 kinase: BM400_RS14020 2-[(2R,5Z)-2-carboxy- molybdopterin [+ 2 isozymes] an L-glutamyl- RS17740 prenyltransferase: xanthine dehydrogenase: all trans-decaprenyl- 1-stearoyl- a 3,5,7,9,11,13,15- 4-(cytidine 5'- a 1-alkyl-sn an insertion desulfurase: 4-methylthiazol-5(2H)- molybdenumtransferase Glu a 7,8-dihydro-8- (R)-methylmalonyl- dCDP a [protein]-L- HMP-PP NADPH [tRNA ] BM400_RS09220 a [ribosomal protein a (6S)-5- a [ThiI sulfur-carrier adenosylcobinamide a ribonucleoside BM400_RS02085 ylidene]ethyl phosphate MoeA: BM400_RS19505 BM400_RS00955 glu preQ a sulfurated [sulfur carrier] 2-methoxy-6- a palmitoyl-[acp] sn-glycerol Glu cys hepta-oxo- diphospho)-2-C- CoA -glycerol 3- sequence met methionine siroheme biosynthesis tetrahydrofolate biosynthesis a tRNA 0 S12] L-aspartate 89 a tRNA precursor CTP ATP oxoguanine in DNA formyltetrahydrofolate protein]-L-cysteine diphosphate RS08890 an S-sulfanyl-[cysteine MoO - NADPH-dependent 1,4-benzoquinol 3-phosphate bifunctional hexadecanoyl-[PKS-acp] methyl-D-erythritol methylmalonyl- phosphate ribonucleoside- element IS30 peptide- 2 bifunctional DNA- 1-acyl-sn-glycerol- cysteine aldo/keto 4-(cytidine 5'- ribonucleotide- desulfurase]-S- (2E,6E)-farnesyl thymine degradation urate acetyl-CoA MiaB/RimO family bifunctional bifunctional 1-acyl-sn-glycerol- diphosphate transposase: bifunctional molybdopterin (7,8-dihydropterin- 7-cyano-7- CCA tRNA formamidopyrimidine adenosylcobinamide CoA mutase: methionine thiamine phosphate menaquinol-7 biosynthesis Alcohol Degradation radical SAM demethylmenaquinone 3-phosphate folylpolyglutamate desulfurase: reductase: diphospho)- diphosphate 3-phosphate BM400_RS09115 glutamate N- sulfanyl-[disordered- precorrin-6A pyridoxal 5'-phosphate biosynthesis I cofactor diphosphate reductase, RS20365 synthase: uroporphyrinogen-III 6-yl)methyl 4-aminobenzoate deazaguanine nucleotidyltransferase: glycosylase/ acyltransferase: BM400_RS02085 kinase/ BM400_RS15110 2-C-methyl-D- reductase BM400_RS12135 (R)-S-oxide form scaffold thymine methylthiotransferase: methyltransferase/2- synthase/ acyltransferase: adenosylcobalamin- transposase: acetyltransferase/ BM400_RS05275 uroporphyrinogen-III diphosphate all-trans- reductase QueF: BM400_RS15160 DNA-(apurinic or BM400_RS03325 adenosylcobinamide- erythritol kinase: subunit beta: methylmalonyl- reductase: protein] complex D-erythrose 2-carboxy-1,4- dihydrothymine glycerol and glycerophosphodiester degradation BM400_RS18725a [ribosomal protein methoxy-6-polyprenyl-1,4- dihydrofolate cysteine 9-hydroxy-3,5,7,11,13,15-[+ 6 isozymes] BM400_RS08275 dependent: an insertionBM400_RS11085 amino-acid RS21425 cysteine C-methyltransferase: 7,8- heptaprenyl isoleucine-- BM400_RS11290 an unsulfurated CCA tRNA apyrimidinic site) lyase: phosphate BM400_RS07895 BM400_RS14375 CoA mutase: msrB thiamine 4-phosphate naphthoquinol ile dehydrogenase: 5'-deoxyadenosine met S12]-3-methylsulfanyl- benzoquinol methylase [+ 3 isozymes]1-stearoyl- synthase: desulfurase: hexaoxohexadecanoyl- 2-phospho-4-(cytidine a 2-acyl-1-alkyl-[+ 3 isozymes] BM400_RS19655 sequence IS30 acetyltransferase cobA diphosphate tRNA ligase: preQ superpathway of purine deoxyribonucleosides degradation [sulfur carrier] BM400_RS05295 guanylyltransferase: desulfurase: phosphate dihydropteroate 1 BM400_RS15875 89 nucleotidyltransferase: UbiE: BM400_RS15625 BM400_RS03330 BM400_RS20530 [+ 2 isozymes] BM400_RS01690 ArgJ: peptide- precorrin-1 a glycerophosphodiester L-aspartate an apurinic site 7,8-dihydro- 6-methoxy-3-methyl- 2-palmitoyl- a [ThiI sulfur- [PKS-acp] 5'-diphospho)-2-C- a 2'- sn-glycerol [+ 2 isozymes] with integrated BM400_RS20530 BM400_RS14315 an L-isoleucyl- 5,6-dihydrothymine a tRNA BM400_RS02265 acyl-carrier protein a (6S)-5- BM400_RS18225 precorrin-6B synthase: thiE bifunctional demethylmenaquinol-7 tRNA guanosine(34) 2-all-trans-decaprenyl- sn-glycerol ala carrier protein]-S- methyl-D-erythritol deoxyribonucleoside succinyl-CoA 3-phosphate transposon BM400_RS12940 methionine RS01895 [tRNA Ile ] within DNA 8-oxoguanine adenosyl-cobinamide CDP cysteine NAD biosynthesis I (from aspartate) folylpolyglutamate containing a formyltetrahydrofolate N-acetyl-L- (R)-S-oxide uroporphyrinogen-III Ile transglycosylase dihydropyrimidinase: 1,4-benzoquinol 3-phosphate sulfanyl-L-cysteine 5'-diphosphate RS00565 4-phospho- a tRNA 2'-deoxyguanosine 3' CCA end phosphate desulfurase: C-methyltransferase: synthase/ bifunctional Tgt: glycerophosphodiester methionine reductase: thiamine phosphate D-erythronate hydA BM400_RS02085 dihydrofolate demethylmenaquinone phosphodiesterase: glycerol msrB a [cysteine asp cobA BM400_RS03035 hydantoinase: 2'-deoxyadenosine a protein-L- synthase: methyltransferase/2- BM400_RS06135 desulfurase]-(S- thiamine- a 7-aminomethyl-7- BM400_RS02505 methionine- RS18915 precorrin-7 precorrin-2 methoxy-6-polyprenyl-1,4- 34 sulfanyl) -[disordered- phosphate L-aspartate oxidase: nadB BM400_RS03330 deazaguanosine purine-nucleoside glycerophosphodiester glycerol (R)-S-oxide 2 benzoquinol methylase 3-(carbamoylamino)- RS12050 form scaffold kinase: thiL (3R)-3-hydroxy-2-oxo- 7,8-dihydrofolate leu leucine-- in tRNA phosphorylase: phosphodiesterase: kinase: 2-iminosuccinate bifunctional precorrin- adenosine UbiE: BM400_RS15625 tRNA ligase: tRNA preQ1(34) S- 2-methylpropanoate protein] complex 4 phosphooxybutanoate 2 dehydrogenase/ monoglutamate deaminase: add BM400_RS08315 BM400_RS11560 glpK purine-nucleoside a dimer of non-adjacent 2'- 1-stearoyl- 2-methoxy-6-all 1-stearoyl- a 6-(N-acetyl-α- 1402 2251 a 1-acyl-sn a (7Z)-3- an [amino group thiamine diphosphate phosphoserine BM400_RS09570 an L-leucyl- adenosylmethionine S-methyl-L- a nucleoside a cytidine guanosine xylitol UDP quinolinate synthase sirohydrochlorin menaquinol-7 adenosine an oleoyl-[acp] sn-glycerol trans-heptaprenyl- a stearoyl-[acp] sn-glycerol rutin a ribonucleic acid adenosylcobinamide (Z)-hex-3-en-ol -glycerol 3- oxotetradec- [tRNA Leu ] ribosyltransferase- phosphorylase: L-homocysteine deoxycytidine and thymidine in DNA D-glucosaminyl)- in 16S rRNA in 23S rRNA carrier protein]- RS18255 precorrin-8x transaminase: ferrochelatase: heme a biosynthesis deaminase: sn-glycerol methionine triphosphate ribonucleoside- NadA: BM400_RS02070 a tRNA Leu BM400_RS08315 deoxyribodipyrimidine 3-phosphate 1,4-benzoquinol 3-phosphate alpha-L- bifunctional 1-phosphatidyl- 16S rRNA 23S rRNA NAD(P)- NAD(P)- phosphate 7-enoyl-[acp] C-terminal-γ- RS04080 BM400_RS11695 isomerase QueA: bifunctional homocysteine 1-acyl-sn-glycerol- bifunctional 1-acyl-sn-glycerol- DNA- 1-acyl-sn-glycerol- 3-oxoacyl- a [cysteine desulfurase]- BM400_RS18430 purine ribonucleosides degradation BM400_RS00990 3-phosphate photolyase: rhamnosidase: adenosylcobinamide GlcNAc-PI de- (cytosine(1402)-N(4) dependent alcohol dependent alcohol diphosphate BM400_RS21280 (R)-3-amino-2- purine-nucleoside S-methyltransferase/ 3-phosphate demethylmenaquinone 3-phosphate directed RNA 1D-myo-inositol (guanosine(2251) 3-phosphate [acyl-carrier- (L-glutamate 5- 4-phosphooxy- quinolinate a 7,8-dihydrofolate N-acetylase: reductase, [scaffold protein- ferroheme b methylpropanoate glycerol-3- BM400_RS05535 BM400_RS14040 kinase/ )-methyltransferase -2'-O)- dehydrogenase: dehydrogenase: semialdehyde-2-N-acetyl- sirohydrochlorin 34 phosphorylase: methylenetetrahydrofolate acyltransferase: methyltransferase/2- acyltransferase: polymerase 6-(α-D- acyltransferase: protein] (2Fe-2S)] complex L-threonine protoheme IX an epoxyqueuosine adenosylcobinamide- BM400_RS10420 RsmH: BM400_RS04005 BM400_RS04005 adenosylcobalamin- gamma- phosphopantothenate biosynthesis I nicotinate-nucleotide BM400_RS08315 phosphate reductase: BM400_RS09995 deoxyribodipyrimidine BM400_RS03325 methoxy-6-polyprenyl-1,4- BM400_RS03325 alpha-L- subunit methyltransferase BM400_RS08275 reductase: yl)-L-glutamate bis(guanylyl molybdenum in tRNA glucosaminyl)- dependent: RS13155 4-hydroxythreonine- bifunctional precorrin- farnesyltransferase: adenosine 2'-deoxyinosine α dehydrogenase: photolyase: rhamnosidase: phosphate acetate 4 BM400_RS09515 RlmB: [+ 2 isozymes] [+ 2 isozymes] glutamyl- hydrogenobyrinate diphosphorylase 2-deoxy- -D-ribose 1-phosphate met [+ 31-stearoyl-2- isozymes] benzoquinol methylase [+ 3 isozymes] omega: rpoZ 1-phosphatidyl- an N - a 1,2-diacyl-[+ 3 isozymes] fabG RS18295 4-phosphate cyoE cofactor) biosynthesis 1-stearoyl-2- guanylyltransferase: BM400_RS19655 phosphate D-glyceraldehyde (carboxylating): nadC 2 dehydrogenase/ val epoxyqueuosine BM400_RS06180 BM400_RS03190 UbiE: BM400_RS15625 BM400_RS04160 1402 BM400_RS06940 D-xylopyranose (Z)-3-hexanal 3-methyl-2-oxobutanoate pyruvate valine--tRNA ligase: acyl-carrier protein oleoyl-sn-glycerol 6-methoxy-3-methyl-2- stearoyl-sn β-L- [+ 3 isozymes] 1D-myo-inositol methylcytidine 2-O- sn-glycerol a (3R,7Z)-3-[+ 7 isozymes] an [amino group hydrogenobyrinate 3-phosphate dehydrogenase sirohydrochlorin ferroheme o MoO - reductase: queG adenosine deaminase: add acyl-carrier protein quercetin- BM400_RS18225 [+ 2 isozymes] reductase: a [co-chaperone]- a tetrahydrofolate 2 a thymine in DNA a cytosine in DNA 3-phosphate all-trans-heptaprenyl- a ribonucleic acid in 16S rRNA methylguanosine 2251 3-phosphate PdxA: pdxA nicotinate-nucleotide molybdopterin BM400_RS06120 an L-valyl- DHAP -glycerol 3- rhamnopyranose 3-glucoside adenosyl-cobinamide dUDP hydroxytetradec- carrier protein]-argC [scaffold protein- a,c-diamide synthase: 3-methyl-2-oxobutanoate ferrochelatase: a queuosine 34 adenosine deaminase: 1-deoxy-D- diphosphorylase [tRNA Val ] 1,4-benzoquinol phosphate in 23S rRNA 7-enoyl-[acp] C-terminal-γ- BM400_RS16515 (2S)-2-amino-3-oxo-4- BM400_RS18430 cofactor bis(molybdenum BM400_RS00990 phosphate RS11250 (2Fe-2S)] complex hydroxymethyltransferase: xylulose-5- (carboxylating): a tRNA Val in tRNA (5-phospho- RS14570 phosphooxybutanoate 5,6-dimethylbenzimidazole cofactor) synthase: 2-deoxy-D-ribose 5-phosphate hydrogenobyrinate panB phosphate BM400_RS02080 L-glutamyl)- siroheme biosynthesis I (aerobic) BM400_RS11325 xanthosine adenosine inosine guanosine a,c-diamide synthase: ferroheme i bis(molybdenum L-glutamate 2-dehydropantoate dxs NaMN cofactor) deoxyribose- a [chaperone-ATP]- cobalt chelatase: riboflavin 3-amino-1- molybdenum cofactor lipoprotein posttranslational phosphate Polymeric Compound RS13235 [co-chaperone]- BM400_RS16455 2-dehydropantoate 2- 1-deoxy-D- nicotinate (nicotinamide) bifunctional riboflavin alanine- 2-methoxy-6-all RS12415 modification purine-nucleoside purine-nucleoside purine-nucleoside purine-nucleoside aldolase: deoC Degradation a (2R)-2-hydroxy 2-methylacetoacetyl- 3-oxopentanoyl- a dimer of non- a [release factor]- a (3R)-3- a (3R)-3- a (5Z)-3- [scaffold protein- xylulose 5- hydroxyacetone guanylyltransferase: -tRNA 1-myristoylglycerol 1-myristoylglycerol glycerophosphoserine leukotriene-D4 a cytosine in DNA a (9Z)-3-oxo- ethanol DHAP cob(II)yrinate reductase: BM400_RS15690 nucleotide kinase/FMN ala even numbered a palmitoleoyl-[acp] a myristoyl-[acp] trans-octaprenyl- adjacent 2'- hydroxyhexacosanoyl- hydroxydocosanoyl- oxododec- 1-phosphate BM400_RS11325 phosphorylase: phosphorylase: phosphorylase: phosphorylase: 3-phosphate 3-phosphate CoA CoA L-glutamine octadec-9-enoyl-[acp] (2Fe-2S)] complex a,c-diamide phosphate adenylyltransferase: nadD adenylyltransferase: ligase: a [prolipoprotein]- alginate degradation 1,4-benzoquinol acetyl-CoA C- acetyl-CoA C- DNA cytosine β-alanine hydroxyferroheme i bis(guanylyl BM400_RS08315 BM400_RS08315 BM400_RS08315 BM400_RS08315 straight chain 2,3,4- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional glycerophosphodiester deoxycytidines membrane peptide chain 3-oxoacyl-[acyl- NAD(P)- [acp] 3-hydroxyacyl- [acp] 3-hydroxyacyl- NAD(P)- 5-enoyl-[acp]3-oxoacyl- (R)-pantoate BM400_RS07740 alaS an L-alanyl- L-cysteine acetaldehyde D-glyceraldehyde 3-phosphate long-chain fatty molybdopterin saturated fatty acid 3-phosphate 3-phosphate phosphodiesterase: acyltransferase: acetyltransferase: in DNA deoxyribodipyrimidine dipeptidase: release factor methyltransferase: carrier-protein] dependent alcohol dependent [acyl-carrier- nicotinate adenine dinucleotide Ala demethylmenaquinone [acyl-carrier- [acyl-carrier- FMN [tRNA ] acid--CoA ligase: BM400_RS06135 BM400_RS17215 BM400_RS20505 BM400_RS12655 N(5)-glutamine BM400_RS00645 dehydrogenase: glycerol-3- RS03620 RS20645 cofactor) Ala alginate acyltransferase: acyltransferase: methyltransferase/2- photolyase: reductase: fabG protein] protein] protein] a tRNA α-D-ribose-1-phosphate aBM400_RS16050 (R)-2-hydroxy even pantoate--beta-alanine di-trans,poly-cis NAD+ synthetase, 4-aminobenzoate BM400_RS03325 BM400_RS03325 methoxy-6-polyprenyl-1,4- glycerophosphodiester acetyl-CoA C- acetyl-CoA C- BM400_RS05535 [+ 2 isozymes] methyltransferase: DNA cytosine [+ 7 isozymes] BM400_RS04005 dehydratase dehydratase phosphate reductase: a [chaperone- pyridoxine NAD+ synthase: numbered straight an [2Fe-2S] ligase: BM400_RS02060 -undecaprenyl glutamine dependent: biosynthesis a [prolipoprotein]- diphosphate AMP benzoquinol methylase phosphodiesterase: acetyltransferase: acyltransferase: prmC methyltransferase: a (3R,9Z)-3-hydroxy- [+ 2 isozymes] FabZ: fabZ FabZ: fabZ dehydrogenase: fabG ADP]-[disordered- thioredoxin poly(beta-D- chain 2,3,4-saturated [+ 31-myristoyl-2- isozymes] [+ 3 isozymes] deoxyribodipyrimidine leukotriene-E4 gly 5 phosphate biosynthesis 5'-phosphate BM400_RS11340 ferroheme a S-methyl-5'- a [release factor]-N octadec-9-enoyl-[acp] gpsA cluster protein pathway BM400_RS11340 (S-diacylglyceryl) dimyristoyl UbiE: BM400_RS15625 BM400_RS11560 BM400_RS20505 BM400_RS17215 photolyase: BM400_RS03775 acetaldehyde a (2E)-hexacos- a (2E)-docos- [+ 7 isozymes] form scaffold thioadenosine UTP and CTP dephosphorylation I acetyl-CoA pyrimidine deoxyribonucleotides mannuronate) fatty acyl CoA acyl-carrier protein palmitoleoyl acyl-carrier protein 6-methoxy-3-methyl- -methyl-L-glutamine a 5-methylcytosine a (3R,5Z)-3- (2E,6E)-farnesyl pyridoxamine 5'- folate polyglutamylation chorismate -L-cysteine phosphatidate sn-glycerol 2-enoyl-[acp] 2-enoyl-[acp] sn-glycerol RS13100 protein] complex + FMNH α 2-all-trans-octaprenyl- acetyl-CoA propanoyl-CoA propanoyl-CoA acetyl-CoA BM400_RS03190 RS18890 (R)-pantothenate NAD 2 degradation II dephosphorylation lyase: 4-deoxy- -L- phosphatidate ser in DNA hydroxydodec- an oxidized diphosphate phosphate oxidase: aminodeoxychorismate asparagine-- 3-phosphate a cytosine in DNA 3-phosphate di-trans,poly-cis- asn S-methyl-5'- D-ribose 5-phosphate BM400_RS08035 erythro-hex-4- 1,4-benzoquinol 5-enoyl-[acp] signal UTP nucleoside triphosphate thioredoxin BM400_RS13620 a tetrahydrofolate 5,6-dimethylbenzimidazole synthase, tRNA ligase: pantothenate kinase: decaprenylcistransferase: thioadenosine pyrophosphohydrolase: alginate lyase: enopyranuronate- component I: pabB BM400_RS07850 peptidase S-methyl-5'- BM400_RS06085 di-trans,octa-cisuppS [+ 2 isozymes] synthase: bluB 4-amino-4- an L-asparaginyl- α-L-guluronate an [Fe-S cluster a [disordered- Asn II: lspA thioadenosine CTP synthase: pyrG BM400_RS21120 BM400_RS08040 [tRNA ] a [2-oxoglutarate- 1-cis- 2-methoxy-6-all 6-methoxy-2-all- 3-benzyl-3,6 - 1518 a (3R)-3- a (3R,7Z)-3- a (3R)-3- -undecaprenyl deoxychorismate dCTP dCMP adenine / 1-myristoylglycerol a [protein]-L- RS20240 RS08585 biosynthesis form [Fe-S] cluster PLP bifunctional serine Asn phosphorylase: 1-palmitoylglycerol DMKH2-10 an unsulfurated L-arabinitol a 3-oxoicosanoyl- D-threo-isocitrate thioredoxin- (R)-4'-phosphopantothenate 5,6-dimethylbenzimidazole tRNA dehydrogenase a sulfurated a palmitoleoyl-[acp] vaccenoylglycerol- a myristoyl-[acp] trans-nonaprenyl- trans-octaprenyl- bis(cysteinylglycine) cys 1519 hydroxytetracosanoyl- hydroxytetradec- hydroxyglutaryl- diphosphate 4-deoxy-α-L- SAM adenine in 16S rRNA 3-phosphate methionine chaperone]-ATP scaffold protein] folylpolyglutamate hydroxymethyltransferase: glyA aminodeoxychorismate an (S-diacyl- mtnP CTP UMP 6 3-phosphate [sulfur carrier] [acp] disulfide undecaprenyl- a lipoprotein E2 protein] N - [sulfur carrier] 3-phosphate 1,4-benzoquinol 1,4-benzoquinone bifunctional - 6-(hydroxymethyl) cysteine ribosomal RNA NAD(P)- 3-oxoacyl-ACP isocitrate/ [acp] 7-enoyl-[acp] [acp] methyl ester peptide- sn-glyceryl) erythro-hex-4- 1-acyl-sn-glycerol- 1-acyl-sn-glycerol- bifunctional bifunctional 1-acyl-sn-glycerol- 3-hydroxyacyl- 3-hydroxyacyl- 3-hydroxyacyl- reductase: adenosylcobalamin synthase/ an N 10 - lyase: pabB signal peptide 5-MTR-1-P dUTP diphosphatase: octanoyl-L-lysinelipoyl -diketopiperazinemembrane small subunit dependent alcohol isopropylmalate methionine diphosphate bifunctional enopyranuronate- 3-phosphate 3-phosphate demethylmenaquinone demethylmenaquinone demethylmenaquinone desulfurase: 3-phosphate reductase: [acyl-carrier- [acyl-carrier- [acyl-carrier- dihydrofolate a 5,10- -L-cysteinyl- BM400_RS00790 synthase: dipeptidase: trxB phosphatase: salvage from cobalamin formyltetrahydrofolate methyltransferase/2- BM400_RS02085 methyltransferase dehydrogenase: BM400_RS02475 dehydrogenase (S)-S-oxide methylenetetrahydrofolate 4-aminobenzoate [apolipoprotein] metallophosphatase/ β-D-mannuronate a [2-oxoglutarate acyltransferase: acyltransferase: methyltransferase/2- methyltransferase/2- acyltransferase: protein] protein] protein] RS20960 synthase: nucleoside triphosphate lipA BM400_RS12655 A: rsmA BM400_RS04005 family protein: reductase: RS14745 BM400_RS20695 bifunctional aspartate-- 5'-nucleotidase: an unsulfurated dehydrogenase BM400_RS03325 BM400_RS03325 methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- methoxy-6-polyprenyl-1,4- cysteine N 6 -dimethyladenine 1518 BM400_RS03325 [+ 7 isozymes] dehydratase dehydratase dehydratase menaquinol-6 biosynthesis cob(I)alamin BM400_RS03330 bifunctional menaquinol-9 biosynthesis asp CMP pyrophosphohydrolase: 5'-deoxyadenosine met 3-benzyl-3,6 - a (3R)-3- di-trans,octa-cis folylpolyglutamate BM400_RS07335 6 benzoquinol methylase [+ 2 isozymes] 6 1519 [+ 2 isozymes] BM400_RS20375 msrA guanylyl molybdenum tRNA ligase: BM400_RS21120 [sulfur carrier] E2 protein] N [+ 1-cis-vaccenoyl-3 isozymes] [+ 3 1-palmitoyl-isozymes] benzoquinol methylase benzoquinol methylase bis(cysteinyl)- 6- desulfurase: /N -dimethyladenine 1-myristoyl-2-[+ 3 isozymes] hydroxyicosanoyl- FabZ: fabZ FabZ: fabZ a (2E)- FabZ: fabZ a reduced -undecaprenyl ATP:cob(I)alamin folylpolyglutamate synthase/ bifunctional UbiE: BM400_RS15625 gly L-arabinopyranose a (2E)-tetracos- a trans-∆ 3 -cis-∆ 7 - [+ 2 isozymes] cofactor biosynthesis BM400_RS05730 an L-aspartyl- a peptide dUTP dUMP -lipoyl-L-lysine acyl-carrier protein 2-palmitoleoyl acyl-carrier protein 2-myristoyl 6-methoxy-3-methyl-2-UbiE: BM400_RS15625 3-methyl-6-methoxy-UbiE: BM400_RS15625 (hydroxymethyl) BM400_RS20530 in 16S rRNA palmitoleoyl [acp] 2-oxoglutarate enoylglutaryl- a protein-L- thioredoxin menaquinol-8 biosynthesis phosphate adenosyltransferase: synthase/ demethylmenaquinol-9 an N-acyl-(S- metallophosphatase/ uridine demethylmenaquinol-6 a tetrahydrofolate dihydrofolate asp a 4-deoxy-α-L- menaquinol-10 a sulfurated 2-enoyl-[acp] tetradecenoyl-[acp] MoO - BM400_RS16485 dihydrofolate [tRNA ] phosphatidate phosphatidate all-trans-nonaprenyl- 2-octaprenyl-1,4- -diketopiperazine ala phosphatidate [acp] methyl ester methionine- bifunctional 2 synthase: bifunctional asp diacyl-sn-glyceryl) 5'-nucleotidase: [sulfur carrier] RS04980 geranyl diphosphate tRNA erythro-hex-4- 1,4-benzoquinol benzoquinone (S)-S-oxide RS03230 molybdopterin synthase: -L-cysteinyl- BM400_RS07335 demethylmenaquinone demethylmenaquinol-8 ATP:cob(I)alamin BM400_RS03330 demethylmenaquinone biosynthesis 5-hydroxy-CTP 5-hydroxy-CMP enopyranuronoside cofactor molybdenum cofactor adenosyltransferase: BM400_RS03330 [lipoprotein] methyltransferase/2- dimethylmenaquinone an N 10 - methyltransferase/2- cytidine guanylyltransferase: a 2-methoxy-6-all- methoxy-6-polyprenyl-1,4- methyltransferase: BM400_RS18205 a 5,10- methoxy-6-polyprenyl-1,4- a [pyruvate a (7Z,10Z,13Z,16Z a dimer of a cytidine 1402 1-cis- a (1->4)-β-D-xylan a (3R,5Z)-3- guanylyl BM400_RS11325 formyltetrahydrofolate IPP 1-palmitoylglycerol a CDP- sn-glycerol glycerophosphoglycerol DMKH2-13 a 3-oxohexacosanoyl- a 3-oxoglutaryl- (E)-2-hexenol benzoquinol methylase BM400_RS08830 adenosylcobalamin methylenetetrahydrofolate benzoquinol methylase dehydrogenase a sulfurated a palmitoleoyl-[acp] trans-polyprenyl- ,19Z)-3-oxodocosa- non-adjacent vaccenoylglycerol- oligosaccharide hydroxydodec- ser RS19690 molybdenum prenyltransferase: 4-deoxy-L- SAM 3-phosphate diacylglycerol 3-phosphate in 16S rRNA [acp] [acp] methyl ester IMP tyrosine-- E2 protein] N 6 - [sulfur carrier] 1,4-benzoquinol glycerophosphodiester 7,10,13,16,19-pentaenoyl-[acp] thymidines in DNA 16S rRNA 3-phosphate beta-xylosidase: NAD(P)- RS08580 UbiE: BM400_RS15625 [+ 2 isozymes] UbiE: BM400_RS15625 tyr 1-acyl-sn-glycerol- CDP-diacylglycerol-- bifunctional bifunctional 3-oxoacyl-ACP 3-oxoacyl-ACP 1-acyl-sn-glycerol- 3-oxoacyl-ACP 5-enoyl-[acp]3-hydroxyacyl- cofactor BM400_RS00955 tRNA ligase: 6 erythro-hex-4- lipoyl deoxyribodipyrimidine threonine/serine menaquinol-6 menaquinol-9 N -L- Aromatic Compound octanoyl-L-lysine phosphodiesterase: demethylmenaquinone (cytidine(1402)-2'-O) BM400_RS06425 dependent alcohol bifunctional menaquinol-8 geranyl enopyranuronate 3-phosphate glycerol-3-phosphate 3- demethylmenaquinone reductase: photolyase: reductase: 3-phosphate reductase: [acyl-carrier- dehydratase: BM400_RS00210 an L-tyrosyl- threonylcarbamoyladenosine 37 synthase: BM400_RS11560 -methyltransferase: xylan 1,4-beta- dehydrogenase: metallophosphatase/ diphosphate Degradation a [pyruvate acyltransferase: phosphatidyltransferase: methyltransferase/2- methyltransferase/2- BM400_RS02475 BM400_RS02475 acyltransferase: BM400_RS02475 protein] Tyr lipA BM400_RS05535 5'-nucleotidase: BM400_RS18935 [tRNA ] -modified tRNA biosynthesis Carbohydrate Degradation pgsA glycerophosphodiester methoxy-6-polyprenyl-1,4- rsmI xylosidase: BM400_RS04005 Tyr an unsulfurated dehydrogenase BM400_RS03325 methoxy-6-polyprenyl-1,4- a (3R,7Z,10Z,13[+Z ,167 isozymes]Z a 2'-O- a (3R)-3-[+ 7 isozymes] BM400_RS03325 a (3R)-3-[+ 7 isozymes] dehydratase RS19880 a tRNA protocatechuate 5'-deoxyadenosine met 1-(3-sn- deoxyribodipyrimidine BM400_RS16385 BM400_RS07335 L-serine 6 benzoquinol methylase phosphodiesterase: benzoquinol methylase 1402 [+ 2 isozymes] FabZ: fabZ RS04360 Aromatic Compound thr [sulfur carrier] E2 protein] N [+ 31-palmitoyl-2- isozymes] phosphatidyl) ,19Z)-3-hydroxydocosa- photolyase: methylcytidine hydroxyhexacosanoyl- 1,2-dicis-[+ 3 isozymes] hydroxyglutaryl- ammonia-lyase: degradation II (ortho- (4S,5S)-4,5- CMP UbiE: BM400_RS15625 β inosine a (2E,5Z)-dodeca- D-galactose degradation V (Leloir pathway) D-galactose degradation I (Leloir pathway) -lipoyl-L-lysine a 6-methoxy-3-methyl-UbiE: BM400_RS15625 BM400_RS06135 7,10,13,16,19-pentaenoyl-[acp] in 16S rRNA [acp] [acp] methyl ester -D-xylopyranose (E)-2-hexenal Biosynthesis threonylcarbamoyl- cleavage pathway) dihydroxy-2,6- acyl-carrier protein palmitoleoyl -sn-glycerol BM400_RS03190 vaccenoyl- BM400_RS20495 sn-glycerol menaquinol-13 3,5-dienoyl-[acp] AMP synthase: dioxohexanoate phosphatidate 3-phosphate 2-all-trans-polyprenyl- glycerol a thymine in DNA phosphatidate pyruvate chorismate biosynthesis I protocatechuate 3-phosphate BM400_RS14285 Chemoautotrophic β-D-galactose β-D-galactose 1,4-benzoquinol RS07090 tryptophan- a tRNA Trp Energy Metabolism RS09375 D-erythrose -tRNA threonylcarbamoyl- galactose galactose undecaprenyl-diphospho-N (R)-4'- 2-methoxy-6-all an [apo BCAA 1-cis- a (9Z)-3- 4-phosphate ligase: trpS AMP synthase: hydrogen mutarotase: mutarotase: 3-carboxy-cis 2-dehydro- adenosylcobinamide- α-ribazole 1-oleyl-2-lyso- 3-oxo- a (3R)-3- an L-tryptophanyl- γ α hesperidin DMKH2-11 a uracil in DNA a 3-oxopimeloyl- Fatty Acid and Lipid Biosynthesis Metabolic Regulator Biosynthesis Trp BM400_RS21025 ,cis-muconate 3-deoxy-D- -acetylmuramoyl-L-alanyl- - UDP-N-acetyl- -D-glucosamine phosphopantothenoyl- trans-hexaprenyl- a type IV prepilin dehydrogenase E2 protein] vaccenoylglycerol- oxohexadec- phosphatidate hydroxypimeloyl- [tRNA ] oxidation BM400_RS10925 BM400_RS10925 GDP 5'-phosphate FMN ATP [acp] methyl ester docosapentaenoyl-CoA dIDP 3-deoxy-7- L-threonylcarbamoyladenylate D-glutamyl-L-lysyl- D-alanine L-cysteine 1,4-benzoquinol alpha-L- uracil-DNA N 6 -dihydrolipoyl-L-lysine 3-phosphate 9-enoyl-[acp] 1-acyl-sn-glycerol- 3-oxoacyl- RS12035 I (aerobic) gluconate undecaprenyldiphospho- bifunctional adenosylcobinamide- bifunctional bifunctional prepilin peptidase: 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP [acp] methyl ester3-hydroxyacyl- phosphoheptulonate trp galactose galactose rhamnosidase: dihydrolipoyl nucleoside- 2-dehydro-3- GDP demethylmenaquinone BM400_RS12485 glycosylase: bifunctional riboflavin reductase: reductase: 3-phosphate [acyl-carrier- palmitate biosynthesis II (bacteria and plants) ppGpp biosynthesis Cell Structure Biosynthesis mutarotase: mutarotase: muramoylpentapeptide beta-N- phosphopantothenoylcysteine demethylmenaquinone 3-phosphate [acyl-carrier- RS15350 CDP-diacylglycerol biosynthesis III long-chain fatty trehalose synthase: H BM400_RS14040 BM400_RS09930 dehydrogenase: kinase/FMN acyltransferase: protein] diphosphate trehalose 2 deoxygluconokinase: acetylglucosaminyltransferase: decarboxylase/ ribazoletransferase: methyltransferase/2- methyltransferase/2- prepilin peptidase: acyltransferase: BM400_RS02475 BM400_RS02475 protein] acid activation BM400_RS13805 hydrogenase BM400_RS21335 BM400_RS21335 (2-carboxy- lpdA kinase: biosynthesis V biosynthesis IV BM400_RS17370 murG cobS alpha-L- methoxy-6-polyprenyl-1,4- uracil-DNA an [apo BCAA adenylyltransferase: BM400_RS03325 reductase: 6 ditrans,octacis-undecaprenyldiphospho- phosphopantothenate-- methoxy-6-polyprenyl-1,4- BM400_RS16880 BM400_RS03325 a (3R)-3-[+ 7 isozymes] a (3R,9Z)-3-[+ 7 isozymes] dehydratase an acetoacetyl-[acp] pppGpp peptidoglycan biosynthesis I (meso-diaminopimelate containing) 3-deoxy-7- an N -L- 2 small subunit: 2,5-dihydro- rhamnosidase: BM400_RS07740 fabG BM400_RS21345 DHAP a long-chain α-D-galactose α-D-galactose cysteine ligase CoaBC: coaBC adenosylcobalamin benzoquinol methylase benzoquinol methylase a cleaved type glycosylase: dehydrogenase E2 [+ 3 isozymes] FabZ: fabZ RS09305 α-maltose threonine-- threonylcarbamoyladenine 37 BM400_RS16610 5-oxofuran- UDP N-acetyl-(N-acetylglucosaminyl)muramoyl- a peptide 1-cis-vaccenoyl-[+ 3 isozymes] hydroxypimeloyl- hydroxyhexadec- dioleoyl (5Z,8Z,11Z,14Z,17Z) a (2E)- a glycogen phosphoheptulonate KDGP GMP BM400_RS04160 UbiE: BM400_RS15625 IV prepilin 6 FAD fatty acid UDP-N-acetyl- thr L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine 5'-phosphate UbiE: BM400_RS15625 BM400_RS10650 protein] N -lipoyl-L-lysine -3R-hydroxy- dITP 3-oxoacyl-ACP NAD(P)- long-chain fatty bifunctional (p)ppGpp maltose alpha-D- synthase: aroF tRNA ligase: in tRNA 2-yl)-acetate 4'-phosphopantetheine 6-methoxy-3-methyl-2- β-L- hesperitin-7-O- an apyrimidinic 2-palmitoleoyl [acp] methyl ester 9-enoyl-[acp] phosphatidate enoylpimeloyl- RS10345 α nickel-dependent galactokinase: galactokinase: menaquinol-11 uracil acid--CoA ligase: synthetase/guanosine- guanosine 3'- glucosyltransferase: -D-glucosamine BM400_RS03355 carboxymuconolactone all-trans-hexaprenyl- rhamnopyranose β-D-glucoside phosphatidate docosapentaenoyl-CoA [acp] methyl ester reductase: dependent an acyl-[acyl- 3-deoxy- an L-threonyl- hydrogenase galK galK site in DNA BM400_RS02475 glycerol-3- BM400_RS16050 3',5'-bis(diphosphate) 3'- diphosphate 5'- treS UDP-N-acetylglucosamine D-arabino- Thr decarboxylase: 1,4-benzoquinol carrier protein] a long-chain a maltodextrin [tRNA ] large subunit: galactokinase: pyrophosphohydrolase: α,α-trehalose 1-carboxyvinyltransferase: Thr galactokinase: BM400_RS06590 RS19030 [+ 7 isozymes] phosphate triphosphate 3'- heptulosonate a tRNA fatty acyl-CoA BM400_RS16625 BM400_RS11545 BM400_RS11545 BM400_RS00200 diphosphatase: malto- murA carboxymuconolactone a (3R)-3- dehydrogenase: 7-phosphate A(H2) adenine 2503 an electron- a [protein]- a damaged a (7Z)-3- a (3R)-3- RS19480 oligosyltrehalose α NADH H + NADH menadione H + a [protein]-L-lysine a 2-oxo a 3-oxotetracosanoyl- 1-palmitoylglycerol a DNA segment an alcohol butan-1-ol hydroxybutanoyl- gpsA BM400_RS00200 UDP-N-acetyl- - α-D-galactose α-D-galactose decarboxylase: DMK-12 L-ornithine a RNA-DNA hybrid oxohexacos- hydroxyicosanoyl- 3-dehydroquinate α UDP-α-D-glucose in 23S rRNA dGTP transfer quinone L-glutamine DNA pyrimidine 3-phosphate IDP synthase: treY D-glucosamine- Glycolysis UDP- -D-glucose BM400_RS06595 carboxylate [acp] recombinase [acp] synthase: aroB 1-phosphate 1-phosphate 23S rRNA NADH NADH oxidoreductase transglutaminase: bifunctional bifunctional DNA- ribonuclease HII: 3-oxoacyl-ACP 1-acyl-sn-glycerol- 7-enoyl-[acp]3-oxoacyl-ACP NAD(P)- NAD(P)- [acp] sn-glycerol (4,5-dihydro- deoxyguanosinetriphosphate ornithine- 3-hydroxyacyl- 3-hydroxyacyl- an acyl phosphate a maltooligosyl- enolpyruvate (adenine(2503)-C(2) oxidoreductase (quinone) subunit F: BM400_RS13735 demethylmenaquinone formamidopyrimidine BM400_RS18555 RecA: recA dependent alcohol dependent alcohol nucleoside- RS20620 3-phosphate -oxo-acid reductase: 3-phosphate reductase: [acyl-carrier- [acyl-carrier- GTP ppGpp trehalose UDP-N- ser glycolysis III (from glucose) 5-oxofuran- )-methyltransferase triphosphohydrolase: BM400_RS12455 diphosphate 3-dehydroquinate serine--tRNA ligase: (quinone) subunit F: transglutaminase: methyltransferase/2- transaminase: glycosylase/ ribonuclease HI: BM400_RS02475 acyltransferase: recombinase XerC: BM400_RS02475 dehydrogenase: dehydrogenase: protein] acetylenolpyruvoylglucosamine 2-yl)-acetate BM400_RS10655 RS04450 protein] RlmN: rlmN BM400_RS12455 NADH dehydrogenase BM400_RS13740 methoxy-6-polyprenyl-1,4- DNA-(apurinic or BM400_RS11110 BM400_RS12215 BM400_RS04005 kinase: malto- BM400_RS11255 an L-seryl- a protein with an rocD BM400_RS04530 a (3R)-3-[+ 7 isozymes] BM400_RS03325 a DNA segment a (3R,7Z)-3-[+ 7 isozymes] dehydratase dehydratase acyl-phosphate reductase: BM400_RS17140 3-dehydroquinate a 2-methyladenine 2503 2'-deoxyguanosine PPP a nucleoside 5'- BM400_RS21345 oligosyltrehalose ser D-glucopyranose i [+ 2 isozymes] (quinone) subunit D: 6 benzoquinol methylase L-glutamate-5- a proteinogenic apyrimidinic site) lyase: [+ 2 isozymes] [+ 2 isozymes] glycerol 3- nucleoside- [tRNA ] 5'-deoxyadenosine met N -(γ-glutamyl)- DNA hydroxytetracosanoyl- 1-palmitoyl-[+ 3 isozymes] in reverse hydroxyhexacos- FabZ: fabZ FabZ: fabZ dehydratase: in 23S rRNA an electron- + monophosphate trehalohydrolase: UDP-N-acetyl- a tRNA ser NAD BM400_RS12470 UbiE: BM400_RS15625 semialdehyde amino acid BM400_RS05295 an aldehyde butan-1-al a (2E)-icos- ITP RS13145 phosphate diphosphate GDP ala BM400_RS15585 L-lysine crosslink [acp] 2-myristoyl orientation 7-enoyl-[acp] biotin-carboxyl carrier α glucokinase: transfer quinol + an apyrimidinic a (2E)-but- kinase: bifunctional (p)ppGpp treZ Glu -D-muramate menadiol NAD menaquinol-12 2-enoyl-[acp] acyltransferase: protein assembly pyrophosphokinase: glk 3-oxoadipate site in DNA phosphatidate RS02910 2-enoyl-[acp] plsY BM400_RS21345 BM400_RS00200 synthetase/guanosine- 3-dehydroshikimate α,α-trehalose UDP-N- D-glucopyranose a [biotin carboxyl- 3',5'-bis(diphosphate) 3'- glutamate crotonyl-[acyl- acetylmuramate-- 6-phosphate a 1-acyl-sn carrier protein]-L-lysine pyrophosphohydrolase: racemase: shikimate shikimate decaprenyl-diphospho-N- UDP-N-acetyl- luteolin 7-O-[β-D- 1915 a (5Z)-3- an (11Z)-3- a (3R,7Z)-3- RS02500 carrier-protein] proline-- 1-palmitoylglycerol a pseudouridine a pectate an L-seryl- 2-phospho- 5'-chloro-5'- 1-palmitoylglycerol Secondary Metabolite Biosynthesis murI L-alanine ligase: dehydrogenase: dehydrogenase: pro glucose-6- α 18-hydroxystearate β butan-1-ol 5-MTR-1-P -glycerol 3- biotin--[acetyl-CoA- BM400_RS00200 tRNA ligase: acetylmuramoyl-pentapeptide -D-glucosamine glucosyluronate-(1,2)- - a palmitoyl-[acp] in 23S rRNA selenophosphate sec D-glycerate deoxyadenosine acyl-carrier protein a dodecanoyl-[acp] oxotetracos- oxooctadec- hydroxy-hexadec- reductase: BM400_RS17635 3-phosphate exo-poly-alpha-D- [tRNA ] 3-phosphate phosphate carboxylase] ligase: BM400_RS15585 BM400_RS15585 phosphate undecaprenyldiphospho- long-chain fatty D-glucosiduronate]-4'- 23S rRNA 2,3-bisphosphoglycerate- purine-nucleoside 5-enoyl-[acp] 11-enoyl-[acp] NAD(P)- 7-enoyl-[acp] S-methyl-5- BM400_RS02475 GDP BM400_RS08350 an L-prolyl- 1-acyl-sn-glycerol- L-seryl-tRNA 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-hydroxyacyl- RS18535 preQ biosynthesis D-glt UDP-N-acetyl-α-D- isomerase: muramoylpentapeptide beta-N- acid--CoA ligase: β galacturonosidase: phosphorylase: ACP S- enoyl-ACP 1-acyl-sn-glycerol- BM400_RS06090 0 Pro O- -D-glucosiduronatebeta-glucuronidase: 3-phosphate (pseudouridine(1915)- selenium independent 3-phosphate reductase: reductase: dependent alcohol thioribose-1- 2,3,4-saturated fatty myo-inositol shikimate [tRNA ] [acyl-carrier- 3-phosphate a [biotin carboxyl- muramoyl-L-alanine BM400_RS12080 UDP-glucose UDP-glucose acetylglucosaminyltransferase: BM400_RS16050 N(3))-methyltransferase BM400_RS08495 phosphoglycerate BM400_RS08315 malonyltransferase: reductase: dehydrogenase: biosynthesis a tRNA Pro BM400_RS10460 acyltransferase: transferase: acyltransferase: BM400_RS02475 BM400_RS02475 protein] phosphate RS03835 acyl-[acp]:NAD+ carrier protein]-N UDP-glucose-- 4-epimerase UDP-glucose-- 4-epimerase murG exo-poly-alpha-D- 5-chloro-5- BM400_RS04720 BM400_RS15255 acyltransferase: BM400_RS03325 3 RlmH: BM400_RS03800 BM400_RS01400 mutase: BM400_RS03325 BM400_RS04005 isomerase: 6 shikimate kinase: decaprenyl-pyrophosphoryl- 18-hydroxystearoyl- beta-glucuronidase: an N - an L- a (3R,5Z)-3-[+ 7 isozymes] a (3R,11Z)-3-[+ 7 isozymes] dehydratase oxidoreductase: -biotinyl-L-lysine D-glucopyranose UDP-N- F6P hexose-1-phosphate GalE: galE hexose-1-phosphate GalE: galE AMP diphosphate galacturonosidase: adenine deoxyribose a (2E)-dodec- BM400_RS08275 GTP lipid IV biosynthesis CoA 1915 BM400_RS14215 [+ 2 isozymes] FabZ: fabZ mtnA BM400_RS15255 acetylmuramoyl- A BM400_RS09720 UDP (N-acetylglucosamine)-N- luteolinBM400_RS04310 7-O-β- [+ 3 isozymes] methylpseudouridine selenocysteinyl- a malonyl-[acp] 1-palmitoyl-2-[+ 3 isozymes] hydroxytetracos- hydroxyoctadec- a (2E,7Z)- 5-(methylthio) 6-phosphate uridylyltransferase: UDP-glucose uridylyltransferase: UDP-glucose β BM400_RS01855 3-phospho- 1-phosphate 2-enoyl-[acp] RS13160 [+ 3 isozymes] GTP inositol-3- acetylmuramyl-(pentapeptide) -D-glucuronate dipalmitoyl in 23S rRNA [tRNA sec ] butan-1-al ribulose 1- L-alanine-- BM400_RS08450 D-diglucuronide acyl-carrier protein α-D,α-D- D-glycerate palmitoleoyl 5-enoyl-[acp] 11-enoyl-[acp] hexadeca-2,7- a 1,2-diacyl- cyclohydrolase phosphate a (3R)-3- shikimate 3- BM400_RS08450 4-epimerase 4-epimerase phosphatidate a pectate a butanoyl-[acp] D-glutamate UDP-N-acetyl- phenylalanine- α-D-glucopyranose α-D-glucopyranose phosphatidate dienoyl-[acp] phosphate RS06575 sn-glycerol 7,8- hydroxytetradecanoyl- phosphate GalE: galE α GalE: galE digalacturonate a [biotin carboxyl- I FolE: folE synthase: α-D-glucosamine UDP-α-D-galactose UDP- -D-galactose dihydroneopterin ligase: murD -tRNA ligase β-D-fructose 1,6- 1-phosphate 1-phosphate 3-phosphate carrier-protein dimer]- BM400_RS15195 [acp] UDP-N- β-ketohexanoyl- 3-phosphoshikimate 1- subunit phosphatidate 6 3'-triphosphate bisphosphate N -biotinyl-L-lysine acetylglucosamine an odd numbered 34 a (6Z)-3- a [lipoyl-carrier a (3R,5Z)-3- (3R,5S)-3- RS13860 [acp] synthase: Ins(3)P UDP-N-acetyl- carboxyvinyltransferase: beta: pheT alpha-D-glucose alpha-D-glucose a single (15Z)- a cis- 1-palmitoylglycerol a guanine a ribonucleoside 4-phosphooxy- 1-palmitoylglycerol cytidylyltransferase: 6-carboxytetrahydropterin acyltransferase: a purine queuine D-ribulose 5-phosphate roseoflavin 5,6-dihydrouracil acetoacetyl-CoA oxooctadec- protein]-N 6 -[(R) BM400_RS13030 acetyl-CoA acetyl-CoA meso-diaminopimelate α-D-muramoyl-L- aroA phosphate-specific phosphate-specific stranded DNA tetracosenoate straight chain arsenate in tRNA ATP 5'-monophosphate L-threonine hydroxy-tetradec- hydroxy-1- BM400_RS11220 synthase: UDP-3-O-[(3R)-3- phenylalanine- vaccenoyl-[acp] 3-phosphate 3-phosphate RS07585 carboxylase carboxylase inositol BM400_RS00275 5-enolpyruvoyl- glucose and glucose-1-phosphate degradation exodeoxyribonuclease long-chain fatty 2,3,4-saturated ribonucleoside tRNA guanosine(34) 3,4-dihydroxy- 5'-phosphate 4-hydroxythreonine- 3-hydroxybutyryl- 6-enoyl-[acp]3-oxoacyl-ACP -dihydrolipoyl]- 5-enoyl-[acp] pyrroline-5- 3-oxoacyl- alanyl-D-glutamate phosphoglucomutase: phosphoglucomutase: 1-acyl-sn-glycerol- purine-nucleoside bifunctional 1-acyl-sn-glycerol- NAD-dependent 3-hydroxyacyl- a CDP- BM400_RS08400 hydroxymyristoyl]-N- shikimate 3- -tRNA ligase VII small subunit: xseB acid--CoA ligase: long-chain fatty transglycosylase 2-butanone- bifunctional riboflavin 4-phosphate CoA L-lysine carboxyltransferase biotin monophosphatase: phe BM400_RS08160 BM400_RS08160 fatty acid 3-phosphate metallophosphatase/ 3-phosphate dihydropyrimidine reductase: [acyl-carrier- carboxylatepyrroline-5- [acyl-carrier- acetyl-α-D-glucosamine subunit alpha: acid--CoA ligase: phosphorylase: dihydrolipoyl diacylglycerol subunit alpha: carboxylase 6-carboxytetrahydropterin BM400_RS09810 phosphate α-D-glucopyranose exodeoxyribonuclease BM400_RS16050 Tgt: 4-phosphate kinase/FMN dehydrogenase dehydrogenase: BM400_RS02475 carboxylate protein] UDP-N- triose-phosphate L-arabinose an odd numbered acyltransferase: BM400_RS08315 5'-nucleotidase: acyltransferase: dehydrogenase dehydrogenase: protein] RS08145 synthase QueD: queD UDP-3-O-acyl-N- BM400_RS00945 an L-phenylalanyl- D-glucopyranose D-glucopyranose 1-phosphate BM400_RS16050 BM400_RS03035 synthase: ribB adenylyltransferase: PdxA: pdxA BM400_RS07560 BM400_RS13990 subunit: accC acetylmuramoyl- chorismate VII large subunit: xseA (Z)-15- BM400_RS03325 BM400_RS07335 3-amino-1- BM400_RS03325 subunit PreA: (S)-3- [+ 7 isozymes] dehydratase reductase: reductase: myo-inositol acetylglucosamine Phe isomerase: degradation I 6-phosphate AMP diphosphate straight chain ribose-1-arsenate a purine base a (3R,6Z)-3- a [lipoyl-carrierlpdA 6-carboxy-5,6,7,8- synthase: [tRNA ] 6-phosphate a single-stranded a ribonucleoside diphosphate AMP 34 1-deoxy-L-glycero- BM400_RS07740 proC FliF fabG acetyl-CoA acetyl-CoA L-alanyl-D- Phe BM400_RS17325 tetracosenoyl-CoA 2,3,4-saturated [+ 3 isozymes] a queuosine formate roseoflavin adenine a ribonucleoside hydroxyacetone [+ 3 isozymes] BM400_RS15875 hydroxybutanoyl- hydroxyoctadec- 6 FabZ: fabZ deacetylase: a tRNA D-glyceraldehyde oligodeoxyribonucleotide 5'-monophosphate 1-palmitoyl-2- guanine tetrulose 4-phosphate 1-palmitoyl-2- protein]-N - a (2E,5Z)- trans-4-hydroxy- tetrahydropterin glutamate--2, 6- BM400_RS15670 DHAP L-arabinopyranose in tRNA dinucleotide 1-phosphate uracil CoA carboxylase carboxylase BM400_RS03110 3-phosphate fatty acyl CoA acyl-carrier protein cis-vaccenoyl cis-vaccenoyl 6-enoyl-[acp] lipoyl-L-lysine tetradeca-2,5- L-proline a 3-oxohexanoyl- gondoate biosynthesis 7-carboxy-7- diaminopimelate L-arabinose alpha-D-glucose carboxyltransferase biotin UDP-3-O-(3- chorismate phosphatidate phosphatidate dienoyl-[acp] [acp] D-ala glyceraldehyde- phosphate-specific RS16575 (anaerobic) subunit beta: carboxylase deazaguanine ligase: hydroxymyristoyl) isomerase: D-glucopyranose 3-phosphate ribose phosphorylation phosphoglucomutase: FtsW 3-oxoacyl-ACP BM400_RS03790 subunit: accC synthase: BM400_RS09530 -α-D-glucosamine BM400_RS07975 xylose glucokinase: D-alanine--D- dehydrogenase: an [amino group carrier BM400_RS19390 methionine-- L-ribulose BM400_RS08160 quinoprotein a 2-methyl 1-cis- a [DNA]-3'- a 5'-phospho- D-arabinofuranose 3-carboxy- a (3R,6Z)-3- reductase: a malonyl-[acp] an oleoyl-[acp] a [carboxyl-carrier UDP-3-O-(3- met degradation I glk NaMN 5,6-dimethylbenzimidazole 18-hydroxyoleate a cis- NAD + hydantoin canavaninosuccinate a cis-delta11-3- D-mannitol digallate alanine ligase: gap branched 2,3,4- vaccenoylglycerol- a protein protein]-C-terminal-γ- 2,5-dihydro- an octanoyl-[acp] hydroxyoctadec- BM400_RS02475 protein dimer]-N 6 - 7-carboxy-7- UDP-N-acetyl-α-D- hydroxymyristoyl) tRNA ligase: β-D-ribopyranose glucose vaccenoyl-[acp] hydroxyl [DNA] oxaloacetate ITP 5-phosphate oxo-C30:1-[acp] (11Z)-3-oxo- BM400_RS02620 an L-methionyl- ribulokinase: nicotinate-nucleotide-- long-chain fatty DNA dihydropyrimidinase: argininosuccinate (L-glutamyl)-L-glutamate NAD(P)- muramoyl-L-alanyl- BM400_RS09850 D-ribose pyranase: D-xylopyranose dehydrogenase: saturated fattylong-chain acid fatty 1-acyl-sn-glycerol-3-phosphate D-alanyl-D-alanine- 3-deoxy-8- 5-oxofuran- 3-oxoacyl-ACP 6-enoyl-[acp]3-hydroxyacyl- tannase/feruloyl [+ 7 isozymes] icos-11-enoyl- carboxybiotinyl-L-lysine deazaguanine glucosamine N- phosphoenolpyruvate enoyl-ACP RS02960 [elongator 13-DPG BM400_RS08435 D-glucopyranose dimethylbenzimidazole acid--CoA ligase: ligase hydA lyase: argH phosphooctulonate 2-acetate dependent alcohol esterase family a (3R)-3- γ-D-glutamyl-meso- acyltransferase: BM400_RS18925 xylose BM400_RS01765 acid--CoA ligase: 3-phosphate carboxypeptidase/ acetylglutamate 3-carboxymuconate reductase: [acyl-carrier- RS15470 [acp] synthase: 7-cyano-7- D-alanyl-D-alanine elongator tRNA Met ] phosphoribosyltransferase: BM400_RS16050 D: ligD carboxykinase (GTP) reductase: dehydrogenase: 2,6-diaminopimelate β-D-ribofuranose L-ribulose 5- isomerase: 6-phosphate BM400_RS16050 acyltransferase: endopeptidase AmpH: hydantoinase: argininosuccinate synthase: kinase: argB BM400_RS02475 protein] alpha/beta hydroxyhexanoyl- BM400_RS13030 deazaguanine BM400_RS09965 tRNA Met a 2-methyl : BM400_RS08080 cyclase: BM400_RS15255 an (11Z)-3-oxo- phosphoglycerate phosphate D-glucono-1,5-lactone cobT BM400_RS02505 lyase: argH BM400_RS12745 BM400_RS04005 hydrolase: [acp] xylA 18-hydroxyoleoyl- branched BM400_RS03325 BM400_RS04455 phosphoenol an [amino group carrier BM400_RS19685 a cis-delta11-3-[+ 7 isozymes] dehydratase synthase UDP-3-O-(3- kinase: pgk α-ribazole AMP diphosphate NMN AMP [DNA] IDP a (2E)-oct- 3-hydroxyacyl- icos-11-enoyl-[acp] UDP-N- D-xylulose nicotinate CoA AMP diphosphate pyruvate fumarate L-canavanine protein]-C-terminal- 3-carboxy-cis [+ 2 isozymes] FabZ: fabZ BM400_RS17255 a sugar RS10405 a sugar phosphatidylethanolamine QueC: queC hydroxymyristoyl) L-ribulose-5- 2,3,4-saturated [+ 3 isozymes]1,2-dicis- a peptide a peptide N-carbamoylglycine KDO-8P hydroxyC30:1- aldehydo- a (2E,6Z)- 5'-phosphate ,cis-muconate 2-enoyl-[acp] [acyl-carrier- 3-oxoacyl-[acyl- acetylmuramoyl- 3-phospho- phosphate fatty acyl-CoA γ-(5-phospho-L- [acp] gallate biosynthesis I glucosamine N- xylulokinase: acyl-carrier protein vaccenoyl- D-mannose octadecadienoyl- RS05430 protein] carrier-protein] preQ tripeptide--D-alanyl- D-glycerate 4-epimerase D-mannose degradation glutamyl)-L-glutamate 0 α phosphatidate [acp] a sugar RS04985 a sugar acyltransferase: Lys -D-ribofuranose xylB dehydratase D- alanine ligase: a tRNA reductase: fabG a CDP-diacylglycerol lpxD lysine--tRNA ligase: AraD: araD D-gluconate FabZ: fabZ BM400_RS09535 ribokinase: D-xylulose D-mannopyranose [+ 7 isozymes] CDP-diacylglycerol--serine UDP-2-N,3-O-bis[(3R)- BM400_RS12385 D-xylulose an L-lysyl- 5-phosphate a dolichyl β- 1-stearoyl- a [pyruvate dehydrogenase a (9Z)-3- a (3R,9Z)-3- a sugar RS19895 a sugar O-phosphatidyltransferase: rbsK 5-phosphate 6-phosphate a very-long- an acyl-[acyl- 1-myristoylglycerol pyridoxamine a cis-delta21-3- 3-oxo- a (2E)-hex- a (3R,11Z)-3-hydroxy- 3-hydroxytetradecanoyl]- [tRNA Lys ] mannose-6- 16-hydroxypalmitate oleate carbamoyl a purine 2'- E2 protein] N 6 - roseoflavin RS15200 UDP-N-acetyl-α-D- 2-phospho- chain fatty acid D-mannosyl a [protein] Ser/Thr sn-glycerol asp a decanoyl-[acp] oxooctacos- hydroxyhexadec- icosatrienoyl-CoA pssA α-D-glucosamine α-D-ribose phosphate carrier protein] phosphate GTP 3-phosphate 5'-phosphate oxo-C40:1-[acp] 2-enoyl-[acp] icos-11-enoyl-[acp] a 3-sn-phosphatidyl- muramoyl-L-alanyl- lys D-glycerate long-chain fatty long-chain fatty phosphate 3-phosphate long-chain fatty deoxyribonucleoside dihydrolipoyl-L-lysine bifunctional riboflavin pyridoxamine 5'- 9-enoyl-[acp] 9-enoyl-[acp] 3-oxoacyl- dolichyl-phosphate- 1-acyl-sn-glycerol- aspartate 1-acyl-sn-glycerol- 3-oxoacyl-ACP 3-oxoacyl-ACP 3-hydroxyacyl- a sugar RS08480 a sugar 5-phosphate isomerase: acid--CoA ligase: acid--CoA ligase: acid--CoA ligase: purine-nucleoside GTP dihydrolipoyl kinase/FMN enoyl-ACP hexanoyl-[acyl- 3-hydroxyacyl- L-serine Carbohydrate Biosynthesis γ-D-glutamyl-meso- phosphopyruvate mannose--protein 3-phosphate carbamoyltransferase 3-phosphate phosphate oxidase: reductase: reductase: [acyl-carrier- [acyl-carrier- BM400_RS12030 phosphorylase: cyclohydrolase dehydrogenase: reductase: phosphatidylserine 2,6-diaminopimeloyl- di-trans,octa-cis- BM400_RS16050 BM400_RS16050 BM400_RS16050 adenylyltransferase: BM400_RS13620 protein] carrier-protein] [acyl-carrier- hydratase: mannosyltransferase: acyltransferase: catalytic subunit: BM400_RS08315 2,5-diamino-6- acyltransferase: BM400_RS02475 BM400_RS02475 protein] undecaprenyl phosphate F6P 2-deoxy-α- II: ribA lpdA BM400_RS07740 BM400_RS15255 reductase: L-fucose FucP L-fucose reductase: protein] decarboxylase: D-alanyl-D-alanine lipid X BM400_RS14965 16-hydroxypalmitoyl- a very-long-chain α BM400_RS19015 BM400_RS08275 BM400_RS02870 BM400_RS03325 [+ 2 isozymes] [+ 7 isozymes] [+ 7 isozymes] dehydratase RS12095 UDP-N-acetyl-D- AMP diphosphate AMP diphosphate a 3-O-( -D- diphosphate AMP oleoyl-CoA D-ribose 1- a purine base (5-phospho-D- a [pyruvate dehydrogenase roseoflavin a cis-delta21-3- a cis-delta9-3- BM400_RS02475 BM400_RS16305 dTDP-L-rhamnose GDP-L-fucose histidine-- a dolichyl N-carbamoyl- formate a (2E)-dec- fabG dehydratase glucosamine biosynthesis I his phosphoenol CoA fatty acyl-CoA mannosyl)-(Ser/ [+ 3a isozymes]1-stearoyl 2- ribosylamino) E2 protein] N 6 -lipoyl-L-lysine [+ 3 isozymes] PLP hydroxyC40:1- hydroxyC28:1- a (2E,9Z)-FabZ: fabZ biosynthesis I biosynthesis I (from lipid-A-disaccharide tRNA ligase: phosphate L-aspartate phosphate 5'-phosphate dimyristoyl 2-enoyl-[acp] 3R-hydroxy- 2,3,4-saturated fatty FabZ: fabZ an L-1- pyruvate Thr)-[protein] acyl-carrier protein acyl-sn-glycerol pyrimidin-4(3H)-one [acp] [acp] hexadeca-2,9- L-fucose FucP L-fucose D-glucopyranose GDP-D-mannose) synthase: BM400_RS05750 phosphatidate icosatrienoyl-CoA acyl-[acp]:NAD+ phosphatidylethanolamine α an L-histidyl- a (2E,11Z)-icosa- 6-phosphate -D-glucopyranose BM400_RS13455 pyruvate Amino Acid Degradation 3-phosphate dienoyl-[acp] GDP-α-D-mannose undecaprenyldiphospho- [tRNA His ] oxidoreductase: 2,11-dienoyl-[acp] glucose-6- 1-phosphate kinase: pyk RS08915 N-acetylmuramoyl-L- His a cation RS06490 a cation BM400_RS15255 phosphate glucose-1-phosphate GDP-mannose lipid A disaccharide a tRNA (1R,6R)-6-hydroxy-2- 5,6- (2E,11Z)-icosa- thymidylyltransferase: 4,6-dehydratase: alanyl-γ-D-glutamyl-meso L-proline degradation 2-amino-6-[1-hydroxyethyl]- a 3-methyl- 7,8- a 1-phosphatidyl- (1S,2R)-1- a (3R,9Z)-3- isomerase: pyruvate L-serine degradation 7-hydroxylaurate quinoxaline-2- a [protein]-L-glutamine serotonin (S)-dihydroorotate a cis-delta13-3- 2,11-dienoyl- gmd -2,6-diaminopimeloyl- glycine cleavage L-threonine acyl-carrier protein branched 2,3,4- dihydroneopterin 3'-dephospho- succinylcyclohexa-2,4- C-(indol-3- dihydrothymine his hydroxy-octadec- ala a hexanoyl-[acp] BM400_RS12080 rfbA GDP-4-dehydro- tetraacyldisaccharide 7-methyl-7,8-dihydropterin carboxyl adenylate ATP ATP H O 1D-myo-inositol ser oxo-C32:1-[acp] a cation RS13585 a cation dTDP-α-D-glucose degradation II long-chain fatty transglutaminase: CoA 2 diene-1-carboxylate NAD-dependent [acp] reductase: F6P D-alanyl-D-alanine 4'-kinase: lpxK 2-amino-4-hydroxy-6- acyl carrier protein: saturated fattylong-chain acid fatty 3'-triphosphate6-pyruvoyl phosphatidylinositol yl)glycerol 3-oxoacyl-ACP 9-enoyl-[acp]3-hydroxyacyl- α-D-rhamnose a [glycine- dephospho- ATPase: dihydroorotase: L-histidine N(alpha) alanine RS15345 BM400_RS02475 undecaprenyldiphospho- pro ser acid--CoA ligase: BM400_RS13735 o-succinylbenzoate 3-phosphate tryptophan dihydropyrimidine reductase: 3-oxoacyl- dTDP-glucose 4,6- glycine-- L-cysteine hydroxymethyldihydropteridine BM400_RS09185 acid--CoA ligase: tetrahydrobiopterin CoA kinase: kinase: [acyl-carrier- GDP-L-fucose lipid IV proline cleavage complex BM400_RS16050 BM400_RS07550 synthase BM400_RS02875 dehydrogenase -methyltransferase: racemase: a cation RS00700 a cation glutamine-- dehydratase: rfbB muramoylpentapeptide beta-N- A threonine/serine degradation II thr diphosphokinase: folK [+ 2 isozymes] BM400_RS16050 transglutaminase: synthase: synthase: menC BM400_RS03545 BM400_RS02475 protein] [acyl-carrier- synthase: tRNA ligase H protein] N 6 - glycine a 3-methyl- BM400_RS04655 [+ 6 isozymes] egtD alr a gondoyl-[acp] fructose-6- acetylglucosaminyltransferase: dehydrogenase: L-threonine 3- [1-(2-amino-7-methyl-4-oxo- a quinoxaline-2- BM400_RS13740 a 1-phosphatidyl- subunit subunit PreA: protein] dTDP-4-dehydro-6- subunit alpha: dehydratase: 7-hydroxylauroyl- 6 BM400_RS08405 [+ 7 isozymes] dehydratase BM400_RS17070 lipoyl-L-lysine dehydrogenase branched a [protein] N -[(5-hydroxy-1H (6R)-6-pyruvoyl- + + N-carbamoyl- a cis-delta13-3- phosphate murG BM400_RS11050 dehydrogenase: 7,8-dihydro-3H-pteridin- AMP diphosphate AMP carboxyl-[aryl- diphosphate AMP ADP coenzyme A H H phosphate ADP 2-succinylbenzoate 1D-myo-inositol beta: trpB BM400_RS15875 reductase: deoxy-α-D-glucopyranose BM400_RS09865 Respiration (S)-1-pyrroline- BM400_RS18935 cys CoA 2,3,4-saturated PPP 5,6,7,8- D-glyceraldehyde L-aspartate hydroxyC32:1- hercynine a (2E,9Z)-FabZ: fabZ D-ala a cation RS15635 a cation lipid II (meso subunit 2: carrier protein] -indol-3-yl)ethyl]-L-glutamine i trp transaminase GDP-β-L-fucose 5-carboxylate dihydrolipoyl BM400_RS12235 6-yl)]ethyl diphosphate 4-phosphate thymine RS12665 fabG dTDP-4- glycine--tRNA L-serine cystathionine BM400_RS01730 L-2-amino-3- fatty acyl-CoA tetrahydropterin 3-phosphate [acp] octadeca-2,9- (isomerizing) diaminopimelate gly dehydrogenase: β-ketooctanoyl- dehydrorhamnose ligase subunit beta: 2-oxoglutarate decarboxylation to succinyl-CoA ammonia-lyase: gamma-lyase: oxobutanoate dienoyl-[acp] : glmS containing) lpdA a cation RS05105 a cation 3,5-epimerase: rfbC BM400_RS20495 [acp] synthase: BM400_RS09870 2-aminoprop- 2-aminoprop-BM400_RS18960 glycine C- D-glucosamine a glycyl-[tRNA Gly ] a [2-oxoglutarate BM400_RS13030 dTDP-4-dehydro- a [glycine- 2-enoate 2-enoate a [glycine-cleavage acetyltransferase: 5-dehydro-4-deoxy- a supercoiled a (3R,11Z)-3- 6-phosphate β Gly dehydrogenase E2 L-glutamate-5- α 2+ + 2+ 2+ -L-rhamnose cleavage complex 6 dioscin p-nitrophenyl- -L-rhamnopyranoside protoporphyrin IX Mg a nucleoside CMP-Kdo lipid IV NAD NADPH a cis-delta15-3- a nucleoside Mg RS21300 Mg RS01100 a tRNA 6 2-methylbutanoate phytenate a purine A (S)-5-hydroxyisourate a 3-oxooctanoyl- 6 complex H protein] N - BM400_RS02885 D-glucuronate duplex DNA hydroxyoctadec- pro phosphoglucosamine protein] N -lipoyl-L-lysine semialdehyde H protein] N - triphosphate GTP H O oxo-C34:1-[acp] diphosphate dTDP-4- aminomethyldihydrolipoyl- alpha-L-rhamnosidase: alpha-L-rhamnosidase: acetate- long-chain fatty magnesium chelatase: ribonucleoside 2 3-deoxy-D-manno- 5-dehydro-4-deoxy- NAD(P) ATP-dependent [acp] UDP-α-D- 2-oxoglutarate 3-oxoacyl-ACP nucleoside- 11-enoyl-[acp]3-hydroxyacyl- pyrroline-5- mutase: glmM dehydrorhamnose L-glutamate dihydrolipoyl- gly BM400_RS14040 purine-nucleoside nucleoside triphosphate GTPase Era: octulosonic acid D-glucuronate hydroxyisourate dehydrogenase L-lysine BM400_RS14040 -CoA acid--CoA ligase: BM400_RS09590 transhydrogenase DNA helicase Rep: reductase: diphosphate Mg 2+ RS13575 Mg 2+ 3-oxoacyl-ACP galactose L-lysine phosphorylase: pyrophosphohydrolase: [acyl-carrier- carboxylate phosphoglucosamine reductase: rfbD gamma- alpha-L-rhamnosidase: ligase: acs BM400_RS16050 BM400_RS07315 transferase: isomerase: subunit beta: hydrolase: uraH BM400_RS05790 biosynthesis E1 component: 2-iminopropanoate 2-iminopropanoate alpha-L-rhamnosidase: magnesium chelatase: BM400_RS02475 kinase: protein] reductase: reductase: mutase: semialdehyde BM400_RS08315 BM400_RS21120 [+ 2 isozymes] BM400_RS19465 BM400_RS17375 RS14310 dTDP-β-L-rhamnose methionine-- BM400_RS19975 BM400_RS04160 BM400_RS04160 BM400_RS16460 α-D-ribose- BM400_RS07185 (S)-2-oxo-4- [+ 3 isozymes] BM400_RS21345 BM400_RS02475 UDP-α-D-glucose met 2-methylbutanoyl- α-Kdo-(2->6) a cis-delta15-3-[+ 7 isozymes] dehydratase proC + + BM400_RS07690 2-oxoglutarate dehydrogenase: β AMP diphosphate diphosphate AMP phytenoyl-CoA a purine base a nucleoside 5'- phosphate GDP H + CMP 3-deoxy-D-glycero- hydroxy-4-carboxy- a single a nucleoside (S)-1-pyrroline- K KdpF K tRNA ligase: 2-oxoglutarate aminomethyltransferase: 3-O- -D-glucosyl-diosgenin L-rhamnopyranose β-L-rhamnopyranose 4-nitrophenol CoA Mg-protoporphyrin 1-phosphate -lipid IV [+ 2 isozymes] FabZ: fabZ [+ 7 isozymes] D-glucosamine UDP-glucose pruA monophosphate A 2,5-hexodiulosonate stranded DNA hydroxyC34:1- a (2E,11Z)- BM400_RS09850 dehydrogenase + 5-ureidoimidazoline triphosphate 5-carboxylate a (3R)-3- an L-methionyl- dehydrogenase: L-glutamine lpdA NADP NADH [acp] octadeca-2,11- 1-phosphate 4-epimerase E1 component: L-phenylalanine degradation I (aerobic) + + 2+ 2+ [initiator tRNA Met ] BM400_RS03480 K KdpB K Mo RS16105 Mo hydroxyoctanoyl- GalE: galE Glu degradation I dienoyl-[acp] UDP-N- initiator tRNA Met BM400_RS19975 pyruvate pyruvate [acp] a [2-oxoglutarate (6R)-4a-hydroxy- acetylglucosamine UDP-α-D-glucose UDP-glucose a [2-oxoglutarate[+ 2 isozymes] 2+ 2+ 3-hydroxyacyl- dehydrogenase + + Co RS16430 Co biosynthesis I 4-epimerase dehydrogenase E2 protein] gln tetrahydrobiopterin 4a-hydroxytetrahydrobiopterin β 1-deoxy-L- K RS02580 K [acyl-carrier- diphosphorylase/ 6 (7R)-7-(4-carboxybutanamido) 6-(hydroxymethyl) + luteolin 7-O- - a [protein]- an organic (7Z)- a [protein]-L- a cis-delta19-3- an organic (S)-1-pyrroline- 6 E2 protein] N -S- asparagine dehydratase: α-linolenate decanoate hydrogencarbonate H a uridine in tRNA carbonic acid glycerol histidinol glucosamine-1- GalE: galE N -dihydrolipoyl-L-lysine cephalosporanate -7,8-dihydropterin D-glucuronide L-cysteine hydroperoxide ARP glycero-tetrulose hexadecenoyl-CoA proline (ω = 180) hydroperoxide 5-carboxylate protein] D-glucopyranose α succinyldihydrolipoyl-L-lysine oxo-C38:1-[acp] + + UDP- -D-galactose synthetase B: BM400_RS12770 glutaryl-7-ACA acylase: long-chain fatty long-chain fatty carbonic anhydrase: beta-glucuronidase: peroxiredoxin: 4-phosphate carbonic anhydrase: NAD(P)- acyl-CoA peptidylprolyl peroxiredoxin: L-glutamate Na RS18395 Na dehydratase phosphate N- 6-phosphate 2-amino-4-hydroxy-6- 6,7-dimethyl-8- tRNA dihydrouridine 3-oxoacyl-ACP histidinol K + RS02570 K + L-alanine BM400_RS10265 dependent alcohol gamma- acetyltransferase: alpha-D-glucose BM400_RS08300 hydroxymethyldihydropteridine acid--CoA ligase: acid--CoA ligase: BM400_RS18355 BM400_RS10460 BM400_RS00265 synthase DusB: BM400_RS18355 dehydrogenase: isomerase: reductase: BM400_RS00265 dehydrogenase: FabZ: fabZ degradation IV ribityllumazine phosphate-specific [+ 7 isozymes] glutaryl-7-ACA acylase: BM400_RS16050 BM400_RS16050 carbonic anhydrase: beta-glucuronidase: peroxiredoxin: carbonic anhydrase: dehydrogenase: BM400_RS17225 BM400_RS09745 peroxiredoxin: semialdehyde glmU diphosphokinase: folK synthase: BM400_RS02300 BM400_RS02475 hisD a (2E)-oct- phosphoglucomutase: Glu (6R)-L-erythro-5,6,7,8- L-erythro-7,8- BM400_RS20985 (7,8-dihydropterin- BM400_RS01660 BM400_RS04310 BM400_RS04715 BM400_RS01660 BM400_RS04005 [+ 2 isozymes] [+ 4 isozymes] BM400_RS04715 dehydrogenase: nitrate RS12865 nitrate RS18680 N-acetyl-α-D- BM400_RS19315 a 5,6-dihydrouridine [+ 7 isozymes] ala AMP diphosphate α-linolenoyl-CoA diphosphate AMP decanoyl-CoA an intra- (2E,7Z)- a [protein]-L- a cis-delta19-3- pruA 2-enoyl-[acp] glucosamine α BM400_RS08160 2-oxoglutarate tetrahydrobiopterin dihydrobiopterin glutarate (7R)-7 aminocephalosporanate 6-yl)methyl H O CO β-D-glucuronate luteolin an alcohol 6,7-dimethyl-8-(1- CO H O [+ 2 isozymes] an alcohol his -D-glucopyranose 2 2 in tRNA 2 2 ω hydroxyC38:1- PRPP biosynthesis I diphosphate protein disulfide D-ribityl)lumazine hexadecenoyl-CoA proline ( = 0) octanoyl-[acyl- 1-phosphate 1-phosphate dehydrogenase alanine L-glyceraldehyde [acp] Glu nitrate RS09380 nitrate E1 component: dehydrogenase: ald carrier-protein] UDP-N- UTP--glucose- D-ribose 5- BM400_RS19975 pyruvate RS16930 reductase: acetylglucosamine 1-phosphate phosphate Fatty Acid and Lipid Degradation BM400_RS02475 diphosphorylase/ phosphoribosylpyrophosphate 2-oxoglutarate uridylyltransferase: Carboxylate Degradation 10 3 a 3- (S)-2-oxo-4- ArsB synthetase: BM400_RS07905 L-ascorbate 4a-hydroxy-N - α,ω-9Z- an N -methyladenine an (S)-2- 5'-deoxy-5'- an apo-[LYS2 L- D-gluconate 2,3,4-saturated fatty glucosamine-1- galU dehydrogenase: (S)-methylmalonate-semialdehyde pristanate palmitoleoyl-CoA squalene a cis-delta17-3- phytol ethanol degradation II fatty acid β-oxidation I a protein halocarboxylate 2-aminoadipyl- coenzyme A 6-phosphate oxodocosanoyl- hydroxy-4-carboxy- phosphate N- PRPP BM400_RS03480 formyltetrahydrofolate octadecenedioate in DNA fluoroadenosine oxo-C36:1-[acp] acyl-[acp]:NAD+ methylmalonate- long-chain fatty long-chain fatty DNA-3- haloacid purine-nucleoside 6-phosphogluconate [acp] acyl-CoA squalene--hopene 5-ureidoimidazoline NAD(P)- catalase/ UDP-α-D-glucose (bacterial, aerobic) 4a-hydroxytetrahydrobiopterin endopeptidase La: lon carrier-protein] holo-ACP 3-oxoacyl-ACP 3-oxoacyl-ACP oxidoreductase: acetyltransferase: OHCU RS14120 a (3Z)-alk-3- semialdehyde dehydratase: acid--CoA ligase: acid--CoA ligase: methyladenine endopeptidase La: dehalogenase: phosphorylase: synthase: dehydrogenase reductase: dehydrogenase: cyclase: shc reductase: dependent alcohol peroxidase glmU L-ascorbate decarboxylase: BM400_RS15255 enoyl-CoA dehydrogenase (CoA BM400_RS16050 BM400_RS16050 glycosylase I: BM400_RS13610 BM400_RS08315 (decarboxylating): gnd BM400_RS17225 squalene--hopene dehydrogenase: HPI: katG BM400_RS12770 BM400_RS10605 a holo-[LYS2 L- acpS BM400_RS02475 BM400_RS02475 RS00690 UDP-N-acetyl- Pentose Phosphate Pathways acylating): mmsA ω-carboxy- BM400_RS15755 5-fluoro-5- uraD BM400_RS04005 an N 10 -formyl- [+ 4 isozymes] [+ 2 isozymes] [+ 7 isozymes] [+ 2 isozymes] cyclase: shc [+ 7 isozymes] [+ 2 isozymes] an octanoyl-[acp] α-D-glucosamine AMP diphosphate pristanoyl-CoA AMP diphosphate (9Z)-octadec- an apurinic site a peptide a peptide an (R)-2- deoxy-D-ribose adenine 2-aminoadipyl- 3',5'-ADP D-ribulose a (3R)-3- (2E,9Z)- a cis-delta17-3- L-dehydro- H + NADH hydrogencarbonate propanoyl-CoA 7,8-dihydrofolate 3-methyladenine a halide anion hop-22(29)-ene (S)-(+)-allantoin [+ 2 isozymes] acetaldehyde 9-enoyl-CoA within DNA hydroxyacid 1-phosphate carrier-protein] 5-phosphate hydroxydocosanoyl- hexadecenoyl-CoA hydroxyC36:1- RS04170 pentose phosphate pathway (non-oxidative branch) ascorbate phytenal 3-oxoacyl- Amino Acid Biosynthesis a (2E)-2- [acp] [acp] [acyl-carrier- enoyl-CoA D-ribulose RS15640 protein] a 2,3,4-saturated long-chain fatty L-histidine biosynthesis coenzyme A superpathway of branched chain amino acid biosynthesis L-tryptophan biosynthesis L-threonine 5-phosphate acid--CoA ligase: acyl-CoA a 3- reductase: L-lysine biosynthesis I L-arginine biosynthesis II (acetyl cycle) L-asparagine fatty acid 10 an L-methionyl- MoO - D-tagatofuranose (7Z)- (S)-4-amino-5- dehydroascorbate methylmalonate semialdehyde an N - L-rhamnulose 1-phosphate linoleate methyl red a colanic acid lipid A-core 2 an acyl- NaMN 3-keto-L-gulonate a dipeptide MeOH RS01875 fabG biosynthesis pyruvate fermentation BM400_RS16050 dehydrogenase: a 2,3,4- Met 1,6-bisphosphate coenzyme A oxodocosanoyl- tetradecenoyl-CoA thr oxopentanoate biosynthesis III (bicyclic form) formyltetrahydrofolate [initiator tRNA ] molybdopterin ATP carrier protein PRPP ribulose-phosphate ribose-5-phosphate BM400_RS17225 saturated (3R)-3- methylmalonate- bifunctional rhamnulose-1- long-chain fatty FMN-dependent O-antigen tagatose 1,6- bifunctional [acp] acyl-CoA 3-dehydro-L- membrane glutamate-1- catalase/ β pyruvate (tRNA-dependent) to acetate IV methionyl-tRNA cofactor holo-ACP 3-oxoacyl-ACP -ketodecanoyl- thr asp N-acetylglutamyl-phosphate gln chorismate 3-epimerase: isomerase RpiA: ligase domain- molybdenum cofactor L-threonine 3- L-homoserine [+ 2 isozymes] a 2,3,4- hydroxyacyl-CoA semialdehyde formyltransferase: phosphate aldolase/short- acid--CoA ligase: NADH- diphosphate synthase: metallophosphatase/ reductase: dehydrogenase: gulonate 2- dipeptidase: semialdehyde- peroxidase RS01910 [acp] synthase: ATP lysine-sensitive N-acetyl-gamma- BM400_RS02415 BM400_RS05965 a 2,3,4-saturated containing protein: guanylyltransferase: dehydrogenase: acetolactate asp pyruvate saturated (3S)-3- dehydrogenase (CoA BM400_RS15660 chain dehydrogenase: BM400_RS16050 azoreductase: aldolase: acpS 5'-nucleotidase: BM400_RS02475 BM400_RS17225 dehydrogenase: BM400_RS12655 2,1- HPI: katG BM400_RS13030 phosphoribosyltransferase: threonine/serine homoserine fatty acyl CoA an N-formyl- adenylyl BM400_RS12235 synthase aspartokinase 3: glutamyl-phosphate anthranilate synthase: hydroxyacyl-CoA acylating): mmsA BM400_RS08485 BM400_RS10625 BM400_RS06360 BM400_RS11325 BM400_RS09650 BM400_RS07335 [+ 2 isozymes] BM400_RS12265 [+ 2 isozymes] aminomutase: [+ 2 isozymes] RS06280 BM400_RS01605 kinase: thrB 2,3-dioxo- L-methionyl- a tetrahydrofolate acyl-carrier protein 3',5'-ADP β a (3R)-3-[+ 7 isozymes] dehydratase: BM400_RS20410 reductase: argC D-xylulose D-ribose 5- + AMP diphosphate linoleoyl-CoA N,N'-dimethyl-p- molybdenum D-glyceraldehyde -D- (2E,7Z)- 2,3-dioxo- a 3-oxodecanoyl- BM400_RS21150 3-hydroxyacyl-CoA met E. coli M a proteinogenic aminoacetone hemL small subunit: O-phospho- H NADH hydrogencarbonate propanoyl-CoA DHAP (S)-lactaldehyde anthranilate LPS DHAP formaldehyde 1-(5-phospho- BM400_RS18935 bifunctional glutamate 5-phosphate phosphate L-gulonate [initiator tRNA ] phenylenediamine cofactor 3-phosphate ribosylnicotinate hydroxydocosanoyl- tetradecenoyl-CoA L-gulonate [acp] BM400_RS17585 L-aspartyl-4-phosphate an L-aspartyl- L-homoserine dehydrogenase: amino acid 5-aminolevulinate β N-acetyltransferase/ 3-dehydro-L- [acp] RS07320 -D-ribosyl)-ATP threonine anthranilate [tRNA Asn ] BM400_RS17205 3-oxoacyl-ACP acetolactate amino-acid threonine synthase: gulonate 2- ammonia-lyase: aspartate- transketolase: tkt RS12950 reductase: synthase, acetyltransferase acetylglutamate anthranilate Asp-tRNA(Asn) BM400_RS10590 dehydrogenase: acetyl-CoA formate superpathway of acetate a 2,3,4-saturated acetyl-CoA C- a 2,3,4-saturated BM400_RS02650 semialdehyde 6-phospho a [protein]- BM400_RS02475 large subunit, kinase: argB /Glu-tRNA(Gln) BM400_RS12265 utilization and formation fatty acyl CoA acyltransferase: 3-oxoacyl-CoA phosphatidylglycerophosphate 2-phospho-4-(cytidine 5'- a peptide with all-trans- β-D-glucose ArgJ: BM400_RS12940 phosphoribosyltransferase: trpD [+ 3 isozymes] D-sedoheptulose D-glyceraldehyde quercitrin octanoate a peptide with a a (7Z)-3-oxo- cis-vaccenoyl-CoA D-threo-isocitrate π biosynthetic (2Z)-2-aminobut- dehydrogenase: Glu phosphate diphospho)-2-C-methyl-D-erythritol D-glucono- an N-terminal a PII protein UTP L-cystathionine MEP N -phospho- 6-phosphate ala [+ 7 isozymes] 1-(5-phospho-β- N-acetyl-L-glutamate N-acetyl-L-glutamate 5-semialdehyde amidotransferase BM400_RS17215 (1-octadecenoyl(9Z), 2-palmitoyl) leader sequence retinyl palmitate hexadec-7-enoyl-[acp] 2-enoate asd 7-phosphate 3-phosphate 3-keto-L-gulonate acetyltransferase 2-C-methyl-D-erythritol alpha-L-rhamnosidase: long-chain fatty 1,5-lactone carboxylesterase/ acyl-CoA isocitrate L-histidine inositol-3- RS07595 a (3R)-3- D-ribosyl)-AMP type: ilvB N-(5-phosphoribosyl)-anthranilate subunit GatB: thr acetate Xaa-L-prolineleucyl signal [protein-PII] cystathionine 3-oxoacyl-[acyl- 1-deoxy-D-xylulose- N-acetylornithine PlsX: 2,4-cyclodiphosphate phosphohistidine alanine hydroxydecanoyl- L-aspartate- BM400_RS04405 phosphatidylglycerophosphatase BM400_RS14040 acid--CoA ligase: 6-phosphogluconolactonase: aminopeptidase: peptidase I: lepB uridylyltransferase: gamma-lyase: lipase family carrier-protein] dehydrogenase: dehydrogenase 5-phosphate phosphate RS12315 phosphoribosyl- aminotransferase: L-alanine transaldolase: tal acetate/propionate synthase: ispF phosphatase: transaminase: [acp] (S)-2-acetolactate semialdehyde BM400_RS05220 A: BM400_RS18770 alpha-L-rhamnosidase: BM400_RS16050 pgl protein: reductase: fabG BM400_RS17225 (NADP(+)): reductoisomerase: synthase: AMP phosphoribosylanthranilate [+ 2 isozymes] biosynthesis II acetate- a peptide with BM400_RS13770 [+ 3 isozymes] glnD BM400_RS18960 3-hydroxyacyl- BM400_RS16080 family kinase: 2-C-methyl-D-erythritol- a proteinogenic a uridylylated BM400_RS18185 BM400_RS01935 BM400_RS20625 BM400_RS15195 BM400_RS18115 isomerase: BM400_RS00835 CMP BM400_RS04160 [+ 7 isozymes] [+ 2 isozymes] BM400_RS11060 cyclohydrolase: ketol-acid 4-hydroxy- an L-asparaginyl- acetyl phosphate BM400_RS07815 -CoA acetyl-CoA 1-oleoyl-2-palmitoyl- diphosphate AMP octanoyl-CoA D-gluconate an N-terminal a leader sequence a peptide 2-oxobutanoate cys (2E,11Z)- 1-deoxy-D- a [protein]- [acyl-carrier- 2-iminobutanoate bifunctional glutamate D-erythrose 2,4-cyclodiphosphate β-L-rhamnopyranose quercetin amino acid PII protein palmitate a retinol a (3R,7Z)-3-hydroxy- 2-oxoglutarate pyruvate RS01650 BM400_RS01610 reductoisomerase: tetrahydrodipicolinate gln 1-(o-carboxyphenylamino)-1'- Asn pyruvate F6P 3-keto-L-gulonate ligase: acs phosphatidylglycerol 6-phosphate L-proline xylulose 5- L-histidine Ins(3)P protein] N-acetyltransferase/ [tRNA ] 4-phosphate acetate kinase: hexadec-7-enoyl-[acp] octadecenoyl-CoA 1-(5-phospho-β-D-ribosyl)- alanine 6-phosphate phosphate BM400_RS17580 synthase: deoxyribulose 5'-phosphate acetate/propionate BM400_RS01455 RS02955 dehydratase amino-acid aminoacyl-tRNA transaminase: 5-[(5-phosphoribosylamino) (2R)-2,3- BM400_RS20440 carbamoyl-phosphate family kinase: FabZ: fabZ acetyltransferase indole-3-glycerol- hydrolase: transketolase: tkt acetyl phosphate acetyl-CoA methylideneamino]imidazole- dihydroxy-3- (2S,4S)-4- BM400_RS18115 synthase small subunit: N-acetyl-L-ornithine phosphate synthase: BM400_RS07815 N-acetyl-D-glucosaminyl-N- a 3-(acyloxy) a [protein]- hydroxy-2,3,4,5- ArgJ: BM400_RS12940 BM400_RS07915 1-(3-sn-phosphatidyl)- (5Z)- (S)-4-hydroxy- a (2E)-dec- 4-carboxamide methylbutanoate BM400_RS14250 BM400_RS00830 ala D-glyceraldehyde naringin a ferrocytochrome a ferrocytochrome an N-modified [EntB aryl- Kdo CTP a (3R,5Z)-3-hydroxy- τ RS12560 2-oxobutanoate L-xylulose acetate kinase: acetylmuramoyl-L-alanyl-D-glutamyl- palmitoyl-CoA stearoyl-CoA acyl group of L-cystathionine coenzyme A tetradecenoyl-CoA 2-oxopentanoate a hexanoyl-[acp] N -phospho- cys 2-enoyl-[acp] 1-(5-phosphoribosyl) dihydroxy-acid tetrahydrodipicolinate 3-phosphate sn-glycerol 3-phosphate b b aminoacyl-[tRNA] carrier protein] tetradec-5-enoyl-[acp] ATP carbamoyl-phosphate asn BM400_RS01455 alpha-L-rhamnosidase: 5 5 3-deoxy-manno- acyl-CoA L-histidine RS15900 (1S,2R)-1-C-(indol-3- 5-phosphate 6-carboxy-L-lysyl-D-alanine acyl-CoA acyl-CoA aminoacyl-tRNA bacterial toxinacyloxyacyl cystathionine holo-ACP 3-oxoacyl-[acyl- 2-keto-4- -5-((5- dehydratase: acetolactate 4-hydroxy- LD-carboxypeptidase: BM400_RS14040 octulosonate enoyl-ACP phosphohistidine cystathionine decanoyl-[acyl- synthase large yl)glycerol 3-phosphate phosphatidylglycerophosphatase desaturase: desaturase: hydrolase: hydrolase: beta-lyase: synthase: carrier-protein] dehydrogenase: pentenoate phosphoribosylamino) BM400_RS17905 tetrahydrodipicolinate glyoxylate cycle acetate BM400_RS21290 phosphatase: carrier-protein] synthase subunit: carB phosphate A: BM400_RS18770 N-acetyl-D-glucosaminyl-N- alpha-L-rhamnosidase: cytidylyltransferase: BM400_RS17225 hydratase: reductase: adenylyl cyclase: gamma-lyase: reductase: dapB BM400_RS12020 BM400_RS12020 BM400_RS07915 a 3-hydroxyacylBM400_RS17495 BM400_RS11000 acpS reductase: fabG reductase: methylideneamino) 3-methyl-2- small subunit: tryptophan synthase acetyltransferase D-ala acetylmuramoyl-L-alanyl-D- BM400_RS04160 an uncharged kdsB BM400_RS15255 BM400_RS20625 BM400_RS01515 BM400_RS18960 L-methionine biosynthesis III Secondary Metabolite Degradation a ferricytochrome a ferricytochrome an N-modified a holo-[EntB aryl- [+ 7 isozymes] [+ 2 isozymes] BM400_RS13045 RS18825 imidazole-4- BM400_RS17585 (S)-2,3,4,5- carbamoyl phosphate L-ornithine subunit alpha: an L-1-phosphatidyl- palmitoleoyl-CoA oleoyl-CoA a fatty acid group of L-homocysteine pyruvate 3',5'-ADP (2E,5Z)- 2-oxopent- a [protein]- BM400_RS02475 oxobutanoate succinate L-ribulose 5- D-gluconate PlsX: glutamyl-6-carboxy-L-lysine β-L-rhamnopyranose prunin b b amino acid tRNA carrier protein] CMP-Kdo a (5Z)-3-oxo- a (2E)-hex- pyruvate superpathway of L-cysteine sn-glycerol 5 5 bacterial toxin cyclic-AMP RS13730 carboxamide isomerase: tetrahydrodipicolinate BM400_RS02700 acetyl-CoA glyoxylate phosphate BM400_RS05220 tetradecenoyl-CoA 4-enoate L-histidine 2,3,4-saturated fatty acetolactate biosynthesis (mammalian) degradation tetradec-5-enoyl-[acp] 2-enoyl-[acp] BM400_RS01560 isocitrate lyase/ anhydromuropeptides recycling I 2-isopropylmalate branched-chain synthase, 2,3,4,5- tryptophan synthase L-homoserine malate synthase A: D-sorbitol degradation I acyl-[acp]:NAD+ phosphoenolpyruvate L-ribulose-5- synthase: amino acid tetrahydropyridine- subunit beta: trpB homoserine oxidoreductase: phosphoribulosylformimino- large subunit, BM400_RS13040 phosphate D-gluconate GlcNAc-1,6- BM400_RS17620 met acetyltransferase: mutase family protein: β RS01240 AICAR-phosphate transaminase: biosynthetic 2,6-dicarboxylate N- ser 4-epimerase gluconate kinase: anhMurNAc- D-sorbitol UDP-N-acetyl-α-D-muramoyl- an [eIF5A- 527 adenosyl- ADP-D-glycero- - BM400_RS15255 indole BM400_RS11945 a 5-L-glutamyl- a single L-threo-3- [EntF L-seryl- a guanine a D-hexose RS20700 BM400_RS08110 succinyltransferase: ornithine BM400_RS02455 γ D-alanyl-D-alanine isovalerate spermidine porphobilinogen 2-hydroxyisobutyramide oleoyl-CoA cobyrinate D-manno-heptose phosphoenol type: ilvB methionine AraD: araD BM400_RS18055 L-Ala- -D-Glu- sorbitol L-alanyl-γ-D-glutamyl-L-lysine an amino acid 4'-phosphopantetheine ATP stranded DNA precursor]-lysine coenzyme A in 16S rRNA a palmitoyl-[acp] dGDP (2S)-2- BM400_RS20445 hydrogen sulfide O-acetyl-L-homoserine D-gluconate [peptide] deoxyhypusine phenylserine carrier protein] acyl-CoA a,c-diamide ADP- pyruvate a decanoyl-[acp] (S)-2-aceto-2- carbamoyltransferase: D-xylulose DAP-D-Ala dehydrogenase: UDP-N-acetylmuramoyl- acetate--CoA low specificity L- hydroxymethylbilane holo-ACP amidase: 16S rRNA imidazole adenosyltransferase: 6-phosphate gamma- cobyric acid enoyl-ACP glucokinase: isopropylmalate N-succinyl-2-amino- argF tryptophan synthase BM400_RS18895 tripeptide--D-alanyl- pantetheine-phosphate ligase: acs deoxyribonuclease synthase: (guanine(527)-N(7) dehydrogenase: glyceromanno- pyruvate glycerol hydroxybutanoate BM400_RS01520 5-phosphate glutamyltransferase: ggt threonine aldolase: synthase: synthase: BM400_RS05830 glk val D-threo-isocitrate (S)-malate an α-(5-L- adenylyltransferase: IV: BM400_RS09555 BM400_RS08225 BM400_RS17225 synthase: reductase: heptose 6- 3-oxoacyl- 3-isopropylmalate 6-ketopimelate subunit beta: trpB sorbitol D- alanine ligase: an [eIF5A- BM400_RS13475 BM400_RS10535 acpS [+ 5 isozymes] )-methyltransferase kinase: pyk RS01830 phosphate ketol-acid a holo-[EntF BM400_RS16475 BM400_RS15255 epimerase: rfaD dehydratase BM400_RS09535 a peptide glutamyl)- BM400_RS07675 isovaleryl-CoA AMP diphosphate propane- 7 RsmG: rsmG [+ 2 isozymes] RS06395 [acyl-carrier- synthase reductoisomerase: SAM dehydrogenase: α precursor]- gly benzaldehyde 3',5'-ADP L-seryl-carrier 2-hydroxy-2- an N - ADP-L-glycero-β- D-hexose 6- β γ UDP-N-acetyl- -D-muramoyl-L-alanyl- amino acid 3'-dephospho-CoA a 5'-phosphooligonucleotide 1,3-diamine preuroporphyrinogen (2E,9Z)- a (2E)-hexadec- dGTP pyruvate protein] small subunit: leuD aconitate malate N-acetyl- -D- L-alanyl- -D- BM400_RS01190 deoxyhypusine methylpropanoate 527 adenosylcobyrate phosphate subunit BM400_RS17580 L-homocysteine γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine protein] methylguanine octadecenoyl-CoA D-manno-heptose trp glucosamine-1,6- glutamyl-meso-2,6- 2-enoyl-[acp] reductase: HisH: hisH 3-isopropylmalate hydratase: dehydrogenase: keto-D-fructose in 16S rRNA (R)-2,3-dihydroxy- N-succinyl-L,L-2,6- fabG dehydratase L-citrulline 5-methyltetrahydrofolate- acnA mdh anhydro-N-acetyl- diaminopimeloyl- imidazole glycerol 3-methylpentanoate diaminopimelate 5-methyltetrahydropteroyltriglutamate- β RS19900 β large subunit: leuC -homocysteine -D-muramate D-alanine RseP -ketododecanoyl- an N-acetyl-α- an N-formyl-L- 3-oxo- 966 two reduced phosphate dihydroxy-acid - homocysteine methyltransferase: beta-N- LD- UDP-N-acetylmuramoyl-L- 3-[(1- a guanine (3E)-5-chloro-2- orotidine 5'- [acp] synthase: argininosuccinate methyltransferase: pyruvate orotidine 5'- preuroporphyrinogen uroporphyrinogen-I cobyrinate synthase 2-isopropylmaleate dehydratase: SAH BM400_RS05915 cis-aconitate acetyl-CoA oxaloacetate carboxypeptidase: D-glucosaminide alanyl-γ-D-glutamyl-meso-2,6- methionylaminoacyl- (6Z,9Z,12Z,15Z,18Z,21Z) thr SAM carboxyvinyl) cysteine residues a myristoyl-[acp] phosphoenol synthase: BM400_RS10980 acetylhexosaminidase: phosphate in 16S rRNA oxopent-3-enoate dADP phosphate BM400_RS13030 subunit HisF: BM400_RS17905 Amine and Polyamine Degradation β-D-fructofuranose pyruvate, phosphate alpha-N- diaminopimeloyl-D-alanine tRNA -tetracosahexaenoyl-CoA oxy]benzoate 16S rRNA 2-keto-4- in a protein pyruvate superpathway of L-serine [+ 2 isozymes] aconitate BM400_RS11480 BM400_RS21290 LD- orotate peptide acetyl-CoA C- low specificity L- aminofutalosine uroporphyrinogen- uroporphyrinogen cobyrinate a,c- orotidine-5'- a 3- 3-isopropylmalate L-arginine BM400_RS07725 methionine synthase: metH γ acetylglucosaminidase: protein-disulfide enoyl-ACP BM400_RS01570 (S)-3-methyl-2- and glycine biosynthesis I L-alanyl- -D- dikinase: BM400_RS17885 carboxypeptidase: phosphoribosyltransferase: deformylase: threonine aldolase: synthase MqnE: III synthase: decarboxylase: (guanine(966)-N(2) pentenoate diamide synthase: pyruvate oxododecanoyl- L,L-diaminopimelate degradation I hydratase: 1,6-anhydro-N- fructokinase: acyltransferase: reductase: phosphate RS13865 RS10920 dehydratase adenosylhomocysteinase: N-acetylglucosamine glutamyl-meso- BM400_RS02800 )-methyltransferase hydratase: reductase: kinase: pyk oxopentanoate L-arginino-succinate acnA β α UDP-N-acetyl-α-D-muramoyl-BM400_RS21290 BM400_RS08390 def BM400_RS17215 BM400_RS13475 BM400_RS08685 BM400_RS13015 BM400_RS06775 BM400_RS16515 decarboxylase: [acp] (arginase pathway) BM400_RS01645 3-phospho- met creatinine urea degradation I acetyl- -muramate BM400_RS03700 + a non glycosylated N-acetyl- -D- BM400_RS21060 BM400_RS15255 D-erythro- small subunit: leuD degradation I allantoin degradation diaminopimelate diphosphate AMP phosphoenolpyruvate H a L-methionylaminoacyl- docosahexaenoyl- 6-amino-6- 2 RsmD: rsmD BM400_RS13045 3-oxoacyl-ACP branched-chain citrate synthase: L-alanyl-γ-D-glutamyl- D-ala orotate PRPP formate acetyl-CoA gly acetaldehyde met an N - cob(II)yrinate pyrF AICAR diaminopimelate D-glycerate degradation I anhydro-N- sugar acceptor glucosamine tRNA uroporphyrinogen-III coproporphyrinogen I 5-chloro-4-hydroxy- an intra- dATP pyruvate imidazole-glycerol- 3-isopropylmalate argininosuccinate phosphoglycerate BM400_RS20520 to ureidoglycolate II CoA deoxyfutalosine 966 a (2E)-tetradec- reductase: amino acid arg N-acetyl-D- F6P meso-2,6-diaminopimelate methylguanine protein disulfide a,c-diamide UMP phosphate epimerase: dapF lyase: argH ser (ammonia producing) acetylmuramic 2-oxopentanoate 2-enoyl-[acp] dehydratase dehydrogenase: S-adenosyl-L-methionine cycle II glucosamine urea in 16S rRNA BM400_RS02475 transaminase: L-homocysteine creatinine acid kinase: RS20790 imidazoleglycerol- large subunit: leuC argininosuccinate BM400_RS04440 citrate urea carboxylase: RS08190 [+ 7 isozymes] BM400_RS08110 6-phosphateN-acetylglucosamine- (S)-(+)-allantoin phosphate meso-diaminopimelate 3-phosphooxypyruvate creatininase: BM400_RS10495 a (3R)-3- (2R,3S)-3- lyase: argH allantoinase: BM400_RS09390 L-ornithine met 6-phosphate BM400_RS01790 N-acetyl-D- β α-Kdo-(2->4)- an N-acetyl-β- RNase III mRNA dehydratase HisB: [+ 2 isozymes] superpathway of -D- α 5-amino-4- a single a ribonucleoside (S)-4-amino-5- a [protein]- hydroxydodecanoyl- isopropylmalate ile methionine deacetylase: BM400_RS08130 muramate 6- adenosylcobinamide-GDP -ribazole PRPP α glu an oligopeptide 4-guanidinobutyramide NMN 2-deoxygluconate [DNA] 3-ethylmalate chorismate BM400_RS01585 arg phosphoserine urea-1-carboxylate glucuronosides degradation imidazolecarboxyamide a myristoyl-[acp] -Kdo-(2->6)- D-hexosaminide processing a tRNA L-allo-threonine a butanoyl-[acp] L-histidine [acp] 3-isopropylmalate diaminopimelate allantoinase creatine beta-N- stranded DNA triphosphate oxopentanoate ornithine- transaminase: adenosyltransferase: BM400_RS10745 phosphate adenosylcobinamide-GDP adenine (lauroyl)-lipid IV substrate DNA peptidyl- bifunctional 2-deoxy-D- decarboxylase: lysA lipid A biosynthesisA glutamyl-tRNA low specificity L- amidase: 3-isopropylmalate histidine kinase: RS01985 3-hydroxyacyl- imidazole acetol- dehydrogenase: AllB: allB acetylhexosaminidase: ribonuclease dipeptidase Dcp: DNA polymerase: enoyl-ACP chorismate RS06315 -oxo-acid L-homoserine BM400_RS11695 5-methyltetrahydropteroyltriglutamate- BM400_RS01520 N-acetylglucosamine- allophanate N-acetylmuramic a β-D-glucuronoside ribazoletransferase: cobS phosphoribosyltransferase: acyltransferase: primase: reductase: threonine aldolase: BM400_RS05830 metallophosphatase/ gluconate 3- dehydrogenase: BM400_RS08845 [acyl-carrier- phosphate leuB L-cystathionine allantoate ethanolamine BM400_RS11480 III: rnc BM400_RS12180 BM400_RS05595 reductase: mutase: pheA transaminase: biosynthesis - homocysteine methyltransferase: 6-phosphate hydrolase: atzF acid 6- beta-glucuronidase: BM400_RS21170 BM400_RS09960 RNase III dnaG BM400_RS10525 BM400_RS13475 5'-nucleotidase: dehydrogenase: leuB protein] lys 3-phospho- α-D-Kdo-(2->4) an N-acetyl-β- [+ 5 isozymes] [+ 7 isozymes] (2S)-2-isopropyl- rocD BM400_RS05915 deacetylase: nagA utilization phosphate BM400_RS10460 GMP adenosylcobalamin an mRNA fragment processing ssDNA/pppN(pN) an L-glutamyl- BM400_RS07335 BM400_RS10880 BM400_RS15255 a [protein]- aminotransferase: L-serine D-glucosamine allantoate AICAR acyl-carrier protein -α-D-Kdo- an alcohol acetaldehyde gly a dipeptide a peptide 1-(β-D a nucleoside 5'- dehydratase 3-oxosuccinate uracil degradation etherase: murQ D-hexosamine product mRNA hybrid [tRNA Glu ] 4-guanidinobutanoate 3-dehydro-2- a (2E)-but- 2-oxovalerate prephenate BM400_RS04305 [+ 2 isozymes] 6-phosphate amidohydrolase: ammonium beta-glucuronidase: n -1 N-phospho- biotin RS14850 biotin FabZ: fabZ L-glutamate-5- asp cystathionine (2->6)-lipid A ribofuranosyl) monophosphate RS05600 I (reductive) sarcosine ethanolamine deoxy-D-gluconate 2-enoyl-[acp] L-histidine semialdehyde lysine-sensitive BM400_RS19740 N-acetylmuramic BM400_RS04310 nicotinamide L-histidinol- gamma-lyase: ethanolamine a (2E)-dodec- uracil L-homocysteine SAM acid 6- D-glucopyranuronate phosphate aspartokinase 3: BM400_RS18960 2-enoyl-[acp] dihydropyrimidine L-glutamate (S)-ureidoglycine ammonia-lyase 4-methyl-2- BM400_RS20410 phosphate a 2'- (5E)-3-oxo- SecG gamma- α-D-glucosamine subunit EutC: a [glycine-cleavage 3-oxo-2-(cis-2'-pentenyl)- 3-oxo-(7Z)- dehydrogenase: L-aspartyl- ser etherase: murQ acetyl-CoA isobutanoate (+)-7-epi-jasmonoyl-CoA acetyl-CoA an all-trans-retinyl ester uroporphyrinogen-III oxaloacetate (Z)-hex-3-en-ol pyridoxal long chain citrate dodecanoyl-[acyl- oxopentanoate semialdehyde (2Z)-2-aminobut- 6-phosphate (S)-ureidoglycine BM400_RS02540 SAM complex H protein] a sulfurated [sulfur carrier] deoxyribonucleoside [DNA] dodec-5- an acyl phosphate a stearoyl-[acp] RS17950 BM400_RS15875 S-adenosyl-L-methionine cycle I 4-phosphate N-acetyl-D- cyclopentane-1-hexanoyl-CoA hexadecenoyl-CoA biotin ATP polyphosphate carrier-protein] 2-enoate cys aminohydrolase: 6 acetyl-CoA C- acetyl-CoA C- carboxylesterase/ acetyl-CoA C- 5'-triphosphate enoyl-CoA branched-chain dehydrogenase: gly ethanolamine glucosamine N -octanoyl-L-lysine acetate--CoA DNA polymerase: uroporphyrinogen-III acetyl-CoA C- phosphoenolpyruvate CHAT domain- 3-oxoacyl-[acyl- aconitate serine glucosamine- aldehydo-D-glucuronate lipoyl enoyl-ACP reductase: amino acid 5,6-dihydrouracil pruA aspartate- BM400_RS19735 acyltransferase: ligase: acs acyltransferase: lipase family protein: acyltransferase: acylphosphatase: biotin--[acetyl-CoA- polyphosphate histidinol 6-phosphate ammonia lyase 6-phosphate synthase: lipA BM400_RS05595 C-methyltransferase: acyltransferase: carboxykinase (GTP) containing protein: carrier-protein] hydratase: BM400_RS02475 hydroxymethyltransferase: glyA a [glycine-cleavage BM400_RS17215 BM400_RS17215 BM400_RS18185 BM400_RS17215 carboxylase] ligase: reductase: transaminase: SAM semialdehyde adenosylhomocysteinase: large subunit: glucuronate [+ 8 isozymes] cobA BM400_RS17215 : BM400_RS08080 BM400_RS21165 BM400_RS01950 reductase: fabG kinase 1: ppk1 acnA RS09780 dihydropyrimidinase: deaminase: (S)-ureidoglycolate N-acetylglucosamine- an unsulfurated 3-oxo-2-(cis-2'-pentenyl)- 3-oxo-2-(cis-2'-pentenyl)- (5Z)- BM400_RS15255 2,3,4-saturated fatty histidinol BM400_RS08110 Glu dehydrogenase: 5'-deoxyadenosine met complex H protein] isobutanoyl-CoA AMP diphosphate a fatty acid all-trans-retinol acetyl-CoA (3E)-dec-3- BM400_RS06090 BM400_RS01645 BM400_RS10740 BM400_RS02545 6-phosphate isomerase: [sulfur carrier] [DNA] acetyl-CoA phosphoenol biotinyl-5'- (3Z)-hex-3- RS20185 hydA gly N 6 -lipoyl-L-lysine cyclopentane-1-(3-oxooctanoyl)-CoA cyclopentane-1-(3-oxobutanoyl)-CoA tetradecenoyl-CoA precorrin-2 enoyl-CoA a carboxylate a (2E)-octadec- 4-pyridoxolactone long chain D-threo-isocitrate acyl-[acp]:NAD+ dehydrogenase: asd 2-iminobutanoate acetaldehyde BM400_RS18340 pyruvate adenylate hydantoinase: SAH deacetylase: en-1-yl acetate polyphosphate oxidoreductase: hisD leu methionine L-glutamine F6P 2-enoyl-[acp] BM400_RS02505 L-aspartate- superpathway of L- BM400_RS10745 BM400_RS15255 adenosyltransferase: biosynthesis I D-fructuronate histidinal semialdehyde asparagine biosynthesis N-acetylglucosamine- RS07240 3-ureidopropanoate BM400_RS01520 homoserine 6-phosphate all-trans- 34 RS09180 a dodecanoyl-[acp] Glu 3-oxo-2-(cis-2'-pentenyl)- 3-oxo-(9Z)- an N-acylated an adenosine an organic (indol-3-yl) phosphoenol histidinol L-alanine acetyl-CoA nicotinate PRPP methyl (indol-3-yl)acetate a formylmethanofuran myo-inositol α-bilirubin DNA with lesion met SAH dehydrogenase: ammonium asp deacetylase: nagA a 5-formiminotetrahydrofolate Glu octaprenyl 4-hydroxybenzoate aliphatic-L- a protein Arg2 cys biosynthesis III glutamine cyclopentane-1-butanoyl-CoA octadecenoyl-CoA in [tRNA ] hydroperoxide acetamide pyruvate dehydrogenase: BM400_RS19775 Detoxification acetyl-CoA C- diphosphate nicotinate carboxylesterase/ acetyl-CoA C- excinuclease synthetase: D-glucosamine 4-hydroxybenzoate amino acid formylmethanofuran metalloprotease tRNA adenosine(34) alkyl hydroperoxide amidase: hisD D-mannonate glutamate acylase: inositol oxygenase: cysteine bilirubin oxidase: pyruvate 3-oxoacyl- 6-phosphate acyltransferase: phosphoribosyltransferase: lipase family protein: acyltransferase: ABC subunit BM400_RS12625 formimidoyltransferase: ftcD octaprenyltransferase: BM400_RS04650 dehydrogenase: TldD: deaminase TadA: reductase: BM400_RS05830 RS11595 cys L-homoserine asparagine asparagine BM400_RS17215 BM400_RS08250 BM400_RS18185 BM400_RS17215 BM400_RS06150 dioxygenase: BM400_RS00095 A: uvrA kinase: pyk [acyl-carrier- 5-methyltetrahydropteroyltriglutamate- gln reactive oxygen species degradation phosphoglucosamine bifunctional BM400_RS09760 BM400_RS04900 BM400_RS02360 BM400_RS12580 BM400_RS12085 [+ 5 isozymes] RS06900 his β-alanine cysteine desulfurase: arsenate N-formimino- 3-oxo-2-(cis-2'-pentenyl)- (7Z)- an aliphatic BM400_RS11905 protein] - homocysteine methyltransferase: synthetase B: synthetase B: phenylmercury acetate degradation D-altronate/D- a tetrahydrofolate 3-octaprenyl-4- NaMN MeOH (indol-3-yl)acetate acetyl-CoA a carboxylate 34 [+ 4 isozymes] mutase: glmM L-glutamate L-amino acid D-glucopyranuronate a peptide a peptide an inosine laurate BM400_RS20530 BM400_RS10265 BM400_RS10265 detoxification cyclopentane-1-(3-oxohexanoyl)-CoA hydroxybenzoate hexadecenoyl-CoA a methanofuran an alcohol (indol-3-yl)acetate biliverdin-IX-α DNA without pyruvate reductase: BM400_RS05915 mannonate in [tRNA Arg2 ] 3-sulfinoalanine superoxide II (glutaredoxin) phosphoglucosamine lesion fabG S-ribosyl-L- cysteine desulfurase: mercuriphenyl dehydratase: long-chain fatty [+ 2 isozymes] L-homocysteine mutase: homocysteine BM400_RS02085 acetate arsenate BM400_RS10875 RS01615 β-ketomeristoyl- acid--CoA ligase: superoxide BM400_RS07690 RS17085 ala asn asn arsenate [acp] synthase: BM400_RS16050 dismutase: D-glucosamine D-mannonate salicyl-6-hydroxy-2- a 2,3,4-saturated 3-oxo-(6Z,9Z,12Z,15Z,18Z) 3-oxo-(7Z)- (2R,3S,4S)- (5Z)- (2S)- a [protein]- BM400_RS05950 reductase ArsC: dehydratase: α-D- an α-limit dextrin an L-cysteinyl- 2-deoxy-D-ribose BM400_RS13030 1-phosphate an acyl-[acyl-carrier protein] a malonyl-[acp] CTP 1,2-diacyl-sn- all-trans-retinyl palmitate icosapentaenoate coenzyme A N,N-dimethylaniline 5-aminolevulinate N-phospho- lauroyl-CoA BM400_RS07145 cyclohexene-on-oyl -tetracosapentaenoyl-CoA tetradecenoyl-CoA glucopyranose ATP leucopelargonidin Cys dodecenoyl-CoA ethylmalonyl-CoA hydrogen BM400_RS15150 [tRNA ] arsenite UDP-N- carboxylesterase/ glycerol 3-phosphate acetyl-CoA C- carboxylesterase/ long-chain fatty acetyl-CoA C- 4-alpha- dihydroflavonol dimethylaniline aminoacyl-tRNA porphobilinogen acyl-CoA methylmalonyl- L-histidine 3-oxoacyl-[acyl-carrier- phosphatidate 1-phosphate phosphohistidine ribokinase: RS16110 a 3-oxotetradecanoyl- peroxide Hg 2+ benzene acetate 2-dehydro-3- lipase family protein: acyltransferase: lipase family protein: acid--CoA ligase: acyltransferase: glucose-1-phosphate glucanotransferase: dehydrogenase: XrtJ acetylglucosamine protein] reductase: fabG cytidylyltransferase: 4-reductase: monooxygenase: hydrolase: synthase: CoA BM400_RS18185 BM400_RS17215 BM400_RS18185 BM400_RS16050 BM400_RS17215 BM400_RS17225 phosphatase: rbsK [acp] diphosphorylase/ deoxy-D-gluconate BM400_RS11220 adenylyltransferase: malQ BM400_RS13900 BM400_RS13925 BM400_RS07915 BM400_RS03500 epimerase: mce catalase/ mercuric reductase: acyl-carrier protein a 3-oxoacyl-[acp] 6-hydroxy-2-cyclohexen- a CDP-2,3,4-saturated- (4Z,7Z,10Z,13Z,16Z)- icosapentaenoyl- (5Z)- a α-limit dextrin BM400_RS20625 glucosamine-1- 2-dehydro-3- salicyl alcohol acetyl-CoA palmitate all-trans-retinol acetyl-CoA glgC Cys [+ 2 isozymes] 2-deoxy-D-ribose 3-oxoacyl-ACP one-carboxylate docosapentaenoyl-CoA CoA dodecenoyl-CoA N,N-dimethylaniline- a tRNA cys (2R)- a [protein]- Nucleoside and Nucleotide Biosynthesis peroxidase BM400_RS18195 diacylglycerol ADP-α-D-glucose with short branches (+)-dihydrokaempferol porphobilinogen (2E,5Z)- 5-phosphate reductase: phosphate N- deoxygluconokinase: N-oxide ethylmalonyl-CoA HPI: katG dodecenoyl-CoA L-histidine stearate biosynthesis arsenite acetyltransferase: BM400_RS17370 RS01235 RS12205 BM400_RS02475 H O hydroxyl radical Hg 0 II (bacteria and plants) superpathway of guanosine [+ 2 isozymes] 2 glmU [+ 7 isozymes] inosine-5'-phosphate biosynthesis I superpathway of 5-aminoimidazole superpathway of pyrimidine deoxyribonucleoside salvage CMP nucleotides de novo biosynthesis I superpathway of adenosine adenine salvage KDGP a (3R)-3- ribonucleotide biosynthesis phosphorylation N-acetyl-α-D- a 2-O-acetylated an (R)-2- 3-oxo-(9Z)- 3-oxo-(11Z)- N,N'- a (2R,3R)- a monocarboxylic a negatively galactitol 1- nucleotides de novo biosynthesis I a proteinogenic a carboxylic ester folate an aryl sulfate nicotinamide D-glucopyranose hydroxytetradecanoyl- a palmitoyl-[acp] 2'-deoxycytidine O glucosamine DL-allothreonine leukotriene-C4 rhamnogalacturonan I halocarboxylate hexadecenoyl-CoA octadecenoyl-CoA diacetylchitobiose a mercapturate dihydroflavonol acid amide supercoiled DNA phosphate 2 2-dehydro-3- amino acid 3-oxo-stearoyl- AIR CMP rhamnogalacturonan HAD family carboxylesterase/ acetyl-CoA C- acetyl-CoA C- glutamate galactitol-1- [acp] IMP PRPP 1-phosphate beta-N- dihydroflavonol amidase: type I DNA sulfatase: xylose RS08240 RS00450 5-(carboxyamino) (d)CMP kinase: adenine deoxyphosphogluconate serine gamma- acetylesterase: acylase: nicotinamidase: 3-hydroxyacyl- [acp] synthase: asp IMP cytidine deaminase: hydrolase: lipase family protein: acyltransferase: acyltransferase: acetylhexosaminidase: carboxypeptidase: phosphate 5- isomerase: amidophosphoribosyltransferase: UDP-N- aldolase: BM400_RS17365 hydroxymethyltransferase: glyA glutamyltransferase: ggt BM400_RS04650 4-reductase: BM400_RS05830 topoisomerase: BM400_RS11870 BM400_RS13030 imidazole ribonucleotide BM400_RS20000 BM400_RS10310 BM400_RS04850 BM400_RS18185 BM400_RS17215 BM400_RS17215 BM400_RS08955 dehydrogenase: BM400_RS11180 [acyl-carrier- BM400_RS00780 BM400_RS08270 acetylglucosamine an α-(γ-L-glutamyl) BM400_RS11480 BM400_RS13900 [+ 5 isozymes] BM400_RS18650 [+ 3 isozymes] xylA a 3-oxooctadecanoyl- IMP synthase: purK CDP D-glyceraldehyde leukotriene-D4 a rhamnogalacturonan an (S)-2- (7Z)- an L-cysteine- protein] 5-phospho-β- pyruvate gly acetaldehyde -L-amino acid acetate a halide anion a carboxylate an alcohol acetyl-CoA palmitoleoyl-CoA acetyl-CoA N-acetyl-D- acetate BM400_RS02480 [acp] dehydrogenase: dCMP diphosphorylase/ type I S-conjugate glutamate pteroate a (2R,3S,4S)- keto-D-tagatose keto-D-fructose adenylosuccinate N5-CAIR D-ribosylamine nucleoside- adenine adenine 3-phosphate hydroxycarboxylate tetradecenoyl-CoA glucosamine a monocarboxylate a relaxed DNA a phenol nicotinate dehydratase 2'-deoxyuridine selenate reduction Inorganic Nutrient Metabolism glucosamine-1- leucoanthocyanidin 3-oxoacyl-ACP BM400_RS19035 synthase: phosphoribosyltransferase: sulfate reduction 6-phosphate RS10170 RS13965 FabZ: fabZ phosphoribosylamine- (d)CMP kinase: diphosphate deaminase: 5-(carboxyamino)imidazole phosphate N- reductase: BM400_RS05315 BM400_RS20000 kinase: BM400_RS07780 BM400_RS21170 III (assimilatory) -glycine ligase: thymidine kinase: acetyltransferase: a (2E)-tetradec- BM400_RS02475 XMP ribonucleotide mutase: purE selenate BM400_RS00745 BM400_RS21380 dCDP BM400_RS21345 adenine a nascent peptidoglycan with (L- a 3-O-acetylated α-D- an α(1,5)- 4-(4-deoxy-α-D- 2-enoyl-[acp] adenylo-succinate sulfate sulfate glmU a single- an (S)-2- 4-hydroxybenzoyl- 3-oxo-4-pregnene- a double an organic dUDP [+ 7 isozymes] deaminase: alanyl-γ-D-glutamyl-meso-2,6- rhamnogalacturonan I glucopyranose CTP acetyl-CoA thiosulfate dithioerythritol VibB coenzyme A L-arabinan galact-4-enuronosyl) a peptide L-homoserine propionamide CAIR thymidine CTP adenylyltransferase UDP-N-acetyl- stranded RNA halocarboxylate CoA 20-carboxyl-CoA stranded DNA molecule nucleoside- myristoyl-[acyl- a (3R)-3- xanthosine-5'- GAR dUMP nucleoside- BM400_RS17730 AMP sulfate rhamnogalacturonan HAD family acetyl-CoA C- thiosulfate RS12190 adenylosuccinate α-D-glucosamine D-galactarate diaminopimeloyl-D-alanine) tetrapeptide polyribonucleotide 1-phosphate alpha-N- -D-galacturonate acetyl-CoA C- DNA gyrase amidase: RS20385 hydroxyoctadecanoyl- phosphate:L- diphosphate xanthine and subunit CysD: adenylyltransferase LD-carboxypeptidase: acetylesterase: glucose-1-phosphate holo-ACP oligogalacturonate folate hydrolase: cystathionine diphosphate carrier-protein] lyase: degradation II nucleotidyltransferase: pnp hydrolase: acyltransferase: reductase: arabinofuranosidase: cytochrome P450: phosphoribosylaminoimidazolesuccinocarboxamide phosphoribosylglycinamide thymidine kinase: BM400_RS09205 UDP-N-acetylglucosamine BM400_RS21290 synthase: acpS BM400_RS01460 acyltransferase: subunit A: BM400_RS05830 kinase: reductase: [acp] glutamine kinase: xanthosine salvage subunit CysD: a nascent peptidoglycan with a nucleoside a single- BM400_RS10310 BM400_RS04850 cytidylyltransferase: BM400_RS17215 BM400_RS05200 lyase: gamma-lyase: BM400_RS15045 BM400_RS20865 synthase: BM400_RS12320 formyltransferase: BM400_RS21380 BM400_RS05530 BM400_RS17215 BM400_RS00655 [+ 5 isozymes] 3-hydroxyacyl- amido-ligase BM400_RS21345 BM400_RS09205 1-carboxyvinyltransferase: a rhamnogalacturonan an (S)-2- rfbF 4-hydroxybenzoyl- 4,5-cis-dihydroxy- a holo-[VibB aryl- BM400_RS17340 BM400_RS18960 BM400_RS21345 BM400_RS02475 hypoxanthine sulfate D-galactarate D-ala (L-alanyl-γ-D-glutamyl-meso- diphosphate stranded RNA acetate a halide anion sulfite 3',5'-ADP α-L- Glu a peptide [acyl-carrier- (AMP-forming): BM400_RS04690 murA type I hydroxycarboxylate CDP-α-D-glucose acetyl-CoA 1,2-dithiacyclohexane carrier protein] 5-dehydro-4-deoxy- 3,22-dioxochol- a negatively dUTP 2,3,4-saturated fatty SAICAR dCTP adenylyltransferase sulfate D-galactarate 2,6-diaminopimelate) tripeptide arabinofuranose 2-oxobutanoate propanoate an alcohol RS02320 protein] BM400_RS09670 AMP xanthosine urea cycle UDP-N-acetyl-α- D-glucuronate 4-en-24-oyl-CoA supercoiled DNA RS15520 acyl-[acp]:NAD+ FGAR subunit CysN: adenylyltransferase dehydratase: dehydratase hypoxanthine purine-nucleoside BM400_RS09210 subunit CysN: D-glucosamine- oxidoreductase: adenylosuccinate dTMP adenosine 5'- BM400_RS01165 FabZ: fabZ GMP phosphoribosylformylglycinamidine phosphoribosyltransferase: hpt phosphorylase: BM400_RS09210 ammonium enolpyruvate BM400_RS15255 adenylate kinase: lyase: BM400_RS20865 phosphoselenate galactarate N,N',N''- N-acetyl-D- adenine and adenosine salvage III BM400_RS08315 UDP-N- 5,10-methylene- 3-methyl-2- a glucan maltotriose 6-cis, 3-oxo- 5-cis, 7-trans-3-oxo- 3-[(5'-methylthio) (2R,3S)-3- sulfate RS21040 sulfate a (2E)-octadec- BM400_RS19155 synthase: BM400_RS06765 dTMP kinase: tmk APS arg MEP CTP decanoyl-CoA acetyl-CoA sec an oligopeptide Ins(2)P meso-tartrate acetamide xanthine phosphoadenylyl- dehydratase: tetrahydromethanopterin oxobutanoate glutathione hypoglycin A triacetylchitotriose tridecenoyl-CoA tetradecadienoyl-CoA a tRNA ser mannosamine pentyl]malate isopropylmalate AICAR [+ 2 isozymes] carbamoyl- acetylenolpyruvoylglucosamine 4-alpha- a myristoyl-[acp] 2-enoyl-[acp] guanylate kinase: IMP garD 3-methyl-2-oxobutanoate beta-N- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- S9 family N-acetylneuraminate RS02490 sulfate reductase: phosphoadenylyl- phosphate reductase: BM400_RS17140 gamma- 2-C-methyl-D- serine--tRNA ligase: 3-isopropylmalate 3-isopropylmalate inositol tartrate amidase: dTDP 5-dehydro-4- hydroxymethyltransferase: acetylhexosaminidase: glucanotransferase: acyltransferase: acyltransferase: acyltransferase: peptidase: sulfate RS04490 sulfate steroyl-[acp] BM400_RS09920 ADP bifunctional FGAM BM400_RS09215 sulfate reductase: erythritol 4-phosphate synthase: dehydrogenase: dehydrogenase: dehydrogenase: BM400_RS04385 adenine synthase UDP-N-acetyl- deoxy-D-glucarate glutamyltransferase: ggt malQ BM400_RS11255 monophosphatase: 3-oxoacyl- reductase: nucleoside- panB BM400_RS11480 BM400_RS17215 BM400_RS17215 BM400_RS17215 BM400_RS13540 BM400_RS08625 phosphoribosylaminoimidazolecarboxamide purine-nucleoside superpathway of pyrimidine BM400_RS09215 small subunit: α-D-muramate N-acetyl-D- N,N'- cytidylyltransferase: ispD an L-seryl- leuB leuB BM400_RS09810 BM400_RS10235 [+ 5 isozymes] [acyl-carrier- selenite 5-dehydro-4- L-cysteinyl-glycine hypoglycin B 4-(cytidine 5'-diphospho) D-glucopyranose a glucan 4-cis- (3Z,5E)-dodeca- 3-oxododecanoyl- N-acetyl-β- BM400_RS02475 formyltransferase/IMP cyclohydrolase phosphoribosylformylglycinamidine diphosphate argininosuccinate THMPT 2-dehydropantoate acetyl-CoA acetyl-CoA [tRNA sec ] a peptide a peptide 8-(methylthio)- 4-methyl-2- 2-hydroxy-3- sulfate RS19950 sulfate GDP phosphorylase: nucleobases salvage BM400_RS14250 glucosamine diacetylchitobiose -2-C-methyl-D-erythritol undecenoyl-CoA 3,5-dienoyl-CoA protein] kinase: sulfite UDP-N- deoxyglucarate CoA neuraminate myo-inositol acetate 2,3,4-saturated fatty PurH: BM400_RS11275 cyclo-ligase: BM400_RS04695 BM400_RS08315 XMP lyase: argH 2-oxooctanoate oxopentanoate oxosuccinate RS06365 reductase: F0F1 ATP ribonucleoside- uracil carbamoyl- acetylmuramate:L- dehydratase: acyl-[acp]:NAD+ BM400_RS21345 adenosine argininosuccinate sulfite RS11730 sulfite fabG synthase diphosphate bifunctional pyr operon phosphate kdgD FAICAR AIR lyase: argH alanyl-gamma-D- oxidoreductase: subunit reductase, dTTP L-arginino- β-ketopalmityl- fatty acid elongation -- saturated nucleoside- ribonucleoside- transcriptional regulator/uracil L-ornithine synthase glutamyl- meso- 2,5- a long-linear D-xylulose BM400_RS15255 adenosine deaminase: add succinate a proteinogenic α-D-glucopyranose 6-trans-3-oxo- 3-oxo- β-D-allopyranose 3-[(7'-methylthio) (2R,3S,4S)- (2R,3S,4S)- diphosphate diphosphate A: atpB adenosylcobalamin- bifunctional phosphoribosyltransferase selenodiglutathione large diaminopimelate dioxopentanoate glutathione glutathione glycyl-glycine α-D-glucan a ribonucleic acid (-)-methyl jasmonate hexanoyl-CoA acetyl-CoA H O diphosphate Ins(1)P acrylamide sulfite RS06215 sulfite [acp] synthase: adenine and adenosine deaminase: 5-phosphate tridecenoyl-CoA myristoyl-CoA 2 heptyl]malate leucodelphinidin leucocyanidin [+ 5 isozymes] dependent: phosphoribosylaminoimidazolecarboxamide H O amino acid 4-alpha- BM400_RS13030 kinase: reductase, PyrR: BM400_RS02865 2 subunit: carB ligase: mpl α gamma- phosphoketolase: ribonuclease PH: acetyl-CoA C- carboxylesterase/ acetyl-CoA C- acetyl-CoA C- inorganic RS13240 a stearoyl-[acp] adenosine salvage I guanine and guanosine salvage BM400_RS00990 argininosuccinate -ketoglutarate gamma- 3-isopropylmalate dihydroflavonol inositol dihydroflavonol amidase: an acetoacetyl-[acp] BM400_RS21345 BM400_RS19655 formyltransferase/IMP cyclohydrolase UMP glucanotransferase: acyltransferase: lipase family protein: acyltransferase: acyltransferase: D-ribose pyranase: adenosylcobalamin- pyrimidine synthase: carbamoyl semialdehyde glutamyltransferase: ggt BM400_RS01450 BM400_RS09640 diphosphatase: dehydrogenase: 4-reductase: 4-reductase: BM400_RS05830 sulfite RS05815 sulfite a 3-oxohexadecanoyl- PurH: BM400_RS11275 UDP-N-acetyl- glutamyltransferase: ggt malQ BM400_RS18925 monophosphatase: dependent: [+ 2 isozymes] an α-(γ-L-glutamyl) γ-L-glutamyl- D-glyceraldehyde a nucleoside BM400_RS17215 BM400_RS18185 BM400_RS17215 BM400_RS17215 BM400_RS06760 inosine UMP kinase: ribonucleosides salvage I BM400_RS07725 phosphate α-D-muramoyl- dehydrogenase: L-cysteinyl-glycine acetyl phosphate a ribonucleic acid leuB BM400_RS13900 BM400_RS09810 BM400_RS13900 [+ 5 isozymes] [acp] ATP ornithine L-cysteinyl-glycine glycylglycine a short glucan a short glucan 3-phosphate diphosphate 4-trans- 3-oxooctanoyl- BM400_RS19655 adenosine BM400_RS19680 BM400_RS05000 -L-amino acid acetyl-CoA MeOH (-)-jasmonate acetyl-CoA lauroyl-CoA phosphate H + 10-(methylthio)- (+)- an oxidized guanosine cytidine glutathioselenol L-alanyl-γ-D- undecenoyl-CoA CoA β-D-allofuranose 3-oxoacyl-ACP GTP IMP purine-nucleoside carbamoyltransferase: myo-inositol (+)-taxifolin acrylate c-type O [+ 2 isozymes] purine-nucleoside purine-nucleoside (d)CMP kinase: glutamyl-meso-2,6- 2-oxodecanoate dihydromyricetin MreD 2 reductase: dADP phosphorylase: argF 2-oxoglutarate cytochrome RS15120 stearate phosphorylase: phosphorylase: BM400_RS20000 diaminopimelate a reduced BM400_RS02475 BM400_RS08315 cytidine deaminase: an oxidized L-citrulline c-type H O a 3-oxoacyl-[acp] BM400_RS08315 BM400_RS08315 UDP BM400_RS08270 2 [+ 7 isozymes] long-chain fatty nucleoside- adenine a plant soluble c-type O dGDP guanine maltopentaose D-glucopyranose D-glucopyranose RNase R degradation 1-18:1-2- an (R)-2- O-ureido-L- 3-[(6'-methylthio) cytochrome 2 HMG-CoA chitin butanoyl-CoA acetyl-CoA methylsalicylate maltose D-glycerate hydroxypyruvate methylglyoxal (S)-malate a (3R)-3- acid--CoA ligase: diphosphate nucleoside-diphosphate CMP hydrogen selenide heteroglycan substrate RNA asp cytochrome RS03215 hypoxanthine uridine lysophosphatidylethanolamine halocarboxylate homoserine hexyl]malate a reduced hydroxyhexadecanoyl- adenine 4-alpha- 4-alpha- ribonuclease R: beta-N- HAD family acetyl-CoA C- carboxylesterase/ RS21075 an oxidized BM400_RS16050 3-oxoacyl- kinase: kinase: BM400_RS21345 hydroxymethylglutaryl-CoA lysophospholipase: argininosuccinate 3-isopropylmalate glycerate hydroxypyruvate glyoxalase: fumarate c-type H O nucleoside- glucanotransferase: malQ glucanotransferase: acetylhexosaminidase: alpha-glucosidase: 2 [acp] BM400_RS21345 phosphoribosyltransferase: hypoxanthine uridine kinase: lyase: BM400_RS12115 BM400_RS00235 BM400_RS11975 hydrolase: acyltransferase: lipase family protein: c-type O [acyl-carrier- diphosphate UTP synthase: dehydrogenase: dehydrogenase: isomerase: BM400_RS11170 hydratase: cytochrome 2 3-hydroxyacyl- stearoyl-CoA BM400_RS21170 malQ a nucleoside 5'- sn-glycero-3- BM400_RS11480 BM400_RS04850 BM400_RS17215 BM400_RS18185 BM400_RS15780 protein] phosphoribosyltransferase: hpt hypoxanthine BM400_RS08320 maltose maltotetraose acetyl-CoA acetoacetate oleate BM400_RS07725 leuB BM400_RS01105 BM400_RS01760 [+ 5 isozymes] BM400_RS20815 cytochrome RS15135 kinase: a plant soluble a diribonucleotide N-acetyl-D- an (R)-2- 3-oxohexanoyl- a reduced [acyl-carrier- phosphoribosyltransferase: hpt maltose monophosphate phosphoethanolamine chitin a halide anion MeOH salicylate an oxidized reductase: BM400_RS21345 dATP CTP synthase: pyrG UMP heteroglycan glucosamine canavaninosuccinate D-glucopyranose 9-(methylthio)- tartronate c-type H O protein] AMP hydroxyacid CoA hydroxypyruvate (R)-lactate fumarate c-type O 2 β-ketoacyl- fabG GMP 2-oxononanoate semialdehyde RS07330 cytochrome 2 dehydratase CTP cytochrome ACP synthase: [+ 7 isozymes] dGTP IMP a reduced CtaD FabZ: fabZ an oxidized c-type H O BM400_RS13030 a (3R)-3- α 2 a 2,3,4-saturated a 1-acyl-sn-glycero- 4-trans-3-oxo- 3-oxo- 3-oxo-(5Z)- 6,7-dimethyl-8-(1- 3-[(3'-methylthio) (R)-methylmalonyl- CDP- -D-glucose c-type O a (2E)-hexadec- hydroxyacyl-[acyl- a homogalacturonan a maltodextrin D-glucopyranose a peptidoglycan a penicillin a glycogen D-glucopyranose L-tartrate cytochrome 2 fatty acyl-[acp] 3-phosphocholine undecenoyl-CoA palmitoyl-CoA dodecenoyl-CoA a protein D-ribityl)lumazine propyl]malate CoA cytochrome 2-enoyl-[acp] 3-hydroxyacyl- polygalacturonase: CDP- a reduced RS03210 carrier protein] 4-alpha- lysozyme: penicillin amidase: lysophospholipase: glucan 1,4-alpha- acetyl-CoA C- acetyl-CoA C- acetyl-CoA C- riboflavin synthase 3-oxoacyl-ACP RS01725 an oxidized protease Do: 3-isopropylmalate methylmalonyl- tartrate glucose 4,6- c-type H O palmitoyl-[acyl- [acyl-carrier- BM400_RS00035 glucanotransferase: malQ BM400_RS00040 glucosidase: acyltransferase: acyltransferase: acyltransferase: subunit alpha: 2 BM400_RS19635 BM400_RS11975 dehydrogenase: reductase: CoA dehydrogenase: c-type O protein] a N-acetylmuramoyl- BM400_RS16135 dehydratase: cytochrome 2 carrier-protein] a homogalacturonan a homogalacturonan maltose a maltodextrin N-acetyl-D- sn-glycero-3- BM400_RS05955 BM400_RS17215 BM400_RS17215 BM400_RS17215 BM400_RS18855 BM400_RS12570 pentapeptide- a carboxylate 6-aminopenicillanate a carboxylate leuB epimerase: mce BM400_RS10235 rfbG cytochrome CoxB reductase: dehydratase glucosamine phosphocholine 2-trans- (3Z)-dec-3- a peptide a peptide a reduced D-glucopyranose a glycogen acetyl-CoA myristoyl-CoA acetyl-CoA acetyl-CoA riboflavin ARP D-glucono- (S)-methylmalonyl- 2-hydroxy-3- an oxidized FabZ: fabZ diphosphoundecaprenol nonenoyl-CoA enoyl-CoA 6-(methylthio)- CDP-4-dehydro- chloride RS16685 chloride c-type H O BM400_RS02475 1,5-lactone c-type 2 O 2-oxohexanoate CoA oxosuccinate 6-deoxy-D-glucose cytochrome 2 2,3,4-saturated fatty cytochrome RS20980 a reduced acyl-[acp]:NAD+ chloride RS06500 chloride an oxidized methyl-esterified a debranched c-type H O oxidoreductase: + 3-[(4'-methylthio) c-type O 2 maltohexaose maltose maltotetraose D-glucopyranose penicillin G maltohexaose maltopentaose a tripeptide octanoyl-CoA acetyl-CoA H malonyl-CoA O chloride a phenyl acetate ribulose pyrazinamide D-ribulose 2 a trans-2- homogalacturonan 2 α-limit dextrin cytochrome BM400_RS15255 enoyl-ACP butyl]malate cytochrome a 2,3,4-saturated 4-alpha- 4-alpha- alpha-glucosidase: alpha-glucosidase: pectin esterase: acetyl-CoA C- type III polyketide H + RS15560 H + a reduced CoxB enoyl-[acyl- penicillin amidase: peptidase T: chlorite dismutase: arylesterase: 3-isopropylmalate glucan 1,4-alpha- amidase: fatty acyl-[acp] reductase: glucanotransferase: malQ glucanotransferase: malQ BM400_RS15780 BM400_RS15780 BM400_RS18710 ribulokinase: ribulokinase: c-type H O carrier protein] BM400_RS19635 BM400_RS04065 acyltransferase: synthase: BM400_RS15205 BM400_RS08420 glucosidase: 2 a palmitoyl-[acp] BM400_RS15255 dehydrogenase: BM400_RS05830 RS09280 BM400_RS17215 BM400_RS00465 BM400_RS08435 BM400_RS08435 cytochrome D-glucopyranose maltoheptaose maltose maltotriose phenylacetate 6-aminopenicillanate D-glucopyranose maltopentaose D-glucopyranose maltotetraose MeOH a homogalacturonan a proteinogenic chlorite acetate a phenol leuB BM400_RS05955 [+ 5 isozymes] + + a dipeptide 3-oxodecanoyl- H RS07190 H amino acid octoketide 7-(methylthio)-2- L(or D)-ribulose pyrazine-2- D-ribulose CoA D-glucopyranose 2,3,4-saturated fatty oxoheptanoate 5-phosphate carboxylate 5-phosphate acyl-[acp]:NAD+ H + RS07195 H + RS17750 palmitate oxidoreductase: BM400_RS15255 a β-D-glucosyl-N a (1->4)- a [protein] N-terminal- 3-oxo-(5Z)- UTP α-L- aldehydo-D- uridine maltohexaose D-glucopyranose a sialyloligosaccharide maltoheptaose maltotriose a pectin cellulose H + RS07185 H + -acylsphingosine α-D-glucan asp fumarate hydroquinone rhamnopyranose galacturonate long-chain fatty formyl-L-methionine tetradecenoyl-CoA nucleoside triphosphate 4-alpha- exo-alpha-sialidase: glucosylceramidase: alpha-glucosidase: alpha-glucosidase: alpha-glucosidase: acetyl-CoA C- pectin esterase: acid--CoA ligase: peptide L-rhamnose glucuronate uridine kinase: BM400_RS19050 BM400_RS15780 BM400_RS15780 BM400_RS15780 L-aspartate pyrophosphohydrolase: cellulase: glucanotransferase: malQ BM400_RS18150 deformylase: def acyltransferase: BM400_RS18710 tyrosinase: mutarotase: isomerase: BM400_RS08320 BM400_RS16050 a (1->4)- oxidase: nadB BM400_RS21120 RS10180 a sphingosine an N-terminal L- BM400_RS17215 BM400_RS09320 BM400_RS13725 maltose maltopentaose N-acetylneuraminate an oligosaccharide D-glucopyranose D-glucopyranose maltohexaose D-glucopyranose D-glucopyranose maltose formate MeOH a pectate BM400_RS21325 BM400_RS18340 RS02645 ceramide α-D-glucan (3Z)-dodec- succinate 2-iminosuccinate UMP UMP palmitoyl-CoA methionyl-[protein] acetyl-CoA β-L- D-tagaturonate a cellodextrin 3-enoyl-CoA 1,4-benzoquinone rhamnopyranose

RS06990 a dicarboxylate phosphate a purine a purine molybdate an amino an amino an amino nucleoside nucleoside an inorganic an inorganic an phosphate a 2,3,4-saturated fatty acyl CoA α-L- a sulfonate a nucleotide D-glucose D-galactose D-galactose ammonium (S)-lactate a nucleoside acid acid acid anion anion oligopeptide phosphate cis-vaccenoyl-CoA a lipopolysaccharide a phospholipid rhamnopyranose predicted predicted ABC ABC RS14980 RS08850 RS16855 RS08245 RS11740 RS10735 RS10645 RS04910 RS20935 RS14910 RS10965 RS13150 RS04730 RS15630 RS01975 RS21315 RS19290 RS14820 RS14535 RS07385 RS01885 RS01820 RS20230 RS16795 RS15970 RS17820 RS13215 RS10440 RS16700 RS16100 RS14810 RS00710 RS13130 RS03635 RS08990 RS09620 GrpE LptB RS07985 RS20330 RS19375 RS17175 RS14985 RS18360 RS07305 RS08645 RS12090 RS08285 RS09260 RS11590 RS10295 RS01540 RS03960 RS11295 RS12430 RS10680 RS00915 RS05785 RS07720 RS09475 RS01920 RS13135 RS01435 RS06650 RS10665 RS16800 RS20195 RS00975 RS00360 RS07075 RS13535 RS13245 RS06805 RS02215 PstB RS06860 RS16050 RS11065 RS08455 RS02795 RS16595 RS10560 RS06100 RS20540 RS11350 RS03980 RS20585 RS15140 RS01305 RS11970 RS00055 RS21130 RS04085 RS20965 RS09450 RS10690 RS17230 MotA RS05345 RS12450 RS08170 RS16900 RS01505 RS02305 transporter transporter of molybdate of phosphate a 2,3,4-saturated fatty acid ammonium a phospholipid cis-vaccenate

α-L- D-glucose D-galactose D-galactose an inorganic an inorganic an amino an amino an a sulfonate a nucleotide a purine a purine molybdate (S)-lactate a nucleoside phosphate phosphate rhamnopyranose a lipopolysaccharide anion anion a dicarboxylatean amino oligopeptide nucleoside nucleoside acid acid phosphate acid This diagram was automatically generated by SRI International Pathway Tools version 25.0, authors S. Paley and P.D. Karp.