DOCSLIB.ORG

The Dietary Supplement Health and Education Act of Consulting Services, White Rock, B.C., Wade Davis, Ph.D

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
The Dietary Supplement Health and Education Act of Consulting Services, White Rock, B.C., Wade Davis, Ph.D New Products from ABC's Herbal Education Catalog The ABC Clinical Guide to Herbs Ed. by Mark Blumenthal et al. , Ameri can Botanical Council , 2003. How does the healthcare professional effectively respond to pati ent inquiries on the use of herbal supplements? What clinical research has been conducted? How is safety evaluated? T his science-based educati onal course answers these and other ques­ tions for healthcare professionals, pharmaceutical companies, health management compani es, policy makers, the dietary supplement industry and consumers. Hardcover, 512 pp. $49.95. #905 Quick Access Guide to Conditions, Herbs & Supplements by Integrative Medicine Communica ti ons, 2000. T his book has three broad categories for quick answers to consumer questio ns. T he largest section deals with co nditions and covers various treatment options incl uding herbs, supplements, drugs, and other complementary and alternative therapies. O nly alternative treatments that are considered safe and effective when used with conventional medicine are included. Additional sections on herbs and supplements cover bas ic informati on, precautions, and dosage informati on. T he Q uick Reference Guide fou nd at the end of the book shows at a glance all the herbs and supplements that are useful in treating that co ndition. Softcove r. 430 pp. $29.95. #B52 1. Special offe r $24.00! ~ Quick Access Patient Information on Conditions, Herbs I ..!~ I & Supplements ~. I by Integrative Medicine Communications. Consists of three types of monographs. Condition monographs ~ provide patients with information on standard medical care wi th additional information on nutritional ._. support and the use of alternative and complementary therapies. Herb monographs provide important info r- r marion on their use in maintaining health or treating conditions. Supplement monographs provide informa­ ti on on the use of dietary supplements. Thirteen Q uick Reference G uide lists allow easy and targe ted access to information by symptom, use, precautions, etc. Spiral bound. 266 pp. $49.95. #B522. Special offer $40.00! Quick Access Professional Guide to Conditions, Herbs & Supplements by Integrative Medicine Communications. Contains Condition, Herb, and Supplement Monographs with extensive info rmati on geared toward medical practitioners. T hirtee n Q ui ck References al low easy and targeted access to the information. 472 pp. H ardcover. $49.95. #B523. Special offer $40.00! Quick Access Professional Reference to Conditions, Herbs & Supplements CD-ROM by Integrative Medicine Communications. Monographs address numerous medical condi- tions, provide information on a range of treatment options, outline uses, dosages and interacti ons fo r over 11 5 herbs and supplements and present nutrition depletions associated with the most popular drugs. PC compatible. $49.95. #COOl. Special offer $40.00! Herba/Gram BackPacks Don't leave any gaps in your library. HerbalGram back iss ues provide a comprehensive store of info rma­ tion on herbs, book reviews, research, conference reports, and regul atory developments. BackPacks are a set of Herba fGrams from 1989, except the most current iss ue, and include a Cumul ative Index. Order a complete set of BackPacks (Volumes II, III and IV) for $95 and receive 2 slipcases to protect and store those back issues at no extra charge ($19 value). See inside back cover for more! To order, call toll free 800/373-7105, fax 512/926-2345, email: [email protected] or order online at www.herbalgram.org to see the complete Herbal Education Catalog and to see fNIERIGAN special offers, visit us online at: BoTANICAL www.herbalgram.org/bookcatalog COUNCIL Individuals, organizations, and companies who share our vision support our goals through membership. The American Botanical Council Invites You to e r-------------------------, Yes, I want to join ABC! Pl ease detach application and mail to: o1n American Botanical Council , P.O. Box 144345, Austin, TX 78714-4345 or join online at www. herbalgra m. org To join, please fill out this form or call us at 800/373-7105 x 119 or 0 Individual - $50 fill out an application online at www.herbalgram.org 0 Academic- $ 100 0 Professional - $ 150 0 Organization - $250 Membership Level 5 Please add $20 fo r addresses outside the U.S. (Add $20 postage for international delivery for above levels.) 0 Corporate and Sponsor levels . Individual -$50 Academic - $1 00 (Contact Wayne Silverman, PhD. 512/926-4900. ext. 120.) • Subscription to our highly All Individual membership Payment instructions acclaimed journal Herbal­ benefits, plus 0 C harge credit card (Visa or MC only) Gram • Online access to HerbCiip # _____________ • Access to members-only Online critical reviews ex p. date: ____________ information on our website, • Complimentary CD, Herbal (Please include rhe 3-digir number fo ll owing rhe www.herbalgram.org Medicine: Expanded account # on signature line on back of card.) • HerbaiGram archives Commission E Monographs ($39 value) • Complete German 0 Send invoice to the address below Commission E Professional - $150 0 Check enclosed Monographs All Academic membership 0 Do not soli cit or share my contact info • Herbal Medicine: benefits, plus: Expanded Commission E • SO% discount on first order of 0 Please send me e-mail alens Monographs ABC publications from our • Botanical Booklets Herbal Education Catalog name • Herb Reference Guide • Membership certificate • Common Herbs Pamphlet Organization - $250 company • Free 1/2 hour research All Professional membership session with our education benefits, plus: profession/title department • 1 additional subscription to • 40% discount on additional our highly acclaimed journal phone fax research from our education Herba/Gram department • 3 user logins to members­ • One complimentary book, only information on our address Echinacea: The Immune website, www.herbalgram.org Herb by C. Hobbs • 10% discount on publications from our Herbal Education city stare/province Catalog • Membership card zip/postal code Corporate and Sponsorship co untry Small to large organizations can receive additional benefits, including the bi-weekly HerbCiip service, and also extend their support to ABC's mission through Corporate or Sponsor level membership. To learn more, please contact Wayne Silverman, PhD, at e-mail [email protected], or 800/373-71 OS x120. Advisory Board Each issue of Herba/Gram is peer reviewed by members of our Advisory Board and other qualified experts before publication. dear Cindy K. An gerhofer, Ph.D. Paul Alan Cox, Ph .D. Director of Botanical Research, Director, National Tropical Botanical Aveda Institute, Ga rd en, Ka uai, Hawaii reader Minneapolis, Minnesota Lyle E. Craker, Ph.D. John Thor Arnason, Ph.D. Professor, Departme nt of Pl ant and }\. virtual barrage of U.S. Food and Drug Administration (FDA) Professor of Biology, Department of Soil Sciences, University of Biology, University of Ottawa, Massachusetts, Amherst ..l"\.activity in the area of herbs and dietary supplements (DS) has kept both agency and industry extremely busy in the past six months. Ontario, Canada Edward M. Croom, Jr., Ph.D. In December 2002 the FDA announced a new "Consumer Health Dennis V. C. Awang, Ph .D., Scientific and Regulatory Affairs F.C. I. C. Manager, lndena USA East, Inc., Information Initiative" to implement regulations on claims for supple­ MediPiant Natural Products Oxford, Mississippi ments under the Dietary Supplement Health and Education Act of Consulting Services, White Rock, B.C., Wade Davis, Ph.D. 1994 (DSHEA), a move almost universally welcomed. FDA's new Canada Author, ethnobotanist, commissioner, Mark McClellan, M.D., Ph.D., a physician and econo­ Manuel F. Balandrin, R.Ph., Washington, D.C. mist, appears to be guiding the age ncy to work more effectively. Since Ph.D. Steven Dentali, Ph.D. January, the FDA has launched a trio of major initiatives: implementa­ Resea rch Scientist, NPS Vice President of Scientificand tion of the Bioterrorism Act, new label warnings for ephedra products, Pharmaceuticals, Salt Lake City, Utah Technical Affairs, American Herbal and proposed Good Manufacturing Practi ces. Bruce Barrett, M. D., Ph.D. Products Association, Silver Spring, The Bioterrorism Act and its FDA rules are Assistant Professor of Family Maryland part of the Bush Administration's War on Terror. Medicine, University ofWisconsin ­ Hardy Eshbaugh, Ph.D The Bioterrorism Act impacts aLl foodstuffs Madison Medical School Professor of Botany & Assistant imported into the United States, including Marilyn Barrett, Ph.D. Cu rator, Willard Sherman Turrell herbal materi als for teas and dietary supple­ Pharmacognosy Consulting Service, Herba riu m, Miami University, ments. In this issue, Washington regulatory San Carlos, California Oxford, Ohio attorney Paul Rubin provides an in-depth look at Bradley C. Bennett, Ph.D. Ad ri ane Fugh-Berman, M. D. the ramifications on the industry and, eventually, Associate Professor of Biology, Florida Author, Assistant Clinical Professor, the consumer. International University, Miami George Washington University In February, about three weeks after the death Joseph M. Betz, Ph.D. School of Medicine, Washing ton, DC of Baltimore Orioles pitcher Steve Bechler from Director of the Dietary Supplements Joe Graedon, M.S. Methods and Reference Materials Author, syndicated colum nist, radio an ephedra-rel ated case of heatstroke, FDA proposed warnings for Program, Office of Dietary host, Durham, North Carol ina supplements that contain ephedra. Stern "black
Load more

Recommended publications
  • Anti-Inflammatory Activity of Compounds from Kaempferia Marginata Rhizomes
    Songklanakarin J. Sci. Technol. 39 (1), 91-99, Jan. - Feb. 2017 http://www.sjst.psu.ac.th Original Article Anti-inflammatory activity of compounds from Kaempferia marginata rhizomes Kanidta Kaewkroek1, Chatchai Wattanapiromsakul1, 2, Hisashi Matsuda3, Seikou Nakamura3, and Supinya Tewtrakul1, 2* 1 Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand 2 Excellent Research Laboratory, Phytomedicine and Phamaceutical Biotechnology Excellence Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand 3 Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412 Japan Received: 12 January 2016; Revised: 12 April 2016; Accepted: 19 April 2016 Abstract Two new pimarane diterpenes were obtained from Kaempferia marginata rhizomes, which are 1-acetoxysandara- copimaradien-2-one (1) and 1-acetoxysandaracopimaradiene (4), along with seven known compounds from the hexane and chloroform fractions including two pimarane-type diterpenes [marginatol (5), sandaracopimaradiene (8)], one kavalactone [desmethoxyyangonin (3)], three steroids [sitosterol--D-glucoside (2), the mixture of stigmasterol and -sitosterol (6 + 7)] and one diarylheptanoid [bisdemethoxycurcumin (9)]. Compounds 3 and 9 exhibited potent effect against NO production with IC50 of 10.1 and 6.8 µM, respectively. Compound 3 inhibited iNOS mRNA expression in a dose-dependent manner, while 9 suppressed both of iNOS and COX-2 genes. Moreover, compounds 2, 3, 6 + 7 and 9 were isolated for the first time from K. marginata. These results revealed that diterpenes, diarylheptanoid and kavalactone are components of K. marginata that afford anti-inflammatory effect through a mechanism involving a decrease in inflammatory mediators. Keywords: Kaempferia marginata, diterpenes, diarylheptanoid, kavalactone, anti-inflammatory activity 1.
    [Show full text]
  • Herbal Insomnia Medications That Target Gabaergic Systems: a Review of the Psychopharmacological Evidence
    Send Orders for Reprints to [email protected] Current Neuropharmacology, 2014, 12, 000-000 1 Herbal Insomnia Medications that Target GABAergic Systems: A Review of the Psychopharmacological Evidence Yuan Shia, Jing-Wen Donga, Jiang-He Zhaob, Li-Na Tanga and Jian-Jun Zhanga,* aState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China; bDepartment of Pharmacology, School of Marine, Shandong University, Weihai, P.R. China Abstract: Insomnia is a common sleep disorder which is prevalent in women and the elderly. Current insomnia drugs mainly target the -aminobutyric acid (GABA) receptor, melatonin receptor, histamine receptor, orexin, and serotonin receptor. GABAA receptor modulators are ordinarily used to manage insomnia, but they are known to affect sleep maintenance, including residual effects, tolerance, and dependence. In an effort to discover new drugs that relieve insomnia symptoms while avoiding side effects, numerous studies focusing on the neurotransmitter GABA and herbal medicines have been conducted. Traditional herbal medicines, such as Piper methysticum and the seed of Zizyphus jujuba Mill var. spinosa, have been widely reported to improve sleep and other mental disorders. These herbal medicines have been applied for many years in folk medicine, and extracts of these medicines have been used to study their pharmacological actions and mechanisms. Although effective and relatively safe, natural plant products have some side effects, such as hepatotoxicity and skin reactions effects of Piper methysticum. In addition, there are insufficient evidences to certify the safety of most traditional herbal medicine. In this review, we provide an overview of the current state of knowledge regarding a variety of natural plant products that are commonly used to treat insomnia to facilitate future studies.
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2010/0311593 A1 Fischer Et Al
    US 20100311593A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2010/0311593 A1 Fischer et al. (43) Pub. Date: Dec. 9, 2010 (54) HALOALKYLMETHYLENEOXYPHENYL- AOIPI3/00 (2006.01) SUBSTITUTED KETOENOLS C07D 207/00 (2006.01) C07D 305/12 (2006.01) (75) Inventors: Reiner Fischer, Monheim (DE): CD7C 49/00 (2006.01) Thomas Bretschneider, Lohmar C07D 23/00 (2006.01) (DE); Stefan Lehr, Liederbach C07C 229/00 (2006.01) (DE); Eva-Maria Franken, Lyon C07C 69/76 (2006.01) (FR): Olga Malsam, Rosrath (DE); CD7C 24I/00 (2006.01) Arnd Voerste, Koln (DE); Ulrich CD7C 63/04 (2006.01) Görgens, Ratingen (DE); Jan (52) U.S. Cl. ......... 504/219;564/170; 514/622:504/336; Dittgen, Frankfurt (DE); Dieter Feucht, Eschborn (DE); Isolde 504/236; 514/248; 544/235; 540/545; 514/211.08; Hauser-Hahn, Leverkusen (DE); 548/544; 549/319; 568/379: 548/366.4; 560/37; Christopher Hugh Rosinger, 560/76; 560/105:564/149; 562/493 Hofheim (DE); Alfred Angermann, Kriftel (DE) (57) ABSTRACT The invention relates to novel compounds of the formula (I), Correspondence Address: STERNE, KESSLER, GOLDSTEIN & FOX P.L. L.C. (I) 1100 NEW YORKAVENUE, N.W. WASHINGTON, DC 20005 (US) (73) Assignee: Bayer Cropscience AG, Monheim (DE) (21) Appl. No.: 12/639,536 (22) Filed: Mar. 11, 2010 in which W, X, Y, Z and CKE are each as defined above, to several methods and intermediates for preparation thereof (30) Foreign Application Priority Data and to the use thereofas pesticides and/or herbicides. The invention also relates to selective herbicidal composi Mar.
    [Show full text]
  • Kava - the Unfolding Story: Report on a Work-In-Progress
    Article Kava - the unfolding story: Report on a work-in-progress. Denham, Alison, McIntyre, Michael and Whitehouse, Jule Available at http://clok.uclan.ac.uk/9455/ Denham, Alison, McIntyre, Michael and Whitehouse, Jule Kava - the unfolding story: Report on a work-in-progress. Journal of Alternative and Complementary Medicine, 8 (3). pp. 237-263. It is advisable to refer to the publisher’s version if you intend to cite from the work. For more information about UCLan’s research in this area go to http://www.uclan.ac.uk/researchgroups/ and search for <name of research Group>. For information about Research generally at UCLan please go to http://www.uclan.ac.uk/research/ All outputs in CLoK are protected by Intellectual Property Rights law, including Copyright law. Copyright, IPR and Moral Rights for the works on this site are retained by the individual authors and/or other copyright owners. Terms and conditions for use of this material are defined in the policies page. CLoK Central Lancashire online Knowledge www.clok.uclan.ac.uk THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 8, Number 3, 2002, pp. 237–263 © Mary Ann Liebert, Inc. SPECIAL REPORT Kava—the Unfolding Story: Report on a Work-in-Progress ALISON DENHAM, B.A. (Soc.), M.N.I.M.H., 1 MICHAEL McINTYRE, M.A., F.N.I.M.H., F.R.C.H.M., M.B.Ac.C., 2 and JULIE WHITEHOUSE, Ph.D., M.N.I.M.H. 3 ABSTRACT This paper, originated as a submission (now updated) to the U.K. Medicines Control Agency and Committee of Safety of Medicines (CSM) on January 11, 2002, in response to a report circu- lated by the German Federal Institute for Drugs and Medical Products (German initials are BfArM), a compilation of which is summarized in Appendix 2.
    [Show full text]
  • Kava Kava Extract Is Available from Ashland Chemical Co., Mini Star International, Inc., and QBI (Quality Botanical Ingredients, Inc.)
    SUMMARY OF DATA FOR CHEMICAL SELECTION Kava Kava 9000-38-8; 84696-40-2 November 1998 TABLE OF CONTENTS Basis for Nomination Chemical Identification Production Information Use Pattern Human Exposure Regulatory Status Evidence for Possible Carcinogenic Activity Human Data Animal Data Metabolism Other Biological Effects Structure-Activity Relationships References BASIS OF NOMINATION TO THE CSWG Kava kava is brought to the attention of the CSWG because it is a rapidly growing, highly used dietary supplement introduced into the mainstream U.S. market relatively recently. Through this use, millions of consumers using antianxiety preparations are potentially exposed to kava kava. A traditional beverage of various Pacific Basin countries, kava clearly has psychoactive properties. The effects of its long-term consumption have not been documented adequately; preliminary studies suggest possibly serious organ system effects. The potential carcinogenicity of kava and its principal constituents are unknown. INPUT FROM GOVERNMENT AGENCIES/INDUSTRY The U.S. Pharmacopeia is in the process of reviewing kava kava. No decision on preparation of a monograph has been made. SELECTION STATUS ACTION BY CSWG: 12/14/98 Studies requested: - Toxicological evaluation, to include studies of reproductive toxicity and neurotoxicity - Genotoxicity Priority: High Rationale/Remarks: - Significant human exposure - Leading dietary supplement with rapidly growing use - Concern that kava has been promoted as a substitute for ritilin in children - Test extract standardized to 30 percent kavalactones - NCI is conducting studies in Salmonella typhimurium CHEMICAL IDENTIFICATION CAS Registry Number: 9000-38-8 Kava-kava resin (8CI) Chemical Abstract Service Name: 84696-40-2 CAS Registry Number: Pepper (Piper), P. methysticum, ext. Chemical Abstract Service Name: Extract of kava; kava extract; Piper Synonyms and Trade Names: methisticum extract Description: The tropical shrub Piper methysticum is widely cultivated in the South Pacific.
    [Show full text]
  • A Review of the Literature
    Pharmacogn J. 2019; 11(6)Suppl:1511-1525 A Multifaceted Journal in the field of Natural Products and Pharmacognosy Original Article www.phcogj.com Phytochemical and Pharmacological Support for the Traditional Uses of Zingiberacea Species in Suriname - A Review of the Literature Dennis RA Mans*, Meryll Djotaroeno, Priscilla Friperson, Jennifer Pawirodihardjo ABSTRACT The Zingiberacea or ginger family is a family of flowering plants comprising roughly 1,600 species of aromatic perennial herbs with creeping horizontal or tuberous rhizomes divided into about 50 genera. The Zingiberaceae are distributed throughout tropical Africa, Asia, and the Americas. Many members are economically important as spices, ornamentals, cosmetics, Dennis RA Mans*, Meryll traditional medicines, and/or ingredients of religious rituals. One of the most prominent Djotaroeno, Priscilla Friperson, characteristics of this plant family is the presence of essential oils in particularly the rhizomes Jennifer Pawirodihardjo but in some cases also the leaves and other parts of the plant. The essential oils are in general Department of Pharmacology, Faculty of made up of a variety of, among others, terpenoid and phenolic compounds with important Medical Sciences, Anton de Kom University of biological activities. The Republic of Suriname (South America) is well-known for its ethnic and Suriname, Paramaribo, SURINAME. cultural diversity as well as its extensive ethnopharmacological knowledge and unique plant Correspondence biodiversity. This paper first presents some general information on the Zingiberacea family, subsequently provides some background about Suriname and the Zingiberacea species in the Dennis RA Mans country, then extensively addresses the traditional uses of one representative of the seven Department of Pharmacology, Faculty of Medical Sciences, Anton de Kom genera in the country and provides the phytochemical and pharmacological support for these University of Suriname, Kernkampweg 6, uses, and concludes with a critical appraisal of the medicinal values of these plants.
    [Show full text]
  • What I Do As a Yoga Therapist & Other Highlights from the 3Rd Annual Symposium on Yoga Therapy and Research • Meeting of Schools • Response to Keynote Address
    THE INTERNAT I O N A L A S S O C I ATION OF Y O G A T H E R A P I S T S YYoo gg aa T h e r a p y Too dd aa yy June 2009 Volume 5, Issue 2 What I Do as a Yoga Therapist & Other Highlights from the 3rd Annual Symposium on Yoga Therapy and Research • Meeting of Schools • Response to Keynote Address I am an Israeli Yogini Yoga Meets Mainstream Creating a Boutique Mental Health Yoga Studio 1 Yo g aT h e r a p yToday M a rch 2009 Ta b l e O fC o n t e n t s June 2009 Feature Section 15 SYTAR: Pre to Post 15 IAYT's Third Annual Symposium on Yoga Therapy and Research brought to life current research, practices and views on Yoga therapy. In this section you will find articles on a landmark meeting of schools; a sampling of what the Common Interest Community presentations were like; an overview of the general session presentation “As a Yoga Therapist, This Is What I Do;” and a response by Marshall Hagins, PT, PhD to Dr. Timothy McCall’s keynote address. onPractice 5 I am an Israeli Yogini by Michal Yarkoni 5 7 Purnam: The Heart of Yoga Therapy by Stephanie Sisson, LICSW, ERYT onSeasonalPractices 9 Therapeutic Applications of Yoga Practices for Summer and Fall by Patricia Hansen, MA, ERYT OnEducation 11 Journey Into YogaRx and Healing 25 by Lea Kraemer, ERYT OnIntegrativeMedicine 25 Yoga Meets the Mental Health Mainstream by Julie Deife onMedia 27 How to Use Herbs, Nutrients & Yoga in Mental Health Care by Julie Deife onResearch 29 Summaries of Pilot Studies on Chronic Obstructive Pulmonary Disease 31 by Kelly McGonigal, PhD onBusiness 31 Creating a Boutique Yoga Studio by Kate Hillman onMembers 33 Charter Members IAYT Member School Program; Overview of Standards Development for Yoga Therapy Training Programs; and more Cover Photo: Eric Small, Iyengar teacher, Los Angeles.
    [Show full text]
  • Piper Methysticum)
    Journal of Student Research (2015) Volume 4, Issue 2: pp. 69-72 Research Article A Closer Look at the Risks vs. Benefits of Kava (Piper methysticum) Anan A. Husseina If you took a trip to Fiji, the locals would probably welcome you with a drink of Kava. For centuries, the indigenous people of the South Pacific Islands have used the roots of a plant known as Kava. Beyond the use of Kava as a psychoactive substance, it has been incorporated as a cultural drink that is used in many ceremonies. In the late 1990’s Kava use spread quickly in Western countries including Europe, North America, and Australia. It was used as a treatment for anxiety. But just as quickly as it spread, the enthusiasm for it faded, because it was banned or restricted in many Western countries following reports of liver toxicity. In the United States, the Food and Drug Administration’s (FDA) concern for safety prompted a request for more research on the substance. The issues of safety and efficacy remain more specifically whether the benefits of using Kava outweigh the risks. History Kava is a beverage made from the roots of the plant included alcohol, cocaine, tobacco, and heroin. The findings Piper methysticum, and has been used historically in the suggest that kava may reduce the craving associated with the South Pacific Islands as a ceremonial drink. Kava was aforementioned substances, which may make kava a great introduced in Europe around the 1700s by Captain James future candidate to help with addiction. 13 Cook and has since spread widely to Australia, Europe, and Although the mechanism of action is not clear, it is the United States.
    [Show full text]
  • Cover Next Page > Cover Next Page >
    cover next page > Cover title: The Psychopharmacology of Herbal Medicine : Plant Drugs That Alter Mind, Brain, and Behavior author: Spinella, Marcello. publisher: MIT Press isbn10 | asin: 0262692651 print isbn13: 9780262692656 ebook isbn13: 9780585386645 language: English subject Psychotropic drugs, Herbs--Therapeutic use, Psychopharmacology, Medicinal plants--Psychological aspects. publication date: 2001 lcc: RC483.S65 2001eb ddc: 615/.788 subject: Psychotropic drugs, Herbs--Therapeutic use, Psychopharmacology, Medicinal plants--Psychological aspects. cover next page > < previous page page_i next page > Page i The Psychopharmacology of Herbal Medicine < previous page page_i next page > cover next page > Cover title: The Psychopharmacology of Herbal Medicine : Plant Drugs That Alter Mind, Brain, and Behavior author: Spinella, Marcello. publisher: MIT Press isbn10 | asin: 0262692651 print isbn13: 9780262692656 ebook isbn13: 9780585386645 language: English subject Psychotropic drugs, Herbs--Therapeutic use, Psychopharmacology, Medicinal plants--Psychological aspects. publication date: 2001 lcc: RC483.S65 2001eb ddc: 615/.788 subject: Psychotropic drugs, Herbs--Therapeutic use, Psychopharmacology, Medicinal plants--Psychological aspects. cover next page > < previous page page_ii next page > Page ii This page intentionally left blank. < previous page page_ii next page > < previous page page_iii next page > Page iii The Psychopharmacology of Herbal Medicine Plant Drugs That Alter Mind, Brain, and Behavior Marcello Spinella < previous page page_iii next page > < previous page page_iv next page > Page iv © 2001 Massachusetts Institute of Technology All rights reserved. No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from the publisher. This book was set in Adobe Sabon in QuarkXPress by Asco Typesetters, Hong Kong and was printed and bound in the United States of America.
    [Show full text]
  • Kavain Analogues As Potential Analgesic Agents
    Pharmacological Reports Copyright © 2012 2012, 64, 14191426 by Institute of Pharmacology ISSN 1734-1140 Polish Academy of Sciences Kavainanaloguesaspotentialanalgesicagents ElaineC.Kormann1,PatriciadeAguiarAmaral2,MicheleDavid3, VeraL.Eifler-Lima4,ValdirCechinelFilho1,FátimadeCamposBuzzi1 1 Chemical-PharmaceuticalInvestigationsCenter(NIQFAR)/CCS,UniversityofItajaíValey(UNIVALI),Itajaí/SC, Brazil 2 LaboratoryofMedicinalPlants(LaPlaM),UniversityoftheExtremeSouthofSantaCatarina(UNESC), Criciúma/SC,Brazil 3 LaboratoryofChemistryTherapeutic(UPRES4090),UniversityofRennes1,Rennes,France 4 LaboratoryofMedicinalOrganicSynthesis(LaSOM),FacultyofPharmacy,FederalUniversityofRioGrande doSul(UFRGS),PortoAlegre/RS,Brazil Correspondence: FátimadeCamposBuzzi,e-mail: [email protected]; VeraL.Eifler-Lima, e-mail: [email protected] Abstract: Background: Kavalactones are pharmacologically active compounds present in preparations of the root trunk of Piper methysticum Forst, known as kava. This work describes the analgesic activity of some synthesized analogues of synthetic kavain, which is the maincomponentofkava. Methods: The essays were initially performed against the writhing test in mice, and the most promising compound was analyzed us- ing other classical models of nociception, including formalin-, capsaicin-, glutamate-induced nociception, the hot plate test, and measurementofmotorperformance. Results: The results indicated that compound 6-(4-fluorophenyl)-4-methoxy-5,6-dihydropyran-2-one (2d) exerts potent and dose- dependent analgesic activity, inhibiting abdominal constrictions caused by acetic acid in mice, and being more active than some ref- erence drugs. It also presented activity in the other models of pain, with the exception of the hot plate test and the measurement of motorperformance. Conclusions: Although compound 2d exerts antinociceptive activity, the mechanism of action remains uncertain, but it does not in- volve the opioid system and does not appear to be associated with non-specific effects such as changes in locomotor activity or motor coordination.
    [Show full text]
  • Finalthesis Ana Ribeiro
    Are Classical Chinese Dietetics Functional Vegetative Foods? Ana Sofia Ferreira Ribeiro Dissertação de Mestrado em Medicina Tradicional Chinesa 2010 2 Ana Sofia Ferreira Ribeiro Are Classical Chinese Dietetics Functional Vegetative Foods? Dissertação de Candidatura ao grau de Mestre em Medicina Tradicional Chinesa submetida ao Instituto de Ciências Biomédicas de Abel Salazar da Universidade do Porto. Orientador – Doutor Frank Brazkiewicz Categoria – Medical Doctor of Integrated Medicine Afiliação – Heidelberg School of Chinese Medicine Co-orientador – Professor Joahnnes Greten Categoria – Medical Doctor of Integrated Medicine Afiliação – Heidelberg School of Chinese Medicine Co-orientador – Professor Jorge Machado Categoria – Professor Associado Afiliação – Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto. 3 4 Acknowledgments First of all I must acknowledge Prof. Greten who knows how to wonderfully teach and how to make you want to go further and further, it’s due to him, that I decided to go through with this Master. Dr. Frank, for being such an incredible support during this time, I know is agenda is always fully booked, but he would always have five minutes for me. Prof. Jorge Machado, who helped me all the way through, who always replied to my emails on time and was always there for my questions, that I must say where quite a few. To all my family who accepted all my complaints, my excuses and always gave me support and confidence to keep me going, and especially to my fiancé who sometimes was jealous of my work, but who always accepted my long hours in front of the computer . And finally to my manager and my colleagues who gave me as much support as they could, and allowed me to multitask when working, so I could finish on time.
    [Show full text]
  • Assessment Report on Piper Methysticum G. Forst., Rhizoma Based on Article 10A of Directive 2001/83/EC (Well-Established Use)
    22 November 2016 EMA/HMPC/450589/2016 Committee on Herbal Medicinal Products (HMPC) Assessment report on Piper methysticum G. Forst., rhizoma Based on Article 10a of Directive 2001/83/EC (well-established use) Based on Article 16d(1), Article 16f and Article 16h of Directive 2001/83/EC (traditional use) Draft Herbal substance(s) (binomial scientific name of the plant, including plant part) Piper methysticum G. Forst., rhizoma Herbal preparation(s) Not applicable Pharmaceutical form(s) Not applicable Rapporteur C. Purdel Peer-reviewer O. Palomino Note: This draft assessment report is published to support the public consultation of the draft public statement on Piper methysticum, rhizoma. It is a working document, not yet edited, and shall be further developed after the release for consultation of the public statement. Interested parties are welcome to submit comments to the HMPC secretariat, which will be taken into consideration but no ‘overview of comments received during the public consultation’ will be prepared on comments that will be received on this assessment report. The publication of this draft assessment report has been agreed to facilitate the understanding by Interested Parties of the assessment that has been carried out so far and led to the preparation of the draft public statement. 30 Churchill Place ● Canary Wharf ● London E14 5EU ● United Kingdom Telephone +44 (0)20 3660 6000 Facsimile +44 (0)20 3660 5555 Send a question via our website www.ema.europa.eu/contact An agency of the European Union © European Medicines Agency, 2016. Reproduction is authorised provided the source is acknowledged. Table of contents Table of contents ..................................................................................................................
    [Show full text]