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Forest Farming
Forest Farming Ken Mudge CY ROSE N NA Many sections of the Northeast have been reforested over the past century. Extensive forest cover is seen in this view from Wachu- sett Mountain in central Massachusetts. armers harvest crops from their fields, and agroforestry—a multidisciplinary approach to loggers harvest trees from their forests, agricultural production that achieves diverse, Fbut what do forest farmers harvest? The profitable, sustainable land use by integrating answer is an eclectic collection of non-timber trees with non-timber forest crops. forest crops like maple syrup, medicinal herbs, While some other agroforestry practices begin fruits, gourmet mushrooms, and nuts. with planting young trees that take years to Forest farming is an approach to forest man- mature, forest farming involves planting non- agement that combines some of the manage- timber forest crops beneath the canopy of an ment practices of conventional forestry with established forest. In other words, other agro- those of farming or gardening to achieve forestry practices bring the forest to the crops, an environmentally and economically sus- whereas forest farming brings the crops to the tainable land-use system. It is one of several forest. In this regard it is helpful to consider related practices that fall under the domain of the role of forest farming in overall forest man- Forest Farming 27 agement. A forest farm should be designed to bearing trees including walnuts and peaches, emulate as much as possible a natural forest. but there is no evidence of deliberate culti- This includes characteristics of a healthy forest vation of useful crops beneath the canopy of ecosystem such as species diversity, resilience established forest. -
Docket No. Fda–2011–N–0921
DOCKET NO. FDA–2011–N–0921 BEFORE THE UNITED STATES OF AMERICA DEPARTMENT OF HEALTH AND HUMAN SERVICES FOOD AND DRUG ADMINISTRATION COMMENTS OF THE AMERICAN HERBAL PRODUCTS ASSOCIATION ON PROPOSED RULE for STANDARDS FOR THE GROWING, HARVESTING, PACKING, AND HOLDING OF PRODUCE FOR HUMAN CONSUMPTION November 22, 2013 Docket No. FDA–2011–N–0921 November 22, 2013 Prefatory remarks ................................................................................................................................ 1 1. The broad and deep impact of the new regulations necessitates regulatory restraint ...................... 2 2. The same controls are neither necessary nor appropriate for non‐RTE foods as for RTE foods ......... 3 3. Wherever possible, food processors rather than farmers should ensure the biological safety of food ..................................................................................................................................................... 7 3.1 Wherever possible, FDA should avoid burdening farmers and should rely on food processors rather than farmers to ensure biological safety ................................................................................ 7 3.2 Farmers are generally ill‐equipped to comply with either Part 112 or 117 ................................. 7 3.3 Food processors are the appropriate entity to ensure the biological safety of food wherever possible ........................................................................................................................................... -
Anti-Inflammatory Activity of Compounds from Kaempferia Marginata Rhizomes
Songklanakarin J. Sci. Technol. 39 (1), 91-99, Jan. - Feb. 2017 http://www.sjst.psu.ac.th Original Article Anti-inflammatory activity of compounds from Kaempferia marginata rhizomes Kanidta Kaewkroek1, Chatchai Wattanapiromsakul1, 2, Hisashi Matsuda3, Seikou Nakamura3, and Supinya Tewtrakul1, 2* 1 Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand 2 Excellent Research Laboratory, Phytomedicine and Phamaceutical Biotechnology Excellence Center, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat Yai, Songkhla, 90112 Thailand 3 Kyoto Pharmaceutical University, Misasagi, Yamashina-ku, Kyoto, 607-8412 Japan Received: 12 January 2016; Revised: 12 April 2016; Accepted: 19 April 2016 Abstract Two new pimarane diterpenes were obtained from Kaempferia marginata rhizomes, which are 1-acetoxysandara- copimaradien-2-one (1) and 1-acetoxysandaracopimaradiene (4), along with seven known compounds from the hexane and chloroform fractions including two pimarane-type diterpenes [marginatol (5), sandaracopimaradiene (8)], one kavalactone [desmethoxyyangonin (3)], three steroids [sitosterol--D-glucoside (2), the mixture of stigmasterol and -sitosterol (6 + 7)] and one diarylheptanoid [bisdemethoxycurcumin (9)]. Compounds 3 and 9 exhibited potent effect against NO production with IC50 of 10.1 and 6.8 µM, respectively. Compound 3 inhibited iNOS mRNA expression in a dose-dependent manner, while 9 suppressed both of iNOS and COX-2 genes. Moreover, compounds 2, 3, 6 + 7 and 9 were isolated for the first time from K. marginata. These results revealed that diterpenes, diarylheptanoid and kavalactone are components of K. marginata that afford anti-inflammatory effect through a mechanism involving a decrease in inflammatory mediators. Keywords: Kaempferia marginata, diterpenes, diarylheptanoid, kavalactone, anti-inflammatory activity 1. -
Herbal Insomnia Medications That Target Gabaergic Systems: a Review of the Psychopharmacological Evidence
Send Orders for Reprints to [email protected] Current Neuropharmacology, 2014, 12, 000-000 1 Herbal Insomnia Medications that Target GABAergic Systems: A Review of the Psychopharmacological Evidence Yuan Shia, Jing-Wen Donga, Jiang-He Zhaob, Li-Na Tanga and Jian-Jun Zhanga,* aState Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P.R. China; bDepartment of Pharmacology, School of Marine, Shandong University, Weihai, P.R. China Abstract: Insomnia is a common sleep disorder which is prevalent in women and the elderly. Current insomnia drugs mainly target the -aminobutyric acid (GABA) receptor, melatonin receptor, histamine receptor, orexin, and serotonin receptor. GABAA receptor modulators are ordinarily used to manage insomnia, but they are known to affect sleep maintenance, including residual effects, tolerance, and dependence. In an effort to discover new drugs that relieve insomnia symptoms while avoiding side effects, numerous studies focusing on the neurotransmitter GABA and herbal medicines have been conducted. Traditional herbal medicines, such as Piper methysticum and the seed of Zizyphus jujuba Mill var. spinosa, have been widely reported to improve sleep and other mental disorders. These herbal medicines have been applied for many years in folk medicine, and extracts of these medicines have been used to study their pharmacological actions and mechanisms. Although effective and relatively safe, natural plant products have some side effects, such as hepatotoxicity and skin reactions effects of Piper methysticum. In addition, there are insufficient evidences to certify the safety of most traditional herbal medicine. In this review, we provide an overview of the current state of knowledge regarding a variety of natural plant products that are commonly used to treat insomnia to facilitate future studies. -
Special Forest Products
United States Department of Agriculture SPECIAL FOREST PRODUCTS Forest Service Species Information Guide Pacific Northwest Research Station for the Pacific Northwest General Technical Report PNW-GTR-513 Nan C. Vance, Melissa Borsting, David Pilz, and September 2001 Jim Freed Authors Nan C. Vance is a principle plant physiologist, and David Pilz is a botanist, For- estry Sciences Laboratory, 3200 SW Jefferson Way, Corvallis, OR 97331; Melissa Borsting is a graduate student, College of Forest Resources, University of Wash- ington, Box 352100, Seattle, WA 98195; and Jim Freed is an extension special forest products specialist, Washington State University, PO Box 4703, Olympia, WA 98504. Disclaimer This publication reports research and management information involving mush- room and plant harvesting. It neither recommends the use and ingestion of mush- rooms and plants nor implies that using wild plants and mushrooms is without risks. CAUTION: Mushroom and wild plant consumption can pose a serious, even fatal, risk to humans. It is strongly recommended that you spend your first collecting season using field identification guides and collecting with an expert if you intend to collect wild plants or mushrooms to eat. Abstract Vance, Nan C.; Borsting, Melissa; Pilz, David; Freed, Jim. 2001. Special forest products: species information guide for the Pacific Northwest. Gen. Tech. Rep. PNW-GTR-513. Portland, OR: U.S. Department of Agriculture, Forest Service, Pacific Northwest Research Station. 169 p. This guide is a collection of information about economically important vascular and nonvascular plants and fungi found in the Pacific Northwest that furnish special forest products. Many of these plants and fungi are also found in Alaska, northern Idaho, and western Montana. -
NIH Public Access Author Manuscript Pharmacol Ther
NIH Public Access Author Manuscript Pharmacol Ther. Author manuscript; available in PMC 2010 August 1. NIH-PA Author ManuscriptPublished NIH-PA Author Manuscript in final edited NIH-PA Author Manuscript form as: Pharmacol Ther. 2009 August ; 123(2): 239±254. doi:10.1016/j.pharmthera.2009.04.002. Ethnobotany as a Pharmacological Research Tool and Recent Developments in CNS-active Natural Products from Ethnobotanical Sources Will C. McClatcheya,*, Gail B. Mahadyb, Bradley C. Bennettc, Laura Shielsa, and Valentina Savod a Department of Botany, University of Hawaìi at Manoa, Honolulu, HI 96822, U.S.A b Department of Pharmacy Practice, University of Illinois at Chicago, Chicago, IL 60612, U.S.A c Department of Biological Sciences, Florida International University, Miami, FL 33199, U.S.A d Dipartimento di Biologia dì Roma Trè, Viale Marconi, 446, 00146, Rome, Italy Abstract The science of ethnobotany is reviewed in light of its multidisciplinary contributions to natural product research for the development of pharmaceuticals and pharmacological tools. Some of the issues reviewed involve ethical and cultural perspectives of healthcare and medicinal plants. While these are not usually part of the discussion of pharmacology, cultural concerns potentially provide both challenges and insight for field and laboratory researchers. Plant evolutionary issues are also considered as they relate to development of plant chemistry and accessing this through ethnobotanical methods. The discussion includes presentation of a range of CNS-active medicinal plants that have been recently examined in the field, laboratory and/or clinic. Each of these plants is used to illustrate one or more aspects about the valuable roles of ethnobotany in pharmacological research. -
(12) Patent Application Publication (10) Pub. No.: US 2010/0311593 A1 Fischer Et Al
US 20100311593A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2010/0311593 A1 Fischer et al. (43) Pub. Date: Dec. 9, 2010 (54) HALOALKYLMETHYLENEOXYPHENYL- AOIPI3/00 (2006.01) SUBSTITUTED KETOENOLS C07D 207/00 (2006.01) C07D 305/12 (2006.01) (75) Inventors: Reiner Fischer, Monheim (DE): CD7C 49/00 (2006.01) Thomas Bretschneider, Lohmar C07D 23/00 (2006.01) (DE); Stefan Lehr, Liederbach C07C 229/00 (2006.01) (DE); Eva-Maria Franken, Lyon C07C 69/76 (2006.01) (FR): Olga Malsam, Rosrath (DE); CD7C 24I/00 (2006.01) Arnd Voerste, Koln (DE); Ulrich CD7C 63/04 (2006.01) Görgens, Ratingen (DE); Jan (52) U.S. Cl. ......... 504/219;564/170; 514/622:504/336; Dittgen, Frankfurt (DE); Dieter Feucht, Eschborn (DE); Isolde 504/236; 514/248; 544/235; 540/545; 514/211.08; Hauser-Hahn, Leverkusen (DE); 548/544; 549/319; 568/379: 548/366.4; 560/37; Christopher Hugh Rosinger, 560/76; 560/105:564/149; 562/493 Hofheim (DE); Alfred Angermann, Kriftel (DE) (57) ABSTRACT The invention relates to novel compounds of the formula (I), Correspondence Address: STERNE, KESSLER, GOLDSTEIN & FOX P.L. L.C. (I) 1100 NEW YORKAVENUE, N.W. WASHINGTON, DC 20005 (US) (73) Assignee: Bayer Cropscience AG, Monheim (DE) (21) Appl. No.: 12/639,536 (22) Filed: Mar. 11, 2010 in which W, X, Y, Z and CKE are each as defined above, to several methods and intermediates for preparation thereof (30) Foreign Application Priority Data and to the use thereofas pesticides and/or herbicides. The invention also relates to selective herbicidal composi Mar. -
Plant-Based Medicines for Anxiety Disorders, Part 2: a Review of Clinical Studies with Supporting Preclinical Evidence
CNS Drugs 2013; 24 (5) Review Article Running Header: Plant-Based Anxiolytic Psychopharmacology Plant-Based Medicines for Anxiety Disorders, Part 2: A Review of Clinical Studies with Supporting Preclinical Evidence Jerome Sarris,1,2 Erica McIntyre3 and David A. Camfield2 1 Department of Psychiatry, Faculty of Medicine, University of Melbourne, Richmond, VIC, Australia 2 The Centre for Human Psychopharmacology, Swinburne University of Technology, Melbourne, VIC, Australia 3 School of Psychology, Charles Sturt University, Wagga Wagga, NSW, Australia Correspondence: Jerome Sarris, Department of Psychiatry and The Melbourne Clinic, University of Melbourne, 2 Salisbury Street, Richmond, VIC 3121, Australia. Email: [email protected], Acknowledgements Dr Jerome Sarris is funded by an Australian National Health & Medical Research Council fellowship (NHMRC funding ID 628875), in a strategic partnership with The University of Melbourne, The Centre for Human Psychopharmacology at the Swinburne University of Technology. Jerome Sarris, Erica McIntyre and David A. Camfield have no conflicts of interest that are directly relevant to the content of this article. 1 Abstract Research in the area of herbal psychopharmacology has revealed a variety of promising medicines that may provide benefit in the treatment of general anxiety and specific anxiety disorders. However, a comprehensive review of plant-based anxiolytics has been absent to date. Thus, our aim was to provide a comprehensive narrative review of plant-based medicines that have clinical and/or preclinical evidence of anxiolytic activity. We present the article in two parts. In part one, we reviewed herbal medicines for which only preclinical investigations for anxiolytic activity have been performed. In this current article (part two), we review herbal medicines for which there have been both preclinical and clinical investigations for anxiolytic activity. -
Medicinal Plant Conservation
MEDICINAL Medicinal Plant PLANT SPECIALIST GROUP Conservation Silphion Volume 11 Newsletter of the Medicinal Plant Specialist Group of the IUCN Species Survival Commission Chaired by Danna J. Leaman Chair’s note . 2 Sustainable sourcing of Arnica montana in the International Standard for Sustainable Wild Col- Apuseni Mountains (Romania): A field project lection of Medicinal and Aromatic Plants – Wolfgang Kathe . 27 (ISSC-MAP) – Danna Leaman . 4 Rhodiola rosea L., from wild collection to field production – Bertalan Galambosi . 31 Regional File Conservation data sheet Ginseng – Dagmar Iracambi Medicinal Plants Project in Minas Gerais Lange . 35 (Brazil) and the International Standard for Sus- tainable Wild Collection of Medicinal and Aro- Conferences and Meetings matic Plants (ISSC-MAP) – Eleanor Coming up – Natalie Hofbauer. 38 Gallia & Karen Franz . 6 CITES News – Uwe Schippmann . 38 Conservation aspects of Aconitum species in the Himalayas with special reference to Uttaran- Recent Events chal (India) – Niranjan Chandra Shah . 9 Conservation Assessment and Management Prior- Promoting the cultivation of medicinal plants in itisation (CAMP) for wild medicinal plants of Uttaranchal, India – Ghayur Alam & Petra North-East India – D.K. Ved, G.A. Kinhal, K. van de Kop . 15 Ravikumar, R. Vijaya Sankar & K. Haridasan . 40 Taxon File Notices of Publication . 45 Trade in East African Aloes – Sara Oldfield . 19 Towards a standardization of biological sustain- List of Members. 48 ability: Wildcrafting Rhatany (Krameria lap- pacea) in Peru – Maximilian -
Rhodiola Rosea L
u Ottawa l.'Univcrsilc! cnnnrlicwu- Cnnodn's univcrsiiy FACULTE DES ETUDES SUPERIEURES ls=l FACULTY OF GRADUATE AND ET POSTOCTORALES U Ottawa POSDOCTORAL STUDIES L*University canadiennc Canada's university Vicky J. Filion AUTEUR DETATHISET/ AUTHOR OF THESIS" M_.Sc. (Biology) GRADE/DEGREE Department of Biology TAMTE"TCOLirDpARTEMENT~^ACUITY, S*CHOdi~DEWRTMENT" A Novel Phytochemical and Ecological Study of the Nunavik Medicinal Plant Rhodiola rosea L. TITRE DE LA THESE / TITLE OF THESIS _____„„____Dr._ J. Arnason A. Cuerrier EXAMINATEURS (EXAMINATRICES) DE LA THESE / THESIS EXAMINERS Dr. C. Charest Dr. J. Kerr Dr. N. Cappuccino _Garjr\V^SJatCT_ Le Doyen de la Faculte des etudes superieures et postdoctorales I Dean of the Faculty of Graduate and Postdoctoral Studies A Novel Phytochemical and Ecological Study of the Nunavik Medicinal Plant Rhodiola rosea L. Vicky J. Filion Thesis submitted to the Faculty of Graduate and Postdoctoral Studies University of Ottawa in partial fulfillment of the requirements for the M.Sc. degree in the Ottawa-Carleton Institute of Biology These soumise a la Faculte des etudes superieures et postdoctorales Universite d'Ottawa en vue de l'obtention de la maitrise es sciences Institut de biologie d'Ottawa-Carleton © Vicky J. Filion, Ottawa, Canada, 2008 Library and Bibliotheque et 1*1 Archives Canada Archives Canada Published Heritage Direction du Branch Patrimoine de I'edition 395 Wellington Street 395, rue Wellington Ottawa ON K1A0N4 Ottawa ON K1A0N4 Canada Canada Your file Votre reference ISBN: 978-0-494-50879-4 -
Kava - the Unfolding Story: Report on a Work-In-Progress
Article Kava - the unfolding story: Report on a work-in-progress. Denham, Alison, McIntyre, Michael and Whitehouse, Jule Available at http://clok.uclan.ac.uk/9455/ Denham, Alison, McIntyre, Michael and Whitehouse, Jule Kava - the unfolding story: Report on a work-in-progress. Journal of Alternative and Complementary Medicine, 8 (3). pp. 237-263. It is advisable to refer to the publisher’s version if you intend to cite from the work. For more information about UCLan’s research in this area go to http://www.uclan.ac.uk/researchgroups/ and search for <name of research Group>. For information about Research generally at UCLan please go to http://www.uclan.ac.uk/research/ All outputs in CLoK are protected by Intellectual Property Rights law, including Copyright law. Copyright, IPR and Moral Rights for the works on this site are retained by the individual authors and/or other copyright owners. Terms and conditions for use of this material are defined in the policies page. CLoK Central Lancashire online Knowledge www.clok.uclan.ac.uk THE JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE Volume 8, Number 3, 2002, pp. 237–263 © Mary Ann Liebert, Inc. SPECIAL REPORT Kava—the Unfolding Story: Report on a Work-in-Progress ALISON DENHAM, B.A. (Soc.), M.N.I.M.H., 1 MICHAEL McINTYRE, M.A., F.N.I.M.H., F.R.C.H.M., M.B.Ac.C., 2 and JULIE WHITEHOUSE, Ph.D., M.N.I.M.H. 3 ABSTRACT This paper, originated as a submission (now updated) to the U.K. Medicines Control Agency and Committee of Safety of Medicines (CSM) on January 11, 2002, in response to a report circu- lated by the German Federal Institute for Drugs and Medical Products (German initials are BfArM), a compilation of which is summarized in Appendix 2. -
Kava Kava Extract Is Available from Ashland Chemical Co., Mini Star International, Inc., and QBI (Quality Botanical Ingredients, Inc.)
SUMMARY OF DATA FOR CHEMICAL SELECTION Kava Kava 9000-38-8; 84696-40-2 November 1998 TABLE OF CONTENTS Basis for Nomination Chemical Identification Production Information Use Pattern Human Exposure Regulatory Status Evidence for Possible Carcinogenic Activity Human Data Animal Data Metabolism Other Biological Effects Structure-Activity Relationships References BASIS OF NOMINATION TO THE CSWG Kava kava is brought to the attention of the CSWG because it is a rapidly growing, highly used dietary supplement introduced into the mainstream U.S. market relatively recently. Through this use, millions of consumers using antianxiety preparations are potentially exposed to kava kava. A traditional beverage of various Pacific Basin countries, kava clearly has psychoactive properties. The effects of its long-term consumption have not been documented adequately; preliminary studies suggest possibly serious organ system effects. The potential carcinogenicity of kava and its principal constituents are unknown. INPUT FROM GOVERNMENT AGENCIES/INDUSTRY The U.S. Pharmacopeia is in the process of reviewing kava kava. No decision on preparation of a monograph has been made. SELECTION STATUS ACTION BY CSWG: 12/14/98 Studies requested: - Toxicological evaluation, to include studies of reproductive toxicity and neurotoxicity - Genotoxicity Priority: High Rationale/Remarks: - Significant human exposure - Leading dietary supplement with rapidly growing use - Concern that kava has been promoted as a substitute for ritilin in children - Test extract standardized to 30 percent kavalactones - NCI is conducting studies in Salmonella typhimurium CHEMICAL IDENTIFICATION CAS Registry Number: 9000-38-8 Kava-kava resin (8CI) Chemical Abstract Service Name: 84696-40-2 CAS Registry Number: Pepper (Piper), P. methysticum, ext. Chemical Abstract Service Name: Extract of kava; kava extract; Piper Synonyms and Trade Names: methisticum extract Description: The tropical shrub Piper methysticum is widely cultivated in the South Pacific.