University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Dissertations and Theses in Biological Sciences Biological Sciences, School of Spring 2-13-2014 FUNCTIONAL IMPLICATIONS OF THE BAF-B1 AXIS DURING THE VACCINIA VIRUS LIFE CYCLE Nouhou Ibrahim University of Nebraska-Lincoln,
[email protected] Follow this and additional works at: http://digitalcommons.unl.edu/bioscidiss Part of the Other Microbiology Commons, and the Virology Commons Ibrahim, Nouhou, "FUNCTIONAL IMPLICATIONS OF THE BAF-B1 AXIS DURING THE VACCINIA VIRUS LIFE CYCLE" (2014). Dissertations and Theses in Biological Sciences. 61. http://digitalcommons.unl.edu/bioscidiss/61 This Article is brought to you for free and open access by the Biological Sciences, School of at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Dissertations and Theses in Biological Sciences by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. FUNCTIONAL IMPLICATIONS OF THE BAF-B1 AXIS DURING THE VACCINIA VIRUS LIFE CYCLE by Nouhou Ibrahim A DISSERTATION Presented to the Faculty of The Graduate College at the University of Nebraska In Partial Fulfillment of Requirements For the Degree of Doctor of Philosophy Major: Biological Sciences (Microbiology and Molecular Biology) Under the Supervision of Professor Matthew S. Wiebe Lincoln, Nebraska May, 2014 FUNCTIONAL IMPLICATIONS OF THE BAF-B1 AXIS DURING THE VACCINIA VIRUS LIFE CYCLE Nouhou Ibrahim, MSc., Ph.D. University of Nebraska, 2014 Advisor: Matthew Wiebe Vaccinia virus is the prototypic member of the Poxviridae family, which includes variola virus, the agent of smallpox. Poxviruses encode their own transcriptional machinery and a set of proteins to evade the host defense system, and thus are able to replicate entirely in the cytoplasm of their host.