Risk Groups: Viruses (C) 1988, American Biological Safety Association

Home , Alphavirus, Animal virus, Aphthovirus, Arbovirus, Buffalopox, B virus

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Flaviviridae/ Flavivirus (Grp 2 Absettarov, TBE 4 4 4 implied 3 3 4 + B Arbovirus) Acute haemorrhagic taxonomy 2, Enterovirus 3 conjunctivitis virus Picornaviridae 2 + different 70 (AHC) Adenovirus 4 Adenoviridae 2 2 (incl animal) 2 2 + (human,all types) 5 Aino X-Arboviruses 6 Akabane X-Arboviruses 7 Alastrim Poxviridae Restricted 4 4, Foot-and- 8 Aphthovirus Picornaviridae 2 mouth disease + viruses 9 Araguari X-Arboviruses (feces of children 10 Astroviridae Astroviridae 2 2 + + and lambs) Avian leukosis virus 11 Viral vector/Animal retrovirus 1 3 (wild strain) + (ALV) 3, (Rous 12 Avian sarcoma virus Viral vector/Animal retrovirus 1 sarcoma virus, + RSV wild strain) 13 Baculovirus Viral vector/Animal virus 1 + Togaviridae/ Alphavirus (Grp 14 Barmah Forest 2 A Arbovirus) 15 Batama X-Arboviruses 16 Batken X-Arboviruses Togaviridae/ Alphavirus (Grp 17 Bebaru virus 2 2 2 2 + A Arbovirus) 18 Bhanja X-Arboviruses 19 Bimbo X-Arboviruses Blood-borne hepatitis 20 viruses not yet Unclassified viruses 2 implied 2 implied 3 (**)D 3 + identified 21 Bluetongue X-Arboviruses 22 Bobaya X-Arboviruses 23 Bobia X-Arboviruses Bovine 24 immunodeficiency Viral vector/Animal retrovirus 3 (wild strain) + virus (BIV) 3, Bovine Bovine leukemia 25 Viral vector/Animal retrovirus 1 lymphosarcoma + virus (BLV) virus wild strain Bovine papilloma Papovavirus/ Animal virus 26 1 2 + virus vector

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Bovine spongiform Unconventional agents, 27 2 3 + encephalopathy prions 28 Buenaventura X-Arboviruses Buffalopox virus: 2 29 viruses(1 a vaccinia Poxviridae 2 implied 2 2 implied 2 2 + + variant) Bunyaviridae/ Bunyavirus 30 Bunyamwera virus 2 2 2 2 2 + + Group Bunyaviridae/ Bunyavirus 31 Bunyavirus 2 Group 32 Cabassou X-Arboviruses 2 see arbovirus 33 Cache valley X-Arboviruses table 2 (incl California Bunyaviridae/ Bunyavirus 2 see arbovirus 3 human, 2 34 2 LaCrosse, 2 + + encephalitis virus Group table animal Lumbo and 35 Camel pox virus Poxviridae 2 implied 2 2 implied 3 + 2 36 Cardiovirus Picornaviridae 2 all isolates Encephalomyoc + arditis Group Central European Flaviviridae/ Flavivirus (Grp 37 Tick-borne 4 4 3 V (**) B Arbovirus) encephalitis Chick embryo lethal 38 Viral vector/Animal virus orphan CELO 2, high passage Togaviridae/ Alphavirus (Grp 3 arbovirus 3 (recent 39 Chikungunya virus strains;vaccine 3 arbovirus table 3 (**) 3 # + A Arbovirus) table isolates) strain131/25 40 Chim X-Arboviruses 41 Cocal X-Arboviruses 2 (including 42 Coltiviruses Reoviridae Colorado Tick 2 2 + + Fever) Congo Crimean 4 (Crimean- 43 haemorrhagic fever Bunyaviridae/ Nairoviruses 4 4 4 4 4 + Congo) TBE 2 (human, 44 Coronavirus Coronaviridae 2 2 2 human + + bovine) 45 Cowpox virus Poxviridae 2 V 2 2 implied 2 2 + + 2 ( Types A and 46 Coxsackie Picornoviridae/ Enterovirus 2 2 2 2 + B) Creutzfeldt-Jacob 47 Unconventional agents/prion 2 3 3 3 (**) D 3 2 C,G + disese

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Cytomegalovirus Herpesviridae/ 2 all isolates 48 (CMV) Genus 2 2 2 2 (HH5) 2 + Betaherpesviridae HHV5 Lymphocryptovirus Flaviviridae/ Flavivirus (Grp 49 Dengue virus Type 1-4 2 2 (types1-4), 3 2,Types 1-4 3, type 1-4 3 2 + B Arbovirus) 50 Dhori X-Arboviruses 3 arbovirus table 3 arbovirus 51 Dog sarcoma Viral vector/Animal virus 52 Dugbe X-Arboviruses Eastern equine Togaviridae/ Alphavirus (Grp 53 encephalomyelitis 2 V 2 V 3 3 V 3 3 + + A Arbovirus) (EEE) 54 Ebola virus Filoviridae 4 4 4 4 4 4 + + 55 Echoviruses Picornoviridae/ Enterovirus 2 2 2 2 2 + Ectromelia 56 Orthopoxvirus (mousepox) Elephantpox virus 57 Poxviridae 2 2 implied 2 2 + + (variant of cowpox) 58 Entero Picornoviridae/ Enterovirus 2 2 2, Epstein-Barr virus Herpesviridae/ 59 2 2 2 implied, HH4 2 2 Lymphocryptovi + (EBV) Gammaherpesviridae rus (EB-like) Togaviridae/ Alphavirus (Grp 3 arbovirus 60 Everglade virus 3 arbovirus table 3 (**) 3 + A Arbovirus) table Feline leukemia 61 Viral vector/Animal retrovirus 1 3 wild strain + virus, FeLV Feline sarcoma virus, 62 Viral vector/Animal retrovirus 1 3 wild strain + FeSV Flanders-Hart Park from mosquitoes 2 arbovirus 63 virus (see Zinsser, pg Rhabdoviridae and birds, no 2 arbovirus table table 777) human sx Herpesviridae / 64 Gammaherpes 3 Gammaherpesvirinae Ganjam (USDA 65 X-Arboviruses permit) 66 Garba X-Arboviruses 3 arbovirus table 3 arbovirus 3 see arbovirus 67 Germiston X-Arboviruses 3 table Gerstmann- Unconventional agents, 68 2 implied 3 implied 3 (**) D(d) 3 2 C,G + Straussler-Scheinker prions 69 Getah X-Arboviruses 3 arbovirus table 3 arbovirus Gibbon leukemia 70 Viral vector/Animal retrovirus 1 virus (GaLV) 71 Gordil X-Arboviruses 3 arbovirus table 3 arbovirus 72 Guanarito Arenaviruses 4 4 4 4 +

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII 73 Guaratuba X-Arboviruses 2 arbovirus table 2 arbovirus 74 Guinea pig herpes Viral vector/Animal virus 1 75 Hamster leukemia Viral vector/Animal virus 1 Hantaan (Korean see also sin 76 Bunyaviridae/ Hantaviruses 3 3 3 3 3 3 + haemorrhagic fever) nombre virus Flaviviridae/ Flavivirus (Grp 77 Hanzalova,TBE 4 4 4 implied 3 3 4 + B Arbovirus) Hart Park virus (see 2 arbovirus 78 Rhabdoviridae 2 arbovirus table Zinsser, pg 777) table 79 Hazara virus Bunyaviridae/ Nairoviruses 2 arbovirus table 2 arbovirus 2 2 4 + Hepatitis A virus, 2 all 80 human enterovirus Picornoviridae/ Hepatovirus 2 V 2 2 V 2 2 + hepatoviruses type 72 2 (includes 81 Hepatitis B virus Hepadnaviridae 2 V 2 3 (**)V,D 3 2,G.V + Delta Togaviridae/ (hepatitis non- 82 Hepatitis C 2 2 2 3(**),D 3 2 (unclassified) + Pestivirus(Canada) A,non-B) Delta, only Hepatitis D (Delta) 83 Hepadnaviridae pathogenic with 2 2 3(**)V, D 2 (unclassified) + virus HBV inf. 84 Hepatitis E virus Calciviridae 2 2 2 3(**) 3 2 + 85 Herpes saimiri Herpesviridae/ Rhadinovirus 3 2 + Herpes simplex Herpesviridae/ 2 (types 1 and 2 (HHV 1 and 2 ( types 1 and 86 Type 1 and 2 (EC) 2 2 2,E + viruses Alphaherpesviridae 2) 2) 2) 87 Herpesvirus ateles Herpesviridae/ Rhadinovirus 1 3 Herpesvirus saimiri, Herpesviridae/ Animal virus 88 1 Genus Rhadinovirus vector Herpesvirus simiae Herpesviridae/ 3 human, 2 89 3/4 4 4 3 4 (B virus) Alphaherpesviridae animal Herpesvirus zoster Herpesviridae/ 90 2 2 2 (VZV,HHV3) 2 2 2,E + (Varicella) Alphaherpesviridae Human B 2 (Herpes types 91 Herpesviridae HHV 6 2 (HBLV-HHV6) 2 + lymphotropic virus 6 and 7) Human Immunodeficiency 1, 2 (AIDS 3 ( Types 1 and 92 Retroviridae/ Lentiviridae 2/2+/3 2 or 3 3 (**)D 3 2 G, E + virus(HIV) Types 1 causing) 2) and 2 Oncornavirus Human T-cell Retroviridae/ Oncovirinae/ Types 1-3 (EC 1 3 (Types 1 and 3 (**)D,types 1 2,G,E Types I 93 lymphotropic viruses 2/3 3 3 + Genus Oncornavirus C and 2) 2) and 2 and II (HTLV) Flaviviridae/ Flavivirus (Grp 94 Hypr,TBE 4 4 4 implied 3 3 4 + B Arbovirus) 95 Ibaraki X-Arboviruses 3 arbovirus table 3 arbovirus

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII vaccine strains: Influenza virus 96 Orthomyxoviridae A/PR8/34, 1 (vaccine strain) A/WS/33 2 human, 3 Influenza virus,Types Types A,B, and C 2,V for Types 2,V recent 97 Orthomyxoviridae 2 2 (types A,B, C) 2 animal (types A, + + A-C (EC) A,B isolates B, C) 98 Inhangapi X-Arboviruses 3 arbovirus table 3 arbovirus 99 Inini X-Arboviruses 3 arbovirus table 3 arbovirus 100 Israel Turkey X-Arboviruses 3 arbovirus table 3 arbovirus 101 Issyk-Kul X-Arboviruses 3 arbovirus table 3 arbovirus 102 Itaituba X-Arboviruses 3 arbovirus table 3 arbovirus Japanese B Flaviviridae/Flavivirus (Grp B 3 arbovirus 103 3 arbovirus table 3 3 V 3 # 3 + encephalitis Arbovirus) table Japanese Flaviviridae/Flavivirus (Grp B 104 encephalitis, 2 + Arbovirus) Nakayama 105 Junin virus Arenaviruses 3V/4 4, 3 (v) 4 4 4 4 + 106 Kairi(x) X-Arboviruses i 3 arbovirus table 3 arbovirus 107 Khasan, Koutango X-Arboviruses 3 arbovirus table 3 arbovirus Flaviviridae/ Flavivirus (Grp 108 Kokobera B Arbovirus) Flaviviridae/ Flavivirus (Grp 109 Kumlinge,TBE I 4 4 4 implied 3 3 + B Arbovirus) Flaviviridae/ Flavivirus (Grp 2 arbovirus 110 Kunjin 2 arbovirus table 2 2 B Arbovirus) table 111 Kuru Unconventional agents/prion 2 3 3 3 (**) D (d) 3 2 C,G + Kyasanur Forest, Flaviviridae/ Flavivirus (Grp 112 4 4 4 3 (**) V 3 4 + + TBE B Arbovirus) 113 Kyzylagach X-Arboviruses 3 arbovirus table 3 arbovirus 114 LaCrosse virus X-Arboviruses 2 arbovirus table 2 arbovirus 115 Langat virus X-Arboviruses 2 arbovirus table 2 arbovirus 116 Lassa fever virus Arenaviruses 4 4 4 4 4 4 + Lentivirinae , except 117 Retroviridae 2 HIV-1 and HI Flaviviridae/ Flavivirus (Grp 3 arbovirus 118 Looping ill , TBE 3 arbovirus table 4 implied 3 (**) 3 + + B Arbovirus) table 119 Lucke (frog) virus Viral vector/Animal virus Lymphocytic 120 choriomeningitis Arenaviruses neurotropic strains 2/3 3 3 3, neurotropic 3 3 + + (neurotropic) virus Lymphocytic other 2,CDC- 121 choriomeningitis Arenaviruses viscerotrophic 2 2 2 2 + + viscerotrophic virus (Canada:lab 122 Machupo virus Arenaviruses 4 4 4 4 4 4 +

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII 123 Marburg virus Filoviridae 4 4 4 4 4 4 + + Herpesviridae/ Animal virus 124 Marek's disease virus 1 (vector) 3 (birds) + vector Mason- Pfizer 125 Viral vector/Animal retrovirus 1 monkey virus Togaviridae/ Alphavirus (Grp 3 arbovirus 126 Mayaro virus 3 arbovirus table 3 3 + A Arbovirus) table 127 Measles virus Paramyxoviridae/ 2 2 implied 2 V 2 2,V + 128 Middelburg X-Arboviruses 3 arbovirus table 3 arbovirus also 2 human, 3 129 Milker's node virus Poxviridae Pseudocowpox 2 implied 2 2 implied 2 + + animal virus Molluscum 130 Poxviridae 2 implied 2 2 implied 2 2 + contagiosum virus 131 Monkeypox virus Poxviridae/ Orthopoxvirus 2 V 3 4 3 V 3 3 + + Mopeia virus (and 3 arbovirus 132 other Tacaribe Arenaviruses 3 arbovirus table 2 3 4 + table viruses) Morbillivirus,except Paramyxoviridae/ 133 2 3 (EMV) + + Rinderpest Morbillivirus Mouse mammary 134 Viral vector/Animal retrovirus 1 tumor virus Togaviridae/ Alphavirus (Grp 3 arbovirus 135 Mucambo virus 3 arbovirus table 3 (**) 3 # + A Arbovirus) table Paramyxoviridae/ 136 Mumps virus 2 2 implied 2 V 2 2,V + Paramyxovirus Murine Herpesviridae/ Animal virus 137 1 cytomegalovirus vector 138 Murine leukemia Viral vector/Animal retrovirus 1 + 139 Murine sarcoma virus Viral vector/Animal retrovirus 1 3 wild strain + Murray Valley Flaviviridae/ Flavivirus (Grp (Australian 3 arbovirus 140 encephalitis(Australia 3 arbovirus table 3 3 3 2 + B Arbovirus) encephalitis) table encephalitis) Nairobi Sheep 141 Bunyaviridae/ Nairovirus USDA restricted 3 arbovirus table restricted 3 + + Disease 142 Nariva, Negishi, X-Arboviruses 3 arbovirus table 3 arbovirus Togaviridae/ Alphavirus (Grp 3 arbovirus 143 Ndumu 3 arbovirus table 3 3 + + A Arbovirus) table New Minto, 3 arbovirus 144 X-Arboviruses 3 arbovirus table Nodamura, Northway table Newcastle Disease Paramyxoviridae/ 2,nonvirulent 145 2 2 implied 2 virus Paramyxovirus endemic 146 Norwalk virus Calciviridae 2 implied 2 2 (unclassified) 2 2 +

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Togaviridae/ Alphavirus (Grp 2 arbovirus 147 O'Nyong-Nyong virus 2 arbovirus table 2 2 2 + A Arbovirus) table Omsk (hemorrhagic Flaviviridae/ Flavivirus (Grp 148 hemorrhagic fever 4 4 4 3V 3 4 + fever) TBE B Arbovirus) 149 Oncornavirus B Retroviridae/ Oncovirinae 2 Oncornavirus C, 150 Retroviridae/ Oncovirinae 2 except HTLV I and II 151 Orbiviruses Reoviridae 2 2 2 2 human, 3 152 Orf virus Poxviridae/ Parapoxvirus 2 implied 2 2 implied 2 2 + + animal Bunyaviridae/ Bunyavirus 3 arbovirus 153 Oropouche virus 3 arbovirus table 2 implied 3 3 3 + Group table Other bunyaviridae 154 known to be Bunyaviridae 2 implied 2 pathogenic 155 other calciviridae Calciviridae 2 2 2 2 other flaviviruses 156 known to be Flavivirus see LBG 2 pathogenic epidemic 157 other hantaviruses Bunyaviridae/ Hantaviruses 3 3 2 3, implied nephrosis virus other known Togaviridae/ Alphavirus (Grp 158 2 alphaviruses A Arbovirus) other pathogenic 159 orthopoxviruses not Poxviridae/ Orthopoxvirus 3 in RG 2 or 4 160 Ouango, Oubangui X-Arboviruses Papillomaviruses 161 Papovaviridae 2 2 all isolates 2 D(d) 2 + (human) Parainfluenza virus Paramyxoviridae/ 162 2 implied Type 3, SF4 strain Paramyxovirus Paramyxoviridae/ 163 Parainfluenza viruses Types 1 to 4 2 (Types 1-4) 2 implied 2 (Types 1-4) 2 2 (Types 1-4) + + Paramyxovirus 164 Paramushir, Piry X-Arboviruses 3 arbovirus table 3 arbovirus 165 Paravaccinia virus Poxviridae 2 implied 2 2 implied 166 Parvovirus (human) Parvoviridae B19 2 (B19) 2 all isolates 2 (B19) 2 (B19) 2, X + 2 ( all types, 167 Polioviruses Picornoviridae/ Enterovirus 2 V 2 (enterovirus) 2 V 2 2, Types 1-3 + wild and Polyomavirus, BK 2 Polyoma all 168 Papovaviridae 2 D(d) 2 + amd JC viruses isolates Flaviviridae/ Flavivirus (Grp 3 arbovirus 3 human, 2 169 Powassan 3 arbovirus table 3 3 + + B Arbovirus) table animal 170 Prospect Hill virus Bunyaviridae/ Hantaviruses 2 arbovirus table 2 arbovirus 2 2 3, implied +

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Herpesviridae/ 171 Pseudorabies virus 2 3 + Alphaherpesviridae 172 Puumala virus Bunyaviridae/ Hantaviruses 3 arbovirus table 3 arbovirus 2 3 3, implied + Rabbitpox virus 2 human, 3 173 Poxviridae 2 2 2 implied 2 + + (vaccinia variant) animal fixed virus is 2, 3 street, 2 174 Rabies virus Rhabdoviridae/ Lyssavirus 2 V /3 2/3 3 V (**) 3 + + street virus, 3 (fixed) 175 Rat leukemia virus Viral vector/Animal retrovirus 1 176 Razdan X-Arboviruses 3 arbovirus table 3 arbovirus 2 177 Reoviruses Reoviridae 2 2 (Orthoreovirus, Respiratory syncytial Paramyxoviridae/ 178 2 2 implied 2 2 2 + + virus Pneumovirus Rhadinovirus, except 179 H. ateles and H. Herpesviridae/ Rhadinovirus 2 saimiri Rhadinovirus, except 180 Herpesviridae 2 H.ateles,H. saimiri Bovine, Equine, 181 Rhinovirus Picornaviridae/ Rhinoviruses 2 (all types) 2 all isolates 2 2 2 + + Human 2, vaccine strain Rift Valley Fever, 3 (MF12 182 Bunyaviridae/ Phleboviruses MP-12; Grp C 3 Zinga 3 3V 3 3 + + (Zinga virus) vaccine strain,2) Bunyaviridae 183 Rochambeau X-Arboviruses 3 arbovirus table 3 arbovirus Flaviviridae/ Flavivirus (Grp 3 arbovirus 184 Rocio 3 arbovirus table 3 3 + B Arbovirus) table Togaviridae/ Alphavirus (Grp 2 arbovirus 185 Ross River virus 2 arbovirus table 2 2 2 2 + A Arbovirus) table 186 Rotavirus (human) Reoviridae 2f 2 all isolates 2 2 2 + + 187 Rubivirus (Rubella) Togaviridae/ Rubivirus 2 2 2 V 2 2 + Russian spring- Flaviviridae/ Flavivirus (Grp 188 summer encephalitis, 4 4 4 3 V 3 3 + B Arbovirus) TBE 189 Sabia Arenaviruses 4 190 Sagiyama X-Arboviruses 3 arbovirus table 3 arbovirus Salanga, Santa 3 arbovirus 191 X-Arboviruses 3 arbovirus table Rosa, Saumarex table Flaviviridae/ Flavivirus (Grp 192 Sammarez Reef 2 B Arbovirus) 193 Sandfly fever virus Bunyaviridae/ Phleboviruses 2 arbovirus table 2 arbovirus 2 2 2 + 194 Scrapie Unconventional agents 2 3 + Togaviridae/ Alphavirus (Grp most recombinant 3 arbovirus 195 Semliki Forest virus 3 arbovirus table 2 2 2 # 2 + A Arbovirus) activities BL2 table

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HP AP (Canada) Annex VIII Sendai virus (murine Paramyxoviruses/ 196 parainfluenza virus Parainfluenza viruses type 1) 197 Seoul virus Bunyaviridae/ Hantaviruses 3 arbovirus table 3 arbovirus 3 3 3, implied + Sepik, Slovakia, 3 arbovirus 198 X-Arboviruses 3 arbovirus table Spondweni table Shope papilloma Papovavirus/ Animal virus 199 1 2 + virus vector Simian 200 immunodeficiency Retroviridae/ Lentiviridae 2/2+/3 3 3 (**) 3 + virus Simian sarcoma 3 implied by 201 Retroviridae 3 + virus, SSV-1 note Simian virus 40 Papovaviridae/ Animal virus 202 1 2 + (SV40) vector hantavirus 203 sin nombre virus Bunyaviridae/ Hantaviruses pulmonary 3 3, implied + syndrome Togaviridae/ Alphavirus (Grp 2 arbovirus 204 Sindbis virus 2 arbovirus table 2 2 2 + + A Arbovirus) table Flaviviridae/ Flavivirus (Grp 3 arbovirus 3 human, 2 205 St. Louis encephalitis 3 arbovirus table 3 3 3 + + B Arbovirus) table animal Subsclerosing 206 Paramyxoviridae pancencephalitis 2( Tamiami, 207 Tacaribe complex Arenaviruses 2 2 Tacribe,Pinchin 2 4 Tacaribe + de) Tamdy, Telok Forest, 3 arbovirus 208 X-Arboviruses 3 arbovirus table Tiacotalpan, table( 2 (Yabapox is 209 Tanapox Poxviridae see Yabapox 2 2 2 implied Tana and Yaba) Bunyaviridae/ Bunyavirus 2 arbovirus 210 Tensaw virus 2 arbovirus table 2 implied Group table Thetalymphocryptovir Herpesviridae/ Animal virus 211 2 all isolates us vector Flaviviridae/ Flavivirus (Grp 3 TB virus, 4 212 tick borne B Arbovirus) TB enceph Tick-borne Dhori & Thogoto 4 (Dhori and 2 (Dhori- and 213 Orthomyxoviridae 4 2 + orthomyxoviridae,TB (EC) Thogoto) Thogoto) 3 see arbovirus 214 Tocio X-Arboviruses 3 arbovirus table table Togaviridae/ Alphavirus (Grp 3 arbovirus 215 Tonate virus 3 arbovirus table 3 (**) 3 + A Arbovirus) table 216 Toroviridae Toroviridae 2

BL RG RG RG RG RG LCDC-96 Belgium-97 ID Name Viral group Comments BMBL-93 CDC NIH rDNA-97 EU-96 Australia-95 HPAP (Canada) Annex VIII 217 Toscana virus Bunyaviridae/ Phleboviruses 2 arbovirus table 2 arbovirus 2 2 2 + 218 Turlock virus X-Arboviruses 2 arbovirus unassigned 219 herpesviruses HHV Herpesviridae 7, HHV8 220 Vaccinia virus Poxviridae/ Orthopoxvirus 2 V 2 2 implied 2 2 2 + + Variola (major and 221 Poxviridae R Restricted 4 4 V 4 # minor) virus Venezuelan equine Togaviridae/ Alphavirus (Grp 2, vaccine strain, 3, ( 2 for 222 3 3 (2, TC-83) 3 V 3 (wild strain) 3, V + + encephalomyelitis A Arbovirus) TC-83 vaccine TC-83) Lab Vesicular stomatitis adapted:Indiana, 3, 2, lab 2 human, 3 223 Rhabdoviridae 3 (exotic, Piry) 2 ( Piry,3) 2 + + virus San Juan, adapted strains animal Glascow, Alagoas Flaviviridae/ Flavivirus (Grp 3 arbovirus 224 Wesselsbron virus 3 arbovirus table 3 (**) 3 + + B Arbovirus) table Flaviviridae/ Flavivirus (Grp 3 arbovirus 225West Nile fever virus 3 arbovirus table 3 3 2 + + B Arbovirus) table Western equine Togaviridae/ Alphavirus (Grp 226 2 ,V 2,V 3 3 V 3 3 + + encephalomyelitis A Arbovirus) 227 Whitepox (Variola) Poxviridae R Restricted 4 4 # + Yabapox virus (Tana 228 Poxviridae 2 2 2 implied 2 2 + + and Yaba) yellow fever virus Flaviviridae/ Flavivirus (Grp 3, see wild type 229 2 2 2 2 + (vaccine strain 17D) B Arbovirus) strain yellow fever virus, Flaviviridae/ Flavivirus (Grp 2, see vaccine 230 3 3 3 3 V 3 # 3 + wild type B Arbovirus) strain, 17D Zinga (See Rift see Rift Valley 231 Bunyaviridae/ Phleboviruses Valley Fever) Fever

(**) - Member States are to ensure that all viruses which have already been isolated in humans and which have not been assessed and allocated in this Annex are classified in Group 2 as a minimum, except where Member States have proof that they are unlikely to cause disease in humans (EU). Please forward any comments or (b) - Hepatitis D virus is pathogenic in workers only in the pesence of simultaneous or secondary infection caused by hepatitis B virus. corrections to Stefan Wagener at: Vaccination against hepatitis B virus will therefore protect workers who are not affected by hepatitis B virus against hepatitis D virus (Delta). [email protected] (d) - Recommended for work involving direct contact with these agents or fax to: (517) 353-4871 V - Vaccine available D - List of workers exposed to this biological agent to be kept for more than 10 years after the end of last known exposure (EU). BL - Biosafety Level AP - Animal Pathogen HP - Human Pathogen