Chapter 1: the Human Organism 1 Chapter 1 Outline 1.1 Anatomy and Physiology 1.2 Structural and Functional Organization of the Human Body A
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Intelligent Design, Abiogenesis, and Learning from History: Dennis R
Author Exchange Intelligent Design, Abiogenesis, and Learning from History: Dennis R. Venema A Reply to Meyer Dennis R. Venema Weizsäcker’s book The World View of Physics is still keeping me very busy. It has again brought home to me quite clearly how wrong it is to use God as a stop-gap for the incompleteness of our knowledge. If in fact the frontiers of knowledge are being pushed back (and that is bound to be the case), then God is being pushed back with them, and is therefore continually in retreat. We are to find God in what we know, not in what we don’t know; God wants us to realize his presence, not in unsolved problems but in those that are solved. Dietrich Bonhoeffer1 am thankful for this opportunity to nature, is the result of intelligence. More- reply to Stephen Meyer’s criticisms over, this assertion is proffered as the I 2 of my review of his book Signature logical basis for inferring design for the in the Cell (hereafter Signature). Meyer’s origin of biological information: if infor- critiques of my review fall into two gen- mation only ever arises from intelli- eral categories. First, he claims I mistook gence, then the mere presence of Signature for an argument against bio- information demonstrates design. A few logical evolution, rendering several of examples from Signature make the point my arguments superfluous. Secondly, easily: Meyer asserts that I have failed to refute … historical scientists can show that his thesis by not providing a “causally a presently acting cause must have adequate alternative explanation” for the been present in the past because the origin of life in that the few relevant cri- proposed candidate is the only known tiques I do provide are “deeply flawed.” cause of the effect in question. -
The Hidden Kingdom
INTRODUCTION Fungi—The Hidden Kingdom OBJECTIVE • To provide students with basic knowledge about fungi Activity 0.1 BACKGROUND INFORMATION The following text provides an introduction to the fungi. It is written with the intention of sparking curiosity about this GRADES fascinating biological kingdom. 4-6 with a K-3 adaptation TEACHER INSTRUCTIONS TYPE OF ACTIVITY 1. With your class, brainstorm everything you know about fungi. Teacher read/comprehension 2. For younger students, hand out the question sheet before you begin the teacher read and have them follow along and MATERIALS answer the questions as you read. • copies of page 11 3. For older students, inform them that they will be given a • pencils brainteaser quiz (that is not for evaluation) after you finish reading the text. VOCABULARY 4. The class can work on the questions with partners or in groups bioremediation and then go over the answers as a class. Discuss any chitin particularly interesting facts and encourage further fungi independent research. habitat hyphae K-3 ADAPTATION kingdom 1. To introduce younger students to fungi, you can make a KWL lichens chart either as a class or individually. A KWL chart is divided moulds into three parts. The first tells what a student KNOWS (K) mushrooms about a subject before it is studied in class. The second part mycelium tells what the student WANTS (W) to know about that subject. mycorrhizas The third part tells what the child LEARNED (L) after studying nematodes that subject. parasitic fungi 2. Share some of the fascinating fungal facts presented in the photosynthesis “Fungi—The Hidden Kingdom” text with your students. -
Framing Major Prebiotic Transitions As Stages of Protocell Development: Three Challenges for Origins-Of-Life Research
Framing major prebiotic transitions as stages of protocell development: three challenges for origins-of-life research Ben Shirt-Ediss1, Sara Murillo-Sánchez2,3 and Kepa Ruiz-Mirazo*2,3 Commentary Open Access Address: Beilstein J. Org. Chem. 2017, 13, 1388–1395. 1Interdisciplinary Computing and Complex BioSystems Group, doi:10.3762/bjoc.13.135 University of Newcastle, UK, 2Dept. Logic and Philosophy of Science, University of the Basque Country, Spain and 3Biofisika Institute Received: 16 February 2017 (CSIC, UPV-EHU), Spain Accepted: 27 June 2017 Published: 13 July 2017 Email: Kepa Ruiz-Mirazo* - [email protected] This article is part of the Thematic Series "From prebiotic chemistry to molecular evolution". * Corresponding author Guest Editor: L. Cronin Keywords: functional integration; origins of life; prebiotic evolution; protocells © 2017 Shirt-Ediss et al.; licensee Beilstein-Institut. License and terms: see end of document. Abstract Conceiving the process of biogenesis as the evolutionary development of highly dynamic and integrated protocell populations provides the most appropriate framework to address the difficult problem of how prebiotic chemistry bridged the gap to full-fledged living organisms on the early Earth. In this contribution we briefly discuss the implications of taking dynamic, functionally inte- grated protocell systems (rather than complex reaction networks in bulk solution, sets of artificially evolvable replicating molecules, or even these same replicating molecules encapsulated in passive compartments) -
BIOSC 0805: the HUMAN BODY Department of Biological Sciences University of Pittsburgh
Syllabus: Biosc 0805, The Human Body BIOSC 0805: THE HUMAN BODY Department of Biological Sciences University of Pittsburgh Faculty Zuzana Swigonova, Ph.D. Office: 356 Langley Hall (Third floor, the bridge between Clapp and Langley halls) tel.: 412-624-3288; email: [email protected] Office hours Office hours: Mondays 10:00 – 11:30 AM, 356 Langley Hall Wednesdays 1:00 – 2:30 PM, 356 Langley Hall Office hours by appointment can be arranged by email. Lecture Time Tuesdays & Thursdays, 2:30 – 3:45 PM, 169 Crawford Hall Course objectives This is a course in human biology and physiology for students not majoring in biology. The goal is to provide students with an understanding of fundamental principles of life with an emphasis on the human body. We will start by covering basic biochemistry and cell biology and then move on to the structure and function of human organ systems. An essential part of the course is a discussion of health issues of general interest, such as infectious, autoimmune and neurodegenerative diseases; asthma and allergy; nutrition and health; stem cells research and cloning; and methods of contraception and reproductive technologies. Textbook • Biology. A guide to the natural world, by David Krogh. Pearson, Benjamin Cummings Publishing Company. (ISBN#:0-558-65495-9). This is custom made textbook that includes only the parts of the original edition that are covered in the course. It is available in the Pitt bookstore. • You can also use the full 4th or 3rd edition, however, be aware that the chapters in earlier editions are rearranged in a different order and may be lacking some parts included in the later edition. -
Chapter 32 FOREIGN BODIES of the HEAD, NECK, and SKULL BASE
Foreign Bodies of the Head, Neck, and Skull Base Chapter 32 FOREIGN BODIES OF THE HEAD, NECK, AND SKULL BASE RICHARD J. BARNETT, MD* INTRODUCTION PENETRATING NECK TRAUMA Anatomy Emergency Management Clinical Examination Investigations OPERATIVE VERSUS NONOPERATIVE MANAGEMENT Factors in the Deployed Setting Operative Management Postoperative Care PEDIATRIC INJURIES ORBITAL FOREIGN BODIES SUMMARY CASE PRESENTATIONS Case Study 32-1 Case Study 32-2 Case Study 32-3 Case Study 32-4 Case Study 32-5 Case Study 32-6 *Lieutenant Colonel, Medical Corps, US Air Force; Chief of Facial Plastic Surgery/Otolaryngology, Eglin Air Force Base Department of ENT, 307 Boatner Road, Suite 114, Eglin Air Force Base, Florida 32542-9998 423 Otolaryngology/Head and Neck Combat Casualty Care INTRODUCTION The mechanism and extent of war injuries are sig- other military conflicts. In a study done in Croatia with nificantly different from civilian trauma. Many of the 117 patients who sustained penetrating neck injuries, wounds encountered are unique and not experienced about a quarter of the wounds were from gunshots even at Role 1 trauma centers throughout the United while the rest were from shell or bomb shrapnel.1 The States. Deployed head and neck surgeons must be injury patterns resulting from these mechanisms can skilled at performing an array of evaluations and op- vary widely, and treating each injury requires thought- erations that in many cases they have not performed in ful planning to achieve a successful outcome. a prior setting. During a 6-month tour in Afghanistan, This chapter will address penetrating neck injuries all subspecialties of otolaryngology were encountered: in general, followed specifically by foreign body inju- head and neck (15%), facial plastic/reconstructive ries of the head, face, neck, and skull base. -
1 Introduction to Cell Biology
1 Introduction to cell biology 1.1 Motivation Why is the understanding of cell mechancis important? cells need to move and interact with their environment ◦ cells have components that are highly dependent on mechanics, e.g., structural proteins ◦ cells need to reproduce / divide ◦ to improve the control/function of cells ◦ to improve cell growth/cell production ◦ medical appli- cations ◦ mechanical signals regulate cell metabolism ◦ treatment of certain diseases needs understanding of cell mechanics ◦ cells live in a mechanical environment ◦ it determines the mechanics of organisms that consist of cells ◦ directly applicable to single cell analysis research ◦ to understand how mechanical loading affects cells, e.g. stem cell differentation, cell morphology ◦ to understand how mechanically gated ion channels work ◦ an understanding of the loading in cells could aid in developing struc- tures to grow cells or organization of cells more efficiently ◦ can help us to understand macrostructured behavior better ◦ can help us to build machines/sensors similar to cells ◦ can help us understand the biology of the cell ◦ cell growth is affected by stress and mechanical properties of the substrate the cells are in ◦ understanding mechan- ics is important for knowing how cells move and for figuring out how to change cell motion ◦ when building/engineering tissues, the tissue must have the necessary me- chanical properties ◦ understand how cells is affected by and affects its environment ◦ understand how mechanical factors alter cell behavior (gene expression) -
The Concept of Organism, a Historical and Conceptual Critique
Do organisms have an ontological status? Charles T. Wolfe Unit for History and Philosophy of Science University of Sydney [email protected] forthcoming in History and Philosophy of the Life Sciences 32:2-3 (2010) Abstract The category of „organism‟ has an ambiguous status: is it scientific or is it philosophical? Or, if one looks at it from within the relatively recent field or sub-field of philosophy of biology, is it a central, or at least legitimate category therein, or should it be dispensed with? In any case, it has long served as a kind of scientific “bolstering” for a philosophical train of argument which seeks to refute the “mechanistic” or “reductionist” trend, which has been perceived as dominant since the 17th century, whether in the case of Stahlian animism, Leibnizian monadology, the neo-vitalism of Hans Driesch, or, lastly, of the “phenomenology of organic life” in the 20th century, with authors such as Kurt Goldstein, Maurice Merleau-Ponty, and Georges Canguilhem. In this paper I try to reconstruct some of the main interpretive „stages‟ or „layers‟ of the concept of organism in order to critically evaluate it. How might „organism‟ be a useful concept if one rules out the excesses of „organismic‟ biology and metaphysics? Varieties of instrumentalism and what I call the „projective‟ concept of organism are appealing, but perhaps ultimately unsatisfying. 1. What is an organism? There have been a variety of answers to this question, not just in the sense of different definitions (an organism is a biological individual; it is a living being, or at least the difference between a living organism and a dead organism is somehow significant in a way that does not seem to make sense for other sorts of entities, like lamps and chairs; it is a self-organizing, metabolic system; etc.) but more tendentiously, in the 1 sense that philosophers, scientists, „natural philosophers‟ and others have both asserted and denied the existence of organisms. -
Human Anatomy and Physiology
LECTURE NOTES For Nursing Students Human Anatomy and Physiology Nega Assefa Alemaya University Yosief Tsige Jimma University In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education 2003 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2003 by Nega Assefa and Yosief Tsige All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty in a health care field. Human Anatomy and Physiology Preface There is a shortage in Ethiopia of teaching / learning material in the area of anatomy and physicalogy for nurses. The Carter Center EPHTI appreciating the problem and promoted the development of this lecture note that could help both the teachers and students. -
Bacteria – Friend Or Foe?
Bacteria – Friend or Foe? By Rachel L. Dittmar & Rosa M. Santana Carrero [email protected], [email protected] April 2020 Danger! Sick! Gross! Vaccine! Disease! Medicine! Dirty! MRSA! Eww! E. coli! What is the first thing that comes to mind when you hear “bacteria”? Science! Microscope! MRSA! Salmonella! Hospital! Germs! Staph! Food! Small! 2 Introduction to Bacteria 3 Bacterial nomenclature • Bacteria are referred to by their genus and species, with genus coming first and species coming last: Escherichia coli Escherichia: genus Species: coli Bacteria names are ALWAYS italicized. Genus names are capitalized and species names are not. Sometimes, the genus is abbreviated by its first initial: E. coli 4 Bacteria are prokaryotes. 5 What are prokaryotes? • Plasma membrane separates the cell from its surrounding environment • Cytoplasm contains organelles • Contain DNA consisting of a single large, circular chromosome • Ribosomes make proteins 6 Prokaryotes v. Eukaryotes 7 Image from: https://www.difference.wiki/prokaryotic-cell-vs-eukaryotic-cell/ How do these organisms differ? Prokaryotes Eukaryotes - circular DNA - linear DNA (found in nucleus) - no nucleus - nucleus - no membrane bound organelles - membrane bound organelles - small- less than 10μm - larger than 10μm - unicellular - can be unicellular and multicellular 8 Bacteria are very small. 9 How big are bacteria? Bacteria are very small: 0.1 – 5.0 micrometers. A micrometer (μm) is 0.000001 meters or 0.001 millimeters (mm) For comparison, a human hair is 30 – 100 μm Image from: https://www.khanacademy.org/science/high-school-biology/hs-cells/hs-prokaryotes-and-eukaryotes/a/prokaryotic-cells 10 Bacteria are classified by phenotype or genotype. -
The Human Body Is Like a Complex Machine, with Many Little Parts That Work by Themselves Or with Other Parts to Perform Specific Functions
Have you ever wondered about how the human body works? The human body is like a complex machine, with many little parts that work by themselves or with other parts to perform specific functions. Sometimes, it seems like our body has a mind of its own and it embarrasses you. Have you ever passed gas accidentally when other people were around? In most cases, the things that your body does are normal, but it’s important to know your body so you can recognize what is normal body behavior and what is not. If there is a problem with how your body works, by recognizing that there is a problem, you can take steps to fix it or get help. To understand how the body works, it helps to understand how the body is organized. The smallest living unit in any organism is a cell and the human body is made up of trillions of them. That is more than 1,000,000,000,000 cells! Cells are so small you cannot see them without a microscope. Cells are important for many reasons. They produce the energy in your body to do daily activities, or hold the coded instructions for everything from the color of your hair to whether you have freckles or not. Cells differentiate from each other to perform different, important tasks within the body. For example, some cells might become brain cells while others make bone, and red blood cells carry oxygen throughout the body, while white blood cells fight infection. When a group of cells work together to perform ?a specific function, they are called tissue. -
Single-Celled Organisms
Single-Celled Organisms • Humans are made up of millions of tiny cells (multi-celled organisms). • Microorganisms are made up of only ONE cell (single-celled organisms) 1.Single-celled organisms are simple life forms Include: bacteria, protists and others. They move, find food, grow, and make new organisms. 2. Bacteria are one-celled organisms that do NOT have a nucleus. The material that is usually in a nucleus can be found all over the cytoplasm instead. More bacteria on earth than any other living thing Some bacteria are helpful, and some are harmful. One handful of soil can contain billions of bacteria. 3. Protists are a kind of single-celled organism. They live everywhere including pond water, saltwater, animals, and humans Amoebas have a cell membrane, cytoplasm, and a nucleus They move by: changing their shape. 4. Algae are plant-like organisms that Live in water, moist places, and under rocks Among the oldest things on earth! Algae have a cell membrane, cytoplasm, nucleus, and chloroplast. Algae produce most of the oxygen that you breathe! 5. How do single-celled organisms move? Tail-like parts called flagella Hair like structures called cilia Paramecium also use their cilia to get food Multi-Celled Organisms Multi-celled organism is made of up of more than one cell. Plants, animals and other living things. Made up of different kinds of cells that have certain jobs to do. Muscle cells, white blood cells, and nerve cells For example: the cells that make up your heart work together to move oxygen and blood to other cells throughout your body. -
Biology 197: Principles of Organismal Biology Section B: T, R 9:30–10:45 AM Section D: T, R 1:30–2:45 PM Spring 2011 Birck Hall 003 Instructor: Dr
Biology 197: Principles of Organismal Biology Section B: T, R 9:30–10:45 AM Section D: T, R 1:30–2:45 PM Spring 2011 Birck Hall 003 Instructor: Dr. Phil Novack‐Gottshall Office: Birck 332 E‐mail: Blackboard mail preferred Office hours: T 11–1:30, W 11–1, R 11–12:30 (or pnovack‐[email protected]) or by appointment Course Description Organismal biology is one of the major branches of biology and is concerned with all aspects of the life of organisms, including their biodiversity, anatomical structure, physiology, development, biogeography, and ecology. This course is an introductory course required for all biological sciences majors, but it is also useful for gaining basic biological literacy and for those pursuing careers in human and veterinary medicine, psychiatry, agriculture, forestry, microbiology, conservation, ecology, paleontology, environmental science, law, political science, and even cooking, cheese making, and brewing of alcohol. In this class, we will learn the major groups of animals, fungi, plants, protists, algae, and bacteria; their basic characteristics; and how biologists study these organisms to understand their rich evolutionary history, ecological interactions, amazing adaptations, and relevance to humans and other species. In particular, you will practice learning how to view the world and to think like an organismal biologist. Learning objectives 1) Explain the scientific method of organismal biologists to understand the natural world. 2) Identify the major lineages of life through study of their biodiversity, anatomy, physiology, development, behavior, biogeography, fossil record, and ecology. 3) Explain the significance of major transitions in organismal evolution: photosynthesis, endosymbiosis, sexual reproduction, multicellularity, skeletonization, cephalization, terrestrialization, mobility, and carnivory, among others.