United States Patent Office Patented Jan

Total Page:16

File Type:pdf, Size:1020Kb

United States Patent Office Patented Jan 2,698,819 United States Patent Office Patented Jan. 4, 1955, 2. ment at the beginning of the paragraph. It will be un 2,698,819 derstood that the compounds, by behavior and upon analysis, demonstrate the presence of the quadrivalent ETHYLENEDIAMENE TETRAACETIC ACID PERI. acid radical (C10H12OgNal, and of three iodine atoms, ODDES AND COMPOSITIONS THEREOF: together with the existence of four monovalent bonds satisfied in total or in part by hydrogen and for the rest Leo W. Ziemak, Pittsburgh, Pa., assignor to Chilean by, an alkali metal substituent, or satisfied by one bivalent: Nitrate Sales. Corporation, New York, N.Y., a corpo alkaline earth element with the remaining two mono ration of New York valencies supplied by hydrogen or an alkali metal sub stituent. In this connection, it is to..be remembered that Norawing. Application June 26, 1951, O ultimate analyses of compositions, for determining a Serial No. 233,711 molecular formula of 700 or higher mass or weight units, 8. Caints. C. 167-7) : have uncertainty as to the number of hydrogens present: and that the foregoing is stated as a type formula, rather. This invention relates to new chemical compounds hav than as meaning that the number of hydrogens present, s -ing properties adapting them to bactericidal uses, and to 5 for example in the hydrogen periodide compound of bactericidal compositions-including the same. ethylenediamine tetra-acetic acid, is sixteen or seven For the sterilization of water it is desirable to have a tee. composition which can be prepared in a dry, stable tablet This general empiric formula for the compound also, or pill form which upon dissolution in water will re includes complexes in which the basic component is one lease iodine, and sterilize the water without giving - a 20 of the compounds of said formula, and the complex sub strong offensive taste thereto by reason of end products, stance is one of molecular association in which there is and make the water available for safe drinking or for bound to a stated compound containing ammonium as a laving wounded areas. Likewise, it is desirable to have substituent, an excess of periodide such as ammonium a dusting powder which is stable and non-hygroscopic, iodide-iodine. and which can be employed directly upon wounds. 25, EXAMPLE I Proposals have been made to prepare iodine-releasing compositions, in which the iodine is not originally free Dipotassium salt of ethylenediamine tetra-acetic acid but separates when the composition is brought into con potassium triodide. tact with water, either in preparing a sterilizing or sterilized 13.8 grams of U. S. P. potassium carbonate was dis-- liquid, or when used as a dusting powder. Many such 30. solved in 20 cc. of water, and to this was slowly added proposals recommend the use of aromatic or other cyclic 14.6 grams of ethylenediamine tetra-acetic acid. The compounds; such as iodized aromatic chloramine, which mixture was heated gently until a homogeneous solution upon releasing iodine has a high odor of chlorinated wa was obtained. A second solution was prepared by dis ter and phenol: or such as morpholine periodide. A Solving 8.3 grams of U.S. P. potassium iodide in 20 cc. difficulty in such preparations is that the composition of water; and 14 grams of U.S. P. iodine. The sec should be stable in moist air, yet capable of reacting quick ond solution was slowly added, with stirring, to the first ly with water to release the iodine: these are contradic and the resulting solution heated to about 75 C. Upon. tory, and some prior materials have exhibited stability in cooling, a dark crystalline mass settled out almost im air but at the expense of timely and effective release of mediately. The reaction mixture was allowed to stand the iodine upon contact with water or serum, and oth 4. for several hours in an ice bath. The crystals were then ers have effective release at the expense of storage stability rapidly washed first with cold dilute aqueous potassium wherewith some compositions are even deliquescent. iodide, then with cold distilled water, and finally with 95 Furthermore, the end products must not themselves be percent ethyl alcohol. The product was then dried over. toxic or caustic even with accidentally acquired high phosphorus pentoxide; yield 23.5 grams. dosages: and by great preference they should form only 45 The product is crystalline and exhibits, great, stability water-soluble compounds with alkaline earths. Such as in the atmosphere. The vapor tension is very low and . naturally present calcium salts. the odor of iodine is not discernible. When ground to It has long been known that greater quantities of iodine a fine powder, it has a dark red-brown color. It has a can be held in solution in an iodide solution than in wa solubility of 98.8 grams per liter, as measured by the ter alone: apparently by reason of existence of Such com quantity of iodine released when a saturated solution is plexes as Ki-2, so-called potassium periodide KI3. formed. The aqueous solution is very similar to that of However, such complexes are unstable. iodine in aqueous potassium iodide. Upon analyses, the It has now been found that a water-soluble, atmos empiric formula closely corresponds to C10H14OaN2K3I3 pherically-stable compound of high available iodine con or C10H13O8N2K3 is, it being remarked that one hydrogen tent, and of crystalline nature, can be prepared by react atom has a weight or mass of one unit in a molecule of ing an alkylamine polycarboxylic acid, namely ethylene about 788 weight or mass units. The theoretical per diamine tetra-acetic acid with an alkali periodide, alkaline centage of iodine in a compound of the empiric formula earth periodide, or hydrogen periodide, that is, with C10H14OsN2K33 is 48.3%; and, assuming that two iodine the double salt or compound of the alkali or alkaline 60 atoms are active, the theoretical percentage of active earth iodide, or hydrogen iodide, with iodine. iodine is 32.2%. The experimental value for active The preferred compound is obtained by treating the iodine determined by titration was 30% : but upon analy tetra-potassium salt of ethylenediamine tetra-acetic acid sis by the Parr bomb method or by the standard U. S. P. with potassium periodide, and separating the molecular method (iodate), the total iodine was noted as 48.8%. complex by crystallization. 6 The compound exhibits great stability to dry heat. A Potassium, sodium, ammonium (which herein is the sample, which had been dried over phosphorus pentoxide, chemical equivalent of an alkali metal element), cal was placed in a drying oven at 100-110° C. for over 24 cium, magnesium, and even hydrogen periodides, or hours; the weight-loss was only 1.2 to 1.3 per cent. The mixtures thereof, may be utilized; and the general em weight-loss occurred within 16 hours of drying; there was piric formula of the compound may be stated as 70 no additional loss of weight even though the drying period CoH12O3N2 MaR3, in which M is a monovalent em was extended to a total of 25 hours. The weight-loss was piric substituent selected from the group consisting of hy apparently due to loss of moisture, for the total iodine drogen, potassium, sodium, and ammonium; and R is content per mole of the triiodide was slightly higher than a divalent empiric substituent selected from the group that found before the test. After the test, the sample could consisting of calcium, magnesium, dihydrogen, hydrogen 75 not be distinguished, by inspection, frcm one which had potassium, hydrogen-sodium, hydrogen-ammonium, that not been so treated. is, compounds of the form Edita (Ca3, Edita The compound is non-hygroscopic in the 2EEGosphere. CaHK23J, Edita Caksa, Edita (H3K23, Edita A sample, which had been dried at 100 to 10 C. for HK313, Edita (H2K2NH431, and the like are includ 16 hours, was exposed to 65 per cent relative humidity at ed, where Edita is an abbreviation for the ethylene 80 70 F. for over 60 hours. The gain in weight was diamine tetraacetic acid radical in the bracketed state only 1.2 per cent, practically the weight lost on drying. 2,698,819 3 4. EXAMPLE 8 showedA second no samplegainin weightwhich inhad the beensame driedperiod over when silica exposed gel to 65 per cent relative humidity at 70 F. Ethylenediamine tetra-acetic acid potassium triodide 66.4 grams of U. S. P. potassium iodide was dissolved EXAMPLE 2 5 in 200 cc. of water, and to this was added 14.6 grams of ethylenediamine tetra-acetic acid. The mixture was heat The disodium salt of ethylenediamine tetra-acetic acid ed until a homogeneous solution was obtained; and then sodium triiodide was prepared as in Example 1, employ 50.8 grams of powdered U. S. P. iodine was slowly added, ing 10.6 grams of U. S. P. sodium carbonate and 7.5 with stirring. The reaction mixture was heated on a grams of U. S. P. sodium iodide in lieu of the potassium 10 steam bath until all the iodine had dissolved. Upon cool salts; yield 32 grams. The product has essentially iden ing the reaction mixture, a dark crystalline mass began tical behavior and stability with that of Example 1; and to settle out almost immediately. The mixture was al its formula upon analysis is in agreement with lowed to stand for several hours in an ice bath. The crystals were separated by filtration, and washed rapidly 5 first with cold dilute aqueous potassium iodide, then EXAMPLE 3 with cold distilled water, and finally with 95 per cent The corresponding disodium salt of ethylenediamine ethyl alcohol.
Recommended publications
  • 10102-68-8 SDS Document Number: 000041 1.2: Recommended Uses and Restrictions Recommended Uses Manufacture of Substances Restrictions Not for Food Or Drug Use
    Safety Data Sheet 1: Identification 1.1: Product Identifier Product Name: CaI2 Product Number(s): 1CAI2-0019F CAS Number: 10102-68-8 SDS Document Number: 000041 1.2: Recommended Uses and Restrictions Recommended Uses Manufacture of substances Restrictions Not for food or drug use. 1.3: Supplier Contact Information APL Engineered Materials, Inc. 2401 N. Willow Rd. Urbana, IL 61802 Phone: 217-367-1340 Fax: 217-367-9084 1.4: Emergency Phone Number United States: 800-255-3924 International: +01-813-248-0585 2: Hazards Identification 2.1: Classifications Not a hazardous substance or mixture - . 2.2: GHS Label Elements Pictograms Signal Word: Hazard Statements Not a hazardous substance. Precautionary Statements Not a hazardous substance. 2.3: Hazards Not Otherwise Classified or Not Covered by GHS Thursday, July 16, 2015 Page 1 of 9 None. 2.4: Amount(s) of substances with unknown toxicity None 3: Composition/Information on Ingredients 3.1: .Ingredient .Weight% .Formula .CAS Number .Mol Wt .EC Number CaI2 100 CaI2 10102-68-8 293.89 233-276-8 3.2: Other Hazardous components none 3.3: Trade Secret Disclaimer none 3.4: Synonyms Calcium Iodide 4: First Aid Measures 4.1: First Aid General Remove person from area of exposure and remove any contaminated clothing Consult with physician and provide this Safety Data Sheet In contact with eyes Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Seek medical attention if irritation develops or persists In contact with skin Wash thoroughly with soap and plenty of water.
    [Show full text]
  • IODINE Its Properties and Technical Applications
    IODINE Its Properties and Technical Applications CHILEAN IODINE EDUCATIONAL BUREAU, INC. 120 Broadway, New York 5, New York IODINE Its Properties and Technical Applications ¡¡iiHiüíiüüiütitittüHiiUitítHiiiittiíU CHILEAN IODINE EDUCATIONAL BUREAU, INC. 120 Broadway, New York 5, New York 1951 Copyright, 1951, by Chilean Iodine Educational Bureau, Inc. Printed in U.S.A. Contents Page Foreword v I—Chemistry of Iodine and Its Compounds 1 A Short History of Iodine 1 The Occurrence and Production of Iodine ....... 3 The Properties of Iodine 4 Solid Iodine 4 Liquid Iodine 5 Iodine Vapor and Gas 6 Chemical Properties 6 Inorganic Compounds of Iodine 8 Compounds of Electropositive Iodine 8 Compounds with Other Halogens 8 The Polyhalides 9 Hydrogen Iodide 1,0 Inorganic Iodides 10 Physical Properties 10 Chemical Properties 12 Complex Iodides .13 The Oxides of Iodine . 14 Iodic Acid and the Iodates 15 Periodic Acid and the Periodates 15 Reactions of Iodine and Its Inorganic Compounds With Organic Compounds 17 Iodine . 17 Iodine Halides 18 Hydrogen Iodide 19 Inorganic Iodides 19 Periodic and Iodic Acids 21 The Organic Iodo Compounds 22 Organic Compounds of Polyvalent Iodine 25 The lodoso Compounds 25 The Iodoxy Compounds 26 The Iodyl Compounds 26 The Iodonium Salts 27 Heterocyclic Iodine Compounds 30 Bibliography 31 II—Applications of Iodine and Its Compounds 35 Iodine in Organic Chemistry 35 Iodine and Its Compounds at Catalysts 35 Exchange Catalysis 35 Halogenation 38 Isomerization 38 Dehydration 39 III Page Acylation 41 Carbón Monoxide (and Nitric Oxide) Additions ... 42 Reactions with Oxygen 42 Homogeneous Pyrolysis 43 Iodine as an Inhibitor 44 Other Applications 44 Iodine and Its Compounds as Process Reagents ...
    [Show full text]
  • The Replacement of Calcium Carbonate with Calcium Chloride and Calcium Fluoride in a Whiteware Body
    Scholars' Mine Bachelors Theses Student Theses and Dissertations 1933 The replacement of calcium carbonate with calcium chloride and calcium fluoride in a whiteware body Charles Richard Rosenbaum Follow this and additional works at: https://scholarsmine.mst.edu/bachelors_theses Part of the Ceramic Materials Commons Department: Materials Science and Engineering Recommended Citation Rosenbaum, Charles Richard, "The replacement of calcium carbonate with calcium chloride and calcium fluoride in a whiteware body" (1933). Bachelors Theses. 58. https://scholarsmine.mst.edu/bachelors_theses/58 This Thesis - Open Access is brought to you for free and open access by Scholars' Mine. It has been accepted for inclusion in Bachelors Theses by an authorized administrator of Scholars' Mine. This work is protected by U. S. Copyright Law. Unauthorized use including reproduction for redistribution requires the permission of the copyright holder. For more information, please contact [email protected]. THE ~PLACEMENT OF CALCIUM CARBO ATE WITH CALCIUM CHLORIDE ~~ . AND CALCIUM FLUORIDE IN A WHITEWARE BODY BY CHARLES RICHARD ROSENBAUM 1\/ A ~HESIS ·submitted _to the faculty of. the SCHOOL OF MINES AND METALLURGY OF THE UNIVERSITY OF MISSOURI in partial-fulfillment rof.the ·work-requlred·for the Degree .. Of BACHELOR- OF.- SCIENCE IN· eERAMIC .. ENGINEERING Rolla, . Mo. 1933. Approved by a222. a<9zmt:d? ~ Professor of Ceramic Eng1neer~ng. '\ THE REPLACE1mNT OF CALCIUM CARBONATE WITH CALCIUM. CHLORIDE AND CALCIUM FLUORIDE IN A WHITEWARE BODY BY CHARLES RICHARD ROSENBAUM IY' A THESI.S submitted to the faculty of the SCHOOL OF MINES AND METALLURGY OF THE UNIVERSITY OF MISSOURI in partial fulfillment of the work required for the Degree Of BACHELOR OF SCIENCE IN CERAMIC ENGINEERING Rolla, Mo.
    [Show full text]
  • Nature [December 22, 1904
    180 NATURE [DECEMBER 22, 1904 As an example of the successful accomplishment this spherical globule when solidified forms the ruby. of a difficult task, we reproduce (Fig. I) the photo­ The cooling has to be very gradual, so that the crystal­ graph of kittiwake gulls nesting on the precipitous line particles have time to become regularly arranged, face of a cliff, approach to which was effected by climb­ or an opaque product is obtained. If the ovoid mass ing down a narrow gulley and then scrambling over is carefully detached when cold, it splits up into two seaweed-clad boulders, to the imminent peril of the nearly equal portions, but not along a cleavage-plane. camera. The product so obtained is !in individual crystal, and As a specimen of really excellent bird-photography, the direction of its principal optic axis is never very we present to our readers the picture of a group of different from that of the major axis of the ovoid. young ringed plovers (Fig. 2), the mottled down of The product when cut cannot be distinguished by which harmonises so admirably at a short distance with its chemical, physical, or optical properties from a their surroundings. stone cut from a natural ruby. The operation may If it be said that this notice is purely commendatory, be considered successful when the clear product weighs and contains nothing in the way of criticism, the reply 12 to IS carats, and has a real diameter of 5 or 6 is that we have found nothing to criticise or to con- millimetres.
    [Show full text]
  • Consideration of Mandatory Fortification with Iodine for Australia and New Zealand Food Technology Report
    CONSIDERATION OF MANDATORY FORTIFICATION WITH IODINE FOR AUSTRALIA AND NEW ZEALAND FOOD TECHNOLOGY REPORT December 2007 1 Introduction Food Standards Australia New Zealand is considering mandatory fortification of the food supply in Australia and New Zealand with iodine. Generally, the addition of iodine to foods is technologically feasible. However, in some instances the addition of iodine can lead to quality changes in food products such as appearance, taste, odour, texture and shelf life. These changes will depend on the chemical form of iodine used as a fortificant, the chemistry of the food that is being fortified, the food processes involved in manufacture and possible processing interactions that could occur during distribution and storage. Many foods have been fortified with iodine and the potassium salts of iodine compounds have been used as the preferred form. 2 Forms of Iodine Iodine is normally introduced, or supplemented, as the iodide or iodate of potassium, calcium or sodium. The following table lists different chemical forms of iodine along with their important physical properties. Table 1: Physical Properties of Iodine and its Compounds Name Chemical Formula % Iodine Solubility in water (g/L) 0°C 20°C 30°C 40°C 60°C Iodine I2 100 - - 0.3 0.4 0.6 Calcium iodide CaI2 86.5 646 676 690 708 740 Calcium iodate Ca(IO3)2.6H2O 65.0 - 1.0 4.2 6.1 13.6 Potassium iodide KI 76.5 1280 1440 1520 1600 1760 Potassium iodate KIO3 59.5 47.3 81.3 117 128 185 Sodium iodide NaI.2H20 85.0 1590 1790 1900 2050 2570 Sodium iodate NaIO3 64.0 - 25.0 90.0 150 210 Adapted from Mannar and Dunn (1995) 2.1 Potassium Iodide Potassium iodide (KI) is highly soluble in water.
    [Show full text]
  • Chemical Substances Exempt from Notification of Manufacturing/Import Amount
    Chemical Substances Exempt from Notification of Manufacturing/Import Amount A list under Chemical Substance Control Law (Japan) 2014-3-24 Official issuance: Joint Notice No.1 of MHLW, METI and MOE English source: Chemical Risk Information Platform (CHRIP) Edited by: https://ChemLinked.com ChemLinked Team, REACH24H Consulting Group| http://chemlinked.com 6 Floor, Building 2, Hesheng Trade Centre, No.327 Tianmu Mountain Road, Hangzhou, China. PC: 310023 Tel: +86 571 8700 7545 Fax: +86 571 8700 7566 Email: [email protected] 1 / 1 Specification: In Japan, all existing chemical substances and notified substances are given register numbers by Ministry of International Trade and Industry (MITI Number) as a chemical identifier. The Japanese Chemical Management Center continuously works on confirming the mapping relationships between MITI Numbers and CAS Registry Numbers. Please enter CHRIP to find if there are corresponding CAS Numbers by searching the substances’ names or MITI Numbers. The first digit of a MITI number is a category code. Those adopted in this List are as follows: 1: Inorganic compounds 2: Chained organic low-molecular-weight compounds 3: Mono-carbocyclic organic low-molecular-weight compounds 5: Heterocyclic organic low-molecular-weight compounds 6: Organic compounds of addition polymerization 7: Organic compounds of condensation polymerization 8: Organic compounds of modified starch, and processed fats and oils 9: Compounds of pharmaceutical active ingredients, etc. This document is provided by ChemLinked, a division of REACH24H Consulting Group. ChemLinked is a unique portal to must-know EHS issues in China, and essential regulatory database to keep all EHS & Regulatory Affairs managers well-equipped. You may subscribe and download this document from ChemLinked.com.
    [Show full text]
  • THE INTERCHANGEABILITY of the ELEMENTS CHLORINE and IODINE in CULTURE MEDIA for HUMAN THYROID FIBROBLASTS Among Those Elements W
    THE INTERCHANGEABILITY OF THE ELEMENTS CHLORINE AND IODINE IN CULTURE MEDIA FOR HUMAN THYROID FIBROBLASTS JOHANNES P. M. VOGELAAR, D.M.S., AND ELEANOR ERLICHMAN, B.S. (From the Institute of Cancer Research, Columbia University, and St. Luke's Hospital, New York City') Among those elements which occur only .in minor amounts in the human body, none has such an interesting history or has been the subject of so much research as iodine. Although there can be no doubt concerning its physiologi- cal significance, actually very little is known about the requirement of various cells and tissues for this element in both its organic and inorganic forms. In view of the fact that the human body not only contains chlorine and iodine, but also fluorine and bromine, the question naturally arises whether all are vital elements and to what extent they can replace one another. The experi- ments reported in this article were undertaken to determine the interchange- ability of chlorine and iodine in culture media for human thyroid fibroblasts. The effect of iodine and iodides on tissue cultures has been studied by various investigators. Pitini ( 12) observed a stimulating effect of potassium iodide on the growth of spleen and sciatic nerve of young guinea-pigs. Glass capillaries filled with a 10 per cent solution of the iodide were placed in close proximity to the cultures. In the interpretation of the results obtained with such a method it must be borne in mind that divers uncontrollable factors may affect the tissue growth, such as local changes in the osmotic pressure and in the pH of the culture medium.
    [Show full text]
  • Chemical Resistance 100% SOLIDS EPOXY SYSTEMS
    Chemical Resistance 100% SOLIDS EPOXY SYSTEMS CHEMICAL 8300 SYSTEM 8200 SYSTEM 8000 SYSTEM OVERKOTE PLUS HD OVERKOTE HD OVERKRETE HD BASED ON ONE YEAR IMMERSION TESTING –––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––––– Acetic Acid (0-15%) G II Acetonitrile LLG L Continuous Immersion Acetone (0-20%) LLL Acetone (20-30%) Suitable for continuous immersion in that chemical (based on LLG Acetone (30-50%) L G I ONE YEAR testing) to assure unlimited service life. Acetone (50-100%) G II Acrylamide (0-50%) LLL G Short-Term Exposure Adipic Acid Solution LLL Alcohol, Isopropyl LLL Suitable for short-term exposure to that chemical such as Alcohol, Ethyl LLG secondary containment (72 hours) or splash and spill Alcohol, Methyl LLI (immediate clean-up). Allyl Chloride LLI Allylamine (0-20%) L L I Allylamine (20-30%) L G I I Not Suitable Allylamine (30-50%) GGI Not suitable for any exposure to that chemical. Aluminum Bromide LL– Aluminum Chloride L L – Aluminum Fluoride (0-25%) L L – This chart shows chemical resistance of our various Aluminum Hydroxide LLL 1 topping materials (90 mils – ⁄4"). These ratings are based on Aluminum Iodide LL– temperatures being ambient. At higher temperatures, chemical Aluminum Nitrate LL– resistance may be effected. When chemical exposure is Aluminum Sodium Chloride L L – minimal to non-existent, a 9000 System–FlorClad™ HD or Aluminum Sulfate LLL 4600 System– BriteCast™ HD may be used. Alums L L L 2-Aminoethoxyethanol Resistance data is listed with the assumption that the material GGG has properly cured for at least four days, at recommended Ammonia – Wet L L – temperatures, prior to any chemical exposure.
    [Show full text]
  • High Purity Inorganics
    High Purity Inorganics www.alfa.com INCLUDING: • Puratronic® High Purity Inorganics • Ultra Dry Anhydrous Materials • REacton® Rare Earth Products www.alfa.com Where Science Meets Service High Purity Inorganics from Alfa Aesar Known worldwide as a leading manufacturer of high purity inorganic compounds, Alfa Aesar produces thousands of distinct materials to exacting standards for research, development and production applications. Custom production and packaging services are part of our regular offering. Our brands are recognized for purity and quality and are backed up by technical and sales teams dedicated to providing the best service. This catalog contains only a selection of our wide range of high purity inorganic materials. Many more products from our full range of over 46,000 items are available in our main catalog or online at www.alfa.com. APPLICATION FOR INORGANICS High Purity Products for Crystal Growth Typically, materials are manufactured to 99.995+% purity levels (metals basis). All materials are manufactured to have suitably low chloride, nitrate, sulfate and water content. Products include: • Lutetium(III) oxide • Niobium(V) oxide • Potassium carbonate • Sodium fluoride • Thulium(III) oxide • Tungsten(VI) oxide About Us GLOBAL INVENTORY The majority of our high purity inorganic compounds and related products are available in research and development quantities from stock. We also supply most products from stock in semi-bulk or bulk quantities. Many are in regular production and are available in bulk for next day shipment. Our experience in manufacturing, sourcing and handling a wide range of products enables us to respond quickly and efficiently to your needs. CUSTOM SYNTHESIS We offer flexible custom manufacturing services with the assurance of quality and confidentiality.
    [Show full text]
  • Calcium Iodide
    Calcium iodide sc-257211 Material Safety Data Sheet Hazard Alert Code EXTREME HIGH MODERATE LOW Key: Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Calcium iodide STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. NFPA FLAMMABILITY0 HEALTH2 HAZARD INSTABILITY0 SUPPLIER Santa Cruz Biotechnology, Inc. 2145 Delaware Avenue Santa Cruz, California 95060 800.457.3801 or 831.457.3800 EMERGENCY ChemWatch Within the US & Canada: 877-715-9305 Outside the US & Canada: +800 2436 2255 (1-800-CHEMCALL) or call +613 9573 3112 SYNONYMS Ca-I2, CaI2.6H2O, "calcium diiodide hexahydrate" Section 2 - HAZARDS IDENTIFICATION CHEMWATCH HAZARD RATINGS Min Max Flammability 0 Toxicity 0 Min/Nil=0 Body Contact 2 Low=1 Reactivity 0 Moderate=2 High=3 Chronic 2 Extreme=4 CANADIAN WHMIS SYMBOLS 1 of 9 EMERGENCY OVERVIEW RISK Irritating to eyes and skin. POTENTIAL HEALTH EFFECTS ACUTE HEALTH EFFECTS SWALLOWED ! The material has NOT been classified by EC Directives or other classification systems as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. EYE ! This material can cause eye irritation and damage in some persons. SKIN ! This material can cause inflammation of the skin oncontact in some persons. ! The material may accentuate any pre-existing dermatitis condition. ! Skin contact is not thought to have harmful health effects (as classified under EC Directives); the material may still produce health damage following entry through wounds, lesions or abrasions. ! Open cuts, abraded or irritated skin should not be exposed to this material. ! Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects.
    [Show full text]
  • Chemical Names and CAS Numbers Final
    Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number C3H8O 1‐propanol C4H7BrO2 2‐bromobutyric acid 80‐58‐0 GeH3COOH 2‐germaacetic acid C4H10 2‐methylpropane 75‐28‐5 C3H8O 2‐propanol 67‐63‐0 C6H10O3 4‐acetylbutyric acid 448671 C4H7BrO2 4‐bromobutyric acid 2623‐87‐2 CH3CHO acetaldehyde CH3CONH2 acetamide C8H9NO2 acetaminophen 103‐90‐2 − C2H3O2 acetate ion − CH3COO acetate ion C2H4O2 acetic acid 64‐19‐7 CH3COOH acetic acid (CH3)2CO acetone CH3COCl acetyl chloride C2H2 acetylene 74‐86‐2 HCCH acetylene C9H8O4 acetylsalicylic acid 50‐78‐2 H2C(CH)CN acrylonitrile C3H7NO2 Ala C3H7NO2 alanine 56‐41‐7 NaAlSi3O3 albite AlSb aluminium antimonide 25152‐52‐7 AlAs aluminium arsenide 22831‐42‐1 AlBO2 aluminium borate 61279‐70‐7 AlBO aluminium boron oxide 12041‐48‐4 AlBr3 aluminium bromide 7727‐15‐3 AlBr3•6H2O aluminium bromide hexahydrate 2149397 AlCl4Cs aluminium caesium tetrachloride 17992‐03‐9 AlCl3 aluminium chloride (anhydrous) 7446‐70‐0 AlCl3•6H2O aluminium chloride hexahydrate 7784‐13‐6 AlClO aluminium chloride oxide 13596‐11‐7 AlB2 aluminium diboride 12041‐50‐8 AlF2 aluminium difluoride 13569‐23‐8 AlF2O aluminium difluoride oxide 38344‐66‐0 AlB12 aluminium dodecaboride 12041‐54‐2 Al2F6 aluminium fluoride 17949‐86‐9 AlF3 aluminium fluoride 7784‐18‐1 Al(CHO2)3 aluminium formate 7360‐53‐4 1 of 75 Chemical Abstract Chemical Formula Chemical Name Service (CAS) Number Al(OH)3 aluminium hydroxide 21645‐51‐2 Al2I6 aluminium iodide 18898‐35‐6 AlI3 aluminium iodide 7784‐23‐8 AlBr aluminium monobromide 22359‐97‐3 AlCl aluminium monochloride
    [Show full text]
  • Safety Data Sheet Acc
    Page 1/6 Safety Data Sheet acc. to OSHA HCS Printing date 01/23/2014 Reviewed on 10/15/2012 1 Identification Product identifier Product name: Calcium iodide, anhydrous Stock number: 22395 CAS Number: 10102-68-8 EC number: 233-276-8 Relevant identified uses of the substance or mixture and uses advised against. Identified use: SU24 Scientific research and development Details of the supplier of the safety data sheet Manufacturer/Supplier: Alfa Aesar, A Johnson Matthey Company Johnson Matthey Catalog Company, Inc. 30 Bond Street Ward Hill, MA 01835-8099 Tel: 800-343-0660 Fax: 800-322-4757 Email: [email protected] www.alfa.com Information Department: Health, Safety and Environmental Department Emergency telephone number: During normal hours the Health, Safety and Environmental Department at (800) 343-0660. After normal hours call Carechem 24 at (866) 928-0789. 2 Hazard(s) identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 GHS07 Skin Irrit. 2 H315 Causes skin irritation. Eye Irrit. 2A H319 Causes serious eye irritation. Classification according to Directive 67/548/EEC or Directive 1999/45/EC Xi; Irritant R36/38: Irritating to eyes and skin. Information concerning particular hazards for human and environment: Not applicable Hazards not otherwise classified No information known. Label elements Labelling according to Regulation (EC) No 1272/2008 The substance is classified and labeled according to the CLP regulation. Hazard pictograms GHS07 Signal word Warning Hazard statements H315 Causes skin irritation. H319 Causes serious eye irritation. Precautionary statements P280 Wear protective gloves/protective clothing/eye protection/face protection.
    [Show full text]