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Do You Still Need Aspirin? LifeExtension.com Stay Healthy, Live Better August 2019 Faster, Longer, More Restful SLEEP Enhance Male Sexual Health PQQ Refreshes Brain Energy Maintain Healthy Coagulation Balance Carotenoids to Protect Eye and Brain Function Omega-3 Intake Associated with Lower Mortality Risk REJUVENATE YOUR SKIN FROM WITHIN Restore Collagen AND Hyaluronic Acid WITH DELIGHTFUL GUMMIES Oral ingestion of collagen peptides and hyaluronic acid boosts these rejuvenating factors in normal, aging skin. Clinical results reveal improved skin elasticity, increased moisture, and a % reduction in the depth of eye wrinkles. The new Gummy Science™ Youthful Collagen formula provides clinically studied* doses with daily intake of tasty chewable gummies. For full product description and to order Gummy Science™ Youthful Collagen, call --- or visit www.LifeExtension.com Item # • gummies gummiess jar $. * Skin Pharmacol Physiol. ;():-. * Skin Pharmacol Physiol. ;():-. VERISOL® and Bioactive Collagen Peptides® are registered trademarks of GELITA AG. jars $ each These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Table of Contents Volume Twenty Five / Number Eight • August 2019 REPORTS 38 ENHANCE MALE SEXUAL HEALTH A ginger-like root was shown to improve sexual health in 61.5% of male participants in a published study. 46 PQQ REVITALIZES CELLULAR ENERGY A nutrient called PQQ helps grow new mitochondria in aging cells. The result is more energy in human studies and increased lifespan (in animal studies). 57 LUTEIN AND ZEAXANTHIN IMPROVE COGNITION Lutein and zeaxanthin are plant carotenoids known for protecting the eyes. New studies reveal they also increase brain processing speed, visual memory, cognitive 28 ON THE COVER flexibility, and brain blood flow. FALL TO SLEEP FASTER… 62 REMOVE DEAD SKIN CELLS STAY SLEEPING LONGER Dead cells and impurities on the skin’s surface clog pores, Three plant-based extracts create blemishes, and cause a dull, uneven appearance. work on multiple sleep centers A facial mask containing zinc, sulfur, camphor, and in the brain. A human study salicylic acid provides unique exfoliating and deep- showed a remission of cleansing effects. insomnia in 85% of subjects. DEPARTMENTS 7 AS WE SEE IT 77 HEALTHY EATING The FDA approved low-dose aspirin Chef Enrique Olvera’s internationally in 1998 to prevent platelet clumping in acclaimed restaurant in Mexico high-risk heart patients. Recent studies City serves wide-ranging haute show that aspirin may not be needed cuisine, but his latest cookbook, to reduce heart attack/stroke risk in Tu Casa Mi Casa, is based on the today’s healthier American population simple, home-cooked dishes of his groups. Low-risk adults who control childhood. We provide a handful their vascular risk factors may no longer of recipes for you to try. need the anti-thrombotic and anti- inflammatory effects of daily low-dose 83 SUPERFOODS aspirin. Rosemary is an herb rich in poly- phenols, flavonoids, and terpenes. 19 IN THE NEWS These compounds appear to be Omega-3 intake lowers mortality risk; behind its benefits for eye and brain intermittent fasting suppresses weight health, protection against stroke, gain; quercetin and dasatinib benefit and control of blood sugar levels. pulmonary fibrosis; berry metabolite improves IBD; and more. 85 AUTHOR INTERVIEW In his updated book, Grain Brain, 71 WELLNESS PROFILE David Perlmutter, MD, explains At age 67, bodybuilding champion, how blood sugar determines brain author, motivational speaker, and life health, how insulin resistance coach Wendy Ida now helps people relates to Alzheimer’s risk, and how transform their lives and bodies— gluten sensitivity is a key culprit in after a long journey to save herself. brain disease. AUGUST 2019 | LIFE EXTENSION | 1 AUGUST 2019 • Volume Twenty Five • Number Eight VoluPublisherme Twenty • LE Fo Publications,ur / Number Inc.Twelve Connect with Editorial Life Extension Editor-in-Chief • Philip Smith on the Web! Executive Managing Editor • Renee Price Medical Editor • Hernando Latorre, MD, MSc Senior Editor • Dan Jewel Senior StaffWriter • Michael Downey Department Editor • Laurie Mathena Facebook.com/LifeExtension Associate Editor • Rivka Rosenberger, EdD For instant access to special offers and Creative Director • Robert Vergara promotions, product news, and exclusive Art Director • Alexandra Maldonado health and wellness information. Chief Medical Officer Steven Joyal, MD Chief Scientific Officer Twitter.com/LifeExtension Andrew Swick, MS, PhD For up-to-the-minute health tips, Scientific Advisory Board breaking industry news, and the Örn Adalsteinsson, PhD • Richard Black, DO • John Boik, PhD • Aubrey de Grey, PhD latest updates in medical research. Frank Eichhorn, MD • Deborah F. Harding, MD • Steven B. Harris, MD • Sandra C. Kaufmann, MD Peter H. Langsjoen, MD, FACC • Dipnarine Maharaj, MD • Ralph W. Moss, PhD Customer care is available to take your calls Michael D. Ozner, MD, FACC • Jonathan V. Wright, MD, Xiaoxi Wei, PhD 24 hours a day, 7 days a week. Contributors Jonathan Chasen • Michael Downey • Katherine DeMateo • Gary Goldfaden, MD Visit the Life Extension Robert Goldfaden • Kathy Honem • Laurie Mathena • David Perlmutter, MD Nutrition Center Store Advertising • The Most Complete Line of Life Extension Supplements Vice President of Marketing • Rey Searles • [email protected] • Blood Testing and Analysis National Advertising Manager • JT Hroncich • 404-347-4170 • Personal Consultation with Life Extension Product/Wellness Specialist Senior Director of Sales and Business Development Carolyn Bouchard • [email protected] • 954-202-7685 East Cypress Creek Rd. Circulation & Distribution N Life Extension • 3600 West Commercial Blvd., Fort Lauderdale, FL 33309 Life Extension 2 Nutrition Center Editorial offices: 954-766-8433 • fax: 954-491-5306 Ocean Highway Customer Service: 800-678-8989 l antic l Email: [email protected] Federa At Wellness specialists: 800-226-2370 • Wellness email: [email protected] East Commercial Blvd. At Life Extension Magazine® we value your opinion and welcome feedback. Please mail your comments to Life Extension Magazine, Nutritiont iti CenterC t off FlFloridaid , Inc. Attn: Letters to the Editor, PO Box 407198, Fort Lauderdale, FL 33340 5990 North Federal Highway, or email us: [email protected] Fort Lauderdale, FL 33308-2633 • 954-766-8144 Monday-Friday 9 am-8 pm, #1 Rated Catalog/Internet Merchant—3-Time Winner Saturday 9 am-6 pm, Sunday 11 am-5 pm Ratings based on results of the 2019 ConsumerLab.com Survey of Supplement Users. More information at www.consumerlab.com/survey2018. LIFE EXTENSION (ISSN 1524-198X) Vol. 25, No. 8 ©2019 is published monthly except bi-monthly in April by LE Publications, Inc. at 3600 West Commercial Blvd., Fort Lauderdale, FL 33309-3338. LE Publications, Inc. All rights reserved. Published 13 times a year. Subscription rate: $40 per year in the United States. US $47 in Canada. US $60 in other countries. Mail subscriptions or address changes to: LE Publications, Inc., P. O. Box 407198, Fort Lauderdale, FL 33340-7198, USA. Or phone us toll-free at: 1-800-841-5433. Canada Subscrip- tions: Publications mail agreement number 40028967. Return undeliverable Canadian addresses to PO Box 503, RPO West Beaver Creek, Richmond Hill, ON L4B4R6. You will be sent your first issue within six weeks after LE Publications, Inc. receives your subscription fee. Periodicals Postage paid at Fort Lauderdale, FL and at additional mailing offices. POSTMASTER: Send address changes to Life Extension, P. O. Box 407198, Ft. Lauderdale, Florida 33340-7198, USA. Printed in USA. The articles in this magazine are intended for informational purposes only. They are not intended to replace the attention or advice of a physician or other health-care professional. Anyone who wishes to embark on any di- etary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition should first consult with and seek clearance from a qualified health-care professional. LEGAL NOTICE: Health claims contained in articles and advertisements in this publication have not been approved by the FDA with the exception of FDA-approved, qualified health claims for calcium, antioxidant vitamins, folic acid and EPA and DHA omega-3 fatty acids, and selenium as noted where applicable. Life Extension Magazine® does not endorse any of the businesses or the products and/or services that may appear in advertisements for non-Life Extension branded products or services contained in it, except to state that they are advertisers who may have paid Life Extension for placement of an advertisement in this publication. Life Extension disclaims any and all responsibilities or warranties as to the accuracy of information contained in advertisements for non-Life Extension branded products or services. For Canadian customers send change of address information and blocks of undeliverable copies to P. O. Box 1051, Fort Erie, ON L2A 6C7. 2 | LIFE EXTENSION | AUGUST 2019 NAD+ Cell Regenerator TM TURN ON YOUR CELLULAR ENERGY NAD+ levels plummet with age but increase in response to nicotinamide riboside. Optimized NAD+ Cell Regenerator™ combines mg of nicotinamide riboside with resveratrol and other plant extracts. 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