DOCSLIB.ORG

Scientists Honored for Research Unveiling Molecular Machines the Month of May Brought the Good Prestigious Honors in Science

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Scientists Honored for Research Unveiling Molecular Machines the Month of May Brought the Good Prestigious Honors in Science june 2012 volume 8, issue 3 Advancing Biomedical Science, Education, and Health Care Scientists honored for research unveiling molecular machines The month of May brought the good prestigious honors in science. On the Campylobacter, which together cause chains of amino acids are formed into news that two School of Medicine 29th, Arthur L. Horwich, m.d., was most of the world’s food-borne illness. three-dimensional, functional struc- scientists, each of whom have done named a winner of the Shaw Prize Galán’s group has thoroughly tures. Misfolded proteins have been pathbreaking work on molecular ma- in Life Science and Medicine, along characterized the Salmonella “needle implicated in many diseases, including chines involved in human disease, had with his longtime scientific col- complex,” a syringe-like organelle Alzheimer’s disease and amyotrophic received high honors for their research. laborator Franz-Ulrich Hartl, m.d., through which the bacterium injects lateral sclerosis (als). On May 1 Jorge E. Galán, ph.d., dr.med., of the Max Planck Institute bacterial proteins into host cells during In 1989, Horwich’s lab, in collabo- d.v.m., chair and Lucille P. Markey of Biochemistry in Germany. infection, modulating the function ration with Hartl and his postdoctoral Professor of Microbial Pathogenesis Galán is renowned for his research of those cells for its own advantage. mentor Walter Neupert m.d., ph.d., and professor of cell biology, was elect- on the cell biology, biochemistry, im- In 2004, Galán and colleagues used discovered a specialized protein in yeast ed a member of the National Academy munobiology, and structural biology of cryoelectron microscopy to visualize called Hsp60 that acts as a protein- of Sciences (nas), one of the most the bacterial pathogens Salmonella and the three-dimensional structure of the folding machine. Horwich and col- needle complex. For his wide-ranging leagues went on to elucidate how such research, in 2011 he was awarded the machines work by studying a related Koch Prize, the leading international bacterial protein called GroEL. By 1993, scientific award in microbiology. in a collaboration with the late Yale The nas, an organization of sci- X-ray crystallographer Paul B. Sigler, entists and engineers dedicated to the ph.d., the atomic structure of GroEL— furtherance of science and its use for a “beautiful work of nature,” in Hor- the general welfare, was established in wich’s words—had been deciphered. 1863. The Academy acts as an official The Shaw Prizes carry a monetary adviser to the federal government in award of $1 million (U.S.) and are any matter of science or technology. given by the Hong Kong-based Shaw Also elected to the nas in May Prize Foundation for achievement in was John R. Carlson, ph.d., of the the life sciences, astronomy, and math- Department of Cellular, Molecular, ematics. Established in 2002 by film- and Developmental Biology in Yale’s maker and philanthropist Run Run Faculty of Arts and Sciences, bringing Shaw, the awards are “dedicated to the total number of nas members at furthering societal progress, enhancing Yale to 63. quality of life, and enriching humani- harold shapiro harold Horwich, an nas member since ty’s spiritual civilization.” Horwich and Jorge Galán (left), who has studied the molecular basis of infection by Salmonella and other food- borne pathogens, was elected to the National Academy of Sciences. Arthur Horwich shares the 2003, has devoted his career to un- Hartl will receive the award in Hong Shaw Prize in Life Science and Medicine for his contributions to understanding protein folding. derstanding protein folding—how Kong in September. Student research on heart surgery gets a boost from new endowment In the 1960s, when cardiac surgery W.L. Glenn, m.d., then chief of the heart defects—and he trained numer- was still a young field, Horace C. cardiac surgery section. ous physician- scientists who went on to Stansel Jr., m.d., was already making “As a junior faculty colleague, head surgery departments around the his mark at Yale as a skillful, innova- I learned a great deal from Stan,” country. “Stan personified the com- tive pediatric heart surgeon. A mem- recalls John E. Fenn, m.d., now clini- mitment to life-long learning that is so ber of the School of Medicine faculty cal professor of surgery at the medical necessary to medicine,” says Fenn. until his death in 1994, Stansel built a school. “He was a skilled surgeon To carry on Stansel’s legacy, the reputation as a consummate physi- who could think on his feet. He was Stansel family recently established an cian, researcher, and educator, and a master at knowing how to get out endowment that will provide support was a mentor to generations of medi- of trouble in the operating room, to Yale medical students conducting cal students and residents. and colleagues often called on him research in cardiac surgery. Known Known as “Stan” to friends and for assistance.” as the Horace C. Stansel Jr. Research colleagues, Stansel trained with Stansel also pushed the boundaries Fund, the endowment will provide courtesy of doris stansel Ormand C. Julian, m.d., at Presby- of surgical technique—the Damus- one- and two-year fellowships to Pediatric heart surgeon Horace Stansel, seen terian St. Luke’s Hospital in Chicago Kaye-Stansel procedure is still used by students with financial need, allowing in a 1978 photo with a patient, was a widely and was recruited to Yale by William pediatric surgeons to treat congenital them to pursue research // Gift (page 8) admired physician, researcher, and educator. Non-Profit Org. inside this issue 1 Church St., Suite 300, New Haven, CT 06510-3330 U. S. Postage www.medicineatyale.org 2 Lifelines paid Since her first foray into research on the New Haven, CT brain bases of nicotine addiction, neurosci- Permit No. 526 entist Marina Picciotto has been “hooked.” 3 Primary care—and much more Research in Yale’s Section of General Inter- nal Medicine shapes health care worldwide. 5 Cancer: a new day Results from a clinical trial show the goal of immunotherapy may be within reach. also Advances, pp. 3, 5 Out & About, p. 4 Grants and Contracts, pp. 6–7 @YaleMed f /YaleMed lifelines New section chief to be appointed for Otolaryngology Wendell G. Yarbrough, m.d., will be Marina Picciotto’s research not only sheds light on nico- named chief of tine’s effects on the brain, the Section of but also has implications for Otolaryngology for other important health at the School of issues, such as controlling Medicine and obesity and the development Wendell of effective pain medica- Yale-New Haven Yarbrough tions that do not lead to Hospital (ynhh). drug dependence. He will also be director of the head and neck cancer program at Smilow Cancer Hospital at Yale-New Haven as well as the co-director of the molecular virol- ogy research program at Yale Cancer Center (ycc). Yarbrough, whose appoint- Marina Picciotto michael marsland ment begins August 1, comes to Yale from Vanderbilt University, where he is professor of otolaryn- gology and cancer biology and di- Making sense of addiction rector of the Barry Baker Labora- tory of Head and Neck Oncology. transport of ions across nerve cell them,” Picciotto says. For instance, Neuroscientist is focused He is also the Ingram Professor membranes. “It was very satisfying, in 2011, she and lab member Yann S. of Cancer Research and co-leader on the brain bases of because you could actually say, ‘this Mineur, ph.d., associate research scien- of the thoracic and head and neck goes with this’ [and make] pictures tist, teamed up with colleagues in the tobacco dependence program at the Vanderbilt Ingram that made sense. But I was always Section of Comparative Medicine to Cancer Center. sneakily trying to get back to [the show that a specific type of nicotinic Marina Picciotto, ph.d., says that while Yarbrough’s research con- question], What do those molecules receptor is the crucial trigger for nico- she was growing up in Manhattan, she centrates on the identifi cation of mean for complex behaviors?” tine’s effects on appetite suppression was “one of those scattered people tumor suppressors in head and It’s a question that has driven Pic- and weight-loss in mice. The study, who did well in school but got yelled neck cancers and the understand- ciotto’s research ever since. As a post- published in Science, could lead to new at by the teachers.” In science labs, ing of tumor growth. Recently, doctoral fellow at the Institut Pasteur in strategies to treat obesity. however, “that was never a problem.” his lab has focused on identifying Paris, France, she began studying nico- Picciotto also studies galanin, a At the magnet high school she subtypes of head and neck and tinic acetylcholine receptors (nAChRs), neuropeptide that works to modu- attended, students completed gradu- salivary cancers and the use of proteins in nerve cells that are acti- late acetylcholine but also heightens ation requirements early, and took on models that the lab has developed vated by the neurotransmitter acetyl- the effects of opiate drugs—many of full-time internships as seniors. Some- to test targeted agents. choline, but also respond to chemicals which are addictive. In 2003, she pub- what by chance, she came across an “I am confi dent that Dr. Yar- like nicotine. She describes this research lished research in Proceedings of the opening in a lab at the Rockefeller Uni- brough’s experience, leadership, the way many describe their first ciga- National Academy of Sciences showing versity, where she worked on studies and goals for head and neck cancer rette: “Once I started, I was hooked.” that in addition to increasing the pain- of feeding behavior in rats that would research and care will strengthen In 1995 she joined the School of fighting effects of opiates, galanin neatly foreshadow her later career.
Load more

Recommended publications
  • Connections Opportunities
    FY2O11Annual Report e m B r a C i n g opportunities M e M b e r s S e r v i n g t e C h n o l o g i e s o u t r e a c h M e M o r y T r a i n i n g SCIENCE D i s C o v e r y B r a i n R e s e a R c h v a l u e A d v o c A c y S u p p o r t i n g C i r C u i t i nternational m i s s i o n f u t u r e E v o l v i n g D y n a m i c a C tion Potential C o g n i t i o n f o s t e r i n g connections e m B r a C i n g opportunities f o s t e r i n g R e s e a R c h S e r v i n g o u t r e a c h SCIENCE E v o l v i n g B r Technologies v a l u e S u p p o r t i n g D y n a A d v o c A c y m i s s i o n I n t e r n a t I o n a l C i r C u i t f u t u r e M e M o r y C o g n i t i o n t r a i n i n g 2010-2011 Society for Neuroscience Council OFFICERS Susan G.
    [Show full text]
  • NRIC 2014 Event Program
    Event Program WEDNESDAY, SEPTEMBER 24 Nebraska EPSCoR: Advancing Nebraska Through Transformative Research & Workforce Development HILTON OMAHA epscor.nebraska.edu nric.nebraska.edu Message from the Nebraska EPSCoR Director Notes: Dear Participants, Welcome to the 2014 Nebraska Neuroscience Symposium. Research in the field of neuroscience continues to make dynamic discoveries, each advance yielding greater understanding of the brain: humanity’s principal resource for addressing the challenges and possibilities we face. Your interactions here are part of what moves this work forward. Nebraska EPSCoR is proud to host this gathering. EPSCoR—the Experimental Program to Stimulate Competitive Research—was created by the U.S. Congress to improve research infrastructure and capacity of a group of states. We work with research and education partners to enhance their capabilities and benefit Nebraska’s workforce development and economic growth. At today’s symposium—our 10th annual event and second devoted to neuroscience—we appreciate National Science Foundation funding in support of these important connections. Our speakers bring expertise from standout careers. We greatly value their presence and hope you enjoy the knowledge transfer and networking opportunities. F. Fred Choobineh, P.E., Ph.D. Director, Nebraska EPSCoR Table of Contents Agenda... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ... ..1 Morning Session.. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .2 Afternoon Session. 5 Poster
    [Show full text]
  • EMBO Conference Takes to the Sea Life Sciences in Portugal
    SUMMER 2013 ISSUE 24 encounters page 3 page 7 Life sciences in Portugal The limits of privacy page 8 EMBO Conference takes to the sea EDITORIAL Maria Leptin, Director of EMBO, INTERVIEW EMBO Associate Member Tom SPOTLIGHT Read about how the EMBO discusses the San Francisco Declaration Cech shares his views on science in Europe and Courses & Workshops Programme funds on Research Assessment and some of the describes some recent productive collisions. meetings for life scientists in Europe. concerns about Journal Impact Factors. PAGE 2 PAGE 5 PAGE 9 www.embo.org COMMENTARY INSIDE SCIENTIFIC PUBLISHING panels have to evaluate more than a hundred The San Francisco Declaration on applicants to establish a short list for in-depth assessment, they cannot be expected to form their views by reading the original publications Research Assessment of all of the applicants. I believe that the quality of the journal in More than 7000 scientists and 250 science organizations have by now put which research is published can, in principle, their names to a joint statement called the San Francisco Declaration on be used for assessment because it reflects how the expert community who is most competent Research Assessment (DORA; am.ascb.org/dora). The declaration calls to judge it views the science. There has always on the world’s scientific community to avoid misusing the Journal Impact been a prestige factor associated with the publi- Factor in evaluating research for funding, hiring, promotion, or institutional cation of papers in certain journals even before the impact factor existed. This prestige is in many effectiveness.
    [Show full text]
  • Jean-Pierre G. Changeux
    EDITORIAL ADVISORY COMMITTEE Marina Bentivoglio Larry F. Cahill Stanley Finger Duane E. Haines Louise H. Marshall Thomas A. Woolsey Larry R. Squire (Chairperson) The History of Neuroscience in Autobiography VOLUME 4 Edited by Larry R. Squire ELSEVIER ACADEMIC PRESS Amsterdam Boston Heidelberg London New York Oxford Paris San Diego San Francisco Singapore Sydney Tokyo This book is printed on acid-free paper. (~ Copyright 9 byThe Society for Neuroscience All Rights Reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Permissions may be sought directly from Elsevier's Science & Technology Rights Department in Oxford, UK: phone: (+44) 1865 843830, fax: (+44) 1865 853333, e-mail: [email protected]. You may also complete your request on-line via the Elsevier homepage (http://elsevier.com), by selecting "Customer Support" and then "Obtaining Permissions." Academic Press An imprint of Elsevier 525 B Street, Suite 1900, San Diego, California 92101-4495, USA http ://www.academicpress.com Academic Press 84 Theobald's Road, London WC 1X 8RR, UK http://www.academicpress.com Library of Congress Catalog Card Number: 2003 111249 International Standard Book Number: 0-12-660246-8 PRINTED IN THE UNITED STATES OF AMERICA 04 05 06 07 08 9 8 7 6 5 4 3 2 1 Contents Per Andersen 2 Mary Bartlett Bunge 40 Jan Bures 74 Jean Pierre G. Changeux 116 William Maxwell (Max) Cowan 144 John E. Dowling 210 Oleh Hornykiewicz 240 Andrew F.
    [Show full text]
  • Joshua T. Vogelstein –
    Joshua T. Vogelstein, Ph.D., Assistant Professor, JHU – Curriculum Vitae 2021/09/23 Assistant Professor, Department of Biomedical Engineering Johns Hopkins University B [email protected] Joshua T. Vogelstein Í jovo.me Personal Information Primary Appointment 08/14 – Assistant Professor, Department of Biomedical Engineering, JHU, Baltimore, MD, USA. Joint Appointments 09/19 – Joint Appointment, Department of Biostatistics, Johns Hopkins University, Baltimore, MD, USA. 08/15 – Joint Appointment, Department of Applied Mathematics and Statistics, JHU, Baltimore, MD, USA. 08/14 – Joint Appointment, Department of Neuroscience, JHU, Baltimore, MD, USA. 08/14 – Joint Appointment, Department of Computer Science, JHU, Baltimore, MD, USA. Institutional and Center Appointments 08/15 – Steering Committee, Kavli Neuroscience Discovery Institute (KNDI), Baltimore, MD, USA. 08/14 – Core Faculty, Institute for Computational Medicine, JHU, Baltimore, MD, USA. 08/14 – Core Faculty, Center for Imaging Science, JHU, Baltimore, MD, USA. 08/14 – Assistant Research Faculty, Human Language Technology Center of Excellence, JHU, Balti- more, MD, USA. 10/12 – Affiliated Faculty, Institute for Data Intensive Engineering and Sciences, JHU, Baltimore, MD, USA. Education & Training 2003 – 2009 Ph.D in Neuroscience, Johns Hopkins School of Medicine, Advisor: Eric Young, Thesis: OOPSI: a family of optical spike inference algorithms for inferring neural connectivity from population calcium imaging . 2009 – 2009 M.S. in Applied Mathematics & Statistics, Johns Hopkins University. 1998 – 2002 B.A. in Biomedical Engineering, Washington University, St. Louis. Academic Experience 08/18 – Director of Biomedical Data Science Focus Area, Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. 05/16 – Visiting Scientist, Howard Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.
    [Show full text]
  • 9Th Annual Enhancing Neuroscience Diversity Through Undergraduate Research Education Experiences (ENDURE) Meeting
    9th Annual Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (ENDURE) Meeting October 19, 2019 | Chicago, IL The NIH Office of the Director and these NIH Institutes and Centers participate in the NIH Blueprint for Neuroscience Research: • NCATS • NIAAA • NIDCR • NINR • NCCIH • NIBIB • NIEHS • OBSSR • NEI • NICHD • NIMH • NIA • NIDA • NINDS TABLE OF CONTENTS ENDURE PROGRAM AND MEETING GOALS .................................................................................. 2 NOTICE OF INTENT TO RE-ISSUE BP-ENDURE FOA ...................................................................... 3 ENDURE MEETING AGENDA ........................................................................................................ 4 NIH BLUEPRINT WELCOME AND SPEAKER BIOGRAPHIES .......................................................... 5 ENDURE PROGRAM INFORMATION AND TRAINEE RESEARCH ABSTRACTS • BP-ENDURE AT HUNTER AND NYU ........................................................................................ 8 • BP-ENDURE AT ST. LOUIS: A NEUROSCIENCE PIPELINE ....................................................... 23 • BRAiN: BUILDING RESEARCH ACHIEVEMENT IN NEUROSCIENCE ......................................... 41 • BRIDGE TO THE PH.D. IN NEUROSCIENCE ............................................................................ 48 • ENHANCING NEUROSCIENCE DIVERSITY WITH TENNESSEE STATE UNIVERSITY – NEUROSCIENCE EDUCATION AND RESEARCH VANDERBILT EXPERIENCE (TSU-NERVE)...... 57 • NEUROSCIENCE RESEARCH OPPORTUNITIES TO
    [Show full text]
  • 1 Achieving a Fair and Effective COVID-19 Response: an Open
    1 Achieving A Fair and Effective COVID-19 Response: An Open Letter to Vice-President Mike Pence, and Other Federal, State, and Local Leaders from Public Health and Legal Experts in the United States Sustained human-to-human transmission of the novel coronavirus in the United States (US) appears today inevitable. The extent and impact of the outbreak in the US is difficult to predict and will depend crucially on how policymakers and leaders react. It will depend particularly on whether there is adequate funding and support for the response; fair and effective management of surging health care demand; careful and evidence-based mitigation of public fear; and necessary support and resources for fair and effective infection control. A successful American response to the COVID-19 pandemic must protect the health and human rights of everyone in the US. One of the greatest challenges ahead is to make sure that the burdens of COVID-19, and our response measures, do not fall unfairly on people in society who are vulnerable because of their economic, social, or health status. We write as experts in public health, law, and human rights, with experience in previous pandemic responses, to set forth principles and practices that should guide the efforts against COVID-19 in the US. It is essential that all institutions, public and private, address the following critical concerns through new legislation, institutional policies, leadership and spending. ADEQUATE FUNDING AND SUPPORT FOR THE RESPONSE MUST BE PROVIDED ● Federal, state and local governments should act immediately to allocate funds to ensure that necessary measures can be carried out and that basic human needs continue to be met as the epidemic unfolds.
    [Show full text]
  • 2015/2016 IMP Research Report
    RESEARCH REPORT 2015–2016 Cover: Connective tissue cells of axolotl finger. (see also p. 34) CONTENTS 02 Highlights 04 Introduction Jan-Michael Peters & Harald Isemann 06 Facts & Figures 8 Current Research 10 Meinrad Busslinger 12 Tim Clausen 14 Luisa Cochella 16 Wulf Haubensak 18 David Keays 20 Thomas Marlovits 22 Anna Obenauf 24 Andrea Pauli 26 Rushad Pavri 28 Jan-Michael Peters 30 Alexander Stark 32 Andrew Straw 34 Elly Tanaka 36 Alipasha Vaziri 38 Stefan Westermann 40 Manuel Zimmer 42 Johannes Zuber 44 What the group leaders say 46 In-house Services 48 BioOptics 49 Bioinformatics 50 Molecular Biology Service 51 Max Perutz Library 52 Mass Spectrometry and Protein Chemistry 53 Comparative Medicine and Transgenic Services 56 The IMP and the VBC 57 Scientific Advisory Board 58 Vienna Biocenter Core Facilities (VBCF) 60 Vienna Biocenter training programme 62 IMP seminar series 66 IMP’s awards and honours 68 Publications 74 Sponsors & partners 76 Imprint IMP RESEARCH REPORT 2015–2016 HIGHLIGHTS As of late 2016, the IMP has a new home. The move marks the grand finale in a series of highlights that the institute enjoyed in 2015/16. The scientific JANUARY Max-Birnstiel Lecture by the search committee for the milestones of the IMP 2015 James Allison of the MD Anderson first IMP Director in the 1980s. are often marked Cancer Center in Houston, Texas: Jeff Schatz passes away not long by publications, “Boosting the Immune System after the lecture, in October 2015. awards, grants and to Fight Cancer”. honours, or talks Max-Birnstiel Lecture by by distinguished MARCH Dignitaries from IMP, Ruslan Medzhitov, Professor of guest lecturers in our 2015 Boehringer Ingelheim, the city of Immunobiology at Yale School on-going seminar Vienna and others gather for of Medicine in New Haven, series.
    [Show full text]
  • The Receptors
    The Receptors Volume 26 Series Editor Giuseppe Di Giovanni Department of Physiology & Biochemistry Faculty of Medicine and Surgery, University of Malta, Malta. The Receptors book Series, founded in the 1980’s, is a broad-based and wellrespected series on all aspects of receptor neurophysiology. The series presents published volumes that comprehensively review neural receptors for a specifi c hormone or neurotransmitter by invited leading specialists. Particular attention is paid to in-depth studies of receptors’ role in health and neuropathological processes. Recent volumes in the series cover chemical, physical, modeling, biological, pharmacological, anatomical aspects and drug discovery regarding different receptors. All books in this series have, with a rigorous editing, a strong reference value and provide essential up-to-date resources for neuroscience researchers, lecturers, students and pharmaceutical research. More information about this series at http://www.springer.com/series/7668 Robin A.J. Lester Editor Nicotinic Receptors Editor Robin A.J. Lester Department of Neurobiology University of Alabama at Birmingham Birmingham , AL , USA ISBN 978-1-4939-1166-0 ISBN 978-1-4939-1167-7 (eBook) DOI 10.1007/978-1-4939-1167-7 Springer New York Heidelberg Dordrecht London Library of Congress Control Number: 2014947538 © Springer Science+Business Media New York 2014 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed.
    [Show full text]
  • Eisch CV 083119 Webpage
    Amelia J. Eisch, Ph.D. Curriculum Vitae, 31 August 2019 Tenured Professor Mail address: Abramson Research Center University of Pennsylvania Perelman School of Medicine (PennMed) and Room 402F Children's Hospital of Philadelphia (CHOP) Research Institute 3615 Civic Center Blvd. Email: [email protected], [email protected], Philadelphia, PA 19104-4318 or [email protected] Physical address: 68 Osler Circle Office telephone: (215) 590-1931 Philadelphia, PA 19104 EDUCATION Yale University, New Haven, CT 1986-1990 Bachelor of Arts in Psychology with Biology Track, cum laude University of California at Irvine, Irvine, CA 1990-1997 Doctor of Philosophy in Biological Sciences, received June 1997 Department of Psychobiology Yale University Medical School, New Haven, CT 1997-2000 Department of Psychiatry Postdoctoral Fellowship RESEARCH EXPERIENCE AND EMPLOYMENT UnderGraduate Research, Advisor, Dr. Richard J. Gerrig 1988-1989 Department of Psychology, Yale University: Memory retrieval during language comprehension UnderGraduate Research, Advisor, Dr. J. Steve Reznick 1988-1989 Department of Psychology, Yale University: Shyness in infant twins UnderGraduate Honors Research Thesis, Advisor, Dr. Mark A. Riddle 1989-1990 Child Study Center, Yale University Medical Center Socioeconomic impact on symptomatology in Gilles de la Tourette’s syndrome Doctoral Thesis, Research, and TeachinG Assistant, Advisor, Dr. John F. Marshall 1990-1997 Department of Psychobiology, University of California at Irvine Neuronal consequences of repeated administration of
    [Show full text]
  • Else Kröner Fresenius Award 3
    Zum 25. Todestag von Else Kröner Else Kröner Fresenius2013 Award 2 Else Kröner Fresenius Award 3 Liebe Leser, liebe Freunde und Partner der Else Kröner-Fresenius-Stiftung, mit Freude und Dankbarkeit geben wir Prof. Dr. Ruslan Medzhitov als Preisträger des Else Kröner Fresenius Awards bekannt. Seine For- schung wird unsere Vorstellungen von der Reaktion des Körpers auf Inhalt Infektionen neu definieren. 3 Editorial Ende 2011 beschloss die Else Kröner-Fresenius-Stiftung, zum 25. Todestag ihrer Stifterin ein außergewöhnliches Förderprojekt 4 Preisträger Ruslan Medzhitov: auszuloben: einen substanziellen, zukunftsgerichteten Forschungspreis Weit über die Immunologie hinaus auf einem der spannendsten Gebiete der medizinischen Forschung. Dieser Award soll nicht nur die Werte Else Kröners veranschaulichen, 11 Interview: Warum fühlen wir uns krank sondern auch die Bandbreite ihres Lebenswerks als Unternehmerin bei einem Infekt? und Stifterin. In Erfüllung von Else Kröners Wünschen richtet sich die Stiftungs- 14 Laudatio für Ruslan Medzhitov arbeit sowohl auf wissenschaftliche Inhalte als auch auf begabte junge Forscher. Ausschreibungen für Stipendien, Forschungspreise, Dokto- 16 Die Auswahl des Preisträgers randen- und Forschungskollegs – verschiedene Maßnahmen zielen da- rauf ab, engagierten Forschern Räume zu erschließen und Talente zur 17 Die Jury des Else Kröner Fresenius Awards Entfaltung zu bringen. Der Else Kröner Fresenius Award zeichnet herausragende Forschungs- In ihr Tagebuch schrieb die junge 20 Den Nachwuchs im Blick ergebnisse aus und fördert bedeutende Arbeiten in der Zukunft. Da- Pharmaziestudentin 1948, was zu bei entstehen auch Ausbildungsmöglichkeiten für junge Forscher. Wir einem Leitmotiv ihres Lebens wurde: 22 Sieben Rätsel der Immunologie möchten zeigen, dass in der medizinischen Forschung auch in jungen »Die Wissenschaft will erobert Jahren viel erreicht werden kann und dass die Wissenschaft attraktive sein.« Else Kröner erkannte schon 24 Grafik: Im Kampf gegen Infektionen Karrierewege bietet.
    [Show full text]
  • A Young Scientist Scores Another First
    july/august 2011 volume 7, issue 3 Advancing Biomedical Science, Education, and Health Care Couple’s passion for the arts inspires unique scholarship fund Having majored in philosophy and Association and a Jungian psychoana- to contributions from others, includ- history as an undergraduate at Trinity lyst and psychiatrist in private practice ing a matching gift from the School of College, in Hartford, Conn., David in San Francisco. Medicine to mark the school’s Bicen- Leof, m.d., a member of the School But Leof’s terror quickly evapo- tennial year. of Medicine’s Class of 1964, initially rated, and “as things unfolded, I was Another major influence on Leof found life at the medical school to be just like a little kid at Christmas,” he was Lippard’s successor as dean, “quite terrifying.” On his very first says. “I had an absolutely joyful time Frederick C. Redlich, m.d., a leg- day, then-Dean Vernon W. Lip- in medical school.” endary chair of the Department of pard, m.d., issued a sobering call to In gratitude, Leof and his wife, Psychiatry from 1950 to 1967 who responsibility, reminding the new Colleen, have made a bequest to the built the department into one of the students that medical school is only a School of Medicine of several million nation’s finest. It was Redlich, Leof brief chapter in the life of a physician. dollars, which will support medi- says, who encouraged him to go into Though the day would come when cal students who have distinguished psychiatry himself. After graduating, each student would receive a medical themselves in the arts or humani- Leof interned at Dartmouth College’s degree, “you have the rest of your life ties.
    [Show full text]