Anti-ASAP2 (aa 5-194) polyclonal antibody (DPABH-00543) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Antigen Description Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.

Immunogen Synthetic peptide, corresponding to a region within N terminal amino acids 5-194 of Human PAG3 (UniProt ID: O43150-2).

Isotype IgG

Source/Host Rabbit

Species Reactivity Mouse, Human

Purification Immunogen affinity purified

Conjugate Unconjugated

Applications WB

Format Liquid

Size 100 μl

Buffer pH: 7.00; Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol

Preservative None

Storage Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

GENE INFORMATION

Gene Name ASAP2 ArfGAP with SH3 domain, and PH domain 3 [ Homo sapiens ]

Official Symbol ASAP2

Synonyms ASAP2; ArfGAP with SH3 domain, ankyrin repeat and PH domain 2; PAP; PAG3; AMAP2; DDEF2; SHAG1; CENTB3; Pap-alpha; arf-GAP with SH3 domain, ANK repeat and PH domain-

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved containing 2; centaurin, beta 3; PYK2 C terminus-associated protein; pyk2 C-terminus- associated protein; development and differentiation enhancing factor 2; development and differentiation-enhancing factor 2; paxillin-associated protein with ARF GAP activity 3;

Entrez Gene ID 8853

Protein Refseq NP_001128663.1

UniProt ID O43150

Pathway Arf6 trafficking events; Endocytosis; Fc gamma R-mediated phagocytosis;

Function ARF GTPase activator activity; enzyme activator activity; protein binding; zinc ion binding

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 2 © Creative Diagnostics All Rights Reserved