Extracellular Onchocerca-Derived Small Rnas in Host
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Classification of Parasites BLY 459 First Lab Test (October 10, 2010)
Classification of Parasites BLY 459 First Lab Test (October 10, 2010) If a taxonomic name is not in bold type, you will not be held responsible for it on the lab exam. Terms and common names that may be asked are also listed. I have attempted to be consistent with the taxonomic schemes in your text as well as to list all slides and live specimens that were displayed. In addition to highlighted taxa, be familiar with, material in lab handouts (especially proper nomenclature), lab display sheets, as well as material presented in lecture. Questions about vectors and locations within hosts will be asked. Be able to recognize healthy from infected tissue. Phylum Platyhelminthes (Flatworms) Class Turbellaria Dugesia (=Planaria ) Free-living, anatomy, X-section Bdelloura horseshoe crab gills Class Monogenea Gyrodactylus , Neobenedenis, Ergocotyle gills of freshwater fish Neopolystoma urinary bladder of turtles Class Trematoda ( Flukes ) Subclass Digenea Life-cycle stages: Recognize miracidia, sporocyst, redia, cercaria , metacercaria, adults & anatomy, model Order ?? Hirudinella ventricosa wahoo stomach Nasitrema nasal cavity of bottlenose dolphin Order Strigeiformes Family Schistosomatidae Schistosoma japonicum adults, male & female, liver granuloma & healthy liver, ova, cercariae, no metacercariae, adults in mesenteric intestinal veins Order Echinostomatiformes Family Fasciolidae Fasciola hepatica sheep & human liver, liver fluke Order Plagiorchiformes Family Dicrocoeliidae Dicrocoelium & Eurytrema Cure for All Diseases by Hulda Clark, Paragonimus -
Worms, Nematoda
University of Nebraska - Lincoln DigitalCommons@University of Nebraska - Lincoln Faculty Publications from the Harold W. Manter Laboratory of Parasitology Parasitology, Harold W. Manter Laboratory of 2001 Worms, Nematoda Scott Lyell Gardner University of Nebraska - Lincoln, [email protected] Follow this and additional works at: https://digitalcommons.unl.edu/parasitologyfacpubs Part of the Parasitology Commons Gardner, Scott Lyell, "Worms, Nematoda" (2001). Faculty Publications from the Harold W. Manter Laboratory of Parasitology. 78. https://digitalcommons.unl.edu/parasitologyfacpubs/78 This Article is brought to you for free and open access by the Parasitology, Harold W. Manter Laboratory of at DigitalCommons@University of Nebraska - Lincoln. It has been accepted for inclusion in Faculty Publications from the Harold W. Manter Laboratory of Parasitology by an authorized administrator of DigitalCommons@University of Nebraska - Lincoln. Published in Encyclopedia of Biodiversity, Volume 5 (2001): 843-862. Copyright 2001, Academic Press. Used by permission. Worms, Nematoda Scott L. Gardner University of Nebraska, Lincoln I. What Is a Nematode? Diversity in Morphology pods (see epidermis), and various other inverte- II. The Ubiquitous Nature of Nematodes brates. III. Diversity of Habitats and Distribution stichosome A longitudinal series of cells (sticho- IV. How Do Nematodes Affect the Biosphere? cytes) that form the anterior esophageal glands Tri- V. How Many Species of Nemata? churis. VI. Molecular Diversity in the Nemata VII. Relationships to Other Animal Groups stoma The buccal cavity, just posterior to the oval VIII. Future Knowledge of Nematodes opening or mouth; usually includes the anterior end of the esophagus (pharynx). GLOSSARY pseudocoelom A body cavity not lined with a me- anhydrobiosis A state of dormancy in various in- sodermal epithelium. -
Software for Taxon-Aware Analysis of Clustered Protein Sequences
G3: Genes|Genomes|Genetics Early Online, published on September 2, 2017 as doi:10.1534/g3.117.300233 INVESTIGATIONS KinFin: Software for taxon-aware analysis of clustered protein sequences Dominik R. Laetsch∗,†,1 and Mark L. Blaxter∗ ∗Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3JT UK, †The James Hutton Institute, Errol Road, Dundee DD2 5DA UK ABSTRACT The field of comparative genomics is concerned with the study of similarities and differences KEYWORDS between the information encoded in the genomes of organisms. A common approach is to define gene bioinformatics families by clustering protein sequences based on sequence similarity, and analyse protein cluster presence protein orthology and absence in different species groups as a guide to biology. Due to the high dimensionality of these data, protein family downstream analysis of protein clusters inferred from large numbers of species, or species with many genes, evolution is non-trivial, and few solutions exist for transparent, reproducible and customisable analyses. We present comparative KinFin, a streamlined software solution capable of integrating data from common file formats and delivering genomics aggregative annotation of protein clusters. KinFin delivers analyses based on systematic taxonomy of the filarial nema- species analysed, or on user-defined groupings of taxa, for example sets based on attributes such as life todes history traits, organismal phenotypes, or competing phylogenetic hypotheses. Results are reported through graphical and detailed text output files. We illustrate the utility of the KinFin pipeline by addressing questions regarding the biology of filarial nematodes, which include parasites of veterinary and medical importance. We resolve the phylogenetic relationships between the species and explore functional annotation of proteins in clusters in key lineages and between custom taxon sets, identifying gene families of interest. -
Monophyly of Clade III Nematodes Is Not Supported by Phylogenetic Analysis of Complete Mitochondrial Genome Sequences
UC Davis UC Davis Previously Published Works Title Monophyly of clade III nematodes is not supported by phylogenetic analysis of complete mitochondrial genome sequences Permalink https://escholarship.org/uc/item/7509r5vp Journal BMC Genomics, 12(1) ISSN 1471-2164 Authors Park, Joong-Ki Sultana, Tahera Lee, Sang-Hwa et al. Publication Date 2011-08-03 DOI http://dx.doi.org/10.1186/1471-2164-12-392 Peer reviewed eScholarship.org Powered by the California Digital Library University of California Park et al. BMC Genomics 2011, 12:392 http://www.biomedcentral.com/1471-2164/12/392 RESEARCHARTICLE Open Access Monophyly of clade III nematodes is not supported by phylogenetic analysis of complete mitochondrial genome sequences Joong-Ki Park1*, Tahera Sultana2, Sang-Hwa Lee3, Seokha Kang4, Hyong Kyu Kim5, Gi-Sik Min2, Keeseon S Eom6 and Steven A Nadler7 Abstract Background: The orders Ascaridida, Oxyurida, and Spirurida represent major components of zooparasitic nematode diversity, including many species of veterinary and medical importance. Phylum-wide nematode phylogenetic hypotheses have mainly been based on nuclear rDNA sequences, but more recently complete mitochondrial (mtDNA) gene sequences have provided another source of molecular information to evaluate relationships. Although there is much agreement between nuclear rDNA and mtDNA phylogenies, relationships among certain major clades are different. In this study we report that mtDNA sequences do not support the monophyly of Ascaridida, Oxyurida and Spirurida (clade III) in contrast to results for nuclear rDNA. Results from mtDNA genomes show promise as an additional independently evolving genome for developing phylogenetic hypotheses for nematodes, although substantially increased taxon sampling is needed for enhanced comparative value with nuclear rDNA. -
Helminthology Nematodes Strongyloides.Pdf
HelminthologyHelminthology –– NematodesNematodes StrongyloidesStrongyloides TerryTerry LL DwelleDwelle MDMD MPHTMMPHTM ClassificationClassification ofof NematodesNematodes Subclass Order Superfamily Genus and Species Probable (suborder) prevalence in man Secernentea Rhabditida Rhabditoidea Strongyloides stercoralis 56 million Stronglyloides myoptami Occasional Strongyloides fuelloborni Millions Strongyloides pyocyanis Occasional GeneralGeneral InformationInformation ► PrimarilyPrimarily aa diseasedisease ofof tropicaltropical andand subtropicalsubtropical areas,areas, highlyhighly prevalentprevalent inin Brazil,Brazil, Columbia,Columbia, andand SESE AsiaAsia ► ItIt isis notnot uncommonuncommon inin institutionalinstitutional settingssettings inin temperatetemperate climatesclimates ((egeg mentalmental hospitals,hospitals, prisons,prisons, childrenchildren’’ss homes)homes) ► SeriousSerious problemproblem inin thosethose onon immunosuppressiveimmunosuppressive therapytherapy ► HigherHigher prevalenceprevalence inin areasareas withwith aa highhigh waterwater tabletable GeneralGeneral RecognitionRecognition FeaturesFeatures ► Size;Size; parasiticparasitic femalefemale 2.72.7 mm,mm, freefree livingliving femalefemale 1.21.2 mm,mm, freefree livingliving malemale 0.90.9 mmmm ► EggsEggs –– 5050--5858 XX 3030--3434 umum ► TheThe RhabdiformRhabdiform larvaelarvae havehave aa shortershorter buccalbuccal canalcanal vsvs hookwormhookworm ► LarvaeLarvae havehave aa doubledouble laterallateral alaealae,, smallersmaller thanthan hookwormhookworm ► S.S. -
Some Immunological and Other Studies in Mice on Infection with Embryonated Eggs of Toxocara Canis (Werner, 1782)
This dissertation has been 69-11,668 microfilmed exactly as received MALIK, Prem Dutt, 1918- SOME IMMUNOLOGICAL AND OTHER STUDIES IN MICE ON INFECTION WITH EMBRYONATED EGGS OF TOXOCARA CANIS (WERNER, 1782). The Ohio State University, Ph.D., 1968 Agriculture, animal pathology Health Sciences, immunology University Microfilms, Inc., Ann Arbor, Michigan SOME IMMUNOLOGICAL AND OTHER STUDIES IN MICE ON INFECTION WITH EMBRYONATED EGGS OF TOXOCARA CANIS (WERNER, 1782) DISSERTATION Presented in Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy in the Graduate School of The Ohio State University By Prem Dutt Malik, L.V.P., B.V.Sc., M.Sc ****** The Ohio State University 1968 Approved by Adviser / Department of Veterinary Parasitology ACKNOWLEDGMENTS I wish to express my earnest thanks to my adviser, Dr. Fleetwood R. Koutz, Professor and Chairman, Department of Veterinary Parasitology, for planning a useful program of studies for me, and ably guiding my research project to a successful conclusion. His wide and varied experience in the field of Veterinary Parasitology came handy to me at all times during the conduct of this study. My grateful thanks are expressed to Dr. Harold F. Groves, for his sustained interest in the progress of this work, and careful scrutiny of the manuscript. Thanks are extended to Dr. Walter G. Venzke, for making improvements in the manuscript. Dr. Marion W. Scothorn deserves my thanks for his wholehearted cooperation. To Dr. Walter F. Loeb, I am really indebted for his valuable time in taking pictures of the eggs, the larvae, and the spermatozoa of Toxocara canis. The help of Mr. -
Entomopathogenic Nematodes (Nematoda: Rhabditida: Families Steinernematidae and Heterorhabditidae) 1 Nastaran Tofangsazi, Steven P
EENY-530 Entomopathogenic Nematodes (Nematoda: Rhabditida: families Steinernematidae and Heterorhabditidae) 1 Nastaran Tofangsazi, Steven P. Arthurs, and Robin M. Giblin-Davis2 Introduction Entomopathogenic nematodes are soft bodied, non- segmented roundworms that are obligate or sometimes facultative parasites of insects. Entomopathogenic nema- todes occur naturally in soil environments and locate their host in response to carbon dioxide, vibration, and other chemical cues (Kaya and Gaugler 1993). Species in two families (Heterorhabditidae and Steinernematidae) have been effectively used as biological insecticides in pest man- agement programs (Grewal et al. 2005). Entomopathogenic nematodes fit nicely into integrated pest management, or IPM, programs because they are considered nontoxic to Figure 1. Infective juvenile stages of Steinernema carpocapsae clearly humans, relatively specific to their target pest(s), and can showing protective sheath formed by retaining the second stage be applied with standard pesticide equipment (Shapiro-Ilan cuticle. et al. 2006). Entomopathogenic nematodes have been Credits: James Kerrigan, UF/IFAS exempted from the US Environmental Protection Agency Life Cycle (EPA) pesticide registration. There is no need for personal protective equipment and re-entry restrictions. Insect The infective juvenile stage (IJ) is the only free living resistance problems are unlikely. stage of entomopathogenic nematodes. The juvenile stage penetrates the host insect via the spiracles, mouth, anus, or in some species through intersegmental membranes of the cuticle, and then enters into the hemocoel (Bedding and Molyneux 1982). Both Heterorhabditis and Steinernema are mutualistically associated with bacteria of the genera Photorhabdus and Xenorhabdus, respectively (Ferreira and 1. This document is EENY-530, one of a series of the Department of Entomology and Nematology, UF/IFAS Extension. -
Extracellular Onchocerca-Derived Small Rnas in Host Nodules
Edinburgh Research Explorer Extracellular Onchocerca -derived small RNAs in host nodules and blood Citation for published version: Quintana, JF, Makepeace, BL, Babayan, SA, Ivens, A, Pfarr, KM, Blaxter, M, Debrah, A, Wanji, S, Ngangyung, HF, Bah, GS, Tanya, VN, Taylor, DW, Hoerauf, A & Buck, AH 2015, 'Extracellular Onchocerca -derived small RNAs in host nodules and blood', Parasites and Vectors, vol. 8, no. 1, 58. https://doi.org/10.1186/s13071-015-0656-1 Digital Object Identifier (DOI): 10.1186/s13071-015-0656-1 Link: Link to publication record in Edinburgh Research Explorer Document Version: Publisher's PDF, also known as Version of record Published In: Parasites and Vectors Publisher Rights Statement: © 2015 Quintana et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. General rights Copyright for the publications made accessible via the Edinburgh Research Explorer is retained by the author(s) and / or other copyright owners and it is a condition of accessing these publications that users recognise and abide by the legal requirements associated with these rights. Take down policy The University of Edinburgh has made every reasonable effort to ensure that Edinburgh Research Explorer content complies with UK legislation. If you believe that the public display of this file breaches copyright please contact [email protected] providing details, and we will remove access to the work immediately and investigate your claim. -
Second Case of Zoonotic Onchocerca Infection in a Resident of Oita in Japan
Article available at http://www.parasite-journal.org or http://dx.doi.org/10.1051/parasite/1996032179 S e c o n d c a s e o f z o o n o t ic O n c h o c e r c a in f e c t io n IN A RESIDENT OF OlTA IN JAPAN TAKAOKA H.*, BAIN O.**, TAJIMI S.***, KASHIMA K.****, NAKAYAMA I.****, KORENAGA M.*****, AOKI C.* & OTSUKA Y.* Summary : Résumé : D euxièm e cas d ’infection d ’un habitant d ’O ïta , au A non-gravid female Onchocerca was found in histopathological J apon, par une onchocerque animale sections of a biopsy specimen taken from a painful nodule in the A Oïta, au sud du Japon, une femme consulte pour un nodule wrist of a 57-year-old woman in Oita, in southern Japan. Six sous-cutané douloureux au poignet accompagné d'une paralysie species of Onchocerca have been found in animals in Japan: two récente de la main. Une onchocerque femelle, non gravide, est in wild bovids, one in equids, and three in domestic bovids of trouvée sur les coupes histologiques de la biopsie. which one, Onchocerca sp., is only known by the microfilaria and Six espèces d'onchocerques sont signalées au Japon: deux chez infective stage. Distinctive morphological features of the worm, un bovidé sauvage en montagne, une chez les chevaux, trois including a three-layered thick cuticle with prominent annular chez les bovins domestiques dont une, Onchocerca sp., connue ridges at wide intervals, high somatic muscles and narrow lateral seulement par la microfilaire et le stade infectant. -
World Report on Vision
World report on vision A World report on vision © World Health Organization 2019 Some rights reserved. This work is available under the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 IGO licence (CC BY-NC-SA 3.0 IGO; https:// creativecommons.org/licenses/by-nc-sa/3.0/igo). Under the terms of this licence, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use of the WHO logo is not permitted. If you adapt the work, then you must license your work under the same or equivalent Creative Commons licence. If you create a translation of this work, you should add the following disclaimer along with the suggested citation: “This translation was not created by the World Health Organization (WHO). WHO is not responsible for the content or accuracy of this translation. The original English edition shall be the binding and authentic edition”. Any mediation relating to disputes arising under the licence shall be conducted in accordance with the mediation rules of the World Intellectual Property Organization. Suggested citation. World report on vision. Geneva: World Health Organization; 2019. Licence: CC BY-NC-SA 3.0 IGO. Cataloguing-in-Publication (CIP) data. CIP data are available at http://apps.who.int/ iris. Sales, rights and licensing. To purchase WHO publications, see http://apps.who.int/ bookorders. To submit requests for commercial use and queries on rights and licensing, see http://www.who.int/about/licensing. -
Onchodermatitis: Where Are We Now?
Tropical Medicine and Infectious Disease Review Onchodermatitis: Where Are We Now? Michele E. Murdoch Department of Dermatology, West Herts Hospitals NHS Trust, Vicarage Road, Watford, Hertfordshire WD18 0HB, UK; [email protected]; Tel.: +44-1923-217139 Received: 30 July 2018; Accepted: 28 August 2018; Published: 1 September 2018 Abstract: Onchocerciasis causes debilitating pruritus and rashes as well as visual impairment and blindness. Prior to control measures, eye disease was particularly prominent in savanna areas of sub-Saharan Africa whilst skin disease was more common across rainforest regions of tropical Africa. Mass drug distribution with ivermectin is changing the global scene of onchocerciasis. There has been successful progressive elimination in Central and Southern American countries and the World Health Organization has set a target for elimination in Africa of 2025. This literature review was conducted to examine progress regarding onchocercal skin disease. PubMed searches were performed using keywords ‘onchocerciasis’, ‘onchodermatitis’ and ‘onchocercal skin disease’ over the past eight years. Articles in English, or with an English abstract, were assessed for relevance, including any pertinent references within the articles. Recent progress in awareness of, understanding and treatment of onchocercal skin disease is reviewed with particular emphasis on publications within the past five years. The global burden of onchodermatitis is progressively reducing and is no longer seen in children in many formerly endemic foci. Keywords: onchodermatitis; onchocercal skin disease; onchocerciasis; ivermectin 1. Introduction Onchocerciasis, caused by infection with the filarial worm Onchocerca volvulus, is one of the eleven neglected tropical diseases (NTDs) recently targeted for elimination by the World Health Organization (WHO) [1]. -
The Biology of Strongyloides Spp.* Mark E
The biology of Strongyloides spp.* Mark E. Viney1§ and James B. Lok2 1School of Biological Sciences, University of Bristol, Bristol, BS8 1TQ, UK 2Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104-6008, USA Table of Contents 1. Strongyloides is a genus of parasitic nematodes ............................................................................. 1 2. Strongyloides infection of humans ............................................................................................... 2 3. Strongyloides in the wild ...........................................................................................................2 4. Phylogeny, morphology and taxonomy ........................................................................................ 4 5. The life-cycle ..........................................................................................................................6 6. Sex determination and genetics of the life-cycle ............................................................................. 8 7. Controlling the life-cycle ........................................................................................................... 9 8. Maintaining the life-cycle ........................................................................................................ 10 9. The parasitic phase of the life-cycle ........................................................................................... 10 10. Life-cycle plasticity .............................................................................................................