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CNS Spectrums CNS Spectrums http://journals.cambridge.org/CNS Additional services for CNS Spectrums: Email alerts: Click here Subscriptions: Click here Commercial reprints: Click here Terms of use : Click here The following abstracts were presented as posters at the 2015 NEI Psychopharmacology Congress CNS Spectrums / Volume 21 / Issue 01 / February 2016, pp 77 - 121 DOI: 10.1017/S1092852915000905, Published online: 22 February 2016 Link to this article: http://journals.cambridge.org/abstract_S1092852915000905 How to cite this article: (2016). The following abstracts were presented as posters at the 2015 NEI Psychopharmacology Congress. CNS Spectrums, 21, pp 77-121 doi:10.1017/S1092852915000905 Request Permissions : Click here Downloaded from http://journals.cambridge.org/CNS, IP address: 12.12.207.2 on 15 Mar 2016 CNS Spectrums (2016), 21,77–121. © Cambridge University Press 2016 doi:10.1017/S1092852915000905 ABSTRACTS The following abstracts were presented as posters at the 2015 NEI Psychopharmacology Congress Congratulations to the scientific poster winners of the 2015 NEI Psychopharmacology Congress! st 1 PLACE: Tardive Dyskinesia in the Era of Second Generation Antipsychotics: A Case Report and Literature Review (page 22) nd 2 PLACE: Comparing Deep Brain Stimulation (DBS) and ECT for Treatment Resistant Depression in Elderly Population (page 37) rd 3 PLACE: The Complex Multimodal Management of First-Psychotic Episode in Patients with Morphometric Alteration in Hippocampal Formation (page 30) Violent Video Games – Physiological and variability, emotion, sleep quality, violent video game, Psychological Impact on Children and desensitization, aggressiveness”. Adolescents: Literature Review RESULTS: Literature so far shows an association between Sree Latha Krishna Jadapalle, MD1 and Monifa daily exposure to violent video games and number of Seawell, MD1 depressive and anxiety symptoms among pre-adolescent youth. The physiological changes observed in the 1 Morehouse School of Medicine, Atlanta, GA prolonged violent video play group are increased ABSTRACT: Background: Video games became popular in perception of emotional sadness, lower sleep quality the US in the 1980s. Approximately 145 million Americans and increased alertness during the sleep, higher heart play video games regularly and 42% of households have a rate and higher low frequency/high frequency (sympa- video game system. 70% of children 2 to 18 years old have a thetic predominence) during sleep. There is building game system in their home. In American children, game use evidence that prolonged violent videogame play is increased from an average of 4 hours per week at the end of significantly related to drastic increases in adolescents' 1980s to a current average of 13 hours per week. Recent course of aggressive behavior, thoughts and affect; school shootings involving young perpetrators with history increased physiological arousal; and decreased pro- of playing violent video games raised a high alert on further social (helping) behavior over time. Also, there are investigating the association between violent video game use studies showing no predictive relationship established and actual violence. American Academy of Pediatrics (AAP) between violent video game play and aggressiveness. and AACAP proposed that children learn by observing, CONCLUSION: The results cannot be generalized due to mimicking and adopting behaviors, which has been the basic lack of standardized conceptualization, poor methodol- principle of social learning model. Literature also supports ogies applied, differences in the sample populations and the idea that prolonged exposure to violent video games can lack of consideration to cultural differences contributing desensitize the youth by emotionally blunting them. Neuro to the social and peer support in some of the studies. imaging studies so far showed common neural substrates The review highlights the further requirement of such as the prefrontal cortex and the limbic system being large controlled prospective studies including diverse involved in aggression and violent video games exposure. ethnicities and also neuroimaging studies in pediatric OBJECTIVES: To understand the physiological and psycho- population to understand the causality. logical impacts of violent video games on children and adolescents; To understand the neurobiology of aggres- Lamotrigine for the Treatment of Restless LEG sion and its association with violent video games. Syndrome 1 METHODS: Literature review of 12 peer reviewed journal Vithyalakshmi Selvaraj, MD ; Babuji R. Gandra, 2 1 articles dated from 2010 to 2014 was collected, com- MBBS ; Palanikumar Gunasekar, MBBS and Imad 1 piled, and analyzed. The key words used for searching Alsakaf, MD databases for articles pertaining to the topic included, 1 Creighton University School of Medicine, Omaha, NE but was not limited to, “children, adolescent, heart rate 2 Essentia Health-Duluth Clinic, Duluth, MN http://journals.cambridge.org Downloaded: 15 Mar 2016 IP address: 12.12.207.2 78 ABSTRACTS ABSTRACT: Lamotrigine is Food and Drug Administration Mean dose of buprenorphine at the time of onset of approved for maintenance treatment in bipolar disorder symptoms was 19.7 ± 6.6 mg/day. Fifty (50%) of the type I, partial and generalized seizures. Restless legs subjects accepted bethanechol for urinary symptoms syndrome (RLS) is a neurological condition either while the rest increased fluid intake and symptoms idiopathic or secondarily associated with conditions such subsided over time. Average dose of bethanechol was as iron deficiency, folate deficiency, uremia, pregnancy, 25mg twice a day. 80% of the patients who did receive Parkinson’s disease, diabetes mellitus, and rheumatoid bethanechol noted resolution of urinary symptoms after arthritis. The estimated prevalence of RLS is 7% to 10%. 6 months and were no longer on bethanechol. Dopaminergic agents are first-line therapy for RLS CONCLUSIONS: although anticonvulsants are increasingly used with Urinary hesitancy is a known side effect of success. We present a case of RLS successfully treated buprenorphine due to the agonism at the mu opioid with lamotrigine. To the best of our knowledge only two receptor leading to detrusor and urinary sphincter muscle reports of a similar occurrence have been published. contraction. However, this side effect is often under recognized and may go untreated. It may lead to significant discomfort and could possibly interfere with patient Buprenorphine-Induced Urinary Hesitancy may compliance with buprenorphine treatment. In most cases be Transient and Easy to Treat the symptoms are mild and transient and can easily be treated with increased fluid intake and use of bethanechol, Anjali Varma, MD1,2,3,4; Mamta Sapra, MD1,2 and Joseph Iskandar, DO3 a cholinergic drug that has long been used for non- obstructive urinary hesitancy or retention, at low doses. 1 Salem VA Medical Center, Mental Health Clinic, Salem, VA IMPACT: Office based treatment of opioid dependence 2 Virginia Tech Carilion School of Medicine, Roanoke, with buprenorphine/naloxone combination used for VA maintenance continues to increase among veterans as 3 University of Virginia School of Medicine, we fight the opioid epidemic. Since urinary hesitancy is Charlottesville, VA typically an early and transient side effect, patients need 4 Edward Via College of Osteopathic Medicine, to be educated about the symptoms being short lasting Blacksburg, VA and treated as needed with fluids and bethanechol. This ABSTRACT: Objectives: A retrospective study to examine is likely to enhance compliance and lower risk of relapse the prevalence of urinary hesitancy in veterans being of this highly vulnerable population. Symptoms subsided treated with buprenorphine/naloxone for opioid depen- over time and increased fluid intake in the other 50% of dence and explore the relationship between dose and the patients who declined or decided to defer treatment duration of treatment with these symptoms and other with bethanechol as noted below. patient and treatment factors. METHODS: One hundred seventeen charts of veterans with A Preliminary Investigation of the Influence of a diagnosis of opioid dependence who have received the Adverse Side Effects of Medications on treatment with buprenorphine since September 2009 to Adherence to Medications in Patients with March 2012 in the Buprenorphine Clinic at Salem VA Depression medical center was conducted. The chart review Azeez A Lawal included socio-demographic information, history of opioid addiction, buprenorphine dose, duration of College of Medicine of the University of Lagos, Lagos, buprenorphine treatment, side effects of treatment, Nigeria prevalence of urinary hesitancy, duration and treatments ABSTRACT: used for its management, other prescribed medications, Depression is a state of low mood and aversion ’ comorbid medical diagnoses and pertinent laboratory to activity that can affect a person s thoughts, behavior, results. feelings and sense of well-being. Adherence to medica- tion is a problem in this group of patients because of the RESULTS: Of the 117 charts reviewed, 105 met inclusion symptomatology. It is therefore necessary to know if criteria for the study. Mean age of subjects was 40.5 ± there are factors that can influence adherence to 12 yrs. 36.5% of the patients reported no side effects, medication in depressed patients. The objective of the 22% patients reported urinary hesitancy. Mean age of study was to assess the preliminary investigation of
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