microorganisms Article An Increase in the Levels of Middle Surface Antigen Characterizes Patients Developing HBV-Driven Liver Cancer Despite Prolonged Virological Suppression Giuseppina Brancaccio 1,†, Romina Salpini 2,†, Lorenzo Piermatteo 2 , Matteo Surdo 3, Vanessa Fini 3, Luna Colagrossi 4, Marco Cantone 5, Arianna Battisti 2, Yasunori Oda 6, Domenico Di Carlo 7, Francesca Ceccherini-Silberstein 2, Carlo Federico Perno 4, Giovanni Battista Gaeta 5,‡ and Valentina Svicher 2,*,‡ 1 Infectious Diseases, University Hospital of Padua, 35128 Padua, Italy;
[email protected] 2 Department of Experimental Medicine, Tor Vergata University, 00133 Rome, Italy;
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[email protected] (F.C.-S.) 3 Molecular Genetics Laboratory, Eurofins Genoma, 00138 Rome, Italy;
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[email protected] (V.F.) 4 Department of Diagnostic Medicine and Laboratory, Bambin Gesù Children’s Hospital, 00165 Rome, Italy;
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[email protected] (C.F.P.) 5 Department of Mental Health and Public Medicine, Section of Infectious Diseases, University of Campania “Luigi Vanvitelli”, 81100 Naples, Italy;
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[email protected] (G.B.G.) 6 Citation: Brancaccio, G.; Salpini, R.; Beacle Inc., Kyoto 600-8305, Japan;
[email protected] 7 Paediatric Clinical Research Center “Romeo and Enrica Invernizzi”, University of Milan, 26900 Milan, Italy; Piermatteo, L.; Surdo, M.; Fini, V.;
[email protected] Colagrossi, L.; Cantone, M.; Battisti, * Correspondence:
[email protected] A.; Oda, Y.; Di Carlo, D.; et al. An † First author equally contributed. Increase in the Levels of Middle ‡ Joint last author.