Libro De Abstract

Total Page:16

File Type:pdf, Size:1020Kb

Libro De Abstract SPECIAL THANKS EMPRESAS COLABORADORAS SEV VI R O L O G Í A Publicación Oficial de la Sociedad Española de Virología 13th Spanish National Congress Of Virology Madrid 2015 CONGRESO NACIONAL DE Volumen 18 Número 1/2015 EXTRAORDINARIO VIROLOGÍA . PUBLICACIÓN OFICIAL DE LA SOCIEDAD ESPAÑOLA DE VIROLOGÍA 13th Spanish National Congress Of Virology Madrid 2015 Del 7 al 10 de junio de 2015 Auditorio de la Fábrica Nacional de Moneda y Timbre Real Casa de la Moneda de Madrid Volumen 18 Madrid 2015 Número 1/2015 EXTRAORDINARIO Edición y Coordinación: M Angeles Muñoz-Fernández &M. Dolores García-Alonso Diseño y Maquetación: DM&VCH.events.S.L. Diseño Portada: M. Dolores García-Alonso Impresión: Fragma: Servicios de impresión digital en Madrid ISSN (versión digital): 2172-6523 SEV – Sociedad Española de Virología Centro de Biología Molecular “Severo Ochoa” C/ Nicolás Cabrera, 1 28049 Cantoblanco – Madrid [email protected] Página web del congreso: www.congresonacionalvirologia2015.com La responsabilidad del contenido de las colaboraciones publicadas corresponderá a sus autores, quienes autorizan la reproducción de sus artículos a la SEV exclusivamente para esta edición. La SEV no hace necesariamente suyas las opiniones o los criterios expresados por sus colaboradores. Virología. Publicación Oficial de la Sociedad Española de Virología XIII CONGRESO NACIONAL DE VIROLOGÍA B I E N V E N I D A El Comité Organizador del XIII Congreso Nacional de Virología (XIII CNV) tiene el placer de comunicaros que éste se celebrará en Madrid, del 7 al 10 de junio de 2015. En el XIII CNV participan conjuntamente la Sociedad Española de Virología (SEV) y la Sociedad Italiana de Virología (SIV), y estará abierto13th a Spanish la participación National de virólogos de Latinoamérica. La SEV, la SIV y el Comité Organizador os da la bienvenida.Congress Of Virology El Acto Inaugural del Congreso se celebrará en el Ateneo de Madrid el día 7 de Junio y laMadrid sede del2015 Congreso será el Ayre Gran Hotel Colón de Madrid y la Fábrica Nacional de Moneda y Timbre - Real Casa de la Moneda en las Sesiones de los días 8 al 10 de Junio. El Ayre Gran Hotel Colón y la Fábrica Nacional de Moneda y Timbre - Real Casa de la Moneda se ubican junto al famoso Parque del Retiro y el Palacio de Deportes. Los miembros del Comité Organizador y Científico hemos diseñado un Programa Científico atractivo, contando con la presencia de virólogos españoles y extranjeros de reconocido prestigio, cubriendo los diversos campos de la virología, básicos, aplicados, traslacional y clínicos en sus vertientes humana, animal y vegetal. También se muestra la interacción de la virología con otras áreas de la biología, la medicina, la nanotecnología, la informática, la química o la física. El programa científico ha buscado que estén representadas las distintas áreas de la virología y os sintáis identificados, de tal forma que participéis de forma activa y enviéis comunicaciones. Todos los asistentes podremos discutir sobre los avances, logros y retos en el estudio de los virus, para generar nuevas ideas y promover la investigación entre la comunidad de virólogos, en un Congreso que esperamos sea fructífero y distendido. Para que los jóvenes tengan una mayor presencia, se ha destinado una Sesión a presentaciones rápidas, no mas de tres minutos, las denominadas "flash presentations" en las que en breve tiempo, como si de un anuncio se tratara, deberéis defender y difundir el gran trabajo que estáis desarrollando. Agradecemos a los miembros del Comité Organizador y del Comité Científico del XIII Congreso Nacional de Virología su esfuerzo e ilusión en la preparación de este importante Evento, especialmente al personal del Hospital General Universitario Gregorio Marañón y de otras instituciones de Madrid por su ayuda con los temas locales. Hacemos extensivo nuestro agradecimiento al Presidente y a los miembros de la Junta Directiva de la Sociedad Española de Virología por el apoyo que nos han prestado desde el inicio de los preparativos. También agradecemos a todas las instituciones participantes y empresas colaboradoras en este XIII Congreso Nacional de la Sociedad Española de Virología como patrocinadores, ya que sin su apoyo hubiera sido imposible realizar este Evento tan importante para la virología. Finalmente, Madrid ofrece los atractivos turísticos de una moderna capital europea. Por lo tanto, sería una gran satisfacción para nosotros si marcarais estas fechas en vuestras agendas. Deseamos que todos disfrutéis de este Congreso. Un cordial saludo en nombre del Comité Organizador, Mª Angeles Muñoz-Fernández, Presidenta del Comité Organizador del XIII CNV Volumen 18 – Número 1/2015 - EXTRAORDINARIO XIII CONGRESO NACIONAL DE VIROLOGÍA W E L C O M E The Organizing Committee of the 13th National Virology Congress (CNV) are pleased to announce that the Congress will be held from 7th to 10th June, 2015 at the Ateneo de Madrid where the Opening Session will take place. Whereas the Scientific Sessions from 8th to 10th June will be held at the Fábrica Nacional de 13th Spanish National Moneda y Timbre - Real Casa de la Moneda, the building of which is located next toCongress the famous Of Virology Retiro Park and Palacio de los Deportes. The 13th CNV will have great pleasure to host the Italian Society for Virology (SIV) together with the Spanish Society for Virology (SEV). The participation of virologists from LatinMadrid America 2015 will be especially welcom. The SEV, the SIV and the Organizing Committee hope that you will enjoy the Congress in Madrid and exploit the opportunity to interact with your colleagues. The members of the Organizing and Scientific Committees have planned an attractive Scientific Programme with the presence of Spanish and foreign virologists of recognized prestige that will cover various fields of basic, applied, translational and clinical aspects of human, veterinary and plant virology. The programme will also cover the fruitful interactions of virology with other areas of biology, medicine, nanotechnology, computing, chemistry and physics. We hope that basic and clinical researchers working in any branch of virology will be interested in submitting abstracts and actively participating in this Congress. All together, we will be able to discuss current progress, achievements and challenges in the study of viruses with the aim of generating new ideas and promoting research among the community of virologists, in a Congress that we hope will be both a fruitful and relaxed. To make the participation for young researchers in the scientific sessions easy, short (3 minutes) "flash-presentation" sessions have been scheduled in the Scientific Programme. We would like to thank the Scientific and Organizing Committees of this 13th National Congress of Virology for the enthusiasm and effort in the preparation of this important event. We are especially grateful to the staff of the Hospital General Universitario Gregorio Marañón and other institutions of Madrid for their help with the local issues. We extend our thanks to the President and the Executive Board of the Spanish Society of Virology for the support to this Congress. Moreover, we gratefully acknowledge the sponsorship of several institutions and companies: the 13th CNV would have not been possible without their support. Moreover, we believe that Madrid will offer you all the tourist attractions of a modern European capital. Therefore, it would be great pleasure for us if you could mark these dates in your agenda With my best regards on behalf of the Organizing Committee, Mª Angeles Muñoz-Fernández Chairwoman of the Organizing Committee of the 13th CNV. Virología. Publicación Oficial de la Sociedad Española de Virología XIII CONGRESO NACIONAL DE VIROLOGÍA ABREVIATURAS TOPICS PS: SESIÓN PLENARIA (Invited plenary lecture) PS: PLENARY SESSION (Invited plenary lecture) P: CONFERENCIAS PLENARIAS P: PLENARY LECTURE OP: PRESENTACIONES ORALES (Invited paper) OP: ORAL PRESENTATIONS (Invited paper) CO: PRESENTACIONES ORALES CO: ORAL PRESENTATIONS 13th Spanish National PO: SESIÓN POSTERS PO: POSTERS SESSION Congress Of Virology ÍNDICE TABLE OF CONTENTSMadrid 2015 Páginas Pages COMITES 5 COMMITTEES 5 PROGRAMA-VERSIÓN REDUCIDA 13 PROGRAMME-REDUCED VERSION 13 PROGRAMA 19 PROGRAMME 19 ABSTRACT SESIONES PLENARIAS 31 ABSTRACT PLENARY SESSION 31 SESIÓN PLENARIA I: FRONTIERS IN VIROLOGY 33 (PI): FRONTIERS IN VIROLOGY 33 SESIÓN PLENARIA II: EMERGING VIRUSES 36 (PII): EMERGING VIRUSES 36 PRESENTACIÓN ORAL I: EMERGING VIRUSES 38 (OP I): EMERGING VIRUSES 38 SESIÓN PLENARIA III: HEPATITIS A, B AND C: BASIC, 40 (P III): HEPATITIS A, B AND C: BASIC, TRANSLATIONAL 40 TRANSLATIONAL AND CLINICAL RESEARCH AND CLINICAL RESEARCH SESIÓN PLENARIA IV: INNATE IMMUNITY 44 (P IV): INNATE IMMUNITY 44 PRESENTACIÓN ORAL II: INNATE IMMUNITY 44 (OP II): INNATE IMMUNITY 44 SESIÓN PLENARIA V: STRUCTURAL ANALYSIS OF VIRUS 47 (P V): STRUCTURAL ANALYSIS OF VIRUS AND 47 AND BIOTECHNOLOGY BIOTECHNOLOGY PRESENTACIÓN ORAL III: STRUCTURAL ANALYSIS OF 49 (OP III): STRUCTURAL ANALYSIS OF VIRUS AND 49 VIRUS AND BIOTECHNOLOGY BIOTECHNOLOGY SESIÓN PLENARIA VI: PLANT VIRUS 51 (P VI): PLANT VIRUS 51 SESIONES PARALELAS 55 PARALLEL SESSION 55 SESIÓN PARALELA I: EMERGING VIRUSES AND 55 PARALLEL SESSION I: EMERGING VIRUSES AND 55 VETERINARY (CO 9 – CO 16) VETERINARY (CO 9 – CO 16) SESIÓN PARALELA II: HIV (CO 17 – CO 24) 62 PARALLEL SESSION II: HIV (CO 17 – CO 24) 62 SESIÓN PARALELA III: PLANT VIRUS 70 PARALLEL SESSION III: PLANT VIRUS 70 (CO 25 – CO 32) (CO 25 – CO 32) SESIÓN PARALELA IV: ANIMAL
Recommended publications
  • The Viruses of Wild Pigeon Droppings
    The Viruses of Wild Pigeon Droppings Tung Gia Phan1,2, Nguyen Phung Vo1,3,A´ kos Boros4,Pe´ter Pankovics4,Ga´bor Reuter4, Olive T. W. Li6, Chunling Wang5, Xutao Deng1, Leo L. M. Poon6, Eric Delwart1,2* 1 Blood Systems Research Institute, San Francisco, California, United States of America, 2 Department of Laboratory Medicine, University of California San Francisco, San Francisco, California, United States of America, 3 Pharmacology Department, School of Pharmacy, Ho Chi Minh City University of Medicine and Pharmacy, Ho Chi Minh, Vietnam, 4 Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, A´ NTSZ Regional Institute of State Public Health Service, Pe´cs, Hungary, 5 Stanford Genome Technology Center, Stanford, California, United States of America, 6 Centre of Influenza Research and School of Public Health, University of Hong Kong, Hong Kong SAR Abstract Birds are frequent sources of emerging human infectious diseases. Viral particles were enriched from the feces of 51 wild urban pigeons (Columba livia) from Hong Kong and Hungary, their nucleic acids randomly amplified and then sequenced. We identified sequences from known and novel species from the viral families Circoviridae, Parvoviridae, Picornaviridae, Reoviridae, Adenovirus, Astroviridae, and Caliciviridae (listed in decreasing number of reads), as well as plant and insect viruses likely originating from consumed food. The near full genome of a new species of a proposed parvovirus genus provisionally called Aviparvovirus contained an unusually long middle ORF showing weak similarity to an ORF of unknown function from a fowl adenovirus. Picornaviruses found in both Asia and Europe that are distantly related to the turkey megrivirus and contained a highly divergent 2A1 region were named mesiviruses.
    [Show full text]
  • Computational Exploration of Virus Diversity on Transcriptomic Datasets
    Computational Exploration of Virus Diversity on Transcriptomic Datasets Digitaler Anhang der Dissertation zur Erlangung des Doktorgrades (Dr. rer. nat.) der Mathematisch-Naturwissenschaftlichen Fakultät der Rheinischen Friedrich-Wilhelms-Universität Bonn vorgelegt von Simon Käfer aus Andernach Bonn 2019 Table of Contents 1 Table of Contents 1 Preliminary Work - Phylogenetic Tree Reconstruction 3 1.1 Non-segmented RNA Viruses ........................... 3 1.2 Segmented RNA Viruses ............................. 4 1.3 Flavivirus-like Superfamily ............................ 5 1.4 Picornavirus-like Viruses ............................. 6 1.5 Togavirus-like Superfamily ............................ 7 1.6 Nidovirales-like Viruses .............................. 8 2 TRAVIS - True Positive Details 9 2.1 INSnfrTABRAAPEI-14 .............................. 9 2.2 INSnfrTADRAAPEI-16 .............................. 10 2.3 INSnfrTAIRAAPEI-21 ............................... 11 2.4 INSnfrTAORAAPEI-35 .............................. 13 2.5 INSnfrTATRAAPEI-43 .............................. 14 2.6 INSnfrTBERAAPEI-19 .............................. 15 2.7 INSytvTABRAAPEI-11 .............................. 16 2.8 INSytvTALRAAPEI-35 .............................. 17 2.9 INSytvTBORAAPEI-47 .............................. 18 2.10 INSswpTBBRAAPEI-21 .............................. 19 2.11 INSeqtTAHRAAPEI-88 .............................. 20 2.12 INShkeTCLRAAPEI-44 .............................. 22 2.13 INSeqtTBNRAAPEI-11 .............................. 23 2.14 INSeqtTCJRAAPEI-20
    [Show full text]
  • Viruses in Transplantation - Not Always Enemies
    Viruses in transplantation - not always enemies Virome and transplantation ECCMID 2018 - Madrid Prof. Laurent Kaiser Head Division of Infectious Diseases Laboratory of Virology Geneva Center for Emerging Viral Diseases University Hospital of Geneva ESCMID eLibrary © by author Conflict of interest None ESCMID eLibrary © by author The human virome: definition? Repertoire of viruses found on the surface of/inside any body fluid/tissue • Eukaryotic DNA and RNA viruses • Prokaryotic DNA and RNA viruses (phages) 25 • The “main” viral community (up to 10 bacteriophages in humans) Haynes M. 2011, Metagenomic of the human body • Endogenous viral elements integrated into host chromosomes (8% of the human genome) • NGS is shaping the definition Rascovan N et al. Annu Rev Microbiol 2016;70:125-41 Popgeorgiev N et al. Intervirology 2013;56:395-412 Norman JM et al. Cell 2015;160:447-60 ESCMID eLibraryFoxman EF et al. Nat Rev Microbiol 2011;9:254-64 © by author Viruses routinely known to cause diseases (non exhaustive) Upper resp./oropharyngeal HSV 1 Influenza CNS Mumps virus Rhinovirus JC virus RSV Eye Herpes viruses Parainfluenza HSV Measles Coronavirus Adenovirus LCM virus Cytomegalovirus Flaviviruses Rabies HHV6 Poliovirus Heart Lower respiratory HTLV-1 Coxsackie B virus Rhinoviruses Parainfluenza virus HIV Coronaviruses Respiratory syncytial virus Parainfluenza virus Adenovirus Respiratory syncytial virus Coronaviruses Gastro-intestinal Influenza virus type A and B Human Bocavirus 1 Adenovirus Hepatitis virus type A, B, C, D, E Those that cause
    [Show full text]
  • Mini Review Picobirnavirus: a Putative Emerging Threat to Humans And
    Advances in Animal and Veterinary Sciences Mini Review Picobirnavirus: A Putative Emerging Threat to Humans and Animals JOBIN JOSE KATTOOR, SHUBHANKAR SIRCAR, SHARAD SAURAB, SHANMUGANATHAN SUBRAMANIYAN, KULDEEP DHAMA, YASHPAL SINGH MALIK* ICAR-Indian Veterinary Research Institute, Izatnagar 243122, Bareilly, Uttar Pradesh, India. Abstract | Diarrheal diseases remain fatal threat to human and animal population with the emergence of new types of pathogens. Among them, viral gastroenteritis plays a lion share with a number ranging over 100 different types including emerging and re-emerging types of viruses. Recent viral metagenomics studies confirm the co-existence of viruses in gastrointestinal tract of several different host species. A Picobirnavirus, consisting of 2 segments, has recently attained attention due to its wide host range and genetic variability. Until 2011, these small viruses were not consid- ered as a separate virus family, when a new family (Picobirnaviridae) was approved by the International Committee on Taxonomy of Viruses (ICTV). Currently two distinct genogroups (GG-I and GG-II) and one predicted genogroup (GG-III) are included in the Picobirnaviridae family. Recently, picobirnavirus infections have been reported from al- most all species including wild animals where persistent infection of the virus is also reported. Picobirnaviruses (PBVs) are also reported as opportunistic pathogens in immuno compromised hosts including HIV infected patients. Presence of atypical picobirnaviruses with shorter genomic segments along with genetic closeness of animal and human PBVs and its ability to infect immuno-compromised hosts pose a heavy threat for all human and animal. Currently RNA dependent RNA polymerase based RT-PCR detection is considered as a rapid and sensitive method for detection of PBV.
    [Show full text]
  • First Insight Into the Viral Community of the Cnidarian Model Metaorganism Aiptasia Using RNA-Seq Data
    First insight into the viral community of the cnidarian model metaorganism Aiptasia using RNA-Seq data Jan D. Brüwer and Christian R. Voolstra Red Sea Research Center, Division of Biological and Environmental Science and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Makkah, Saudi Arabia ABSTRACT Current research posits that all multicellular organisms live in symbioses with asso- ciated microorganisms and form so-called metaorganisms or holobionts. Cnidarian metaorganisms are of specific interest given that stony corals provide the foundation of the globally threatened coral reef ecosystems. To gain first insight into viruses associated with the coral model system Aiptasia (sensu Exaiptasia pallida), we analyzed an existing RNA-Seq dataset of aposymbiotic, partially populated, and fully symbiotic Aiptasia CC7 anemones with Symbiodinium. Our approach included the selective removal of anemone host and algal endosymbiont sequences and subsequent microbial sequence annotation. Of a total of 297 million raw sequence reads, 8.6 million (∼3%) remained after host and endosymbiont sequence removal. Of these, 3,293 sequences could be assigned as of viral origin. Taxonomic annotation of these sequences suggests that Aiptasia is associated with a diverse viral community, comprising 116 viral taxa covering 40 families. The viral assemblage was dominated by viruses from the families Herpesviridae (12.00%), Partitiviridae (9.93%), and Picornaviridae (9.87%). Despite an overall stable viral assemblage, we found that some viral taxa exhibited significant changes in their relative abundance when Aiptasia engaged in a symbiotic relationship with Symbiodinium. Elucidation of viral taxa consistently present across all conditions revealed a core virome of 15 viral taxa from 11 viral families, encompassing many viruses previously reported as members of coral viromes.
    [Show full text]
  • Supporting Information
    Supporting Information Rosenberg et al. 10.1073/pnas.1307243110 SI Results and Discussion domestic ungulates (horses, cows, sheep, goats, camels, and pigs) Of the 83 arboviruses, nonhuman vertebrate hosts have been and rodents in both groups might be a consequence of spatial identified for 70 (84%); the remaining 13 are presumed to be proximity to humans. Sentinel monkeys were often used in pro- zoonoses because there is no indication they can be transmitted cedures to isolate arboviruses, which might account for their directly between humans by vectors (Table S1). Animal hosts have higher representation among arboviruses. In contrast, there are been identified for at least 57 (44%) of the 130 nonarboviruses; an few published records of bats being routinely sampled during additional 5 (8%) are presumed on epidemiological evidence to arbovirus studies, and only two arboviruses (3%) have been iso- have nonhuman reservoirs (Table S1). A number of viruses infect lated from bats. The reason a much larger number of arbovirus more than one nonhuman vertebrate host species and it is likely species (n = 16) have been isolated from birds than have that the variety of hosts is wider than has been recorded. The nonarbovirus species (n = 1) might, however, be characteristic of predominant host groups for arboviruses (n = 70) are nonhuman the pathogenicity of the togaviruses and flaviviruses, which are primates (31%), rodents (29%), ungulates (26%), and birds (23%); much more common among the arboviruses. The most prominent for the nonarboviruses (n = 57), they are rodents (30%), ungu- vectors of arboviruses were mosquitoes (67%), ticks (19%), and lates (26%), bats (23%), and primates (16%).
    [Show full text]
  • Molecular Detection of Human Enteric Viruses Circulating
    Alcalá et al. Gut Pathog (2018) 10:6 https://doi.org/10.1186/s13099-018-0232-2 Gut Pathogens RESEARCH Open Access Molecular detection of human enteric viruses circulating among children with acute gastroenteritis in Valencia, Venezuela, before rotavirus vaccine implementation Ana C. Alcalá1,4, Kriss Pérez1, Ruth Blanco1, Rosabel González3, Juan E. Ludert2, Ferdinando Liprandi1 and Esmeralda Vizzi1* Abstract Background: The role of rotavirus as main etiologic agent of diarrhea has been well documented worldwide, includ- ing in Venezuela. However, information about the prevalence of gastrointestinal viruses such as calicivirus, adenovirus and astrovirus is limited and the contribution of other agents as Aichi virus and klassevirus is largely unknown. To explore the etiological spectrum of diarrhea associated with agents other than rotaviruses, 227 stool samples from children under 5 years old with acute gastroenteritis, collected in Valencia (Venezuela) from 2001 to 2005, and previ- ously tested as rotavirus-negative, were analyzed for caliciviruses, adenoviruses, astroviruses, Aichi viruses, klassevi- ruses, picobirnaviruses and enteroviruses by specifc RT-PCRs. Results: At least one viral agent was detected in 134 (59%) of the samples analyzed, mainly from children under 24 months of age and most of them belonging to the lowest socioeconomic status. Overall, enterovirus was identi- fed as the most common viral agent (37.9%), followed by calicivirus (23.3%), adenovirus (11.5%), astrovirus (3.5%), klassevirus (1.3%) and Aichi virus (0.4%), while no picobirnavirus was detected. Klasseviruses were found during 2004 and 2005 and Aichi viruses only in 2005, indicating their circulation in Venezuela; meanwhile, the rest of the viruses were detected during the whole study period.
    [Show full text]
  • Infectious Diseases of Rwanda
    INFECTIOUS DISEASES OF RWANDA Stephen Berger, MD 2015 Edition Infectious Diseases of Rwanda - 2015 edition Copyright Infectious Diseases of Rwanda - 2015 edition Stephen Berger, MD Copyright © 2015 by GIDEON Informatics, Inc. All rights reserved. Published by GIDEON Informatics, Inc, Los Angeles, California, USA. www.gideononline.com Cover design by GIDEON Informatics, Inc No part of this book may be reproduced or transmitted in any form or by any means without written permission from the publisher. Contact GIDEON Informatics at [email protected]. ISBN: 978-1-4988-0605-3 Visit http://www.gideononline.com/ebooks/ for the up to date list of GIDEON ebooks. DISCLAIMER Publisher assumes no liability to patients with respect to the actions of physicians, health care facilities and other users, and is not responsible for any injury, death or damage resulting from the use, misuse or interpretation of information obtained through this book. Therapeutic options listed are limited to published studies and reviews. Therapy should not be undertaken without a thorough assessment of the indications, contraindications and side effects of any prospective drug or intervention. Furthermore, the data for the book are largely derived from incidence and prevalence statistics whose accuracy will vary widely for individual diseases and countries. Changes in endemicity, incidence, and drugs of choice may occur. The list of drugs, infectious diseases and even country names will vary with time. Scope of Content Disease designations may reflect a specific pathogen (ie, Adenovirus infection), generic pathology (Pneumonia - bacterial) or etiologic grouping (Coltiviruses - Old world). Such classification reflects the clinical approach to disease allocation in the Infectious Diseases Module of the GIDEON web application.
    [Show full text]
  • Libro De Abstract
    SPECIAL THANKS EMPRESAS COLABORADORAS SEV VI R O L O G Í A Publicación Oficial de la Sociedad Española de Virología 13th Spanish National Congress Of Virology Madrid 2015 CONGRESO NACIONAL DE Volumen 18 Número 1/2015 EXTRAORDINARIO VIROLOGÍA . PUBLICACIÓN OFICIAL DE LA SOCIEDAD ESPAÑOLA DE VIROLOGÍA 13th Spanish National Congress Of Virology Madrid 2015 Del 7 al 10 de junio de 2015 Auditorio de la Fábrica Nacional de Moneda y Timbre Real Casa de la Moneda de Madrid Volumen 18 Madrid 2015 Número 1/2015 EXTRAORDINARIO Edición y Coordinación: M Angeles Muñoz-Fernández &M. Dolores García-Alonso Diseño y Maquetación: DM&VCH.events.S.L. Diseño Portada: M. Dolores García-Alonso Impresión: Fragma: Servicios de impresión digital en Madrid ISSN (versión digital): 2172-6523 SEV – Sociedad Española de Virología Centro de Biología Molecular “Severo Ochoa” C/ Nicolás Cabrera, 1 28049 Cantoblanco – Madrid [email protected] Página web del congreso: www.congresonacionalvirologia2015.com La responsabilidad del contenido de las colaboraciones publicadas corresponderá a sus autores, quienes autorizan la reproducción de sus artículos a la SEV exclusivamente para esta edición. La SEV no hace necesariamente suyas las opiniones o los criterios expresados por sus colaboradores. Virología. Publicación Oficial de la Sociedad Española de Virología XIII CONGRESO NACIONAL DE VIROLOGÍA B I E N V E N I D A El Comité Organizador del XIII Congreso Nacional de Virología (XIII CNV) tiene el placer de comunicaros que éste se celebrará en Madrid, del 7 al 10 de junio de 2015. En el XIII CNV participan conjuntamente la Sociedad Española de Virología (SEV) y la Sociedad Italiana de Virología (SIV), y estará abierto13th a Spanish la participación National de virólogos de Latinoamérica.
    [Show full text]
  • Formation and Working Mechanism of the Picornavirus Vpg Uridylylation
    Available online at www.sciencedirect.com ScienceDirect Formation and working mechanism of the picornavirus VPg uridylylation complex 1,2,6 3,6 2,4,5 Yuna Sun , Yu Guo and Zhiyong Lou The initiation of picornavirus replication is featured by the initiated by a protein primer is the most unique one, in uridylylation of viral protein genome-linked (VPg). In this which the virus encodes a protein, that is, viral protein process, viral RNA-dependent RNA polymerase (RdRp) genome-linked (VPg), that acts as the primer to initiate catalyzes two uridine monophosphate (UMP) molecules to the replication. hydroxyl group of the third tyrosine residue of VPg. 0 Subsequently, the uridylylated VPg (VPg-pUpU) functions as VPg was first discovered to be covalently linked to the 5 the protein primer to initiate the replication of the viral genome. end of viral genomes extracted from mature virions of Although a large body of functional and structural works has several single-stranded positive-sense RNA (+ssRNA) been performed to define individual snapshots for particular viruses and subsequently was demonstrated to be stages of the VPg uridylylation process, the formation, encoded by the viral genome [1 ,2]. So far, VPg has only dynamics and mechanism of the whole VPg uridylylation been experimentally demonstrated in the Picornaviridae complex still requires further elucidation. We would like to [3 ,4,5] and Caliciviridae [2] families, and its existence provide an overview of the current knowledge of the been computationally predicted in Astroviridae [6,7
    [Show full text]
  • Wastewater Surveillance for Infectious Disease: a Systematic Review
    medRxiv preprint doi: https://doi.org/10.1101/2021.07.26.21261155; this version posted July 29, 2021. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license . Title: Wastewater surveillance for infectious disease: a systematic review Authors: Pruthvi Kilaru MPH1, Dustin Hill PhD1,2, Kathryn Anderson MD/PhD3, Mary B. Collins PhD4, Hyatt Green PhD5, Brittany L. Kmush PhD1, David A. Larsen PhD*1 1. Department of Public Health, Syracuse University, Syracuse, NY, USA 2. Graduate Program in Environmental Science, SUNY ESF, Syracuse, NY, USA 3. Department of Medicine, SUNY Upstate, Syracuse, NY, USA 4. Department of Environmental Studies, SUNY ESF, Syracuse, NY, USA 5. Department of Environmental Biology, SUNY ESF, Syracuse, NY, USA * Correspondence to: Dr. David Larsen, Department of Public Health, Syracuse University, Syracuse, NY, 13244, USA Abstract: Wastewater surveillance of SARS-CoV-2 has shown to be a valuable source of information regarding SARS-CoV-2 transmission and COVID-19 cases. Though the method has been used for several decades to track other infectious diseases, there has not been a comprehensive review outlining all of the pathogens surveilled through wastewater. The aim of this study is to identify what infectious diseases have been previously studied via wastewater surveillance prior to the COVID-19 Pandemic and identify common characteristics between the studies, as well as identify current gaps in knowledge. Peer-reviewed articles published as of August 1, 2020 that examined wastewater for communicable and infectious human pathogens on 2 or more occasions were included in the study.
    [Show full text]
  • Nuclear Proteins Hijacked by Mammalian Cytoplasmic Plus Strand RNA Viruses
    View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by Elsevier - Publisher Connector Virology 479-480 (2015) 457–474 Contents lists available at ScienceDirect Virology journal homepage: www.elsevier.com/locate/yviro Review Nuclear proteins hijacked by mammalian cytoplasmic plus strand RNA viruses Richard E. Lloyd n Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, United States article info abstract Article history: Plus strand RNA viruses that replicate in the cytoplasm face challenges in supporting the numerous Received 8 December 2014 biosynthetic functions required for replication and propagation. Most of these viruses are genetically Returned to author for revisions simple and rely heavily on co-opting cellular proteins, particularly cellular RNA-binding proteins, into 12 January 2015 new roles for support of virus infection at the level of virus-specific translation, and building RNA Accepted 3 March 2015 replication complexes. In the course of infectious cycles many nuclear-cytoplasmic shuttling proteins of Available online 26 March 2015 mostly nuclear distribution are detained in the cytoplasm by viruses and re-purposed for their own gain. Keywords: Many mammalian viruses hijack a common group of the same factors. This review summarizes recent RNA virus gains in our knowledge of how cytoplasmic RNA viruses use these co-opted host nuclear factors in new Enterovirus functional roles supporting virus translation and virus RNA replication and common themes employed Poliovirus between different virus groups. Flavivirus & Norovirus 2015 Elsevier Inc. All rights reserved. Hepatitis C virus Coronavirus PTB PCBP2 La protein UNR SRp20 hnRNP C hnRNP A1 hnRNP K hnRNP M RNA helicase A NSAP Tia1/TIAR G3BP1 Contents Introduction.
    [Show full text]