DOCSLIB.ORG

Calcium Gluconate Injection Contains 95 Mg/Ml Calcium Gluconate Monohydrate and 3.0 Mg/Ml Calcium Saccharate

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Calcium Gluconate Injection Contains 95 Mg/Ml Calcium Gluconate Monohydrate and 3.0 Mg/Ml Calcium Saccharate Calcium Gluconate Injection Contains 95 mg/mL Calcium Gluconate Monohydrate and 3.0 mg/mL Calcium Saccharate Consumer Medicine Information What is in this leaflet Before you are given You should not be given Calcium Gluconate Injection if you have been Calcium Gluconate bed ridden for a long time causing This leaflet answers some common the loss of calcium from the bones. questions about Calcium Gluconate Injection Injection. It does not contain all the You should not be given Calcium available information. It does not take Gluconate Injection if you are being the place of talking to your doctor. When you must not be given treated with certain heart drugs such it as digoxin and digitalis. All medicines have risks and benefits. Your doctor has weighed the risks of You should not be given Calcium You should not be given Calcium you being given Calcium Gluconate Gluconate Injection if you have an Gluconate Injection if the solution is Injection against the benefits they allergy to: discoloured, cloudy, turbid, or a expect it will have for you. • any medicine containing calcium precipitate is present. The solution is gluconate normally a clear, colourless liquid. If you have any concerns about being given this medicine, ask your • any of the ingredients listed at the You should not be given Calcium doctor. end of this leaflet. Gluconate Injection if when diluted with another solution it causes the Some of the symptoms of an allergic Keep this leaflet. solution to precipitate, become You may need to read it again. reaction may include: cloudy, turbid, discolour, or particles • shortness of breath are visible. • wheezing or difficulty breathing The doctor or nurse will check to ensure the medicine is not past its • What Calcium swelling of the face, lips, tongue expiry date and has not been tampered or other parts of the body Gluconate Injection is with. • rash, itching or hives on the skin. used for If you are not sure whether you You should not be given Calcium should be given this medicine, talk to Calcium gluconate is a calcium salt Gluconate Injection if the calcium your doctor. used to treat or prevent a lack of levels in your blood or urine are calcium in the body. Other reasons for above normal levels. Some conditions Before you are given it treatment with Calcium Gluconate that may cause high levels of calcium Injection are: are: Tell your doctor if you have allergies to any other medicines, foods, • high potassium levels in the blood • hyperparathyroidism, an over preservatives or dyes. • an overdose of magnesium sulfate production of certain hormones Tell your doctor if you have or have i.e. Epsom salts • an overdose of vitamin D had any of the following medical • sudden severe stomach pain • tumours of the bone or other conditions: • during heart resuscitation to tumours which raise levels of • kidney or heart disease strengthen the heart muscle. calcium in the blood. • kidney stones or stones of the This medicine works by increasing the You should not be given Calcium urinary tract level of calcium in the blood or by Gluconate Injection if you have binding to excess potassium or severe heart disease. • diseases causing high levels of magnesium in the blood. vitamin D in the blood You should not be given Calcium Ask your doctor if you have any Gluconate Injection if you have • dehydration or any other chemical questions about why this medicine severe kidney disease. imbalance in the blood has been prescribed for you. You should not be given Calcium • high phosphate levels in the blood Your doctor may have prescribed it for Gluconate Injection if you suffer • another reason. from galactosaemia. This is a rare a blood transfusion. genetic disorder. Calcium Gluconate Injection Page 1 of 3 Version 05 Tell your doctor if you are pregnant, planning to become pregnant or are How Calcium While you are being breast-feeding. Your doctor will Gluconate Injection is given Calcium discuss the risks and benefits of you given Gluconate Injection being given Calcium Gluconate Injection during pregnancy and breast- Calcium Gluconate Injection must feeding. only be given by a doctor or nurse. Things you must do If you have not told your doctor How it is given If you are about to be started on any about any of the above, tell him/her new medicine, remind your doctor before you are given Calcium It is usually given as a slow injection and pharmacist that you have been Gluconate Injection. given Calcium Gluconate Injection. or infusion into a vein. Tell any other doctors, dentists, and Taking other medicines Calcium Gluconate Injection will pharmacists who treat you that you normally be warmed to body Tell your doctor if you are taking have been given this medicine. temperature before use. any other medicines, including If you are going to have surgery, tell medicines that you buy without a the surgeon or anaesthetist that you prescription from your pharmacy, How much is given have been given this medicine. supermarket, health food shop, Your doctor will decide what dose of It may affect other medicines used naturopath or herbalist. calcium gluconate you will receive and during surgery. Some medicines and calcium gluconate for how long you will receive it. This may interfere with each other. These depends on your medical condition and If you become pregnant while being include: other factors, such as your weight. given this medicine, tell your doctor • medicines used to treat heart Sometimes only a single dose of immediately. disease such as cardiac glycosides calcium gluconate is required. If you are about to have any blood eg digoxin or digitalis tests, tell your doctor that you have • tetracycline antibiotics such as If you are given too much been given this medicine. Achromycin and Tetrex (overdose) It may interfere with the results of some tests. • high doses of vitamin D or vitamin Calcium Gluconate Injection must A only be given by a doctor or nurse so Keep all of your doctor’s an overdose is unlikely to occur. appointments so that your progress • medicines used to treat Paget’s can be checked. disease such as calcitonin Some medical conditions may result in Your doctor may do some tests from • medicines used to reduce blood too much calcium in the blood. Your time to time to make sure the medicine pressure such as verapamil and doctor or nurse will monitor the level is working and to prevent unwanted other calcium channel blockers of calcium in the blood. side effects. • medicines used to reduce excess If you notice any symptoms of an Things to be careful of fluid in the body such as thiazide overdose contact your doctor diuretics immediately or go to the Emergency Be careful driving or operating • medicines used to relax muscles Department at the nearest hospital. prior to surgery such as machinery until you know how tubocurarine Symptoms of an overdose may include: Calcium Gluconate Injection affects you. This medicine may cause • nausea, vomiting • medicines containing calcium, dizziness, light-headedness or magnesium, potassium phosphate • loss of appetite weakness in some people. If you have or sodium phosphate. any of these symptoms, do not drive, • abdominal pain, constipation These medicines may be affected by operate machinery or do anything else Calcium Gluconate Injection or may • weakness in the muscles and dangerous. affect how well it works. You may painful joints need different amounts of your If you feel light-headed, dizzy or • medicines, or you may need to take excessive thirst and excessive faint when getting out of bed or different medicines. passing of urine standing up, get up slowly. Standing up slowly, especially when Your doctor or pharmacist have more • change in heart beat or chest pain. you get up from bed or chairs, will help information on medicines to be careful For information on the management your body get used to the change in with or avoid while being given of overdose, contact the Poisons position and blood pressure. If this Calcium Gluconate Injection. Information Centre on 13 11 26 problem continues or gets worse, talk (Australia). to your doctor. Calcium Gluconate Injection Page 2 of 3 Version 05 Side effects After being given Manufacturer Calcium Gluconate Calcium Gluconate Injection is made Tell your doctor or nurse as soon as in Australia by: Injection possible if you do not feel well while Phebra Pty Ltd you are being given Calcium 19 Orion Road After you have been given Calcium Gluconate Injection. Lane Cove West NSW 2066 This medicine may have unwanted side Gluconate Injection you should lie Australia down for a short time to prevent effects in a few people. All medicines dizziness. can have side effects. Sometimes they Calcium Gluconate Injection 2.2 mmol are serious, most of the time they are If you feel light-headed or dizzy of calcium in 10 mL vial. not. You may need medical treatment when getting up, get up slowly. AUST R 22923 if you get some of the side effects. Standing up slowly will help your body Phebra product code- INJ022 get used to the change in position and Do not be alarmed by this list of blood pressure. possible side effects. You may not This leaflet was prepared in Mar 2020. If this problem continues or gets experience any of them. worse, talk to your doctor or nurse. Ask your doctor to answer any questions you may have. Phebra and the Phi symbol are trademarks Storage of Phebra Pty Ltd. Tell your doctor or nurse if you notice any of the following and they Calcium Gluconate Injection will be worry you: stored in the surgery, pharmacy or • tingling sensation ward of a hospital.
Load more

Recommended publications
  • Management of Poisoning
    MOH CLINICAL PRACTICE GUIDELINES December/2011 Management of Poisoning Health Ministry of Sciences Chapter of Emergency College of College of Family Manpower Authority Physicians Physicians, Physicians Academy of Medicine, Singapore Singapore Singapore Singapore Medical Pharmaceutical Society Society for Emergency Toxicology Singapore Paediatric Association of Singapore Medicine in Singapore Society (Singapore) Society Executive summary of recommendations Details of recommendations can be found in the main text at the pages indicated. Principles of management of acute poisoning – resuscitating the poisoned patient GPP In a critically poisoned patient, measures beyond standard resuscitative protocol like those listed above need to be implemented and a specialist experienced in poisoning management should be consulted (pg 55). GPP D Prolonged resuscitation should be attempted in drug-induced cardiac arrest (pg 55). Grade D, Level 3 1 C Titrated doses of naloxone, together with bag-valve-mask ventilation, should be administered for suspected opioid-induced coma, prior to intubation for respiratory insuffi ciency (pg 56). Grade C, Level 2+ D In bradycardia due to calcium channel or beta-blocker toxicity that is refractory to conventional vasopressor therapy, intravenous calcium, glucagon or insulin should be used (pg 57). Grade D, Level 3 B Patients with actual or potential life threatening cardiac arrhythmia, hyperkalaemia or rapidly progressive toxicity from digoxin poisoning should be treated with digoxin-specifi c antibodies (pg 57). Grade B, Level 2++ B Titrated doses of benzodiazepine should be given in hyperadrenergic- induced tachycardia states resulting from poisoning (pg 57). Grade B, Level 1+ D Non-selective beta-blockers, like propranolol, should be avoided in stimulant toxicity as unopposed alpha agonism may worsen accompanying hypertension (pg 57).
    [Show full text]
  • GHS Calcium Lactate Gluconate MSDS.Pdf
    Safety Data Sheet (Calcium Lactate Gluconate) DATE PREPARED: 7/9/2015 Section 1. Product and Company Identification Product Name Calcium Lactate Gluconate CAS Number 11116-97-5 Parchem - fine & specialty chemicals EMERGENCY RESPONSE NUMBER 415 Huguenot Street CHEMTEL New Rochelle, NY 10801 Toll Free US & Canada: 1 (800) 255-3924 (914) 654-6800 (914) 654-6899 All other Origins: 1 (813) 248-0585 parchem.com [email protected] Collect Calls Accepted Section 2. Hazards Identification Classification of the substance or mixture Classification according to Directive 67/548/EEC or 1999/45/EC as amended: This preparation does not meet the criteria for classification according to Directive 1999/45/EC as amended. Classification according to Regulation (EC) No 1272/2008 as amended: This mixture does not meet the criteria for classification according to Regulation (EC) 1272/2008 as amended. Hazard and precautionary statements Hazard statements: The substance does not meet the criteria for classification. Precautionary statements: Not available. Appearance & Odor: White powder with no odor. Fire & Explosion Hazards Potential for dust explosion may exist. This product is not defined as flammable or combustible. However, the product may decompose under fire conditions to produce toxic oxides of carbon. Depending upon conditions, dusts may be sensitive to static discharge. Avoid possibility of dry powder and friction causing static electricity in presence of flammables (See NFPA-77, Chpt. 6) Primary Route of Exposure: Skin and eye contact are the primary routes of exposure to this product. Inhalation Acute Exposure: Inhalation of dust may cause mild irritation. Skin Contact - Acute: Skin contact is not expected to cause irritation.
    [Show full text]
  • Wednesday May 26, 1999
    5±26±99 Vol. 64 No. 101 Wednesday Pages 28333±28712 May 26, 1999 federal register 1 VerDate 06-MAY-99 21:29 May 25, 1999 Jkt 183247 PO 00000 Frm 00001 Fmt 4710 Sfmt 4710 E:\FR\FM\26MYWS.XXX pfrm03 PsN: 26MYWS II Federal Register / Vol. 64, No. 101 / Wednesday, May 26, 1999 The FEDERAL REGISTER is published daily, Monday through SUBSCRIPTIONS AND COPIES Friday, except official holidays, by the Office of the Federal Register, National Archives and Records Administration, PUBLIC Washington, DC 20408, under the Federal Register Act (44 U.S.C. Subscriptions: Ch. 15) and the regulations of the Administrative Committee of Paper or fiche 202±512±1800 the Federal Register (1 CFR Ch. I). The Superintendent of Assistance with public subscriptions 512±1806 Documents, U.S. Government Printing Office, Washington, DC 20402 is the exclusive distributor of the official edition. General online information 202±512±1530; 1±888±293±6498 Single copies/back copies: The Federal Register provides a uniform system for making available to the public regulations and legal notices issued by Paper or fiche 512±1800 Federal agencies. These include Presidential proclamations and Assistance with public single copies 512±1803 Executive Orders, Federal agency documents having general FEDERAL AGENCIES applicability and legal effect, documents required to be published Subscriptions: by act of Congress, and other Federal agency documents of public Paper or fiche 523±5243 interest. Assistance with Federal agency subscriptions 523±5243 Documents are on file for public inspection in the Office of the Federal Register the day before they are published, unless the issuing agency requests earlier filing.
    [Show full text]
  • Calcium Gluconate
    CALCIUM GLUCONATE CLASSIFICATION Minerals and electrolytes TRADE NAME(S) Calcium Gluconate 10% (for IV use) Calcium Gluconate gel 2.5% (for topical use) DESIRED EFFECTS Lower potassium levels; pain relief and neutralizing fluoride ion MECHANISM OF ACTION Calcium is the primary component of skeletal tissue. Bone serves as a calcium depot and as a reservoir for electrolytes and buffers. INDICATIONS Suspected hyperkalemia in adult PEA/Asystole Antidote for calcium channel blocker overdose and magnesium sulfate toxicity Gel is used for hydrofluoric acid burns Suspected hyperkalemia with adult crush injury or peaked T-waves on EKG CONTRAINDICATIONS Should not be given to patients with digitalis toxicity Should be used with caution in patients with dehydration ADVERSE REACTIONS When given too rapidly or to someone on digitalis, can cause sudden death from ventricular fibrillation May cause mild to severe IV site irritation SPECIAL CONSIDERATIONS Must either use a different IV line or flush line with copious normal saline if being given with sodium bicarbonate. When used on hydroflouric acid burns, relief of pain is the only indication of treatment efficacy. Therefore, use of analgesic agents is not recommended. DOSING REGIMEN Suspected hyperkalemia in adult PEA/asystole or adult crush injury, or evidence of EKG changes (Ex. peaked T-waves) o Calcium gluconate 10% 15-30 ml IV/IO over 2-5 minutes KNOWN calcium channel blocker overdose - administer 3 grams IV/IO may repeat dose in 10 minutes if no effect. Hydrofluoric acid burns apply calcium gluconate gel 2.5% every 15 minutes to burned area and massage continuously until pain disappears.
    [Show full text]
  • Antidote Stocking Tier C
    These Tier C recommendations are general To Contact your Regional Poison Center: (800) 222-1222 Consultation is available by a Specialist in Poison Information or Toxicologist (upon request) 24 hours daily. Toxin Current Recommended Antidote Dosing Other Info Stock Stock Indicated for moderate to severe envenomations Moderate: Evidence of local tissue injury that extends 1 4-6 vials IV q2-4h Antivenin Snake bite major joint proximal to bite until pain improves, Crotalidae (Copperhead, and/or numeric coagulopathy 12 vials swelling stops, or Polyvalent Immune Water without clinical bleeding clinical bleeding FAB moccasins, resolves, then 2 vials (CroFab™) Rattlesnakes) Severe: Local injury >1 joint, q6h for 3 doses documented compartment syndrome, coagulopathy with clinical bleeding, hypotension, angioedema, and/or neurological findings None (currently must be drop-shipped based Antivenin-black Black Widow 1 vial in 50 ml of NS Equine derived antivenom on patient presentation widow envenomation – black widows not likely in western KY) Organo- 2-4 mg IV q5-10 phosphate or minutes or 0.02- carbamate Indicated for SLUDGE 5 x 20 ml (0.4 mg/ml) 0.08 mg/kg/hr IV Atropine pesticides symptoms associated with vials infusion until and cholinergic excess excessive bronchial muscarine secretions terminate mushrooms These Tier C recommendations are general To Contact your Regional Poison Center: (800) 222-1222 Consultation is available by a Specialist in Poison Information or Toxicologist (upon request) 24 hours daily. Antidote Current Recommended Toxin
    [Show full text]
  • Obstetric Safety
    Obstetric Safety DIAGNOSIS OF LABOUR FIRST STAGE . Latent phase . Cervix less than 4 cm dilated . Active phase . Cervix between 4 cm and 10 cm dilated SECOND STAGE . Early phase (non-expulsive) . Cervix fully dilated (10 cm) . Fetal descent continues . Patient has no urge to push . Late phase (expulsive) . Presenting part of fetus reaches the pelvic floor and the patient has the urge to push . Typically lasts less than 1 hour in primigravida women and less than 30 minutes in multigravida women Carry .out Dedicated vaginal examinations equipment at leastfor procedures once every 4 hours in the first stage of labour. andEquipment plot the findings to monitor on the patients, partograph. as required for the procedure . Drugs and other consumables for routine and emergency use The partograph is very helpful in monitoring the progress of labour and in the early detection of abnormal labour patterns. WHO/HPW/CPR 2004 reformatted 2012 1 DIAGNOSIS OF VAGINAL BLEEDING IN EARLY PREGNANCY Typical Symptoms and Probable Occasional Symptoms and Signs Signs Diagnosis . Light* bleeding . Cramping/lower abdominal pain Threatened . Closed cervix . Uterus softer than normal abortion . Uterus corresponds to dates . Light bleeding . Abdominal pain . Fainting . Closed cervix . Tender adnexal mass Ectopic . Uterus slightly larger than . Amenorrhea pregnancy normal . Cervical motion tenderness . Uterus softer than normal . Light bleeding . Light cramping/lower abdominal pain . Closed cervix Complete . History of expulsion of products of . Uterus smaller than dates abortion conception . Uterus softer than normal . Cramping/lower abdominal pain . Heavy** bleeding . Tender uterus Inevitable . Dilated cervix . No expulsion of products of abortion . Uterus corresponds to dates conception . Heavy bleeding .
    [Show full text]
  • The Regional Center for Poison Control and Prevention Serving Massachusetts and Rhode Island
    The Regional Center for Poison Control and Prevention Serving Massachusetts and Rhode Island Poison Potential Antidote Acetaminophen n-Acetylcysteine [Mucomyst®] Anticholinergics Physostigmine [Antilirium®] Benzodiazepines Flumazenil [Romazicon®] Beta-adrenergic blockers Glucagon Botulinum toxin Trivalent ABE botulinum antitoxin Calcium chloride or calcium gluconate Calcium channel blockers Hyperinsulinemia-euglycemia (HIE) therapy Atropine Carbamates Pralidoxime (2-PAM) [Protopam®] Carbon monoxide Oxygen; Hyperbaric oxygen (HBO) Clonidine Naloxone [Narcan®] Cyanide Cyanide Kit (Amyl/sodium nitrite, sodium thiosulfate) Digoxin (Cardiac glycosides) Digoxin Immune FAB Ovine [Digibind®, Digifab®] Epi Pen (Epinephrine SQ) Phentolamine [Regitine®] Ethanol Ethylene glycol 4-Methylpyrazole (Fomepizole) [Antizol®] Fluoride Calcium chloride or calcium gluconate Heparins Protamine Hydrofluoric acid Calcium chloride or calcium gluconate Hydrogen sulfide Oxygen; Hyperbaric oxygen (HBO); Sodium nitrite Iodine Starch Isoniazid Pyridoxine (Vitamin B6 ) METALS Dimercaprol [BAL] Arsenic Dimercaptosuccinic acid (DMSA, succimer) [Chemet®] Bismuth Dimercaprol [BAL] Copper D-Penicillamine [Cuprimine®] Gold Dimercaprol [BAL] Iron Deferoxamine [Desferal®] Dimercaprol [BAL] Edetate calcium disodium (Calcium EDTA) Lead Dimercaptosuccinic acid (DMSA, succimer) [Chemet®] D-Penicillamine [Cuprimine®] Dimercaprol [BAL] Mercury Dimercaptosuccinic acid (DMSA, succimer) [Chemet®] Ethanol Methanol 4-Methylpyrazole (Fomepizole) [Antizol®] Methemoglobinemic agents Methylene
    [Show full text]
  • Man with Syncope Emily Lai MD, PGY-2 and Anita Mehrotra MD, PGY-1
    Pulse: EKG Man with Syncope Emily Lai MD, PGY-2 and Anita Mehrotra MD, PGY-1 Mr. K, a 57 year-old Caucasian male with a history of atorvastatin, furosemide, aspirin and niacin. He had no coronary artery disease, dilated ischemic cardiomy- known drug allergies. Mr. K was a retired train opathy, ventricular fibrillation arrest status post conductor. He smoked half of a pack of cigarettes a day implantable cardioverter defibrillator (ICD) placement and had an 80 pack-year smoking history. He had a was admitted to telemetry for two syncopal episodes. The history of alcohol, cocaine, and amphetamine abuse, but patient described multiple episodes of dizziness with he quit these drugs 15 years prior. He denied any history fatigue over the week prior to admission, the last two of intravenous drug use. episodes resulting in loss of consciousness with bladder Physical examination on admission was significant for incontinence. He was home alone when these episodes elevated jugular venous pressure, a grade II/VI systolic occurred and was unsure of how long he had been ejection murmur over the left sternal border, diffuse unconscious. Mr. K was not aware of any recent firing of wheezes on lung exam, and 2+ lower extremity edema. his ICD. He denied any shortness of breath, chest pain, Laboratory results showed a B-type natriuretic peptide diaphoresis, recent fevers or chills. level of 662 pg/ml, a creatinine of 1.0 mg/dL, and a His medical history was significant for hypertension, digoxin level of 1.6 ng/mL. Chest X-ray showed coronary artery disease status post two vessel coronary moderate pulmonary edema.
    [Show full text]
  • LCCH Emergency Resuscitation Infusion Guide
    LCCH Emergency Resuscitation Infusion Guide Drug & Presentation Reconstitution & Final drug Dosage range Route & Administration Comments Dilution concentration Acetylcysteine inj See N-Acetylcysteine (NAC) adrenaline 1:1000 1mg in 50mL 0.02mg/mL 0.01 to 2 microg/kg/min IV infusion Central Line with 0.9% NaCl / 5% glucose Incompatible with Sodium Bicarbonate alPROStadil (PGE1) 100microg in 50mL 2microg/mL 0.01 to 400 nanog/kg/min IV infusion Stored in fridge (prostaglandin) with 0.9% NaCl (equals 2000 nanog/mL) May cause apnoea amINOPHYLLIne inj LOAD 250mg in 50mL 5mg/mL Asthma LOAD: IV infusion of exact dose Alkaline (ph 8.6-9) with 5% Glucose / 5 mg/kg over 30 to 60 mins 0.9% NaCl amINOPHYLLIne INFUS 250mg in 50mL 5mg/mL 0.5 to 1.5 mg/kg/hr IV infusion of exact dose Alkaline (ph 8.6-9) with 5% Glucose / Usually 10mg/kg over 30- over 60 mins NOTE: Usually initiated at PICU 0.9% NaCl 60mins discretion amIODARone CVL(<45kg) 300mg in 50mL 6mg/mL 5 to 15 microg/kg/min IV infusion Incompatible with sodium chloride with 5% glucose solutions amIODARone CVL(>45kg) 300mg in 50mL 6mg/mL 0.01 to 37 mg/hr IV infusion Monitor ECG and blood pressure with 5% glucose amIODARone PERIPH 100mg in 50mL 2mg/mL 5 to 15 microg/kg/min IV infusion Incompatible with sodium chloride (<45kg) with 5% glucose solutions Monitor ECG and blood pressure amIODARone PERIPH 900mg in 450ml 2mg/mL 0.01 to 37 mg/hr IV infusion (>45kg) with 5% glucose calcium CHLORide 6.8mmol in 10mL 0.68mmol/mL 0.01 to 0.61 mmol/kg/hr IV infusion Central Line only (CVL only) with 5% glucose / 0.9% NaCl LCCH Emergency Resuscitation Infusion Guide - 1 - Version 3, 22 March 2015.
    [Show full text]
  • 10D) Drugs (Dosage, Administration, Precautions and Monitoring
    INSTRUCTIONS FOR ONCOLOGY WARD (10D) DRUGS (DOSAGE, ADMINISTRATION, PRECAUTIONS AND MONITORING) PREPEARED BY CLINICAL PHARMACIST: ESHRAQ ALABWEENY THE SUPERVISOR OF DRUG INFORMATION CENTER / JUST 1 . Calcium Gluconate 10 % ( 10 ml) Dosage: Hypocalcemia: IV: Mild (ionized calcium: [1 to 1.2 mmol/L]): 1 to 2 g over 2 hours; asymptomatic patients may be given oral calcium. Moderate to severe (without seizure or tetany; ionized calcium: [<1 mmol/L]): 4 g over 4 hours. Severe symptomatic (eg, seizure, tetany): 1 to 2 g over 10 minutes; repeat every 60 minutes until symptoms resolve. Note: Repeat ionized calcium measurement 6 to 10 hours after completion of administration. Check for hypomagnesemia and correct if present. Consider continuous infusion if hypocalcemia is likely to recur due to ongoing losses. Continuous infusion: 5 to 20 mg/kg/hour; in patients with hypoparathyroidism, oral calcium and active vitamin D (ie, calcitriol) with or without ergocalciferol or cholecalciferol should be initiated as soon as is practical; IV calcium is generally tapered slowly while oral therapy is adjusted . Hypocalcemia induced by citrate-based replacement fluid during continuous renal replacement therapy (CRRT): IV (administered via return line): Note: Prior to initiation of CRRT, check ionized calcium and administer calcium gluconate if (<1 mmol/L) until (>1 mmol/L). During CRRT, a continuous infusion sliding scale may be initiated (may use calcium gluconate 20 gram/1,000 mL NS or D5W solution). The following schema has been employed : If ionized calcium is (<0.9 mmol/L): Notify nephrology. If ionized calcium is (0.9 to 1 mmol/L): 1.4 g/hour.
    [Show full text]
  • Clinical Review Hyperkalaemia
    For the full versions of these articles see bmj.com CLINICAL REVIEW Hyperkalaemia Moffat J Nyirenda,1 Justin I Tang,1 Paul L Padfield,2 Jonathan R Seckl1 1Endocrinology Unit, Centre for Hyperkalaemia is defined as serum potassium concen- SUMMARY POINTS Cardiovascular Science, Queen’s tration greater than 5.5 mmol/l. Its prevalence in the Medical Research Institute, Hyperkalaemia is usually caused by a combination of University of Edinburgh, Edinburgh general population is unknown, but it is thought to occur factors, but renal failure and drugs are often implicated 1 EH16 4TJ in 1-10% of patients admitted to hospital. The rate of Increased use of drugs that interact with the renin- 2Metabolic Unit, Western General morbidity and mortality associated with hyperkalaemia angiotensin-aldosterone system has caused the Hospital, Lothian University has risen greatly with the use of drugs that target the prevalence of hyperkalaemia to rise Hospitals NHS Trust, Edinburgh renin-angiotensin system, and since publication 10 years Correspondence to: M Nyirenda Hyperkalaemia can cause life threatening cardiac [email protected] ago of a randomised trial that showed that adding an arrhythmias and should be urgently managed aldosterone receptor antagonist to usual treatment for ECG changes correlate poorly with the degree of potassium Cite this as: BMJ 2009;339:b4114 congestive failure improved outcomes.2-5 disturbance doi: 10.1136/bmj.b4114 Potassium is the most abundant cation in the human body and has key roles in the excitatory properties range from 40 mmol to 200 mmol per day, potassium needed for conduction of nerve impulses and muscle levels in serum remain within the relatively narrow contraction.
    [Show full text]
  • Poison Control Antidote Poster
    Antidote Chart (The suggested minimum stocking level is a combination of factors; anticipation of the highest total dose of a drug generally given during a 24 hour period to a 70 kg adult.) General Decontamination Uses Dose Comments Activated Charcoal (without sorbitol) Most ingestions occurring within one hour Adults: 25–100 grams, Children: 1 g/kg May be given in multiple doses depending on ingestant to enhance elimination Activated Charcoal (with sorbitol) May be used as first AC given to patient if presents within Adults: 25–50 grams Should not be used for multiple dose activated charcoal regimens one hour of ingestion Children: Not generally recommended Whole Bowel Irrigation Drugs not bound by charcoal, sustained Adults: 500–2000 ml/hour Nasogastric tube should be used to maintain amount given (Polyethylene Glycol) release formulations, and body stuffers Children: 25 ml/kg/hour Syrup of Ipecac No longer recommended No longer recommended No longer recommended Poisoning Antidote Quantity to Stock* Comments Acetaminophen N-ACETYLYCYSTEINE 10–20% 600 ml (20% Mucomyst®) Because vomiting of the oral NAC is common, the facility should maintain a repeat dose (Mucomyst®) or 1200 ml (10% Mucomyst®) for each patient for initial dosing if continuation of treatment at facility is not anticipated. ACETADOTE® The IV Acetadote® was just approved in February 2004. Call the MAPCC for dosing, ACETYLCYSTEINE Injection for IV use 4 (30 ml) vials of 20% solution precautions and contraindications. Both the oral and IV forms of acetylcysteine should be administered within 8 hours for maximal protection against hepatic injury. Anticholinergic Poisoning PHYSOSTIGMINE (Antilirium®) 2–4 mg* Not generally recommended for children.
    [Show full text]