February 11, 2020 u vol. 117 u no. 6

From the Cover

3045 Cognitive evolution of paper wasps 2864 Climate change and wine grapes 3006 Locating illegal fishing vessels with albatrosses 3034 Origin of the frog urostyle 3281 Defense responses in flowering plants

Contents

THIS WEEK IN PNAS Cover image: Pictured is a female 2725 In This Issue northern paper wasp (Polistes fuscatus). Sara E. Miller et al. analyzed population genomic signatures of cognitive SCIENCE AND CULTURE—How science intersects with culture adaptation in P. fuscatus, which can 2728 Dinosaur art evolves with new discoveries in paleontology recognize the faces of individual wasps, Amy McDermott and found strong selection on loci related to brain development, learning, long-term memory, and visual QNAS processing. Each of these traits has evolved in conjunction with individual 2732 QnAs with Roger J. Davis recognition. The findings suggest that Sandeep Ravindran recognition of individual faces in P. See Inaugural Article on page 2751 fuscatus may be a recent evolutionary development. See the article by Miller COMMENTARIES et al. on pages 3045–3052. Image courtesy of Sara E. Miller. 2734 Reconceptualizing public engagement by land-grant university scientists Kathleen Hall Jamieson See companion article on page 1274 in issue 3 of volume 117 2737 Tool-using puffins prickle the puzzle of cognitive evolution Auguste M. P. von Bayern, Ivo Jacobs, and Mathias Osvath See companion article on page 1277 in issue 3 of volume 117 2740 Cystic fibrosis heterozygosity: Carrier state or haploinsufficiency? David Fisman See companion article on page 1621 in issue 3 of volume 117

LETTERS + 2743 Mechanisms for Ca2 -dependent permeability transition in mitochondria Paolo Bernardi 2745 Reply to Bernardi: The mitochondrial permeability transition pore and the ATP synthase John E. Walker, Joe Carroll, and Jiuya He 2747 Did giant and large dsDNA viruses originate before their eukaryotic hosts? Chuan Ku and Tsu-Wang Sun 2749 Reply to Ku and Sun: Ancestors of modern giant and large eukaryotic dsDNA viruses infected proto-eukaryotes Julien Guglielmini, Anthony C. Woo, Mart Krupovic, Patrick Forterre, and Morgan Gaia

Free online through the PNAS open access option. PNAS u February 11, 2020 u vol. 117 u no. 6 u iii–vii Downloaded by guest on September 25, 2021 INAUGURAL ARTICLE EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES 2824 Influence of Arctic sea-ice variability on Pacific 2751 Regulation of adipose tissue inflammation by trade winds interleukin 6 Charles F. Kennel and Elena Yulaeva Myoung Sook Han, Alexis White, Rachel J. Perry, Joao-Paulo Camporez, Juan Hidalgo, Gerald I. Shulman, ENGINEERING and Roger J. Davis 2835 Wireless, battery-free subdermally implantable See QnAs on page 2732 photometry systems for chronic recording of neural dynamics BRIEF REPORTS Alex Burton, Sofian N. Obaid, Abraham Va´zquez-Guardado, Matthew B. Schmit, Tucker Stuart, Le Cai, Zhiyuan Chen, 2761 How social network sites and other online Irawati Kandela, Chad R. Haney, Emily A. Waters, Haijiang Cai, intermediaries increase exposure to news John A. Rogers, Luyao Lu, and Philipp Gutruf Michael Scharkow, Frank Mangold, Sebastian Stier, and Johannes Breuer ENVIRONMENTAL SCIENCES 2764 Microtubules regulate cardiomyocyte transversal 2987 Declines in an abundant aquatic insect, the burrowing ’ Young s modulus mayfly, across major North American waterways Pamela Swiatlowska, Jose L. Sanchez-Alonso, Peter T. Wright, Phillip M. Stepanian, Sally A. Entrekin, Charlotte E. Pavel Novak, and Julia Gorelik Wainwright, Djordje Mirkovic, Jennifer L. Tank, 2767 High-complexity extracellular barcoding using and Jeffrey F. Kelly a viral hemagglutinin Gavriel Mullokandov, Gayathri Vijayakumar, Paul Leon, Carole PHYSICS Henry, Patrick C. Wilson, Florian Krammer, Peter Palese, 2846 The Nernst effect in Corbino geometry and Brian D. Brown A. V. Kavokin, B. L. Altshuler, S. G. Sharapov, P. S. Grigoryev, and A. A. Varlamov

PHYSICAL SCIENCES 2852 Theory of the strange metal Sr3Ru2O7 Connie H. Mousatov, Erez Berg, and Sean A. Hartnoll APPLIED PHYSICAL SCIENCES 2770 Organelle-specific targeting of polymersomes into SOCIAL SCIENCES the cell nucleus Christina Zelmer, Ludovit P. Zweifel, Larisa E. Kapinos, Ioana ANTHROPOLOGY Craciun, Zekiye P. Gu¨ven, Cornelia G. Palivan, and Roderick Y. H. Lim 2879 Archaeological evidence for two separate dispersals of Neanderthals into southern Siberia 2779 Observation of an apparent first-order glass transition – – Kseniya A. Kolobova, Richard G. Roberts, Victor P. Chabai, in ultrafragile Pt Cu P bulk metallic glasses Zenobia Jacobs, Maciej T. Krajcarz, Alena V. Shalagina, Jong H. Na, Sydney L. Corona, Andrew Hoff, Andrey I. Krivoshapkin, Bo Li, Thorsten Uthmeier, Sergey V. and William L. Johnson Markin, Mike W. Morley, Kieran O’Gorman, Natalia A. Rudaya, 2788 Fast-freezing kinetics inside a droplet impacting on Sahra Talamo, Bence Viola, and Anatoly P. Derevianko a cold surface Pallav Kant, Robin B. J. Koldeweij, Kirsten Harth, Michiel A. J. PSYCHOLOGICAL AND COGNITIVE SCIENCES van Limbeek, and Detlef Lohse 2993 Reciprocity and behavioral heterogeneity govern the stability of social networks Roslyn Dakin and T. Brandt Ryder BIOPHYSICS AND COMPUTATIONAL BIOLOGY 3192 GABA-mediated tonic inhibition differentially 3203 Transformation of speech sequences in human modulates gain in functional subtypes of sensorimotor circuits cortical interneurons Kathrin Mu¨sch, Kevin Himberger, Kean Ming Tan, Taufik A. Valiante, and Christopher J. Honey Alexander Bryson, Robert John Hatch, Bas-Jan Zandt, Christian Rossert, Samuel F. Berkovic, Christopher A. Reid, David B. 3291 Uncertainty in learning, choice, and visual fixation Grayden, Sean L. Hill, and Steven Petrou Hrvoje Stojic, Jacob L. Orquin, Peter Dayan, Raymond J. Dolan, and Maarten Speekenbrink CHEMISTRY 2795 Selectivity filter modalities and rapid inactivation of SOCIAL SCIENCES the hERG1 channel 2858 Market integration accounts for local variation in Williams E. Miranda, Kevin R. DeMarco, Jiqing Guo, generalized altruism in a nationwide Henry J. Duff, Igor Vorobyov, Colleen E. Clancy, lost-letter experiment and Sergei Yu. Noskov Delia Baldassarri 2805 Sum frequency generation, calculation of absolute intensities, comparison with experiments, and BIOLOGICAL SCIENCES two-field relaxation-based derivation Kai Niu and Rudolph A. Marcus AGRICULTURAL SCIENCES 2815 Designing a hybrid electrode toward high 2864 Diversity buffers winegrowing regions from climate + − energy density with a staged Li and PF6 change losses deintercalation/intercalation mechanism Ignacio Morales-Castilla, In˜aki Garcı´a de Corta´zar-Atauri, Junnan Hao, Fuhua Yang, Shilin Zhang, Hanna He, Guanglin Benjamin I. Cook, Thierry Lacombe, Amber Parker, Xia, Yajie Liu, Christophe Didier, Tongchao Liu, Wei Kong Cornelis van Leeuwen, Kimberly A. Nicholas, Pang, Vanessa K. Peterson, Jun Lu, and Zaiping Guo and Elizabeth M. Wolkovich

iv u www.pnas.org Contents Downloaded by guest on September 25, 2021 2870 Landscape context affects the sustainability of 2948 Structural analysis of the intrinsically disordered organic farming systems splicing factor Spp2 and its binding to the Olivia M. Smith, Abigail L. Cohen, John P. Reganold, DEAH-box ATPase Prp2 Matthew S. Jones, Robert J. Orpet, Joseph M. Florian Hamann, Andreas Schmitt, Filippo Favretto, Romina Taylor, Jessa H. Thurman, Kevin A. Cornell, Rachel L. Hofele, Piotr Neumann, ShengQi Xiang, Henning Urlaub, Olsson,YangGe,ChristinaM.Kennedy, Markus Zweckstetter, and Ralf Ficner and David W. Crowder

CELL BIOLOGY ANTHROPOLOGY 2957 Structural instability and divergence from conserved 2879 Archaeological evidence for two separate dispersals residues underlie intracellular retention of of Neanderthals into southern Siberia mammalian odorant receptors Kseniya A. Kolobova, Richard G. Roberts, Victor P. Chabai, Kentaro Ikegami, Claire A. de March, Maira H. Nagai, Zenobia Jacobs, Maciej T. Krajcarz, Alena V. Shalagina, Soumadwip Ghosh, Matthew Do, Ruchira Sharma, Elise S. Andrey I. Krivoshapkin, Bo Li, Thorsten Uthmeier, Sergey V. Bruguera, Yueyang Eric Lu, Yosuke Fukutani, Nagarajan Markin, Mike W. Morley, Kieran O’Gorman, Natalia A. Rudaya, Vaidehi, Masafumi Yohda, and Hiroaki Matsunami Sahra Talamo, Bence Viola, and Anatoly P. Derevianko 2968 Tetraspanins TSP-12 and TSP-14 function redundantly to regulate the trafficking of the type II BMP APPLIED BIOLOGICAL SCIENCES receptor in Caenorhabditis elegans 2770 Organelle-specific targeting of polymersomes into Zhiyu Liu, Herong Shi, Anthony K. Nzessi, Anne Norris, Barth D. the cell nucleus Grant, and Jun Liu Christina Zelmer, Ludovit P. Zweifel, Larisa E. Kapinos, Ioana 2978 Modeling the transport of nuclear proteins along Craciun, Zekiye P. Gu¨ven, Cornelia G. Palivan, and Roderick Y. H. Lim single skeletal muscle cells Hermes Taylor-Weiner, Christopher L. Grigsby, Duarte M. S. 2886 RNA sequencing by direct tagmentation of Ferreira, Jose´ M. Dias, Molly M. Stevens, Jorge L. Ruas, RNA/DNA hybrids and Ana I. Teixeira Lin Di, Yusi Fu, Yue Sun, Jie Li, Lu Liu, Jiacheng Yao, Guanbo Wang, Yalei Wu, Kaiqin Lao, Raymond W. Lee, Genhua Zheng, ECOLOGY Jun Xu, Juntaek Oh, Dong Wang, X. Sunney Xie, Yanyi Huang, and Jianbin Wang 2987 Declines in an abundant aquatic insect, the burrowing mayfly, across major North American waterways BIOCHEMISTRY Phillip M. Stepanian, Sally A. Entrekin, Charlotte E. Wainwright, Djordje Mirkovic, Jennifer L. Tank, 2894 A precisely positioned MED12 activation helix and Jeffrey F. Kelly stimulates CDK8 kinase activity Felix Klatt, Alexander Leitner, Iana V. Kim, Hung Ho-Xuan, 2993 Reciprocity and behavioral heterogeneity govern the Elisabeth V. Schneider, Franziska Langhammer, Robin stability of social networks Weinmann, Melanie R. Mu¨ller, Robert Huber, Gunter Meister, Roslyn Dakin and T. Brandt Ryder and Claus-D. Kuhn 3000 Fire synchronizes flowering and boosts reproduction 2906 An RNA polymerase ribozyme that synthesizes its in a widespread but declining prairie species own ancestor Stuart Wagenius, Jared Beck, and Gretel Kiefer Katrina F. Tjhung, Maxim N. Shokhirev, David P. Horning, and Gerald F. Joyce ENVIRONMENTAL SCIENCES 2914 Skin permeability barrier formation by the ichthyosis- 3006 Ocean sentinel albatrosses locate illegal vessels and causative gene FATP4 through formation of the provide the first estimate of the extent of ω barrier lipid -O-acylceramide nondeclared fishing Haruka Yamamoto, Miku Hattori, Walee Chamulitrat, Yusuke Henri Weimerskirch, Julien Collet, Alexandre Corbeau, Adrien Ohno, and Akio Kihara Pajot, Floran Hoarau, Ce´dric Marteau, Dominique Filippi, 2923 Release of a disordered domain enhances HspB1 and Samantha C. Patrick chaperone activity toward tau 3015 The role of forest conversion, degradation, and Hannah E. R. Baughman, Thanh-Hau T. Pham, Chloe S. Adams, disturbance in the carbon dynamics of Amazon Abhinav Nath, and Rachel E. Klevit indigenous territories and protected areas Wayne S. Walker, Seth R. Gorelik, Alessandro Baccini, Jose Luis BIOPHYSICS AND COMPUTATIONAL BIOLOGY Aragon-Osejo, Carmen Josse, Chris Meyer, Marcia N. Macedo, 2795 Selectivity filter modalities and rapid inactivation of Cicero Augusto, Sandra Rios, Tuntiak Katan, Alana Almeida de the hERG1 channel Souza, Saul Cuellar, Andres Llanos, Irene Zager, Gregorio Dı´az Mirabal, Kylen K. Solvik, Mary K. Farina, Paulo Moutinho, Williams E. Miranda, Kevin R. DeMarco, Jiqing Guo, and Stephan Schwartzman Henry J. Duff, Igor Vorobyov, Colleen E. Clancy, and Sergei Yu. Noskov 2930 Combinatorial protein–protein interactions on EVOLUTION a polymerizing scaffold 3026 Impact of past climate warming on genomic diversity Andre´s Ortiz-Mun˜oz, He´ctor F. Medina-Abarca, and demographic history of collared lemmings and Walter Fontana across the Eurasian Arctic 2938 Conformational changes upon gating of KirBac1.1 Vadim B. Fedorov, Emiliano Trucchi, Anna V. Goropashnaya, into an open-activated state revealed by Eric Waltari, Susan Erin Whidden, and Nils Chr. Stenseth solid-state NMR and functional assays 3034 Ontogeny of the anuran urostyle and the Reza Amani, Collin G. Borcik, Nazmul H. Khan, Derek B. developmental context of evolutionary novelty Versteeg, Maryam Yekefallah, Hoa Q. Do, Heather R. Coats, Gayani Senevirathne, Stephanie Baumgart, Nathaniel Shubin, and Benjamin J. Wylie James Hanken, and Neil H. Shubin

Contents PNAS u February 11, 2020 u vol. 117 u no. 6 u v Downloaded by guest on September 25, 2021 3045 Evolutionary dynamics of recent selection on MEDICAL SCIENCES − − cognitive abilities 3123 Remethylation of Dnmt3a / hematopoietic cells Sara E. Miller, Andrew W. Legan, Michael T. Henshaw, is associated with partial correction of gene Katherine L. Ostevik, Kieran Samuk, Floria M. K. Uy, dysregulation and reduced myeloid skewing and Michael J. Sheehan Shamika Ketkar, Angela M. Verdoni, Amanda M. Smith, Celia V. Bangert, Elizabeth R. Leight, David Y. Chen, Meryl K. Brune, Nichole M. Helton, Mieke Hoock, GENETICS Daniel R. George, Catrina Fronick, Robert S. Fulton, 3053 Precision medicine integrating whole-genome Sai Mukund Ramakrishnan, Gue Su Chang, Allegra A. sequencing, comprehensive metabolomics, Petti, David H. Spencer, Christopher A. Miller, and advanced imaging and Timothy J. Ley Ying-Chen Claire Hou, Hung-Chun Yu, Rick Martin, Elizabeth T. 3135 FOXO1 and FOXO3 transcription factors have unique Cirulli, Natalie M. Schenker-Ahmed, Michael Hicks, functions in meniscus development and homeostasis Isaac V. Cohen, Thomas J. Jo¨nsson, Robyn Heister, during aging and osteoarthritis Lori Napier, Christine Leon Swisher, Saints Dominguez, Kwang Il Lee, Sungwook Choi, Tokio Matsuzaki, Oscar Haibao Tang, Weizhong Li, Bradley A. Perkins, Jaime Barea, Alvarez-Garcia, Merissa Olmer, Shawn P. Grogan, Darryl D. Christina Rybak, Emily Smith, Keegan Duchicela, Michael D’Lima, and Martin K. Lotz Doney, Pamila Brar, Nathaniel Hernandez, Ewen F. Kirkness, Andrew M. Kahn, J. Craig Venter, David S. Karow, 3144 Magnetic resonance imaging of glycogen using its and C. Thomas Caskey magnetic coupling with water Yang Zhou, Peter C. M. van Zijl, Xiang Xu, Jiadi Xu, Yuguo Li, Lin Chen, and Nirbhay N. Yadav IMMUNOLOGY AND INFLAMMATION 2751 Regulation of adipose tissue inflammation by 3150 Histamine receptor agonist alleviates severe interleukin 6 cardiorenal damages by eliciting anti- Myoung Sook Han, Alexis White, Rachel J. Perry, Joao-Paulo inflammatory programming Camporez, Juan Hidalgo, Gerald I. Shulman, Kazuyuki Noguchi, Junji Ishida, Jun-Dal Kim, Naoto and Roger J. Davis Muromachi, Koichiro Kako, Hayase Mizukami, Weizhe Lu, Tomohiro Ishimaru, Shohei Kawasaki, Shuzo See QnAs on page 2732 Kaneko, Joichi Usui, Hiroshi Ohtsu, Kunihiro Yamagata, 3063 A molecular basis for the T cell response in and Akiyoshi Fukamizu HLA-DQ2.2 mediated celiac disease 3157 Endothelial sphingosine 1-phosphate receptors Yi Tian Ting, Shiva Dahal-Koirala, Hui Shi Keshia Kim, promote vascular normalization and Shuo-Wang Qiao, Ralf S. Neumann, Knut E. A. antitumor therapy Lundin, Jan Petersen, Hugh H. Reid, Ludvig M. Sollid, Andreane Cartier, Tani Leigh, Catherine H. Liu, and Jamie Rossjohn and Timothy Hla 3074 Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-γ MICROBIOLOGY Alison G. Stanbery, Zachary R. Newman, and Gregory M. Barton 3167 Pseudomonas aeruginosa lasR mutant fitness in 3083 ECM1 is an essential factor for the determination of microoxia is supported by an Anr-regulated M1 macrophage polarization in IBD in response to oxygen-binding hemerythrin LPS stimulation Michelle E. Clay, John H. Hammond, Fangfang Zhong, Xiaolei Chen, Caitlin H. Kowalski, Alexandra J. Lee, Monique S. Porter, Yaguang Zhang, Xuezhen Li, Zhongguang Luo, Liyan Thomas H. Hampton, Casey S. Greene, Ekaterina V. Pletneva, Ma, Songling Zhu, Zhishuo Wang, Jing Wen, Shipeng and Deborah A. Hogan Cheng, Wangpeng Gu, Qiaoshi Lian, Xinhao Zhao, Weiguo Fan, Zhiyang Ling, Jing Ye, Songguo 3174 Orchestration of human macrophage NLRP3 Zheng, Dangsheng Li, Hongyan Wang, Jie Liu, inflammasome activation by Staphylococcus and Bing Sun aureus extracellular vesicles 3093 Allosteric activation of MALT1 by its ubiquitin- Xiaogang Wang, William J. Eagen, and Jean C. Lee binding Ig3 domain 3185 Antibiotic resistance by high-level intrinsic Rebekka Schairer, Gareth Hall, Ming Zhang, Richard Cowan, suppression of a frameshift mutation in Roberta Baravalle, Frederick W. Muskett, Peter J. Coombs, an essential gene Chido Mpamhanga, Lisa R. Hale, Barbara Saxty, Justyna Douglas L. Huseby, Gerrit Brandis, Lisa Praski Alzrigat, Iwaszkiewicz, Chantal De´caillet, Mai Perroud, Mark D. Carr, and Diarmaid Hughes and Margot Thome 3103 IL-4 controls activated neutrophil FcγR2b expression NEUROSCIENCE and migration into inflamed joints Sudeepta Kumar Panda, Gustaf Wigerblad, Long Jiang, 2835 Wireless, battery-free subdermally implantable Yanek Jime´nez-Andrade, Vaishnavi Srinivasan Iyer, photometry systems for chronic recording of Yunbing Shen, Sanjaykumar V. Boddul, Andre´ Ortlieb neural dynamics Guerreiro-Cacais, Bruno Raposo, Zsolt Kasza, Alex Burton, Sofian N. Obaid, Abraham Va´zquez-Guardado, and Fredrik Wermeling Matthew B. Schmit, Tucker Stuart, Le Cai, Zhiyuan Chen, 3114 Optimization of a Plasmodium falciparum Irawati Kandela, Chad R. Haney, Emily A. Waters, Haijiang Cai, John A. Rogers, Luyao Lu, and Philipp Gutruf circumsporozoite protein repeat vaccine using the tobacco mosaic virus platform 3192 GABA-mediated tonic inhibition differentially Mark D. Langowski, Farhat A. Khan, Alexis A. Bitzer, modulates gain in functional subtypes of Christopher J. Genito, Andrew J. Schrader, Monica L. Martin, cortical interneurons Kimberly Soto, Xiaoyan Zou, Sri Hadiwidjojo, Zoltan Beck, Alexander Bryson, Robert John Hatch, Bas-Jan Zandt, Christian Gary R. Matyas, Merricka C. Livingstone, Adrian H. Batchelor, Rossert, Samuel F. Berkovic, Christopher A. Reid, David B. and Sheetij Dutta Grayden, Sean L. Hill, and Steven Petrou

vi u www.pnas.org Contents Downloaded by guest on September 25, 2021 3203 Transformation of speech sequences in human SUSTAINABILITY SCIENCE sensorimotor circuits 2864 Diversity buffers winegrowing regions from climate Kathrin Mu¨sch, Kevin Himberger, Kean Ming Tan, Taufik A. change losses Valiante, and Christopher J. Honey Ignacio Morales-Castilla, In˜aki Garcı´a de Corta´zar-Atauri, 3214 SYNPLA, a method to identify synapses displaying Benjamin I. Cook, Thierry Lacombe, Amber Parker, plasticity after learning Cornelis van Leeuwen, Kimberly A. Nicholas, and Elizabeth M. Wolkovich Kim Dore, Yvonne Pao, Jose Soria Lopez, Sage Aronson, Huiqing Zhan, Sanchari Ghosh, Sabina Merrill, Anthony M. Zador, Roberto Malinow, and Justus M. Kebschull SYSTEMS BIOLOGY 3220 A qualitative solution with quantitative potential for 3301 Genome-scale transcriptional dynamics and the mouse hippocampal cortex flatmap problem environmental biosensing Larry W. Swanson and Joel D. Hahn Garrett Graham, Nicholas Csicsery, Elizabeth Stasiowski, 3232 Simple spike dynamics of Purkinje cells in the Gregoire Thouvenin, William H. Mather, Michael Ferry, Scott macaque vestibulo-cerebellum during passive Cookson, and Jeff Hasty whole-body self-motion 3307 Reassessing enzyme kinetics: Considering Jean Laurens and Dora E. Angelaki protease-as-substrate interactions in 3239 Serotonergic afferents from the dorsal raphe proteolytic networks decrease the excitability of pyramidal neurons Meghan C. Ferrall-Fairbanks, Chris A. Kieslich, in the anterior piriform cortex and Manu O. Platt Dejuan Wang, Xiaojie Wang, Penglai Liu, Siqi Jing, Han Du, 3319 Designing effective control of dengue with Lingzhi Zhang, Fan Jia, and Anan Li combined interventions 3248 Conservative and disruptive modes of adolescent Thomas J. Hladish, Carl A. B. Pearson, Kok Ben Toh, change in human brain functional connectivity Diana Patricia Rojas, Pablo Manrique-Saide, Gonzalo M. Vazquez-Prokopec, M. Elizabeth Halloran, Frantisek Va´sa, Rafael Romero-Garcia, Manfred G. Kitzbichler, and Ira M. Longini Jr Jakob Seidlitz, Kirstie J. Whitaker, Matilde M. Vaghi, Prantik Kundu, Ameera X. Patel, Peter Fonagy, Raymond J. Dolan, 3326 Molecular adaptations of the blood–brain barrier Peter B. Jones, Ian M. Goodyer, the NSPN Consortium, promote stress resilience vs. depression Petra E. Ve´rtes, and Edward T. Bullmore Katarzyna A. Dudek, Laurence Dion-Albert, Manon 3254 Removing a single neuron in a vertebrate brain Lebel, Katherine LeClair, Simon Labrecque, Ellen Tuck, forever abolishes an essential behavior Carmen Ferrer Perez, Sam A. Golden, Carol Tamminga, Gustavo Turecki, Naguib Mechawar, Scott J. Russo, Alexander Hecker, Wolfram Schulze, Jakob Oster, David O. and Caroline Menard Richter, and Stefan Schuster

PLANT BIOLOGY CORRECTIONS 3261 Central clock components modulate plant shade avoidance by directly repressing transcriptional APPLIED PHYSICAL SCIENCES activation activity of PIF proteins 3337 Wildfire prevention through prophylactic treatment Yu Zhang, Anne Pfeiffer, James M. Tepperman, Jutta of high-risk landscapes using viscoelastic Dalton-Roesler, Pablo Leivar, Eduardo Gonzalez Grandio, and Peter H. Quail retardant fluids Anthony C. Yu, Hector Lopez Hernandez, Andrew H. Kim, 3270 Mapping proteome-wide targets of protein kinases in Lyndsay M. Stapleton, Reuben J. Brand, Eric T. Mellor, plant stress responses Cameron P. Bauer, Gregory D. McCurdy, Albert J. Wolff III, Pengcheng Wang, Chuan-Chih Hsu, Yanyan Du, Peipei Zhu, Doreen Chan, Craig S. Criddle, Jesse D. Acosta, Chunzhao Zhao, Xing Fu, Chunguang Zhang, Juan Sebastian and Eric A. Appel Paez, Alberto P. Macho, W. Andy Tao, and Jian-Kang Zhu 3281 ARABIDOPSIS DEHISCENCE ZONE ANTHROPOLOGY POLYGALACTURONASE 1 (ADPG1) releases latent 3338 Insights into the lower torso in late Miocene hominoid defense signals in stems with reduced lignin content Oreopithecus bambolii Lina Gallego-Giraldo, Chang Liu, Sara Pose-Albacete, Ashley S. Hammond, Lorenzo Rook, Alisha D. Anaya, Sivakumar Pattathil, Angelo Gabriel Peralta, Jenna Young, Jan Elisabetta Cioppi, Loı¨c Costeur, Salvador Moya`-Sola`, Westpheling, Michael G. Hahn, Xiaolan Rao, J. Paul Knox, and Sergio Alme´cija Barbara De Meester, Wout Boerjan, and Richard A. Dixon 3339 Association of EGLN1 gene with high aerobic capacity of Peruvian Quechua at high altitude PSYCHOLOGICAL AND COGNITIVE SCIENCES Tom D. Brutsaert, Melisa Kiyamu, Gianpietro Elias 3291 Uncertainty in learning, choice, and visual fixation Revollendo, Jenna L. Isherwood, Frank S. Lee, Maria Hrvoje Stojic, Jacob L. Orquin, Peter Dayan, Raymond J. Rivera-Ch, Fabiola Leon-Velarde, Sudipta Ghosh, Dolan, and Maarten Speekenbrink and Abigail W. Bigham

Contents PNAS u February 11, 2020 u vol. 117 u no. 6 u vii Downloaded by guest on September 25, 2021