Because of You

Total Page:16

File Type:pdf, Size:1020Kb

Because of You because of you 2014 Report of Donors UMass Medical School + UMass Memorial Health Care Table of Contents Anonymous donors to CANDO Clinic meet their match ................................................................ 2 Inspired by Gov. Cellucci, Riccios give $1M for ALS research at UMMS ....................................... 4 Cover lab photo – bottom left: Peter Vanderwarker Research fund renamed to honor Gov. Cellucci ............................................................................. 5 Supporting tomorrow’s physicians .................................................................................................... 6 Endowed scholarship aims to help meet need for more primary care physicians Parents of UMMS graduate pledge to endow scholarship for medical education The bone paradox Research into a puzzling disease gains substantial and meaningful support ................... 8 2014 a notable year for reunions and alumni contributions to financial aid ............................... 9 A “random” act of kindness benefits pediatric patients ............................................................... 10 Putting abilities to work in Massachusetts ..................................................................................... 12 A “pioneering force” for mindfulness inspires giving ................................................................... 14 Spirited rubber duck race fundraiser marks 10 years of support for Child Life Program ......... 16 Donor-funded research promises to be “the epitome of personalized cancer treatment” ...... 17 Parents channel their loss into helping others .............................................................................. 18 Fundraising for the 15th annual UMass Medicine Cancer Walk exceeds $500,000 goal ..........20 Passionate support for pancreatic cancer research and care ..................................................... 21 because of you Notable events ...................................................................................................................................22 A year in review.................................................................................................................................24 Our donors .........................................................................................................................................26 UMass Medicine 2014 Annual Donor Report | 1 from the leadership Actively contributing to the betterment of our local and global communities is at the heart of our mission. It drives the decisions we make each and every day that enable us to offer an outstanding medical education, to advance basic and translational research, and to provide the best quality health care. These endeavors are strengthened and made more effective because of you. As you will see in the pages of Michael F. Collins, MD this annual report, the remarkable support we receive Chancellor from individuals and community groups, alumni and University of Massachusetts Medical School parents, and corporations and foundations serves to Senior Vice President for the Health Sciences broaden and deepen our reach as well as strengthen University of Massachusetts the impact of our work. Because of you, scholarships have been created to support the health care providers of tomorrow; an interdisciplinary clinic has been established—the first of its kind in our area—to provide critically needed evaluations and short-term services for children with autism and other neurodevelopmental disorders; and physician-scientists are collaborating on innovative research that may one day inform personalized cancer treatment. Because of you, working-age adults with disabilities are being empowered to find meaningful and gainful Eric W. Dickson, MD, MHCM, FACEP employment; pediatric patients can access a variety President and CEO of recreational and therapeutic opportunities to help UMass Memorial Health Care them deal with the stress of being in the hospital; parents and families of our tiniest patients will have a comfortable place to go within our NICU when they most need privacy; and our ALS research efforts continue to receive tremendous support. Because of you, our academic health sciences system is making a tremendous impact—and we are extremely grateful for your support. 2 | 2014 Annual Donor Report UMass Medicine Anonymous donors to CANDO Clinic meet their match In June 2013, the Center for Autism and Neurodevelopmental Disorders (CANDO) Clinic—the first-ever interdisciplinary autism disorder clinic in Metro West and Central Massachusetts—was launched. A joint effort of UMass Ty, age 6, participates in a weekly therapy session in Medical School and UMass Memorial Health Care, the the Gym at the CANDO Clinic, which provides patients like CANDO Clinic is a single point of entry that provides timely, Ty with opportunities to engage in motivating and fun movement activities that help with regulating attention for initiating and comprehensive evaluations and short-term treatment services. engaging in social interactions. Recognizing the clinic’s critical importance to the commu- “It’s really difficult,” said Brandy Melhouse, whose son nity, an anonymous donor family helped launch the CANDO Nathan was diagnosed with autism at age 5. “You don’t know effort with a $500,000 gift. They also offered a challenge where to go and when you do get in to see a doctor, you get match opportunity that would maximize the impact of phil- a piece of paper with some recommendations on it and then anthropic support for the clinic: If an additional $500,000 was you’re sent off. We went to CANDO where they will connect raised for CANDO by June 30, 2014, the donor family would those pieces for you.” match it dollar for dollar. That match was met. Services at the clinic are provided by a combination of “It was exhilarating to see such backing for the CANDO specialists at every stage of patient care, from evaluation and Clinic,” said Jean A. Frazier, MD, the Robert M. and Shirley S. treatment to transitioning to community providers. The clinic Siff Chair in Autism, professor of psychiatry and pediatrics, is also uniquely positioned to further scientific understanding and medical director of CANDO. “Knowing that people of autism spectrum and other neurodevelopmental disorders. believe in and support the work that we’re doing—and that “One of the advantages our relationship with the Medical we will be able to move forward with this effort because of School gives the health system is that it allows us to attract that support—is tremendous.” world-class talent into the Worcester area,” said Eric W. In early 2013, it was reported that the CDC now estimates Dickson, MD, MHCM, FACEP, president and CEO of UMass that about one in 50 children in the U.S. have been identified Memorial Health Care. “The CANDO Clinic is the perfect with an autism spectrum disorder (ASD). Most are diagnosed example of that.” after they reach the age of 4, and research shows that early “Our long-term plan is to provide a permanent integrated detection and treatment greatly improves a child’s develop- clinical, research and teaching clinic for patients with ment and future. ASD and other neurodevelopmental disorders across the For children with an ASD and their families living in lifespan,” said Frazier. “Launching the CANDO Clinic was Greater Worcester, facilities offering comprehensive the first step.” diagnosis and treatment—at an average wait time of nine While operational support from UMMS and UMass to 18 months—had only been available in or near Boston. Memorial provides the foundation for the clinic, Frazier also “We were really excited to start this clinic because noted that traditional insurance reimbursements do not in Metro West, Central Massachusetts and Western begin to cover the costs of providing services, which means Massachusetts there had not been a clinic that served multi- that private funding is an essential part of starting and complex children and children with autism,” said Dr. Frazier. maintaining this initiative. UMass Medicine 2014 Annual Donor Report | 3 “We anticipated that only half of the cost of the butions were all matched by that anonymous 20-week CANDO program would be covered by donor family. insurance reimbursement,” she said. “With additional resources, we can make our Substantial support was provided by a variety of clinic available to more families and children,” said foundations, corporations and individuals (see list) Michael F. Collins, MD, chancellor of UMass Medical and from the 2013 UMass Medicine Winter Ball, at School. “We can conduct groundbreaking research, which $150,000 was raised during the Fund-A-Need we can establish partnerships with payers, and most Jean A. Frazier, MD auction, the centerpiece of this annual fundraising importantly, we can make a big difference in the lives Robert M. and Shirley S. gala (see related story on page 22). These contri- of children and the health of their families.” Siff Chair in Autism Professor of Psychiatry and Pediatrics Medical Director of CANDO Donors to the CANDO Clinic $10,000 and Above Shannon Creedon and John Creedon Jr. Faye Levine and Alvin Meisel Anonymous (4) Cristina and Zoltan Csimma Meisel Family Foundation, Inc. Herman F. Becker Family Charitable Foundation, Inc. Michelle and Robert Currie Edit Mello and Dr. Craig C. Mello Mrs. Herman F. Becker Therese and W. David Day Miss Worcester Diner Phillip D. Zamore and Catherine M. Colinvaux Mary C. DeFeudis Moe’s Southwest Grill Commerce Bank
Recommended publications
  • IICSA Inquiry Roman Catholic Church Investigation Wider Hearing 8 November 2019
    IICSA Inquiry Roman Catholic Church Investigation Wider Hearing 8 November 2019 1 Friday, 8 November 2019 1 I indicate, therefore, there are some additional 2 (10.30 am) 2 statements from the NCSC witnesses, both past and 3 THE CHAIR: Good morning, everyone. Welcome to the final 3 present, from Rachel O'Driscoll, Elizabeth Manero, whom 4 day of this public hearing. Ms Carey? 4 we have heard of, and a past member called 5 Housekeeping 5 Susie Hayward. 6 MS CAREY: Good morning, chair. Before we turn to closing 6 From Ofsted there is a statement of Sean Harford. 7 submissions on behalf of the core participants this 7 Chair, you will be familiar with Adrian Child. There is 8 morning, may I deal with one matter of formality? 8 an additional statement from the former director of 9 During the course of this two-week public hearing, there 9 CSAS. In addition to the statements read out yesterday 10 has been reference to a number of documents, statements 10 in relation to formation, the inquiry intends to publish 11 and exhibits that will be published on the inquiry 11 those statements from Reverend Taylor, 12 website, and a list is going to be published on the 12 Monsignor Whitmore and, indeed, Canon Farrer and 13 website later today, along with the unique Relativity 13 Canon Coyle, whom you heard from yesterday. 14 references for those documents. 14 Chair, in respect of the review by the Westminster 15 A number have already been referred to during the 15 Diocese of the safeguarding file in respect of RC-A711, 16 course of the live evidence, but there are some 16 Monsignor O'Boyle's statement will be published.
    [Show full text]
  • Health Policy for Low-Income People: Profiles of 13 States
    Health Policy for Low-Income People: Profiles of 13 States Amy Westpfahl Lutzky John Holahan Joshua M. Wiener The Urban Institute Occasional Paper Number 57 Assessing the New Federalism An Urban Institute Program to Assess Changing Social Policies Health Policy for Low-Income People: Profiles of 13 States Amy Westpfahl Lutzky John Holahan Joshua M. Wiener The Urban Institute Contributing Authors Randall R. Bovbjerg Amy Westpfahl Lutzky Niall Brennan Barbara Ormond Brian K. Bruen Mary Beth Pohl Julie Chesky Jane Tilly Teresa A. Coughlin Frank C. Ullman Ian Hill Joshua M. Wiener John Holahan Alyssa Wigton Stephanie Kendall Alshadye Yemane Sharon K. Long Stephen Zuckerman Occasional Paper Number 57 The Urban Institute 2100 M Street, N.W. Washington, DC 20037 Phone: 202.833.7200 Fax: 202.429.0687 E-Mail: [email protected] An Urban Institute Program to Assess http://www.urban.org Changing Social Policies Copyright © May 2002. The Urban Institute. All rights reserved. Except for short quotes, no part of this book may be reproduced in any form or utilized in any form by any means, electronic or mechanical, including pho- tocopying, recording, or by information storage or retrieval system, without written permission from the Urban Institute. This paper is part of the Urban Institute’s Assessing the New Federalism project, a multiyear project to monitor and assess the devolution of social programs from the federal to the state and local levels. Alan Weil is the proj- ect director. The project analyzes changes in income support, social services, and health programs. In collabora- tion with Child Trends, the project studies child and family well-being.
    [Show full text]
  • Biogen Idec Announces Major Gift to Umass
    FOR IMMEDIATE RELEASE March 15, 2012 Contact: Office of Communications [email protected] 508-856-2000 BIOGEN IDEC JOINS FORMER MASSACHUSETTS GOVERNORS PAUL CELLUCCI AND BILL WELD TO ANNOUNCE MAJOR GIFT TO UMASS/ALS CHAMPION FUND Politicians past and present alongside Governors for event to benefit ALS research BOSTON, MA – The University of Massachusetts Medical School (UMMS) today announced a $500,000 gift from Biogen Idec to the UMass/ALS Champion Fund, which supports critical research into ALS and other neurodegenerative diseases. Biogen Idec CEO George A. Scangos, Ph.D., presented the gift to former Massachusetts Governor Paul Cellucci, who launched the Champion Fund last year shortly after announcing that he had been diagnosed with ALS, or Lou Gehrig’s disease. In recognition of the critical need for new treatments for ALS, the UMass/ALS Champion Fund is a campaign to raise awareness and funding for the world-class neuroscience research happening in the UMMS neurology department, which is chaired by Robert H. Brown, Jr., D.Phil., M.D., director of the Day Neuromuscular Research Laboratory at UMMS and one of the world’s leading ALS researchers. “I am so moved by the generosity of Biogen Idec – a great Massachusetts corporation,” said Governor Cellucci. “One of the greatest national resources we have is found in abundance right here in the Commonwealth, in companies like Biogen Idec that are committed to developing cures and treatments that change millions of lives.” “I thank Dr. Scangos and his company. Their generous gift will help support the incredible research into potential treatments for ALS and other neurodegenerative diseases being done at UMass Medical School,” said the Governor.
    [Show full text]
  • 2018 SUGAR BOWL FACT SHEET CLEMSON TIGERS ALABAMA CRIMSON TIDE VERSUS 2017 Record 12-1 (7-1 ACC) 2017 Record 11-1 (7-1 SEC) Rankings No
    2018 SUGAR BOWL FACT SHEET CLEMSON TIGERS ALABAMA CRIMSON TIDE VERSUS 2017 Record 12-1 (7-1 ACC) 2017 Record 11-1 (7-1 SEC) Rankings No. 1 CFP, No. 1 AP, No. 1 USA Today Ranking No. 4 CFP, No. 4 AP, No. 4 USA Today Location Clemson, S.C. Location Tuscaloosa, Ala. Colors Tiger Orange & Regalia Colors Crimson & White Enrollment 24,387 Enrollment 38,563 Head Coach Dabo Swinney (Alabama ‘93) Head Coach Nick Saban (Kent State ‘73) Overall Record at Clemson (seasons) 101-29 (10th) Overall Record at Alabama (seasons) 125-20 (11th) Home Record at Clemson 59-7 Bowl Record at Alabama 8-4 Away/Neutral Record at Clemson 42-22 Career Overall Record (seasons) 216-62-1 (22nd) Bowl Record at Clemson 7-4 Career Record vs. Clemson 2-1 ACC Regular-Season Record 61-16 Offensive Coordinator Brian Daboll Career Overall Record (seasons) 101-29 (10th) Defensive Coordinator Jeremy Pruitt Career Record vs. Alabama 1-1 Athletic Communications Contact Josh Maxson Offensive Coordinators Tony Elliott, Jeff Scott Cell Phone 205-242-5917 Defensive Coordinator Brent Venables Email [email protected] Athletic Website ClemsonTigers.com Athletic Website RollTide.com ATHLETIC COMMUNICATIONS FBS STAT RANKING COMPARISON Primary Football Contact Tim Bourret (Notre Dame ‘77) CLEMSON VS. ALABAMA Category Clemson Alabama Cell Phone 864-356-3791 Winning Percentage 92.3 (T-2) 91.7 (6) Email [email protected] MONDAY • JAN. 1, 2018 Scoring Offense 35.4 (21) 39.1 (12) Secondary Football Contact Brian Hennessy (Clemson ‘98) 8:45 p.m. EST Scoring Defense 12.8 (2) 11.5 (1) Cell Phone 864-986-9046 Mercedes-Benz Superdome (72,500) Total Offense 448.1 (31) 465.4 (20) Email [email protected] New Orleans, La.
    [Show full text]
  • ERC Advanced Grant 2008 Project Acronym Title Principal Investigator Host Institution Host Country 226037 NSYS Nonlinear System
    ERC Advanced Grant 2008 Project Acronym Title Principal Investigator Host Institution Host Country Nonlinear System Identification and Analysis in the Time, Prof. Stephen Alec 226037 NSYS THE UNIVERSITY OF SHEFFIELD UK Frequency, and Spatio-Temporal Domains Billings HOWTOCONT Search for mechanisms to control massless electrons in 226043 ROLGRAPHE Prof. Carlo Beenakker UNIVERSITEIT LEIDEN. NL graphene NE THE HEBREW UNIVERSITY OF 226135 EXPANDERS Expander Graphs in Pure and Applied Mathematics Prof. Alexander Lubotzky IL JERUSALEM. 226136 VISCHEM Visualizing Molecular Change Prof. Villy Sundström LUNDS UNIVERSITET SE Consistent computation of the chemistry-cloud THE CYPRUS RESEARCH AND 226144 C8 Prof. Johannes Lelieveld CY continuum and climate change in Cyprus EDUCATIONAL FOUNDATION Modern Approaches to Temperature Reconstructions in 226172 MATRICS Dr. Hubertus Fischer UNIVERSITAET BERN CH polar Ice Cores FUndamental studies and innovative appROaches of Prof. Roland Martin 226180 FURORE UNIVERSITAET HAMBURG DE REsearch on magnetism Wiesendanger EBERHARD KARLS 226187 SOCATHES Solid State/Cold Atom Hybrid Quantum Devices Prof. Reinhold Kleiner DE UNIVERSITAET TUEBINGEN KUNGLIGA TEKNISKA 226203 APPROXNP Approximation of NP-hard optimization problems Prof. Johan Håstad SE HOEGSKOLAN Patchy colloidal particles: a powerful arsenal for the PATCHYCOLL fabrication of tomorrow new super-molecules . A UNIVERSITA DEGLI STUDI DI 226207 Prof. Francesco Sciortino IT OIDS theoretical and numerical study of their assembly ROMA LA SAPIENZA processes. ERC Advanced Grant 2008 Analytic Techniques for Geometric and Functional UNIVERSITA DEGLI STUDI DI 226234 ANTEGEFI Prof. Nicola Fusco IT Inequalities NAPOLI FEDERICO II. Multiscale Models for Catalytic-Reaction-Coupled 226238 MMFCS Prof. Bengt Sundén LUNDS UNIVERSITET SE Transport Phenomena in Fuel Cells WEIZMANN INSTITUTE OF 226246 NANOSQUID Scanning Nano-SQUID on a Tip Prof.
    [Show full text]
  • Nature Medicine Essay
    COMMENTARY LASKER BASIC MEDICAL RESEARCH AWARD Of maize and men, or peas and people: case histories to justify plants and other model systems David Baulcombe One of the byproducts of molecular biology cork is altogether filled with air, and that air is has been support for the ‘model system’ con- perfectly enclosed in little boxes or cells distinct cept. All living organisms are based on the same from one another.”)2 (Fig. 1). Two hundred fifty genetic code, they have similar subcellular years later, Beijerinck discovered a contagium structures and they use homologous metabolic vivum fluidum in extracts of diseased tobacco pathways. So, mechanisms can be investigated plants that he later referred to as a virus3. using organisms other than those in which In contemporary science, a green alga— the knowledge will be exploited for practical Chlamydomonas reinhardtii—is a useful model benefit. Model systems are particularly use- in the analysis of kidney disease4. However, ful in the early discovery phase of a scientific in this article, I refer to the contribution of endeavor, and recent progress in biomedical plant biology to a family of mechanisms that I science has fully vindicated their use. Jacques refer to as RNA silencing. This topic has been Monod, for example, famously justified his reviewed comprehensively elsewhere5,6, so here work on a bacterial model system by stating I focus on personal experience and my view of that “what is true for Escherichia coli is also future potential from this work. true for elephants.” My fellow laureates, Victor Ambros and Gary Ruvkun, can defend the use The early history of RNA silencing in of the worm Caenorhabditis elegans as a good plants model system and so I will focus on plants.
    [Show full text]
  • Central Intelligence Agency (CIA) Freedom of Information Act (FOIA) Case Log October 2000 - April 2002
    Description of document: Central Intelligence Agency (CIA) Freedom of Information Act (FOIA) Case Log October 2000 - April 2002 Requested date: 2002 Release date: 2003 Posted date: 08-February-2021 Source of document: Information and Privacy Coordinator Central Intelligence Agency Washington, DC 20505 Fax: 703-613-3007 Filing a FOIA Records Request Online The governmentattic.org web site (“the site”) is a First Amendment free speech web site and is noncommercial and free to the public. The site and materials made available on the site, such as this file, are for reference only. The governmentattic.org web site and its principals have made every effort to make this information as complete and as accurate as possible, however, there may be mistakes and omissions, both typographical and in content. The governmentattic.org web site and its principals shall have neither liability nor responsibility to any person or entity with respect to any loss or damage caused, or alleged to have been caused, directly or indirectly, by the information provided on the governmentattic.org web site or in this file. The public records published on the site were obtained from government agencies using proper legal channels. Each document is identified as to the source. Any concerns about the contents of the site should be directed to the agency originating the document in question. GovernmentAttic.org is not responsible for the contents of documents published on the website. 1 O ct 2000_30 April 2002 Creation Date Requester Last Name Case Subject 36802.28679 STRANEY TECHNOLOGICAL GROWTH OF INDIA; HONG KONG; CHINA AND WTO 36802.2992 CRAWFORD EIGHT DIFFERENT REQUESTS FOR REPORTS REGARDING CIA EMPLOYEES OR AGENTS 36802.43927 MONTAN EDWARD GRADY PARTIN 36802.44378 TAVAKOLI-NOURI STEPHEN FLACK GUNTHER 36810.54721 BISHOP SCIENCE OF IDENTITY FOUNDATION 36810.55028 KHEMANEY TI LEAF PRODUCTIONS, LTD.
    [Show full text]
  • 3718 Issue63july2010 1.Pdf
    Issue 63.qxd:Genetic Society News 1/10/10 14:41 Page 1 JULYJULLYY 2010 | ISSUEISSUE 63 GENETICSGENNETICSS SOCIETYSOCIEETY NENEWSEWS In this issue The Genetics Society NewsNewws is edited by U Genetics Society PresidentPresident Honoured Honoured ProfProf David Hosken and items ittems for future future issues can be sent to thee editor,editor, preferably preferably U Mouse Genetics Meeting by email to [email protected],D.J.Hosken@@exeter.ac.uk, or U SponsoredSponsored Meetings Meetings hardhard copy to Chair in Evolutionary Evoolutionary Biology, Biology, UniversityUniversity of Exeter,Exeter, Cornwall Cornnwall Campus, U The JBS Haldane LectureLecture Tremough,Tremough, Penryn, TR10 0 9EZ UK.UK. The U Schools Evolutionn ConferenceConference Newsletter is published twicet a year,year, with copy dates of 1st June andand 26th November.November. U TaxiTaxi Drivers The British YeastYeaste Group Group descend on Oxford Oxford for their 2010 meeting: m see the reportreport on page 35. 3 Image © Georgina McLoughlin Issue 63.qxd:Genetic Society News 1/10/10 14:41 Page 2 A WORD FROM THE EDITOR A word from the editor Welcome to issue 63. In this issue we announce a UK is recognised with the award of a CBE in the new Genetics Society Prize to Queen’s Birthday Honours, tells us about one of Welcome to my last issue as join the medals and lectures we her favourite papers by Susan Lindquist, the 2010 editor of the Genetics Society award. The JBS Haldane Mendel Lecturer. Somewhat unusually we have a News, after 3 years in the hot Lecture will be awarded couple of Taxi Drivers in this issue – Brian and seat and a total of 8 years on annually to recognise Deborah Charlesworth are not so happy about the committee it is time to excellence in communicating the way that the print media deals with some move on before I really outstay aspects of genetics research to scientific issues and Chris Ponting bemoans the my welcome! It has been a the public.
    [Show full text]
  • 081Template.Pdf
    33 Conwell Drive Maple Glen, PA 19002 September 26th, 2021 (215) 646-4600 • (215) 646-0180 (Fax) The 26th Sunday in Ordinary Time [email protected] www.stalphonsusparish.org ———————————— Rev. Msgr. Brian P. Hennessy, Pastor Most Rev. Timothy C. Senior, Assisting Rev. Keith Chylinski, Assisting Deacon John Mischler Deacon James (JT) Toth Mary Frances Kelly Parish Services Director Sandra Lowery Business Manager Michele Gordon Director of Religious Education [email protected] P.R.E.P. (215) 643-7938 Jeffrey Clements Director of Communications & IT Dear Parishioners, Fran La Noce [email protected] As the busyness of the fall begins, I invite all of us to remember to keep prayer Parish Faith Director the cornerstone of our lives. Prayer allows us to maintain that healthy and holy balance of life which we all need and helps us to draw upon the strength of God without which Frank Stieber we can quickly lose perspective and become overwhelmed. The following is a catechesis Director of Music Ministry by Pope Francis on prayer, which he offered on June 9th at his Wednesday Audience. (215) 542-8319 ———————————— God bless your week and let us pray for one another! PARISH OFFICE HOURS Monday–Thursday 9:00 am – 5:00 pm Sincerely in Christ, Friday 9:00 am - 3:00 pm Monsignor Hennessy MASS SCHEDULES In this penultimate catechesis on prayer we are going to speak about persever- Saturday Vigil 5:00 pm ance in praying. It is an invitation, indeed, a command that comes to us from Sacred Sunday 8:00 am, 10:15 am, 12 Noon Scripture.
    [Show full text]
  • Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA
    GENE SILENCING BY DOUBLE STRANDED RNA Nobel Lecture, December 8, 2006 by Andrew Z. Fire Departments of Pathology and Genetics, Stanford University School of Medicine, 300 Pasteur Drive, Room L235, Stanford, CA 94305-5324, USA. I would like to thank the Nobel Assembly of the Karolinska Institutet for the opportunity to describe some recent work on RNA-triggered gene silencing. First a few disclaimers, however. Telling the full story of gene silencing would be a mammoth enterprise that would take me many years to write and would take you well into the night to read. So we’ll need to abbreviate the story more than a little. Second (and as you will see) we are only in the dawn of our knowledge; so consider the following to be primer... the best we could do as of December 8th, 2006. And third, please understand that the story that I am telling represents the work of several generations of biologists, chemists, and many shades in between. I’m pleased and proud that work from my labo- ratory has contributed to the field, and that this has led to my being chosen as one of the messengers to relay the story in this forum. At the same time, I hope that there will be no confusion of equating our modest contributions with those of the much grander RNAi enterprise. DOUBLE STRANDED RNA AS A BIOLOGICAL ALARM SIGNAL These disclaimers in hand, the story can now start with a biography of the first main character. Double stranded RNA is probably as old (or almost as old) as life on earth.
    [Show full text]
  • April 18, 2021 Page 1 April 18, 2021
    April 18, 2021 Page 1 April 18, 2021 Page 2 Third Sunday of Easter Stewardship Thoughts—April 18, 2021 A Note From The themes linked in today’s Scripture readings encourage us to avoid sin by following the Lord’s directives, to repent, Our Pastor and to seek forgiveness. St. Peter, in the Acts of the Apostles, reminds the people, and us, of the evil of Christ’s THE EASTER SEASON passion and death, and that through repentance and conversion, our sins be wiped away. St. John, in his First The weeks between Easter and Pentecost are above all the Letter, tells us that Jesus is an offering for our sins. In St. seasons of the Church liturgical year, the time of Christian Luke’s Gospel, Jesus appears to His disciples after His joy. The joy of knowing that the Lord is risen to everlasting Resurrection while two of them recount their encounter life, the joy of sharing in His resurrection through baptism with Jesus on the road to Emmaus. They finally recognize and Eucharist, the joy of anticipation of the Heavenly Feast Him in the breaking of the bread. The Church has long of the world to come, the joy of living with our hearts lifted taught that partaking of the Eucharist strengthens us on up with Christ in a world redeemed and reconciled with the our journey as Christ’s disciples. Likewise, participating in Father, and the joy of being called to be ministers in the the Sacrament of Reconciliation for the forgiveness of sins world of the victory of Christ.
    [Show full text]
  • Representative Robert A. Durand
    Berkshire Woods and Waters: Durand named to Fisheries and Wildlife Board BY GENE C HAGUE, Eagle correspondent Saturday, May 25, 2019 Robert Durand is sworn in as a member of the state's Fisheries and Wildlife Board of Directors by Lt. Gov. Karyn Polito, right, as his wife Nancy watches on. Governor Charlie Baker has named Robert A. Durand, president of Durand & Anastas Environmental Strategies, an environmental consulting and lobbying firm, to the Massachusetts Fisheries and Wildlife Board. Lieutenant Governor Karyn Polito conducted the swearing-in ceremony for the five-year term last Wednesday. State Rep. William “Smitty” Pignatelli, D-Lenox, Chairman of the Joint Committee on Environment, Natural Resources and Agriculture, was one of about 10 Representatives and Senators who attended the swearing in. Smitty said some nice words and reminded everyone of how close Bob was to the late George (Gige) Darey. “I am so pleased and honored to receive this nomination to the board, which has been a part of my life in one way or another for most of my life,” Durand said. “I’m thankful to Gov. Baker and Lt. Gov. Polito for their confidence in me to carry out this vital mission to protect many critical aspects of our natural world, and with it, our quality of life in Massachusetts.” As one of the seven-member board, Durand will represent the Northeast Region, Middlesex and Essex counties, and replaces Fred Winthrop, who resigned from the board last fall. The board has various duties, including writing and overseeing all hunting and fishing regulations, Natural Resources and Endangered Species Act regulations, and is the appointing authority for the director of MassWildlife.
    [Show full text]