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Triple , Ophthalmic , , with or (nee-oh-mye-sin, pol-ee-mix-in, bass-i-tray-sin, gram-i-sye-din) Category: Broad-Spectrum Antimicrobial Combination Ophthalmic Agents Other Names for this Medication: Neosporin® Ophthalmic Ointment, Neo-Polycin® Ophthalmic Ointment, Trioptic-P® Common Dosage Forms: Veterinary: Bacitracin 400 units/neomycin 3.5 mg/ 10,000 units per gram ointment in 3.5 g tubes. Human: Polymyxin 10,000 Units/neomycin 1.75 mg/gramicidin 0.025 mg per mL ophthalmic solution; Bacitracin 400 units/neomycin 3.5 mg/polymyxin B 10,000 units per gram ophthalmic ointment 3.5 g tube.

This information sheet does not contain all available information for this medication. It is to help answer commonly asked questions and help you give the medication safely and eff ectively to your animal. If you have other questions or need more information about this medication, contact your veterinarian or pharmacist.

When should this medication not be used or be used very Key Information carefully? X Cats may have a severe allergic reaction to the neomycin No drug is 100% safe in all patients, but your veterinarian will or polymyxin parts of this medication. discuss with you any specific concerns about using this drug in your X Use proper administration techniques to avoid animal. contamination of the medication. Keep cap tightly closed This drug SHOULD NOT be used in patients: when not in use. XXThat are allergic to it or drugs like it. X Wait 5 minutes aft er applying this medication before This drug should be used in: applying any other medications to the eye. WITH CAUTION XXAnimals that are pregnant or nursing. X Store at room temperature, away from moisture and sunlight; do not freeze. Do not use if the color changes, or XXCats, as they may be severely allergic to the neomycin or it becomes cloudy. polymyxin B in this drug. If your animal matches any of these, talk to your veterinarian about the potential risks of using the medication versus the benefits that How is this medication useful? it might have. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans and animals. It is commonly used to treat What are the side eff ects of this medication? of the eyes, eyelids, and tissues surrounding the eyeball Side e ects that usually are not serious include: (conjunctiva) that are sensitive to the in it. Your veteri- XXMild burning, stinging, irritation, or redness of the eyes. narian may use this to treat an eye until the specific cause If any of these are severe, worsen, or continue to be a problem, is known and may switch your animal to another individual antibi- contact your veterinarian. otic eye medication. You and your veterinarian can discuss why this drug is the most appropriate choice. Side e ects that may be serious or indicate a serious problem: XXDiff iculty breathing or swelling of the throat (seen as noisy What should I tell my veterinarian to see if this medication can breathing) may indicate a severe allergic reaction to this drug. be safely given? If you see any of these, contact your veterinarian immediately. Many things might aff ect how well this drug will work in your animal. Be sure to discuss the following with your veterinarian so If my pet gets too much of this medication (an overdose), what together you can make the best treatment decisions. should I do? XXOther drugs can interact with this medication, so be sure to tell When used as an eye medication, overdoses are not likely. But side your veterinarian and pharmacist what medications (including eff ects or toxic eff ects could occur if your animal eats the medica- other eye medications, vitamins, supplements, or herbal tion. If this happens, contact your veterinarian or an animal poison therapies) you give your animal, including the amount and time control center for further advice. Animal poison control centers that you give each. are open 24 hours a day include ASPCA Animal Poison Control XXTell your veterinarian about any conditions or diseases your pet Center (888-426-4435) and Pet Poison HELPLINE (855-764-7661); a may have now or has had in the past. consultation fee may be charged for these services. XXIf your animal has been treated for the same disease or condition in the past, tell your veterinarian about the treatment and how well it did or didn’t work. XXIf your animal is pregnant or nursing, talk to your veterinarian about the risks of using this drug. XXTell your veterinarian and pharmacist about any medication side eff ects (including allergic reactions, lack of appetite, diarrhea, itching, hair loss) your pet has developed in the past.

©2017 PharmaVet, Inc. ALL RIGHTS RESERVED. Plumb’s® Veterinary Medication Guides have not been reviewed by FDA Center for Veterinary Medicine. How should this medication be given? How should I store this medication? For this medication to work, give it exactly as your veterinarian has XXStore this medication in the original prescription bottle or an prescribed. It’s a good idea to always check the prescription label to approved dosage reminder container at room temperature and be sure you are giving the drug correctly. protected from light. XXAdminister this drug to your animal’s eye in the exact amount XXIf your veterinarian or pharmacist has made (compounded) that your veterinarian has prescribed. a special formulation for your animal, follow the storage XXWash your hands before administering this medication. recommendations and expiration date for the product. XX XXDo not touch the dropper tip or allow it to touch your animal’s Keep away from children and other animals. eye or any other surface to prevent contamination. Can handling this medication be hazardous to me, my family, or XX If any residue is left on your animal’s face after giving the eye other pets? drops, gently wipe it off with a damp cloth or tissue. There are no specific precautions required when handling this med- XXIf you are administering more than one eye medication to your ication unless you are allergic to it or other drugs like it. Wash your animal, wait 5 minutes between each medication before giving hands after handling any medication. the next one. Use eye drops before eye ointments to allow the drops to absorb into the eye. How should I dispose of this medication if I don’t use it all? XXIf you are using this medication as an eye solution for your horse, XXDo not flush this medication down the toilet or wash it down the your veterinarian may have implanted a special eye catheter sink. If a community drug “take-back” program is available, use (subpalpebral lavage or SPL catheter). Use this catheter exactly this option. If there is no take-back program, mix the drug with as your veterinarian has prescribed and only use air to flush the coffee grounds or cat litter (to make it undesirable to children medications into the eye after injecting into the catheter. and animals and unrecognizable to people who might go through XXIf you are having difficulty applying the medication or your your trash), place the mixture in a sealable plastic bag to keep it animal does not accept the treatment, ask your veterinarian or from leaking out, and throw the bag out with the regular trash. pharmacist for tips to help with administration and reducing the XXDo not save left over medication for future use or give it to others stress of medication time. to use. XXThis medication can be given for various lengths of time. Be sure you understand how long your veterinarian wants you What other information is important for this medication? to continue giving this medication. Prescription refills may be XXUse of this drug may not be allowed in certain animal necessary before the therapy will be complete. Before stopping competitions. Check rules and regulations before entering this medication, talk to your veterinarian, as there may be your animal in a competition while this medication is being important reasons to continue its use. administered.

What should I do if I miss giving a dose of this medication? If you have any other questions or concerns about this medica- tion, contact your veterinarian or pharmacist. If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed, and give it at the next scheduled time. After that, return to the regular dosing schedule. Do not double-up or give extra doses.

©2017 PharmaVet, Inc. ALL RIGHTS RESERVED. Plumb’s® Veterinary Medication Guides have not been reviewed by FDA Center for Veterinary Medicine. Triple Antibiotic with , Ophthalmic Neomycin, Polymyxin, Bacitracin (nee-oh-mye-sin, pol-ee-mix-in, bas-i-tray-sin with hye-dro-kort-uh-sown) Category: Topical Antibiotic & Antiinflammatory Agent Other Names for this Medication: Trioptic-S®, Vetropolycin S® Common Dosage Forms: Veterinary: Bacitracin 400 units/neomycin 3.5 mg/polymyxin B 10,000 units with hydrocortisone 10 mg per g ointment. Human: Bacitracin 400 Units/neomycin 1.75 mg/polymyxin 10,000 Units with hydrocortisone 10 mg per g ointment.

This information sheet does not contain all available information for this medication. It is to help answer commonly asked questions and help you give the medication safely and eff ectively to your animal. If you have other questions or need more information about this medication, contact your veterinarian or pharmacist.

When should this medication not be used or be used very care- Key Information fully? X Do not use in animals with an eye ulcer or cat that may No drug is 100% safe in all patients, but your veterinarian will discuss have a herpesvirus infection. Not to be used in birds. with you any specific concerns about using this drug in your animal. X Cats may have a severe allergic reaction to the neomycin This drug SHOULD NOT be used in patients: or polymyxin parts of this medication; use with caution. XXThat are allergic to it or drugs like it. X Use proper administration techniques to avoid XXBirds as they are very sensitive to . contamination of the medication. Keep cap tightly closed when not in use. XXThat are suspected of having eye infections caused by viruses (eg, herpes) or fungus. X Wait 5 minutes aft er applying this medication before applying any other medications to the eye. XXAnimals that have an eye ulcer. X Store at room temperature away from moisture and This drug should be used WITH CAUTION in: sunlight; do not freeze. Do not use if the color changes or XXAnimals that are pregnant or nursing. the medicine becomes cloudy. XXThat are diabetic. XXThat have glaucoma. XXCats, as they may be severely allergic to the neomycin or How is this medication useful? polymyxin B in this drug. Triple antibiotic with hydrocortisone ophthalmic medication is commonly used to treat inflammation and infections of the eyes. If your animal matches any of these conditions, talk to your veteri- narian about the potential risks of using the medication versus the The FDA (U.S. Food & Drug Administration) has approved this drug benefits. for use in humans and animals. It is It may also be used to treat eye conditions caused by allergies. You and your veterinarian can What are the side eff ects of this medication? discuss why this drug is the most appropriate choice. Side e ects that usually are not serious include: What should I tell my veterinarian to see if this medication can XXMild burning, stinging, irritation, or redness of the eyes. be safely given? XXDrooping of the eyelid. Many things might aff ect how well this drug will work in your If any of these signs are severe, worsen, or continue to be a prob- animal. Be sure to discuss the following with your veterinarian so lem, contact your veterinarian. together you can make the best treatment decisions. Side e ects that may be serious or indicate a serious problem: XXOther drugs can interact with this medication, so be sure to tell XXDiff iculty breathing or swelling of the throat may indicate a your veterinarian and pharmacist what medications (including severe allergic reaction to this drug. other eye medications, vitamins, supplements, or herbal XX therapies) you give your animal, including the amount and time Signs of an eye infection (eg, worsening of pain, discharge from you give each. the eye, squinting). XXFailure of eye injuries to heal. XXTell your veterinarian about any conditions or diseases your pet may have now or has had in the past. XXChanges in blood or urine sugar in diabetic animals. XXIf your animal has been treated for the same disease or condition If you see any of these signs, contact your veterinarian immediately. in the past, tell your veterinarian about the treatment and how well it did or didn’t work. If my pet gets too much of this medication (an overdose), what should I do? XXIf your animal is pregnant or nursing, talk to your veterinarian about the risks of using this drug. When used as an eye medication overdoses are unlikely, but side eff ects or toxic eff ects could occur if your animal eats the medica- XXTell your veterinarian and pharmacist about any medication side tion. If this happens contact your veterinarian or an animal poison eff ects (including allergic reactions, lack of appetite, diarrhea, control center for further advice. Animal poison control centers that itching, hair loss) your pet has developed in the past. are open 24 hours a day include ASPCA Animal Poison Control Center (888-426-4435) and Pet Poison HELPLINE (855-764-7661); a consultation fee may be charged for these services.

©2017 PharmaVet, Inc. ALL RIGHTS RESERVED. Plumb’s® Veterinary Medication Guides have not been reviewed by FDA Center for Veterinary Medicine. How should this medication be given? How should I store this medication? For this medication to work, give it exactly as your veterinarian has XXStore this medication in the original prescription bottle at room prescribed. It’s a good idea to always check the prescription label to temperature and protected from light. be sure you are giving the drug correctly. XXIf your veterinarian or pharmacist has made (compounded) XXAdminister this drug to your animal’s eye in the exact amount a special formulation for your animal, follow the storage that your veterinarian has prescribed. recommendations and expiration date for the product. XXWash your hands before administering this medication. XXKeep away from children and other animals. XXShake liquid forms of this medication well before applying. Can handling this medication be hazardous to me, my family, or XX Do not touch the dropper tip or allow it to touch your animal’s other pets? eye or any other surface to prevent contamination. There are no specific precautions required when handling this med- XXIf any residue is left on your animal’s face after giving the eye ication unless you are allergic to it or other drugs like it. Wash your drops, gently wipe it off with a damp cloth or tissue. hands after handling any medication. XXIf you are administering more than one eye medication to your animal, wait 5 minutes between each medication before giving How should I dispose of this medication if I don’t use it all? the next one. Use eye drops before eye ointments to allow the XXDo not flush this medication down the toilet or wash it down the drops to absorb into the eye. sink. If a community drug “take-back” program is available, use XXIf you are using this medication as an eye solution for your horse, this option. If there is no take-back program, mix the drug with your veterinarian may have implanted a special eye catheter coffee grounds or cat litter (to make it undesirable to children (subpalpebral lavage or SPL catheter). Use this catheter exactly and animals and unrecognizable to people who might go through as your veterinarian has prescribed and only use air to flush the your trash), place the mixture in a sealable plastic bag to keep it medications to the eye after injecting into the catheter. from leaking out, and throw the bag out with the regular trash. XX XXIf you are having difficulty applying the medication or your Do not save leftover medication for future use or give it to others animal does not accept the treatment, contact your veterinarian to use. or pharmacist for tips to help with administration and reducing the stress of medication time. What other information is important for this medication? XXUse of this drug may not be allowed in certain animal XXThis medication can be given for various lengths of time. Be competitions. Check rules and regulations before entering sure you understand how long your veterinarian wants you your animal in a competition while this medication is being to continue giving this medication. Prescription refills may be administered. necessary before the therapy will be complete. Before stopping this medication, talk to your veterinarian, as there may be If you have any other questions or concerns about this medica- important reasons to continue its use. tion, contact your veterinarian or pharmacist. What should I do if I miss giving a dose of this medication? If you miss a dose, give it when you remember, but if it is close to the time for the next dose, skip the dose you missed and give it at the next scheduled time. After that, return to the regular dosing schedule. Do not double-up or give extra doses.

©2017 PharmaVet, Inc. ALL RIGHTS RESERVED. Plumb’s® Veterinary Medication Guides have not been reviewed by FDA Center for Veterinary Medicine.