PRENATAL DIAGNOSIS OF TETRALOGY OF FALLOT Hamdi A, Jaziri D, Cherni A, Chajia A, Boudaya F, Chelli D Maternity and Neonatal Center of Tunisia

INTRODUCTION: Tetralogy of Fallot (TOF) is seen in the long-axis view, and right ventricular a congenital heart defect classically described like hypertrophy. Other findings such as hydrops fetalis a four anatomical heart abnormalities. It is the most or polyhydramnios may also be helpful especially frequent cyanotic heart defect, and the most in the case of dysplastic pulmonary valves. The common cause of blue baby syndrome due to right demonstration of a normal aortic root would render to left shunt. the presence of TOF unlikely (1).

OBJECTIVE: Determine the sensitivity and specificity of ultrasonography in the diagnosis of 100% Tetralogy of Fallot, through ultrasound 80% 60% examination. 40% 20% MATERIALS AND METHODS: Retrospective 0% study conducted at the Maternity and Neonatal Center of Tunis in the Embryo - Foetopathology Department, of all cases of Tetralogy of Fallot, over a period of 2 years, from January 2011 to December 2012.

CONCLUSION: The Tetralogy of Fallot is the most common congenital cyanotic heart disease. The antenatal diagnosis can lead to look for other associated abnormalities or chromosomal aberrations and allows us to determine a therapeutic strategy.

RESULTS: Ninety-five cases of congenital heart TOF TOF Total defects, which represents a frequency of 5.73%, were recorded in 1,482 ultrasound examinations. (+) (-)

Out of the 85 detected heart defects, 9 were Tetralogy of Fallot, which represents a frequency of 10%. The sensitivity of ultrasound in the detection of TOF was 55.55 % and specificity was Echo (+) 5 0 5 100%. Ultrasound has a good positive predictive value in the detection of TOF of 100%. Its negative predictive value was 95%. In our series, the combination of TOF and extracardiac malformations were noticed in 78% of cases, Echo (-) 4 76 80 mainly craniofacial anomalies in 45% of cases.

DISCUSSION: Prenatal sonographic findings suggestive of TOF are summarized as follows: a Total 9 76 85 large aortic root, which is the most common prenatal sonographic finding, a small pulmonary artery or stenosis of the right ventricular outflow Tetralogy of Fallot in the fetus: findings at targeted tract, a ventricular septal defect in the outlet portion sonography. Yoo SJ1 Ultrasound Obstet Gynecol. 1999 of the septum, an overriding aorta, which is best Jul;14(1):29-37