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Generated by SRI International Pathway Tools Version 25.0, Authors S Authors: Pallavi Subhraveti Ron Caspi Peter Midford Peter D Karp An online version of this diagram is available at BioCyc.org. Biosynthetic pathways are positioned in the left of the cytoplasm, degradative pathways on the right, and reactions not assigned to any pathway are in the far right of the cytoplasm. Transporters and membrane proteins are shown on the membrane. Ingrid Keseler Periplasmic (where appropriate) and extracellular reactions and proteins may also be shown. Pathways are colored according to their cellular function. Gcf_000007205Cyc: Chlamydia pneumoniae TW-183 Cellular Overview Connections between pathways are omitted for legibility. Anamika Kothari lipid II (meso diaminopimelate a nucleoside phosphate containing) triphosphate RS00955 RS00740 RS00560 RS05595 RS05185 RS01915 RS01895 RS01865 RS03045 RS02815 RS04245 RS04280 RS05145 RS02970 RS02755 SctV RS04155 RS03490 RS02865 RS05270 RS04090 RS01435 RS02585 RS03405 RS01225 RS05540 RS01155 RS04950 RS01135 RS01115 RS01125 RS01140 RS01145 RS01160 RS01165 RS01235 RS01355 RS01430 RS05310 RS01480 RS01500 SecG RS01580 RS02720 FtsW RS01745 RS05245 RS04240 RS01800 RS01840 RS03050 RS05020 RS03070 RS02010 RS04850 RS00470 RS00640 RS00860 RS01025 RS03135 RS03480 lipid II (meso diaminopimelate a nucleoside phosphate containing) triphosphate TolB RS01290 Nucleoside and Nucleotide Degradation glutaminyl-tRNA gln Aminoacyl-tRNA Charging Carbohydrate Biosynthesis di-trans,octa-cis UDP-N-acetyl- a nascent peptidoglycan a peptidoglycan a CDP- a [bis(guanylyl DNA with adenine:7,8- biosynthesis via transamidation Macromolecule Modification UTP and CTP dephosphorylation I sn-glycerol a nucleoside -undecaprenyl α-D-muramoyl- with (L-alanyl-γ-D- with (L-alanyl-γ-D- molybdopterin) dihydro-8- RNA ala a protein RS04785 RS04100 glycolysis IV Glycolysis 3-phosphate diacylglycerol ATP cys triphosphate UDP-N-acetyl- ATP ATP roseoflavin dGDP phosphatephospho-N- L-alanyl-γ-D- glutamyl-meso-2,6- glutamyl-meso-2,6- a tRNA precursor cofactor oxoguanine mismatch α-D-muramate RNA UDP-N-acetyl-D- UTP CTP 5'-phosphate ATP- ribonucleoside- glu CMP-3-deoxy-D- glycogen biosynthesis I (from ADP-D-Glucose) tRNA-uridine 2-thiolation acetylmuramoyl- glutamyl-meso-2,6- diaminopimeloyl- diaminopimeloyl-D- chaperone]- glucosamine biosynthesis I lipoprotein posttranslational modification dependent Clp diphosphate manno-octulosonate and selenation (bacteria) F6P CTP synthase: pentapeptide- diaminopimeloyl- D-alanyl-D-alanine) alanine) tetrapeptide CDP-diacylglycerol-- L-cysteine A/G-specific DNA- protease: clpX D-glucopyranose bifunctional UDP- reductase: biosynthesis D-glucopyranose 6-phosphate CPB_RS01200 transferase: D-alanyl-D-alanine pentapeptide glycerol-3-phosphate 3- CCA tRNA adenine directed RNA polynucleotide bifunctional CPB_RS04365 6-phosphate a [prolipoprotein]- N-acetylmuramate- CPB_RS05085 RS04520 RS03470 glucose-6- D-ribulose cys diphosphate--fructose- CPB_RS04660 phosphatidyltransferase: nucleotidyltransferase: glycosylase: polymerase: adenylyltransferase riboflavin phospho- L-cysteine UDP cysteine -L-alanine ligase/ ATP-dependent CPB_RS05090 phosphate 5-phosphate 6-phosphate 1- CTP pgsA CPB_RS04355 mutY rpoB rpoC PcnB: pcnB kinase/FAD gln an L-glutamyl- sugar mutase: prolipoprotein penicillin-binding desulfurase: D-alanine--D- Clp protease isomerase: cysteine phosphotransferase: synthetase: GDP [tRNA Gln ] diacylglyceryl protein 2: CPB_RS03530 DNA-directed alanine ligase: proteolytic CPB_RS05300 aldehydo-D- CPB_RS00275 CPB_RS00815 1-(3-sn- a tRNA CPB_RS01640 Asp-tRNA(Asn) desulfurase: transferase: CPB_RS02140 CMP RNA polymerase CPB_RS04685 subunit: Asp-tRNA(Asn) arabinose 5- α-D-glucopyranose [+ 2 isozymes] an apurinic site RNA RS04125 /Glu-tRNA(Gln) F6P CPB_RS04445 diphosphate--fructose- UMP phosphatidyl) containing a subunit alpha: CPB_RS02635 phosphate 1-phosphate CPB_RS01595 CDP undecaprenyldiphospho- UMP adenine within DNA amidotransferase: /Glu-tRNA(Gln) [+ 2 isozymes] a [prolipoprotein]- 6-phosphate 1- -sn-glycerol 3' CCA end CPB_RS03205 roseoflavin glutamine-- an [L-cysteine 5'/3'- N-acetylmuramoyl-L- a nascent peptidoglycan a [bis(guanylyl UDP-N-acetyl- a peptide gatC gatA gatB amidotransferase: glucose-1-phosphate S-1,2-diacyl-sn- phosphotransferase: γ 3-phosphate adenine fructose-6- nucleotidase alanyl- -D-glutamyl-meso with D,D cross-links D-ala ala molybdopterin) α-D-muramoyl- gatC gatA gatB adenylyltransferase: desulfurase]-S- glyceryl-L-cysteine CPB_RS01055 dinucleotide [+ 2 isozymes] phosphate SurE: surE -2,6-diaminopimeloyl- (meso-diaminopimelate cofactor L-alanine a 5-phosphooxy- D-arabinofuranose glgC sulfanyl-L-cysteine β RNA TarP transaminase -D-fructose 1,6- CMP D-alanyl-D-alanine containing) chaperone]-S- ammonium L-glutamyl- 5-phosphate lipoprotein uridine Gln α α bisphosphate [tRNA ] (isomerizing) a (1->4)- -D-glucan ADP- -D-glucose 5'/3'- sulfanyl-L-cysteine 3-deoxy-8- signal peptidase: : glmS nucleotidase phosphooctulonate glycogen a [TusA sulfur- CPB_RS02710 class I fructose- Asp-tRNA(Asn) D-glucosamine SurE: surE UDP-N-acetyl-α-D-muramoyl- a Chi-site containing a RecA DNA an N-terminal- synthase: kdsA synthase carrier protein]-S- bisphosphate a 2'-deoxyribonucleoside phosphoenol a supercoiled CopD /Glu-tRNA(Gln) 34 H O oxaloacetate H O 6-phosphate an (S-diacyl-sn- a 5,10-gly a uridine L-alanyl-γ-D-glutamyl- double stranded recombination diphosphate 2 2 L-methionyl-L- GlgA: glgA sulfanyl-L-cysteine a lipoprotein aldolase: cytidine D-alanyl-D-alanine 5'-triphosphate [DNA] ITP GTP dGDP pyruvate duplex DNA ATP dADP amidotransferase: glyceryl)-L-cysteinyl- methylenetetrahydrofolate in tRNA meso-2,6-diaminopimelate DNA with a blunt end and repair protein seryl-[protein] UvrD-helicase phosphoglucosamine KDO-8P α signal peptide CPB_RS01445 biotin gatC gatA gatB tRNA charging a (1->4)- -D-glucan [apolipoprotein] domain- ribonucleoside- mutase: CPB_RS05005 UDP-α-D-glucose apolipoprotein N- adenosine DNA polymerase RdgB/HAM1 family containing diphosphate α-D-glucosamine 1,4-alpha-glucan biosynthesis a [TusD sulfur- tRNA uridine-5- UDP-N- exodeoxyribonuclease ribosome methionyl an L-glutaminyl- acyltransferase: lnt triose-phosphate nucleotides III subunit non-canonical phosphoenolpyruvate protein: biotin-- reductase: RS00100 phe Phe 1-phosphate branching carrier protein]-S- carboxymethylaminomethyl(34) acetylmuramoyl- V: CPB_RS03800 recB biogenesis pyruvate aminopeptidase: [tRNA Gln ] a tRNA D-glucopyranose isomerase: degradation III gamma/tau: dnaX purine NTP carboxykinase (GTP) CPB_RS03985 [acetyl-CoA- CPB_RS05085 protein GlgB: glgB sulfanyl-L-cysteine an N-acyl-(S-diacyl- synthesis GTPase MnmE: mnmE tripeptide--D-alanyl- exodeoxyribonuclease GTPase kinase: pyk CPB_RS05215 met RS01440 met α 6-phosphate a peptide : CPB_RS04390 CPB_RS05090 -Kdo phospho- sn-glyceryl)-L- CPB_RS05495 D-glyceraldehyde D- alanine ligase: V subunit alpha: recD [+ 4 isozymes] pyrophosphatase: replicative carboxylase] a glycogen DHAP tRNA uridine-5- Der: der sugar mutase: cysteinyl-[lipoprotein] 3-phosphate AMP CPB_RS04655 rdgB DNA ligase: ADP phenylalanine- α 3-deoxy-manno- carboxymethylaminomethyl(34) [+ 2 isozymes] an N-terminal N-acetyl- -D- CPB_RS00275 AMP inorganic helicase: CPB_RS04465 RS04395 Arg -tRNA ligase asp ser Ala octulosonate α-D-glucopyranose synthesis enzyme MnmG: mnmG a double stranded DNA pyruvate met L-seryl-[protein] ala RS02715 ala arg a tRNA tRNA asp ser a tRNA a tRNA ala glucosamine a [TusE sulfur nucleosidase: [DNA] phosphoenolpyruvate elongator type I α pyrophosphatase: dGTP dnaB + + subunit beta: cytidylyltransferase: 1-phosphate UDP-N-acetyl- -D-muramoyl-L- with a RecA protein IDP + H RS04055 H val a tRNA Val ile a tRNA Ile met initiator tRNA Met met leu a tRNA Leu tyr a tRNA Tyr pro a tRNA Pro glu a tRNA glu his a tRNA His trp a tRNA Trp thr a tRNA Thr lys a tRNA Lys cys a tRNA Cys gly a tRNA Gly 1-phosphate 34 carrier protein]-S CPB_RS04625 H a single tRNA Met CPB_RS03030 kdsB a uridine in tRNA glyceraldehyde- alanyl-γ-D-glutamyl-meso-2,6- loaded 3' overhang CPB_RS04750 GDP phosphate biotinyl-5'- UDP-GlcNAc UDP-glucose -sulfanylcysteine adenine a 5-carboxymethylaminomethyluridine 34 stranded DNA Asn Gln 3-phosphate a 7,8-dihydrofolate arginine- phenylalanine- aspartate- serine- alanine- asn tRNA gln a tRNA diaminopimeloyl-D-alanyl-D-alanine adenylate pyrophosphorylase: CMP-Kdo pyrophosphorylase: dehydrogenase: in tRNA ala RS04515 ala tRNA 2- RS05190 valine-- isoleucine-- methionine-- methionine-- leucine-- tyrosine-- proline-- glutamate-- -tRNA -tRNA ligase -tRNA histidine-- tryptophan- threonine- -tRNA -tRNA lysine- cysteine-- glycine-- CPB_RS03870 CPB_RS04415 phosphoglycerate + gap H + V-type ATP + tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: tRNA ligase: ligase: subunit ligase: tRNA ligase: -tRNA -tRNA ligase: ligase: -tRNA tRNA ligase: tRNA ligase: thiouridine(34) kinase: phosphate H H UDP-N-acetyl- UDP-α-D-glucose synthase CPB_RS00475 CPB_RS00550 CPB_RS00615 CPB_RS00615 CPB_RS00770 CPB_RS01835 CPB_RS02535 CPB_RS02845 argS alpha: pheS aspS CPB_RS03395 ligase: trpS ligase: thrS serS alaS ligase: lysS CPB_RS04820 CPB_RS04890 α-D-glucosamine synthase CPB_RS03475 3-phospho- MnmA: mnmA D-glycerate tyr RS05015 tyr 13-DPG S-methyl-5'-thioadenosine an L-methionyl- 34 a 2'- an N-terminal- an L-valyl- an L-isoleucyl- an L-methionyl- an L-leucyl- an L-tyrosyl- an L-prolyl- an L-glutamyl- an L-arginyl- an L-phenylalanyl- an L-aspartyl- an L-histidyl- an L-tryptophanyl- an L-threonyl- an L-seryl- an L-alanyl- an L-lysyl- an L-cysteinyl-
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