bioRxiv preprint doi: https://doi.org/10.1101/2020.01.23.904417; this version posted January 24, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. The defining genomic and predicted metabolic features of the Acetobacterium genus Daniel E. Ross1,2*, Christopher W. Marshall3, Djuna Gulliver1, Harold D. May4, and R. Sean Norman5 1National Energy Technology Laboratory, 626 Cochrans Mill Road, P.O. Box 10940, Pittsburgh, PA 15236-0940, USA. 2Leidos Research Support Team, 626 Cochrans Mill Road, P.O. Box 10940, Pittsburgh, PA 15236-0940, USA. 3Department of Biological Sciences, Marquette University, Milwaukee, WI, USA. 4Department of Microbiology & Immunology, Hollings Marine Laboratory, Medical University of South Carolina, Charleston, SC, USA. 5Department of Environmental Health Sciences, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA. Correspondence Daniel E. Ross
[email protected] bioRxiv preprint doi: https://doi.org/10.1101/2020.01.23.904417; this version posted January 24, 2020. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC-ND 4.0 International license. Abstract Acetogens are anaerobic bacteria capable of fixing CO2 or CO to produce acetyl-CoA and ultimately acetate using the Wood-Ljungdahl pathway (WLP). This autotrophic metabolism plays a major role in the global carbon cycle.