sign in sign up
<<
Home , 40S ribosomal protein S3, 60S ribosomal protein L4, 60S ribosomal protein L7, Diacylglycerol kinase, YWHAB

Table 6. β-arrestin 2-interacting under stimulated (+) condition

IPI accession Swiss-Prot Number of accession name experiments number number symbol detected Signal transduction Adaptor proteins IPI00027355 P32121 ARRB2 β-arrestin 2 6 IPI00293857 P49407 ARRB1 β-arrestin 1 6 IPI00021353 P10523 SAG S-arrestin (Retinal S-antigen) (48 kDa protein) (S-AG) (Rod photoreceptor arrestin) 2 IPI00216318 P31946 YWHAB 14-3-3 β/α (14-3-3 protein beta/alpha) (Protein C inhibitor protein 1) (KCIP-1) (Protein 1054) 2 IPI00220642 P61981 YWHAG 14-3-3 γ (14-3-3 protein gamma) ( C inhibitor protein 1) (KCIP-1) 2

Protein IPI00027251 Q15208 STK38 STK38 (Serine/threonine-protein kinase 38) (NDR1 protein kinase) (Nuclear Dbf2-related kinase 1) 2 SCY1-like 2 (SCY1-like 2 protein) (coated vesicle-associated kinase of 104 kDa) (Eukaryotic protein IPI00396218 Q6P3W7 SCYL2 2 kinase family protein) (CDNA FLJ10074 fis, clone HEMBA1001744, weakly similar to SCY1 PROTEIN) IPI00013835 Q13574 DGKZ DGK ζ (Diacylglycerol kinase zeta) ( kinase zeta) (DGK-zeta) (DAG kinase zeta) 2 DGK ε (Diacylglycerol kinase epsilon) (Diglyceride kinase epsilon) (DGK-epsilon) (DAG kinase IPI00003293 P52429 DGKE 2 epsilon) Casein kinase II (casein kinase II alpha 1 subunit) (protein kinase CK2) (CK2 catalytic subunit alpha) IPI00472911 P68400 CSNK2A1 2 (casein kinase II alpha subunit) (casein kinase II-alpha subunit) (Casein kinase II alpha 1 subunit isoform b) ERK-2 (-activated protein kinase 1) (Extracellular signal-regulated kinase 2) (Mitogen-activated IPI00003479 P28482 MAPK1 2 protein kinase 2) (MAP kinase 2) (MAPK 2) (p42-MAPK) (ERT1) IPI00172636 Q8N553 CAMK2D CaM kinase II delta (Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta) 2 Cell division cycle 2-like protein kinase 5 (CDC2- related protein kinase 5) (Cholinesterase-related cell IPI00029162 Q14004 CDC2L5 2 division controller) IPI00023503 Q00526 CDK3 Cell division protein kinase 3 2 Cell division protein kinase 7 (CDK- activating kinase) (CAK) (TFIIH basal transcription factor complex IPI00000685 P50613 CDK7 2 kinase subunit) (39 kDa protein kinase) (P39 Mo15) (STK1) (CAK1) IPI00167096 Q8N752 CSNK1A1L CK1 (Casein kinase I isoform alpha-like) (CKI-alpha-like) 2 IPI00163851 Q9P2K8 EIF2AK4 GCN2 eIF2α kinase (Eukaryotic 2-alpha kinase 4) (GCN2-like protein) 2 IPI00001814 Q9P286 PAK7 PAK-7 (Serine/threonine-protein kinase PAK 7) (p21-activated kinase 7) (PAK-5) 2 IPI00012318 Q13233 MAP3K1 MEKK 1 (Mitogen-activated protein kinase kinase kinase 1) (MAPK/ERK kinase kinase 1) (MEK kinase 1) 2 NIK (Mitogen-activated protein kinase kinase kinase 14) (NF- kappa beta-inducing kinase) IPI00016099 Q99558 MAP3K14 2 (Serine/threonine-protein kinase NIK) (HsNIK) IPI00025830 P30291 WEE1 Wee1A kinase (Wee1-like protein kinase) (WEE1hu) 2 IPI00007811 P11802 CDK4 CDK4 (Cell division protein kinase 4) (Cyclin-dependent kinase 4) (PSK-J3) 2 PRP4 kinase (Serine/threonine-protein kinase PRP4 homolog) (PRP4 pre- mRNA-processing factor 4 IPI00013721 Q13523 PRPF4B 3 homolog) PI3-K-C2α (-4-phosphate 3-kinase C2 domain-containing alpha polypeptide) IPI00002580 O00443 PIK3C2A 2 (Phosphoinositide 3-Kinase-C2-alpha) (PtdIns-3-kinase C2 alpha) (PI3K-C2alpha) serine/threonine-protein kinase SRPK2 (Serine/arginine- rich protein-specific kinase 2) (SR-protein-specific IPI00333420 P78362 SRPK2 2 kinase 2) (SFRS protein kinase 2) TAK1 (Mitogen-activated protein kinase kinase kinase 7) (Transforming growth factor-beta-activated kinase IPI00218566 O43318 MAP3K7 2 1) (TGF-beta-activated kinase 1). IPI00004237 P46019 PHKA2 kinase alpha L subunit (Phosphorylase b kinase regulatory subunit alpha, liver isoform) 2

Phosphatases IPI00020950 P35813 PPM1A PP2Cα (Protein phosphatase 2C isoform alpha) (PP2C-alpha) (IA) (Protein phosphatase 1A) 4 IPI00026612 O75688 PPM1B PP2Cβ (Protein phosphatase 2C isoform beta) (PP2C-beta) 4 PP2A, subunit A, PR65-α (Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha IPI00554737 P30153 PPP2R1A isoform) (PP2A, subunit A, PR65-alpha isoform) (PP2A, subunit A, R1-alpha isoform) (Medium tumor 2 antigen-associated 61 kDa protein) Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin IPI00183002 O14974 PPP1R12A 2 phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)

Trafficking IPI00216393 P09496 CLTA Clathrin light chain A 2 IPI00216472 P09497 CLTB Clathrin light chain B 2 AP-2 α1 (AP-2 complex subunit alpha-1) (Adapter-related protein complex 2 alpha- 1 subunit) (Alpha- IPI00304577 O95782 AP2A1 adaptin A) (Adaptor protein complex AP-2 alpha-1 subunit) (Clathrin assembly protein complex 2 alpha-A 2 large chain) (100 kDa coated vesicle protein A) (Plasma membrane adaptor HA2/AP2 adaptin alpha A AP-2 β1 (AP-2 complex subunit beta-1) (Adapter-related protein complex 2 beta-1 subunit) (Beta-adaptin) IPI00784156 P63010 AP2B1 (Plasma membrane adaptor HA2/AP2 adaptin beta subunit) (Clathrin assembly protein complex 2 beta 2 large chain) (AP105B) Gaf-1 (Rab11 family-interacting protein 5) (Rab11-FIP5) (Rab11-interacting protein Rip11) (Gamma- IPI00022033 Q9BXF6 RAB11FIP5 2 SNAP-associated factor 1) (Phosphoprotein pp75) VPS35 (Vesicle protein sorting 35) (Vacuolar protein sorting-associated protein 35) (hVPS35) (Maternal- IPI00018931 Q96QK1 VPS35 2 embryonic 3) IPI00018452 Q99829 CPNE1 Copine-1 (Copine I) 2 AP-2 α2 (AP-2 complex subunit alpha-2) (Adapter-related protein complex 2 alpha- 2 subunit) (Alpha- adaptin C) (Adaptor protein complex AP-2 alpha-2 subunit) (Clathrin assembly protein complex 2 alpha-C IPI00016621 O94973 AP2A2 2 large chain) (100 kDa coated vesicle protein C) (Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit) (Huntingtin-interacting protein HYPJ). IPI00005793 Q13367 AP3B2 AP-3 complex subunit beta-2 2 IPI00477270 Q5VYB9 LRP11 LRP11 protein (low density lipoprotein receptor-related protein 11) 2

G protein- and small GTPase-related α-Pix (Alpha-Pix) (Rho guanine nucleotide exchange factor 6) (Rac/Cdc42 guanine nucleotide exchange IPI00014256 Q15052 ARHGEF6 2 factor 6) (PAK-interacting exchange factor alpha) (COOL-2) IPI00294879 P46060 RANGAP1 RAN GTPase-activating protein 1 2 IPI00169307 Q8NI19 ARHGAP21 Rho GTPase activating protein 10 2 IPI00064767 Q68em7 ARHGAP17 Nadrin (Rho GTPase activating protein 17) 2 IPI00157442 O15085 ARHGEF11 Rho guanine nucleotide exchange factor 11 (PDZ-RhoGEF) 2 IPI00339353 Q9NZN5 ARHGEF12 Rho guanine nucleotide exchange factor 12 (Leukemia-associated RhoGEF) 2

Other signaling proteins IPI00075248 P62158 CALM1 Calmodulin (CaM) 2 Annexin II (Annexin A2) (Lipocortin II) (Calpactin I heavy chain) (Chromobindin-8) (p36) (Protein I) IPI00455315 P07355 ANXA2 2 (Placental anticoagulant protein IV) (PAP-IV) Mitogen-activated protein kinase kinase kinase 7-interacting protein 1 (TGF-beta-activated kinase 1-binding IPI00019459 Q15750 TAB1 2 protein 1) (TAK1-binding protein 1) I κ-B kinase α (Inhibitor of nuclear factor kappa-B kinase subunit alpha) (I kappa-B kinase alpha) (IkBKA) IPI00005104 O15111 IKKA (IKK-alpha) (IKK-A) (IkappaB kinase) (I-kappa-B kinase 1) (IKK1) (Conserved helix-loop- helix ubiquitous 2 kinase) (Nuclear factor NF-kappa-B inhibitor IPI00215948 P35221 CTNNA1 Catenin α-1 (Catenin alpha-1) (Cadherin-associated protein) (Alpha E-catenin) (NY- REN-13 antigen) 2 IPI00386765 Q08499 PDE4D PDE4D protein (cAMP-specific 3',5'-cyclic phosphodiesterase 4D) (DPDE3) (PDE43) 2 IPI00023461 P55196 MLLT4 Afadin (Protein AF-6) 3 Calgranulin B (Protein S100-A9) (S100 calcium-binding protein A9) (Migration inhibitory factor- IPI00027462 P06702 S100A9 2 related protein 14) (MRP-14) (P14) (Leukocyte L1 complex heavy chain) (Calprotectin L1H subunit) Nucleic acid binding DNA binding, chromatin structure and regualtion IPI00217469 Q02539 HIST1H1A Histone H1.1 (H1 histone family, member 1) 2 IPI00021924 Q92522 H1FX Histone H1x 2 IPI00216730 Q8IUE6 HIST2H2AB Histone H2A (Histone H2A type 2-B) 2 Ku70 (ATP-dependent DNA 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) ( IPI00644712 P12956 XRCC6 Ku autoantigen protein p70) (70 kDa subunit of Ku antigen) (Thyroid-lupus autoantigen) (TLAA) (CTC box- 2 binding factor 75 kDa subunit) (CTCBF) (CTC75) (DNA-repair protein XRCC6) IPI00289601 Q92769 HDAC2 HDAC2 (histone deacetylase 2) (hd2) 2 IPI00217465 P16403 HIST1H1C Histone H1.2 (Histone H1d) 5 IPI00219037 P16104 H2AFX H2AFX protein; Histone H2A.x (H2a/x) 2 RPA1 (Replication factor-A protein 1) (Replication protein A 70 kDa DNA-binding subunit) (RP-A) (RF-A) IPI00020127 P27694 RPA1 2 (Single-stranded DNA-binding protein) (p70).

Transcription factor and transcription regulatory protein Nopp 140 (Nucleolar phosphoprotein p130) (Nucleolar 130 kDa protein) (140 kDa nucleolar IPI00292387 Q14978 NOLC1 3 phosphoprotein) (Nucleolar and coiled-body phosphoprotein 1) IPI00298696 Q13428 TCOF1 Treacle (Treacher collins franceschetti syndrome 1) 6 JBP1 (Protein arginine N-methyltransferase 5) (Shk1 kinase-binding protein 1 homolog) (SKB1Hs) IPI00441473 O14744 PRMT5 3 (Jak-binding protein 1) (72 kDa ICln-binding protein) IPI00549248 P06748 NPM1 Nucleophosmin (NPM) (Nucleolar phosphoprotein B23) (Numatrin) (Nucleolar protein NO38) 2 IPI00029631 P84090 ERH ERH (Enhancer of rudimentary homolog) 2 TIF 1B (Transcription intermediary factor 1-beta) (TIF1-beta) (Tripartite motif-containing protein 28) IPI00438229 Q13263 TRIM28 (Nuclear corepressor KAP-1) (KRAB- associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) 3 (RING finger protein 96) YB-1 (Y-box transcription factor) (Nuclease sensitive element-binding protein 1) (Y-box-binding IPI00031812 P67809 YBX1 protein 1) (Y-box transcription factor) (CCAAT-binding transcription factor I subunit A) (CBF-A) 2 (Enhancer factor I subunit A) (EFI-A) (DNA-binding protein B) (DBPB) IPI00103090 Q8WVC0 LEO1 LEO1 (RNA -associated protein LEO1) (Replicative senescence down- regulated leo1-like 2 Tho4 (THO complex subunit 4) (Ally of AML-1 and LEF-1) (Transcriptional coactivator Aly/REF) IPI00328840 Q86V81 THOC4 2 (bZIP-enhancing factor BEF) ZNF265 (Zinc finger protein 265) (Zinc finger Ran-binding domain-containing protein 2) (Zinc finger, IPI00029400 O95218 ZNF265 6 splicing) Trap150 (Thyroid hormone receptor-associated protein 3) (Thyroid hormone receptor-associated IPI00104050 Q9Y2W1 THRAP3 6 protein complex 150 kDa component) IPI00013788 O43719 HTATSF1 TATSF1 (Tat-SF1) (HIV Tat-specific factor 1) 4 RPA194 (DNA-directed RNA polymerase I largest subunit) (EC 2.7.7.6) (RNA polymerase I 194 kDa IPI00031960 O95602 POLR1A 2 subunit) IPI00005179 O15160 POLR1C RPA40 (DNA-directed RNA polymerase I 40 kDa polypeptide) (RPA39) 2 IPI00291093 P19388 POLR2E RPB25 (DNA-directed RNA polymerase II 23 kDa polypeptide) (RPB25) (RPB5) (RPABC1) (XAP4) 2 STAT1 (signal transducer and activator of transcription 1) (Signal transducer and activator of transcription IPI00030781 P42224 STAT1 2 1-alpha/beta) (Transcription factor ISGF-3 components p91/p84) IPI00167260 Q8IZQ8 MYOCD Myocardin 2 IPI00027157 P49454 CENPF Mitosin (Centromere protein F) (Kinetochore protein CENP-F) (AH antigen) 2

RNA processing and ribonucleoprotein Nop10 (H/ACA ribonucleoprotein complex subunit 3) (Nucleolar A member 3) IPI00032853 Q9NPE3 NOLA3 2 (snoRNP protein NOP10) IPI00549342 Q5JRR2 RBM10 RNA binding motif protein 10 4 IPI00604620 P19338 NCL Nucleolin (Protein C23) 3 IPI00411937 O00567 NOL5A Nop56 (Nucleolar protein Nop56) (Nucleolar protein 5A) 2 SAP155 (Splicing factor 3B subunit 1) (Spliceosome-associated protein 155) (SF3b155) (Pre-mRNA- IPI00026089 O75533 SF3B1 3 splicing factor SF3b 155 kDa subunit) SAP 145 (Splicing factor 3B subunit 2) (Spliceosome-associated protein 145) (SF3b150) (Pre-mRNA- IPI00221106 Q13435 SF3B2 2 splicing factor SF3b 145 kDa subunit) PSF (Splicing factor, proline-and glutamine-rich) (Polypyrimidine tract- binding protein-associated-splicing IPI00010740 P23246 SFPQ factor) (PTB-associated-splicing factor) (DNA-binding p52/p100 complex, 100 kDa subunit) (100 kDa DNA- 3 pairing protein) (hPOMp100) NONO protein (Non-POU domain-containing octamer-binding protein) (NonO protein) (54 kDa nuclear IPI00304596 Q15233 NONO RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding 2 p52/p100 complex, 52 kDa subunit) DDX3 (ATP-dependent RNA helicase DDX3X) (DEAD box protein 3, X- chromosomal) (Helicase-like IPI00215637 O00571 DDX3X 3 protein 2) (HLP2) (DEAD box, X isoform) DDX15 (Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15) (DEAH box protein 15) IPI00396435 O43143 DHX15 4 (ATP-dependent RNA helicase #46) SRRM2 (splicing coactivator subunit SRm300) (Serine/arginine repetitive matrix protein 2) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (Ser/Arg- related IPI00782992 Q9UQ35 SRRM2 3 nuclear matrix protein) (SR-related nuclear matrix protein of 300 kDa) (300 kDa nuclear matrix antigen) IPI00302850 P62314 SNRPD1 SMD1 (Sm-D1) (Small nuclear ribonucleoprotein Sm D1) (snRNP core protein D1) (Sm-D 2 IPI00017963 P62316 SNRPD2 SMD2 (Small nuclear ribonucleoprotein Sm D2) (snRNP core protein D2) (Sm-D2) 2 hnRNP A1 (hnRNP core protein A1) (Heterogeneous nuclear ribonucleoprotein A1) (Helix- IPI00465365 P09651 HNRPA1 4 destabilizing protein) (Single-strand RNA-binding protein) IPI00386854 Q9BWA9 HNRPA2B1 hnRNP A2 (HNRPA2B1 protein) (heterogeneous nuclear ribonucleoprotein A2/B1) 2 IPI00028888 Q14103 HNRPD hnRNP D0 (Heterogeneous nuclear ribonucleoprotein D0) (AU-rich element RNA-binding protein 1) 2 IPI00013881 P31943 HNRPH1 hnRNP H (Heterogeneous nuclear ribonucleoprotein H1) 2 hnRNP K (Heterogeneous nuclear ribonucleoprotein K) (Transformation up-regulated nuclear IPI00216049 P61978 HNRPK 4 protein) (TUNP) IPI00171903 P52272 HNRPM hnRNP M (Heterogeneous nuclear ribonucleoprotein M) 2 hnRNP U (Heterogeneous nuclear ribonucleoprotein U) (Scaffold attachment factor A) (SAF-A) IPI00025054 Q00839 HNRPU 3 (p120) (pp120) IPI00017617 P17844 DDX5 DDX5 (Probable ATP-dependent RNA helicase DDX5) (DEAD box protein 5) (RNA helicase p68) 2

Protein biosynthesis IPI00012079 P23588 EIF4B eIF-4B ( initiation factor 4B) 4 IPI00014424 Q05639 EEF1A2 eEF1A-2 ( 1-alpha 2) (EF-1-alpha-2) (Elongation factor 1 A-2) (Statin S1) 2 IPI00008524 P11940 PABPC1 PABP1 (Polyadenylate-binding protein 1) (PABP) (Poly(A)-binding protein 1) (PABP 1) 2 IGF-II mRNA-binding protein 1 (insulin-like growth factor 2 mRNA binding protein 1) (MRNA-binding protein IPI00008557 Q9NZI8 IGF2BP1 2 CRDBP) IPI00419880 P61247 RPS3A S3a (40S ribosomal protein S3a) 2 IPI00011253 P23396 RPS3 Ribosomal protein S3 () 2 IPI00221093 P08708 RPS17 Ribosomal protein S17 (40S ribosomal protein S17) 2 IPI00215780 P39019 RPS19 Ribosomal protein S19 (40S ribosomal protein S19) 2 IPI00299573 P62424 RPL7A Ribosomal protein L7a (60S ribosomal protein L7a) 2 IPI00030179 P18124 RPL7 Ribosomal protein L7 () 2 IPI00024933 P30050 RPL12 Ribosomal protein L12 (60S ribosomal protein L12) 2 IPI00215719 Q07020 RPL18 Ribosomal protein L18 (60S ribosomal protein L18) 2 IPI00247583 P46778 RPL21 Ribosomal protein L21 (60S ribosomal protein L21) 2 Ribosomal protein L22 (60S ribosomal protein L22) (Epstein-Barr virus small RNA-associated IPI00219153 P35268 RPL22 3 protein) (EBER-associated protein) (EAP) (Heparin-binding protein HBp15) IPI00026302 P62899 RPL31 Ribosomal protein L31 (60S ribosomal protein L31) 2 IPI00008530 P05388 RPLP0 Ribosomal protein P0 (60S acidic ribosomal protein P0) 2 IPI00008527 P05386 RPLP1 Ribosomal protein P1 (60S acidic ribosomal protein P1) 2 IPI00008529 P05387 RPLP2 Ribosomal protein P2 (60S acidic ribosomal protein P2) 3 Ribosomal protein S4 X linked (40S ribosomal protein S4, X isoform) (Single copy abundant mRNA protein) IPI00217030 P62701 RPS4X 2 (SCR10) IPI00003918 P36578 RPL4 Ribosomal protein L4 () 2 IPI00219150 P62913 RPL11 Ribosomal protein L11 (60S ribosomal protein L11) 3 IPI00025329 P84098 RPL19 Ribosomal protein L19 (60S ribosomal protein L19) 2 IPI00219156 P62888 RPL30 Ribosomal protein L30 (60S ribosomal protein L30) 2 IPI00027270 P61254 RPL26 Ribosomal protein L26 (60S ribosomal protein L26) 2 IPI00029731 P18077 RPL35a Ribosomal protein L35a (60S ribosomal protein L35a) 2 IPI00412607 P42766 RPL35 Ribosomal protein L35 (60S ribosomal protein L35) 2 IPI00216237 Q9Y3U8 RPL36 Ribosomal protein L36 (60S ribosomal protein L36 2 IPI00025447 Q504Z0 EEF1A1 eEF1A1 (Elongation factor 1-alpha 1) (Eukaryotic translation elongation factor 1 alpha 1) 3 IPI00382804 Q14222 EEF1A eEF1A protein 2

Cellular organization Cytoskeleton constituent proteins IPI00021439 P60709 ACTB Actin β (Actin beta) (Actin, cytoplasmic 1) 5 Tubulin α-1 (Tubulin alpha-1 chain) (Alpha-tubulin 1) (Testis-specific alpha- tubulin) (Tubulin H2- IPI00007750 P68366 TUBA1 3 alpha) IPI00179709 Q13748 TUBA2 Tubulin α-2 (Tubulin alpha-2 chain) (Alpha-tubulin 2) 2 IPI00218343 Q9BQE3 TUBA6 Tubulin α-6 (Tubulin alpha-6 chain) (Alpha-tubulin 6) 3 IPI00013475 Q13885 TUBB2 Tubulin β-2A (Tubulin beta-2A chain) 2 IPI00007752 P68371 TUBB2C Tubulin β-2 (Tubulin beta-2C chain) (Tubulin beta-2 chain) 5 IPI00013683 Q13509 TUBB3 Tubulin β-3 (Tubulin beta-3 chain) (Tubulin beta-4) 2 IPI00418471 P08670 VIM Vimentin 2 IPI00023006 P68032 ACTC α-cardiac actin (Actin, alpha cardiac muscle 1) (Alpha-cardiac actin) 3

Cytoskeleton accessory proteins IPI00012011 P23528 CFL1 Cofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18) 2 Filamin A (Alpha-filamin) (Filamin-1) (Endothelial actin-binding protein) (Actin-binding protein 280) IPI00333541 P21333 FLNA 4 (ABP-280) (Nonmuscle filamin) IPI00026314 P06396 GSN Gelsolin (Actin-depolymerizing factor) (ADF) (Brevin) (AGEL) 2 IPI00005087 Q9NYL9 TMOD3 Tropomodulin-3 (Ubiquitous tropomodulin) (U-Tmod) 4 IPI00413728 Q13813 SPTAN1 α-fodrin (Spectrin, non-erythroid alpha chain) (Alpha-II spectrin) (Fodrin alpha chain) 2 Thymopoietin (Thymopoietin a) (Lamina-associated polypeptide 2 isoform alpha) (Thymopoietin isoform IPI00216230 P42166 TMPO 2 alpha) (TP alpha) (Thymopoietin-related peptide isoform alpha) (TPRP isoform alpha) IPI00032230 Q9Y2J2 EPB41L3 DAL1 (band 4.1-like protein 3 (4.1b)) (differentially expressed in adenocarcinoma of the lung protein 1) (dal- 2 IPI00020153 Q9UPA5 BSN ZNF231 (Protein bassoon) (Zinc finger protein 231) (Neuronal double zinc finger protein) 2

Motor proteins Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy chain IIa) (NMMHC II-a) IPI00019502 P35579 MYH9 2 (NMMHC-IIA) (Cellular myosin heavy chain, type A) (Nonmuscle myosin heavy chain-A) (NMMHC-A) IPI00010418 O00159 MYO1C Myosin Ic (Myosin I beta) (MMI-beta) (MMIb) 2 Myosin light chain (MYL6 protein) (Myosin light polypeptide 6) (Smooth muscle and nonmuscle IPI00335168 P60660 MYL6 2 myosin light chain alkali 6) (Myosin light chain alkali 3) (Myosin light chain 3) (MLC-3) (LC17)

Metabolic PK3 ( 3) (Pyruvate kinase M 2) (Pyruvate kinase isozymes M1/M2) (Pyruvate kinase IPI00383237 P14618 PKM2 2 muscle isozyme) (Pyruvate kinase 2/3) (Cytosolic thyroid hormone-binding protein) (CTHBP) IPI00219018 P04406 GAPDH GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) 2 Cyclophilin A (Peptidyl-prolyl cis-trans A) (PPIase A) (Rotamase A) (Cyclophilin A) IPI00419585 P62937 PPIA 2 (Cyclosporin A-binding protein)

Chaperone and stress response IPI00003865 P11142 HSPA8 HSC70 (Heat shock cognate 71 kDa protein) (Heat shock 70 kDa protein 8) 3 IPI00304925 P08107 HSP70 HSP70.1 (Heat shock 70 kDa protein 1) (HSP70-1/HSP70-2) 2 HSP70-Hom (Heat shock 70 kDa protein 1L) (Heat shock 70 kDa protein 1-like) (Heat shock 70 kDa protein IPI00301277 P34931 HSPA1L 2 1-Hom) IPI00414676 P08238 HSP90B HSP90 (Heat shock protein HSP 90-beta) (HSP 84) 2 IPI00339269 P17066 HSPA6 HSPA6 (Heat shock 70 kDa protein 6) 3

Miscellaneous Apoptosis IPI00006079 Q9NYF8 BCLAF1 BTF (Bcl-2-associated transcription factor 1) (Btf) 5 BIP (78 kDa glucose-regulated protein precursor) (GRP 78) (Heat shock 70 kDa protein 5) IPI00003362 P11021 HSPA5 (Immunoglobulin heavy chain-binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+)-binding 2 protein grp78)

Proteolysis and ubiquitination IPI00179330 Q5RKT7 RPS27A Ubiquitin and ribosomal protein S27a 3 IPI00719280 Q5U5U6 UBB Ubiquitin B 2 IPI00784990 Q5UGI3 UBC Ubiquitin C 3 Calpain-1 catalytic subunit (Calpain-1 large subunit) (Calcium-activated neutral proteinase 1) (CANP 1) IPI00011285 P07384 CAPN1 2 (Calpain mu-type) (muCANP) (Micromolar-calpain) IPI00216003 Q93034 CUL5 Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor) (VACM-1) 2

Others IPI00550655 Q9Y657 SPIN Spindlin-1 (Ovarian cancer-related protein) 2 IPI00174535 Q5JUX0 SPIN3 Spindlin-3 (Spindlin-like protein 3) (SPIN-3) 2 IPI00010849 P05814 CSN2 β-casein (Casein beta) 2 IPI00001639 Q14974 KPNB1 Importin 90 (Importin beta-1 subunit) (Karyopherin beta-1 subunit) (Nuclear factor P97) 2 TER ATPase (Transitional endoplasmic reticulum ATPase) (15S Mg(2+)- ATPase p97 subunit) (Valosin- IPI00022774 P55072 VCP 2 containing protein) (VCP)

Unknown IPI00012202 Q9BQA1 WDR77 Methylosome protein 50 4 IPI00003269 Hypothetical protein LOC345651 5 IPI00419322 Q7Z4V5 HDGF2 HDGF2 (Hepatoma-derived growth factor 2) (HGDF-related pro 2) 2 IPI00301434 Q9H3K6 BOLA2 BolA-like protein 2 (BolA-like protein My016) 2 Mob4B protein (Mps one binder kinase activator-like 1B (Mob1 homolog 1B) (Mob1 alpha) (Mob1A) IPI00301518 Q9H8S9 MOBK1B (Protein Mob4B) Hypothetical protein FLJ10100 (CDNA FLJ10100 FIS, CLONE HEMBA1002469, MODERATELY SIMILAR IPI00029969 Q9NWD7 2 TO DXS8237E PROTEIN) PREDICTED: similar to FKSG30 (PREDICTED: similar to Prostate, ovary, testis expressed protein IPI00401614 2 on 2 ) IPI00413922 11 kDa protein 2 IPI00455475 PREDICTED: similar to cytoskeletal β actin 4 IPI00444605 Q6ZSQ4 Hypothetical protein FLJ45296 3 IPI00742813 Similar to PI-3-kinase-related kinase SMG-1 isoform 1 2 IPI00550724 Similar to Actin, cytoplasmic 2 4 nsun2 protein (NOL1/NOP2/Sun domain family 2 protein) (NOL1/NOP2/Sun domain family 2) (putative 5- IPI00306369 Q08J23 NSUN2 2 methycytoisine methyltransferase) IPI00185448 Hypothetical protein DKFZp566G0346 2