DOCSLIB.ORG

Safety Data Sheet

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Safety Data Sheet SAFETY DATA SHEET Revision Date 19-Feb-2021 Revision Number 2 SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1. Product identifier Product Description: Chlorodimethylsilane Cat No. : A13113 CAS-No 1066-35-9 Molecular Formula C2 H7 ClSi 1.2. Relevant identified uses of the substance or mixture and uses advised against Recommended Use Laboratory chemicals. Uses advised against No Information available 1.3. Details of the supplier of the safety data sheet Company Alfa Aesar . Avocado Research Chemicals, Ltd. Shore Road Port of Heysham Industrial Park Heysham, Lancashire LA3 2XY United Kingdom Office Tel: +44 (0) 1524 850506 Office Fax: +44 (0) 1524 850608 E-mail address [email protected] www.alfa.com Product Safety Department 1.4. Emergency telephone number Call Carechem 24 at +44 (0) 1865 407333 (English only); +44 (0) 1235 239670 (Multi-language) SECTION 2: HAZARDS IDENTIFICATION 2.1. Classification of the substance or mixture CLP Classification - Regulation (EC) No 1272/2008 Physical hazards Flammable liquids Category 1 (H224) Health hazards Skin Corrosion/Irritation Category 1 B (H314) ______________________________________________________________________________________________ ALFAAA13113 Page 1 / 11 SAFETY DATA SHEET Chlorodimethylsilane Revision Date 19-Feb-2021 ______________________________________________________________________________________________ Serious Eye Damage/Eye Irritation Category 1 (H318) Specific target organ toxicity - (single exposure) Category 3 (H335) Environmental hazards Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16 2.2. Label elements Signal Word Danger Hazard Statements H224 - Extremely flammable liquid and vapor H314 - Causes severe skin burns and eye damage H335 - May cause respiratory irritation Precautionary Statements P280 - Wear protective gloves/protective clothing/eye protection/face protection P301 + P330 + P331 - IF SWALLOWED: Rinse mouth. Do NOT induce vomiting P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor/physician P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking 2.3. Other hazards Substance is not considered persistent, bioaccumulative and toxic (PBT) / very persistent and very bioaccumulative (vPvB) SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.1. Substances Component CAS-No EC-No. Weight % CLP Classification - Regulation (EC) No 1272/2008 Silane, chlorodimethyl- 1066-35-9 EEC No. 213-912-0 <=100 Skin Corr. 1B (H314) Eye Dam. 1 (H318) STOT SE 3 (H335) Flam. Liq. 1 (H224) Full text of Hazard Statements: see section 16 ______________________________________________________________________________________________ ALFAAA13113 Page 2 / 11 SAFETY DATA SHEET Chlorodimethylsilane Revision Date 19-Feb-2021 ______________________________________________________________________________________________ SECTION 4: FIRST AID MEASURES 4.1. Description of first aid measures General Advice Show this safety data sheet to the doctor in attendance. Immediate medical attention is required. Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Immediate medical attention is required. Skin Contact Wash off immediately with plenty of water for at least 15 minutes. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Call a physician immediately. Ingestion Do NOT induce vomiting. Clean mouth with water. Never give anything by mouth to an unconscious person. Call a physician immediately. Inhalation If not breathing, give artificial respiration. Remove from exposure, lie down. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; give artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Call a physician immediately. Self-Protection of the First Aider Ensure that medical personnel are aware of the material(s) involved, take precautions to protect themselves and prevent spread of contamination. 4.2. Most important symptoms and effects, both acute and delayed Causes burns by all exposure routes. Difficulty in breathing. Inhalation of high vapor concentrations may cause symptoms like headache, dizziness, tiredness, nausea and vomiting: Product is a corrosive material. Use of gastric lavage or emesis is contraindicated. Possible perforation of stomach or esophagus should be investigated: Ingestion causes severe swelling, severe damage to the delicate tissue and danger of perforation 4.3. Indication of any immediate medical attention and special treatment needed Notes to Physician Treat symptomatically. SECTION 5: FIREFIGHTING MEASURES 5.1. Extinguishing media Suitable Extinguishing Media Dry sand. Carbon dioxide (CO 2). Powder. Do not use water or foam. CO 2, dry chemical, dry sand, alcohol-resistant foam. Water mist may be used to cool closed containers. Extinguishing media which must not be used for safety reasons No information available. 5.2. Special hazards arising from the substance or mixture Thermal decomposition can lead to release of irritating gases and vapors. The product causes burns of eyes, skin and mucous membranes. Extremely flammable. Containers may explode when heated. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Hazardous Combustion Products Carbon monoxide (CO), Carbon dioxide (CO2), Hydrogen chloride, Silicon dioxide. ______________________________________________________________________________________________ ALFAAA13113 Page 3 / 11 SAFETY DATA SHEET Chlorodimethylsilane Revision Date 19-Feb-2021 ______________________________________________________________________________________________ 5.3. Advice for firefighters As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear. Thermal decomposition can lead to release of irritating gases and vapors. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1. Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. Use personal protective equipment as required. Evacuate personnel to safe areas. Keep people away from and upwind of spill/leak. Remove all sources of ignition. Take precautionary measures against static discharges. 6.2. Environmental precautions Should not be released into the environment. See Section 12 for additional Ecological Information. 6.3. Methods and material for containment and cleaning up Soak up with inert absorbent material. Keep in suitable, closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. 6.4. Reference to other sections Refer to protective measures listed in Sections 8 and 13. SECTION 7: HANDLING AND STORAGE 7.1. Precautions for safe handling Wear personal protective equipment/face protection. Do not get in eyes, on skin, or on clothing. Use only under a chemical fume hood. Do not breathe mist/vapors/spray. Do not ingest. If swallowed then seek immediate medical assistance. Keep away from open flames, hot surfaces and sources of ignition. Use spark-proof tools and explosion-proof equipment. Use only non-sparking tools. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded. Take precautionary measures against static discharges. Hygiene Measures Handle in accordance with good industrial hygiene and safety practice. Keep away from food, drink and animal feeding stuffs. Do not eat, drink or smoke when using this product. Remove and wash contaminated clothing and gloves, including the inside, before re-use. Wash hands before breaks and after work. 7.2. Conditions for safe storage, including any incompatibilities Keep refrigerated. Corrosives area. Keep containers tightly closed in a dry, cool and well-ventilated place. Keep away from heat, sparks and flame. Technical Rules for Hazardous Substances (TRGS) 510 Storage Class (LGK) Class 3 (Germany) 7.3. Specific end use(s) Use in laboratories SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1. Control parameters Exposure limits ______________________________________________________________________________________________ ALFAAA13113 Page 4 / 11 SAFETY DATA SHEET Chlorodimethylsilane Revision Date 19-Feb-2021 ______________________________________________________________________________________________ This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies Biological limit values This product, as supplied, does not contain any hazardous materials with biological limits established by the region specific regulatory bodies Monitoring methods BS EN 14042:2003 Title Identifier: Workplace atmospheres. Guide for the application and use of procedures for the assessment of exposure to chemical and biological agents. MDHS70 General methods for sampling airborne gases and vapours MDHS 88 Volatile organic compounds in air. Laboratory method using diffusive samplers, solvent desorption and gas chromatography MDHS 96 Volatile organic compounds in air - Laboratory method using pumped solid sorbent tubes,
Load more

Recommended publications
  • EPA Handbook: Optical and Remote Sensing for Measurement and Monitoring of Emissions Flux of Gases and Particulate Matter
    EPA Handbook: Optical and Remote Sensing for Measurement and Monitoring of Emissions Flux of Gases and Particulate Matter EPA 454/B-18-008 August 2018 EPA Handbook: Optical and Remote Sensing for Measurement and Monitoring of Emissions Flux of Gases and Particulate Matter U.S. Environmental Protection Agency Office of Air Quality Planning and Standards Air Quality Assessment Division Research Triangle Park, NC EPA Handbook: Optical and Remote Sensing for Measurement and Monitoring of Emissions Flux of Gases and Particulate Matter 9/1/2018 Informational Document This informational document describes the emerging technologies that can measure and/or identify pollutants using state of the science techniques Forward Optical Remote Sensing (ORS) technologies have been available since the late 1980s. In the early days of this technology, there were many who saw the potential of these new instruments for environmental measurements and how this technology could be integrated into emissions and ambient air monitoring for the measurement of flux. However, the monitoring community did not embrace ORS as quickly as anticipated. Several factors contributing to delayed ORS use were: • Cost: The cost of these instruments made it prohibitive to purchase, operate and maintain. • Utility: Since these instruments were perceived as “black boxes.” Many instrument specialists were wary of how they worked and how the instruments generated the values. • Ease of use: Many of the early instruments required a well-trained spectroscopist who would have to spend a large amount of time to setup, operate, collect, validate and verify the data. • Data Utilization: Results from path integrated units were different from point source data which presented challenges for data use and interpretation.
    [Show full text]
  • The Synthesis and Characterization of Binuclear Zirconocene Complexes and Their Study As Initiators in the Polymerization of M
    END-GROUP FUNCTIONALIZATION OF ANIONICALLY SYNTHESIZED POLYMERS VIA HYDROSILATION REACTIONS A Dissertation Presented to The Graduate Faculty of The University of Akron In Partial Fulfillment of the Requirements for the Degree Doctor of Philosophy Hoon Kim May, 2006 END-GROUP FUNCTIONALIZATION OF ANIONICALLY SYNTHESIZED POLYMERS VIA HYDROSILATION REACTIONS Hoon Kim Dissertation Approved: Accepted: Advisor Department Chair Dr. Roderic P. Quirk Dr. Mark D. Foster Committee Member Dean of the College Dr. Joseph P. Kennedy Dr. Frank N. Kelley Committee Member Dean of the Graduate School Dr. William Brittain Dr. George R. Newkome Committee Member Date Dr. Coleen Pugh Committee Member Dr. Chrys Wesdemiotis ii ABSTRACT One of the unique features of living, alkyllithium-initiated, anionic polymerization is the ability to produce a stable carbanionic chain end after complete monomer consumption, which can be followed by reaction with electrophiles to form various end- functionalized polymers. Although a variety of functional polymers have been synthesized in the last few decades, each specific functionalization has had to be designed and optimized individually. Consequently, the development of general functionalization methodologies has drawn recent interest. However, even these general functionalization methods require the use of protecting groups, and the complexity in synthetic routes and the thermal/moisture instability of many protected functional agents have restricted their practical application. This thesis describes a new, general functionalization methodology, combining well-defined, living anionic polymerization with efficient and highly selective, platinum-catalyzed hydrosilation reactions with functionalized alkenes. Well-defined, Si-H functionalized polymers (P-SiH) have been synthesized by sec- butyllithium-initiated, living anionic polymerization in benzene followed by termination with dimethylchlorosilane.
    [Show full text]
  • A Review of Organosilanes in Organic Chemistry
    A Review of Organosilanes in Organic Chemistry • Silyl Protecting and Derivatisation Reagents • Organosilanes as Reducing Agents • Silanes in Cross-coupling Chemistry • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations INTRODUCTION Organosilanes have varied uses in organic chemistry from the most frequently employed protecting groups to intermediates in organic synthesis. The Acros Organics portfolio of organosilanes is continuously expanding to meet your chemistry needs. In this brochure you will find an overview of four of the most important applications of organosilanes: • Silyl Protecting and Derivatisation Reagents 1, 2 • Organosilanes as Reducing Agents 3 • Silanes in Cross-coupling Chemistry 4 • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations4 Silyl Protecting and Derivatisation Reagents Silicon protecting groups are probably the most frequently employed of all protecting groups, and modern natural product synthesis is inconceivable without them.5 Silylating agents are mostly used to protect alcohols and phenols, but have also found application in the protection of amines, carboxylic acids, amides, thiols and alkynes. By varying the substituents attached to silicon, the steric and electronic characteristics of the protecting group can be finely tuned, allowing a wide variety of both reaction and deprotection conditions. The leaving group also plays an important role in the reactivity and use of silylating reagents. Whilst chlorotrimethylsilane [product code: 42643] liberates hydrogen chloride on reaction,
    [Show full text]
  • Hazardous Substances (Chemicals) Transfer Notice 2006
    16551655 OF THURSDAY, 22 JUNE 2006 WELLINGTON: WEDNESDAY, 28 JUNE 2006 — ISSUE NO. 72 ENVIRONMENTAL RISK MANAGEMENT AUTHORITY HAZARDOUS SUBSTANCES (CHEMICALS) TRANSFER NOTICE 2006 PURSUANT TO THE HAZARDOUS SUBSTANCES AND NEW ORGANISMS ACT 1996 1656 NEW ZEALAND GAZETTE, No. 72 28 JUNE 2006 Hazardous Substances and New Organisms Act 1996 Hazardous Substances (Chemicals) Transfer Notice 2006 Pursuant to section 160A of the Hazardous Substances and New Organisms Act 1996 (in this notice referred to as the Act), the Environmental Risk Management Authority gives the following notice. Contents 1 Title 2 Commencement 3 Interpretation 4 Deemed assessment and approval 5 Deemed hazard classification 6 Application of controls and changes to controls 7 Other obligations and restrictions 8 Exposure limits Schedule 1 List of substances to be transferred Schedule 2 Changes to controls Schedule 3 New controls Schedule 4 Transitional controls ______________________________ 1 Title This notice is the Hazardous Substances (Chemicals) Transfer Notice 2006. 2 Commencement This notice comes into force on 1 July 2006. 3 Interpretation In this notice, unless the context otherwise requires,— (a) words and phrases have the meanings given to them in the Act and in regulations made under the Act; and (b) the following words and phrases have the following meanings: 28 JUNE 2006 NEW ZEALAND GAZETTE, No. 72 1657 manufacture has the meaning given to it in the Act, and for the avoidance of doubt includes formulation of other hazardous substances pesticide includes but
    [Show full text]
  • Dräger Gas List 2015 List of Detectable Gases and Vapours Dräger Gas List 2015 List of Detectable Gases and Vapours
    D-34313-2009 Dräger Gas List 2015 List of detectable gases and vapours Dräger Gas List 2015 List of detectable gases and vapours Gas list to find a suitable fixed installed Dräger gas detection instrument for the detection of a specified substance Edition July 2015 Subject to alteration Dräger Safety AG & Co. KGaA Lübeck, 2015 04 | DRÄGER GAS LIST 2015 | SEARCH INDEXES Search Indexes This list of gases consists of three search indexes and the main part. The search indexes are suitable to find the substance in question by having only its CAS-number, its name (including short name or technical abbreviation), or its sum formula. Using the search indexes you will obtain the substance’s Search Index for Sum formula For every chemical formula - normally associated number to look for in the list of gases. given as a semi-structure formula - a If the substance is not listed, this does not necessarily sum formula exists. A sum formula is mean that this substance is not detectable. formed according to the Hill-system: Within each sum formula the element symbol C (for Carbon) is on the first Search Index for CAS-Number When searching 1.2-Dichloroethane place, the element symbol H (for The CAS-number is a worldwide used look for Dichloroethane, find tert- Hydrogen) on the second, followed by code to identify a chemical substance Butanol under Butanol and Methyl- all other element symbols in alphabetical non-ambiguously. This number is issued tertbutylether under Methylbutylether. order. For every element symbol the by the Chemical Abstracts Service order is given with increasing number of and is the easiest way to characterise This search index also lists short names atoms of the corresponding molecule.
    [Show full text]
  • SILICONES USED for FOOD CONTACT APPLICATIONS Version 1 Œ 10.06.2004
    PUBLIC HEALTH COMMITTEE COMMITTEE OF EXPERTS ON MATERIALS COMING INTO CONTACT WITH FOOD POLICY STATEMENT CONCERNING SILICONES USED FOR FOOD CONTACT APPLICATIONS Version 1 œ 10.06.2004 NOTE TO THE READER The following documents are part of the Policy statement concerning silicones used for food contact applications: Resolution ResAP (2004) 5 on silicones to be used for food contact applications Technical document No. 1 œ List of substances to be used in the manufacture of silicones used for food contact applications The documents are available on the Internet website of the Partial Agreement Division in the Social and Public Health Field: www.coe.int/soc-sp 2 TABLE OF CONTENTS Page Resolution ResAP (2004) 5 on silicones to be used for food contact applications ……………………………………………………………………….……. 4 Technical document No. 1 œ List of substances to be used in the manufacture of silicones used for food contact applications ……………………… 8 3 RESOLUTION RESAP (2004) 5 ON SILICONES USED FOR FOOD CONTACT APPLICATIONS 4 RESOLUTION RESAP (2004) 5 ON SILICONES USED FOR FOOD CONTACT APPLICATIONS (adopted by the Committee of Ministers on 1st December 2004 at the 907 th meeting of the Ministers‘ Deputies) (superseding Resolution AP AP (99) 3) The Committee of Ministers, in its composition restricted to the Representatives of Austria, Belgium, Cyprus, Denmark, Finland, France, Germany, Ireland, Italy, Luxembourg, The Netherlands, Norway, Portugal, Slovenia, Spain, Sweden, Switzerland and the United Kingdom, member states of the Partial Agreement in the Social and Public Health Field, Recalling Resolution (59) 23 of 16 November 1959, concerning the extension of the activities of the Council of Europe in the social and cultural fields; Having regard to Resolution (96) 35 of 2 October 1996, whereby it revised the structures of the Partial Agreement and resolved to continue, on the basis of revised rules replacing those set out in Resolution (59) 23, the activities hitherto carried out and developed by virtue of that resolution; these being aimed in particular at: a.
    [Show full text]
  • Cocam 4, 16-18 April 2013 US/ICCA 1 SIDS INITIAL ASSESSMENT PROFILE Category Name Monomeric Chlorosilanes CAS No(S). 1066-35-9 7
    CoCAM 4, 16-18 April 2013 US/ICCA SIDS INITIAL ASSESSMENT PROFILE Category Name Monomeric Chlorosilanes 1066-35-9 75-54-7 CAS No (s). 10025-78-2 10026-04-7 Chlorodimethylsilane (ClMe2SiH) Dichloromethylsilane (Cl2MeSiH) Chemical Name(s) Trichlorosilane (Cl3SiH) Tetrachlorosilane (Cl4Si) ClMe2SiH Structural Formula(s) Cl2MeSiH Cl3SiH This document may only be reproduced integrally. The conclusions and recommendations (and their rationale) in this document are intended to be mutually supportive, and should be understood and interpreted together. 1 CoCAM 4, 16-18 April 2013 US/ICCA Cl4Si SUMMARY CONCLUSIONS OF THE SIAR Analogue/Category Rationale These chemicals can be represented by a similar general molecular formula: (Cl)xSi(H)y(Me)z Where Cl = chlorine, x = 1, 2, 3, or 4; Si = silicon [=1]; H = hydrogen, y = 0 or 1; if y = 0, then x = 4 Me = CH3, z = 0, 1, or 2 Chlorosilanes react rapidly when exposed to moisture or polar reagents (those that contain a dissociable H+), producing hydrogen chloride (HCl; CAS No. 7647-01-0) and the corresponding silanols (in general, siloxane oligomers and polymers). The half lives of the monomeric chlorosilanes are expected to be < 1 minute based on data from the structurally similar chlorosilanes dichloro(dimethyl)silane (Cl2DMS) and trichloro(methyl)silane (Cl3MS). Data are not available on the hydrolysis of these compounds. However, the following is expected: ClMe2SiH is expected to hydrolyze to form one mole each of HCl and dimethylsilanol (note that dimethylsilanol can hydrolyze to form dimethylsilanediol (DMSD) ultimately through hydrolysis of the SiH bond, which is pH dependent and occurs most rapidly under alkaline conditions).
    [Show full text]
  • Synthesis of Hydrogenated Thiol-Silanes for Selective Reactions Macartney Welborn Southern Methodist University, [email protected]
    Southern Methodist University SMU Scholar Collection of Engaged Learning Engaged Learning Fall 11-23-2014 Synthesis of Hydrogenated Thiol-Silanes for Selective Reactions Macartney Welborn Southern Methodist University, [email protected] Follow this and additional works at: https://scholar.smu.edu/upjournal_research Part of the Chemistry Commons Recommended Citation Welborn, Macartney, "Synthesis of Hydrogenated Thiol-Silanes for Selective Reactions" (2014). Collection of Engaged Learning. 64. https://scholar.smu.edu/upjournal_research/64 This document is brought to you for free and open access by the Engaged Learning at SMU Scholar. It has been accepted for inclusion in Collection of Engaged Learning by an authorized administrator of SMU Scholar. For more information, please visit http://digitalrepository.smu.edu. Macartney Welborn ! ! ! ! ! ! ! ! Synthesis of Hydrogenated Thiol-Silanes for Selective Reactions ! ! Engaged Learning Final Report! ! Macartney Welborn! Mentor: Dr. David Son Ph.D. ! ! ! "1 Macartney Welborn Synthesis of Hydrogenated Thiol-Silanes for Selective Reactions Engaged Learning Final Report ! Abstract The intention of this experiment is to show the creation of multifunctional thiols from the reaction between various hydrochlorosilanes and mercaptoethanol in an attempt to utilize their distinct properties for practical applications. Multifunctional thiols have many useful applications including use in high-refractive-index lenses,1 heavy metal chelation,2 and degradable plastics.3 Previous work,5 in our lab has explored a class of reactions key to the synthesis of these compounds: the reaction between methylated chlorosilanes with mercaptoalcohols. We extended this reaction to include hydrogenated chlorosilanes. This allows us to produce multifunctional thiols with an additional functionalizable position at the hydrogen, allowing for greater flexibility in regards to practical applications.
    [Show full text]
  • A Review of Organosilanes in Organic Chemistry
    A Review of Organosilanes in Organic Chemistry • Silyl Protecting and Derivatisation Reagents • Organosilanes as Reducing Agents • Silanes in Cross-coupling Chemistry • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations INTRODUCTION Organosilanes have varied uses in organic chemistry from the most frequently employed protecting groups to intermediates in organic synthesis. The Acros Organics portfolio of organosilanes is continuously expanding to meet your chemistry needs. In this brochure you will find an overview of four of the most important applications of organosilanes: • Silyl Protecting and Derivatisation Reagents 1, 2 • Organosilanes as Reducing Agents 3 • Silanes in Cross-coupling Chemistry 4 • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations4 Silyl Protecting and Derivatisation Reagents Silicon protecting groups are probably the most frequently employed of all protecting groups, and modern natural product synthesis is inconceivable without them.5 Silylating agents are mostly used to protect alcohols and phenols, but have also found application in the protection of amines, carboxylic acids, amides, thiols and alkynes. By varying the substituents attached to silicon, the steric and electronic characteristics of the protecting group can be finely tuned, allowing a wide variety of both reaction and deprotection conditions. The leaving group also plays an important role in the reactivity and use of silylating reagents. Whilst chlorotrimethylsilane [product code: 42643] liberates hydrogen chloride on reaction,
    [Show full text]
  • Global Safe Handling of Chlorosilanes
    GLOBAL SAFE HANDLING OF CHLOROSILANES Developed by the Operating Safety Committees of the Silicones Environmental, Health and Safety Center, CES-Silicones Europe, in partnership with the Silicones Industry Association of Japan October 2017 TABLE OF CONTENTS CHAPTER 1 - INTRODUCTION 3 CHAPTER 2 - CHLOROSILANE NOMENCLATURE 5 CHAPTER 3 - HEALTH FACTORS 6 3.1 GENERAL 6 3.2 ACUTE TOXICITY 6 3.3 CHRONIC TOXICITY 8 CHAPTER 4 - PERSONAL PROTECTIVE EQUIPMENT 9 4.1 GENERAL 9 4.2 PROTECTIVE EQUIPMENT 9 CHAPTER 5 - TRAINING AND JOB SAFETY 12 CHAPTER 6 - FIRE HAZARDS AND FIRE PROTECTION 13 6.1 FIRE HAZARDS 13 6.2 FIRE PREVENTION 13 6.3 EXTINGUISHING AGENTS 14 6.4 MANUAL FIRE FIGHTING 15 6.5 FIXED FIRE PROTECTION 16 6.6 PLUME AND VAPOR CLOUD MITIGATION 17 CHAPTER 7 - SPILL CONTAINMENT AND ENVIRONMENTAL 19 IMPACT CHAPTER 8 - INSTABILITY AND REACTIVITY HAZARDS 20 8.1 INSTABILITY HAZARDS 20 8.2 REACTIVITY HAZARDS 20 CHAPTER 9 - MINIMUM ENGINEERING CONTROL OF HAZARDS 22 9.1 BUILDING DESIGN 22 9.2 EQUIPMENT DESIGN 22 9.3 VENTILATION 25 9.4 ELECTRICAL EQUIPMENT 25 9.5 STATIC ELECTRICITY 25 CHAPTER 10 - SHIPPING, LABELLING AND MARKING 27 CHAPTER 11 - HANDLING OF BULK CONTAINERS, DRUMS, PRESSURE DRUMS AND PRESSURE CYLINDERS 28 CHAPTER 12 - WASTE DISPOSAL 33 CHAPTER 13 - EQUIPMENT CLEANING AND REPAIRS 34 Update on October 2, 2017 2 GLOBAL SAFE HANDLING OF CHLOROSILANES CHAPTER 1. INTRODUCTION The Silicones Environmental, Health and Safety Center (SEHSC) and CES-Silicones Europe are not-for-profit trade associations comprised of North American and European silicone chemical producers and importers.
    [Show full text]
  • Safety Data Sheet
    SAFETY DATA SHEET Revision Date 14-Feb-2020 Revision Number 2 1. Identification Product Name Chlorodimethylsilane Cat No. : A13113 CAS-No 1066-35-9 Synonyms No information available Recommended Use Laboratory chemicals. Uses advised against Food, drug, pesticide or biocidal product use. Details of the supplier of the safety data sheet Company Alfa Aesar Thermo Fisher Scientific Chemicals, Inc. 30 Bond Street Ward Hill, MA 01835-8099 Tel: 800-343-0660 Fax: 800-322-4757 Email: [email protected] www.alfa.com Emergency Telephone Number During normal business hours (Monday-Friday, 8am-7pm EST), call (800) 343-0660. After normal business hours, call Carechem 24 at (866) 928-0789. 2. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Flammable liquids Category 1 Skin Corrosion/Irritation Category 1 B Serious Eye Damage/Eye Irritation Category 1 Specific target organ toxicity (single exposure) Category 3 Target Organs - Respiratory system. Label Elements Signal Word Danger Hazard Statements Extremely flammable liquid and vapor Causes severe skin burns and eye damage May cause respiratory irritation ______________________________________________________________________________________________ Page 1 / 8 Chlorodimethylsilane Revision Date 14-Feb-2020 ______________________________________________________________________________________________ Precautionary Statements Prevention Do not breathe dust/fume/gas/mist/vapors/spray Wash face, hands and any exposed
    [Show full text]
  • A Review of Organosilanes in Organic Chemistry
    A Review of Organosilanes in Organic Chemistry • Silyl Protecting and Derivatisation Reagents • Organosilanes as Reducing Agents • Silanes in Cross-coupling Chemistry • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations INTRODUCTION Organosilanes have varied uses in organic chemistry from the most frequently employed protecting groups to intermediates in organic synthesis. The Acros Organics portfolio of organosilanes is continuously expanding to meet your chemistry needs. In this brochure you will find an overview of four of the most important applications of organosilanes: • Silyl Protecting and Derivatisation Reagents 1, 2 • Organosilanes as Reducing Agents 3 • Silanes in Cross-coupling Chemistry 4 • Allylsilanes Used to Stabilize α-Carbanions and β-Carbocations4 Silyl Protecting and Derivatisation Reagents Silicon protecting groups are probably the most frequently employed of all protecting groups, and modern natural product synthesis is inconceivable without them.5 Silylating agents are mostly used to protect alcohols and phenols, but have also found application in the protection of amines, carboxylic acids, amides, thiols and alkynes. By varying the substituents attached to silicon, the steric and electronic characteristics of the protecting group can be finely tuned, allowing a wide variety of both reaction and deprotection conditions. The leaving group also plays an important role in the reactivity and use of silylating reagents. Whilst chlorotrimethylsilane [product code: 42643] liberates hydrogen chloride on reaction,
    [Show full text]