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[Keith W. Ward and Brian R. Smith, A Comprehensive Quantitative and Qualitative Evaluation of Extrapolation of Intravenous Pharmacokinetic Parameters from Rat, Dog, and Monkey to Humans. I. Clearance. Drug Metab Dispos 2004 32: 603-611]

APPENDIX

Compounds for which intravenous pharmacokinetic data in the rat, dog, monkey, and human were compiled for this extrapolation exercise (full list of References below).

Acivicin Dolasetron Moxestrol 1-Aminocyclopropane L-DOPA Moxifloxacin carboxylic acid Actisomide Doxorubicin Naltrexone Acyclovir Erythromycin Naproxen Alfentanil Ethosuxamide Napsagatran Amifloxacin Nicardipine Amphotericin B FCE 22101 Nicotine Antipyrine Fentanyl Nimodipine 3'-Azido-3'deoxythymidine Fleroxacin N-(phosphonacetyl)-L- aspartate Betamipron Flunisolide Pelrinone Fluvastatin Phencyclidine BRL 42715 Furosemide Caffeine Gabapentin Pirmenol Captopril GV150526 Prednisone HI-6 Propranolol Cefclidine Ifetroban Quinidine Iloprost Recainam Indomethacin Remikiren Inogatran Ro 25-6833 Iododoxorubicin SCH 34343 Ironotecan Sudoxicam Isosorbide dinitrate Susalimod Isosorbide mononitrate Tebufelone Ketorolac Tiazofurin Lamifiban Tiludronate Ciprofloxacin Lamivudine Trimethadione Citalopram Lidocaine Troglitazone Clonazepam Meperidine Trovafloxacin Cocaine Valproic acid Coumarin Methotrexate Vinblastine Cyclophosphamide Metoprolol Vincristine Diclofenac MK-571 Warfarin Didanosine Morphine Disopyramide Moxalactam

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