INSIDE: Details on over 200 live continuing education events in 2016. Find out where to visit, what you’ll learn and who will be lecturing at CE courses big and small, from coast to coast and around the world, all year long.

A supplement to

FINAL COVER.indd 1 12/3/15 12:22 PM For allergic conjunctivitis1 THE POWER TO CALM THE ITCH

BEPREVE®—FIRST-LINE, YEAR-ROUND, WITH BROAD-SPECTRUM ALLERGEN COVERAGE

Scan this QR code or visit beprevecoupon.com to • Order samples • Learn about the automatic co-pay program • Help your patients find participating pharmacies

INDICATION AND USAGE ® BEPREVE (bepotastine besilate ophthalmic solution) 1.5% is a histamine H1 receptor antagonist indicated for the treatment of itching associated with signs and symptoms of allergic conjunctivitis. IMPORTANT RISK INFORMATION BEPREVE® is contraindicated in patients with a history of hypersensitivity reactions to bepotastine or any of the other ingredients. BEPREVE® is for topical ophthalmic use only. To minimize risk of contamination, do not touch the dropper tip to any surface. Keep the bottle closed when not in use. BEPREVE® should not be used to treat contact lens–related irritation. Remove contact lenses prior to instillation of BEPREVE®. Made by the trusted eye-care The most common adverse reaction occurring in approximately 25% of specialists at patients was a mild taste following instillation. Other adverse reactions occurring in 2%‐5% of patients were eye irritation, headache, and nasopharyngitis. Please see the accompanying prescribing information for BEPREVE® on the following page. Reference: 1. BEPREVE [package insert]. Tampa, FL: Bausch + Lomb, Inc; 2012.

For product-related questions and concerns, call 1-800-323-0000 or visit www.bepreve.com. ®/TM are trademarks of Bausch & Lomb Incorporated or its affiliates. ©2014 Bausch & Lomb Incorporated. US/BEP/12/0026(1) 1/14

RO0214_BL Bepreve.indd 1 1/16/14 9:52 AM BEPREVE® (bepotastine besilate ophthalmic solution) 1.5% women. Because animal reproduction studies are cytochrome P450 substrate via inhibition of HIGHLIGHTS OF PRESCRIBING INFORMATION ------WARNINGS AND PRECAUTIONS------not always predictive of human response, CYP3A4, CYP2C9, and CYP2C19. The effect of ® These highlights do not include all the information t

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Following a single 3 mg/kg oral dose of radiolabeled Excretion: The main route of elimination of solution) 1.5% BEPREVE. (5.2) bepotastine besilate to nursing rats 11 days after bepotastine besilate is urinary excretion (with Initial U.S. Approval: 2009 ------ADVERSE REACTIONS------delivery, the maximum concentration of radioactivity approximately 75-90% excreted unchanged in urine). ------RECENT MAJOR CHANGES------in milk was 0.40 mcg-eq/mL 1 hour after The most common adverse reaction occurring in 13 NONCLINICAL TOXICOLOGY Contraindications (4) 06/2012 administration; at 48 hours after administration the approximately 25% of patients was a mild taste 13.1 Carcinogenesis, Mutagenesis and concentration was below detection limits. The milk ------INDICATIONS AND USAGE------following instillation. Other adverse reactions Impairment of Fertility concentration was higher than the maternal blood BEPREVE® is a histamine H1 receptor antagonist which occurred in 2-5% of subjects were eye Long-term dietary studies in mice and rats were plasma concentration at each time of measurement. indicated for the treatment of itching associated irritation, headache, and nasopharyngitis. (6) conducted to evaluate the carcinogenic potential with allergic conjunctivitis. (1) It is not known if bepotastine besilate is excreted of bepotastine besilate. Bepotastine besilate did To report SUSPECTED ADVERSE REACTIONS, in human milk. Caution should be exercised when not significantly induce neoplasms in mice ------DOSAGE AND ADMINISTRATION------contact Bausch & Lomb Incorporated. at 1-800-323- BEPREVE (bepotastine besilate ophthalmic receiving a nominal dose of up to 200 mg/kg/day Instill one drop into the affected eye(s) twice a day 0000, or FDA at 1-800-FDA-1088 or www.fda.gov/ solution) 1.5% is administered to a nursing woman. for 21 months or rats receiving a nominal dose of (BID). (2) medwatch. up to 97 mg/kg/day for 24 months. These dose 8.4 Pediatric Use ------DOSAGE FORMS AND STRENGTHS------See 17 for PATIENT COUNSELING INFORMATION levels represent systemic exposures Safety and efficacy of BEPREVE (bepotastine Solution containing bepotastine besilate, 1.5%. (3) approximating 350 and 200 times that achieved besilate ophthalmic solution) 1.5% have not been with human topical ocular use. The no observable ------CONTRAINDICATIONS------Revised: 10/2012 established in pediatric patients under 2 years of adverse effect levels for bepotastine besilate Hypersensitivity to any component of this product. (4) age. Efficacy in pediatric patients under 10 years based on nominal dose levels in carcinogenicity of age was extrapolated from clinical trials tests were 18.7 to 19.9 mg/kg/day in mice and 9.6 conducted in pediatric patients greater than 10 FULL PRESCRIBING INFORMATION: 11 DESCRIPTION to 9.8 mg/kg/day in rats (representing exposure years of age and from adults. CONTENTS* 12 CLINICAL PHARMACOLOGY margins of approximately 60 and 20 times the 1 INDICATIONS AND USAGE 12.1 Mechanism of Action 8.5 Geriatric Use systemic exposure anticipated for topical ocular 2 DOSAGE AND ADMINISTRATION 12.3 Pharmacokinetics No overall difference in safety or effectiveness has use in humans). 3 DOSAGE FORMS AND STRENGTHS 13 NONCLINICAL TOXICOLOGY been observed between elderly and younger patients. 4 CONTRAINDICATIONS 13.1 Carcinogenesis, Mutagenesis and There was no evidence of genotoxicity in the 11 DESCRIPTION 5 WARNINGS AND PRECAUTIONS Impairment of Fertility Ames test, in CHO cells (chromosome aberrations), BEPREVE (bepotastine besilate ophthalmic 5.1 Contamination of Tip and Solution 14 CLINICAL STUDIES in mouse hepatocytes (unscheduled DNA solution) 1.5% is a sterile, topically administered 5.2 Contact Lens Use 16 HOW SUPPLIED/STORAGE AND HANDLING synthesis), or in the mouse micronucleus test. drug for ophthalmic use. Each mL of BEPREVE 5.3 Topical Ophthalmic Use Only 17 PATIENT COUNSELING INFORMATION When oral bepotastine was administered to male contains 15 mg bepotastine besilate. 6 ADVERSE REACTIONS 17.1 Topical Ophthalmic Use Only and female rats at doses up to 1,000 mg/kg/day, Bepotastine besilate is designated chemically as 6.1 Clinical Trial Experience 17.2 Sterility of Dropper Tip there was a slight reduction in fertility index and (+) -4-[[(S)-p-chloro-alpha -2-pyridylbenzyl]oxy]-1- 6.2 Post-Marketing Experience 17.3 Concomitant Use of Contact Lenses surviving fetuses. Infertility was not seen in rats piperidine butyric acid monobenzenesulfonate. 8 USE IN SPECIFIC POPULATIONS given 200 mg/kg/day oral bepotastine besilate * Sections or subsections omitted from the full The chemical structure for bepotastine besilate is: 8.1 Pregnancy (approximately 3,300 times the systemic prescribing information are not listed 8.3 Nursing Mothers concentration anticipated for topical ocular use 8.4 Pediatric Use in humans). 8.5 Geriatric Use 14 CLINICAL STUDIES FULL PRESCRIBING INFORMATION The most common reported adverse reaction Clinical efficacy was evaluated in 2 conjunctival occurring in approximately 25% of subjects was a allergen challenge (CAC) studies (237 patients). 1 INDICATIONS AND USAGE mild taste following instillation. Other adverse BEPREVE (bepotastine besilate ophthalmic BEPREVE® (bepotastine besilate ophthalmic reactions occurring in 2-5% of subjects were eye Bepotastine besilate is a white or pale yellowish solution) 1.5% was more effective than its vehicle solution) 1.5% is a histamine H receptor antagonist 1 crystalline powder. The molecular weight of for relieving ocular itching induced by an ocular irritation, headache, and nasopharyngitis. ® indicated for the treatment of itching associated bepotastine besilate is 547.06 daltons. BEPREVE allergen challenge, both at a CAC 15 minutes post- with signs and symptoms of allergic conjunctivitis. 6.2 Post Marketing Experience ophthalmic solution is supplied as a sterile, dosing and a CAC 8 hours post dosing of BEPREVE. Hypersensitivity reactions have been reported 2 DOSAGE AND ADMINISTRATION aqueous 1.5% solution, with a pH of 6.8. rarely during the post-marketing use of BEPREVE. The safety of BEPREVE was evaluated in a Instill one drop of BEPREVE into the affected The osmolality of BEPREVE (bepotastine besilate Because these reactions are reported voluntarily randomized clinical study of 861 subjects over a eye(s) twice a day (BID). ophthalmic solution) 1.5% is approximately from a population of unknown size, it is not 290 mOsm/kg. period of 6 weeks. 3 DOSAGE FORMS AND STRENGTHS always possible to reliably estimate their Each mL of BEPREVE® (bepotastine besilate 16 HOW SUPPLIED/STORAGE AND HANDLING Topical ophthalmic solution containing frequency or establish a casual relationship to ophthalmic solution) 1.5% contains: BEPREVE® (bepotastine besilate ophthalmic bepotastine besilate 1.5%. drug exposure. The hypersensitivity reactions Active: Bepotastine besilate 15 mg (equivalent to solution) 1.5% is supplied in a white low density include itching, body rash, and swelling of lips, 4 CONTRAINDICATIONS 10.7 mg bepotastine) polyethylene plastic squeeze bottle with a white tongue and/or throat. Bepreve is contraindicated in patients with a Preservative: benzalkonium chloride 0.005% controlled dropper tip and a white polypropylene history of hypersensitivity reactions to bepotastine 8 USE IN SPECIFIC POPULATIONS Inactives: monobasic sodium phosphate cap in the following size: or any of the other ingredients [see Adverse 8.1 Pregnancy dihydrate, sodium chloride, sodium hydroxide to 5 mL (NDC 24208-629-02) Reactions (6.2)]. Pregnancy Category C: Teratogenicity studies adjust pH, and water for injection, USP. 10 mL (NDC 24208-629-01) have been performed in animals. Bepotastine 5 WARNINGS AND PRECAUTIONS 12 CLINICAL PHARMACOLOGY STORAGE besilate was not found to be teratogenic in rats 5.1 Contamination of Tip and Solution 12.1 Mechanism of Action Store at 15º – 25ºC (59º – 77ºF). during organogenesis and fetal development at To minimize contaminating the dropper tip and Bepotastine is a topically active, direct H1- oral doses up to 200 mg/kg/day (representing a 17 PATIENT COUNSELING INFORMATION solution, care should be taken not to touch the receptor antagonist and an inhibitor of the release systemic concentration approximately 3,300 times 17.1 Topical Ophthalmic Use Only eyelids or surrounding areas with the dropper tip of histamine from mast cells. that anticipated for topical ocular use in humans), For topical ophthalmic administration only. of the bottle. Keep bottle tightly closed when not 12.3 Pharmacokinetics but did show some potential for causing skeletal 17.2 Sterility of Dropper Tip in use. Absorption: The extent of systemic exposure to abnormalities at 1,000 mg/kg/day. There were no Patients should be advised to not touch dropper tip bepotastine following topical ophthalmic 5.2 Contact Lens Use teratogenic effects seen in rabbits at oral doses to any surface, as this may contaminate the contents. Patients should be advised not to wear a contact up to 500 mg/kg/day given during organogenesis administration of bepotastine besilate 1% and 1.5% lens if their eye is red. BEPREVE should not be and fetal development (>13,000 times the dose in ophthalmic solutions was evaluated in 12 healthy 17.3 Concomitant Use of Contact Lenses used to treat contact lens-related irritation. humans on a mg/kg basis). Evidence of infertility adults. Following one drop of 1% or 1.5% bepotastine Patients should be advised not to wear a contact was seen in rats given oral bepotastine besilate besilate ophthalmic solution to both eyes four times lens if their eye is red. Patients should be advised BEPREVE should not be instilled while wearing 1,000 mg/kg/day; however, no evidence of daily (QID) for seven days, bepotastine plasma that BEPREVE should not be used to treat contact contact lenses. Remove contact lenses prior to infertility was observed in rats given 200 mg/kg/ concentrations peaked at approximately one to two lens-related irritation. instillation of BEPREVE. The preservative in hours post-instillation. Maximum plasma day (approximately 3,300 times the topical ocular Patients should also be advised to remove BEPREVE, benzalkonium chloride, may be concentration for the 1% and 1.5% strengths were use in humans). The concentration of radio- contact lenses prior to instillation of BEPREVE. absorbed by soft contact lenses. Lenses may be 5.1 ± 2.5 ng/mL and 7.3 ± 1.9 ng/mL, respectively. labeled bepotastine besilate was similar in fetal The preservative in BEPREVE, benzalkonium reinserted after 10 minutes following Plasma concentration at 24 hours post-instillation liver and maternal blood plasma following a single chloride, may be absorbed by soft contact lenses. administration of BEPREVE. were below the quantifiable limit (2 ng/mL) in 11/12 3 mg/kg oral dose. The concentration in other Lenses may be reinserted after 10 minutes subjects in the two dose groups. 5.3 Topical Ophthalmic Use Only fetal tissues was one-third to one-tenth the following administration of BEPREVE. BEPREVE is for topical ophthalmic use only. concentration in maternal blood plasma. Distribution: The extent of protein binding of Manufactured by: Bausch & Lomb Incorporated bepotastine is approximately 55% and 6 ADVERSE REACTIONS An increase in stillborns and decreased growth Tampa, FL 33637 independent of bepotastine concentration. 6.1 Clinical Trials Experience and development were observed in pups born Under license from: Because clinical trials are conducted under from rats given oral doses of 1,000 mg/kg/day Metabolism: In vitro metabolism studies with human Senju Pharmaceutical Co., Ltd. widely varying conditions, adverse reaction rates during perinatal and lactation periods. There liver microsomes demonstrated that bepotastine is Osaka, Japan 541-0046 observed in the clinical trials of a drug cannot be were no observed effects in rats treated with minimally metabolized by CYP450 isozymes. ®/TM are trademarks of Bausch & Lomb directly compared to rates in the clinical trials of 100 mg/kg/day. Incorporated or its affiliates another drug and may not reflect the rates In vitro studies demonstrated that bepotastine There are no adequate and well-controlled © 2012 Bausch & Lomb Incorporated. observed in clinical practice. besilate does not inhibit the metabolism of various studies of bepotastine besilate in pregnant US/BEP/13/0028 4/13

RRO0214_BLO0214_BL BepreveBepreve PI.inddPI.indd 1 11/16/14/16/14 9:539:53 AMAM Welcome

CE Gives Us a Vision for the Future

s optometrists, we are practicing at With this in mind, Review of Optometry Aone of the most exciting times in the created this comprehensive annual guide history of our profession. Our legislative to all available educational courses. eff orts successfully transformed the In 2016, you’ll have over 200 learning delivery of eye care in the United States, opportunities to choose from. You’ll fi nd enabling optometrists to serve the public that some lectures are happening just good by satisfying the unmet patient across town, while others are taking care needs of a population that is both place literally across the globe. Our 2016 growing and graying. Simultaneously, an Conference Planner details meetings explosion of innovation has given us new that range from state optometric society medical drugs and devices to improve seminars to “destination CE” events in eye health and vision that are rightly far-fl ung venues around the world—and considered modern marvels. everywhere in between. The strides we have made as a We sincerely hope this guide helps you profession in recent years are truly plan your calendars for the upcoming year remarkable. Optometrists continue so that you can take advantage of the to be recognized as the essential collective knowledge of our profession primary eye care provider in this and bring it back home to incorporate country. But with this responsibility into your practice. Our patients’ vision comes another: the need to ensure we and quality of life are of the utmost are best trained and equipped to provide importance to each of us. That’s why it is exceptional care for our patients in the critical that we continue to stay up to date ever-changing optometric landscape. on the latest advances in our profession. Continuing education events give Review of Optometry also makes us what we need most in this eff ort: continuing education a priority—in print, access and answers. CE provides us the online and at our own live events—and knowledge and the opportunity to share we are pleased to once again off er the and connect with each other, to seek the “New Technologies and Treatments counsel of experts while sharing our own in Vision Care” meeting series in 2016. unique experiences in the exam room These meetings will be held in several with colleagues and friends. locations across the country on topics Of course, CE options abound. As such as dry eye, surgical comanagement busy clinicians, it’s often challenging to and glaucoma. I look forward to seeing keep up with the multitude of classes you at a meeting in 2016! and meetings and choose the lectures and locales best suited to our needs. Sincerely, It’s both exciting and perhaps a little bit overwhelming to see just how many Paul Karpecki, OD learning opportunities are available to us. Chief Clinical Editor

4 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 4 12/3/15 12:23 PM Down, Boy. Help Tame Postoperative Ocular Inflammation and Pain With LOTEMAX® GEL Indication LOTEMAX® GEL (loteprednol etabonate ophthalmic gel) 0.5% is indicated for the treatment of post-operative infl ammation and pain following ocular surgery. Important Safety Information about LOTEMAX® GEL • LOTEMAX ® GEL is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures. • Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fields of vision. If this product is used for 10 days or longer, IOP should be monitored. • Use of corticosteroids may result in posterior subcapsular cataract formation. • Use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation and occurrence of perforations in those with diseases causing corneal and scleral thinning. The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnification, and where appropriate, fluorescein staining. • Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infection. In acute purulent conditions, steroids may mask infection or enhance existing infection. • Use of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and exacerbate the severity of many viral infections of the eye (including herpes simplex). • Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use. • Patients should not wear contact lenses when using LOTEMAX® GEL. • The most common ocular adverse drug reactions reported were anterior chamber inflammation (5%), eye pain (2%) and foreign body sensation (2%). Please see brief summary of Prescribing Information on adjacent page. ®/™ are trademarks of Bausch & Lomb Incorporated or its affi liates. © 2015 Bausch & Lomb Incorporated. All rights reserved. Printed in USA. US/LGX/15/0041(1)

RO1015_BL Lotemax.indd 1 9/15/15 2:24 PM BRIEF SUMMARY OF PRESCRIBING INFORMATION ossification) and teratogenic (increased incidence of meningocele, abnormal This Brief Summary does not include all the information needed to left common carotid artery, and limb flexures) when administered orally prescribe Lotemax Gel safely and effectively. See full prescribing to rabbits during organogenesis at a dose of 3 mg/kg/day (35 times information for Lotemax Gel. the maximum daily clinical dose), a dose which caused no maternal toxicity. The no-observed-effect-level (NOEL) for these effects was 0.5 mg/kg/day (6 times the maximum daily clinical dose). Oral treatment (loteprednol etabonate ophthalmic gel) 0.5% Lotemax of rats during organogenesis resulted in teratogenicity (absent innominate Rx only artery at ≥5 mg/kg/day doses, and cleft palate and umbilical hernia Initial Rx Approval: 1998 at ≥50 mg/kg/day) and embryotoxicity (increased post-implantation losses at 100 mg/kg/day and decreased fetal body weight and skeletal INDICATIONS AND USAGE ossification with ≥50 mg/kg/day). Treatment of rats with 0.5 mg/kg/day LOTEMAX is a corticosteroid indicated for the treatment of post-operative (6 times the maximum clinical dose) during organogenesis did not result inflammation and pain following ocular surgery. in any reproductive toxicity. Loteprednol etabonate was maternally toxic DOSAGE AND ADMINISTRATION (significantly reduced body weight gain during treatment) when administered Invert closed bottle and shake once to fill tip before instilling drops. to pregnant rats during organogenesis at doses of ≥5 mg/kg/day. Apply one to two drops of LOTEMAX into the conjunctival sac of the affected Oral exposure of female rats to 50 mg/kg/day of loteprednol etabonate from eye four times daily beginning the day after surgery and continuing the start of the fetal period through the end of lactation, a maternally toxic throughout the first 2 weeks of the post-operative period. treatment regimen (significantly decreased body weight gain), gave rise to decreased growth and survival, and retarded development in the offspring CONTRAINDICATIONS during lactation; the NOEL for these effects was 5 mg/kg/day. Loteprednol LOTEMAX, as with other ophthalmic corticosteroids, is contraindicated in etabonate had no effect on the duration of gestation or parturition when most viral diseases of the cornea and conjunctiva including epithelial herpes administered orally to pregnant rats at doses up to 50 mg/kg/day during the simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in fetal period. mycobacterial infection of the eye and fungal diseases of ocular structures. There are no adequate and well controlled studies in pregnant women. WARNINGS AND PRECAUTIONS LOTEMAX should be used during pregnancy only if the potential benefit Intraocular Pressure (IOP) Increase justifies the potential risk to the fetus. Prolonged use of corticosteroids may result in glaucoma with damage to the Nursing Mothers optic nerve, defects in visual acuity and fields of vision. Steroids should be It is not known whether topical ophthalmic administration of corticosteroids used with caution in the presence of glaucoma. If this product is used for 10 could result in sufficient systemic absorption to produce detectable quantities days or longer, intraocular pressure should be monitored. in human milk. Systemic steroids appear in human milk and could suppress Cataracts growth, interfere with endogenous corticosteroid production, or cause other Use of corticosteroids may result in posterior subcapsular cataract formation. untoward effects. Caution should be exercised when LOTEMAX is administered Delayed Healing to a nursing woman. The use of steroids after cataract surgery may delay healing and increase the Pediatric Use incidence of bleb formation. In those diseases causing thinning of the cornea Safety and effectiveness in pediatric patients have not been established. or sclera, perforations have been known to occur with the use of topical Geriatric Use steroids. The initial prescription and renewal of the medication order should No overall differences in safety and effectiveness have been observed be made by a physician only after examination of the patient with the aid between elderly and younger patients. of magnification such as slit lamp biomicroscopy and, where appropriate, NONCLINICAL TOXICOLOGY fluorescein staining. Carcinogenesis, Mutagenesis, Impairment Of Fertility Bacterial Infections Long-term animal studies have not been conducted to evaluate the Prolonged use of corticosteroids may suppress the host response and carcinogenic potential of loteprednol etabonate. Loteprednol etabonate was thus increase the hazard of secondary ocular infections. In acute purulent not genotoxic in vitro in the Ames test, the mouse lymphoma tk assay, or in conditions of the eye, steroids may mask infection or enhance existing a chromosome aberration test in human lymphocytes, or in vivo in the single infection. dose mouse micronucleus assay. Treatment of male and female rats with up Viral Infections to 50 mg/kg/day and 25 mg/kg/day of loteprednol etabonate, respectively, Employment of a corticosteroid medication in the treatment of patients with (600 and 300 times the maximum clinical dose, respectively) prior to and a history of herpes simplex requires great caution. Use of ocular steroids may during mating did not impair fertility in either gender. prolong the course and may exacerbate the severity of many viral infections PATIENT COUNSELING INFORMATION of the eye (including herpes simplex). Administration Fungal Infections Invert closed bottle and shake once to fill tip before instilling drops. Fungal infections of the cornea are particularly prone to develop Risk of Contamination coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been Patients should be advised not to allow the dropper tip to touch any surface, used or is in use. Fungal cultures should be taken when appropriate. as this may contaminate the gel. Contact Lens Wear Contact Lens Wear Patients should not wear contact lenses during their course of therapy with Patients should be advised not to wear contact lenses when using LOTEMAX. LOTEMAX. Risk of Secondary Infection ADVERSE REACTIONS If pain develops, redness, itching or inflammation becomes aggravated, the Adverse reactions associated with ophthalmic steroids include elevated patient should be advised to consult a physician. intraocular pressure, which may be associated with infrequent optic nerve damage, visual acuity and field defects, posterior subcapsular cataract Bausch & Lomb Incorporated formation, delayed wound healing and secondary ocular infection from Tampa, Florida 33637 USA pathogens including herpes simplex, and perforation of the globe where US Patent No. 5,800,807 there is thinning of the cornea or sclera. ©Bausch & Lomb Incorporated The most common adverse drug reactions reported were anterior chamber inflammation (5%), eye pain (2%), and foreign body sensation (2%). ®/™ are trademarks of Bausch & Lomb Incorporated or its affiliates. USE IN SPECIFIC POPULATIONS Pregnancy US/LGX/15/0042 Teratogenic Effects: Pregnancy Category C. Based on 9269100-9269200 Revised: 9/2012 Loteprednol etabonate has been shown to be embryotoxic (delayed

RRO1015_BLO1015_BL LLotemaxotemax PI.inddPI.indd 1 99/15/15/15/15 2:292:29 PMPM Table of Contents

4 ...... Welcome 18 Atlanta 8 ...... January SECO

14 ...... February

23 ...... March

26 ...... April

36 ...... May

38 ...... June

44 ...... July 40 Boston 48 ...... August AOA 64 50...... September Anaheim Academy 58 ...... October

63 ...... November

6 6 ...... December

DIGITAL EDITION — Look online at www.reviewofoptometry.com/supplements for a digital edition of this publication, which contains active, “clickable” links to the email addresses and web sites mentioned throughout.

Lecture topics scheduled to be EDUCATION TOPICS discussed at educational events CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders are denoted by the appearance AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery of the icons at right, based on AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision information known at press time. BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease Conference agendas are subject CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology to change. Please contact the CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis meeting organizers for updated CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy information.

REVIEW OF OPTOMETRY DECEMBER 15, 2015 7

000_1215_ceconference_final.indd 7 12/3/15 12:24 PM January

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

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3456789 The FIrst Annual Pacific U. Glaucoma Optometric Symposium 2016 Convention 2016 Coding Update Principles of Prescribing ECA Annual Conference

10 11 12 13 14 15 16 Principles of Missouri OA Low Vision Grand ICO Resident Grand Kraskin Invitational Prescribing 2016 Legislative Rounds – Glaucoma Rounds Skeffington Symp. Conference ECA Annual Berkeley Practicum Conference Gold Coast Educational Retreat

17 18 19 20 21 22 23 Pacific University 2016 Island Eyes Conference Kraskin Invitational Skeffington Symposium Global Specialty Lens Symposium Berkeley Practicum TCOS Winter CE 2016 Gold Coast RSO Glaucoma Educational Retreat Symposium Illinois OA Winter CE

24 25 26 27 28 29 30 Global Specialty OEP Foundation ABI/TBI – Diagnosis, Mgmt. Lens Symposium and Treatment of Brain Injury Patients RSO Glaucoma Georgia Optometric Symposium Association Super CE Illinois OA Winter CE MBKU & Stein-Doheny Annual Symposium

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OEP Foundation ABI/TBI – Diagnosis, Mgmt. & Treatment of Brain Injury Patients Virginia OA One-Day CE Conference

8 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 8 112/3/152/3/15 12:3012:30 PMPM Jan. 8, Fort Lauderdale KEY FACULTY: Robert Hohendorf Jan. 15, Chicago The First Annual Optometric CE HOURS: 12 ICO Resident Grand Rounds Convention LOCATION: 2080 Appleby Line, HOST: Illinois College of Optometry HOST: America Health Innovations Ste. E6 CE HOURS: 4 KEY FACULTY: Larry Lampert, Mitra CONTACT: Karen Ruder LOCATION: Illinois College of Sehi, Natalia Villate, Corry Collier [email protected] Optometry, 3241 S Michigan Ave. CE HOURS: Total: 8, maximum per 410-561-3791 CONTACT: Elizabeth Grantner OD: 2 www.oepf.org/oepf_calendar [email protected] LOCATION: Great Fort Lauderdale & BV DS 312-949-7426 Broward Convention Center, www.ico.edu/alumni/continuing- 1950 Eisenhower Blvd. Jan. 9-10, Williamsburg, VA education CONTACT: Waseem Khan ECA Annual Conference AL AM BV CM CL CD CS CT DE EL GL waseem@americahealthinnovations. HOST: EyeCare Associates LT NO NT IN PH RE SV SD TE UV com KEY FACULTY: Marc Myers, Andrew 561-316-0790 Gurwood Jan. 16-17, Fort Lauderdale www.ahieducation.com CE HOURS: 12 Gold Coast Educational Retreat CD GL RE SV LOCATION: Doubletree by Hilton, HOST: Broward County Optometric 50 Kingsmill Rd. Association Jan. 9, Woodinville, WA CONTACT: Linda Cavazos KEY FACULTY: Randall Thomas, Ron Glaucoma Symposium 2016 [email protected] Melton, Tim Murray, Roger Prouty, HOST: Pacifi c University College of 804-356-5165 Cory Collier, Joseph Sowka, Joseph Optometry More information available through Pizzimenti KEY FACULTY: Howard Barnebey, the Facebook account “Eye Care CE HOURS: 17 Murray Fingeret Associates of Virginia” LOCATION: Hyatt Regency Pier 66, CE HOURS: 7 CS GL IN RE 2301 SE 17th St. LOCATION: Willows Lodge, CONTACT: Rachell Snell, Brandon 14580 NE 145th St. Jan. 11, Jeff erson City, MO Cornish CONTACT: Martina Fredericks 2016 Legislative Conference [email protected] frederim@pacifi cu.edu HOST: Missouri Optometric browardeyes.org 503-352-2207 Association AL CL CD DB DE EL GL NO NT IN PH www.pacifi cu.edu/future-graduate- KEY FACULTY: Alan Cleinman PM RE SD TE UV professional/colleges/college- CE HOURS: 3 optometry/continuing-education LOCATION: Capitol Plaza Hotel, Jan. 16-18, Bethesda, MD GL 415 W McCarty St. Kraskin Invitational Skeffi ngton CONTACT: Lee Ann Barrett Symposium on Vision (KISS) Jan. 9, Little Rock, AK [email protected] HOST: Optometric Extension Program 2016 Coding Update 573-635-6151 Foundation (OEPF) HOST: Arkansas Optometric www.moeyecare.org KEY FACULTY: Multiple presenters Association PM CE HOURS: 19 KEY FACULTY: John McGreal LOCATION: Hyatt Regency Bethesda, CE HOURS: 5 Jan. 14, Wichita, KS One Bethesda Metro Center, LOCATION: Embassy Suites Little Low Vision Grand Rounds – 7400 Wisconsin Ave. Rock, 11301 Financial Centre Parkway Glaucoma and Tube-Shunt Surgery CONTACT: Jeff rey Kraskin CONTACT: Vicki Farmer HOST: Envision University [email protected] [email protected] KEY FACULTY: Anita Campbell 202-363-4450 501-661-7675 CE HOURS: 2 www.skeffi ngtonsymposium.org arkansasoptometric.org LOCATION: Envision, 610 N. Main St. AM BV NO NT PE SV VT PM CONTACT: Michael Epp [email protected] Jan. 16-18, Berkeley, CA Jan. 9-10, Burlington, Ontario 326-440-1515 Berkeley Practicum — 27th Annual Principles of Prescribing www.envisionuniversity.org HOST: University of California, HOST: Patricia Fink and OEP Fdn. GL Berkeley, School of Optometry KEY FACULTY: Robert Lustig, John

EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders McGreal, Jr., Robert Wooldridge, AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Blair Lonsberry, Danica Marrelli, Lorre AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision Henderson BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease CE HOURS: 20 CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology LOCATION: DoubleTree Hotel, CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis Berkeley Marina, 200 Marina Blvd. CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy CONTACT: Danni Peck [email protected]

REVIEW OF OPTOMETRY DECEMBER 15, 2015 9

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 9 112/3/152/3/15 12:3112:31 PMPM 800-827-2163 http://optometry.berkeley.edu/ce/ berkeley-practicum EL GL NO NT IN RE SD TE

Jan. 17, Wheeling, IL IOA Winter CE Series HOST: Illinois Optometric Association KEY FACULTY: Len Messner APRIL 7-10, MAY 20-22, JUNE 9-12, OCTOBER 6-8, CE HOURS: 6 regular or TQ SAN DIEGO SAN ANTONIO BERMUDA PHILADELPHIA LOCATION: Westin Chicago North Shore, 610 N. Milwaukee Ave. Announcing Review of Optometry’s “New Technologies CONTACT: Charlene Marsh and Treatments in Vision Care” Series for 2016 [email protected] 217-525-8012 n recent years, breakthroughs in The educational faculty welcome www.ioaweb.org Iclinical care have come at lightning interaction with attendees, Dr. Karpecki speed. While these advances off er new says. While traditional learning hap- NO opportunities for optometrists, fi guring pens in the lecture hall, some of the out how to apply them day-to-day can best education actually occurs during Jan. 17-23, Lahaina, Maui, HI seem challenging. the receptions and breaks, where the 2016 Island Eyes Conference To help, Review of Optometry will presenters and attendees have the op- HOST: Pacifi c University College of once again conduct its “New Technolo- portunity to talk one on one, he adds. Optometry gies and Treatments in Vision Care” What sets these meetings apart is KEY FACULTY: Denise Goodwin, meeting series in 2016. The events pro- their interactive and intimate nature, Nathan Lighthizer, Leo Skorin, Stanley vide a relaxed and collegial atmosphere which bringd attendees back year after Teplick, Samuel Kim that encourages communication and year, Dr. Karpecki says. In fact, more CE HOURS: 29 learning, bringing together clinicians, than 90% of doctors who have gone to LOCATION: Sheraton Maui Resort, researchers and industry partners for previous meetings have returned the 2605 Ka’anapali Parkway a truly unique educational experience. next year, according to recent surveys. CONTACT: Jeanne Oliver Nationally known experts will off er “The attendees, faculty, sponsors insights into the latest ophthalmic inno- and even the fabulous locations all con- jeanne@pacifi cu.edu vations and help you learn to success- tribute to making these meetings some 503-352-2740 fully integrate them into your practice. of the most enjoyable educational www.pacifi cu.edu/islandeyes The meetings will delve into the experiences in the country,” he says. CM CD CS CT DE GL NO IN TE UV latest disruptive eye care innovations The 2016 NT&T meeting schedule is that will aff ect your patients and help as follows: Jan. 21-24, Las Vegas position your practice for a very bright • April 7-10, San Diego. Taking place Global Specialty Lens Symposium future, says Review of Optometry Chief at the famous Hotel del Coronado, the HOST: Contact Lens Spectrum Clinical Editor and meeting chair Paul fi rst NT&T event of 2016 will be held in KEY FACULTY: National and Karpecki, OD. Topics will cover recent conjunction with the annual educa- international experts from over 30 advances in dry eye, eyelid disease, tional symposium of the Optometric countries glaucoma, ocular infections, diabetes Cornea, Cataract and Refractive Soci- CE HOURS: 30 management, retinal disease, pharma- ety (OCCRS). This unique joint meeting LOCATION: Caesars Palace, cology and ocular surgery. of NT&T and OCCRS will off er up to 28 3570 S. Las Vegas Blvd. “The hands-on workshops in glau- CE credit hours. coma and dry eye will give you all the • May 20-22, San Antonio. This CONTACT: Maureen Trusky tools necessary to start or enhance meeting will take place at the San An- [email protected] these very critical components of your tonio Marriott Rivercenter. A total of 19 gslsymposium.com practice,” says Dr. Karpecki. “These CE credit hours will be available. CL workshops have been so eff ective for • June 9-12, Hamilton, Bermuda. attendees in achieving a higher level This meeting will be held at the Hamil- Jan. 23, Ventura, CA of patient care that we’re likely to add ton Princess & Beach Club, where 14 CE TCOS Winter CE 2016 new hands-on workshops in the areas hours can be earned. HOST: Tri-County Optometric Society of retinal disease and surgical coman- • October 6-8, Philadelphia. The city KEY FACULTY: Ron Melton, Randall agement.” The workshops are included of brotherly love will host this meeting Thomas in the cost of registration. at the Philadelphia Marriott Downtown, CE HOURS: 5 Due to the success of the meetings, with 19 CE credit hours available. LOCATION: Ventura Beach Marriott, registration fees have not increased For more information, contact Lois 2055 E. Harbor Blvd. in over 10 years. “The New Technolo- DiDomenico at reviewmeetings@ gies and Treatments in Vision Care jobson.com or 866-658-1772, or CONTACT: Morgan A. Ruiz series are probably the only meetings check www.reviewofoptometry.com/ [email protected] that have accomplished that feat,” Dr. continuing_education for updates 805-689-8671 Karpecki adds. throughout the year. www.tcosvision.org CM CS EL PH RE RS

10 REVIEW OF OPTOMETRY DECEMBER 15, 2015

FINAL LAYOUT DEC 8.indd 10 12/8/15 1:59 PM ALREX®: TREATS THE ITCH AND MORE. SHORT-TERM TREATMENT FOR THE FULL SPECTRUM OF SAC* SIGNS AND SYMPTOMS1-3

*Seasonal allergic conjunctivitis. INDICATION ALREX® (loteprednol etabonate ophthalmic suspension) is indicated for the temporary relief of the signs and symptoms of seasonal allergic conjunctivitis. IMPORTANT SAFETY INFORMATION ALREX® is contraindicated in most viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of the ocular structures. ALREX® is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids. Prolonged use of ALREX® is associated with several warnings and precautions, including glaucoma with optic nerve damage, defects in visual acuity, cataract formation, secondary ocular infections, and exacerbation or prolongation of viral ocular infections (including herpes simplex). If this product is used for 10 days or longer, intraocular pressure should be monitored. The initial prescription and renewal of the medication order beyond 14 days should be made by a physician only after reexamination of the patient with the aid of magnifi cation. Fungal infections of the cornea may develop with prolonged use of corticosteroids. Ocular adverse reactions occurring in 5-15% of patients treated with loteprednol etabonate ophthalmic suspension (0.2%-0.5%) in clinical studies included abnormal vision/blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, infection, and photophobia. Please see brief summary of full Prescribing Information on the following page. References: 1. ALREX [package insert]. Tampa, FL: Bausch & Lomb Incorporated; 2013. 2. Dell SJ, Lowry GM, Northcutt JA, Howes J, Novack GD, Hart K. A randomized, double-masked, placebo-controlled parallel study of 0.2% loteprednol etabonate in patients with seasonal allergic conjunctivitis. J Allergy Clin Immunol. 1998;102(2):251-255. 3. Shulman DG, Lothringer LL, Rubin JM, et al. A randomized, double-masked, placebo-controlled parallel study of loteprednol etabonate 0.2% in patients with seasonal allergic conjunctivitis. Ophthalmology. 1999;106(2):362-369.

ALREX is a trademark of Bausch & Lomb Incorporated or its affi liates. ©Bausch & Lomb Incorporated. US/ALX/15/0001a

RO0515_BL Alrex.indd 1 4/22/15 2:24 PM BRIEF SUMMARY OF PRESCRIBING INFORMATION Pregnancy: Teratogenic effects: Pregnancy Category C. Loteprednol etabonate has been shown to be embryotoxic (delayed ossification) This Brief Summary does not include all the information needed to and teratogenic (increased incidence of meningocele, abnormal left use Alrex® (loteprednol etabonate ophthalmic suspension 0.2%) common carotid artery, and limb flexures) when administered orally safely and effectively. See full prescribing information for Alrex. to rabbits during organogenesis at a dose of 3 mg/kg/day (85 times the maximum daily clinical dose), a dose which caused no maternal toxicity. The no-observed-effect-level (NOEL) for these effects was Alrex® 0.5 mg/kg/day (15 times the maximum daily clinical dose). Oral loteprednol etabonate treatment of rats during organogenesis resulted in teratogenicity ophthalmic suspension 0.2% (absent innominate artery at ≥5 mg/kg/day doses, and cleft palate and umbilical hernia at ≥50 mg/kg/day) and embryotoxicity (increased Sterile Ophthalmic Suspension postimplantation losses at 100 mg/kg/day and decreased fetal body weight and skeletal ossification with ≥50 mg/kg/day). Treatment of Rx only rats with 0.5 mg/kg/day (15 times the maximum clinical dose) during organogenesis did not result in any reproductive toxicity. Loteprednol INDICATIONS AND USAGE etabonate was maternally toxic (significantly reduced body weight ALREX Ophthalmic Suspension is indicated for the temporary relief of the gain during treatment) when administered to pregnant rats during signs and symptoms of seasonal allergic conjunctivitis. organogenesis at doses of ≥5 mg/kg/day. CONTRAINDICATIONS Oral exposure of female rats to 50 mg/kg/day of loteprednol etabonate ALREX, as with other ophthalmic corticosteroids, is contraindicated in from the start of the fetal period through the end of lactation, a most viral diseases of the cornea and conjunctiva including epithelial maternally toxic treatment regimen (significantly decreased body herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and weight gain), gave rise to decreased growth and survival, and retarded also in mycobacterial infection of the eye and fungal diseases of ocular development in the offspring during lactation; the NOEL for these effects structures. ALREX is also contraindicated in individuals with known or was 5 mg/kg/day. Loteprednol etabonate had no effect on the duration suspected hypersensitivity to any of the ingredients of this preparation of gestation or parturition when administered orally to pregnant rats at and to other corticosteroids. doses up to 50 mg/kg/day during the fetal period. WARNINGS There are no adequate and well controlled studies in pregnant women. Prolonged use of corticosteroids may result in glaucoma with damage ALREX Ophthalmic Suspension should be used during pregnancy only if to the optic nerve, defects in visual acuity and fields of vision, and in the potential benefit justifies the potential risk to the fetus. posterior subcapsular cataract formation. Steroids should be used with Nursing Mothers: It is not known whether topical ophthalmic caution in the presence of glaucoma. administration of corticosteroids could result in sufficient systemic Prolonged use of corticosteroids may suppress the host response and absorption to produce detectable quantities in human milk. Systemic thus increase the hazard of secondary ocular infections. In those diseases steroids appear in human milk and could suppress growth, interfere with causing thinning of the cornea or sclera, perforations have been known endogenous corticosteroid production, or cause other untoward effects. to occur with the use of topical steroids. In acute purulent conditions of Caution should be exercised when ALREX is administered to a nursing the eye, steroids may mask infection or enhance existing infection. woman. Use of ocular steroids may prolong the course and may exacerbate the Pediatric Use: Safety and effectiveness in pediatric patients have not severity of many viral infections of the eye (including herpes simplex). been established. Employment of a corticosteroid medication in the treatment of patients ADVERSE REACTIONS with a history of herpes simplex requires great caution. Reactions associated with ophthalmic steroids include elevated PRECAUTIONS intraocular pressure, which may be associated with optic nerve damage, General: For ophthalmic use only. The initial prescription and renewal visual acuity and field defects, posterior subcapsular cataract formation, of the medication order beyond 14 days should be made by a physician secondary ocular infection from pathogens including herpes simplex, and only after examination of the patient with the aid of magnification, such perforation of the globe where there is thinning of the cornea or sclera. as slit lamp biomicroscopy and, where appropriate, fluorescein staining. Ocular adverse reactions occurring in 5-15% of patients treated with If signs and symptoms fail to improve after two days, the patient should loteprednol etabonate ophthalmic suspension (0.2% - 0.5%) in clinical be re-evaluated. studies included abnormal vision/blurring, burning on instillation, chemosis, discharge, dry eyes, epiphora, foreign body sensation, itching, If this product is used for 10 days or longer, intraocular pressure should injection, and photophobia. Other ocular adverse reactions occurring in be monitored. less than 5% of patients include conjunctivitis, corneal abnormalities, Fungal infections of the cornea are particularly prone to develop eyelid erythema, keratoconjunctivitis, ocular irritation/pain/discomfort, coincidentally with long-term local steroid application. Fungus invasion papillae, and uveitis. Some of these events were similar to the must be considered in any persistent corneal ulceration where a steroid underlying ocular disease being studied. has been used or is in use. Fungal cultures should be taken when Non-ocular adverse reactions occurred in less than 15% of patients. appropriate. These include headache, rhinitis and pharyngitis. Information for Patients: This product is sterile when packaged. In a summation of controlled, randomized studies of individuals treated Patients should be advised not to allow the dropper tip to touch any for 28 days or longer with loteprednol etabonate, the incidence of surface, as this may contaminate the suspension. If redness or itching significant elevation of intraocular pressure (≥10 mm Hg) was 2% becomes aggravated, the patient should be advised to consult a (15/901) among patients receiving loteprednol etabonate, 7% (11/164) physician. among patients receiving 1% prednisolone acetate and 0.5% (3/583) Patients should be advised not to wear a contact lens if their eye is among patients receiving placebo. Among the smaller group of patients red. ALREX should not be used to treat contact lens related irritation. who were studied with ALREX, the incidence of clinically significant The preservative in ALREX, benzalkonium chloride, may be absorbed by increases in IOP (≥10 mm Hg) was 1% (1/133) with ALREX and 1% soft contact lenses. Patients who wear soft contact lenses and whose (1/135) with placebo. eyes are not red, should be instructed to wait at least ten minutes after instilling ALREX before they insert their contact lenses. DOSAGE AND ADMINISTRATION SHAKE VIGOROUSLY BEFORE USING. Carcinogenesis, Mutagenesis, Impairment of Fertility: Long-term One drop instilled into the affected eye(s) four times daily. animal studies have not been conducted to evaluate the carcinogenic potential of loteprednol etabonate. Loteprednol etabonate was not Revised: August 2013. genotoxic in vitro in the Ames test, the mouse lymphoma tk assay, or in a chromosome aberration test in human lymphocytes, or in vivo Bausch & Lomb Incorporated, Tampa, Florida 33637 in the single dose mouse micronucleus assay. Treatment of male and ©Bausch & Lomb Incorporated female rats with up to 50 mg/kg/day and 25 mg/kg/day of loteprednol Alrex® is a registered trademark of Bausch & Lomb Incorporated etabonate, respectively, (1500 and 750 times the maximum clinical Based on 9007904-9005504 dose, respectively) prior to and during mating did not impair fertility in US/ALX/15/0004 Issued: 02/2015 either gender.

RRO0515_BLO0515_BL AAlrexlrex PPI.inddI.indd 1 44/22/15/22/15 2:262:26 PMPM Jan. 23-24, San Antonio, TX Jan. 24, Fullerton, CA Jan. 30, College Park, GA RSO Glaucoma Symposium The MBKU & Stein-Doheny Annual Georgia Optometric Association HOST: Rosenberg School of Eye Care Symposium Super CE Optometry HOST: SCCO at Marshall B. Ketchum HOST: Georgia Optometric KEY FACULTY: Richard Castillo, University with Stein-Doheny Eye Association Carolyn Majcher, Richard Trevino, Institute at UCLA CE HOURS: 8 Richard Sponsel KEY FACULTY: Barry Weissman LOCATION: Georgia International CE HOURS: Total: 16, maximum per CE HOURS: 8 Convention Center, 2000 Convention OD: 2 LOCATION: Marshall B. Ketchum Center Concourse LOCATION: Rosenberg School of University, 2575 Yorba Linda Blvd. CONTACT: Vanessa Grosso Optometry, 9725 Datapoint CONTACT: Antoinette Smith [email protected] CONTACT: Sandra Fortenberry [email protected]; 714-449-7495 770-961-9866 x-1 [email protected]; 210-283-6856 www.ketchum.edu/index.php/ce www.GOAeyes.com www.uiw.edu/optometry/continuing- AL CD CS CT DB DE EL GL NO RE GL NO IN PH PM SD education GL RS TE Jan. 29-31, Memphis Jan. 31, Glen Allen, VA ABI/TBI – The Diagnosis, Virginia Optometric Association Jan. 24, Rosemont, IL Management and Treatment of IOA Winter CE Series Brain Injury Patients One-Day CE Conference HOST: Illinois Optometric Association HOST: OEP Foundation HOST: Virginia Optometric KEY FACULTY: Paul Karpecki KEY FACULTY: Paul A. Harris Association CE HOURS: 6 regular or TQ CE HOURS: 24 CE HOURS: 4 LOCATION: Hyatt Regency O’Hare, LOCATION: Southern College of LOCATION: Richmond Marriott Short 9300 Bryn Mawr Ave. Optometry, 1245 Madison Ave. Pump, 4240 Dominion Blvd. CONTACT: Charlene Marsh CONTACT: Karen Ruder CONTACT: Bo Keeney, Executive [email protected] [email protected] Director 217-525-8012 410-561-3791 offi [email protected] www.ioaweb.org www.oepf.org/oepf_calendar 804-643-0309 DE BV NO www.thevoa.org

Up to 20 CE Credits (COPE approval pending) ANNUAL WINTER OPHTHALMIC CONFERENCE

TMTM

TM SKIVISION16

NOW A REVIEW OF OPTOMETRY® MEETING OF CLINICAL EXCELLENCE

THE LONGEST RUNNING SKI & CE MEETING IN EYE CARE

FEBRUARY 12 –16, 2016 REGISTRATION THE WESTIN SNOWMASS RESORT COST: $ 100 Elbert Lane INCLUDES Snowmass Village, CO 81615 20 HOURS OF CE, Phone: (970) 923-8200 BREAKFAST, BREAKS Visit www.SkiVision.com for all accommodations and discounted room rates AND RECEPTION 575 3 WAYS TO REGISTER Online: www.SkiVision.com E-mail: [email protected] Phone: 866-730-9257

Approval Pending

000_1215_ceconference_final.indd2016_skiVision_HalfPage.indd 1 13 11/30/1512/3/15 11:3412:51 AMPM February

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

123456 Michigan Optometric Association DOA Winter Thaw Winter Seminar Annual Conference UAB Evening of Education

78910111213 Idaho Optometric OEP Foundation VT/Learning Related Visual Problems Physicians Winter CE Indiana OA Heart of America Contact Lens Society Winter Seminar SkiVision 2016 Innovations in Eye Care Tropical CE Riviera Maya 2016 OAL Mid-Winter CE

14 15 16 17 18 19 20 Western Caribbean Cruise – Innovations in Eye Care Tropical CE Riviera Maya 2016 AEA Cruises Canary Islands Optometric Cruise Seminar SkiVision 2016 Palm Beach Winter Seminar VT/Learning Problems AEA Cruises Eastern Carribean Optometric Heart of America Cruise Seminar Illinois OA Winter CE

21 22 23 24 25 26 27 AEA Cruises Eastern Caribbean Optometric Cruise Seminar AEA Cruises Canary Islands Optometric Cruise Seminar Montana OA Winter Educational Symposium Palm Beach Winter AFOS at SECO 2016 SECO 2016 Seminar Oregon OPA Third Party/Practice Management Seminar ICO Winter CE Neuro-Motor Maturity, Glaucoma Pearls Optimizing Vision Therapy

28 29 Eye Ski Conference (ends Mar. 4) COVD at SECO SECO 2016 Neuro-Motor Maturity, Optimizing Vision Therapy OptoWest South – Newport Beach Illinois OA Winter CE

Feb. 3-4, East Lansing, MI EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders Michigan Optometric Association AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Winter Seminar AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision HOST: Michigan Optometric BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease Association CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology KEY FACULTY: Steven Ferrucci, Marc CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis Bloomenstein CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy CE HOURS: 12

14 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 1414 112/3/152/3/15 12:5112:51 PMPM LOCATION: Kellogg Hotel and Conference Center of Michigan State University, 519 S. Harrison Rd. CONTACT: Amy Root [email protected] 517-482-0616 www.themoa.org

Feb. 4, Birmingham, AL SkiVision: CE at Its Peak FEB. 12-16, SNOWMASS VILLAGE, CO Evening of Education it the books—and then hit the HOST: UAB School of Optometry CE HOURS: 2 Hslopes—during SkiVision, one of LOCATION: UAB School of the most unique experiences in opto- Optometry, 1716 University Blvd. metric CE. SkiVision provides COPE- CONTACT: Amanda Kachler approved education in a relaxed, [email protected] informal setting. “You can be in a CE 205-934-5701 session in the morning and then, an www.uab.edu/optometry/ce hour later, be on the slopes with the faculty,” says Murray Fingeret, OD, a Feb. 6, Newark, DE mainstay of the educational faculty Winter Thaw Annual Conference for over 20 years. HOST: Delaware Optometric That interplay of education and Association recreation creates camaraderie KEY FACULTY: James Thimons among attendees and educators, Founded in the 1980s by optom- CE HOURS: Total: 7, max. per OD: 5 and has fostered longstanding con- etrist Robert Gold of Albany, NY, LOCATION: Embassy Suites, nections, Dr. Fingeret points out. “It’s SkiVision will once again boast the 654 S. College Ave. amazing how many people make it input and expertise of Dr. Fingeret CONTACT: Arkady Yatskevich a part of their lives, year in and year and his program cochair Leo Semes, [email protected] out,” he says. “Some doctors have OD. Other high-profi le faculty slated 302-678-3545 been with us for 20 years. We’ve for the 2016 meeting include: John http://deoa.wildapricot.org literally watched their kids grow up.” Flanagan, OD, dean at UC Berke- CD CS CT DB EL GL IN PH SD SkiVision, the longest running ley School of Optometry; Ian Ben Feb. 8, Boise, ID ‘ski-and-CE’ meeting in eye care, Gaddie, OD; Jack Schaeff er, OD; IOP Winter CE will hold its 2016 meeting Feb. 12-16 Jay Haynie, OD; and Kathy Dumb- HOST: Idaho Optometric Physicians at the Westin Snowmass Resort in leton, MSc, MCOptom, PhD. The CE CE HOURS: 4 Snowmass Village, CO. The timing of program will provide a diverse mix LOCATION: The Grove Hotel, the meeting over a three-day holiday of clinically relevant education on 245 South Capital Blvd. weekend for Presidents’ Day allows glaucoma, dry eye, external disease CONTACT: Randy Andregg attendees to bring children without and retina. [email protected]; 208-461-0001 an absence from school. SkiVision recently joined Review of Idaho.aoa.org Optometrists can earn up to 20 Optometry’s Meetings Division. CM DB GL NO NT PH RE SD TE hours of CE credits on clinically For more information or to regis- relevant topics in glaucoma, dry eye, ter, please contact Lois DiDomenico Feb. 10, Carmel, IN external disease and retina. Early at [email protected]. Indiana OA Winter Seminar morning and late afternoon educa- Additional information is available HOST: Indiana Optometric Association tion blocks allow ample time for at www.skivision.com and www. CE HOURS: 7 midday skiing. reviewofoptometry.com. LOCATION: Ritz Charles, 12156 N. Meridian St. Feb. 12-14, Kansas City, MO Feb. 12-16, Snowmass, CO CONTACT: Bridget Sims Heart of America Contact Lens Society SkiVision 2016 Annual Winter [email protected]; 317-237-3560 HOST: HOACLS Ophthalmic Conference www.ioa.org KEY FACULTY: Paul Ajamian, Michael HOST: Review of Optometry Chaglasian, Joseph Sowka, Valerie KEY FACULTY: Murray Fingeret, Leo Feb. 10-14, Timonium, MD Kattouf, Jeff ry Gerson Semes, John Flanagan, Ben Gaddie, Jack VT/Learning Related Visual Problems CE HOURS: Total: 77, max. per OD: 15 Schaeff er, Jay Haynie, Kathy Dumbleton HOST: OEP Foundation KEY FACULTY: John Abbondanza LOCATION: Sheraton Crown Center, CE HOURS: 20 CE HOURS: 35 2345 McGee St. LOCATION: Westin Snowmass Resort, LOCATION: OEP National Education CONTACT: Ron Fiegel 100 Elbert Lane Center, 2300 York Rd. [email protected] CONTACT: Lois DiDomenico CONTACT: Karen Ruder www.hoacls.org [email protected] [email protected]; 410-561-3791 AL AM BV CM CL CD CS CT DB DE EL 866-730-9257 www.oepf.org/oepf_calendar GL LT NO NT IN PE PH PM RE SV SD www.skivision.com AM BV VT TE UV VT DE EL GL RE SV

REVIEW OF OPTOMETRY DECEMBER 15, 2015 15

000_1215_ceconference_final.indd 15 12/3/15 1:36 PM Feb. 13, Lafayette, LA LOCATION: Hilton West Palm Beach, OAL Mid-Winter CE Conference 650 Okeechobee Blvd. HOST: Optometry Association of CONTACT: Palm Beach County OA Louisiana [email protected] CE HOURS: 8 www.pbcoa.org LOCATION: DoubleTree Hotel, 1521 FEB. 12-14, KANSAS CITY, MO W. Pinhook Rd. Feb. 20-27, Miami 55 Years of CE in CONTACT: Jim Sandefur AEA Cruises Eastern Caribbean [email protected]; 318-613-1392 Optometric Cruise Seminar the Heartland www.optla.org HOST: AEA Cruises idwestern optometrists have KEY FACULTY: Charles W. Ficco Mfl ocked to the Heart of America Feb. 13-20, Western Caribbean CE HOURS: 10 Contact Lens Society (HOACLS) an- Cruise (departs Fort Lauderdale) LOCATION: Aboard NCL Escape nual congress for over fi ve decades Innovations in Eye Care CONTACT: Marge McGrath to learn about the latest techniques HOST: Dr. Travel Seminars [email protected]; 888-638-6009 and products in contact lens care. KEY FACULTY: Robert Wooldridge www.optometriccruiseseminars.com The society will be hosting its 55th CE HOURS: 16 CD CT DE UV meeting in Kansas City, MO, Feb. LOCATION: departs Ft. Lauderdale 12-14. For 2016, a total of 77 CE hours CONTACT: Robert Pascal Feb. 21, Chicago [email protected]; 800-436-1028 ICO Winter CE Program will be off ered. Optometrists can www.drtravel.com HOST: Illinois College of Optometry earn a maximum of 15 CE hours dur- GL NO IN RE TE CE HOURS: 6 ing the meeting. LOCATION: Illinois College of While contact lens education re- Feb. 13-20, Playa Del Carmen, Optometry, 3241 S. Michigan Ave. mains a core part of the curriculum, Mexico CONTACT: Elizabeth Grantner medical topics are also expected Tropical CE – Riviera Maya 2016 [email protected]; 312-949-7426 to fi gure prominently. One stand- HOST: Tropical CE www.ico.edu/alumni/continuing- out presentation on deck will be a KEY FACULTY: Diana Shechtman, education panel discussion, “Advancements William Miller CL CD DE IN RE SD in Glaucoma Detection, Treatment, CE HOURS: 20 and Research,” by Paul Ajamian, OD, LOCATION: Secret’s Maroma Beach, Feb. 21, Fullerton, CA Michael Chaglasian, OD, and Joseph Carretera Federal 307 Glaucoma Pearls Sowka, OD. “This course will set the CONTACT: Stuart Autry HOST: Marshall B. Ketchum University stage for three days of premier sci- [email protected] KEY FACULTY: George Comer entifi c and practice management lec- 281-808-5763 CE HOURS: 8 tures from some of the pre-eminent www.tropicalce.com LOCATION: Marshall B. Ketchum leaders in optometric continuing AL CL DE NT PH RE UV University, 2575 Yorba Linda Blvd. education,” says HOACLS president CONTACT: Antoinette Smith William Hefner, OD, MEd. Feb. 14, Bloomington/Normal, IL [email protected]; 714-449-7495 In addition to its lineup of clinical Illinois OA Winter CE Series www.ketchum.edu/index.php/ce HOST: Illinois Optometric Assn. GL education, HOACLS will off er the KEY FACULTY: Michael Chaglasian largest exhibit hall in the Midwest, CE HOURS: 6 regular or TQ Feb. 22-23, Atlanta with vendors representing the latest LOCATION: Marriott Bloomington- AFOS/SECO 2016 (SECO’s Federal products and technologies available Normal Convention Center, Service Optometry Program) in the ophthalmic market. 201 N. Broadway Ave. HOST: Armed Forces Optometric As in previous years, HOACLS will CONTACT: Charlene Marsh Society & SECO shine a spotlight on the work of op- [email protected]; 217-525-8012 KEY FACULTY: Federal Service Chiefs tometric students and residents, with www.ioaweb.org (Army, Navy, Air Force, VA and IHS) the fourth annual scientifi c poster GL and leading optometric educators session. More than $10,000 in awards CE HOURS: 58 will be presented to the very best Feb. 14-24, Barcelona LOCATION: The Ritz Carlton & and brightest students from optom- AEA Cruises Canary Islands Georgia World Conference Center, etry schools and colleges. Optometric Cruise Seminar 181 Peachtree Street NE The Sheraton Crown Center will HOST: AEA Cruises CONTACT: Lindsay Wright provide the venue again this year for CE HOURS: 10 [email protected]; 720-442-8209 the congress; it is centrally located LOCATION: Aboard NCL Epic www.afos2020.org near activities and destinations, CONTACT: Marge McGrath CD GL NO IN PH RE RS TE UV including outdoor ice skating, Union [email protected]; 888-638-6009 Station, the World War I Museum and www.optometriccruiseseminars.com Feb. 24-28, Atlanta shopping at Crown Center. SECO 2016 Feb. 19-21, Palm Beach, FL HOST: SECO International For more information or to regis- Palm Beach Winter Seminar KEY FACULTY: John Berdahl, Donald ter, e-mail registration2@thehoalcls. HOST: Palm Beach County OA Hood, Leonard Messner, Christine org or go to www.hoacls.org. CE HOURS: 20+ Master, Whitney Hauser, Kim Reed

16 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 16 12/3/15 1:37 PM CP1215_BL SJO.indd 1 11/30/15 9:28 AM CE HOURS: Total: 175, max. per OD: 35 FEB. 24-28, ATLANTA LOCATION: Georgia World Congress Center, 285 Andrew Young International Blvd. NW CONTACT: Elizabeth Taylor DeMayo etaylor@secostaff .com; 770-451-8206 www.seco2016.com AL AM BV CM CL CD CS CT DB DE EL SECO 2016: See the Big Picture GL LT NO NT IN DS PE PH PM RE SV ant to step away from the daily SD TE UV Wgrind and get the education you need to meet new challenges Feb. 25-27, Big Sky, MT head on? Then plan to attend SECO’s MOA Winter Educational Symposium 2016 congress from Feb. 24-28 in HOST: Montana Optometric Assn. KEY FACULTY: Andrew Morgenstern, Atlanta. This year’s meeting will off er Maynard Pohl nearly 400 courses and a total of 173 CE HOURS: 13 CE credit hours, with a maximum of LOCATION: Huntley Lodge, 3720 N 35 CE credits available for ODs. Reserve St. “SECO is the best continuing edu- CONTACT: Sue Weingartner cation opportunity in optometry be- [email protected] cause it is created by the profession, 406-443-1160 for the profession,” says optometrist www.mteyes.com Stan Dickerson, president of SECO CD CT PH RE SD TE International. “Our program spans the breadth of optometric practice, Feb. 25-27, Portland, OR from the latest research to hands-on through both visual fi eld and imaging Third Party/Practice Mgmt. Seminar learning labs to practice manage- results, and will also learn methods HOST: Oregon Optometric Physicians ment challenges we all face. We are to improve detection. Association committed to delivering quality edu- • Pre- and Post-op Cataract KEY FACULTY: John McGreal, cation that will take optometrists and Surgery. During this new learning Elizabeth Cottle, Steve Farebrother, optometric staff to the next level.” lab in the exhibit hall, attendees Ronald Guerra, Shelly Sneed Adds OD education program com- can interact live with patients who CE HOURS: Total: 15, max. per OD: 13 mittee chair Paul Ajamian, “SECO is have undergone bladeless cataract LOCATION: Embassy Suites, Portland the go-to meeting for doctors who surgery, at one-day, one-week and Airport, 7900 NE 92nd Ave. one-month pre/post cataract care. CONTACT: Lynne Olson; 800-922-2045 want the tools to tackle the chal- [email protected] lenges of today’s health care environ- • Amniotic Membranes Learning www.oregonoptometry.org ment. Our unique special sessions Lab. This two-hour wet lab will give PM this year feature one of eye care’s the clinician hands-on experience in brightest young minds, John Berdahl, placing amniotic membranes. Indica- Feb. 27-28, Timonium, MD MD, who will talk about eye care ad- tions for clinical use and proper cod- Neuro-Motor Maturity, Optimizing vances on this planet and beyond.” ing and billing will also be discussed. Vision Therapy Through Testing and Here are some highlights you Presenters are Doug Devries, OD, Integration of Refl exes won’t want to miss: and David Kading, OD. HOST: OEP Foundation • “The Sky’s the Limit—Or is • Make It Your Business. This KEY FACULTY: Patti Andrich, Alex It?!” This session will question the practice management track features Andrich underlying assumptions about glau- seven courses with 11 hours of team- LOCATION: OEP National Education coma, propose new mechanisms and centered learning that SECO says will Center, 2300 York Rd. introduce new treatment options to enhance the effi ciency, productivity CONTACT: Karen Ruder help patients on earth… and perhaps and profi tability of any eye care of- [email protected]; 410-561-3791 even beyond. In this exclusive SECO fi ce. Technology in optometry takes www.oepf.org/oepf_calendar session, Dr. Berdahl will update the center stage with this new track, NO VT audience on many new innovations in which features three innovative tech- eye care, what is making news at the nology courses: (1) Patient Portals, Feb 28, Newport Beach, CA (2) EHR—Changing the Workfl ow OptoWest South, Newport Beach ASCRS meetings and special insights HOST: California Optometric Assn. into his research with NASA. Paradigm and (3) Integrating Instru- KEY FACULTY: Leo Semes, Todd • “A Fresh Look at Fields and ments into EMR. Severin, Tami Hagemeyer OCTs.” Nationally respected expert • “Beyond Ebola and HIV Up- CE HOURS: Total: 12, maximum per Don Hood, PhD, will increase your date.” You won’t want to miss this OD: 6 (and 6 staff ) understanding of glaucomatous course with infectious disease expert LOCATION: Newport Beach Marriott damage and how to measure it using Robert Kalayjian, MD. Hotel, 900 Newport Center Drive OCT and adaptive optics. You’ll see • Optometry’s Marketplace. Ex- CONTACT: Sarah Harbin the nature of glaucomatous damage tend your learning to the exhibit hall [email protected]; 916-266-5022

18 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 18 12/3/15 1:42 PM (plus earn some free CE) with SECO’s Atlanta Attractions • The Midtown Arts District houses Presentation Theater courses. • The Georgia Aquarium, home 12,000 works in the High Museum of • Social Events. The SECO Op- to 100,000 animals of 500 species. Art (www.high.org). Just across the tometric Staff Party welcomes www.georgiaaquarium.org street, Museum of Design Atlanta opticians, paraoptometrics, techs, • The World of Coca-Cola tells (www.museumofdesign.org) pres- business managers and more. The the famous soft drink’s story through ents unique urban exhibitions. Next Party is for students, residents exhibits and classic ads. www. • Piedmont Park (www. and new ODs. Celebrate SECO’s last worldofcoca-cola.com piedmontpark.org) encompasses full day with the SEE-U Saturday • Centennial Olympic Park off ers more than 180 acres of lush lawns. Party, a circus-themed evening with concerts, festivals, seasonal activities, • At the Atlanta Botanical Gar- something for everyone, including a playground and the Fountain of den (http://atlantabg.org), you can cotton candy, face painting, a lip-sync Rings. www.centennialpark.com wander through the treetops on a battle plus a performance by Georgia • The CNN Center. Guided tours 40-foot-high suspension walkway. natives Collective Soul. let visitors sit at a news anchor’s desk • Fox Theatre (https://foxtheatre. For more information or to register, and go behind the scenes. www.cnn. org) off ers live performances, includ- go to www.seco2016.com. com/tour ing concerts, Broadway and ballet.

www.coavision.org Feb 28-Mar. 4, Park City, UT Feb. 28-29, Atlanta GL LT IN DS PM RE TE Eye Ski Conference, 30th Annual COVD Applied Concepts Course HOST: Timothy Kime and James at SECO 2016 Feb. 28, Tinley Park, IL Fanelli HOST: College of Optometrists in Illinois OA Winter CE Series KEY FACULTY: Joe Pizzimenti, Alan Vision Development HOST: Illinois Optometric Association Berman, Leonard Messner, James KEY FACULTY: Carl Hillier KEY FACULTY: John McGreal Fanelli CE HOURS: 13 CE HOURS: 6 regular or TQ CE HOURS: 20 LOCATION: Omni Hotel at the CNN LOCATION: Tinley Park Convention LOCATION: The Lodge at Mountain Center, 100 CNN Center NW Center, 18451 Convention Center Drive Village, 1415 Lowell Ave. CONTACT: Penny Melkerson-Kirby CONTACT: Charlene Marsh CONTACT: Timothy Kime [email protected] [email protected]; 217-525-8012 [email protected]; 419-475-6181 330-995-0718 www.ioaweb.org www.eyeskiutah.com www.covd.org CT GL SD TE CL CD EL GL NO PM RE SV SD BV CM PM VT

THE BIG THE 2016 SECO SHOW DAILY! The SECO conference, one of the premier PICTURE educational events of the year, will take place February 24-28, 2016 — and Review of Optometry will be there! Review’s on-site editorial staff will provide live daily coverage of important show news and events, educational highlights, product FEBRUARY 24-28 | ATLANTA, GA launches and more.

Attendees on-site can pick up the SECO Daily each morning for the latest news and highlights. Those at home can stay in touch, too—a digital edition of the SECO Daily will be posted online, plus an e-newsletter will be sent out each morning with the day’s top stories.

Show copies will also be available at Review of Optometry booth #607.

000_1215_ceconference_final.indd2016_seco_HalfPage.indd 1 19 11/30/1512/3/15 11:35 12:53 AM PM INDICATIONS AND USAGE ZYLET® (loteprednol etabonate 0.5% and tobramycin 0.3% ophthalmic suspension) is a topical anti-infective and corticosteroid combination for steroid-responsive infl ammatory ocular conditions for which a corticosteroid is indicated and where superfi cial bacterial ocular infection or a risk of bacterial ocular infection exists. Please see additional Indications and Usage information on adjacent page, including list of indicated organisms.

RP0915_BL Zylet.indd 2 8/12/15 1:38 PM INDICATIONS AND USAGE (continued) Ocular steroids are indicated in infl ammatory conditions of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe such as allergic conjunctivitis, acne rosacea, superfi cial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, and where the inherent risk of steroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and infl ammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation or thermal burns, or penetration of foreign bodies. The use of a combination drug with an anti-infective component is indicated where the risk of superfi cial ocular infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye. The particular anti-infective drug in this product (tobramycin) is active against the following common bacterial eye pathogens: Staphylococci, including S. aureus and S. epidermidis (coagulase-positive and coagulase-negative), including penicillin-resistant strains. Streptococci, including some of the Group A-beta-hemolytic species, some nonhemolytic species, and some Streptococcus pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, most Proteus vulgaris strains, Haemophilus infl uenzae, and H. aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus and some Neisseria species. IMPORTANT SAFETY INFORMATION • ZYLET® is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures. • Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, defects in visual acuity and fi elds of vision. Steroids should be used with caution in the presence of glaucoma. If this product is used for 10 days or longer, intraocular pressure should be monitored. • Use of corticosteroids may result in posterior subcapsular cataract formation. • The use of steroids after cataract surgery may delay healing and increase the incidence of bleb formation. In those diseases causing thinning of the cornea or sclera, perforations have been known to occur with the use of topical steroids. The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnifi cation such as a slit lamp biomicroscopy and, where appropriate, fl uorescein staining. • Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. In acute purulent conditions, steroids may mask infection or enhance existing infections. If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated. • Employment of corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and exacerbate the severity of many viral infections of the eye (including herpes simplex). • Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use. • Most common adverse reactions reported in patients were injection and superfi cial punctate keratitis, increased intraocular pressure, burning and stinging upon instillation. Please see Brief Summary of Prescribing Information on the following page.

®/™ are trademarks of Bausch & Lomb Incorporated or its affi liates. © 2015 Bausch & Lomb Incorporated. All rights reserved. Printed in USA. US/ZYL/15/0013a

RP0915_BL Zylet.indd 3 8/12/15 1:38 PM BRIEF SUMMARY OF PRESCRIBING INFORMATION Secondary Infection: This Brief Summary does not include all the information needed to use Zylet safely The development of secondary infection has occurred after use of combinations containing and effectively. See full prescribing information for Zylet. steroids and antimicrobials. Fungal infections of the cornea are particularly prone to ® develop coincidentally with long-term applications of steroids. Zylet (loteprednol etabonate 0.5% and tobramycin 0.3% ophthalmic suspension) The possibility of fungal invasion must be considered in any persistent corneal ulceration Initial U.S. Approval: 2004 where steroid treatment has been used. DOSAGE AND ADMINISTRATION Secondary bacterial ocular infection following suppression of host responses also occurs. 2.1 Recommended Dosing USE IN SPECIFIC POPULATIONS Apply one or two drops of Zylet into the conjunctival sac of the affected eye every four to six 8.1 Pregnancy hours. During the initial 24 to 48 hours, the dosing may be increased, to every one to two hours. Teratogenic effects: Pregnancy Category C. Loteprednol etabonate has been shown to be Frequency should be decreased gradually as warranted by improvement in clinical signs. Care embryotoxic (delayed ossification) and teratogenic (increased incidence of meningocele, should be taken not to discontinue therapy prematurely. abnormal left common carotid artery, and limb fixtures) when administered orally to 2.2 Prescription Guideline rabbits during organogenesis at a dose of 3 mg/kg/day (35 times the maximum daily Not more than 20 mL should be prescribed initially and the prescription should not be clinical dose), a dose which caused no maternal toxicity. The no-observed-effect-level refilled without further evaluation [see Warnings and Precautions (5.3)]. (NOEL) for these effects was 0.5 mg/kg/day (6 times the maximum daily clinical dose). CONTRAINDICATIONS Oral treatment of rats during organogenesis resulted in teratogenicity (absent innominate artery at ≥5 mg/kg/day doses, and cleft palate and umbilical hernia at ≥50 mg/kg/day) 4.1 Nonbacterial Etiology and embryotoxicity (increased post-implantation losses at 100 mg/kg/day and decreased Zylet, as with other steroid anti-infective ophthalmic combination drugs, is contraindicated fetal body weight and skeletal ossification with ≥50 mg/kg/day). Treatment of rats at in most viral diseases of the cornea and conjunctiva including epithelial herpes simplex 0.5 mg/kg/day (6 times the maximum daily clinical dose) during organogenesis did not keratitis (dendritic keratitis), vaccinia, and varicella, and also in mycobacterial infection of result in any reproductive toxicity. Loteprednol etabonate was maternally toxic (significantly the eye and fungal diseases of ocular structures. reduced body weight gain during treatment) when administered to pregnant rats during WARNINGS AND PRECAUTIONS organogenesis at doses of ≥5 mg/kg/day. 5.1 Intraocular Pressure (IOP) Increase Oral exposure of female rats to 50 mg/kg/day of loteprednol etabonate from the start Prolonged use of corticosteroids may result in glaucoma with damage to the optic nerve, of the fetal period through the end of lactation, a maternally toxic treatment regimen defects in visual acuity and fields of vision. Steroids should be used with caution in the (significantly decreased body weight gain), gave rise to decreased growth and survival presence of glaucoma. and retarded development in the offspring during lactation; the NOEL for these effects If this product is used for 10 days or longer, intraocular pressure should be monitored. was 5 mg/kg/day. Loteprednol etabonate had no effect on the duration of gestation or 5.2 Cataracts parturition when administered orally to pregnant rats at doses up to 50 mg/kg/day during Use of corticosteroids may result in posterior subcapsular cataract formation. the fetal period. 5.3 Delayed Healing Reproductive studies have been performed in rats and rabbits with tobramycin at doses The use of steroids after cataract surgery may delay healing and increase the incidence up to 100 mg/kg/day parenterally and have revealed no evidence of impaired fertility or of bleb formation. In those diseases causing thinning of the cornea or sclera, perforations harm to the fetus. There are no adequate and well controlled studies in pregnant women. have been known to occur with the use of topical steroids. The initial prescription and Zylet should be used during pregnancy only if the potential benefit justifies the potential renewal of the medication order should be made by a physician only after examination risk to the fetus. of the patient with the aid of magnification such as a slit lamp biomicroscopy and, where 8.3 Nursing Mothers appropriate, fluorescein staining. It is not known whether topical ophthalmic administration of corticosteroids could result in 5.4 Bacterial Infections sufficient systemic absorption to produce detectable quantities in human milk. Systemic Prolonged use of corticosteroids may suppress the host response and thus increase the steroids that appear in human milk could suppress growth, interfere with endogenous hazard of secondary ocular infections. In acute purulent conditions of the eye, steroids may corticosteroid production, or cause other untoward effects. Caution should be exercised mask infection or enhance existing infection. If signs and symptoms fail to improve after when Zylet is administered to a nursing woman. 2 days, the patient should be re-evaluated. 8.4 Pediatric Use ® 5.5 Viral Infections Two trials were conducted to evaluate the safety and efficacy of Zylet (loteprednol Employment of a corticosteroid medication in the treatment of patients with a history of etabonate and tobramycin ophthalmic suspension) in pediatric subjects age zero to six herpes simplex requires great caution. Use of ocular steroids may prolong the course and years; one was in subjects with lid inflammation and the other was in subjects with may exacerbate the severity of many viral infections of the eye (including herpes simplex). blepharoconjunctivitis. 5.6 Fungal Infections In the lid inflammation trial, Zylet with warm compresses did not demonstrate efficacy Fungal infections of the cornea are particularly prone to develop coincidentally with long- compared to vehicle with warm compresses. Patients received warm compress lid term local steroid application. Fungus invasion must be considered in any persistent treatment plus Zylet or vehicle for 14 days. The majority of patients in both treatment corneal ulceration where a steroid has been used or is in use. Fungal cultures should be groups showed reduced lid inflammation. taken when appropriate. In the blepharoconjunctivitis trial, Zylet did not demonstrate efficacy compared to vehicle, 5.7 Aminoglycoside Hypersensitivity loteprednol etabonate ophthalmic suspension, or tobramycin ophthalmic solution. Sensitivity to topically applied aminoglycosides may occur in some patients. If hypersensitivity There was no difference between treatment groups in mean change from baseline develops with this product, discontinue use and institute appropriate therapy. blepharoconjunctivitis score at Day 15. There were no differences in safety assessments between the treatment groups in either trial. ADVERSE REACTIONS 8.5 Geriatric Use Adverse reactions have occurred with steroid/anti-infective combination drugs which can No overall differences in safety and effectiveness have been observed between elderly be attributed to the steroid component, the anti-infective component, or the combination. and younger patients. Zylet: NONCLINICAL TOXICOLOGY In a 42 day safety study comparing Zylet to placebo, ocular adverse reactions included injection (approximately 20%) and superficial punctate keratitis (approximately 15%). Increased 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility intraocular pressure was reported in 10% (Zylet) and 4% (placebo) of subjects. Nine percent Long-term animal studies have not been conducted to evaluate the carcinogenic potential (9%) of Zylet subjects reported burning and stinging upon instillation. of loteprednol etabonate or tobramycin. Ocular reactions reported with an incidence less than 4% include vision disorders, Loteprednol etabonate was not genotoxic in vitro in the Ames test, the mouse lymphoma discharge, itching, lacrimation disorder, photophobia, corneal deposits, ocular discomfort, TK assay, a chromosome aberration test in human lymphocytes, or in an in vivo mouse eyelid disorder, and other unspecified eye disorders. micronucleus assay. The incidence of non-ocular reactions reported in approximately 14% of subjects was Oral treatment of male and female rats at 50 mg/kg/day and 25 mg/kg/day of loteprednol headache; all other non-ocular reactions had an incidence of less than 5%. etabonate, respectively, (500 and 250 times the maximum clinical dose, respectively) prior to and during mating did not impair fertility in either gender. No impairment of fertility was Loteprednol etabonate ophthalmic suspension 0.2% - 0.5%: noted in studies of subcutaneous tobramycin in rats at 100 mg/kg/day (1700 times the Reactions associated with ophthalmic steroids include elevated intraocular pressure, maximum daily clinical dose). which may be associated with infrequent optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, delayed wound healing and secondary PATIENT COUNSELING INFORMATION ocular infection from pathogens including herpes simplex, and perforation of the globe This product is sterile when packaged. Patients should be advised not to allow the dropper where there is thinning of the cornea or sclera. tip to touch any surface, as this may contaminate the suspension. If pain develops, redness, itching or inflammation becomes aggravated, the patient should be advised to In a summation of controlled, randomized studies of individuals treated for 28 days or consult a physician. As with all ophthalmic preparations containing benzalkonium chloride, longer with loteprednol etabonate, the incidence of significant elevation of intraocular patients should be advised not to wear soft contact lenses when using Zylet. pressure (≥10 mm Hg) was 2% (15/901) among patients receiving loteprednol etabonate, 7% (11/164) among patients receiving 1% prednisolone acetate and 0.5% (3/583) among MANUFACTURER INFORMATION patients receiving placebo. BAUSCH & LOMB INCORPORATED Tobramycin ophthalmic solution 0.3%: TAMPA, FLORIDA 33637 USA The most frequent adverse reactions to topical tobramycin are hypersensitivity and ©Bausch & Lomb Incorporated localized ocular toxicity, including lid itching and swelling and conjunctival erythema. Zylet is a registered trademark of Bausch & Lomb Incorporated. These reactions occur in less than 4% of patients. Similar reactions may occur with the topical use of other aminoglycoside antibiotics. Based on 9007705-9004405 Revised 08/2013 US/ZYL/15/0014

RRP0915_BLP0915_BL ZZyletylet PPI.inddI.indd 1 88/12/15/12/15 1:401:40 PMPM March

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

12345 Eye Ski Conference (begins Feb. 28) AZ-AAO Annual Spring Meeting 2016 OEP Foundation VT/Vision Dysfunctions Tropical CE – Tahiti 2016 Borish Symposium

6 7 8 9 10 11 12 Tropical CE – Tahiti 2016 VT/Vision Dysfunctions ICO Resident Grand OEP Strabismus and Rounds Amblyopia Borish Symposium Ocular Disease: Part I

13 14 15 16 17 18 19 NCC/BCLA Research Symposium PSS Symposium on Ocular Disease OEP Strabismus and OEP VT/Strabismus and Amblyopia Amblyopia UAB Primary Eye Care Update Ocular Disease: Part II OSU Binocular Vision ICO Winter/Spring and Pediatrics Forum CE Program

20 21 22 23 24 25 26 PSS Symposium on Ocular Disease OEP VT/Strabismus NC Eastern District and Amblyopia Clinical Grand Rounds UAB Primary Eye Care Update NECO Cornea Symposium

27 28 29 30 31 OEP Foundation Art + Science of Optometric Care (ends Apr. 4)

Mar. 3-7, Burlington, Ontario, Canada Mar. 4-12, Mo’orea and Bora Bora, HOST: Tropical CE VT/Visual Dysfunctions French Polynesia KEY FACULTY: Paul Ajamian, Maynard HOST: OEP Foundation Tropical CE – Tahiti 2016 Pohl KEY FACULTY: Steen Aalberg CE HOURS: 35 EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders LOCATION: 2080 Appleby Line Ste. AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery E6 AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision CONTACT: Karen Ruder BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease [email protected] CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology 410-561-3791 CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis www.oepf.org/oepf_calendar CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy AM BV VT

REVIEW OF OPTOMETRY DECEMBER 15, 2015 23

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 2323 112/3/152/3/15 12:5412:54 PMPM LOCATION: Illinois College of Optometry, 3241 S. Michigan Ave. CONTACT: Elizabeth Grantner [email protected] 312-949-7426 www.ico.edu/alumni/continuing- MARCH 13-14, NETHERLANDS education Go Dutch! Charge Up Your CE in the Netherlands AL AM BV CM CL CD CS CT DE EL GL LT NO NT IN PH RE SV SD TE UV ptometric CE is Ono longer just a Mar. 12-13, Fullerton, CA domestic venture. The Ocular Disease: Part I Netherlands Contact HOST: Marshall B. Ketchum University Lens Congress (NCC) KEY FACULTY: George Comer, David and the British Con- Sendrowski, Judy Tong tact Lens Association CE HOURS: 17 (BCLA) will cohost a LOCATION: Marshall B. Ketchum research symposium themed “Get Cheryl Donnelly, CEO of BCLA, University, 2575 Yorba Linda Blvd. in Charge,” as part of NCC 2016 in says, “With the BCLA conference CONTACT: Antoinette Smith Veldhoven, the Netherlands, from becoming a biennial event, the NCC [email protected] March 13-14. 2016 will provide an opportunity for 714-449-7495 The symposium is designed researchers to publish the results of www.ketchum.edu/index.php/ce to maintain the high reputation new studies, providing continuity in a AL AM CL CD CS CT DB DE EL GL NO developed by the BCLA for show- non-conference year. As the world of IN PH SD UV casing world-class, clinically rel- contact lenses continues to evolve, Mar. 12-13, Kansas City, KS evant research, and nurturing new the publication of new research al- A New Old-fashioned Approach to researchers and young academics. lows practitioners to keep abreast of Strabismus and Amblyopia All abstracts will continue to be pub- the latest thinking in this area.” HOST: Jane Philbrook lished in Contact Lens and Anterior The NCC was founded in 2006 KEY FACULTY: Rob Lewis Eye (CLAE). and has grown to become the larg- CE HOURS: TBD “The NCC has grown to be- est contact lens conference on the CONTACT: Karen Ruder come a respected congress within mainland of Europe. The NCC at- [email protected] the contact lens community, and tracts more than 1,500 contact lens 410-561-3791 provides an ideal opportunity to practitioners and optometrists dur- www.oepf.org/oepf_calendar hear about new research,” says ing each meeting. Although the vast AM BV VT James Wolff sohn, professor at Aston majority of the attendees are from University and BCLA academic Dutch-speaking countries, NCC is Mar. 13, Chicago chair. “Our younger researchers are internationally well represented, and ICO Winter/Spring CE Program carrying out interesting studies in 90% of the lectures are presented HOST: Illinois College of Optometry this fi eld, and the BCLA-sponsored in English by leading experts from CE HOURS: 6 symposium will allow them the op- around the world. LOCATION: Illinois College of portunity to share their fi ndings with For information and registration, Optometry, 3241 S. Michigan Ave. the wider community.” go to bcla.org.uk or ncc2016.com. CONTACT: Elizabeth Grantner [email protected] 312-949-7426 CE HOURS: 20 19555 N. 59th Ave. www.ico.edu/alumni/continuing- LOCATION: Sofi tel Mo’orea Resort and CONTACT: Carla Engelke education InterContinental Bora Bora Resort and [email protected] AL NO NT Spa, BP 28 www.aaopt.org/azchapter CONTACT: Stuart Autry Mar. 13-14, Veldhoven, Netherlands [email protected] Mar. 5-6, Bloomington, IN NCC/BCLA Research Symposium 281-808-5763 Borish Symposium HOST: Netherlands Contact Lens www.tropicalce.com HOST: IU School of Optometry Congress and the British Contact Lens CM CT GL NO PH RE CE HOURS: 16 Association CONTACT: Cheryl Oldfi eld LOCATION: Veldhoven, the Mar. 5, Glendale, AZ coldfi [email protected] Netherlands AZ-AAO Chapter Annual Spring 812-856-3502 www.ncc2016.com Meeting 2016 www.opt.indiana.edu/ce/seminars.htm CL HOST: American Academy of Optometry Arizona Chapter Mar. 11, Chicago Mar. 17-20, Timonium, MD CE HOURS: 6 ICO Resident Grand Rounds VT/Strabismus and Amblyopia LOCATION: Midwestern University HOST: Illinois College of Optometry HOST: OEP Foundation Arizona College of Optometry, CE HOURS: 4 KEY FACULTY: Robert A. Hohendorf

24 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 24 12/3/15 12:54 PM CE HOURS: 28 CE HOURS: 7 617-587-5687 LOCATION: OEP National Education LOCATION: Ohio State University www.neco.edu/academics/ Center, 2300 York Rd. College of Optometry, continuing-education CONTACT: Karen Ruder 338 W. 10th Ave. CD CS DE [email protected] CONTACT: Catherine McDaniel 410-561-3791 [email protected] Mar. 22, Raleigh, NC www.oepf.org/oepf_calendar 614-688-1425 Clinical Grand Rounds AM BV VT http://optometry.osu.edu/ce/ HOST: North Carolina Eastern District bvpforum.cfm Optometric Society Mar. 17-22, Tyson’s Corner, VA AM BV NO PE PH KEY FACULTY: Ron Melton, Randall Symposium on Ocular Disease Thomas HOST: PSS EyeCare Mar. 18-20, Birmingham, AL CE HOURS: 2 KEY FACULTY: Ron Melton, Randall Primary Eye Care Update LOCATION: Raleigh Marriott Crabtree Thomas, Mile Brujic, William Jones, HOST: UAB School of Optometry Valley, 4500 Marriott Drive Elliot Kirstein, Deepak Gupta CE HOURS: 18 CONTACT: Michael Haines CE HOURS: 18 LOCATION: UAB School of 919-934-2020 LOCATION: Crowne Plaza Hotel, Optometry, 1716 University Blvd. www.nceyes.org 1960 Chain Bridge Rd. CONTACT: Amanda Kachler AL CD DE EL GL IN PH UV CONTACT: Sonia Kumari [email protected] [email protected] 205-934-5701 Mar. 31-Apr. 4, Grand Rapids, MI 203-415-3087 www.uab.edu/optometry/ce Art + Science of Optometric Care www.psseyecare.com HOST: OEP Foundation AL AM CM CL CD CS DB DE EL GL LT Mar. 20, Boston KEY FACULTY: Robert A. Hohendorf NO NT IN PH PM RE RS SD Cornea Symposium CE HOURS: 35 HOST: New England College of LOCATION: South Kent Vision Center, Mar. 18, Columbus, Ohio Optometry 3977 Maple St. SW Binocular Vision and Pediatrics CE HOURS: 7 CONTACT: Karen Ruder Forum LOCATION: The Colonnade Hotel, [email protected] HOST: Ohio State University College 120 Huntington Ave. 410-561-3791 of Optometry CONTACT: Tony Cavallerano www.oepf.org/oepf_calendar KEY FACULTY: Suzanne Wickum [email protected] AM BV VT

Up to 28 CE SAVE THE DATE! Credits San Diego (COPE approval pending) Joint Meeting April 7 - 10, 2016

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IN VISION CARE offers combined 28 CE credits. 2016 OPTOMETRIC CORNEA, CATARACT Additional CE fees if attending both meetings. See website for details: AND REFRACTIVE SOCIETY www.reviewofoptometry.com/Conferences REVIEW OF OPTOMETRY® EDUCATIONAL MEETINGS OF CLINICAL EXCELLENCE Hotel del Coronado A Legendary Beachside Getaway 1500 Orange Avenue | Coronado, California 92118 Phone: 619-435-6611 Paul M. Karpecki,OD, FAAO Andrew S. Morgensatern, OD, FAAO Review Program Chair Discounted room rate $279/NIGHT President, OCCRS www.reviewofoptometry.com/SanDiego2016 Or E-mail Lois DiDomenico: [email protected] or Call: 866-658-1772

Administered by

Review of Optometry® *Approval pending

FINAL LAYOUT DEC 8.indd 25 12/8/15 2:01 PM April

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

12 OEP Foundation Art + Science of Optometric Care (begins Mar. 31) ICO Resident Grand Miami Nice Rounds Educational Symposium

3456789 OEP Fdn. Art + Science of Optometric Care New Technologies and Treatments in VIsion Care – San Diego Joint meeting with OCCRS Annual Symposium Miami Nice Educational Optometric CE Symposium Annual Symposium NECO Retina RSO Spring Seminar Dilemmas: What Now?

10 11 12 13 14 15 16 NT&T San Diego COVD Annual Meeting and OCCRS Joint Meeting AAO New Jersey Chapter CE Optometric CE AEA Cruises Mediterranean Optometric Cruise Seminar Annual Symposium WOA 2016 Spring Seminar 2016 Coeur d’Alene CE Cornea & Contact Vision Expo East Lens CE RSO Spring Seminar NMOA Annual Convention Indiana OA Annual Convention Nutrition and the Eye Symposium

17 18 19 20 21 22 23 AEA Cruises Mediterranean Optometric Cruise Seminar Vision Expo East Mountain West Council of Optometrists Annual Congress NMOA Annual PSS Conference on Comprehensive EyeCare Convention UAB Evening of 2016 Kentucky OA Indiana OA Annual Education Spring Congress Convention CE Seminar and OptoWest North Optifair Canada – Walnut Creek Nutrition and the Eye Symposium

24 25 26 27 28 29 30 PSS Conference on Comprehensive EyeCare Oklahoma Association of Optometric Physicians Vision Summit 2016 Kentucky OA Spring Congress 2016 Kansas Optometric Assn. Annual Convention and Seminar CE Seminar and 2016 Arkansas Optometric Association Spring Convention (ends May 1) Optifair Canada MOA Great Lakes Eyecare Conference CE in the Southwest (ends May 1) Florida Chapter – AAO CE UC Berkeley Morgan Symposium (ends May 1) ICO Resident Grand Rounds

26 REVIEW OF OPTOMETRY DECEMBER 15, 2015

FFINALINAL LLAYOUTAYOUT DDECEC 88.indd.indd 2266 112/8/152/8/15 2:012:01 PMPM Apr. 1, Chicago ICO Resident Grand Rounds HOST: Illinois College of Optometry CE HOURS: 4 LOCATION: Illinois College of Optometry, 3241 S. Michigan Ave. CONTACT: Elizabeth Grantner [email protected] 312-949-7426 Soak Up the CE and the Sun at OCCRS APRIL 7-10, SAN DIEGO www.ico.edu/alumni/continuing- education he 2016 educational AL AM BV CM CL CD CS CT DE EL GL Tsymposium of the LT NO NT IN PH RE SV SD TE UV Optometric Cornea, Cataract and Refractive Apr. 2-3, Coral Gables, FL Society (OCCRS) is the Miami Nice Educational Symposium meeting to attend for the HOST: Miami Dade Optometric latest continuing education Physicians Association regarding cornea, cataract KEY FACULTY: Anthony Litwak, Brian and refractive technology, DenBeste, Kim Reed, Albert Woods, OCCRS promises. Tim Underhill This year’s meeting will refractive surgery, ocular disease and CE HOURS: 17 be held in conjunction with the fi rst much more. Eight to 12 hours of CE LOCATION: Coral Gables Country New Technologies and Treatments in Club, 997 North Greenway Dr. Vision Care meeting of the year. Dur- credit will be available. CONTACT: Stephen Morris ing the event, OCCRS will host key The 2016 meeting will be held at [email protected] opinion leaders, experts and world- the world-famous Hotel Del Corona- miamieyes.org class speakers providing the most do on Coronado Island across from CM CD DB GL NO NT IN PH RE SD up-to-date, COPE-approved educa- San Diego. tion on the optometric care of ocular OCCRS, formerly known as the Apr. 3, Boston surgery, anterior segment disease and Optometric Council on Refractive Retinal Dilemmas: What Now? refractive correction, OCCRS says. Technology, was founded in 2002. HOST: New England Col. of Optometry Come hear the latest research on For more information or to reg- KEY FACULTY: Steven Ferrucci, advanced treatments for keratoco- ister, contact Andrew Morgenstern, Baharak Asefzadeh nus, femto laser-assisted cataract [email protected] or CE HOURS: 5 surgery, corneal and lens-based go to www.occrs.org. LOCATION: New England College of Optometry, 424 Beacon St. www.reviewofoptometry.com/ Apr. 9-10, Las Vegas CONTACT: Tony Cavallerano sandiego2016 Optometric CE Annual Symposium [email protected] CM DE EL GL IN PH RS HOST: Optometric CE 617-587-5687 KEY FACULTY: William Jones, Bryan www.neco.edu/academics/ Apr. 7-10, San Diego (Coronado Island) Wolynski, Michael Santarlas, Michael continuing-education OCCRS Annual Education Symposium Samuel RE – Joint Meeting with NT&T San Diego CE HOURS: 12 HOST: Optometric Cornea, Cataract LOCATION: Marriott Las Vegas, 325 Apr. 7-10, San Diego (Coronado Island) and Refractive Society Convention Center Drive New Technologies and Treatments in KEY FACULTY: Paul Karpecki, Andy CONTACT: Joel Rothschild Vision Care – San Diego/OCCRS Morgenstern, Marc Bloomenstein, [email protected] HOST: Review of Optometry David Geff en, Jim Owen, Bill Tullo 909-255-0464 KEY FACULTY: Paul Karpecki CE HOURS: 8-12 www.optometricce.org CE HOURS: 16, plus 8-12 for OCCRS LOCATION: Hotel Del Coronado, AL CL CD DB DE EL GL LT NO NT IN joint meeting 1500 Orange Ave. PH RE SD TE LOCATION: Hotel del Coronado, CONTACT: Andrew Morgenstern 1500 Orange Ave. [email protected] Apr. 9-10, San Antonio, TX CONTACT: Lois DiDomenico 202-423-3500 RSO Spring Seminar [email protected] www.occrs.org HOST: Rosenberg School of 866-658-1772 CM CL CD CS CT DE EL LT PH RS TE Optometry CE HOURS: 16 EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders LOCATION Rosenberg School of AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Optometry, 9725 Datapoint AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision CONTACT: Sandra Fortenberry BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease [email protected] CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology 210-283-6856 CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis www.uiw.edu/optometry/continuing- CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy education

REVIEW OF OPTOMETRY DECEMBER 15, 2015 27

FINAL LAYOUT DEC 8.indd 27 12/8/15 2:02 PM APRIL 14-17, NEW YORK CITY

Get in a New York State of Mind at Vision Expo East f you mostly think of optical dis- Ipensing and fancy frames when you hear the name Vision Expo, think again. International Vision Expo East has cemented itself as one of the major players in optometric continu- ing education in recent years, and the lineup for 2016 is no exception. The meeting, to be held April 14- 17 at the Javits Center in New York City, will bring back favorites like the Global Contact Lens Forum and the Ocular Surface Disease and Wellness Forum, but also adds new programs for 2016, including Lightning Rounds of continuing education credit will successful business. This course—new for fast-based education and a “Les- be available in this course, featur- for 2016—will have representatives sons from Facebook” symposium. ing a new learning format and the from Facebook on hand to share tips Vision Expo East will off er 320 hours opportunity to hear from multiple on how to use this social media tool of CE credit, and optometrists can speakers in a speed-dating–type to engage customers and market earn up to 10 hours per day of the setting. Speakers will rotate between your business. meeting, or up to 40 hours total. two rooms and give a short review • The Ritz-Carlton Leadership “Vision Expo education off ers of the topics—covering glaucoma Center. This keynote series, off ering exclusive insights into the clinical and and anterior segment disease—off er- three hours of CE credit, will teach business trends and best practices ing attendees the benefi t of multiple you the benchmark, award-winning that today’s eye care professionals expert perspectives within one class. business practices used by the Ritz- need to know to be successful,” says Presenters will include optometrists Carlton to take back to your practice Vision Expo conference advisory Eric Schmidt, Kirk Smick, Charlie and incorporate into patient care, board co-chair Ian Ben Gaddie, OD. Ficco, Louise Sclafani and Douglas focusing on the Ritz-Carlton method- “With strong emphasis on the vision- Devries. ology for customer service, employee ary ideas and leaders in our industry, engagement and leadership develop- 2016 will support attendees’ eff orts ment. to stay abreast of important changes For more information or to register, and advances that impact how we, as contact Leigh Mann, lmann@ a community, address issues of pa- reedexpo.com, or go to www. tient care as well as practice manage- visionexpoeast.com. ment and business growth.” Here’s a snapshot of a few meeting “Live From New York, it’s...” highlights you won’t want to miss: It’s fun and free to attend the tapings • Ocular Surface Disease and of popular television shows shot in Wellness Symposium. This event will New York City. The wait for advance off er three hours of CE credit and • Vision Series. This course will tickets is often long, so it’s best to insight into why your practice should off er a mix of clinical and medical- write in for them or reserve online mirror a preventative care model. In oriented topics, presented in a social well in advance of your desired date. addition, you will learn how to follow environment. Sessions will be held Still, many shows have standby op- this approach to diagnose and treat during breakfast, lunch and a cocktail tions if you’re willing to wait in line. your patients, better recognize dry hour at the end of the day. Check While you’re at Vision Expo East, eye diseases and expand the quality back with Vision Expo as topics for here are some shows that off er tick- and consistency of care you are pro- this course are announced. ets (source: www.nycgo.com). viding by following easy-to-use dry • Marketing Lessons from Face- • The Dr. Oz Show, 320 W. 66th eye disease recommendations. book. A strong social media pres- St. Tickets are available online (www. • Lightning Rounds. Four hours ence is essential these days for any doctoroz.com/tickets). For standby

28 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 28 12/3/15 1:44 PM Apr. 10, Fullerton, CA tickets, an audience staff er will be the 11:30pm live taping, though you’re Cornea & Contact Lens CE Program at ABC Studios, 320 W. 66th St., at not guaranteed admission. HOST: Marshall B. Ketchum University 8:40am and 1:40pm on most Tues- • Today (NBC), 30 Rockefeller KEY FACULTY: Timothy Edrington days, Wednesdays and Fridays. Plaza. No tickets are necessary. To CE HOURS: 8 • Good Morning America RSVP and for more info, visit today. LOCATION: Marshall B. Ketchum (ABC), Times Square (at Broad- com. University, 2575 Yorba Linda Blvd. way and West 44th St.). To re- • The Tonight Show Starring CONTACT: Antoinette Smith ceive tickets, submit your request Jimmy Fallon (NBC), Studio 6B, [email protected]; 714-449-7495 www.ketchum.edu/index.php/ce online (abcnews.go.com/GMA/ 30 Rockefeller Plaza. To book free CL IN mailform?id=12943471). tickets, visit showclix.com. The ticket • Late Night with Seth Meyers release date is posted on the show’s Apr. 12-16, St. Louis, MO (NBC), Studio 8G, 30 Rockefeller Twitter page (@fallontonight). COVD 46th Annual Meeting Plaza. For free tickets to future Standby tickets are distributed at HOST: College of Optometrists in shows, call 212-664-3056 (ticket 9am under the NBC marquee on the Vision Development lines are open Monday–Friday, 9am 49th St. side of 30 Rock. KEY FACULTY: Dominick Maino, to 5pm, ET). Tickets are generally • The View (ABC), 320 W. 66th Sherry Bass, Susan Cotter, Kia Eldred, booked four to six weeks in advance. St. Apply for tickets online at 1iota. Philip Bugaiski, Derek Tong Separate tickets to see Meyers re- com. For standby tickets, pick up a CE HOURS: Total: 86, Maximum per hearse his monologue are available number from an audience associate OD: 32 on show dates at the NBC Experi- between 8am and 9am at the audi- LOCATION: Hyatt Regency St. Louis ence Store (30 Rockefeller Plaza), ence entrance. at the Arch, 315 Chestnut St. facing 49th St., at 12:30pm. CONTACT: Penny Melkerson-Kirby • Live! with Kelly & Michael, 7 NYC: A Culinary Mecca [email protected]; 330-995-0718 Lincoln Square, southeast corner of www.covd.org If you haven’t eaten one of the best Columbus Avenue and West 67th AM BV CM NO NT PE PM SV VT meals of your life in New York City, St. The wait may be up to a year for you haven’t looked hard enough, as advance tickets, but it is still pos- Apr. 13-14, Green Bay, WI the Big Apple is home to some of the sible to get same-day tickets. To 2016 Spring Seminar fi nest restaurants in the world. Try obtain tickets in advance, fi ll out the HOST: Wisconsin Optometric one of these Yelp suggestions: ticket-request online form (http:// Association • Upstate CE HOURS: 14 livekellyandmichael.dadt.com/live- 95 1st Ave. LOCATION: Hyatt on Main, ticket-requests). To get same-day www.upstatenyc.com 333 Main St. tickets, arrive at the southeast corner • Traif CONTACT: Joleen Breunig of Columbus Avenue and West 67th 229 S. 4th St. [email protected] St. as early as 7am for a standby 608-824-2200 number. www.traifny.com • Battersby www.woa-eyes.org • The Meredith Vieira Show, 30 GL RE SD Rockefeller Plaza (between Fifth 255 Smith St. www.battersbybrooklyn.com and Sixth avenues and W. 49th and April 13-16, Myrtle Beach, SC W. 50th streets). You can request • Chef’s Table at Brooklyn Fair American Academy of Optometry tickets through the show’s online 200 Schermerhorn St. New Jersey Chapter form (http://meredithvieirashow. www.brooklynfare.com/chefs-table HOST: Dennis Lyons com/tickets). Standby tickets are re- • The River Café KEY FACULTY: Joseph Sowka, Mile leased at 8am for the morning taping 1 Water St. Brujic and noon for the afternoon one. www.rivercafe.com CE HOURS: 16 • The Rachael Ray Show, Chelsea • Amelie LOCATION: Embassy Suites at Television Studios, 221 W. 26th St. To 22 W. 8th St. Kingston Plantation, request tickets, visit rachaelrayshow. www.ameliewinebar.com 9800 Queensway Blvd. CONTACT: Dennis Lyons com. • Da Claudio [email protected]; 732-920-0110 • Saturday Night Live (NBC), 30 21 Ann St. CD DB EL GL IN RE SD UV Rockefeller Plaza. Tickets are given www.daclaudionyc.com out once a year through a lottery. • Luke’s Lobster Apr. 13-23, Barcelona to Athens 26 S. William St. To enter for 2017, send an email to AEA Cruises Mediterranean www.lukeslobster.com [email protected] during the Optometric Cruise Seminar month of August only. Standby tick- • Bea Restaurant & Bar HOST: AEA Cruises ets (one per person) are distributed 403 W. 43rd St. CE HOURS: 10 at 7am on the West 49th St. side of www.beanyc.com LOCATION: Silversea Silverwind 30 Rockefeller Plaza on the morn- • ABC Kitchen CONTACT: Marge McGrath ings of the tapings. You can choose 35 E. 18th St. [email protected] between the 8pm dress rehearsal and www.abckitchennyc.com 888-638-6009 www.optometriccruiseseminars.com

REVIEW OF OPTOMETRY DECEMBER 15, 2015 29

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Apr. 15-17, Albuquerque, NM New Mexico Optometric Association Annual Convention APRIL 21-23, HOST: New Mexico Optometric MWCO: 24 Hours of CE in Las Vegas LAS VEGAS Association ant to meet KEY FACULTY: Steve Ferruci, Jeff Wyour annual Walline, Greg Schultz, Doug Devries, continuing educa- Kim Reed, John Pitcher III tion requirements at CE HOURS: 22 just one meeting? LOCATION: Isleta Pueblo Resort, The Mountain West 1100 Broadway SE Council of Optom- CONTACT: Richard Montoya etrists (MWCO) has [email protected] lined up an all-star 575-751-7242 meeting that will www.newmexicooptometry.org allow many optom- DB GL IN PH RE SD etrists the opportu- nity to do just that. Apr. 15-17, Indianapolis The MWCO 2016 Indiana Optometry’s Meeting – the annual meeting will off er a total of and practice management,” Dr. 119th Annual Convention 72 hours of CE credit and a maxi- Wooldridge says. “Always a crowd HOST: Indiana Optometric mum of 24 hours for ODs at its 2016 favorite, Dr. John McGreal will review Association congress, which will be held April the latest trends in contemporary CE HOURS: 16 21-23 in Las Vegas. medicine, and coding and billing LOCATION: Westin Hotel Downtown “This year’s educational program requirements.” Indianapolis, 50 South Capital Ave. is second to none for meetings of Summing up, Dr. Wooldridge CONTACT: Bridget Sims this size,” says optometrist Robert notes that this year’s congress off ers [email protected] Wooldridge, MWCO’s president and “a broad-based educational program 317-237-3560 education coordinator. “We have to better enable our attendees to www.ioa.org several of the top speakers in the provide exceptional care for their nation covering a wide variety of patients for many years to come.” Apr. 16-17, St. Louis topics, including updates on diabetic The congress will be held at the Nutrition and the Eye Symposium IX retinopathy and other retinal dis- Aria Resort, which features a vaca- HOST: University of Missouri-St. Louis eases presented by Drs. Jay Haynie, tion-like atmosphere, combined with College of Optometry and Ocular Leo Semes and retinal specialist the meeting’s casual and friendly ap- Nutrition Society Michael Stewart, MD.” You can also proach, allowing doctors the chance KEY FACULTY: Aron Barbey, Liz expect several courses on contact to relax and enjoy themselves while Johnson, Lisa Renzi Hammond lenses and corneal concerns to be learning the latest updates in patient CE HOURS: 12 presented by Dr. Jeff Sonsino. In care, MWCO says. LOCATION: TBD CONTACT: Lis Ellerbusch addition, “Dr. Scot Morris will both For more information or to regis- [email protected] educate and entertain us with his ter, contact Tracy Abel: tracyabel@ 314-516-5615 courses on anterior segment disease earthlink.net, 888-376-6926. NT

Apr. 14-17, New York Apr. 15-16, Coeur d’Alene, Idaho Apr. 17, Walnut Creek, CA Vision Expo East 2016 Coeur d’Alene CE OptoWest North – Walnut Creek HOST: International Vision Expo & HOST: Pacifi c University College of HOST: California Optometric Conference Optometry Association CE HOURS: Total: 320, maximum per KEY FACULTY: Mark Andre, Fraser KEY FACULTY: Leo Semes, Todd OD: 40 Horn, Spokane VA optometry Severin, Tami Hagemeyer LOCATION: Jacob Javits Center, residents CE HOURS: Total: 12, maximum per 655 W. 34th St. CE HOURS: 10 OD: 6 (and 6 staff ) CONTACT: Leigh Mann LOCATION: Coeur d’Alene Resort and LOCATION: Walnut Creek Marriott, [email protected] Spa, 115 S. 2nd St. 2355 N. Main St. 203-840-5452 CONTACT: Jeanne Oliver CONTACT: Sarah Harbin www.visionexpoeast.com jeanne@pacifi cu.edu [email protected] AL AM BV CM CL CD CS CT DB DE EL 503-352-2740 916-266-5022 GL LT NO NT IN DS PE PH PM RE RS www.pacifi cu.edu/future-graduate- www.coavision.org SV SD TE UV VT professional/colleges/college- GL LT IN DS PM RE TE

30 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 30 12/3/15 1:47 PM When treating your patients with bacterial conjunctivitis – Unleash power against pathogens of concern. • The first and only topical ophthalmic chlorofluoroquinolone1 • Provides long-lasting tear concentrations2 • Proven efficacy against a broad spectrum of pathogens including1,3: – S. aureus, S. epidermidis, S. pneumoniae, and H. influenzae – Pseudomonas aeruginosa

Indication BESIVANCE® (besifl oxacin ophthalmic suspension) 0.6% is a quinolone antimicrobial indicated for the treatment of bacterial conjunctivitis caused by susceptible isolates of the following bacteria: Aerococcus viridans*, CDC coryneform group G, Corynebacterium pseudodiphtheriticum*, Corynebacterium striatum*, Haemophilus infl uenzae, Moraxella catarrhalis*, Moraxella lacunata*, Pseudomonas aeruginosa*, Staphylococcus aureus, Staphylococcus epidermidis, Staphylococcus hominis*, Staphylococcus lugdunensis*, Staphylococcus warneri*, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, Streptococcus salivarius* *Effi cacy for this organism was studied in fewer than 10 infections. Important Safety Information about BESIVANCE® • BESIVANCE® is for topical ophthalmic use only, and should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye. • As with other anti-infectives, prolonged use of BESIVANCE® may result in overgrowth of non-susceptible organisms, including fungi. If super-infection occurs, discontinue use and institute alternative therapy. • Patients should not wear contact lenses if they have signs or symptoms of bacterial conjunctivitis or during the course of therapy with BESIVANCE®. • The most common adverse event reported in 2% of patients treated with BESIVANCE® was conjunctival redness. Other adverse events reported in patients receiving BESIVANCE® occurring in approximately 1-2% of patients included: blurred vision, eye pain, eye irritation, eye pruritus and headache. • BESIVANCE® is not intended to be administered systemically. Quinolones administered systemically have been associated with hypersensitivity reactions, even following a single dose. Patients should be advised to discontinue use immediately and contact their physician at the fi rst sign of a rash or allergic reaction. • Safety and effectiveness in infants below one year of age have not been established. Please see brief summary of Prescribing Information on adjacent page. To learn more about BESIVANCE® call your Bausch + Lomb sales representative today. References: 1. BESIVANCE® Prescribing Information, September 2012. 2. At 12 hours, the concentration of besifl oxacin in tears was >10 μg/mL. Proksch JW, Granvil CP, Siou-Mermet R, Comstock TL, Paterno MR, Ward KW. Ocular pharmacokinetics of besifl oxacin following topical administration to rabbits, monkeys, and humans. J Ocul Pharm Ther. 2009;25(4):335-344. 3. Comstock TL, Paterno MR, Usner DW, Pichichero ME. Effi cacy and safety of besifl oxacin ophthalmic suspension 0.6% in children and adolescents with bacterial conjunctivitis: a post hoc, subgroup analysis of three randomized, double-masked, parallel-group, multicenter clinical trials. Paediatr Drugs. 2010;12(2):105-112.

Besivance is a trademark of Bausch & Lomb Incorporated or its affi liates. © 2015 Bausch & Lomb Incorporated. All rights reserved. US/BES/15/0010

RO1215_BL Besivance.indd 1 11/18/15 2:53 PM BRIEF SUMMARY OF PRESCRIBING INFORMATION times a day (16 doses total). Following the first and last dose, the maximum plasma be- This Brief Summary does not include all the information needed to use Besivance sifloxacin concentration in each patient was less than 1.3 ng/mL. The mean besifloxacin

safely and effectively. See full prescribing information for Besivance. Cmax was 0.37 ng/mL on day 1 and 0.43 ng/mL on day 6. The average elimination half-life of besifloxacin in plasma following multiple dosing was estimated to be 7 hours. Besivance (besifloxacin ophthalmic suspension) 0.6% 12. Microbiology Sterile topical ophthalmic drops Besifloxacin is an 8-chloro fluoroquinolone with a N-1 cyclopropyl group. The compound Initial U.S. Approval: 2009 has activity against Gram-positive and Gram-negative bacteria due to the inhibition of 1 INDICATIONS AND USAGE both bacterial DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme Besivance® (besifloxacin ophthalmic suspension) 0.6%, is indicated for the treatment of required for replication, transcription and repair of bacterial DNA. Topoisomerase IV is an bacterial conjunctivitis caused by susceptible isolates of the following bacteria: essential enzyme required for partitioning of the chromosomal DNA during bacterial cell division. Besifloxacin is bactericidal with minimum bactericidal concentrations (MBCs) Aerococcus viridans*, CDC coryneform group G, Corynebacterium pseudodiphtheriticum*, generally within one dilution of the minimum inhibitory concentrations (MICs). Corynebacterium striatum*, Haemophilus influenzae, Moraxella catarrhalis*, Moraxella The mechanism of action of fluoroquinolones, including besifloxacin, is different from that lacunata*, Pseudomonas aeruginosa*, Staphylococcus aureus, Staphylococcus β epidermidis, Staphylococcus hominis*, Staphylococcus lugdunensis*, Staphylococcus of aminoglycoside, macrolide, and -lactam antibiotics. Therefore, besifloxacin may be warneri*, Streptococcus mitis group, Streptococcus oralis, Streptococcus pneumoniae, active against pathogens that are resistant to these antibiotics and these antibiotics may Streptococcus salivarius* be active against pathogens that are resistant to besifloxacin. In vitro studies demonstrated cross-resistance between besifloxacin and some fluoroquinolones. *Efficacy for this organism was studied in fewer than 10 infections. In vitro resistance to besifloxacin develops via multiple-step mutations and occurs 2 DOSAGE AND ADMINISTRATION at a general frequency of < 3.3 x 10-10 for Staphylococcus aureus and < 7 x 10-10 for Invert closed bottle and shake once before use. Streptococcus pneumoniae. Instill one drop in the affected eye(s) 3 times a day, four to twelve hours apart for 7 days. Besifloxacin has been shown to be active against most isolates of the following bacteria 4 CONTRAINDICATIONS both in vitro and in conjunctival infections treated in clinical trials as described in the None INDICATIONS AND USAGE section: 5 WARNINGS AND PRECAUTIONS Aerococcus viridans*, CDC coryneform group G, 5.1 Topical Ophthalmic Use Only NOT FOR INJECTION INTO THE EYE. Corynebacterium pseudodiphtheriticum*, C. striatum*, Haemophilus influenzae, Moraxella Besivance is for topical ophthalmic use only, and should not be injected subconjunctivally, catarrhalis*, M. lacunata*, Pseudomonas aeruginosa*, Staphylococcus aureus, S. nor should it be introduced directly into the anterior chamber of the eye. epidermidis, S. hominis*, S. lugdunensis*, S. warneri*, Streptococcus mitis group, S. oralis, S. pneumoniae, S. salivarius* 5.2 Growth of Resistant Organisms with Prolonged Use As with other anti-infec- tives, prolonged use of Besivance (besifloxacin ophthalmic suspension) 0.6% may result *Efficacy for this organism was studied in fewer than 10 infections. in overgrowth of non-susceptible organisms, including fungi. If super-infection occurs, 13 NONCLINICAL TOXICOLOGY discontinue use and institute alternative therapy. Whenever clinical judgment dictates, the 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies in patient should be examined with the aid of magnification, such as slit-lamp biomicrosco- animals to determine the carcinogenic potential of besifloxacin have not been performed. py, and, where appropriate, fluorescein staining. No in vitro mutagenic activity of besifloxacin was observed in an Ames test (up to 3.33 mcg/ 5.3 Avoidance of Contact Lenses Patients should not wear contact lenses if they plate) on bacterial tester strains Salmonella typhimurium TA98, TA100, TA1535, TA1537 have signs or symptoms of bacterial conjunctivitis or during the course of therapy with and Escherichia coli WP2uvrA. However, it was mutagenic in S. typhimurium strain TA102 Besivance. and E. coli strain WP2(pKM101). Positive responses in these strains have been observed 6 ADVERSE REACTIONS with other quinolones and are likely related to topoisomerase inhibition. Because clinical trials are conducted under widely varying conditions, adverse reaction Besifloxacin induced chromosomal aberrations in CHO cells in vitro and it was positive in an rates observed in one clinical trial of a drug cannot be directly compared with the rates in vivo mouse micronucleus assay at oral doses × 1500 mg/kg. Besifloxacin did not induce in the clinical trials of the same or another drug and may not reflect the rates observed in unscheduled DNA synthesis in hepatocytes cultured from rats given the test compound up practice. to 2,000 mg/kg by the oral route. In a fertility and early embryonic development study in The data described below reflect exposure to Besivance in approximately 1,000 patients rats, besifloxacin did not impair the fertility of male or female rats at oral doses of up to between 1 and 98 years old with clinical signs and symptoms of bacterial conjunctivitis. 500 mg/kg/day. This is over 10,000 times higher than the recommended total daily human ophthalmic dose. The most frequently reported ocular adverse reaction was conjunctival redness, reported in approximately 2% of patients. 14 CLINICAL STUDIES Other adverse reactions reported in patients receiving Besivance occuring in approximately In a randomized, double-masked, vehicle controlled, multicenter clinical trial, in which 1-2% of patients included: blurred vision, eye pain, eye irritation, eye pruritus and headache. patients 1-98 years of age were dosed 3 times a day for 5 days, Besivance was superior to its vehicle in patients with bacterial conjunctivitis. Clinical resolution was achieved in 45% 8 USE IN SPECIFIC POPULATIONS (90/198) for the Besivance treated group versus 33% (63/191) for the vehicle treated group 8.1 Pregnancy Pregnancy Category C. Oral doses of besifloxacin up to (difference 12%, 95% CI 3% - 22%). Microbiological outcomes demonstrated a statistically 1000 mg/kg/day were not associated with visceral or skeletal malformations in rat pups significant eradication rate for causative pathogens of 91% (181/198) for the Besivance in a study of embryo-fetal development, although this dose was associated with maternal treated group versus 60% (114/191) for the vehicle treated group (difference 31%, 95% toxicity (reduced body weight gain and food consumption) and maternal mortality. In- CI 23% - 40%). Microbiologic eradication does not always correlate with clinical outcome creased post-implantation loss, decreased fetal body weights, and decreased fetal ossifi- in anti-infective trials. cation were also observed. At this dose, the mean Cmax in the rat dams was approximately 20 mcg/mL, >45,000 times the mean plasma concentrations measured in humans. 17 PATIENT COUNSELING INFORMATION The No Observed Adverse Effect Level (NOAEL) for this embryo-fetal development study Patients should be advised to avoid contaminating the applicator tip with material from the eye, fingers or other source. was 100 mg/kg/day (Cmax, 5 mcg/mL, >11,000 times the mean plasma concentrations measured in humans). Although Besivance is not intended to be administered systemically, quinolones In a prenatal and postnatal development study in rats, the NOAELs for both fetal and administered systemically have been associated with hypersensitivity reactions, even maternal toxicity were also 100 mg/kg/day. At 1000 mg/kg/day, the pups weighed following a single dose. Patients should be advised to discontinue use immediately and significantly less than controls and had a reduced neonatal survival rate. Attainment of contact their physician at the first sign of a rash or allergic reaction. developmental landmarks and sexual maturation were delayed, although surviving pups Patients should be told that although it is common to feel better early in the course of from this dose group that were reared to maturity did not demonstrate deficits in behavior, the therapy, the medication should be taken exactly as directed. Skipping doses or not including activity, learning and memory, and their reproductive capacity appeared normal. completing the full course of therapy may (1) decrease the effectiveness of the immediate Since there are no adequate and well-controlled studies in pregnant women, Besivance treatment and (2) increase the likelihood that bacteria will develop resistance and will not should be used during pregnancy only if the potential benefit justifies the potential risk to be treatable by Besivance or other antibacterial drugs in the future. the fetus. Patients should be advised not to wear contact lenses if they have signs or symptoms of 8.3 Nursing Mothers Besifloxacin has not been measured in human milk, although bacterial conjunctivitis or during the course of therapy with Besivance. it can be presumed to be excreted in human milk. Caution should be exercised when Patients should be advised to thoroughly wash hands prior to using Besivance. Besivance is administered to a nursing mother. Patients should be instructed to invert closed bottle (upside down) and shake once before 8.4 Pediatric Use The safety and effectiveness of Besivance® in infants below one each use. Remove cap with bottle still in the inverted position. Tilt head back, and with year of age have not been established. The efficacy of Besivance in treating bacterial bottle inverted, gently squeeze bottle to instill one drop into the affected eye(s). conjunctivitis in pediatric patients one year or older has been demonstrated in controlled Manufactured by: Bausch & Lomb Incorporated clinical trials [see CLINICAL STUDIES (14)]. Tampa, Florida 33637 There is no evidence that the ophthalmic administration of quinolones has any effect on Besivance® is a registered trademark of Bausch & Lomb Incorporated. weight bearing joints, even though systemic administration of some quinolones has been ©Bausch & Lomb Incorporated shown to cause arthropathy in immature animals. U.S. Patent Nos. 6,685,958; 6,699,492; 5,447,926 8.5 Geriatric Use No overall differences in safety and effectiveness have been †DuraSite is a trademark of InSite Vision Incorporated observed between elderly and younger patients. 12 CLINICAL PHARMACOLOGY US/BES/15/0019 12.1 Mechanism of Action Besifloxacin is a fluoroquinolone antibacterial [see CLINI- Based on 9142605(flat)-9142705(folded) CAL PHARMACOLOGY (12.4)]. 12.3 Pharmacokinetics Plasma concentrations of besifloxacin were measured in adult patients with suspected bacterial conjunctivitis who received Besivance bilaterally three

RRO1215_BLO1215_BL BBesivanceesivance PPI.inddI.indd 1 111/18/151/18/15 2:552:55 PMPM Apr. 21, Birmingham, AL CE HOURS: 20 Apr. 29, Chicago Evening of Education LOCATION: Hyatt Hotel and Lexington ICO Resident Grand Rounds HOST: UAB School of Optometry Convention Center, 401 W. High St. HOST: Illinois College of CE HOURS: 2 CONTACT: Sarah Unger Optometry LOCATION: UAB School of [email protected] CE HOURS: 4 Optometry, 1716 University Blvd. 502-875-3516 LOCATION: Illinois College of CONTACT: Amanda Kachler www.kyeyes.org Optometry, 3241 S Michigan Ave. [email protected] CONTACT: Elizabeth Grantner 205-934-5701 Apr. 28-29, Grand Rapids, MI [email protected] www.uab.edu/optometry/ce Great Lakes Eyecare Conference 312-949-7426 HOST: Michigan Optometric www.ico.edu/alumni/continuing- Apr. 21-23, Las Vegas Association/Michigan College of education Mountain West Council of Optometry AL AM BV CM CL CD CS CT DE EL GL Optometrists Annual Congress CE HOURS: TBD LT NO NT IN PH RE SV SD TE UV HOST: MWCO LOCATION: DeVos Place, KEY FACULTY: Jay Haynie, Leo 303 Monroe Ave NW. Apr. 29-30, Howey-in-the-Hills, FL Semes, Michael Stewart, Scot Morris, CONTACT: Amy Root Florida Chapter-American Academy John McGreal, Jeff Sonsino [email protected] of Optometry CE HOURS: Total: 72, maximum per 517-482-0616 HOST: Florida Chapter-American OD: 24 www.themoa.org Academy of Optometry LOCATION: Aria Resort & Casino, KEY FACULTY: Paul Karpecki, Dave 3730 Las Vegas Blvd. S. Apr. 28-30, Oklahoma City, OK Woods, John McClane, Joe Pizzimenti, CONTACT: Tracy Abel OAOP Vision Summit Ben Lambright [email protected] HOST: Oklahoma Association of CE HOURS: Total: 16 (including 6 888-376-6926 Optometric Physicians HRS CE/TQ), Maximum per OD: 12 www.mwco.org KEY FACULTY: Nathan Lighthizer, (including 6 HRS CE/TQ) Steven Ferrucci, Ken Eakland, Bradley LOCATION: Mission Inn, AL CM CL DB DE GL NO IN PH PM RE Sutton 10400 County Road 48 RS SD UV CE HOURS: Total: 25, Maximum per CONTACT: Art Young OD: 18+ [email protected] Apr. 21-26, Niagara Falls, NY LOCATION: Renaissance Oklahoma 239-542-4627 Conference on Comprehensive City Convention Center Hotel, CD DE IN PH RE EyeCare 10 N. Broadway Ave. HOST: PSS EyeCare CONTACT: Heatherlyn Burton Apr. 29-May 1, Berkeley, CA KEY FACULTY: Ron Melton, Randall [email protected] Morgan Symposium - 31st Annual Thomas, Mile Brujic, William Jones, 405-524-1075 HOST: University of California, Elliot Kirstein, Deepak Gupta www.oaop.org Berkeley, School of Optometry CE HOURS: 18 AL AM CM CL CD CS DB DE GL PH PM KEY FACULTY: Carl Jacobsen, Todd LOCATION: Sheraton Hotel, 300 3rd St. RE RS SD TE UV Severin, Mark Dunbar, Joseph Sowka CONTACT: Sonia Kumari CE HOURS: 21 [email protected] Apr. 28-30 Topeka, KS LOCATION: DoubleTree Hotel, 203-415-3087 2016 Kansas Optometric Association Berkeley Marinann, 200 Marina Blvd. Annual Convention and Seminar www.psseyecare.com CONTACT: Danni Peck AL AM CM CL CD CS DB DE EL GL LT HOST: Kansas Optometric Association [email protected] CE HOURS: 13 NO NT IN PH PM RE RS SD 800-827-2163 LOCATION: Capitol Plaza Hotel, http://optometry.berkeley.edu/ce/ 1717 SW Topeka Blvd. Apr. 23-24, Brampton, Ontario, morgan-symposium CONTACT: Todd Fleischer Canada EL GL IN RE SD 45th Bi-Annual CE Seminar and [email protected] Optifair Canada Trade Show 785-232-0225 www.kansasoptometric.org Apr. 30-May 1, Dallas HOST: The Academy of Ophthalmic CE in the Southwest Education Apr. 28-May 1, Little Rock, AK HOST: University of Houston College KEY FACULTY: Mile Brujic 2016 Arkansas Optometric of Optometry & University of the CE HOURS: 14 Association Spring Convention Incarnate Word Rosenberg School of LOCATION: Embassy Grand HOST: Arkansas Optometric Optometry Convention Centre, 8800 Gore Rd. Association KEY FACULTY: Sandra Fortenberry, CONTACT: Claudia Marks, CE and CE HOURS: 20 Pat Segu Event Coordinator LOCATION: Little Rock Marriott, CE HOURS: 16 [email protected] 3 Statehouse Drive LOCATION: Westin Galleria Dallas, 905-731-6022 CONTACT: Vicki Farmer 13340 Dallas Parkway www.aoece.com [email protected] CONTACT: University of Houston 501-661-7675 College of Optometry Continuing Apr. 23-25, Lexington, KY arkansasoptometric.org Education Offi ce 2016 KOA Spring Congress [email protected] HOST: Kentucky Optometric AL CM CL CD CS CT DB DE GL NO IN 713-743-1900 Association PH PM RE RS UV http://ce.opt.uh.edu

REVIEW OF OPTOMETRY DECEMBER 15, 2015 33

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 3333 112/3/152/3/15 12:5812:58 PMPM Enjoy CE in Your Happy Place

ontinuing education need not be absorb Venice like a local? Absolutely got Ajamian and Maynard Pohl, and 20 hours all work and no play. Nowadays you covered. Visit Castello and have some of CE credit will be available. For more in- Cif you want to earn CE credits cicchetti,” he says. “We’ve been able to formation, contact Stuart Autry: sautry@ and have a vacation-worthy experience provide an outstanding vacation experi- tropicalce.com or go to www.tropicalce. at the same time, venues abound. But ence along with current, cutting-edge com. back when CE still meant sitting in an continuing education to the point that • New Technologies and Treatments anonymous lecture hall or the windowless many of the doctors who attend have in Vision Care – Bermuda: Join Review of box of a sterile classroom, optometrist traveled with us before.” Optometry and meeting chair Paul Kar- James Fanelli was brainstorming how to CE in Italy meetings begin with a re- pecki in Bermudaa fromfrom combine professional education, a visit to ception the evening before the fi rst day of June 9-12, and learnarn Italy and a personal touch that attendees continuing education. about the latest iinno-nno- would never forget. And so “CE in Italy” “We go to lengths to provide fare that vations in optometrymetry was born, cementing Dr. Fanelli as one is specifi c to the area, whether that’s wine, by a panel of expertsperts of the original pioneers in destination CE cheese or olives. And I provide an exten- who will help youu off erings. sive overview of the area, whether that is navigate how to “W“While I a region, such as Tuscany, or a small town, successfully inte-- was already such as Castiglion Fiorentino, where we grate these new invinvolvedo in have our Tuscany meeting and where I advances into a skisk con- live part-time.” your practice. ference,fere The education begins early, at 6:30am, Fourteen hours thethe idea to ensure attendees are free to enjoy the of CE credit will of bring- sights by the afternoon. be available. For ing CE to In addition to the usual meeting locales more information,n, contact Lois ItalyIt and like Florence, CE in Italy for 2016 will also DiDomenico: [email protected]@jobson.g@j EuropeE venture to Turin and the Piedmont region, com, or go to www.reviewofoptometry. wasw a home of Barolo and other memorable com/bermuda2016. thoughtt red wine varietals. Also new for 2016: a • Tropical CE – Disney 2016: Find your in program in Argentina for the avid hunter. inner Mouseketeer and earn CE credit in process “For duck hunters, the Holy Grail is Argen- Orlando, July 3-10, as Tropical CE hosts over severalseveral visits, usuallyusua tina because of the variety of species and a meeting at Disney’s Yacht Club Resort. alongsideldhl the typical Italianl af- sheer number of ducks.” Presenters include Mark Dunbar and Jill ternoon drink, an Aperol Spritz.” Whether it’s duck hunting, skiing, wine Autry. Twenty hours of CE credit can be The fi rst CE in Italy meeting tasting or setting sail aboard a cruise ship earned. For more information, contact was held in Florence, and has to tropical locations, here’s a round-up of Stuart Autry: [email protected] or since grown to six European destination CE off erings for 2016. go to www.tropicalce.com. meetings each year, three in the • Tropical CE – Napa 2016: Join Tropi- spring and three in the fall. Sunny Locales cal CE presenters Blair Lonsberry and What makes these meetings unique? • 2016 Island Eyes Conference: Soak David Kading at the Silverado Resort and Besides the beauty of Italy, Dr. Fanelli’s up the sun in beautiful Lahaina, Maui, Ha- Spa in Napa from Sept. 4-8 and earn up knowledge of the regions where the waii, from Jan. 17-23. This meeting, which to 14 CE hours. For more information, meetings take place helps make at- is hosted by Pacifi c University, will off er contact Stuart Autry: sautry@tropicalce. tendees’ stays even more enjoyable. For 29 hours of CE credit with presentations com or go to www.tropicalce.com. Dr. Fanelli, staple Italian attractions— the by Denise Goodwin, Nathan Lighthizer, Colosseum, the Vatican, Michelangelo’s Leo Skorin, Stanley Teplick and Samuel European Sightseeing David—are magnifi cent, but there’s so Kim. For more information, contact • CE in Italy – Turin: Join host James much more. And he should know. After Jeanne Oliver: jeanne@pacifi cu.edu or Fanelli, along with presenter Joe numerous trips, discussions around the go to www.pacifi cu.edu/islandeyes. Pizzimenti, in beautiful Turin from June dinner table with family based in Italy • Tropical CE – Riviera Maya 2016: Join 17-19 at the Victoria Hotel, where 12 credit and extended stays in his second home Diana Shechtman and William Miller Feb. hours will be available. Contact James outside of Florence, Dr. Fanelli possesses 13-20 in Playa Del Carmen, Mexico. The Fanelli: [email protected], www. the insider knowledge on local cuisine to meeting, hosted by Tropical CE, off ers 20 ceinitaly.com, for more information. aptly suggest restaurants and recom- hours of CE credit. For more information, • CE in Italy – Piedmont: This session mend signature dishes, down to which contact Stuart Autry: sautry@tropicalce. will take place June 21-23 at the Palazzo waiter to request at specifi c places. com or go to www.tropicalce.com. Righini; 12 CE credit hours will be avail- “What are the best beef and pasta • Tropical CE – Tahiti 2016: Beat the able. Joe Pizzimenti will present. Contact dishes in Florence? Got you covered. winter blues in Mo’orea and Bora Bora, James Fanelli: jamesfanelli@ceinitaly. What’s a good itinerary for Tuscany French Polynesia from March 4-12 with com, www.ceinitaly.com, for more infor- daytrips? Got that covered, too. Want to Tropical CE. Presenters include Paul mation.

34 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 34 12/3/15 1:01 PM • CE in Italy – Copenhagen, Denmark: The Great Outdoors tion and the Pennsylva-- Sept. 16-18, join James Fanelli, Leonard • Argentina Premier Duck Hunting nia Academy of Familyy Messner and Lorraine Lombardi at the Conference, Buenos Aires: Join James Physicians, this CE cruisese First Hotel Kong Frederik in Denmark. Fanelli on this exotic duck-hunting CE ad- features 12 hours of Twelve hours of CE will be available. venture from July 17-21, when 12 CE credit credit aboard the Royalal Contact James Fanelli: jamesfanelli@ hours can be earned. For more informa- Caribbean’s Grandeur of ceinitaly.com, www.ceinitaly.com. tion, contact James Fanelli, jamesfanelli@ the Seas. The ship leaveses • CE in Italy – Florence: James Fanelli ceinitalycom, www.ceinitaly.com. from Baltimore and sailsls and presenters Leonard Messner and • EyeFlyFish 2016: Get ready to tie to Bermuda from July 272-7. CContact Lorraine Lombardi will off er lectures at some fl ies during the EyeFlyFish 2016 Ilene Sauertieg: [email protected], the Hotel Silla in Florence from Sept. 20- conference, scheduled from Sept. 8-11 in or www.poaeyes.org. 22. Twelve hours of CE will be available. Alexandria, PA. Six CE credit hours will be • Western Mediterranean Cruise Contact James Fanelli: jamesfanelli@ available. For more information, contact Seminar: Sail from Barcelona, ceinitaly.com, www.ceinitaly.com. Charles Griff en: c.griff [email protected], July 3-10, and earn 10 CE • CE in Italy – Tuscany: Sept. 23-25, or go to www.eyefl yfi sh.com. credits. Contact Marge McGrath: at the Residence Le Santucce, attendees [email protected] or go to www. can hear from James Fanelli, Leonard CE at Sea optometriccruiseseminars.com. Messner and Lorraine Lombardi. Twelve • Western Caribbean Cruise: Sail • Western Mediterranean Cruise from hours of CE credit can be earned. Contact round-trip from Fort Lauderdale, Feb. Barcelona, A Clinical Compendium: James Fanelli: jamesfanelli@ceinitaly. 13-20, for Innovations in Eye Care, hosted Hosted by Dr. Travel Seminars, this cruise com, www.ceinitaly.com. by Dr. Travel Seminars. The key lecturer sails from July 3-10. Leo Semes is the key is Robert Wooldridge, and 16 CE credit presenter, and 12 CE credit hours will be The Pacific Rim hours can be earned. For more informa- available. For more information, contact • 2016 Imperial Japan CE, Tokyo: Join tion, contact Robert Pascal: drtravel@aol. Robert Pascal: [email protected], www. iTravelCE from Oct. 1-9 in Tokyo, where com or go to www.drtravel.com. drtravel.com. 18 hours of CE credit will be available. • Canary Islands Optometric Cruise • Stockholm to LLondonondon Optometrist Mile Brujic will present. Seminar: Sail from Barcelona, Spain, Feb. Optometric Cruiseise SemiSemi-- Contact Bridgitte Shen Lee: drbshenlee@ 14-24, aboard the NCL Epic and earn 10 nar: July 9-21, cruiseuise from itravelce.com, www.itravelce.com. CE credits. For more information, contact Stockholm to Londonondon Marge McGrath: [email protected] or aboard the Silversearsea Ski & CE Meetings go to www.optometriccruiseseminars. Silverwind, wherere 12 • SkiVision: Combining top quality com. CE hours can be CE with the thrills of alpine skiing can’t • Eastern Caribbean Optometric earned. Contact be beat. Join SkiVisionon and ReReviewview of CCruiseruise Seminar: Take Marge McGrath: Optometry from Feb.b. ttoo ththee seas Feb. 20-27 aeacruises@aol.. 12-16, along rround-tripound from Miami. Ten com or www. with presenters hourshours of CE are available. optometric- Murray Fingeret, For morem information, cruiseseminars. John Flanagan, contactcont Marge McGrath: com. Ian Ben Gaddie, [email protected] or • Greek Isles CCruiseruise ffromrom Jack Schaeff er, Jay ggoo tto www.optometric- Venice, Therapeuticutic AAdvancesdvances iinn OcuOcularlar Haynie and Kathy cruccruiseseminars.com. Disease 2016: Too be helheldd JJulyuly 2323-30,-30, jjoinoin Dumbleton, at the • Mediterranean Dr. Travel Seminars and hear lectures Westin Snowmass OptometricOp Cruise from renowned optometrist Ron Melton. Resort in Snowmass Seminar:Se Sail from Twelve hours of CE can be earned. Con- Village, CO, where youou BarcelonaB to Athens tact Robert Pascal: [email protected], can earn 20 CE credits.its. fromfrom AprilA 13-23 aboard www.drtravel.com. For more information,n, thethe SilverseaSilversea SilverwindSilverwin and earn 10 CE • Russia/Scandinavia Optometric contact Lois DiDomenico: ldidomenico@ credits.di For more iinformation, f contact Cruise Seminar: Earn 12 CE credits en jobson.com or go to www.skivision.com Marge McGrath: [email protected] or route from Amsterdam, July 25-Aug. 6, or www.reviewofoptometry.com. go to www.optometriccruiseseminars. aboard the Celebrity Silhouette. Contact • Eye Ski Conference, 30th Annual: com. Marge McGrath: [email protected] or Here’s another chance to hit the slopes, • Alaska Optometric Cruise Seminar: www.optometriccruiseseminars.com. this time, in Park City, Utah, from Feb. Climb aboard the Island Princess sailing • Dec. 24-31, Eastern Caribbean 28-March 4 at the Lodge at Mountain from Anchorage to Vancouver from June Cruise, A Day in My Retina Clinic: Hear Village. Key presenters include Joe Piz- 29-July 6. Ten CE credit hours are avail- from Jay Haynie, Dec. 24-31, aboard Nor- zimenti, Alan Berman, Leonard Messner able. For more information, contact Marge wegian Cruise Line’s Norwegian Escape, and James Fanelli. Twenty hours of CE McGrath: [email protected] or go to which departs from Miami. The seminar will be available. Contact Timothy Kime www.optometriccruiseseminars.com. is hosted by Dr. Travel Seminars. Contact at [email protected] or go to www. • POA/PAFP Seminar at Sea: Hosted Robert Pascal: [email protected], www. eyeskiutah.com. by the Pennsylvania Optometric Associa- drtravel.com.

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Sunday Monday Tuesday Wednesday Thursday Friday Saturday

1234567 ARVO Evidence Based Care MOA Annual Conference in Optometry 2016 Arkansas OA Spring Convention (begins Apr. 28) CE in the Southwest (begins Apr. 30) Morgan Symposium (begins Apr. 29) 8 9 10 11 12 13 14 University of MO International Vision Conference East Coding Update 2016 POA Spring Congress Indiana University CE

15 16 17 18 19 20 21 POA Spring Congress OEP Foundation VT/Visual Dysfunction Indiana University CE Oregon’s Meeting Potpourri of CE New Technologies and Treatments in Vision Care – San Antonio

22 23 24 25 26 27 28 OEP Foundation VT/ Visual Dysfunction Oregon’s Meeting New Tech San Antonio

29 30 31

May 1, Ellicott City, MD EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders Ninth Annual Evidence Based Care in AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Optometry Conference AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision HOST: Maryland Optometric BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease Association and Johns Hopkins CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology Wilmer Eye Institute CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis CE HOURS: TBD CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy LOCATION: Turf Valley Resort & Conf.

36 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 3636 112/3/152/3/15 1:021:02 PMPM CE HOURS: 16 MAY 1-5, SEATTLE LOCATION: IU School of Optometry 800 E. Atwater, Room 105 CONTACT: Cheryl Oldfi eld coldfi [email protected] 812-856-3502 ARVO 2016: A Vision for Hope www.opt.indiana.edu/ce/seminars.htm hen you think about the future understanding of the eye and visual May 15, Fullerton, CA Wof eye care, the Association processes. ARVO members are en- Potpourri of CE for Research in Vision and Ophthal- gaged in research that brings hope HOST: Marshall B. Ketchum University mology (ARVO) likely will come to to patients and their families that CE HOURS: 8 mind. As the nexus of pioneering treatments and cures for eye disease LOCATION: Marshall B. Ketchum work in ophthalmic research, ARVO are on the horizon. At the ARVO University will hold its annual meeting May 1-5, annual meeting, researchers from 2575 Yorba Linda Blvd. 2016, in Seattle with the theme “A around the world will come together CONTACT: Antoinette Smith Vision for Hope.” to explore cutting-edge science, [email protected] ARVO is the largest gathering of collaborate with peers and create 714-449-7495 www.ketchum.edu/index.php/ce eye and vision researchers in the connections between their work AL CL CS DB DE GL NO IN PE PH world, attracting more than 11,000 and the people who will ultimately RE SD attendees from more than 75 coun- benefi t from it. tries. Approximately 45% of ARVO’s The meeting will feature fi ve days May 18-22, Phoenix attendees are from outside the of innovative vision science covering VT/Visual Dysfunction United States. a range of topics including molecular HOST: OEP Foundation Biomedical research is behind biology, research, cornea, genetics, KEY FACULTY: Rob Lewis every advance in treatment for glaucoma, retina, nanotechnology CE HOURS: 35 blinding conditions, behind every and regenerative medicine, to name LOCATION: TBD improvement in diagnostic methods, a few. For more information or to CONTACT: Karen Ruder and behind all progression in the register, go to: www.arvo.org [email protected] 410-561-3791 www.oepf.org/oepf_calendar Center, 2700 Turf Valley Rd. CONTACT: Lis Ellerbusch AM BV VT CONTACT: Gala McCray [email protected] [email protected] 314-516-5615 May 19-22, Portland, OR 410-486-9662 PM Oregon’s Meeting marylandoptometry.org HOST: Oregon Optometric Physicians May 13-14, Pittsburgh Association May 1-5, Seattle International Vision Conference East KEY FACULTY: Winston Chamberlain, ARVO HOST: OD Excellence Afshan Nanji, John Clements, Mansi HOST: The Association of Research in KEY FACULTY: John McGreal, Paul Parikh, Eric Steele, Lori Lombardi CE HOURS: Total: 15, Maximum per Vision and Ophthalmology Chous, Jeff ry Gerson, Valerie Manso OD: 13 LOCATION: Washington State CE HOURS: 6 LOCATION: Sunriver Resort Convention Center, LOCATION: Hyatt Regency Pittsburgh 17600 Center Drive 800 Convention Place International Airport, 1111 Airport Blvd. CONTACT: Lynne Olson www.arvo.org CONTACT: Johanna Lieblein [email protected] [email protected] 800-922-2045 May 4-6, Missoula, MT 707-433-5542 www.oregonoptometry.org MOA Annual Conference & Exposition odexcellence.com CD CS CT GL IN RE RS HOST: Montana Optometric CD DB GL RE Association May 20-22, San Antonio, TX CE HOURS: 18 May 13-15, Camp Hill, PA New Technologies and Treatments in LOCATION: Hilton Garden Inn, POA Spring Congress Vision Care – San Antonio 3720 N Reserve St. HOST: PA Optometric Association HOST: Review of Optometry CONTACT: Sue Weingartner CE HOURS: 14 KEY FACULTY: Paul Karpecki [email protected] LOCATION: Radisson Hotel, (meeting chair) 406-443-1160 1150 Camp Hill Bypass CE HOURS: 17 www.mteyes.com CONTACT: Ilene K. Sauertieg LOCATION: San Antonio Marriott [email protected] Rivercenter, 101 Bowie St. May 9, St. Louis 717-233-6455 CONTACT: Lois DiDomenico Coding Update 2016 www.poaeyes.org [email protected] HOST: University of MO-St. Louis 866-658-1772 College of Optometry May 14-15, Bloomington, IN www.reviewofoptometry.com/ KEY FACULTY: John McGreal Indiana University CE sanantonio2016 CE HOURS: 4 HOST: IU School of Optometry CM CL DB DE EL GL IN PH RE

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000_1215_ceconference_final.indd 37 12/3/15 1:49 PM June

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

1234 OEP Foundation VT/Learning Related Visual Problems Alaska Optometric Association CE Congress Utah Optometric Association 2016 Congress Ocular Symposium: Pearls in Ocular Diagnosis Everything Theraputic: Houston

567891011 OEP Foundation VT Indiana Health Service: Biennial Healthcare Meeting Pacific U. Northwest Residents Conference Alaska OA North Carolina State Spring Congress CE Congress OEP Foundation VT/Learning Related Visual Problems Utah Optometric Association 2016 Congress OEP Foundation Art + Science of Optometric Care Ocular Symposium: Pearls in Ocular Virginia Optometric Association Annual Conference Diagnosis Georgia Optometric Association Annual Meeting Everything New Technologies & Treatments in Vision Care – Bermuda Theraputic: Houston Dual Sensory Loss NOA Clinical Update 12 13 14 15 16 17 18 NC State Spring Cong. Optometry Association of Louisiana Annual Convention OEP VT CE in Italy – Turin OEP Art + Science of Optometric Care VOA Annual Conf. GOA Annual Meeting New Tech – Bermuda UC Berk. Res. Forum 19 20 21 22 23 24 25 Optometry Assn. CE in Italy – Piedmont OEP Foundation of Louisiana The OD’s Guide to Annual Convention Strabismus CE in Italy – Turin

26 27 28 29 30 OEP Foundation AOA – Optometry’s Meeting (ends Jul. 3) The OD’s Guide to Strabismus AEA Cruises Alaska Optometric Cruise Seminar (ends Jul. 6)

Jun. 1-5, Ft. Lauderdale EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders VT/Learning Related Visual Problems AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery HOST: OEP AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision KEY FACULTY: Rob Lewis BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease CE HOURS: 35 CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology LOCATION: Nova Southeastern CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis University College of Optometry, CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy 3301 College Ave.

38 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 3838 112/3/152/3/15 1:021:02 PMPM CONTACT: Karen Ruder; 410-561-3791 HOST: Marshall B. Ketchum University Jun. 9-12, Amelia Island, FL [email protected] CE HOURS: 25 Georgia Optometric Association www.oepf.org/oepf_calendar LOCATION: Marshall B. Ketchum Annual Meeting AM BV VT University, 2575 Yorba Linda Blvd. HOST: Georgia Optometric Assn. CONTACT: Antoinette Smith CE HOURS: 15 Jun. 2-5, Homer, AK [email protected] LOCATION: Omni Amelia Island Alaska Optometric Assn. CE Congress 714-449-7495 Plantation Resort, HOST: AKOA www.ketchum.edu/index.php/ce 39 Beach Lagoon Rd. CE HOURS: 22 AL AM BV CD CS DB DE GL LT NO IN CONTACT: Vanessa Grosso LOCATION: Lands End Resort, PE PH RE RS SD UV [email protected] 4786 Homer Spit Rd. 770-961-9866 x-1 CONTACT: Lisa Johnson Jun. 6-12, Myrtle Beach, SC www.goaeyes.com [email protected] Spring Congress GL NO IN PH SD 907-770-3777 HOST: North Carolina State akoa.org Optometric Society Jun. 9-12, Hamilton, Bermuda CE HOURS: 18 New Technologies and Treatments in Jun. 2-6, Midway, UT LOCATION: Embassy Suites Kingston Vision Care – Bermuda 2016 Annual Congress Plantation, 9800 Kingsway Blvd. HOST: Review of Optometry HOST: Utah Optometric Association CONTACT: Adrianne Drollette KEY FACULTY: Paul Karpecki, Ben CE HOURS: 18 [email protected] Gaddie, Marc Bloomenstein, Mark LOCATION: TBD 919-977-6964 Dunbar, Doug Devries, Jack Schaeff er CONTACT: Alyssa White www.nceyes.org CE HOURS: 14 [email protected] LOCATION: Hamilton Princess & Beach 801-364-9103 Jun. 8-12, Listowel, Ontario, Canada Club, 79 Pitts Bay Rd. www.utaheyedoc.org VT/Learning Related Visual Problems CONTACT: Lois DiDomenico HOST: OEP Foundation [email protected] Jun. 3-5, San Francisco KEY FACULTY: Robert Hohendorf 866-658-1772 Ocular Symposium: Pearls in Ocular CE HOURS: 35 www.reviewofoptometry.com/ Diagnosis LOCATION: Listowel, Ontario, Canada bermuda2016 HOST: Ocular Symposium CONTACT: Karen Ruder CM DE EL GL IN PH RE KEY FACULTY: H. Richard McDonald, [email protected] David F. Chang, Andrew G. Iwach, 410-561-3791 Jun. 10, Wichita, KS Rona Z. Silkiss, Marc Levin, William F. www.oepf.org/oepf_calendar Dual Sensory Loss Good AM BV VT HOST: Envision University CE HOURS: 24 KEY FACULTY: Walter Wittich LOCATION: Holiday Inn Golden Jun. 8-12, Burlington, Ontario, CE HOURS: 4 Gateway, 1500 Van Ness Ave. Canada LOCATION: Envision, 610 N. Main CONTACT: Lorraine Geary The Art + Science of Optometric Care CONTACT: Michael Epp [email protected] HOST: OEP Foundation [email protected] 415-278-9940 KEY FACULTY: Steen Aalberg 326-440-1515 CS CT GL NO IN PE RE RS SD UV VT CE HOURS: 35 www.envisionuniversity.org LOCATION: Burlington, Ontario, NO VT Jun. 4-5, Houston Canada Everything Therapeutic: Houston CONTACT: Karen Ruder Jun. 10-11, Forest Grove, OR HOST: University of Houston College [email protected] Northwest Residents Conference of Optometry 410-561-3791 HOST: Pacifi c University College of KEY FACULTY: Bruce Onofrey www.oepf.org/oepf_calendar Optometry CE HOURS: 16 AM BV VT KEY FACULTY: 21 residents from LOCATION: Health and Biomedical affi liated programs in MN, NV, OR, PA Sciences Building at the University of Jun. 9-12, Hot Springs, VA and WA Houston College of Optometry, VOA Annual Convention CE HOURS: 10.5 4901 Calhoun Rd. HOST: Virginia Optometric Association LOCATION: Pacifi c University Campus, CONTACT: University of Houston CE HOURS: 18-20, Maximum per OD: Jeff erson Hall, 2221 Pacifi c Ave. College of Optometry CE Offi ce 16 CONTACT: Martina Fredericks [email protected] LOCATION: Omni Homestead Resort, frederim@pacifi cu.edu 713-743-1900 7696 Sam Snead Hwy. 503-352-2207 http://ce.opt.uh.edu CONTACT: Bo Keeney, Executive www.pacifi cu.edu/future-graduate- Director professional/colleges/college- Jun. 6-9, Fullerton, CA offi [email protected] optometry/continuing-education Indian Health Service: 804-643-0309 AL AM BV CM CL CD CS CT DB DE EL Biennial Healthcare Meeting www.thevoa.org GL NO IN PE PH RE RS SD UV

REVIEW OF OPTOMETRY DECEMBER 15, 2015 39

0000_1215_ceconference_final2.indd00_1215_ceconference_final2.indd 3939 112/4/152/4/15 10:2210:22 AMAM JUNE 29-JULY 3, BOSTON

Historic Boston to Host Optometry’s Meeting he city of Boston is the place to Tbe for the 119th annual American Optometric Association (AOA) Con- gress and the 46th Annual American Optometric Student Association (AOSA) Conference. Better known as “Optometry’s Meeting,” the congress will be held from June 29 to July 3 at the Boston Convention and Exhibi- tion Center. Registration and housing will open in early February. The conference will off er a total of 180 continuing education hours, with 36 maximum hours per OD. During the fi ve-day congress, attendees will sites, including the Old South Meet- the pioneering civil rights work of be able to partake of educational ing House, Bunker Hill Monument and Boston’s free African American sessions on a broad array of topics the Paul Revere House, and covers community, which led the nation in that run the gamut from traditional to two-and-a-half centuries of America’s the movement to end slavery and cutting-edge optometric care. past. achieve equal rights; and the Irish “As always, we are planning a top- You can take a self-guided tour Heritage Trail (www.irishheritagetrail. notch experience for our attendees or one of the many tours available com), which guides visitors to land- at Optometry’s Meeting this June in through the National Park Service marks of Irish-American artists and Boston,” says AOA president Steven (www.nps.gov/bost/planyourvisit/ heroes from the 1700s to the present. Loomis, OD, who notes that the guidedtours.htm), the Boston Com- • Walk the JFK Trail: Visit historic meeting will provide “the right tools mon Visitors Center at 148 Tremont sites frequented by the late President to guide your practice to the solu- Street, or the Bostix Booth in Faneuil John F. Kennedy. The GPS tour can tions that will drive future success.” Hall. If you prefer to ride, you can pay be downloaded to your cell phone By attending, he says, you’ll “benefi t for one of the trolley tours, which are or other mobile device. www. your career, advance your knowledge unoffi cial guided tours, but take rid- boston.com/travel/boston/gallery/ and better position yourself for future ers to many of the sites along the trail jfkgpstour success.” and allow for stops at selected sites. • Explore the Boston Sports Trail: For further details as they come To fi nd out more about guided tours, Whether you like hockey or baseball, available, check the AOA’s website, contact the Greater Boston Con- get your sports fi x even on off -days www.optometrysmeeting.org. vention and Visitors Bureau (www. by visiting stops along the Boston Have questions or want to bostonusa.com). Sports Trail, including Fenway Park, register? Contact Stacy Harris at • Explore Boston Heritage Trails: Agganis Arena and the Boston Com- [email protected] or go to www. Complementary to the Freedom mon. Also available for download. optometrysmeeting.org. Trail, Boston Heritage Trails explore www.geovative.com/GeoTours/ the rich cultures of diff erent groups tourView.asp?6174Vq=LIGE “One if by land…” throughout Boston’s history. Tours • The Rose Kennedy Greenway While at the AOA meeting, be sure are self-guided or conducted by tour Walking Tour: With more than a to embark on one of Boston’s many guide, with maps available online. mile-and-a-half of public parkland, historic trails to get an insider’s look The trails include: Women’s Heri- the Rose Kennedy Greenway makes at the city at its best. Its compact size tage Trail (http://bwht.org), which for a great walk in downtown Boston. and historic neighborhoods are per- highlights the work of Boston women www.rosekennedygreenway.org/ fect for both long and leisurely strolls. like Abigail Adams, Phillis Wheatley, visit/tours • Walk the Freedom Trail: One Amelia Earhart, Louisa May Alcott, • Climb Bunker Hill Monument: of the nation’s fi rst historic walk- and Rose Kennedy; Boston’s Black “Don’t fi re until you see the whites of ing tours, the trail—marked by a red Heritage Trail (www.afroammuseum. their eyes!” This legendary order has line—takes the visitor to 16 historical org/trail.htm), which recognizes (continued on page 43)

40 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 40 12/3/15 1:50 PM Lacrisert is a trademark of Valeant Pharmaceuticals InterUH[PVUHS0UJVYP[ZHMÄSPH[LZ Bausch + Lomb is a trademark of Bausch & Lomb Incorporated or its affiliates. ©2014 Bausch & Lomb Incorporated US/LAC/14/0008b

CCP1215_BLP1215_BL LLacrisert.inddacrisert.indd 1 111/24/151/24/15 10:0410:04 AMAM CP1215_BL Lacrisert PI.indd 1 11/24/15 10:06 AM LOCATION: Victoria Hotel (continued from page 40) Chow—Beyond Chowder CONTACT: James Fanelli come to symbolize determination of Boston cuisine has long surpassed [email protected] the ill-equipped American colonists the days of just baked beans and 910-452-7225 facing powerful British forces during chowder. Drop your “R”s and discover www.ceinitaly.com the famous battle fought on this site your true Yankee palate at these Yelp CM CD CT EL GL IN RE on June 17, 1775. Ascend the 294 recommendations for Boston: steps to the top of the monument for • Piperi Mediterranean Grill Jun. 21-23, Piedmont, Italy great views of Boston. www.nps.gov/ One Beacon St. CE in Italy bost/learn/historyculture/bhm.htm www.piperi.com HOST: James Fanelli • Discover Boston Parks: From the • Giacamo’s Ristorante KEY FACULTY: Joseph Pizzimenti Boston Common and Public Gardens 355 Hanover St. to Franklin Park, there are plenty of CE HOURS: 12 http://giacomosblog-boston. LOCATION: Palazzo Righini green spaces to explore while in Bos- blogspot.in ton. www.cityofboston.gov/parks/ CONTACT: James Fanelli • The Salty Pig emerald [email protected] 130 Dartmouth St. • Take a Walk to the Sea: Boston’s 910-452-7225 www.thesaltypig.com Walk to the Sea trail encompasses www.ceinitaly.com • Neptune Oyster four centuries of Boston history. Mix- CM CD DB GL RE UV 63 Salem St. ing historical landmarks with Boston’s www.neptuneoyster.com skyscrapers, this walk is truly one Jun. 25-26, Burlington, Ontario, • Asta, 47 Massachusetts Ave. worth taking. The walk from summit Canada www.astaboston.com to sea—spanning one mile and de- The Optometrist’s Guide to Strabismus scending a hundred feet—brings that • Menton HOST: Patricia Fink and OEP history to life. www.walktothesea. 354 Congress St. Foundation com/index.html www.mentonboston.com KEY FACULTY: Samantha Slotnick • Self-guided Audio Tours: • Toro, 1704 Washington St. LOCATION: 2080 Appleby Line, Let your mobile device be your www.toro-restaurant.com Ste. E6 tour guide in these free audio • Ostra CONTACT: Karen Ruder tours: Boston Harborwalk (www. 1 Charles St. South [email protected] audisseyguides.com/boston-the- www.ostraboston.com 410-561-3791 harborwalk), Fort Point Harbor • Island Creek Oyster Bar www.oepf.org/oepf_calendar (www.audisseyguides.com/ 500 Commonwealth Ave. AM BV VT boston-the-fort-point-channel- www.islandcreekoysterbar.com neighborhood) and Boston Public • Mike & Patty’s Jun. 29-July 3, Boston Garden (www.audisseyguides.com/ 12 Church St. AOA, Optometry’s Meeting tour-overview-6). www.mikeandpattys.com HOST: American Optometric Association and the American Jun. 11, Omaha, NE [email protected] Optometric Student Association Clinical Update Conference 800-827-2163 CE HOURS: Total: 180, Maximum per HOST: Nebraska Optometric http://optometry.berkeley.edu/ce/ OD: 36 Association morgan-symposium LOCATION: Boston Convention and KEY FACULTY: Kyle Cheatham, GL IN SD Exhibition Center, 415 Summer St. Christopher Wolfe CONTACT: Stacy Harris CE HOURS: 8 Jun. 17-19, Baton Rouge, LA [email protected] LOCATION: Sheraton Omaha, OAL Annual Convention 314-983-4254 655 N. 108th Ave. HOST: Optometry Association of www.optometrysmeeting.org CONTACT: David S. McBride Louisiana AL AM BV CM CL CD CS CT DB DE EL dmcbride@assocoffi ce.net CE HOURS: 16 GL NO NT IN DS PE PH PM RE RS SV 402-474-7716 LOCATION: Crowne Plaza Hotel, SD TE UV VT www.noaonline.org 4728 Constitution Ave. AM CD DE EL NO IN PH RE SD UV CONTACT: Jim Sandefur Jun. 29-Jul. 6, Anchorage [email protected] to Vancouver Jun. 12, Berkeley, CA 318-613-1392 AEA Cruises Alaska Optometric Resident Forum www.optla.org Cruise Seminar HOST: University of California, HOST: AEA Cruises Berkeley, School of Optometry Jun. 17-19, Turin, Italy CE HOURS: 10 KEY FACULTY: On-Campus and CE in Italy LOCATION: Aboard Island Princess Affi liate VA Residents HOST: James Fanelli CONTACT: Marge McGrath CE HOURS: 7 KEY FACULTY: James Fanelli, Joseph [email protected] LOCATION: UC Berkeley Campus Pizzimenti 888-638-6009 CONTACT: Danni Peck CE HOURS: 12 www.optometriccruiseseminars.com

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0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 4343 112/3/152/3/15 1:031:03 PMPM July

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

12 AOA – Optometry’s Meeting (begins Jun. 29) AEA Cruises Alaska Optometric Cruise Seminar (begins Jun. 29) POA/PAFP Seminar at Sea

3456789 PA Optometric Association/PA Academy of Family Physicians Seminar at Sea Ocular Disease: Part II AEA Cruises Western Mediterranean Cruise Seminar Cruise from Barcelona – A Clinical Compendium Tropical CE – Disney 2016 AEA Cruises Alaska Optometric Cruise Seminar Stockholm to London Optometric Cruise Optometry’s Meeting Seminar RSO CE on the Beach

10 11 12 13 14 15 16 AEA Cruises Stockholm to London Optometric Cruise Seminar Ocular Disease: Part II IOA Summer Seminar Colorado Vision Summit Western Mediterranean 2016 FOA Annual Convention Cruise Seminar Barcelona Cruise – A Clinical Compendium Tropical CE – Disney 2016 RSO CE on the Beach 17 18 19 20 21 22 23 AEA Cruises Stockholm to London Optometric Cruise Seminar Greek Isles Cruise – Therapeutic Advances Argentina Premier Duck Hunting Conference in Ocular Disease 2016 Colorado Vision Pacific U. 2016 Victoria Conference Summit U. of Houston CE in the Rockies 2016 FOA Annual Convention Envision Low Vision Grand Rounds

24 25 26 27 28 29 30 Greek Isles Cruise – Therapeutic Advances in Ocular Disease 2016 Pacific U. 2016 AEA Cruises Russia/Scandinavia Optometric Cruise Seminar Victoria Conference Northern Rockies Optometric Conference U. of Houston CE in the Rockies OEP Foundation VT/Strabismus + Amblyopia NC State Mountain District Meeting

31 AEA Cruises Russia/Scandinavia Optometric Cruise Seminar (ends Aug. 6) OEP Foundation VT/Strabismus + Amblyopia

44 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 4444 112/3/152/3/15 1:041:04 PMPM Jul. 2-7, Bermuda Jul. 9-10, Fullerton, CA Jul. 14-17, Steamboat Springs, CO POA/PAFP Seminar at Sea Ocular Disease: Part II Colorado Vision Summit HOST: Pennsylvania Optometric Assn., HOST: Marshall B. Ketchum University HOST: Colorado Optometric PA Academy of Family Physicians KEY FACULTY: George Comer, David Association/Mountain States CE HOURS: 12 Sendrowski and more Congress of Optometry LOCATION: Aboard Royal Caribbean’s CE HOURS: 16 KEY FACULTY: Eric Schmidt, Gregory Grandeur of the Seas, departs from LOCATION: Marshall B. Ketchum Schultz, Catherine McDaniel, William Baltimore University, 2575 Yorba Linda Blvd. Townsend, Michelle Buckland CONTACT: Ilene K. Sauertieg CONTACT: Antoinette Smith CE HOURS: Total: 54, Maximum per [email protected] [email protected] OD: 18 717-233-6455 714-449-7495 LOCATION: Steamboat Grand and www.poaeyes.org www.ketchum.edu/index.php/ce Steamboat Sheraton, 2300 Mt. AM CL CD DB DE GL NO IN PE PH RE Werner Circle/2220 Village Inn Court Jul. 3-10, Barcelona SD TE UV CONTACT: Tara Weghorst AEA Cruises Western Mediterranean [email protected] Cruise Seminar Jul. 9-10, South Padre Island, TX 303-863-9268 HOST: AEA Cruises CE on the Beach (Schlitterbahn visioncare.org CE HOURS: 10 South Padre Island) BV EL GL NO IN PE SV VT LOCATION: Aboard NCL Epic HOST: Rosenberg School of CONTACT: Marge McGrath Optometry Jul. 14-17, Palm Beach, FL [email protected] CE HOURS: 16 2016 FOA Annual Convention 888-638-6009 LOCATION Rosenberg School of HOST: Florida Optometric Association www.optometriccruiseseminars.com Optometry, 9725 Datapoint Dr. CE HOURS: Total: 30, Maximum per CONTACT: Sandra Fortenberry OD: 22 Jul. 3-10, Western Mediterranean [email protected] LOCATION: The Breakers Palm Beach, Cruise from Barcelona – 210-283-6856 1 South Country Rd. A Clinical Compendium www.uiw.edu/optometry/continuing- CONTACT: Jessica Brewton HOST: Dr. Travel Seminars education jessica@fl oridaeyes.org KEY FACULTY: Leo Semes 850-877-4697 CE HOURS: 12 Jul. 9-21, Stockholm to London www.fl oridaeyes.org/calendar LOCATION: Aboard Royal Caribbean’s AEA Cruises Stockholm to London Harmony of the Seas, Western Optometric Cruise Seminar Jul. 17-21, Buenos Aires, Argentina Mediterranean sailing from Barcelona HOST: AEA Cruises Argentina Premier Duck Hunting CONTACT: Robert Pascal CE HOURS: 12 Conference [email protected] LOCATION: Aboard Silversea HOST: James Fanelli, CE in Italy 800-436-1028 Silverwind KEY FACULTY: James Fanelli www.DrTravel.com CONTACT: Marge McGrath CE HOURS: 12 GL IN PH RE [email protected] LOCATION: Buenos Aires and Duck 888-638-6009 Hunters Paradise, Argentina Jul. 3-10, Orlando www.optometriccruiseseminars.com David Denies Outfi tters Tropical CE – Disney 2016 CONTACT: James Fanelli HOST: Tropical CE Jul. 13, Carmel, IN [email protected] KEY FACULTY: Mark Dunbar, Jill Autry IOA Summer Seminar 910-452-7225 CE HOURS: 20 HOST: Indiana Optometric Association www.ceinitaly.com LOCATION: Disney’s Yacht Club CE HOURS: 7 CM LT NO IN SD Resort, 1700 Epcot Resorts Blvd. LOCATION: Ritz Charles, CONTACT: Stuart Autry 12156 N. Meridian St. Jul. 21, Wichita, KS [email protected] CONTACT: Bridget Sims Low Vision Grand Rounds – An 281-808-5763 [email protected] Evening with the Fellows www.TropicalCE.com 317-237-3560 HOST: Envision University AL CM CD DE GL PH RE www.ioa.org KEY FACULTY: Laura Walker EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders CE HOURS: 2 AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery LOCATION: Envision, 610 N. Main AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision CONTACT: Michael Epp BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease [email protected] CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology 326-440-1515 CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis www.envisionuniversity.org CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy BV NO RE VT

REVIEW OF OPTOMETRY DECEMBER 15, 2015 45

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 4545 112/3/152/3/15 1:051:05 PMPM Melton & Thomas — Straight Talk from the Experts Like all memorable duos, it’s hard to separate optometry’s most enduring partnership. Ron Melton, OD, and Randall Thomas, OD, have become legends on the lecture circuit for their innovative “team teaching” model and folksy, straight- talking presentation style. Spend any time with the pair and you know the quips are sure to fl y fast. But don’t let that fool you. The recipients of the 2014 American Academy of Optometry Clinician Educators Annual Award have been in full-time clinical practice for a combined 70+ years and provide state-of-the-art, clinically relevant knowledge grounded in peer-reviewed optometric and ophthalmologic research. Their entertaining delivery style and sound clinical advice garner rave reviews. To date, the duo have presented more than 1,000 courses and lectures throughout the world. At press time, here’s where Drs. Melton and Thomas are slated to appear in 2016:

Date Location Conference For More Info Overheard in the Jan. 16 Ft. Lauderdale Gold Coast Lori Vollmer, OD Lecture Hall… Educational Retreat [email protected] Here’s what some ODs who Broward County browardeyes.org attended the Melton & Thomas Optometric Assn. “Eye to Eye” meetings in 2015 had Jan. 23 Ventura, CA Tri-County Morgan Ruiz, OD to say about the experience: Optometric Society [email protected] tcosvision.org Feb. 27-28 Atlanta SECO Elizabeth Taylor DeMayo I love these guys. I learn etaylor@secostaff .com www.seco2016.com more from their CEs in three Mar. 19 Tyson’s Corner, PSS EyeCare Meeting Deepak Gupta, OD hours than 20 hours of other VA [email protected] CE. Please never stop book- www.psseyecare.com ing these guys for lectures! Mar. 22 Raleigh, NC Eastern District of Sean Smolenyak, OD NC State Optometric [email protected] Association www.nceyes.org Apr. 16 New York Vision Expo East Judy Weaver [email protected] www.visionexpoeast.com I would attend any Melton/ Apr. 17 Indianapolis Indiana Optometric Barbara McNutt Thomas talk—very informa- Association [email protected] tive and hours go by quickly.

Apr. 23 Niagara Falls, NY PSS EyeCare Meeting Deepak Gupta, OD [email protected] www.psseyecare.com Jun. 29 Boston American Optometric Stacy Harris Great material overview Association [email protected] and presentation. We all are www.optometrysmeeting. blessed to be here today! org Thank God for these guys! Jul. 29 TBD Mountain District Susanne Kilgo Meeting of the NC [email protected] State Optometric www.nceyes.org Association Jul. 23-31 Greek Isles Sail the Greek Isles Robert Pascal (with Ron Melton) with Dr. Melton [email protected] Always enjoy Ron and Ran- www.drtravel.com dall giving these updates. Sept. 17 Las Vegas Vision Expo West Judy Weaver Their no-nonsense, bottom [email protected] line, clinically relevant lec- www.visionexpowest.com tures are always enlightening. Sept. 24 Sarasota, FL CE Sarasota Julie Peirce Symposium [email protected]

Oct. 8 Cleveland EastWest Annual Brian Mathie Please return to Dallas for Conference [email protected] CE every year! www.eastwesteye.org Nov. 12 Anaheim, CA American Academy Jenny Brown of Optometry [email protected] www.aaopt.org

46 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 46 12/3/15 1:05 PM Jul. 21-24, Victoria, British Columbia Jul. 23-30, Greek Isles Cruise CE HOURS: 16 2016 Victoria Conference Therapeutic Advances in Ocular LOCATION: Snow King Hotel and HOST: Pacifi c University Disease 2016 Resort, 400 E Snow King Ave. KEY FACULTY: Kathleen Elliott, HOST: Dr. Travel Seminars CONTACT: Kari Cline Amber Giannoni, Jeff rey Urness, John KEY FACULTY: Ron Melton [email protected] McGreal CE HOURS: 12 307-640-6157 CE HOURS: 20 LOCATION: Norwegian Jade, Greek www.nrocmeeting.com LOCATION: Delta Ocean Pointe Isles sailing from Venice Resort, 45 Songhees Rd. CONTACT: Robert Pascal Jul. 28-31, Grand Rapids, MI CONTACT: Jeanne Oliver [email protected] VT/Strabismus + Amblyopia jeanne@pacifi cu.edu 800-436-1028 HOST: OEP Foundation 503-352-2740 www.DrTravel.com KEY FACULTY: Robert Hohendorf www.pacifi cu.edu/future-graduate- CD DB GL IN PH RE SD UV CE HOURS: 28 professional/colleges/college- LOCATION: South Kent Vision Center, optometry/continuing-education/ Jul. 25-Aug. 6, Amsterdam 3977 Maple St. SW conferences-events AEA Cruises Russia/Scandinavia CONTACT: Karen Ruder CD CS DE GL NT PE PH RS TE Optometric Cruise Seminar [email protected] HOST: AEA Cruises 410-561-3791 Jul. 21-24 Estes Park, CO CE HOURS: 12 www.oepf.org/oepf_calendar CE in the Rockies LOCATION: Aboard Celebrity AM BV VT HOST: University of Houston College Silhouette of Optometry CONTACT: Marge McGrath Jul. 29, (Location TBD) KEY FACULTY: Danica Marrelli [email protected] NC Mountain District Meeting CE HOURS: 20 888-638-6009 HOST: NC State Optometric Assn. LOCATION: Rocky Mountain Park Inn, www.optometriccruiseseminars.com KEY FACULTY: Ron Melton, Randall 101 South Saint Vrain Ave. Thomas CONTACT: University of Houston Jul. 27-30, Jackson, WY CE HOURS: TBD [email protected] Northern Rockies Optometric Conf. CONTACT: Susan Kilgo 713-743-1900 HOST: Northern Rockies Optometric [email protected] http://ce.opt.uh.edu Conference www.nceyes.org

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Sunday Monday Tuesday Wednesday Thursday Friday Saturday

123456 AEA Cruises Russia/Scandinavia Optometric Cruise Seminar (begins Jul. 25) RSO CE Abroad SWFOA Educational Retreat OEP Foundation Diagnosis, Management and Treatment of Brain Injury Patients Indiana University CE

78910111213 SWFOA Educational AAO NJ Chapter CE Retreat OEP Diagnosis, Mgmt. and Treatment of Brain Injury Patients Indiana University CE

14 15 16 17 18 19 20 International Vision Conference West

21 22 23 24 25 26 27 SCOPA Annual Meeting UAB Continuing Education & Alumni Weekend

28 29 30 31 SCOPA Annual Meeting UAB Continuing Education & Alumni Weekend

Aug. 2-5, Heidelberg, Germany Aug. 5-7, Captiva Island, FL Association CE Abroad SWFOA Educational Retreat KEY FACULTY: Bruce Onofrey, Kim HOST: Rosenberg School of HOST: Southwest Florida Optometric Reed, April Jasper, Ron Foreman Optometry CE HOURS: 20 EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders LOCATION: Rosenberg School of AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Optometry, 9725 Datapoint Dr. AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision BV Binocular vision CONTACT: Sandra Fortenberry DE Dry eye DS Optical dispensing SD Systemic disease CM Comanagement [email protected]; 210-283-6856 EL Eyelids/adnexa PE Pediatric eye care TE Technology CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis www.uiw.edu/optometry/continuing- CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy education

48 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 4848 112/3/152/3/15 1:061:06 PMPM CE HOURS: Total: 20 (including 6 LOCATION: IU School of Optometry, [email protected] HRS CE/TQ), Maximum per OD: 18 800 E. Atwater Ave., Room 105 707-433-5542 (including 6 HRS CE/TQ) CONTACT: Cheryl Oldfi eld odexcellence.com LOCATION: South Sea Island Resort, coldfi [email protected] CD DB GL RE 5400 Plantation Rd. 812-856-3502 CONTACT: Brad Middaugh www.opt.indiana.edu/ce/seminars. Aug. 25-28, Hilton Head, SC [email protected] htm 109th SCOPA Annual Meeting 239-481-7799 HOST: South Carolina Optometric www.swfoa.com Aug. 10, Neptune, NJ Physicians Association CD EL NT IN PH PM SD AAO - NJ Chapter CE CE HOURS: 21 HOST: American Academy of LOCATION: Westin Resort and Spa, Aug. 5-7, Timonium, MD Optometry – New Jersey Chapter 2 Grasslawn Ave. ABI/TBI – Diagnosis, Management CE HOURS: 6 CONTACT: Jackie Rivers and Treatment of Brain Injury Patients LOCATION: Jumping Brook Country [email protected] HOST: OEP Foundation Club, 210 Jumping Brook Road 803-799-6721 KEY FACULTY: Paul Harris CONTACT: Dennis Lyons www.sceyedoctors.com CE HOURS: 21 [email protected] LOCATION: OEP National Education 732-920-0110 Aug. 26-28, Birmingham, AL Center, 2300 York Rd., Suite 113 CONTACT: Karen Ruder Aug. 19-20, Burlingame, CA Continuing Education & Alumni [email protected] International Vision Conference West Weekend 410-561-3791 HOST: OD Excellence HOST: UAB School of Optometry www.oepf.org/oepf_calendar KEY FACULTY: John McGreal, Paul CE HOURS: 18 BV NO VT Chous, Jeff ry Gerson, Valerie Manso LOCATION: UAB School of CE HOURS: 6 Optometry, 1716 University Blvd. Aug. 6-7, Bloomington, IN LOCATION: Hyatt Regency San CONTACT: Amanda Kachler Indiana University CE Francisco Airport, [email protected] HOST: IU School of Optometry 1333 Old Bayshore Hwy 205-934-5701 CE HOURS: 16 CONTACT: Johanna Lieblein www.uab.edu/optometry/ce

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IN VISION CARE OCTOBER 6-8, 2016 2016 PHILADELPHIA MARRIOTT DOWNTOWN 1201 Market St, Philadelphia, PA 19107 REGISTER NOW! www.ReviewofOptometry.com/Philadelphia2016i fO /Phildl Or Email Lois DiDomenico: [email protected] | Call: 866-658-1772

Administered by Up to Review of Optometry® 19 CE Approval pending Credits (COPE approval pending)

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123

45678910 Tropical CE – Napa 2016 Envision Conference 2016 OEP Foundation The Art + Science of Optometric Care OEP Foundation VT/Strabismus + Amblyopia EyeFlyFish 2016 IU Alumni Weekend Vermont OA Fall Conference RSO Fall Seminar

11 12 13 14 15 16 17

OEP The Art + Science of Optometric Care Vision Expo West OEP VT/Strabismus + CE in Italy – Copenhagen Amblyopia EyeFlyFish 2016 Vermont OA Fall Conference RSO Fall Seminar

18 19 20 21 22 23 24 CE in Italy – CE in Italy – Florence CE in Italy – Tuscany Copenhagen Idaho Optometric Physicians Annual Congress Wisconsin OA 2016 Convention & Annual Meeting Illinois OA Annual Convention PSS Forum on Optometry New Mexico OA Mid-Year Convention 2016 Kentucky OA Fall Conference CE Sarasota Eye CE in Austin 25 26 27 28 29 30

PSS Forum on Optometry OAOP Fall Conference (ends Oct. 1) Illinois OA Annual Convention GWCO Congress 2016 (ends Oct. 2) CE in Italy – Tuscany 2016 Kentucky OA Fall Conference WOA 2016 Meeting CE in Austin

50 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 5050 112/3/152/3/15 1:081:08 PMPM Sept. (date TBD), Glendale, AZ SEPT. 29-OCT. 2, PORTLAND AZ-AAO Chapter Fall Meeting 2016 HOST: American Academy of Optometry Arizona Chapter CE HOURS: TBD LOCATION: Midwestern University Arizona College of Optometry, 19555 N. 59th Ave. There’s Great CE Out West! CONTACT: Carla Engelke [email protected] t’s time to think about www.aaopt.org/azchapter Iheading out west. The Great Western Council Fall (date TBD), Houston of Optometry is gear- Benedict Professor in Practice ing up for its annual Management & Administration conference, which will HOST: University of Houston College be held Sept. 29-Oct. 2 of Optometry in Portland, OR, where KEY FACULTY: Sam Quintero 90 hours of continuing CE HOURS: 8 education will be of- LOCATION: Health and Biomedical fered. Optometrists will Sciences Building at the University of be able to earn up to 30 CE credits. Other course topics will include Houston, 4901 Calhoun Rd. “GWCO Congress 2016 will feature amblyopia, binocular vision, co-man- CONTACT: University of Houston an innovative educational program agement, contact lenses, cornea and College of Optometry focused on advanced procedures, conjunctival disease, diabetes, dry [email protected] cutting-edge technology and collab- eye, eyelid and adnexal disease, glau- 713-743-1900 orative healthcare. We are thrilled to coma, neuro-ophthalmic disorders, http://ce.opt.uh.edu bring optometrists, optometry stu- nutrition and the eye, pediatric eye dents and optometry staff together care, pharmacology, practice man- Fall (date TBD), Fort Worth, TX for this unique learning experience,” agement, retinal disorders, systemic CE in Fort Worth says GWCO president Mark Lee, OD. disease, technology and uveitis. HOST: University of Houston College You also won’t want to miss of Optometry Optometrists, allied ophthalmic GWCO’s exhibit hall marketplace KEY FACULTY: Suzanne Wickum professionals and optometry stu- featuring the latest in new technolo- CE HOURS: 16 dents are all welcome to the meet- LOCATION: TBD ing, which will be held at the Oregon gies and products. CONTACT: University of Houston Convention Center and will off er For more information or to regis- College of Optometry Continuing myriad courses, including a session ter, contact Tracy Oman at gwco@ Education on advanced ophthalmic procedures. gwco.org or go to www.gwco.org. [email protected] 713-743-1900 Sept. 7-10, Denver Sept. 8-11, Listowel, Ontario, Canada http://ce.opt.uh.edu Envision Conference 2016 VT/Strabismus + Amblyopia HOST: Envision University HOST: OEP Foundation Sept. 4-8, Napa, CA KEY FACULTY: Gary Asano, Rebecca KEY FACULTY: Robert A. Hohendorf Tropical CE – Napa 2016 Kammer, Kendall Krug, Olga Overbury, CE HOURS: 28 HOST: Tropical CE Ronald Cole, Donald Fletcher LOCATION: Listowel, Ontario, Canada KEY FACULTY: Blair Lonsberry, David CE HOURS: Total: 90, maximum per CONTACT: Karen Ruder Kading CE HOURS: 14 OD: 21 [email protected] LOCATION: Silverado Resort and Spa, LOCATION: Grand Hyatt Denver, 410-561-3791 1600 Atlas Peak Rd. 1750 Whelton St. www.oepf.org/oepf_calendar CONTACT: Stuart Autry CONTACT: Michael Epp AM BV VT [email protected] [email protected] 281-808-5763 326-440-1515 Sept. 8-11, Alexandria, PA www.tropicalce.com www.envisionconference.org EyeFlyFish 2016 CL DB NT RE NO VT HOST: Charles Griff en, Mark Boas CE HOURS: 6 EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders LOCATION: Edgewater Inn and AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Riverside Grill, AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision 7653 Edgewater Acres Circle BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease CONTACT: Charles Griff en CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology c.griff [email protected] CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis 610-647-6550 CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy www.eyefl yfi sh.com

REVIEW OF OPTOMETRY DECEMBER 15, 2015 51

000_1215_ceconference_final.indd 51 12/3/15 1:54 PM Everyone’s a Winner at Vision Expo West in Vegas SEPTEMBER 14-17, LAS VEGAS

ure, Las Vegas is known as an adult Splayground where visitors can hit the blackjack tables or soar over the crowd below on the Slotzilla Zip Line, but the city is also getting a reputation as a place for exceptional CE, as Vision Expo West will once again host many of the top clinicians in Las Vegas for 2016. The meeting, scheduled from Sept. 14-17 at the Sands Expo & Conven- tion Center, will off er 320 hours of CE credit. Optometrists can earn up to 10 hours per day of the meeting, or 40 hours total. Another new “In the upcoming year, we’re heavily focused on program for understanding and addressing the core issues that 2016 is Lightning keep eye care professionals up at night and delivering Rounds, which programs that are timely and relevant to today’s chal- will off er four lenges,” says Vision Expo conference advisory co-chair hours of continu- Mark Dunbar, OD. “Whether that’s learning how to ing education expand a specialty practice, improve customer service, credit in a learning or learn new and eff ective marketing techniques, Vision format that gives Expo education off ers something to every professional attendees the regardless of how long they’ve been in the industry.” opportunity to hear from multiple speakers in a speed- One new program not to be missed will be Crash dating-type setting. Speakers will rotate between two Courses, a new learning format that will cover a wide rooms and give a short review of the topic, allowing the range of clinical and medical topics in attendee to benefi t from the perspectives of multiple six short sessions (30 minutes each) experts within one class. The topics will cover glaucoma to allow for more opportunities for and anterior segment disease, and the presenters will learning throughout the day. These be optometrists Eric Schmidt, Kirk Smick, Charlie Ficco, sessions—which will off er Louise Sclafani and Douglas Devries. three hours of CE Also new for 2016 is a practice management program, credit—include: • “PTEye: Corcoran Coding College, and Vision Series, which will Retina provide a mix of clinical and medical-oriented topics 30-Min- held within a social environment. ute New courses for 2016 will be “Debt Management for Count- Young Professionals” and “How to Develop a Dry Eye down” Center.” The latter course will help attendees learn how • “Amniotic to develop a dry eye center that will benefi t the patient Membranes: Why, How as well as generate signifi cant revenue from exams, pro- and When?” cedures and sales of materials. • “Google Contact Lens and Some familiar favorites will also be back at Vision Other Future Technologies” Expo West, including the Global Contact Lens Forum, • “Is this Acanthamoeba?” which continues to develop as an informative “meeting • “My Mid-Life Crisis and the within a meeting” at International Vision Expo, provid- Ganglion Cell Complex” ing insight into timely issues you face as a contact lens • “The Top 2 Craziest Ocular practitioner. This year, a new format gives you access to Emergencies that Happened to thought leaders in the fi eld sharing their views on the College Students” future of contact lens practice. (continued on page 56)

52 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 52 12/3/15 1:51 PM Prostaglandin Aqueous humor analogues production work better is highest in at night1 the morning2

Classic beta blocker adjunctive therapy for the right patient at the right time3

The concomitant use of two topical beta-adrenergic blocking agents is not recommended4,5

Indications and Usage ISTALOL® (timolol maleate ophthalmic solution) is a non-selective beta-adrenergic receptor blocking agent indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Preservative-free TIMOPTIC® (timolol maleate ophthalmic solution) in OCUDOSE® (dispenser) is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. It may be used when a patient is sensitive to the preservative in TIMOPTIC (timolol maleate ophthalmic solution), benzalkonium chloride, or when use of a preservative-free topical medication is advisable. Important Safety Information for Istalol® and Timoptic® in Ocudose® • Both ISTALOL® (timolol maleate ophthalmic solution) and TIMOPTIC® (timolol maleate ophthalmic solution) in OCUDOSE® (dispenser) are contraindicated in patients with: bronchial asthma; a history of bronchial asthma; severe chronic obstructive pulmonary disease; sinus bradycardia; second or third degree atrioventricular block; overt cardiac failure; cardiogenic shock; hypersensitivity to any component of the product. • The same adverse reactions found with systemic administration of beta-adrenergic blocking agents may occur with topical administration. Severe respiratory reactions and cardiac reaction, including death due to bronchospasm in patients with asthma, and rarely death in association with cardiac failure, have been reported following systemic or ophthalmic administration of timolol maleate. • Patients with a history of atopy or severe anaphylactic reactions to a variety of allergens may be unresponsive to the usual doses of epinephrine used to treat anaphylactic reactions. • Timolol has been reported rarely to increase muscle weakness in some patients with myasthenia gravis or myasthenic symptoms. • Beta-adrenergic blocking agents may mask signs and symptoms of acute hypoglycemia or certain clinical signs of hyperthyroidism. Patients subject to spontaneous hypoglycemia, or diabetic patients receiving either insulin or oral hypoglycemic agents, or patients suspected of developing thyrotoxicosis, should be managed carefully, with caution. • In patients undergoing elective surgery, some authorities recommend gradual withdrawal of beta adrenergic receptor blocking agents because these agents impair the ability of the heart to respond to beta-adrenergically mediated reflex stimuli. • The most frequently reported adverse reactions have been burning and stinging upon instillation. This was seen in 38% of patients treated with ISTALOL and in approximately one in eight patients treated with TIMOPTIC in OCUDOSE. Additional reactions reported with ISTALOL at a frequency of 4 to 10% include: blurred vision, cataract, conjunctival injection, headache, hypertension, infection, itching and decreased visual acuity. Please see Brief Summary of Prescribing Information for ISTALOL and TIMOPTIC in OCUDOSE on the following pages.

For the patients who need incremental IOP For the patients who need incremental IOP reduction in a preservative free form6 reduction in a once a day form6

Preservative-Free

TIMOPTIC® in OCUDOSE® (TIMOLOL MALEATE 0.5% (DISPENSER) OPHTHALMIC SOLUTION)

References: 1. Alm A, Stjernschantz J. Effects on Intraocular Pressure and Side Effects of 0.005% Latanoprost Applied Once Daily, Evening or Morning. Ophthalmology. 1995;102:1743-1752. 2. Brubaker R. Flow of Aqueous Humor in Humans. IOVS. 1991;32:(13)3145-3166. 3. Obstbaum S, Cioffi GA, Krieglstein GK, et al. Gold Standard Medical Therapy for Glaucoma: Defining the Criteria Identifying Measures for an Evidence-Based Analysis. Clin Ther. 2004;26(12)2102-2119. 4. Istalol [package insert]. Bridgewater, NJ: Bausch & Lomb Incorporated; 2013. 5. Timoptic in Ocudose [package insert]. Lawrenceville, NJ: Aton Pharma; 2009. 6. Stewart W, Day DG, Sharpe ED. Efficacy and Safety of Timolol Solution Once Daily vs Timolol Gel Added to Latanoprost. Am J Ophthalmol. 1999;128(6)692-696.

Timoptic and Ocudose are trademarks of Valeant Pharmaceuticals International, Inc. or its affiliates. Bausch + Lomb and Istalol are trademarks of Bausch & Lomb Incorporated or its affiliates.

©Bausch & Lomb Incorporated. US/TOP/14/0017(1)

RP1114_Valeant.indd 1 10/20/14 10:33 AM BRIEF SUMMARY OF PRESCRIBING INFORMATION atrioventricular block, or cardiac failure should be advised not to take this product. phenomenon, and cold hands and feet. This Brief Summary does not include all the information needed to use TIMOPTIC® (See CONTRAINDICATIONS.) DIGESTIVE: Nausea, diarrhea, dyspepsia, anorexia, and dry mouth. 0.25% AND 0.5% (timolol maleate ophthalmic solution) in OCUDOSE® (DISPENSER) Drug Interactions: Although TIMOPTIC (timolol maleate ophthalmic solution) used IMMUNOLOGIC: Systemic lupus erythematosus. safely and effectively. See full prescribing information for TIMOPTIC in OCUDOSE. alone has little or no effect on pupil size, mydriasis resulting from concomitant therapy NERVOUS SYSTEM/PSYCHIATRIC: Dizziness, increase in signs and symptoms of PRESERVATIVE-FREE STERILE OPHTHALMIC SOLUTION with TIMOPTIC (timolol maleate ophthalmic solution) and epinephrine has been myasthenia gravis, paresthesia, somnolence, insomnia, nightmares, behavioral changes in a Sterile Ophthalmic Unit Dose Dispenser reported occasionally. and psychic disturbances including depression, confusion, hallucinations, anxiety, Beta-adrenergic blocking agents: Patients who are receiving a beta-adrenergic disorientation, nervousness, and memory loss. ® blocking agent orally and Preservative-free TIMOPTIC in OCUDOSE should be observed SKIN: Alopecia and psoriasiform rash or exacerbation of psoriasis. TIMOPTIC 0.25% AND 0.5% for potential additive effects of beta-blockade, both systemic and on intraocular HYPERSENSITIVITY: Signs and symptoms of systemic allergic reactions including (TIMOLOL MALEATE OPHTHALMIC SOLUTION) pressure. The concomitant use of two topical beta-adrenergic blocking agents is anaphylaxis, angioedema, urticaria, and localized and generalized rash. ® not recommended. RESPIRATORY: Bronchospasm (predominantly in patients with pre-existing in OCUDOSE (DISPENSER) Calcium antagonists: Caution should be used in the coadministration of beta- bronchospastic disease), respiratory failure, dyspnea, nasal congestion, cough and upper adrenergic blocking agents, such as Preservative-free TIMOPTIC in OCUDOSE, and oral respiratory infections. INDICATIONS AND USAGE or intravenous calcium antagonists, because of possible atrioventricular conduction ENDOCRINE: Masked symptoms of hypoglycemia in diabetic patients (see WARNINGS). Preservative-free TIMOPTIC in OCUDOSE is indicated in the treatment of elevated disturbances, left ventricular failure, and hypotension. In patients with impaired cardiac SPECIAL SENSES: Signs and symptoms of ocular irritation including conjunctivitis, intraocular pressure in patients with ocular hypertension or open-angle glaucoma. function, coadministration should be avoided. blepharitis, keratitis, ocular pain, discharge (e.g., crusting), foreign body sensation, Preservative-free TIMOPTIC in OCUDOSE may be used when a patient is sensitive Catecholamine-depleting drugs: Close observation of the patient is recommended itching and tearing, and dry eyes; ptosis; decreased corneal sensitivity; cystoid to the preservative in TIMOPTIC (timolol maleate ophthalmic solution), benzalkonium when a beta blocker is administered to patients receiving catecholamine-depleting macular edema; visual disturbances including refractive changes and diplopia; chloride, or when use of a preservative-free topical medication is advisable. drugs such as reserpine, because of possible additive effects and the production of pseudopemphigoid; choroidal detachment following filtration surgery (see PRECAUTIONS, hypotension and/or marked bradycardia, which may result in vertigo, syncope, or General); and tinnitus. CONTRAINDICATIONS postural hypotension. UROGENITAL: Retroperitoneal fibrosis, decreased libido, impotence, and Peyronie’s disease. Preservative-free TIMOPTIC in OCUDOSE is contraindicated in patients with (1) Digitalis and calcium antagonists: The concomitant use of beta-adrenergic blocking The following additional adverse effects have been reported in clinical experience bronchial asthma; (2) a history of bronchial asthma; (3) severe chronic obstructive agents with digitalis and calcium antagonists may have additive effects in prolonging with ORAL timolol maleate or other ORAL beta blocking agents, and may be considered pulmonary disease (see WARNINGS); (4) sinus bradycardia; (5) second or third degree atrioventricular conduction time. potential effects of ophthalmic timolol maleate: Allergic: Erythematous rash, fever atrioventricular block; (6) overt cardiac failure (see WARNINGS); (7) cardiogenic shock; or CYP2D6 inhibitors: Potentiated systemic beta-blockade (e.g., decreased heart rate, combined with aching and sore throat, laryngospasm with respiratory distress; Body (8) hypersensitivity to any component of this product. depression) has been reported during combined treatment with CYP2D6 inhibitors (e.g., as a Whole: Extremity pain, decreased exercise tolerance, weight loss; Cardiovascular: quinidine, SSRIs) and timolol. Worsening of arterial insufficiency, vasodilatation; Digestive: Gastrointestinal pain, WARNINGS Clonidine: Oral beta-adrenergic blocking agents may exacerbate the rebound hepatomegaly, vomiting, mesenteric arterial thrombosis, ischemic colitis; Hematologic: As with many topically applied ophthalmic drugs, this drug is absorbed systemically. hypertension which can follow the withdrawal of clonidine. There have been no reports of Nonthrombocytopenic purpura; thrombocytopenic purpura; agranulocytosis; Endocrine: The same adverse reactions found with systemic administration of exacerbation of rebound hypertension with ophthalmic timolol maleate. Hyperglycemia, hypoglycemia; Skin: Pruritus, skin irritation, increased pigmentation, beta-adrenergic blocking agents may occur with topical administration. For Injectable epinephrine: (See PRECAUTIONS, General, Anaphylaxis) sweating; Musculoskeletal: Arthralgia; Nervous System/Psychiatric: Vertigo, local example, severe respiratory reactions and cardiac reactions, including death weakness, diminished concentration, reversible mental depression progressing to due to bronchospasm in patients with asthma, and rarely death in association Carcinogenesis, Mutagenesis, Impairment of Fertility: In a two-year oral study of timolol maleate administered orally to rats, there was a statistically significant catatonia, an acute reversible syndrome characterized by disorientation for time and with cardiac failure, have been reported following systemic or ophthalmic place, emotional lability, slightly clouded sensorium, and decreased performance administration of timolol maleate (see CONTRAINDICATIONS). increase in the incidence of adrenal pheochromocytomas in male rats administered 300 mg/kg/day (approximately 42,000 times the systemic exposure following the on neuropsychometrics; Respiratory: Rales, bronchial obstruction; Urogenital: Cardiac Failure: Sympathetic stimulation may be essential for support of the circulation maximum recommended human ophthalmic dose). Similar differences were not Urination difficulties. in individuals with diminished myocardial contractility, and its inhibition by beta- observed in rats administered oral doses equivalent to approximately 14,000 times the adrenergic receptor blockade may precipitate more severe failure. OVERDOSAGE maximum recommended human ophthalmic dose. There have been reports of inadvertent overdosage with Ophthalmic Solution In Patients Without a History of Cardiac Failure continued depression of the In a lifetime oral study in mice, there were statistically significant increases in myocardium with beta-blocking agents over a period of time can, in some cases, lead to TIMOPTIC (timolol maleate ophthalmic solution) resulting in systemic effects similar the incidence of benign and malignant pulmonary tumors, benign uterine polyps and to those seen with systemic beta-adrenergic blocking agents such as dizziness, cardiac failure. At the first sign or symptom of cardiac failure, Preservative-free TIMOPTIC mammary adenocarcinomas in female mice at 500 mg/kg/day (approximately 71,000 in OCUDOSE should be discontinued. headache, shortness of breath, bradycardia, bronchospasm, and cardiac arrest (see times the systemic exposure following the maximum recommended human ophthalmic also ADVERSE REACTIONS). Obstructive Pulmonary Disease: Patients with chronic obstructive pulmonary disease dose), but not at 5 or 50 mg/kg/day (approximately 700 or 7,000 times, respectively, the (e.g., chronic bronchitis, emphysema) of mild or moderate severity, bronchospastic Overdosage has been reported with Tablets BLOCADREN* (timolol maleate tablets). A systemic exposure following the maximum recommended human ophthalmic dose). In 30 year old female ingested 650 mg of BLOCADREN (maximum recommended oral daily disease, or a history of bronchospastic disease (other than bronchial asthma or a subsequent study in female mice, in which post-mortem examinations were limited to a history of bronchial asthma, in which TIMOPTIC in OCUDOSE is contraindicated dose is 60 mg) and experienced second and third degree heart block. She recovered the uterus and the lungs, a statistically significant increase in the incidence of pulmonary without treatment but approximately two months later developed irregular heartbeat, [see CONTRAINDICATIONS]) should, in general, not receive beta-blockers, including tumors was again observed at 500 mg/kg/day. Preservativefree TIMOPTIC in OCUDOSE. hypertension, dizziness, tinnitus, faintness, increased pulse rate, and borderline first The increased occurrence of mammary adenocarcinomas was associated with degree heart block. Major Surgery: The necessity or desirability of withdrawal of beta-adrenergic blocking elevations in serum prolactin which occurred in female mice administered oral timolol An in vitro hemodialysis study, using 14C timolol added to human plasma or whole agents prior to major surgery is controversial. Beta-adrenergic receptor blockade impairs at 500 mg/kg/day, but not at doses of 5 or 50 mg/kg/day. An increased incidence blood, showed that timolol was readily dialyzed from these fluids; however, a study of the ability of the heart to respond to beta-adrenergically mediated reflex stimuli. This of mammary adenocarcinomas in rodents has been associated with administration patients with renal failure showed that timolol did not dialyze readily. may augment the risk of general anesthesia in surgical procedures. Some patients of several other therapeutic agents that elevate serum prolactin, but no correlation receiving beta-adrenergic receptor blocking agents have experienced protracted severe between serum prolactin levels and mammary tumors has been established in humans. DOSAGE AND ADMINISTRATION hypotension during anesthesia. Difficulty in restarting and maintaining the heartbeat has Furthermore, in adult human female subjects who received oral dosages of up to 60 mg Preservative-free TIMOPTIC in OCUDOSE is a sterile solution that does not contain also been reported. For these reasons, in patients undergoing elective surgery, some of timolol maleate (the maximum recommended human oral dosage), there were no a preservative. The solution from one individual unit is to be used immediately after authorities recommend gradual withdrawal of beta-adrenergic receptor blocking agents. clinically meaningful changes in serum prolactin. opening for administration to one or both eyes. Since sterility cannot be guaranteed after If necessary during surgery, the effects of beta-adrenergic blocking agents may be Timolol maleate was devoid of mutagenic potential when tested in vivo (mouse) in the individual unit is opened, the remaining contents should be discarded immediately reversed by sufficient doses of adrenergic agonists. the micronucleus test and cytogenetic assay (doses up to 800 mg/kg) and in vitro in after administration. Diabetes Mellitus: Beta-adrenergic blocking agents should be administered with a neoplastic cell transformation assay (up to 100 mcg/mL). In Ames tests the highest Preservative-free TIMOPTIC in OCUDOSE is available in concentrations of 0.25 and caution in patients subject to spontaneous hypoglycemia or to diabetic patients concentrations of timolol employed, 5,000 or 10,000 mcg/plate, were associated with 0.5 percent. The usual starting dose is one drop of 0.25 percent Preservative-free (especially those with labile diabetes) who are receiving insulin or oral hypoglycemic statistically significant elevations of revertants observed with tester strain TA100 (in TIMOPTIC in OCUDOSE in the affected eye(s) administered twice a day. Apply enough agents. Beta-adrenergic receptor blocking agents may mask the signs and symptoms seven replicate assays), but not in the remaining three strains. In the assays with tester gentle pressure on the individual container to obtain a single drop of solution. If the of acute hypoglycemia. strain TA100, no consistent dose response relationship was observed, and the ratio of clinical response is not adequate, the dosage may be changed to one drop of 0.5 percent Thyrotoxicosis: Beta-adrenergic blocking agents may mask certain clinical signs (e.g., test to control revertants did not reach 2. A ratio of 2 is usually considered the criterion solution in the affected eye(s) administered twice a day. tachycardia) of hyperthyroidism. Patients suspected of developing thyrotoxicosis should for a positive Ames test. Since in some patients the pressure-lowering response to Preservative-free be managed carefully to avoid abrupt withdrawal of beta-adrenergic blocking agents that Reproduction and fertility studies in rats demonstrated no adverse effect on male TIMOPTIC in OCUDOSE may require a few weeks to stabilize, evaluation should include might precipitate a thyroid storm. or female fertility at doses up to 21,000 times the systemic exposure following the a determination of intraocular pressure after approximately 4 weeks of treatment with maximum recommended human ophthalmic dose. Preservative-free TIMOPTIC in OCUDOSE. PRECAUTIONS Pregnancy: Teratogenic Effects — Pregnancy Category C. Teratogenicity studies with If the intraocular pressure is maintained at satisfactory levels, the dosage schedule General: Because of potential effects of beta-adrenergic blocking agents on blood timolol in mice, rats and rabbits at oral doses up to 50 mg/kg/day (7,000 times the may be changed to one drop once a day in the affected eye(s). Because of diurnal pressure and pulse, these agents should be used with caution in patients with systemic exposure following the maximum recommended human ophthalmic dose) variations in intraocular pressure, satisfactory response to the once-a-day dose is best cerebrovascular insufficiency. If signs or symptoms suggesting reduced cerebral blood demonstrated no evidence of fetal malformations. Although delayed fetal ossification was determined by measuring the intraocular pressure at different times during the day. flow develop following initiation of therapy with Preservative-free TIMOPTIC in OCUDOSE, observed at this dose in rats, there were no adverse effects on postnatal development Dosages above one drop of 0.5 percent TIMOPTIC (timolol maleate ophthalmic alternative therapy should be considered. of offspring. Doses of 1000 mg/kg/day (142,000 times the systemic exposure solution) twice a day generally have not been shown to produce further reduction in Choroidal detachment after filtration procedures has been reported with the following the maximum recommended human ophthalmic dose) were maternotoxic intraocular pressure. If the patient’s intraocular pressure is still not at a satisfactory administration of aqueous suppressant therapy (e.g. timolol). in mice and resulted in an increased number of fetal resorptions. Increased fetal level on this regimen, concomitant therapy with other agent(s) for lowering intraocular Angle-closure glaucoma: In patients with angle-closure glaucoma, the immediate resorptions were also seen in rabbits at doses of 14,000 times the systemic exposure pressure can be instituted taking into consideration that the preparation(s) used objective of treatment is to reopen the angle. This requires constricting the pupil. Timolol following the maximum recommended human ophthalmic dose, in this case without concomitantly may contain one or more preservatives. The concomitant use of two maleate has little or no effect on the pupil. TIMOPTIC in OCUDOSE should not be used apparent maternotoxicity. topical beta-adrenergic blocking agents is not recommended. (See PRECAUTIONS, Drug alone in the treatment of angle-closure glaucoma. There are no adequate and well-controlled studies in pregnant women. Preservative- Interactions, Beta-adrenergic blocking agents.) Anaphylaxis: While taking beta-blockers, patients with a history of atopy or a free TIMOPTIC in OCUDOSE should be used during pregnancy only if the potential benefit ------history of severe anaphylactic reactions to a variety of allergens may be more reactive justifies the potential risk to the fetus. to repeated accidental, diagnostic, or therapeutic challenge with such allergens. Nursing Mothers: Timolol maleate has been detected in human milk following oral and Such patients may be unresponsive to the usual doses of epinephrine used to treat ophthalmic drug administration. Because of the potential for serious adverse reactions anaphylactic reactions. from timolol in nursing infants, a decision should be made whether to discontinue Muscle Weakness: Beta-adrenergic blockade has been reported to potentiate muscle nursing or to discontinue the drug, taking into account the importance of the drug to weakness consistent with certain myasthenic symptoms (e.g., diplopia, ptosis, and the mother. generalized weakness). Timolol has been reported rarely to increase muscle weakness in Pediatric Use: Safety and effectiveness in pediatric patients have not been established. By: Laboratories Merck Sharp & Dohme-Chibret some patients with myasthenia gravis or myasthenic symptoms. 63963 Clermont-Ferrand Cedex 9, France Geriatric Use: No overall differences in safety or effectiveness have been observed Information for Patients: Patients should be instructed about the use of Preservative- between elderly and younger patients. free TIMOPTIC in OCUDOSE. Based on PI - 514266Z/069A-03/09/9689-9690 Since sterility cannot be maintained after the individual unit is opened, patients should ADVERSE REACTIONS US/TOP/14/0018 Issued February 2009 be instructed to use the product immediately after opening, and to discard the individual The most frequently reported adverse experiences have been burning and stinging unit and any remaining contents immediately after use. upon instillation (approximately one in eight patients). Patients with bronchial asthma, a history of bronchial asthma, severe chronic The following additional adverse experiences have been reported less frequently with obstructive pulmonary disease, sinus bradycardia, second or third degree ocular administration of this or other timolol maleate formulations: ------BODY AS A WHOLE: Headache, asthenia/fatigue, and chest pain. * Registered trademark of ATON PHARMA, INC. CARDIOVASCULAR: Bradycardia, arrhythmia, hypotension, hypertension, syncope, heart COPYRIGHT © 2009 ATON PHARMA, INC. block, cerebral vascular accident, cerebral ischemia, cardiac failure, worsening of angina All rights reserved pectoris, palpitation, cardiac arrest, pulmonary edema, edema, claudication, Raynaud’s

RP1114_Valeant Timpotic PI.indd 1 10/20/14 10:53 AM BRIEF SUMMARY OF PRESCRIBING INFORMATION symptoms suggesting reduced cerebral blood flow develop following initiation of in rats, there were no adverse effects on postnatal development of offspring. Doses This Brief Summary does not include all the information needed to therapy with Istalol, alternative therapy should be considered. of 1000 mg/kg/day (142,000 times the systemic exposure following the maximum use ISTALOL® (timolol maleate ophthalmic solution) 0.5% safely and 5.12 Choroidal Detachment: Choroidal detachment after filtration procedures recommended human ophthalmic dose) were maternotoxic in mice and resulted effectively. See full prescribing information for ISTALOL. has been reported with the administration of aqueous suppressant therapy (e.g. in an increased number of fetal resorptions. Increased fetal resorptions were also timolol). seen in rabbits at doses of 14,000 times the systemic exposure following the ® (timolol maleate ophthalmic solution) 0.5% ADVERSE REACTIONS maximum recommended human ophthalmic dose, in this case without apparent Istalol maternotoxicity. There are no adequate and well-controlled studies in pregnant Initial U.S. Approval: 1978 6.1 Clinical Trials Experience: Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a women. Istalol should be used during pregnancy only if the potential benefit justifies STERILE drug cannot be directly compared to rates in the clinical trials of another drug and the potential risk to the fetus. INDICATIONS AND USAGE may not reflect the rates observed in practice. 8.3 Nursing Mothers: Timolol has been detected in human milk following oral Istalol (timolol maleate ophthalmic solution) 0.5% is a non-selective beta-adrenergic The most frequently reported adverse reactions have been burning and stinging and ophthalmic drug administration. Because of the potential for serious adverse receptor blocking agent indicated in the treatment of elevated intraocular pressure upon instillation in 38% of patients treated with Istalol. Additional reactions reported reactions from Istalol in nursing infants, a decision should be made whether to (IOP) in patients with ocular hypertension or open-angle glaucoma. with Istalol at a frequency of 4 to 10% include: blurred vision, cataract, conjunctival discontinue nursing or to discontinue the drug, taking into account the importance CONTRAINDICATIONS injection, headache, hypertension, infection, itching and decreased visual acuity. of the drug to the mother. 4.1 Asthma, COPD: Istalol is contraindicated in patients with bronchial asthma; The following additional adverse reactions have been reported less frequently with 8.4 Pediatric Use: Safety and effectiveness in pediatric patients have not been a history of bronchial asthma; severe chronic obstructive pulmonary disease (see ocular administration of this or other timolol maleate formulations. established. WARNINGS AND PRECAUTIONS, 5.1, 5.3). Timolol (Ocular Administration): Body as a whole: Asthenia/fatigue and chest 8.5 Geriatric Use: No overall differences in safety or effectiveness have been 4.2 Sinus Bradycardia, AV Block, Cardiac Failure, Cardiogenic Shock: pain; Cardiovascular: Bradycardia, arrhythmia, hypotension, syncope, heart observed between elderly and younger patients. Istalol is contraindicated in patients with sinus bradycardia; second block, cerebral vascular accident, cerebral ischemia, cardiac failure, worsening OVERDOSAGE or third degree atrioventricular block; overt cardiac failure (see of angina pectoris, palpitation, cardiac arrest, pulmonary edema, edema, There have been reports of inadvertent overdosage with Istalol resulting in systemic WARNINGS AND PRECAUTIONS, 5.2); cardiogenic shock. claudication, Raynaud’s phenomenon and cold hands and feet; Digestive: Nausea, effects similar to those seen with systemic beta-adrenergic blocking agents such as 4.3 Hypersensitivity Reactions: Istalol is contraindicated in patients who have diarrhea, dyspepsia, anorexia, and dry mouth; Immunologic: Systemic lupus dizziness, headache, shortness of breath, bradycardia, bronchospasm, and cardiac exhibited a hypersensitivity reaction to any component of this product in the past. erythematosus; Nervous System/Psychiatric: Dizziness, increase in signs and arrest. An in vitro hemodialysis study, using 14C timolol added to human plasma or WARNINGS AND PRECAUTIONS symptoms of myasthenia gravis, paresthesia, somnolence, insomnia, nightmares, whole blood, showed that timolol was readily dialyzed from these fluids; however, 5.1 Potentiation of Respiratory Reactions Including Asthma: Istalol behavioral changes and psychic disturbances including depression, confusion, a study of patients with renal failure showed that timolol did not dialyze readily. contains timolol maleate; and although administered topically, it can be absorbed hallucinations, anxiety, disorientation, nervousness and memory loss; Skin: NONCLINICAL TOXICOLOGY systemically. Therefore, the same adverse reactions found with systemic Alopecia and psoriasiform rash or exacerbation of psoriasis; Hypersensitivity: Signs 13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility: In a two-year administration of beta-adrenergic blocking agents may occur with topical and symptoms of systemic allergic reactions, including angioedema, urticaria, study of timolol maleate administered orally to rats, there was a statistically administration. For example, severe respiratory reactions and cardiac reactions and localized and generalized rash; Respiratory: Bronchospasm (predominantly significant increase in the incidence of adrenal pheochromocytomas in male rats including death due to bronchospasm in patients with asthma, and rarely death in patients with pre-existing bronchospastic disease), respiratory failure, administered 300 mg/kg/day (approximately 42,000 times the systemic exposure in association with cardiac failure, have been reported following systemic or dyspnea, nasal congestion, cough and upper respiratory infections; Endocrine: following the maximum recommended human ophthalmic dose). Similar differences ophthalmic administration of timolol maleate (see CONTRAINDICATIONS, 4.1). Masked symptoms of hypoglycemia in diabetic patients (see WARNINGS AND were not observed in rats administered oral doses equivalent to approximately PRECAUTIONS, 5.6); Special Senses: Signs and symptoms of ocular irritation 5.2 Cardiac Failure: Sympathetic stimulation may be essential for support 14,000 times the maximum recommended human ophthalmic dose. In a lifetime including conjunctivitis, blepharitis, keratitis, ocular pain, discharge (e.g., crusting), of the circulation in individuals with diminished myocardial contractility, and its oral study in mice, there were statistically significant increases in the incidence foreign body sensation, itching and tearing, and dry eyes; ptosis, decreased corneal inhibition of beta-adrenergic receptor blockade may precipitate more severe failure. of benign and malignant pulmonary tumors, benign uterine polyps and mammary sensitivity; cystoid macular edema; visual disturbances including refractive changes In patients without a history of cardiac failure, continued depression of the adenocarcinomas in female mice at 500 mg/kg/day, (approximately 71,000 times and diplopia; pseudopemphigoid; choroidal detachment following filtration surgery myocardium with beta-blocking agents over a period of time can, in some cases, the systemic exposure following the maximum recommended human ophthalmic (see WARNINGS AND PRECAUTIONS, 5.12); Urogenital: Retroperitoneal fibrosis, lead to cardiac failure. At the first sign or symptom of cardiac failure, Istalol should dose), but not at 5 or 50 mg/kg/day (approximately 700 or 7,000, respectively, decreased libido, impotence, and Peyronie’s disease. be discontinued (see also CONTRAINDICATIONS, 4.2). times the systemic exposure following the maximum recommended human 5.3 Obstructive Pulmonary Disease: Patients with chronic obstructive 6.2 Postmarketing Experience ophthalmic dose). In a subsequent study in female mice, in which post-mortem pulmonary disease (e.g., chronic bronchitis, emphysema) of mild or moderate Oral Timolol/Oral Beta-blockers: The following additional adverse effects have examinations were limited to the uterus and the lungs, a statistically significant severity, bronchospastic disease, or a history of bronchospastic disease [other than been reported in clinical experience with ORAL timolol maleate or other ORAL beta- increase in the incidence of pulmonary tumors was again observed at 500 mg/ bronchial asthma or a history of bronchial asthma in which Istalol is contraindicated blocking agents and may be considered potential effects of ophthalmic timolol kg/day. The increased occurrence of mammary adenocarcinomas was associated (see CONTRAINDICATIONS, 4.2)] should, in general, not receive beta-blocking maleate: Allergic: Erythematous rash, fever combined with aching and sore throat, with elevations in serum prolactin which occurred in female mice administered oral agents, including Istalol. laryngospasm with respiratory distress; Body as a Whole: Extremity pain, decreased timolol at 500 mg/kg/day, but not at doses of 5 or 50 mg/kg/day. An increased incidence of mammary adenocarcinomas in rodents has been associated with 5.4 Increased Reactivity to Allergens: While taking beta-blockers, patients exercise tolerance, weight loss; Cardiovascular: Worsening of arterial insufficiency, administration of several other therapeutic agents that elevate serum prolactin, with a history of atopy or a history of severe anaphylactic reactions to a variety of vasodilatation; Digestive: Gastrointestinal pain, hepatomegaly, vomiting, mesenteric but no correlation between serum prolactin levels and mammary tumors has been allergens may be more reactive to repeated accidental, diagnostic, or therapeutic arterial thrombosis, ischemic colitis; Hematologic: Nonthrombocytopenic established in humans. Furthermore, in adult human female subjects who received challenge with such allergens. Such patients may be unresponsive to the usual purpura; thrombocytopenic purpura, agranulocytosis; Endocrine: Hyperglycemia, oral dosages of up to 60 mg of timolol maleate (the maximum recommended doses of epinephrine used to treat anaphylactic reactions. hypoglycemia; Skin: Pruritus, skin irritation, increased pigmentation, sweating; Musculoskeletal: Arthralgia; Nervous System/Psychiatric: Vertigo, local weakness, human oral dosage), there were no clinically meaningful changes in serum prolactin. 5.5 Potentiation of Muscle Weakness: Beta-adrenergic blockade has been diminished concentration, reversible mental depression progressing to catatonia, Timolol maleate was devoid of mutagenic potential when tested in vivo (mouse) reported to potentiate muscle weakness consistent with certain myasthenic an acute reversible syndrome characterized by disorientation for time and place, in the micronucleus test and cytogenetic assay (doses up to 800 mg/kg) and in symptoms (e.g., diplopia, ptosis, and generalized weakness). Timolol has been emotional lability, slightly clouded sensorium and decreased performance on vitro in a neoplastic cell transformation assay (up to 100 mcg/mL). In Ames tests reported rarely to increase muscle weakness in some patients with myasthenia neuropsychometrics; Respiratory: Rales, bronchial obstruction; Urogenital: Urination the highest concentrations of timolol employed, 5,000 or 10,000 mcg/plate, were gravis or myasthenic symptoms. difficulties. associated with statistically significant elevations of revertants observed with tester 5.6 Masking of Hypoglycemic Symptoms in Patients with Diabetes strain TA100 (in seven replicate assays), but not in the remaining three strains. In Mellitus: Beta-adrenergic blocking agents should be administered with caution DRUG INTERACTIONS 7.1 Beta-Adrenergic Blocking Agents: Patients who are receiving a beta- the assays with tester strain TA100, no consistent dose response relationship was in patients subject to spontaneous hypoglycemia or to diabetic patients (especially ® observed, and the ratio of test to control revertants did not reach 2. A ratio of 2 is those with labile diabetes) who are receiving insulin or oral hypoglycemic agents. adrenergic blocking agent orally and Istalol should be observed for potential additive effects of beta-blockade, both systemic and on intraocular pressure. usually considered the criterion for a positive Ames test. Reproduction and fertility Beta-adrenergic receptor blocking agents may mask the signs and symptoms of studies in rats demonstrated no adverse effect on male or female fertility at doses acute hypoglycemia. The concomitant use of two topical beta-adrenergic blocking agents is not recommended. up to 21,000 times the systemic exposure following the maximum recommended 5.7 Masking of Thyrotoxicosis: Beta-adrenergic blocking agents may mask human ophthalmic dose. certain clinical signs (e.g., tachycardia) of hyperthyroidism. Patients suspected of 7.2 Calcium Antagonists: Caution should be used in the co-administration of beta-adrenergic blocking agents, such as Istalol, and oral or intravenous calcium PATIENT COUNSELING INFORMATION developing thyrotoxicosis should be managed carefully to avoid abrupt withdrawal Patients with bronchial asthma, a history of bronchial asthma, severe chronic of beta-adrenergic blocking agents that might precipitate a thyroid storm. antagonists because of possible atrioventricular conduction disturbances, left ventricular failure, and hypotension. In patients with impaired cardiac function, co- obstructive pulmonary disease, sinus bradycardia, second or third degree 5.8 Contamination of Topical Ophthalmic Products After Use: There administration should be avoided. atrioventricular block, or cardiac failure should be advised not to take this product. have been reports of bacterial keratitis associated with the use of multiple-dose 7.3 Catecholamine-Depleting Drugs: Close observation of the patient (see CONTRAINDICATIONS, 4.1, 4.2) Patients should also be instructed that ocular containers of topical ophthalmic products. These containers had been inadvertently solutions, if handled improperly or if the tip of the dispensing container contacts contaminated by patients who, in most cases, had a concurrent corneal disease is recommended when a beta blocker is administered to patients receiving catecholamine-depleting drugs such as reserpine, because of possible additive the eye or surrounding structures, can become contaminated by common bacteria or a disruption of the ocular epithelial surface (see PATIENT COUNSELING known to cause ocular infections. Serious damage to the eye and subsequent INFORMATION, 17). effects and the production of hypotension and/or marked bradycardia, which may result in vertigo, syncope, or postural hypotension. loss of vision may result from using contaminated solutions. (see WARNINGS 5.9 Impairment of Beta-adrenergically Mediated Reflexes During Surgery: 7.4 Digitalis and Calcium Antagonists: The concomitant use of beta- AND PRECAUTIONS 5.8) Patients should also be advised that if they have ocular The necessity or desirability of withdrawal of beta-adrenergic blocking agents prior surgery or develop an intercurrent ocular condition (e.g., trauma or infection), they to major surgery is controversial. Beta-adrenergic receptor blockade impairs the adrenergic blocking agents with digitalis and calcium antagonists may have additive effects in prolonging atrioventricular conduction time. should immediately seek their physician’s advice concerning the continued use of ability of the heart to respond to beta-adrenergically mediated reflex stimuli. This the present multidose container. If more than one topical ophthalmic drug is being may augment the risk of general anesthesia in surgical procedures. Some patients 7.5 CYP2D6 Inhibitors: Potentiated systemic beta-blockade (e.g., decreased heart rate) has been reported during combined treatment with CYP2D6 inhibitors used, the drugs should be administered at least five minutes apart. Patients should receiving beta-adrenergic receptor blocking agents have experienced protracted ® (e.g., quinidine) and timolol. be advised that Istalol contains benzalkonium chloride which may be absorbed by severe hypotension during anesthesia. Difficulty in restarting and maintaining the soft contact lenses. Contact lenses should be removed prior to administration of 7.6 Clonidine: Oral beta-adrenergic blocking agents may exacerbate the heartbeat has also been reported. For these reasons, in patients undergoing elective the solution. Lenses may be reinserted 15 minutes following Istalol® administration. rebound hypertension which can follow the withdrawal of clonidine. There have surgery, some authorities recommend gradual withdrawal of beta-adrenergic Rx Only receptor blocking agents. If necessary during surgery, the effects of beta-adrenergic been no reports of exacerbation of rebound hypertension with ophthalmic timolol Manufactured by: blocking agents may be reversed by sufficient doses of adrenergic agonists. maleate. USE IN SPECIFIC POPULATIONS Bausch & Lomb Incorporated 5.10 Angle-Closure Glaucoma: In patients with angle-closure glaucoma, Tampa, FL 33637 the immediate objective of treatment is to reopen the angle. This may require 8.1 Pregnancy Under License from: constricting the pupil. Timolol maleate has little or no effect on the pupil. Istalol Teratogenic Effects: Pregnancy Category C: Teratogenicity studies have been SENJU Pharmaceutical Co., Ltd should not be used alone in the treatment of angle-closure glaucoma. performed in animals. Teratogenicity studies with timolol in mice, rats, and rabbits Osaka, Japan 541-0046 5.11 Cerebrovascular Insufficiency: Because of potential effects of beta- at oral doses up to 50 mg/kg/day (7,000 times the systemic exposure following the ®/TM are trademarks of Bausch & Lomb Incorporated or its affiliates. adrenergic blocking agents on blood pressure and pulse, these agents should maximum recommended human ophthalmic dose) demonstrated no evidence of © Bausch & Lomb Incorporated be used with caution in patients with cerebrovascular insufficiency. If signs or fetal malformations. Although delayed fetal ossification was observed at this dose Based on 9401500 US/IST/14/0007 Issued 06/2013

RRP1114_ValeantP1114_Valeant IstalolIstalol PI.inddPI.indd 1 110/20/140/20/14 11:0211:02 AMAM If you’re ready for a food challenge, try the eight-pound burger at The Pub inside the Monte Carlo Resort (www. montecarlo.com). Finish The Pub Challenge in 30 minutes and it’s free— and you get a free T-shirt. Piled high with vegetables and topped with a gi- ant bun, it won’t be easy to fi nish, but if you do, your name will go down in the Monte Carlo history books forever.

Table Stakes: Dining in Vegas Skip the shrimp at the all-night buff et table and try some of Vegas’ fi ne- dining hotspots, courtesy of Yelp: (continued from page 52) with the Voodoo Zipline. If that’s • Bouchon Bistro Lectures will emphasize clinical/sci- not enough, try the new Slotzilla 3355 S. Las Vegas Blvd. entifi c advancements as well as criti- Zipline right through the heart of the www.venetian.com/restaurants/ cal business strategies. Don’t miss a Fremont Street Experience (http:// french/bouchon.html new session dedicated to contact lens vegasexperience.com). • Carson Kitchen wear from your patient’s perspective. And just because you’re tall 124 S. 6th St. For more information or to register, enough to ride a coaster doesn’t www.carsonkitchen.com contact Leigh Mann at lmann@reed- mean you can handle just any roller • Sage, 3730 S. Las Vegas Blvd. expo.com, or go to www.visionex- coaster. Head down to Buff alo Bill’s http://aria.com/dining/restaurants powest.com. in Primm (www.primmvalleyresorts. • Gordon Ramsay Steak com) and see how you hold up 3655 S. Las Vegas Blvd. Vegas on the Edge against the Desperado’s Turbo Drop, www.caesars.com/paris-las-vegas (source: www.lasvegas.com) a 255-foot nosedive that highlights • Mon Ami Gabi Anyone over a certain height can ride one of the world’s tallest and fastest 3655 S. Las Vegas Blvd. a roller coaster, but it takes real guts scream machines. Or twist, loop www.monamigabi.com to swim with the sharks in the Shark and dive around New York City • Mesa Grill Reef Aquarium at Mandalay Bay with the Coney Island-style coaster 570 S. Las Vegas Blvd. (www.mandalaybay.com). There are at New York-New York (www. http://mesagrill.com no cages—just you, 1.3 million gallons newyorknewyork.com). • Gordon Ramsay BurGR of underwater real estate and more You also won’t want to miss Sky- 3667 S. Las Vegas Blvd. than 30 sharks, including sand tiger, Jump at the Stratosphere (www. www.gordonramsayrestaurants. sandbar and whitetip reef sharks. stratospherehotel.com). At 108 sto- com/burgr/ For some zip lining, head ries, it’s the highest controlled free fall • The Barrymore out to Boulder City for Bootleg in the world. At the top of the tower, 99 Convention Center Dr. Canyon Flightlines (www.lasvegas. you’ll also fi nd the X-Scream and www.barrymorelv.com com/listing/fl ightlinez-bootleg- Insanity waiting. • Giada, 3595 S. Las Vegas Blvd. canyon/19299/tour/1706). Soon, you’ll If you like speed, the Richard Petty www.thecromwell.com/giada be able to go from one hotel tower Rookie Driving Experience at Las • Oyster Bar to another at the Rio (https://www. Vegas Motor Speedway (www.lvms. 2411 W. Sahara Ave. caesars.com/rio-las-vegas/things- com) is your chance to race like a http://palacestation.sclv.com/ to-do/voodoo-zipline#.Vik4PGSrT-Y) NASCAR pro. dining/the-oyster-bar.aspx

Sept. 8-12, Timonium, MD CE HOURS: 16 CONTACT: Rebecca Hogan The Art + Science of Optometric Care LOCATION: IU School of Optometry, [email protected] HOST: OEP Foundation 800 E. Atwater, Room 105 vtoptometrists.org KEY FACULTY: John Abbondanza CONTACT: Cheryl Oldfi eld CE HOURS: 35 coldfi [email protected] Sept. 10-11, San Antonio, TX LOCATION: OEP National Education 812-856-3502 RSO Fall Seminar Center, 2300 York Rd., Suite 113 www.opt.indiana.edu/ce/seminars.htm HOST: Rosenberg School of CONTACT: Karen Ruder; 410-561-3791 Optometry [email protected] Sept. 9-11, Stowe, VT CE HOURS: 16 www.oepf.org/oepf_calendar Fall Conference LOCATION Rosenberg School of BV DS VT HOST: Vermont Optometric Optometry, 9725 Datapoint Association CONTACT: Sandra Fortenberry Sept. 9-10 (tentative), Bloomington, IN CE HOURS: 17 [email protected]; 210-283-6856 Alumni Weekend LOCATION: Topnotch Resort, 4000 www.uiw.edu/optometry/continuing- HOST: IU School of Optometry Mountain Rd. education

56 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 56 12/3/15 1:13 PM Sept. 14-17, Las Vegas CONTACT: Joleen Breunig [email protected] Vision Expo West [email protected] 203-415-3087 HOST: International Vision Expo & 608-824-2200 www.psseyecare.com Conference www.woa-eyes.org AL AM CM CL CD CS DB DE EL GL LT CE HOURS: Total: 320, maximum per GL RE SD NO NT IN PH PM RE RS SD TE VT OD: 40 LOCATION: Sands Expo & Convention Sept. 22-26, Springfi eld, IL Sept. 24, Sarasota, FL Center, 201 Sands Ave. IOA Annual Convention CE Sarasota Eye Symposium CONTACT: Leigh Mann HOST: Illinois Optometric Association HOST: CE Sarasota [email protected] CE HOURS: 15, 10 hours of TQ courses KEY FACULTY: Ron Melton, 203-840-5452 LOCATION: Crowne Plaza Hotel, Randall Thomas www.visionexpowest.com 3000 Dirksen Parkway CE HOURS: 9 AL AM BV CM CL CD CS DB DE EL GL CONTACT: Charlene Marsh LOCATION: Ritz-Carlton Sarasota LT NO NT IN DS PE PH PM RE RS SV [email protected] 111 Ritz Carlton Drive SD TE UV VT 217-525-8012 www.ioaweb.org CONTACT: Julie Peirce Sept. 16-18, Copenhagen, Denmark [email protected] CE in Italy Sept. 23-24, Mescalero, NM 941-993-8995 HOST: James Fanelli New Mexico Optometric Association CD CS DE GL IN PH RE RS KEY FACULTY: James Fanelli, Leonard Mid-Year Convention Messner, Lorraine Lombardi HOST: New Mexico Optometric Sept. 24-25, Austin, TX CE HOURS: 12 Association CE in Austin LOCATION: First Hotel Kong Frederik CE HOURS: 8 HOST: University of Houston College CONTACT: James Fanelli LOCATION: Inn of the Mountain Gods, of Optometry [email protected] 287 Carrizo Canyon Rd. KEY FACULTY: Pat Segu 910-452-7225 CONTACT: Richard Montoya CE HOURS: 16 www.ceinitaly.com [email protected] LOCATION: Omni Austin Hotel at CM DB GL LT NO RE SD 575-751-7242 Downtown, 700 San Jacinto at 8th St. www.newmexicooptometry.org CONTACT: University of Houston Sept. 20-22, Florence, Italy College of Optometry Continuing CE in Italy Sept. 23-25, Louisville, KY Education HOST: James Fanelli 2016 KOA Fall Conference [email protected] KEY FACULTY: James Fanelli, Leonard HOST: Kentucky Optometric 713-743-1900 Messner, Lorraine Lombardi Association CE HOURS: 12 CE HOURS: 20 http://ce.opt.uh.edu LOCATION: Hotel Silla LOCATION: Marriott Louisville East CONTACT: James Fanelli Hotel, 1903 Embassy Square Blvd. Sept. 29-Oct. 1, Tulsa, OK [email protected] CONTACT: Sarah Unger OAOP Fall Conference 910-452-7225 [email protected] HOST: Oklahoma Association of www.ceinitaly.com 502-875-3516 Optometric Physicians CM CS DB EL GL NO IN PH RE SD UV www.kyeyes.org CE HOURS: TBD LOCATION: Renaissance Tulsa Hotel & Sept. 22-24, Boise, ID Sept. 23-25, Tuscany, Italy Convention Center, Idaho Optometric Physicians Annual CE in Italy 6808 S. 107th E. Ave. Congress HOST: James Fanelli CONTACT: Heatherlyn Burton HOST: Idaho Optometric Physicians KEY FACULTY: James Fanelli, [email protected] CE HOURS: 32 Leonard Messner, Lorraine Lombardi 405-524-1075 LOCATION: Boise Centre, CE HOURS: 12 www.oaop.org 850 W. Front St. LOCATION: Residence Le Santucce, CONTACT: Randy Andregg Castiglion Fiorentino Sept. 29-Oct. 2, Portland, OR [email protected] CONTACT: James Fanelli GWCO Congress 2016 208-461-0001 [email protected] HOST: Great Western Council of Idaho.aoa.org 910-452-7225 Optometry AL AM BV CM CT DB DE EL GL NO NT www.ceinitaly.com CE HOURS: Total: 90, Maximum per IN DS PM RE SD TE CM CS GL LT NO IN RE SD UV OD: 30 Sept. 22-25, Madison, WI Sept. 23-28, Mystic, CT LOCATION: Oregon Convention 2016 Convention & Annual Meeting Forum on Optometry Center, 777 NE MLK Jr. Blvd. HOST: Wisconsin Optometric HOST: PSS EyeCare CONTACT: Tracy Oman Association KEY FACULTY: Mile Brujic, Deepak [email protected] CE HOURS: Total: 26, maximum per Gupta, Joseph Sowka, Paul Ajamian 503-654-1062 OD: 22 CE HOURS: 18 www.gwco.org LOCATION: Madison Marriott West LOCATION: 625 North Road, Groton AM BV CM CL CD DB DE EL GL NO NT Hotel, 1313 John Q Hammons Dr. CONTACT: Sonia Kumari IN PE PH PM RE SD TE UV

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0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 5757 112/3/152/3/15 1:141:14 PMPM October

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

1 OAOP Fall Conference (begins Sep. 29) GWCO Congress 2016 (begins Sep. 29) Everything Therapeutic – San Antonio 2016 Imperial Japan CE

2345678 2016 Imperial Japan CE GWCO Congress 2016 OEP Foundation VT/Learning Related Visual Problems Everything Indiana Optometry’s Fall Seminar Therapeutic – San Antonio UAB Evening of 2016 Kansas Optometric Association Education Fall Eyecare Conference EastWest Eye Conference New Technologies and Treatments in Vision Care – Philadelphia PSS Forum on Ocular Disease 9101112131415 PSS Forum on Ocular Disease OEP VT/Learning Michigan OA Annual Fall Seminar Visual Problems 2016 Missouri Optometric Association Annual Convention 2016 Kansas OA Fall Eyecare Virginia OA Fall Conference Conference Georgia OA Fall Education Conference 2016 Imperial Neuro-Motor Maturity, Japan CE Optimizing Vision Therapy

16 17 18 19 20 21 22 2016 Missouri OA Connecticut Annual Convention Association of Optometrists Virginia OA Fall Annual Conference Conference Georgia OA Fall Education Conference Neuro-Motor Maturity, Optimizing Vision Therapy

23 24 25 26 27 28 29 Connecticut Association of Optometrists Annual Conference

30 31

58 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 5858 112/3/152/3/15 1:141:14 PMPM Oct. 1-2, San Antonio, TX Everything Therapeutic: San Antonio HOST: University of Houston College of Optometry KEY FACULTY: Bruce Onofrey CE HOURS: 16 LOCATION: Westin Riverwalk Hotel, 420 W Market St. OCT. 6-8, Earn CE Where East Meets West CLEVELAND CONTACT: University of Houston College of Optometry ark your calendar for the 19th to OD education, we off er a wide [email protected] Mannual EastWest Eye Confer- variety of patient-focused education 713-743-1900 ence 2016, to be held Oct. 6-8 in for staff .” http://ce.opt.uh.edu Cleveland. Housed along the shores In addition to a busy exhibit hall of Lake Erie in Cleveland’s state- and a daily dose of CE, expect to be Oct. 1-9, Tokyo, Hakone, Kyoto of-the-art Global Center for Health entertained at EastWest. 2016 Imperial Japan CE Innovation and Convention Center, “Cleveland is a great city that has HOST: iTravelCE EastWest off ers education from so many cultural off erings, includ- KEY FACULTY: Mile Brujic top-notch ODs including Ron Melton, ing the Rock and Roll Hall of Fame, CE HOURS: 18 Randall Thomas, Paul Karpecki, Mur- which EastWest takes over for a LOCATION: 6F Onarimon Yusen Bldg., ray Fingeret, Danica Marelli, David blowout party on the Friday night of 3-23-5 Nishi-Shinbashi, Minato-ku, Tokyo Kading, Bruce Onofrey and many the conference,” Dr. Quinn says. “We CONTACT: Bridgitte Shen Lee others. Two hundred hours of CE have many attendees bring family [email protected] credit will be available, and optom- and friends and make the event a 832-390-1393 etrists can earn up to 26 hours. weekend getaway.” www.itravelce.com “EastWest off ers such a wonderful Dr. Quinn encourages all to “come AL CM CL CD CS CT DE GL NT IN DS educational experience,” says confer- learn and have fun doing it!” PM RS TE ence chair Thomas Quinn, OD. “Edu- For more information, contact cation that makes a diff erence in Linda Fette at [email protected] or Oct. 5-6, Bloomington, IN patient care is our focus. In addition www.eastwesteye.org. Indiana Optometry’s Fall Seminar HOST: Indiana Optometric Association CE HOURS: 14 LOCATION: Indiana Memorial Union, 900 E. 7th St. CONTACT: Bridget Sims [email protected] 317-237-3560 www.ioa.org

Oct. 5-9, Phoenix VT/Learning Related Visual Problems LOCATION: UAB School of Center, 1 St. Clair Ave. HOST: OEP Foundation Optometry, 1716 University Blvd. CONTACT: Linda Fette KEY FACULTY: Rob Lewis CONTACT: Amanda Kachler [email protected] CE HOURS: 35 [email protected]; 205-934-5701 800-999-4939 LOCATION: TBD www.uab.edu/optometry/ce www.eastwesteye.org CONTACT: Karen Ruder AL AM BV CM CL CD CS CT DB DE EL [email protected] Oct. 6-8, Cleveland GL LT NO NT IN DS PE PH PM RE RS 410-561-3791 EastWest Eye Conference SV SD TE UV VT www.oepf.org/oepf_calendar HOST: Ohio Optometric Association AM BV VT KEY FACULTY: Randall Thomas, Oct. 6-8, Philadelphia Ron Melton, Murray Fingeret, Paul New Technologies and Treatments in Oct. 6, Birmingham, AL Karpecki, Bruce Onofrey Vision Care – Philadelphia Evening of Education CE HOURS: Total: 200+, Maximum HOST: Review of Optometry HOST: UAB School of Optometry per OD: 26 KEY FACULTY: Paul Karpecki CE HOURS: 2 LOCATION: Cleveland Convention (meeting chair) CE HOURS: 19 EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders LOCATION: Philadelphia Marriott AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery Downtown, 1201 Market St. AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision CONTACT: Lois DiDomenico BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease [email protected] CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology 866-658-1772 www.reviewofoptometry.com/ CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis philadelphia2016 CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy CM CL DB DE EL GL IN PH PE

REVIEW OF OPTOMETRY DECEMBER 15, 2015 59

000_1215_ceconference_final.indd 59 12/3/15 1:53 PM Oct. 6-13, Orlando CONTACT: Todd Fleischer LOCATION: Chateau on the Lake, Forum on Ocular Disease [email protected] 415 N. State Hwy 265 HOST: PSS EyeCare 785-232-0225 CONTACT: Lee Ann Barrett KEY FACULTY: Ron Melton, Randall www.kansasoptometric.org [email protected] Thomas, Mile Brujic, William Jones, 573-635-6151 Elliot Kirstein, Deepak Gupta Oct. 12-13, Lansing, MI www.moeyecare.org CE HOURS: 18 Michigan Optometric Association AL CD DB GL IN PH RE SD TE UV LOCATION: Swan and Dolphon Hotel, 48th Annual Fall Seminar 1500 Epcot Resorts Blvd. HOST: Michigan Optometric Oct. 14-16, Virginia Beach, VA CONTACT: Sonia Kumari Association VOA Fall Conference [email protected] CE HOURS: TBD HOST: Virginia Optometric 203-415-3087 LOCATION: Lansing Center, Association www.psseyecare.com 333 E. Michigan Ave. CE HOURS: 8 AL AM CM CL CD CS CT DB DE EL GL CONTACT: Amy Root LOCATION: Hilton Garden Inn, LT NO NT IN PH PM RE RS SD TE VT [email protected]; 517-482-0616 3315 Atlantic Ave. www.themoa.org CONTACT: Bo Keeney Oct. 7-9, Topeka, KS offi [email protected] 2016 Kansas Optometric Association Oct. 13-16, Branson, MO 804-643-0309 Fall Eyecare Conference 2016 MOA Annual Convention www.thevoa.org HOST: Kansas Optometric HOST: Missouri Optometric Association Association Oct. 14-16, Athens, GA CE HOURS: 13 KEY FACULTY: Blair Lonsberry, Georgia Optometric Association Fall LOCATION: DoubleTree by Hilton Nathan Lighthizer Education Conference Wichita Airport, 2098 Airport Rd. CE HOURS: 14 HOST: Georgia Optometric Association OCTOBER 6-8, CE HOURS: 18 PHILADELPHIA LOCATION: UGA Hotel and Conference Center, 1197 South Lumpkin St. CONTACT: Vanessa Grosso [email protected] 770-961-9866 x-1 Last Chance to see the ‘New Tech’ Series in 2016 www.GOAeyes.com GL NO IN PH PM SD on’t miss the fi nal New Technolo- Collegial and interactive, these Dgies and Treatments in Vision meetings customize education to Oct. 15-16, Burlington, Ontario, Care meeting slated for 2016! your needs. Philadelphia—always a Canada This series, hosted by Review of popular draw—hosts the last meeting Neuro-Motor Maturity, Optimizing Optometry, features nationally known of the year, at the Marriott Downtown, Vision Therapy Through Testing and experts like Paul Karpecki (pictured with 19 CE credit hours available. Integration Refl exes below) sharing their expertise at the For information and registration, HOST: Patricia Fink and OEP Fdn. podium, teaching hands-on proce- contact Lois DiDomenico at KEY FACULTY: Patti Andrich, Alex dures in workshops and engaging in [email protected] or Andrich direct one-on-one dialog with attend- check www.reviewofoptometry.com/ CE HOURS: 12 ees all throughout the event. philadelphia2016. LOCATION: 2080 Appleby Line, Ste. E6 CONTACT: Karen Ruder [email protected] 410-561-3791 www.oepf.org/oepf_calendar NO VT

Oct. 22-24, Groton, CT Annual Education Conference HOST: Connecticut Association of Optometrists CE HOURS: 18 LOCATION: Mystic Marriott Hotel & Spa, 625 North Rd. CONTACT: Stephanie Kopsak [email protected] 860-529-1900 www.cteyes.org

60 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 60 12/3/15 1:55 PM SELECTIVELY AND EFFECTIVELY TARGET VIRUS INFECTED CELLS

• Inactive in healthy corneal cells1 • Up to 77% of dendritic ulcers resolved at Day 72,3,*

* As demonstrated in a phase 3 open-label, randomized, controlled, multicenter clinical trial (N=164) in which patients with herpetic keratitis received either ZIRGAN® or acyclovir ophthalmic ointment 3%, administered 5 times daily until healing of ulcer and then 3 times daily for 1 week. Clinical resolution (healed ulcers) at day 7 was achieved in 77% (55/71) of patients treated with ZIRGAN® versus 72% (48/67) treated with acyclovir (diff erence, 5.8%; 95% CI, -9.6%-18.3%). ZIRGAN® was noninferior to acyclovir in patients with dendritic ulcers. Indication ZIRGAN® (ganciclovir ophthalmic gel) 0.15% is a topical ophthalmic antiviral that is indicated for the treatment of acute herpetic keratitis (dendritic ulcers). Important Safety Information about ZIRGAN® • ZIRGAN® is indicated for topical ophthalmic use only. • Patients should not wear contact lenses if they have signs or symptoms of herpetic keratitis or during the course of therapy with ZIRGAN®. • Most common adverse reactions reported in patients were blurred vision (60%), eye irritation (20%), punctate keratitis (5%), and conjunctival hyperemia (5%). • Safety and effi cacy in pediatric patients below the age of 2 years have not been established. Please see brief summary of Prescribing Information on the adjacent page.

References: 1. Foster CS. Ganciclovir gel—a new topical treatment for herpetic keratitis. US Ophthalmic Rev. 2008;3(1):52-56. 2. ZIRGAN Prescribing Information, April 2014. 3. Croxtall JD. Ganciclovir Ophthalmic Gel 0.15% in Acute Herpetic Keratitis (Dendritic Ulcers). Drugs. 2011;71(5):603-610.

Zirgan is a trademark of Laboratoires Théa Corporation used under license. © 2015 Bausch & Lomb Incorporated. All rights reserved. US/ZGN/15/0002

RO1015_BL Zirgan.indd 1 9/15/15 2:36 PM BRIEF SUMMARY OF PRESCRIBING INFORMATION is transformed by viral and cellular thymidine kinases (TK) to ganciclovir This Brief Summary does not include all the information needed to use Zirgan triphosphate, which works as an antiviral agent by inhibiting the synthesis of safely and effectively. See full prescribing information for Zirgan. viral DNA in 2 ways: competitive inhibition of viral DNA-polymerase and direct incorporation into viral primer strand DNA, resulting in DNA chain Zirgan ganciclovir ophthalmic gel 0.15% termination and prevention of replication. Initial U.S. Approval: 1989 12.3 Pharmacokinetics 1 INDICATIONS AND USAGE The estimated maximum daily dose of ganciclovir administered as ZIRGAN (ganciclovir ophthalmic gel) 0.15% is indicated for the treatment of 1 drop, 5 times per day is 0.375 mg. Compared to maintenance doses of acute herpetic keratitis (dendritic ulcers). systemically administered ganciclovir of 900 mg (oral valganciclovir) and 5 mg/kg (IV ganciclovir), the ophthalmically administered daily dose is 2 DOSAGE AND ADMINISTRATION approximately 0.04% and 0.1% of the oral dose and IV doses, respectively, The recommended dosing regimen for ZIRGAN is 1 drop in the affected eye thus minimal systemic exposure is expected. 5 times per day (approximately every 3 hours while awake) until the corneal 13 NONCLINICAL TOXICOLOGY ulcer heals, and then 1 drop 3 times per day for 7 days. 13.1 Carcinogenesis, Mutagenesis, and Impairment of Fertilty 3 DOSAGE FORMS AND STRENGTHS Ganciclovir was carcinogenic in the mouse at oral doses of ZIRGAN contains 0.15% of ganciclovir in a sterile preserved topical 20 and 1,000 mg/kg/day (approximately 3,000x and 160,000x the human ophthalmic gel. ocular dose of 6.25 mcg/kg/day, assuming complete absorption). At the 4 CONTRAINDICATIONS dose of 1,000 mg/kg/day there was a significant increase in the incidence of tumors of the preputial gland in males, forestomach (nonglandular None. mucosa) in males and females, and reproductive tissues (ovaries, uterus, 5 WARNINGS AND PRECAUTIONS mammary gland, clitoral gland, and vagina) and liver in females. At the dose of 20 mg/kg/day, a slightly increased incidence of tumors was noted 5.1 Topical Ophthalmic Use Only in the preputial and harderian glands in males, forestomach in males and ZIRGAN is indicated for topical ophthalmic use only. females, and liver in females. No carcinogenic effect was observed in mice administered ganciclovir at 1 mg/kg/day (160x the human ocular dose). 5.2 Avoidance of Contact Lenses Except for histocytic sarcoma of the liver, ganciclovir-induced tumors were Patients should not wear contact lenses if they have signs or symptoms of generally of epithelial or vascular origin. Although the preputial and clitoral herpetic keratitis or during the course of therapy with ZIRGAN. glands, forestomach and harderian glands of mice do not have human 6 ADVERSE REACTIONS counterparts, ganciclovir should be considered a potential carcinogen in Most common adverse reactions reported in patients were blurred vision humans. Ganciclovir increased mutations in mouse lymphoma cells and DNA (60%), eye irritation (20%), punctate keratitis damage in human lymphocytes in vitro at concentrations between 50 to 500 (5%), and conjunctival hyperemia (5%). and 250 to 2,000 mcg/mL, respectively. In the mouse micronucleus assay, ganciclovir was clastogenic at doses of 8 USE IN SPECIFIC POPULATIONS 150 and 500 mg/kg (IV) (24,000x to 80,000x human ocular dose) but not 50 mg/kg (8,000x human ocular dose). Ganciclovir was not mutagenic in 8.1 Pregnancy: Teratogenic Effects the Ames Salmonella assay at concentrations of 500 to 5,000 mcg/mL. Pregnancy Category C: Ganciclovir has been shown to be embryotoxic Ganciclovir caused decreased mating behavior, decreased fertility, and an in rabbits and mice following intravenous administration and teratogenic in increased incidence of embryolethality in female mice following intravenous rabbits. Fetal resorptions were present in at least 85% of rabbits and mice doses of 90 mg/kg/day (approximately 14,000x the human ocular dose of administered 60 mg/kg/day and 108 mg/kg/day (approximately 10,000x 6.25 mcg/kg/day). Ganciclovir caused decreased fertility in male mice and and 17,000x the human ocular dose of 6.25 mcg/kg/day), respectively, hypospermatogenesis in mice and dogs following daily oral or intravenous assuming complete absorption. Effects observed in rabbits included: fetal administration of doses ranging from 0.2 to 10 mg/kg (30x to 1,600x the growth retardation, embryolethality, teratogenicity, and/or maternal toxicity. human ocular dose). Teratogenic changes included cleft palate, anophthalmia/microphthalmia, aplastic organs (kidney and pancreas), hydrocephaly, and brachygnathia. 14 CLINICAL STUDIES In mice, effects observed were maternal/fetal toxicity and embryolethality. In one open-label, randomized, controlled, multicenter clinical trial which Daily intravenous doses of 90 mg/kg/day (14,000x the human ocular enrolled 164 patients with herpetic keratitis, ZIRGAN was non-inferior dose) administered to female mice prior to mating, during gestation, and to acyclovir ophthalmic ointment, 3% in patients with dendritic ulcers. during lactation caused hypoplasia of the testes and seminal vesicles in the Clinical resolution (healed ulcers) at Day 7 was achieved in 77% (55/71) for month-old male offspring, as well as pathologic changes in the nonglandular ZIRGAN versus 72% (48/67) for acyclovir 3% (difference 5.8%, 95% CI region of the stomach (see Carcinogenesis, Mutagenesis, and Impairment of - 9.6%-18.3%). In three randomized, single-masked, controlled, multicenter Fertility). clinical trials which enrolled 213 total patients, ZIRGAN was non-inferior to There are no adequate and well-controlled studies in pregnant women. acyclovir ophthalmic ointment 3% in patients with dendritic ulcers. Clinical ZIRGAN should be used during pregnancy only if the potential benefit resolution at Day 7 was achieved in 72% (41/57) for ZIRGAN versus 69% justifies the potential risk to the fetus. (34/49) for acyclovir (difference 2.5%, 95% CI - 15.6%-20.9%). 8.3 Nursing Mothers 17 PATIENT COUNSELING INFORMATION It is not known whether topical ophthalmic ganciclovir administration could This product is sterile when packaged. Patients should be advised not to allow result in sufficient systemic absorption to produce detectable quantities in the dropper tip to touch any surface, as this may contaminate the gel. If pain breast milk. Caution should be exercised when ZIRGAN is administered to develops, or if redness, itching, or inflammation becomes aggravated, the nursing mothers. patient should be advised to consult a physician. Patients should be advised 8.4 Pediatric Use not to wear contact lenses when using ZIRGAN. Safety and efficacy in pediatric patients below the age of 2 years have not Revised: April 2014 been established. 8.5 Geriatric Use ZIRGAN is a trademark of Laboratoires Théa Corporation licensed by No overall differences in safety or effectiveness have been observed between Bausch & Lomb Incorporated. elderly and younger patients. Bausch & Lomb Incorporated 12 CLINICAL PHARMACOLOGY Tampa, FL 33637 © Bausch & Lomb Incorporated 12.1 Mechanism of Action ZIRGAN (ganciclovir ophthalmic gel) 0.15% contains the active ingredient, US/ZGN/15/0005 ganciclovir, which is a guanosine derivative that, upon phosphorylation, Based on 9224702 (flat)-9224802 (folded) inhibits DNA replication by herpes simplex viruses (HSV). Ganciclovir

RRO1015_BLO1015_BL ZZirganirgan PPI.inddI.indd 1 99/15/15/15/15 2:372:37 PMPM November

Sunday Monday Tuesday Wednesday Thursday Friday Saturday

12345 OEP Foundation Visual Dysfunctions OEP Foundation VT/Strabismus + Amblyopia

6 7 8 9 10 11 12 OEP Foundation Optometric Glaucoma Society Annual Meeting Academy 2016 Anaheim Visual Dysfunctions AFOS at Academy 2016 Wisconsin OA 2016 Primary Care Symposium OEP Foundation VT/Strabismus + ONS Fall 2016 NC State Optometric Society Fall Congress Amblyopia Educational Symposium

13 14 15 16 17 18 19 NC State Optometric Virginia OA Fall Conference Society Fall Congress California OA Monterey Symposium 2016

20 21 22 23 24 25 26 Virginia OA Fall Conference California OA Monterey Symposium 2016

27 28 29 30

Nov. 2-6, Timonium, MD CE HOURS: 28 Nov. 7-8, Anaheim, CA Visual Dysfunctions LOCATION: Western University Optometric Glaucoma Society HOST: OEP Foundation College of Optometry, 309 E. Second Annual Scientifi c Meeting KEY FACULTY: Robert Hohendorf Street HOST: Optometric Glaucoma Society CE HOURS: 35 CONTACT: Karen Ruder CE HOURS: 8 LOCATION: OEP National Education [email protected] LOCATION: TBD Center, 2300 York Rd., Ste. 113 410-561-3791 CONTACT: OGS CONTACT: Karen Ruder www.oepf.org/oepf_calendar www.optometricglaucomasociety.org [email protected] AM BV VT GL 410-561-3791 www.oepf.org/oepf_calendar EDUCATION TOPICS CS Corneal surgery NO Neuro-ophthalmics RE Retinal disorders AL Allergy CT Cataract surgery NT Nutrition & the eye RS Refractive surgery AM BV VT AM Amblyopia DB Diabetes IN Ocular infections SV Sports vision BV Binocular vision DE Dry eye DS Optical dispensing SD Systemic disease Nov. 3-6, Pomona, CA CM Comanagement EL Eyelids/adnexa PE Pediatric eye care TE Technology VT/Strabismus + Amblyopia CL Contact lenses GL Glaucoma PH Pharmacology UV Uveitis HOST: OEP Foundation CD Cornea/conjunctiva LT Laboratory testing PM Practice mgmt. VT Vision therapy KEY FACULTY: Rob Lewis

REVIEW OF OPTOMETRY DECEMBER 15, 2015 63

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 6363 112/3/152/3/15 1:151:15 PMPM Nov. 7-8, Anaheim, CA AFOS/Academy 2016 HOST: Armed Forces Optometric Society KEY FACULTY: Federal Service Chiefs (Army, Navy, Air Force, VA and IHS) and leading optometric educators CE HOURS: TBD LOCATION: Anaheim Marriott Hotel, NOVEMBER 9-12, ANAHEIM 700 W. Convention Way CONTACT: Lindsay Wright Academy 2016: The OD in ‘The OC’ [email protected] 720-442-8209 hen you think of Anaheim, Dis- Topics will be both in-depth and www.afos2020.org Wneyland may naturally come to broad ranging, covering the entire CD DB GL NO IN PH RE RS TE UV mind, but for 2016, this well-known gamut of ocular conditions and op- Orange County city means Academy tometric responsibilities. Nov. 8, Anaheim, CA 2016, which will be held Nov. 9-12 at In addition, three specialty organi- ONS Fall 2016 Educational the Anaheim Convention Center. zations will hold their annual meet- Symposium Courses at the American Academy ings during Academy. HOST: Ocular Nutrition Society of Optometry’s annual meeting will The Optometric Glaucoma Soci- CE HOURS: TBD be presented by some of optom- ety’s annual scientifi c meeting will LOCATION: TBD etry’s most renowned experts. More be held from Nov. 7-8 in Anaheim, CONTACT: Jeff rey Anshel than 300 CE hours will be off ered, immediately prior to Academy 2016. [email protected] and individual optometrists can earn Eight hours of CE credit will be avail- 800-383-1202 up to a maximum of 37 hours. able. This meeting is by invitation www.ocularnutritionsociety.org Academy 2016 “promises to be an- only. Contact OGS for more details: other exceptional educational experi- www.optometricglaucomasociety.org. Nov. 9-12, Anaheim, CA ence similar to New Orleans in 2015,” The Armed Forces Optometric Academy 2016 Anaheim says Academy of Optometry presi- Society (AFOS) will also be holding HOST: American Academy of dent Joseph P. Shovlin, OD. “There’s a meeting from Nov. 7-8 in Anaheim Optometry a great balance in presenting new in conjunction with the Academy CE HOURS: Total: 300+, Maximum technology and breaking news in meeting. The amount of CE hours to per OD: 37 research for both the clinician who be earned is still to be determined, LOCATION: Anaheim Convention sees patients daily and the vision AFOS says, but topics will cover cor- Center, 800 W Katella Ave. scientist looking for new information nea/conjunctiva, diabetes, glaucoma, CONTACT: Jenny Brown in their area of interest.” neuro-ophthalmic disorders, ocular [email protected] 321-710-3937 www.aaopt.org AL AM BV CM CL CD CS CT DB DE EL GL LT NO NT IN DS PE PM RE RS SV SD TE UV VT

Nov. 11-12, Wisconsin Dells, WI 2016 Primary Care Symposium HOST: Wisconsin Optometric Association CE HOURS: 9 LOCATION: Kalahari Resort & Conference Center, 1305 Kalahari Dr. CONTACT: Joleen Breunig [email protected] 608-824-2200 www.woa-eyes.org GL RE SD LOCATION: Grove Park Inn, Nov. 18-20, Virginia Beach, VA Nov. 11-13, Asheville, NC 290 Macon Ave. VOA Fall Conference NC State OS Fall Congress CONTACT: Adrianne Drollette HOST: Virginia Optometric HOST: North Carolina State [email protected] Association Optometric Society 919-977-6964 CE HOURS: 8 CE HOURS: 18 www.nceyes.org LOCATION: Hilton Garden Inn,

64 REVIEW OF OPTOMETRY DECEMBER 15, 2015

000_1215_ceconference_final.indd 64 12/3/15 1:56 PM infection, pharmacology, retinal disor- two-for-one Tuesday’s ders, retinal surgery, technology and all year long on whale uveitis. For more information on the watching and fi shing trips. AFOS Academy meeting, e-mail ex- Free Fishing Clinic for [email protected] or go to www. Kids hours: every Sunday, afos2020.org. 12pm to 12:30pm. http:// The Ocular Nutrition Society will danawharf.com also hold an educational event imme- • Hike/Mountain Bike in diately prior to the start of Academy an Orange County Park: 2016. For details, contact the ONS at With nearly 40,000 acres [email protected] or of parks, historical and 800-383-1202, and also check www. coastal facilities, and open ocularnutritionsociety.org for meet- space, the Orange County ing details as they become available. Park System features many For more information on Academy opportunities for outdoor SoCal Cuisine 2016 or to register, contact Jenny enthusiasts. Visit the OC Parks web- If you’re looking for some dining Brown, [email protected], or go site for information on all the parks hotspots during downtime at the to www.aaopt.org. and trails in OC. http://ocparks.com Academy of Optometry meeting, take • Huntington Beach Pier and Main your pick from the choices below as Enjoy The OC for Free Street: Said to be one of the premier suggested by Yelp users: While a trip to Disneyland can make spots to catch the perfect South- • The Ranch Restaurant a big dent in your wallet, Orange ern California sunset, Huntington 1025 E. Ball Rd. County—better known as ‘The OC’— Beach Pier and Main Street are iconic www.theranch.com off ers numerous free or almost-free Orange County destinations. www. • Napa Rose activities. (Source: www.visitanaheim. surfcityusa.com 1600 S. Disneyland Dr. org.) • Orange County Great Park Bal- https://disneyland.disney.go.com/ • Angel Stadium Tour: You can loon Rides: The Great Park Balloon is dining/grand-californian-hotel/ embark on a behind-the-scenes tour Orange County Great Park’s fi rst ma- napa-rose of normally restricted areas of ‘the jor attraction. With the ability to hold • Reunion Kitchen + Drink up to 25 to 30 passengers at once Big A.’ For just $7 (or $5 for kids), you 5775 E. Santa Ana Canyon Rd. will get to visit the Angels’ dugout, and soar to 400 feet above the sur- www.reunionkitchen.net visitors’ clubhouse, the Angel Stadium rounding landscape, it also serves as a • Lindo Michoacan 2 press box, dugout suites and more. public observation deck for the Great 327 S. Anaheim Blvd. http://losangeles.angels.mlb.com/ Park’s development. www.ocgp.org/ (714) 535-0265 ana/ballpark visit/balloon • Roy’s Restaurant • Bowers Museum: First Sundays • Orange County’s Farmers’ 321 W. Katella Ave. are free at Bowers. Visitors to the Markets: Shop for fresh, locally grown roysrestaurant.com Bowers can enjoy free access to produce; support local artists, sample • Club 33 the museum, the “Kidseum” and all delicious food of all kinds and listen activities on the fi rst Sunday of every to live music. Farmer’s markets are 1313 S. Harbor Blvd. month. Museum Hours: Tuesday a great way to have fun in the OC www.disneylandclub33.com through Sunday, 10am to 4pm; Kid- sun with the whole family. http:// • Aleppo’s Kitchen seum Hours: Tuesday through Friday, ocagcomm.com/services/markets 513 1/2 S. Brookhurst St. 10am to 3pm. www.bowers.org • Ride the Balboa Island Ferry: This (714) 991-5000 • Fullerton Arboretum: An oasis storied vessel has been transporting • JT Schmid’s in the heart of Orange County, the passengers between Balboa Island 2610 E Katella Ave. arboretum is the premier resource for and Balboa Peninsula since 1919. The jtschmidsrestaurants.com ecological, horticultural and historical historic and scenic trip is a great way • Baci di Firenze Trattoria education. http://fullertonarboretum. to quickly get across the harbor and 416 N. Lakeview Ave. org enjoy the beautiful scenery at the www.bacianaheim.com • Dana Wharf Sportfi shing & same time. You can ride the ferry by • Pappa Hassan’s Grill Whale Watching: Enjoy fun (and free) foot/bicycle or in your vehicle. www. 882 S Brookhurst St. activities for kids every weekend and balboaislandferry.com www.papahassangrill.com

3315 Atlantic Ave. Nov. 18-20, Monterey, CA Conference Center, 350 Calle Principal CONTACT: Bo Keeney, Executive Monterey Symposium 2016 CONTACT: Sarah Harbin; 916-266-5022 Director HOST: California Optometric Assn. [email protected] offi [email protected] CE HOURS: Total: 50, Maximum per www.coavision.org 804-643-0309 OD: 20 AL AM BV CL CT DE GL LT NO NT IN www.thevoa.org LOCATION: Monterey Marriott and DS PE PH PM RE RS TE UV VT

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Sunday Monday Tuesday Wednesday Thursday Friday Saturday

123 UAB Evening of Symposium on Contemporary Eye Care Education Cornea, Contact Lens & Contemporary Vision Care Symposium

45678910 Symposium on Malinovsky Ocular Disease Seminar Contemporary Eye Care Cornea, Contact Lens & Contemporary Vision Care Symposium

11 12 13 14 15 16 17

18 19 20 21 22 23 24 Eastern Caribbean Cruise – A Day in My Retina Clinic

25 26 27 28 29 30 31 Eastern Caribbean Cruise – A Day in My Retina Clinic

Dec. 1, Birmingham, AL Dec. 3-4, Houston Lyon, Kimberly Kohne, Jeff rey Perotti, Evening of Education Cornea, Contact Lens & Contemporary Todd Peabody, Patricia Henderson HOST: UAB School of Optometry Vision Care Symposium CE HOURS: 14 CE HOURS: 2 HOST: University of Houston College LOCATION: IU School of Optometry, LOCATION: UAB School of of Optometry Rawls Hall 100 Optometry, 1716 University Blvd. KEY FACULTY: Jan Bergmanson CONTACT: Cheryl Oldfi eld CONTACT: Amanda Kachler CE HOURS: 16 coldfi [email protected] [email protected] LOCATION: Westin Memorial City, 812-856-3502 205-934-5701 945 Gessner Rd. www.opt.indiana.edu/ce/seminars.htm www.uab.edu/optometry/ce CONTACT: University of Houston CM GL NO PE PH RE SD TE College of Optometry Continuing Dec. 2-4, Lake Beuna Vista, FL Education Dec. 24-31, Eastern Caribbean Cruise Symposium on Contemporary [email protected] – A Day in My Retina Clinic Eye Care 713-743-1900 HOST: Dr. Travel Seminars HOST: Optometric Management http://ce.opt.uh.edu KEY FACULTY: Jay Haynie CE HOURS: TBD CE HOURS: 16 LOCATION: Disney’s Grand Floridian Dec. 5-6, Bloomington, IN LOCATION: departs from Miami Resort & Spa, 4401 Floridian Way Malinovsky Ocular Disease Seminar CONTACT: Robert Pascal CONTACT: Maureen Trusky HOST: Indiana University School of [email protected] [email protected] Optometry 800-436-1028 www.omconference.com KEY FACULTY: S.P. Srinivas, Don www.drtravel.com

66 REVIEW OF OPTOMETRY DECEMBER 15, 2015

0000_1215_ceconference_final.indd00_1215_ceconference_final.indd 6666 112/3/152/3/15 1:181:18 PMPM PROLENSA® (bromfenac ophthalmic solution) 0.07% Brief Summary

INDICATIONS AND USAGE PROLENSA® ophthalmic solution following cataract surgery include: PROLENSA® (bromfenac ophthalmic solution) 0.07% is indicated for the anterior chamber inflammation, foreign body sensation, eye pain, treatment of postoperative inflammation and reduction of ocular pain in photophobia and vision blurred. These reactions were reported in 3 to patients who have undergone cataract surgery. 8% of patients. DOSAGE AND ADMINISTRATION USE IN SPECIFIC POPULATIONS Recommended Dosing Pregnancy One drop of PROLENSA® ophthalmic solution should be applied to Treatment of rats at oral doses up to 0.9 mg/kg/day (systemic the affected eye once daily beginning 1 day prior to cataract surgery, exposure 90 times the systemic exposure predicted from the continued on the day of surgery, and through the first 14 days of the recommended human ophthalmic dose [RHOD] assuming the human postoperative period. systemic concentration is at the limit of quantification) and rabbits Use with Other Topical Ophthalmic Medications at oral doses up to 7.5 mg/kg/day (150 times the predicted human PROLENSA ophthalmic solution may be administered in conjunction systemic exposure) produced no treatment-related malformations in with other topical ophthalmic medications such as alpha-agonists, beta- reproduction studies. However, embryo-fetal lethality and maternal blockers, carbonic anhydrase inhibitors, cycloplegics, and mydriatics. toxicity were produced in rats and rabbits at 0.9 mg/kg/day and Drops should be administered at least 5 minutes apart. 7.5 mg/kg/day, respectively. In rats, bromfenac treatment caused delayed parturition at 0.3 mg/kg/day (30 times the predicted human CONTRAINDICATIONS exposure), and caused dystocia, increased neonatal mortality and None reduced postnatal growth at 0.9 mg/kg/day. WARNINGS AND PRECAUTIONS There are no adequate and well-controlled studies in pregnant women. Sulfite Allergic Reactions Because animal reproduction studies are not always predictive of Contains sodium sulfite, a sulfite that may cause allergic-type reactions human response, this drug should be used during pregnancy only if including anaphylactic symptoms and life-threatening or less severe the potential benefit justifies the potential risk to the fetus. asthmatic episodes in certain susceptible people. The overall prevalence Because of the known effects of prostaglandin biosynthesis- of sulfite sensitivity in the general population is unknown and probably inhibiting drugs on the fetal cardiovascular system (closure of ductus low. Sulfite sensitivity is seen more frequently in asthmatic than in non- arteriosus), the use of PROLENSA® ophthalmic solution during late asthmatic people. pregnancy should be avoided. Slow or Delayed Healing Nursing Mothers All topical nonsteroidal anti-inflammatory drugs (NSAIDs), including Caution should be exercised when PROLENSA is administered to a bromfenac, may slow or delay healing. Topical corticosteroids are also nursing woman. known to slow or delay healing. Concomitant use of topical NSAIDs and Pediatric Use topical steroids may increase the potential for healing problems. Safety and efficacy in pediatric patients below the age of 18 have not Potential for Cross-Sensitivity been established. There is the potential for cross-sensitivity to acetylsalicylic acid, Geriatric Use phenylacetic acid derivatives, and other NSAIDs, including bromfenac. There is no evidence that the efficacy or safety profiles for Therefore, caution should be used when treating individuals who have PROLENSA differ in patients 70 years of age and older compared to previously exhibited sensitivities to these drugs. younger adult patients. Increased Bleeding Time With some NSAIDs, including bromfenac, there exists the potential for NONCLINICAL TOXICOLOGY increased bleeding time due to interference with platelet aggregation. Carcinogenesis, Mutagenesis and Impairment of Fertility There have been reports that ocularly applied NSAIDs may cause Long-term carcinogenicity studies in rats and mice given oral increased bleeding of ocular tissues (including hyphemas) in conjunction doses of bromfenac up to 0.6 mg/kg/day (systemic exposure 30 with ocular surgery. times the systemic exposure predicted from the recommended It is recommended that PROLENSA® ophthalmic solution be used with human ophthalmic dose [RHOD] assuming the human systemic caution in patients with known bleeding tendencies or who are receiving concentration is at the limit of quantification) and 5 mg/kg/day (340 other medications which may prolong bleeding time. times the predicted human systemic exposure), respectively, revealed Keratitis and Corneal Reactions no significant increases in tumor incidence. Use of topical NSAIDs may result in keratitis. In some susceptible Bromfenac did not show mutagenic potential in various mutagenicity patients, continued use of topical NSAIDs may result in epithelial studies, including the reverse mutation, chromosomal aberration, and breakdown, corneal thinning, corneal erosion, corneal ulceration or micronucleus tests. corneal perforation. These events may be sight threatening. Patients with Bromfenac did not impair fertility when administered orally to male evidence of corneal epithelial breakdown should immediately discontinue and female rats at doses up to 0.9 mg/kg/day and 0.3 mg/kg/day, use of topical NSAIDs, including bromfenac, and should be closely respectively (systemic exposure 90 and 30 times the predicted human monitored for corneal health. exposure, respectively). Post-marketing experience with topical NSAIDs suggests that patients with complicated ocular surgeries, corneal denervation, corneal epithelial PATIENT COUNSELING INFORMATION defects, diabetes mellitus, ocular surface diseases (e.g., dry eye syndrome), Slowed or Delayed Healing rheumatoid arthritis, or repeat ocular surgeries within a short period Advise patients of the possibility that slow or delayed healing may of time may be at increased risk for corneal adverse events which may occur while using NSAIDs. become sight threatening. Topical NSAIDs should be used with caution Sterility of Dropper Tip in these patients. Advise patients to replace bottle cap after using and to not touch Post-marketing experience with topical NSAIDs also suggests that use dropper tip to any surface, as this may contaminate the contents. more than 24 hours prior to surgery or use beyond 14 days post-surgery Advise patients that a single bottle of PROLENSA® ophthalmic may increase patient risk for the occurrence and severity of corneal solution, be used to treat only one eye. adverse events. Concomitant Use of Contact Lenses Contact Lens Wear Advise patients to remove contact lenses prior to instillation of PROLENSA should not be instilled while wearing contact lenses. PROLENSA. The preservative in PROLENSA, benzalkonium Remove contact lenses prior to instillation of PROLENSA. The chloride, may be absorbed by soft contact lenses. Lenses may be preservative in PROLENSA, benzalkonium chloride may be absorbed by reinserted after 10 minutes following administration of PROLENSA. soft contact lenses. Lenses may be reinserted after 10 minutes following Concomitant Topical Ocular Therapy administration of PROLENSA. If more than one topical ophthalmic medication is being used, the medicines should be administered at least 5 minutes apart
ADVERSE REACTIONS Rx Only Clinical Trial Experience Manufactured by: Bausch & Lomb Incorporated, Tampa, FL 33637 Because clinical trials are conducted under widely varying conditions, Under license from: adverse reaction rates observed in the clinical trials of a drug cannot be Senju Pharmaceuticals Co., Ltd. directly compared to rates in the clinical trials of another drug and may Osaka, Japan 541-0046 not reflect the rates observed in clinical practice. Prolensa is a trademark of Bausch & Lomb Incorporated or its affiliates. The most commonly reported adverse reactions following use of © Bausch & Lomb Incorporated. 9317600 US/PRA/14/0024

RRP0415_BLP0415_BL PProlensarolensa PPI.inddI.indd 1 33/19/15/19/15 9:569:56 AMAM An NSAID formulated to penetrate target ocular tissues PROLENSA® POWERED FOR PENETRATION Available in a 3-mL bottle size

PROLENSA® delivers potency and corneal penetration with QD efficacy1,2 • Advanced formulation delivers corneal penetration1-3 • Proven efficacy at a low concentration1,4

INDICATIONS AND USAGE PROLENSA® (bromfenac ophthalmic solution) 0.07% is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the treatment of postoperative inflammation and reduction of ocular pain in patients who have undergone cataract surgery. IMPORTANT SAFETY INFORMATION ABOUT PROLENSA® Warnings and Precautions Adverse Reactions • Sulfite allergic reactions The most commonly reported adverse reactions • Slow or delayed healing in 3%-8% of patients were anterior chamber • Potential for cross-sensitivity inflammation, foreign body sensation, eye pain, • Increased bleeding of ocular tissues photophobia, and blurred vision. • Corneal effects, including keratitis • Contact lens wear

Please see brief summary of Prescribing Information on adjacent page. References: 1. PROLENSA® Prescribing Information, April 2013. 2. Data on file, Bausch & Lomb Incorporated. 3. Baklayan GA, Patterson HM, Song CK, Gow JA, McNamara TR. 24-hour evaluation of the ocular distribution of 14C-labeled bromfenac following topical instillation into the eyes of New Zealand White rabbits. J Ocul Pharmacol Ther. 2008;24(4):392-398. 4. BROMDAY® Prescribing Information, October 2012. ®/™ are trademarks of Bausch & Lomb Incorporated or its affiliates. © 2015 Bausch & Lomb Incorporated. All rights reserved. Printed in USA. US/PRA/15/0015

RP0415_BL Prolensa.indd 1 3/19/15 9:54 AM