For Organ Donation Was 18.9%, and 16.7% of Potential Donors Proceeded to Actual Donation
# AVERAGE MEDIAN Thomas Thomas Oral 7 3.33 3.00 Schachtner Schachtner Germany Presenter Score Comments Submitter Topics LD Programs 4 3 requires further studies with a larger Cohort. 3 Left-Sided Donor Nephrectomy Predisposes Living Kidney Donors to Latent Adrenal Insufficiency with Symptoms of Fatigue and Inferior Quality of Life Thomas Schachtner1,2,3, Petra Reinke1,2. 1Nephrology and Internal Intensive Care, Charité Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charité Campus Virchow Clinic, Berlin, Germany; 3Berlin Institute of Health, Charite and Max Delbrück Center, Berlin, Germany Background: The rising prevalence of end-stage renal disease and the chronic organ shortage subsequently calls more people upon to consider living kidney donation. The benefits for living donor recipients and the relative low risk of physical complications for donors have been well documented. The risks of impaired quality of life and particularly symptoms of chronic fatigue, however, remain less well understood and dampen the enthusiasm of living kidney donor outcomes. Material and Methods: We hypothesized that left-sided donor nephrectomy predisposes donors to symptoms of chronic fatigue due to impairment of blood supply of the left adrenal gland. We retrospectively analyzed 356 living kidney donors undergoing nephrectomy from 1998 to 2013, and aimed to address the impact of donation on physical health and quality of life using the standardized short form-8 questionnaire (SF-8). In addition, we prospectively followed 27 living kidney donors 2014/2015 for symptoms of chronic fatigue. Morning cortisol and ACTH levels were performed at baseline, in the first week, and +6 months post donation.
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