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Adult Neurogenesis Is the Production of New Neurons in the Adult Recapitulates Aspects of Brain Development in the Otherwise Brain

Adult Neurogenesis Is the Production of New Neurons in the Adult Recapitulates Aspects of Brain Development in the Otherwise Brain

Adult is the production of new neurons in the adult recapitulates aspects of development in the otherwise brain. In many species (e.g. and birds) it is a common process, non-neurogenic adult brain, and originates from local precursor cells but in mammals it is an exception. Mammalian that reside in defined neurogenic niches. In the , adult Adult neurogenesis takes place primarily in two regions: the SVZ/olfactory bulb system neurogenesis is regulated by behavior and activity. Finally, adult and the hippocampus (as well as the and the neurogenesis contributes to specific types of plasticity in the different Created by Abcam in collaboration with Gerd Kempermann* in some species). It is a highly complex, polygenic process that regions, with regeneration not being its primary purpose.

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*Correspondance to: Gerd Kempermann, M.D., German Center for Neurodegenerative Diseases (DZNE) Dresden and CRTD – Center for Regenerative Therapies Dresden, Technische Universität Dresden, e-mail: [email protected] or [email protected] Copyright © 2018 Abcam, All rights reserved.