January 23, 1990 Vol. XLIJ No. 2 "The Second U.S. Department of Health Best Thing and Human Services About Payday"

National Institutes of Health Recori 'Freedom Is Not Free' President's Visit Lifts NIH Remembers Martin Luther King's Dream Spirits of Patients, Staff Br Carla Garnett By Rich McManus Almost before it began, NIH's 17th annual eran. "I tremble when I chink of his kindness President Bush's 90-minuce visit co the and brilliance. He was a g reat man-a Dr. Manin Luther King, Jr. commemorative NIH campus three days before Christmas left program seemed destined tO be emotional. humble, gentle, man of God . .. a living leg­ patients and caregivers with a strong_ impres­ Just before ir ended, .. Remember the Man . .. end in his own rime." sion of che genuine concern and compassion Remember the Dream" would leave its capac­ Hooks, who walked and worked with King, chat he, his family and administration have for ity crowd singing and cheering in the aisles. gave an eyewitness account of rhe Apr. 3, people with AIDS and_cheir loved ones. "I know you will feel entirely different 1968, night on which King delivered his final Joined by his wife Barbara, their son when you leave here than you felt when you speech ro more than 2,000 listeners ac a George Jr., and DHHS secretary Dr. Louis arrived," predicted NIH Division of Equal Memphis meeting hall. Sullivan and his wife, Ginger, the president Opportunity direnor Diane Armstrong, who "It was a Jark, stormy night," recalled received briefings on AIDS research from cop marked her first King celebration as an NIH Hooks, telling the story with an emotion and NIH auchoricies then spent time with both employee. "You will be spiritually uplifted . ., intensity chat quieted the 500-scac Masur adult and pediatric AIDS patients, urging Jf the enthusiastic response of the audience Audirorium. "It was ominous. We could hear chem co cell him their problems. was an accurate indication, Armstrong's rhe rain hitting the tin roof overhead. We "Two things struck me about the presi­ prophecy proved true. could see chc zig-zag patterns of lightning dent's visit," said Dr. Anthony Fauci, NlAID In a keynote address interrupted often by streak through the stained glass windows. We director and NIH associate director for AIDS rousing applause and laughter, Dr. Benjamin could hear the thunder resound like a thou­ Hooks, executive director of the National sand hungry lions. And we were all wrapped Association for the Advancement of Colored up in the eloquence of Marcin Lurhcr King." People (NAACP), defined the current srnce of According to Hooks, one of the lase chi ngs blacks in America and described the life and King said 22 years ago was char 'there are legacy of King. dark and difficult days ahead.' "I wish you all could have known him," "I wish there was some way I could cell said Hooks, who was introduced by NIH act­ him: You were surely right ... we have had ing director Dr. William Raub as a lawyer, minister, businessman and World War II vet- (See KING, Pa.ge 2 )

Publisher Still Sought CC Nurse Writes AIDS Education Book for Children By Rich McManus Several years ago on the 13th floor of the Like many first-time authors, Montrella has Clinical Center, a nurse caring for an 11-year­ learned how cold and cruel the publishing L()rraine Lamar watches as her son A11sti11. an old g irl with AIDS heard a sentence that world can be. In rhe 2 years since she wrore AIDS patient, gives Presidem Bmh a kiss dt1ring moved her to rears. che text as an adj uncc co graduate nursing his ,w:enl visit lo NIH. The president exchanged The patient, who had acquired AIDS via studies, she has gone from exhilaration to gifts and holiday greetings with both adult and transfusion of contaminated blood, had been depression as various would-be publishers have pediatric AlDS patientJ here. wrestling privately with the implications of taken interest in her work and then subse­ (API\Vide World PholoJ) her diagnosis and could not bear ro cell any of quently abandoned it. At the moment, her friends chat she had AIDS. She was des­ Montrella is considering publishing the book research. "First , it publicly confirms what perately afraid they would chink she had herself. we've all known-chat the president is a gotten the d isease "the bad way. In some respects, the book began when scrong supporter of NIH, particularly of its 'Just cell people chat I am scill me, even Montrella was a teenager g rowing up in Orc­ intramural program here in Bethesda. Second, though I have AIDS," che girl confided co land, Pa., a small town about an hour north it was an excellent example of the president's nurse Karen Montrella of NCI's Pediatric of Philadelphia. empathy and compassion for all AIDS Branch. "l had been a patient on and off for 5 years patients, whether they're children or adults. "J couldn't believe that an 11-year-old when I was a teenager," she related, "and l "He sent a strong signal," Fauci continued, would have such an awareness o[ the social had rerrible nursing care.·· "chat he fully understands chat the virus is che implications of her diagnosis," said Montrella, The awful care she received as an orthopedic enemy, not the people who have the disease." who repaired co her head nurse's office with patient undergoing body cases and rehabilita­ Particularly moving was Bush's participa­ tears in her eyes after the incident. tion prompted her, at age 18, to seek a career tion in a support group meeting for adults That exchange between Montrella and a in nursing. with AJDS on the I Ith floor of the Clinical patient named Andrea was a turning point in "I knew how much of a d ifference it made Center. the nurse's li fe. The phrase " J Am Still Mc," if someone nice and who was good at their job "The discussion was very open an

KING somebody, bur char they are somebody. Dr. Hooks mentioned char blacks muse be about Louis Sullivan, a black physician from rhe business of building coalitions and (Continued from Page JJ Georgia, now is head of che Department of reminded listeners of their responsibility co Health and Human Services. That means he one anocher. some difficult ti mes," Hooks said seriously. conrcols the second largest budget in govern­ "Nothing chat black folks wane in chis Then he continued, teasingly, "l cau cell we ment, behind defense. world can they get by themselves," he said. are in n pogc .> The Record January 2i, 1990

Initiative To Reduce Frailty in Seniors Announced by NIA, NCNR

By Karen McCrory Pocinki At a recent congressional briefing, Dr. T. studies will examine ways to prevent falls and franklin Williams, director of the National fractures and will test exercises to improve lnsticute on Aging, and Dr. Ada Sue strength and mobii ity in older persons. In Hinshaw, director of the National Center for addition, NlA/NCNR grantees will look ac Nursing Research, announced a ioim initiative how nutritional, hormonal and ocher interven­ to reduce frai lty in older pe::rsons. The:: goals of tions improve functional capability. chis cooperative research effort are co improve Other research efforts will focus on assess­ the quality of life for older people and to ment instruments used by researchers co reduce the need for long-term care in chis measure disability, rehabilitation potential and country. functional improvement in response co · Although frailty is widespread among older therapy. These instruments can help health Americans, it is nor inevitable. The NIA/ care providers develop individualized preven­ NCNR-supporced studies will rest a number tion strategics and appropriace supportive of promising interventions to prevent fra il ty services. Such interventions can increase an and ro reduce the late-life disability and older person's independence and reduce long­ dependency it causes. term care needs. "The rime is right for a health promotion Researchers have predicted chat, by the year program to reduce the need for long-term care 2000, federal expenditures for long-term care Dr. Ste11en M. Schnittman, a senirtr Jtaj/ fellow in for che g rowing number of older persons ," will increase tenfold. The N IA/NCN R initia­ N IA JD's Laboratory of l,mmmoregulatitm, was seated Rep. Edward R. Roybal, chair of che tive may lessen che impact of this staggering recen1fy granted one offour 1989 Young lnvestiga- house select committee on aging, at the open­ forecast. 1or Awttrds from 1he Amerimn Society frtr ing of the briefing. H inshaw pointed ro a growing national Microbiology. HiJ mettrch on the immu­ Problems of streng th, mobility, balance and awareness of che need to understand health nopatho?,enesiJ of human immunodeficiency vims has endurance can prevent an older person from promotion in relation to older people. significantly enhanced the 1111dentanding of how performing daily activities most people cake "Health problems, especially chronic illness, HI V ca11JeS damage to the im11111ne syJtem. His cur­ for granted such as bathing, dressing and pre­ frequently limit rhe functional independence rent research interem focm on identifying HIV­ paring meals. Because of physical limitations, of older people," noted Roybal. "The costs infected cells in periphe,·a/ blood and quantifying many older people need a cane or walker to associated with chronic illness place a severe the viral load in HJV-infected individuals over provide support or maintain balance. Hun­ burden on patients, their fam ilies and on the time. He iJ applying polymeraJe chain reaaion tech­ dreds of thousands suffer serious injuries­ economy." nology 10 characterize cells that are actively such as hip fractures-due co falls. Among According to Williams, "The goal of chis expressing vims as well as /hose that are latently people 75 and older, 32 percent have diffi­ joint research effort is to help improve the infected with HIV. This work iJ instrumental to culty climbing a flight of srairs; 40 percent functioning and independence of frail older efforts to design treatmentJ against HIV. can't walk two blocks; and 22 percent can't people and ease che personal burden of lift 10 pounds. Almost half of nursing home frailty." At the same time, research can residents require assistance to get our of a enhance the quality of long-term care in this Smithsonian Offers Chaos Course chair or bed because they are so physically country and reduce the enormous cost of that frail. care. 0 The Smithsonian Institution, in collabora­ Five million older persons in this country tion with the Washington Evolutionary need long-term care, and a large share of their Systems Society, is sponsoring an eight-session care needs arc re laced to physical frailty. H ow­ course on "Chaos," rhc new mathematical con­ ever, new data indicate chat frailty can be cept chat may indicate rhe underlying order reduced. For example, one study has shown rhat determines seemingly random, natural that exercise can markedly improve the lim­ behaviors. The 90-minure sessions, held Mon­ ited walking ability of very frail nursing home days at 8 p.m., through Mar. 19 (except Feb. residents. Another study showed chat a falls L9), follow the Chaos movement from its sci­ prevention program in the home significantly entific and philosophical roots to its various reduced the number of falls in older people. applications including "Chaotic Meca­ At the briefing, members of Congress an

BOOK nities for just che sort of book she was Last March, the elation of che preliminary writing. acceptance d issolved into depression as a cor­ (Continued from Page I.J Inviting her best friend from high school, porate merger put her project in limbo. Montrella chose a career in cancer nursing artist Christopher Dwyer, to illustrate her " ! was really tired at chat point and ready because, "l knew rhac cancer was worse than book, Montrella had, by the winter of 1988, a to quit unless something miraculous opened whar I had as a kid." She came co NIH full-color mockup of / Am Still Me co pass up," Montrella said. almost 5 years ago tu work in the Pediarric around to publishers. Meanwhi le, parents of patients on 13 ·w est Branch, and in 1987 began caring fur chil­ The first house co see ic couldn't promise had gotten wind of rhe book. They liked che dren- both babies and adolescenrs-wich either full-c:olor printing or national distribu­ way the diary dealt with the emotional aspects AlDS. tion, so it dropped the project in spice of of the vims and how the reacher's guide sup­ "People were real nervous about (AIDS pro­ favorable reviews by che "Reading ls Funda­ plied the facts. Slowly, a groundswell of tocols) at first," she remembers. "! had mental" program at the Smithsonian support began to build. yualms ac the beginning, bur I couldn't imag­ lnstirurion. Lase summer, emboldened by the parents' irre nor caking care of a sick child. I just support, Montrella showed the book co some decided co be real careful, wear g loves, and children's advocacy organizations, which chal­ not do things fusr." lenged her co publish the book herself. When she met the young girl named Looking co NIH for resources, she found And rea (who has since died and co whom her Randy Schools, general manager of che R&W, book is dedicated), Momrella was studying co and CI administrative officer Kathy Russell become a nurse practitioner and was enrolled as strong allies in the effort ro raise funds; in graduate school at the University of Mary­ both have long and d istinguished records of land at Baltimore. One of her assignments was piloting projects that help ochers. a paper on social support for children with Settling on prices of $4. 95 for the book and cancer versus children wich AIDS. That paper $8.95 for the reacher's manual, Montrella has became a precursor to / Am Sri/I Me. begun co raise money for the project, which "I wrote the book on a kid's level in diary will be put our by a nonprofit organization form," she recalls. " I took the poim of view· of she calls Lierle Voices. a IO-year-old girl who was afraid ro lee people "I had co get very business smart in the last know about her illness. Each entry in the year," Montrella relates. "I got cynical enough diary was based on real issues." to realize chat everything in publishing Once she adopted a theme, Montrella wrote revolves around money,'' quickly, finishing the 16-page cexc in several Kann Montrella Endorsements for rhe project have, so far, weeks. Convinced char education is the key co come from authorities in their fields. Dr. Phi­ getting people over their paranoia about "Our lawyer suggested raking it ro rhe big lip Pizzo, chief of the Pediatric Branch, has AlDS, she composed with Andrea's story in publishers," Monrrella said, "which became put his clout behind ir, as has the National the back of her mind. the most interesting process of my entire life. " Education Association. Several ocher promi­ The diary's last page is a poem char rhe g irl The first major publisher to see it rejected nent medical and political leaders have been writes about her pn,dicamenc. Montrella says ic our of hand, claiming the issues, rhe scory asked co lend their prestige co che project. che verse came co her during a commuce and the little girl were not real. "Our target markets are schools, hospitals, between grad school and home. "It was a very humbling experience, but it libraries and communities," Montrella says. "I stopped in a McDonald's parking lot in motivated me more," said Montrella. "Rejec­ "The book applies to all kids. There's a uni­ Laurel, Md., co get my ideas on paper before 1 tion followed rejection and I felt really versal message chat applies co children with lose chem," she remembers. "Thoreau ha

(Continued from Page 4 ) Viral Pathogenesis Is Theme of Rowe Symposium I think J could write a book about the book." Having just returned from a 3-month The sixth annual Wallace P. Rowe Sym­ Berns, human parvoviruses; Dr. Marshall internship in Memphis, when: she completed posium on Animal will be held Feb. Bloom, Aleutian mink disease virus; Dr. studies to become a nurse practitioner, 5-6 in che Lister Hill Auditorium, Bldg. Roberr Lamb, influenza and parainfluenza Montrella was supposed to spend the next 6 38A. The program begins with opening viruses; Dr. Kathleen Coelingh, human para­ months in the Philippines establishing a remarks at 8:45 a.m. on Monday, Feb. 5; the influenza type 3 virus surface g lycoproceins health care clinic. final presentation is at 3:30 p.m. on Tuesday, and ; and Dr. Charles Rice, sindbis "I had been planning for the past 2 years t0 Feb. 6. Preregistration is not req uired . virus. go, bur political unrest in the Philippines can­ Sponsored by NIAJD, the symposium On che second day of che symposium, Dr. celed it,., she said. "This was going co be my honors the lace Dr. Rowe, who was an inter­ Edward Hoover will discuss feline leukemia year of adventure and travel. Bm it has nationally recognized authority on animal virus and immunodeficiency; Dr. Janet worked our for the best that I couldn't go. 1 virology. Rowe was chief of the Laboracory of Hartley, murine immunodeficiency disease feel like rhe book is my baby, and I want co Viral Diseases at NIAID from 1968 until his virus; Dr. Irvin Chm, the molecular generics sec it through." death in 1983. of human T-cell lymphocrophic virus; Dr. Ac the moment there is little doubt that I The theme of chis year's symposium is Beatrice Hahn, che cytopachicicy of human J\m Still Me will be published. But if all else ·'Viral Pathogenesis." lnternarionally renowned immunodeficiency virus-2; Dr. Dale McFarlin, fails, Montrella says she's learned "two major investigators will review findings from their human T-cell lymphocrophic virus-! and neu­ lessons-patience and perseverance." research. On the firsr day, Dr. Bernard Moss rologic disease; Dr. Steven McKnight, lf her ability to make the best of adversity will discuss vaccinia virus; Dr. Laimonis herpesvirus; and Dr. Harold Ginsberg, is any benefit to her pat,cnts, perhaps it's best Laimins, human papillomavirus; Dr. John adenovirus. D chat Montrella is still Montrella. 0 Taylor, hepatitis delta virus; Dr. Kenneth

Cystic Fibrosis Lectures Announced at Lipsett A series of Wednesday afternoon lectures in Mar. 2 l-M.J. Welsh-Chloride channels New Pub Trims NIH Wasteline Lipsett Amphitheater will probe recent in CF respiratory cpithclia developments and new trends in the study of Mar. 28- R.J. Crystal-Gene expression \Vi1steli11e, a new publication produced by cystic fibrosis (CF), the most common fatal and modulation in pulmonary epithelia rhe Environmental P roceccion Branch of che generic disease of children in the United Apr. l8-D.A. Ausiello--Regulation of Division of Safety, will be introduced co the Scates. W ith the recent discovery of che CF ion channels: The role of G-protcins, phos­ N IH community this month. The focus of gene, interest in the lecnue series is expected pholipids and cycoskelecal components WIastelin e will be co provide a practical per­ co run high. Apr. 25-P.S. Aronson-Taxonomy of spective on waste reduction and disposal issues The first two lectures on the molecular anion cransport systems in epichelia for specific work areas and operations at NIH. genetics of CF will be presented on Jan. 3 1 May 9-Q. Al Awqaci-Molecular proper­ Distribution of each issue will be railored to and Feb. 7 by Drs. John R. Riordan and Lap­ ties of chloride channels work areas most affected by the specific topic Chee Tsui, two of the lead investigators from May 2 3-R. D ..Camerini-Otero--Homolo­ covered in chat issue. The first issue will the Hospital for Sick Children in Toronrn who goL1s recombination: From bacteria ro man address waste chemical disposal options for the identified the CF gene. June 6-S.L. Alper-Molecular cell biology lab, how co minimize chemical waste and the On Feb. 2 l, Dr. R. Michael Blaese of NCl of anion exchangers services available co make chis job easier. will discuss and its prospects for June 20-R.C. Boucher-The relationship Waste paper n:ducrion and recycling initia­ CF. The remaining 10 lectures will focus on of CFTR co sodium transport in airway rives are currently prominent both locally and more specific aspects of CF, which is charac­ epithelia terized by chronic lung and digestive disease, June 27- A. R. Beaudet- Genetics of cystic and copious, chick mucus that must often be fibrosis cleared from the lungs. For more information, call 496-3435. CME T he lecture series, organized by visiting credits are available. D scientisc Dr. loav Cabantchik in NIDDK's Laboratory of Cell Biology and Genetics, is WASTELINE sponsored by NIDDK and che Cystic Fibrosis Porter Heads Epilepsy Groups Foundation. le is the fifth rime in as many across the country. By targeting the distribu­ years chat NIDDK and the CF Foundation Dr. Roger J. Porter, NINOS deputy direc­ tion of W,uteline, DS hopes ro reinforce the have collaborated to present lectures on CF. tor, has been elected to head two professional need co minimize the amount of general waste A complete listing of the lectures, which epilepsy organizations: the l ,500-member generated at NIH. It is our hope chat employ­ all begin at 3 p. m., follows. American Epilepsy Society and che Jnterna­ ees will apply these practices in the workplace tional League Against Epilepsy, a group chat as wel l. Jan. 3 1- J.R. Riordan- Molecular proper­ sponsors international scientific conferences. WIaJteline is printed on recycled paper t ies of the CF gene One of his goals will be co strengthen links provided by NlH's Printing and Reproduction Feb. 7-L-C. Tsui--T he molecular between professional societies and lay and Branch (PRB). For advice about printing ocher generics of CF patient support groups. Porter, an expert on jobs on recycled paper, call George Mendez, Feb. 2 l-R.M. Blaese--Prospects for epilepsy drugs, said raking leadership duties 496-6077, of PRB. human gene therapy in such societies allows NIH scienrists "co Employees are encouraged to suggest ideas Mar. 7- R.A. Frizell-Modulation of chlo­ understand better our constituenrs and our for future issues of WaJteline by ca lling Gyula ride channels in secrecory epirhelia mission."' 0 Kovach, 496-3537. D page 6 The Record January 2.\, 1990

BUSH Bush's Commitment, C (Continued from Page JJ

While President Dush's recent visit to chil­ from all of rhe patients, noc just rhe few who spoke up at first. Ir wasn't just a y uick photo dren with AIDS and their families may have opportunity where he came in, shook hands lifted the patients' spirits and encouraged rheir then left. He asked appropriate questions and parents, the occasion may also have delivered insisted on hearing from everybody. Even an equally important and deeper message to when his scaff told him ir was time to leave, Al OS researchers and caregivers. he wanted co scay and listen co their "Originally, we had been cold that rhe pres­ problems. ident would spend only about 10 minutes "The men themselves were g reatly moved with us," said Dr. Philip Pizzo, chief of NCI's by the obvious compassion of the president," Pediatric Branch. "The face that he accually he added. "The exchange was full of warmth." stayed well more than 30 minutes symbolizes Fauci, who has twice demurred from Bush's both his interest in and his commicmenc w enrreaties ro become che next N IH direcror, this illness and the heal ch of these patients." spoke with the president about recent research President Bush met with Pizzo and a group advances against AJDS; also offering updates The /int lady enjoys he,· 111eeti11g with a you11g of abom nine families, which included chil­ were NCI director Dr. Samuel Broder and Dr. patient. dren of a variety of ages- from coddler co Philip Pizzo, whose NCI Pediatric Branch ceen-who have traveled from various loca­ cares for youngsters with AIDS. tions around the councry co be created ac T he president publicly declared that Fauci NIH. All of the children arc involved in pro­ was one of his modern-day heroes during che family support group. And both remind,-'

Preside!// and M,:r. Bush sat in on a support gro11p meetillg far ad11/ts with AIDS. asking many q11estiom Preside/// 1md M11. Bush ask the opinion of a yott118 and exprming sincere co11cern for the patients. port g.-oup di.rrmsion. page 7 TreRecord January 23, 1990

":ompassion Draw Praise

expressed a keen interest in our work here and the president seemed very pleased and upbeat." "I chink rhe objective of che visit, from the point of view of the president and Dr. (Louis) Sullivan and ochers who planned it," explained Pizzo, " was for the president co have some direct contact wirh the children and t heir fam­ ilies and, also, to gain a clearer understanding of the d isease itself." Acrnrding ro Pizzo, Bush's exchanges with the patients included quesrinns abour their experiences with AIDS and the different aspects of rhc illness. "He asked some of them if they had experi­ enced any discrimination in their hometowns because of their illness," Pizzo related. "In some cases the answer was yes and, in ocher NCI director· D,·. Sa11wel Broder ( I) briefs the president and first lady on the latest A IDS research advances. cases, no. Looking on are Dr. A,11ho11y Fauci (c) and DHHS secretary Dt·. Louis S11/liva11 (,). Pizzo also gave Bush a brief overview of NIH's current work on t reatments for pedi­ atric AIDS. ''We've created in excess of 1.30 children from more than 30 States," said Pizzo, sum­ marizing his remarks t0 Bush. "The numbers are increasing quickly and they are going ro increase significantly in the year ahead, bur we have seen some improvements afrer our rreat­ mcnrs-especially in the area of encephalopathy (a degenerative brain disease that affects pediatric AIDS paticncs)--and we have been able co improve the quality of life. ··--carJa Garnett

The president makes a 11e!I' friend on I 3 \11/eJI . Greeting M,1. 811sh is Dr. H . Clifford Lme, sen­ ior i1111estigato1· in NIA/D's Lab11Ya/01y of lnmumoreg11/a1ion. Looking on is 1111rse La11ra Gwrmi. tl'ha a!J11 helps care for ad11/ts u·ith AlDS.

The President's Pocketknife

The formal pare of the visit with che par­ had been g iven boxes of candy, but only the ents an

Hasselmeyer Retires After 29 Years with PHS New Cut Sheet Duplex Printer Assistant Surgeon General Eileen G . The NIH Computer Center, a component of Hasselmeyer retired recently after more than the Division of Computer Research and Tech­ 29 years of active duty with the Public Health nology, offers single-sided and double-sided Service Commissioned Corps, 26 years of (duplex) printing on cut sheer paper using the which were spenr with che National Institute new 3827 laser printer. Computer Center of Chi Id Health and Human Development. users have exercised chis new printer's During her last assignment, she was associ­ capabilities for everything from single-page ate direcror for scientific review, N ICHD, and memos co reports of several thousand pages. special assistant to the director, National Cen­ Double-sided output produced on the 3827 ter for Nursing Research. prinrer is borh aeschecically pleasing and a Hasselmcyer, a l946 graduate of the Belle­ "space saver. .. f or example, people in the vue School of Nursing, received a baccalau­ grants community have noted char double­ reate degree in education, a master of science sided printing of summary sheers results in degree in administration and the docror of attractive reports char take up half the space of philosophy degree in nursing science from Eileen /-lmsel111eyer (I) reaives bet' admiral's flag older listings. Even more compact archival New York Universiry. from NCNR 's La11ra James .ti a retirement cere­ listings can be produced with double-siJed following a 10-ycar association with the mony. Looking on is 0 . Mane Henry. PHS chief output in smaller I 5-characcers-per-inch NYU pediatric 1.1ccabolic and nutritional 11m,e officer. characrcr sets. The excellent print quality of research service, she joined the PIIS Division the 3827 printer is a boon when printing of Nursing Resources in l956 and was princi­ NICI-ID review system for both grants and g raphic Olltpm, such as charts created via pal investigacor for the Behavior Patterns of contracts that was independent from the TELL-A-GRAF or SAS/GRAPH . Premature Infants Project- the division's first institucc's program administration functions, Output proJuced on the 3827 laser printer clinical research study of the relationship in accordance with NIH policy. In 1981 she is suitable for all types of manuscripts, reports between nursing care and patient welfare. achieved the rank of rear admiral. and manuals. Printing can be requested in Challenging the nursing practice of minimal Hasselmeyer was awarded a National League portrait ("rail") or landscape ("wide") format handling for prematurely born infants and for Nursing Commonwealth fellowship and an on 81/i-by- l l- inch paper, or in portrait format using methodologies developed in the clinical NIH special research fellowship, and has also on 81/i-by- l l-inch tluee-holc- punched paper. research study. Hasselmeyer demonstrared in been the recipient of research grants from the le is worth noting that double-sided printing 1962 char increased sensory and kinesthetic American Nurses foundation, Sigma Theta on the three-hole-punched paper is perfect for input was beneficial ro these babies as shown Tau and the Connecticut scare health depart­ storage or Jistribution in three-ring binders. by weight gain, decreased crying and longer ment. In 1980 she received the NYU Health Printing on the 3827 costs rhe same as any periods of continuous sleep. Professions Creative leadership Award. In May ocher output printing services of the Computer When N ICHD was established in 1963, she 1989, Hasselmeycr received the PHS Mcr­ Center. was appointed special assistant co the director icorious Service Medal in recognition of her To request 3827 printing via WYLBUR, (for prematurity) and served in various admin­ many achievements during a distinguished simply specify a cut sheet form name in a istrative, review and program positions, career, including her conrriburions to the LIST command; the cut sheet form names arc including the positions of direcror, Perinatal esrablishment of the National Center for Nurs­ 900P for portrait format, 900L for landscape Biology and Infant Mortality Program, and ing Research at NIH. format, and 999P for three-hole-p unched por­ chief, Pregnancy and Perinatology Branch. On In recognition of her contributions co the trait format. Add rhe option DUPLEX co rhe detail from NlCHD in 1968-69, she was advancement of research on the sudden infant LIST command co request double-sided print­ appointed the Annie W. Goodrich professor of death syndrome, the Sudden lnfant Death ing of the output. For more information about nursing at Yale University where she studied Syndrome Alliance has established che Ei leen using the 3827 cue sheet printer, see the the cardiorespiracory responses of premature G. Hasselmeyer Award co recognize individ­ Computer Center Users Guide or call the PAL infants co gavage feeding. uals who have significantly advanced the Unit consulrams at 496-5525 between 8:30 Hasselmeyer was responsible for developing knowledge and understanding of SIDS. The a. m. and l p. m. Monday through Friday. for the sudden infant death syndrome research ini­ alliance is a federation of volunteer agencies a consulting appointment regarding a specific tiative in the Department of Health, char promotes and supports research on SIDS. computing task, such as how to upload a Education, and Welfare for wh ich she received The award includes a $5,000 prize and a WordPerfect file to the mainframe for printing the PHS Cornmendarion Medal. Between medallion. The first award will be made chis on the 3827 cut-sheet printer, contact rhe I 977 and 1984, she was projecr officer for the month. Compurer Ccnrer Training Unit, NICHD cooperative epiderniologic study of In retirement , Hasselrneyer has volunteered 496-2339 D to serve as executive direccor for rhe Uni­ sudden infant death syndrome (SIDS) risk fac­ Atlantic City Trip, Mar. 16 tors. The study population included more rhan formed Services University for the Health 800 babies who died suddenly and unexpec­ Sciences College of ursing cask force, which Circle Mar. 16 on your calendar, because tedly and more than 1,600 living babies. is carrying ouc a study to determine the feasi­ that's che day you'll be able co try your luck. f rom rhis study a descriptive profile has bility of establishing a coll ege of nursing R&W and Adventures Unlimited have put emerged chat associares several maternal, neo­ offering both undergraduate and graduate pro­ together a crip ro rhe Castle Casi no in Atlantic natal and poscneonatal factors with increased grams at USUHS. She will continue co be City. Cose for the trip is $25, but you gee SIDS risk. involved in activities related co nursing and co S 17. 50 of rhat back in coin! Bus will leave When Hassdmeyer was appointed associate the support of SIDS research, but she also NIH Bldg. 3 IC parking lor at 7 a.m. and director for scientific review in 1979, she was plans co "rake time co smell rhe roses" and return co NIH at approximately 9 p. m. Call g1v<:n responsibility for establishing an enjoy her grandniece and grandnephew. 0 lt96-4600 for more information. 0 page 9 ~Record January B , 1990

Manuel Miranda Is Named Sons of Italy Hold Talk NIA Assistant Director The Order Sons of Italy in America NIH Dr. Manuel R. Miranda has been named Lodge will sponsor a special lecture as pare of assistant director for incerdisciplinary its Festival of the Spirit series. The speaker research at the National Institute on will be Dr. Wilhelmina .Jashemski, professor Aging. He will coordinate the inscitute's emeritus of history at che University of Mary­ research efforts wich ocher inscirntions and land and an incernationally known scholar. organizations, add co rhe emphasis on The title of her calk will be "The Gardens minority aging and training issues, assist of Pompeii and the Area Destroyed by Ves­ in the coordination of che NIA's planning uvius." Her presentation will focus on her and legislative processes and advance inter­ quarter century of excavations leading co the national research opportunities. idc-mificacion of che flora excanc at che time of Miranda formerly served as staff director the famous eruption by Mr. Vesuvius. The for the U.S. House of Representatives seminar will be held in Lipsett Amphitheater, select committee on aging, where for the .... Bldg. LO, Thursday, Feb. I at noon. All are past 2 years he coordinated legislative At the a111111al meetings of the Academy of DemislY)' invited. activities for 65 congressional members and lnterna1io11al and the American College of Dentim. In addition, rhe Lodge of OSIA thanks all Dr. TetTell Ho/fe!tl was awarded fellowship Sla- 45 staff persons. He has been a faculty J. who participated in che Italian Fesca on Dec. 11/J in ea(h of these ho,101· 1wg,111izations. 1--/offeld is member of the University of California, 12, despite che prospects of heavy snow. As a exeC11t111e secretary of the 1wo s11bco111111itteeJ of the Los Angeles, in the school of social welfare result of the food sales, $500 will be donated oral biology and medicine m,dy seclion in the Refer­ since 1978, and was on leave from chat ro che Friends of the Children's inn. The win• ral and Review Branch of the Division of Re.search ner of the lamp raffle- is Louis Figliozzi. Mem­ Granls. bership information abour the Lodge is avail­ able from Nina. 496-0754. D

Administrative Officer Patricia Greenfield Retires

Patricia L. Greenfield, administrative officer for the Division of Concraccs and Granes, OD, retired recencly after more than 3 5 years of service. She joined NIH in J anuary 1959, following a tenure of more chan 4 years with che Department of the Army ac Ft. Detrick in Frederick, Md. Through 1971, Greenfield worked in several positions in NIDDK. In l97 l , she joined NIAID and served as com­ miccee management officer until 1973, when Dr. Manuel R. Miranda she became an adminisrracive officer with NIMH. In 1979, Greenfield became admin­ position co head the congressional istrative officer for che Division of Concraccs comrniccee. and Granes. From early 1984 through July of 1985, During the past 10 years, she handled che Parriria C reenfield Miranda was a visiting sciencisc at NIMH, numerous operational needs of one of che where he conducced an analysis of NIMH­ Office of Administration's most complex divi­ funded research on Hispanic mental healch. sions. During her tenure, division tle insight inco her plans by announcing she He has also held teaching positions ac responsibilities grew dramatically in scope and was "going to avoid l-270" but ac the same the University of Minnesota; California complexicy, including significant increases in time she was going to "travel throughout che Scace University, San Jose, and the Univer­ staff, the advenc of the feder.11 Acquisition United Scates anJ abroa

Nathan W. Shock Dies; Led Research on Aging 'ANALYZE' Imaging Software at NIH NIH collaborators are currently being Dr. Nathan W. Shock, 82, the dean of sought co use ANALYZE, a powerful software American gerontologists and retired scientific package foe the analysis of medical images. direccor of the National lnstirute on Aging, Mayo Clinic's biodynamics research unit, died of cancer Nov. 12 at a hospital in developer of ANALYZE, working through Baltimore. DCRT's Computer Sysrems Laborarory, is Jn 1941, Shock came co Baltimore and hoping N IH researchers will aid in the joined rhc first research program on aging in development of new applications. This UNIX­ NJH. From lY4 I co l964, he directed a unit based software package cakes sequences of CT, of the NIH physiology division. He then .MR I, PET or ocher scanner images and com­ worked with the National Institute of Child bines rhem into a 3D image, which is then Health and Human Development, directed the manipulated and measured. The easy-co-use, pioneering Gerontology Research Center and menu-d riven software allows images to be spent a year as scientific direccor ar NI A rotated and enlarged and cross sections at before retiring in 1976. arbitrary angles produced. Elements such as The gerontology research program evolved skin or bone can be enhanced or removed with from one run by Shock and a technical associ­ Dr. Nathan IV. Shock ANALYZE, thereby revealing structures such ate to an NIA intramural program with 200 For example, men's life expectancy between as organs by sekccing for or against defined sciencists and researchers. Over the years, he l900 and 1975 increased from 47. 9 years co image intensity levels. Many more manipula­ also helped direct the posrdoccoral training of 69. 5. Y ec the work of Shock and others rions and measurements are performed using more than 200 gerontology and geriarrics pointed our char this seemingly dramatic the numerous tools in ANALYZE, which also researchers. increase was mainly due co the drop-off in performs analysis of 2-dimensional images. A Since 1976, he had held the title of scien­ childhood deaths. H is studies pointed out char "movie mode" allows users ro flip through tist emeritus ac N l A's Gerontology Research a man who reached 65 years in 1900 could multiple images, like frames in a movie, pro­ Center in Baltimore. He remained active in expect to live l l. 5 more years; one who ducing an animated effect. scientific research until his death. · reached char age in 197 5 could expect to live Researchers who would like a demonstration From 1959 co 1970, he also had served on an estimated 14 more years. of ANALYZE should call Jim Sullivan, the National Academy of Sciences' atomic He was an effective advocate for spending 496-5362. Further information on ANALYZE bomb casualty advisory board. and research in his branch of health science. can be found in an article published in the President of the Gerontological Society of While it is pointed our rhac gerontology may J u ne 1989 issue of Research Resources America from 1960 tO 196 l, he also had been not have the drama or immediacy of orher Repo,-1er. D its publications committee chairman and edi­ health questions, it is a field chat will affect a tor-in-chief of the j o11rnal of Gerontology. From huge percentage of the population. 1969 to 1972, he was president of the Inter­ Shock, who lived in Towson, was a native Talk on Human Rights in China national Association of Geronrology. He also of Lafayette, Ind. He received a hachclor's A lecture on "Human Rights in China: had served as a division president of the degree in chemical engineering from Purdue Perspectives and History," will be held American Psychological Association. University in 1926 and a master's degree in Feb. 15 from l2:30 to 1:30 p.m. in Masur He was a recipient of high awards from the organic chemistry from chere the following Audirorium, Bldg. IO. Speaking will be Gerontological Society, the American Geri­ year. He received a docrorate in physiological Shengping Feng, executive d irector of the atrics Society, the American Heart Association psychology at the University of Chicago in China solidarity committee, and Esrrellica and the old Department of Health, Educacion l930. H e was affiliated with che University of Jones, a scudenr of Asian affairs for Amnesty and Welfare. In June, NIA renamed its intra­ California at Berkeley before moving co Internacional. The lecture is sponsored by the mural Gerontology Research Center in his Baltimore. medical scicncists committee; for more honor. His wife of 60 years, Margaret Truman information call Genevieve Schiffman, Shock was editor of the Classified Biblio[1.rt1- Shock, clied in April.. His survivors include 496-1 156. 0 phy of Ge,·ontolngy and Geriafl•irs pubI ished by cwo sons, Joseph Baird Shock of Timonium Stanford University Press in 195 l, l957 and and John H oward Shock of Alexandria; a sis­ 1963. He was rhe author or coauthor of more ter. Beatrice S. Hargett of Hesperia, Cal if.; than 350 tethnical papers dealing with the seven grandchildren and two greac-grand­ NHLBl's 'Stanley' Honored chemistry, biology and psychology of aging. children.- cou rtesy Washi11gto11 Post NHLBL's L989/90 public service announce­ Among the areas he and his colleagues ment, "Stanley" (stroke victim), has been Save on R&W Membership explored was the physiology of aging in the awarded a "certificate for outstanding heart, kidneys, lungs, nerve and brain. They You can save on a 1990 R&W membership creativity" by the judging panel for che clocked the different rares thac different parts now through the end of January during the Mobius Broadcasting Awards, which are pre­ of che body age and documented the face that R&W membership drive. During chis rime sented to outstanding PSAs and commercials people age at vascly d ifferent rares. memberships are discounted co $Ii (beginning from around rhe world. This year, winners Over the years, Shock used science, com­ Feb. l, chey will be $5). In addition, all who were selected from 30 countries. Only 10 per­ mon sense and nor a linlc humor co educate join

=TRAINING TIPS Nick Carter Dies, Former NIEHS Scientific Director Dr. Charles E. (Nick) Carter, who served as The NIH Training Center of the Division scientific director of NIEHS from 1979 co of Personnel Management offers the following: 1985, d ied 0cc. 31 at his home in Water­ Co11neJ and ProgramJ Dates ville, Ve. During his long career in science, Carter did extensive research in biochemistry, Management and S11pervisory 496-6371 pharmacology and in areas of nucleic acids and Crt::icive Basics for Changing Workplaces 1/25 chemotherapy. Good Stares: Transition Planniog 2/2 Working \Xlich Personal D ifferences As scientific director Carter was senior sci­ MUTI ll 21 14 ence administrator for intramural research at Introduction to Supervision 3/5 N IEHS. He held this imporrant posr during a Congressional Operations Workshop 3112 period of rapid instirure growth, anJ was Ncrworking: Silent Policies 3/20 responsible for consolidating anJ streamlining Positive Influence 312 1 Effective Communications 3127 laboratory organization. Before joining N IEHS, Carter had govern­ Or. Chades E. C,mer Office Ope,·ations Training 496-62 11 ment service with rhe NarionaJ Cancer Jnmxlucrion rn Working ac NIH for Institute, che Ammie Energy Commission and School of Medicine and at Case Western New Support Scaff 2/5 Delegated Acquisition 3/12 rhe Department of Energy, as well as Oak Reserve School of Medicine in Cleveland , Telephone Techniques 3/12 Ridge National Laboratory. He also served where he was director of the department of Voice and Diccion lmprovemenc 31 19 academic appointments at Yale University pharmacology. Training and Development ServiceJ 496-62 11 Personal Computer training is available through User Resources Center (URC) self study courses. T here is no cosc co N tH employ~es for these hands~on sessions. Topping 'Recollections' on Sale Parade Marshals Needed The URC hollrs arc: Monday 8:30 a.m. - 7 p. m. RecollertionJ, a new book written by former Plans are well under way for the annual Tues. Wed. Thucs. 8:30 a.m. - 7 p. m. N IH associate d irector Dr. Norman Topping Bethesda-Chevy Chase Parade on Sunday, Friday 8:30 a.m. - 4:30 p.m. wirh Gordon Cohn, is now available from the May 6. The parade begins at NIH . Parking Sa, urday 9 a.m. - I p.m. Universiry of Southern California Press. lor 16, near the Library of Medicine, will be Training Center, DCRT, and orher craining Topping, who is perhaps best known for his used as the scagi ng area. information is avai lable on WYLBUR. Logon rickecrsial diseases research char included pre­ Parade organizers are looking for a group of ro WYLBUR and type ENT ER T RAINING paring an antiserum against Rocky Mountain 10 co 20 volunteers co work ar che staging spocced fever anJ leading the N IH efforr dur­ area on the day of the parade. Volunteers ing World War IJ to develop a vaccine against should have a rake-charge personality and a epidemic typhus, served as associate director of good sense of humor. Responsibilities include NIH from 1948 co 1952 checking in parade units, giving lase minute Copies of Recollections may be obtained for instructions, lining up the units in parade $ 18 each by writing ro Topping Recollections, order and starting the parade. 1r is a hectic, 1420 San Pablo Screer, Rm. A302, Los chaotic, but fun job' Angeles, CA 90033-104 2. 0 Volunteers will need co attend one planning meeting and be available on chc day of rhe parade from 9 a.m. co 3 p.m. If you (or your g roup) is interested, please contact Randy White House, Cathedral Tours Schools, 496-606 I. D We Washingtonians tend co cake for granred al l chat our ciry has co offer. 1f you're g ui lty of it, maybe R&W can help. We've arranged for tours of two arrractions, both free of charge. On Sarurday , Feb. 1, 50 Nll-l'ers can cour The Divi.ri,m of t ogistirs, a p,m of OD's Office of the Whirc House. The g roup will meet at the AdJ11i11istrct1io11 , nxe111fy homrred I 02 employees at Visitors Entrance on East Executive Ave. at 8 ilJ third am11"1l tlll'ardr reremony. J oh11 I:. Gree11 a. m. (Tour takes approximately 30 minures.) (second from L). foreman of the u,a,·ehouse sectio11 . And on Sarnrday, Mar. 17 , we'll tour t he Su!>Jily /3ra 11ch. recein,s a 11 employee of the month sixth largest cat hedral in the world, the rJll'ard f,-om Non11a11 L. Osinski. director. arq11isi­ Washingron Cathedral. This cour will begin ar tinn ma11agenm11 . Looking OJI ctre Robert /\1. 10 a.m. at the Northwest Cloister entrance of t''laJt1((i ( / ). d,rector. Di11isi1m of LovstitJ. IJl/d the Cathed ral (off North Rd.) and will lase N II-/ ,w,,date direttor fr11· 11d111imstratio11 J ohn D. approximately :$ 0 minutes. Anit

NIH Searches for Director of New Office of Education NIH Day Care Surveys Due For several years, NIH's intramural pro­ dinace its efforrs with the individual BID Tht: NIH day care surveys were distributed gram, in common with many other research programs to assure that pocential candidates to employees in early January. Due to several insriturions, has seen a decline in rhe number are aware of the many opportunities at NIH. reports of sporadic delivery, employees who of young Americans preparing for careers in The office will conduct surveys and analyses did not receive a survey should call the Divi­ biomedical research. The reasons for rhis viral co effective targeting of recruitment sion of Space Management, 496-3 172. All decline are complex, but they are evident at a activities and will explore various ways to employees are encouraged to complete the sur­ time in the history of biomedical research improve postgraduate training and education vey. If you do not currently have child care or when the scientific needs and opportunities opportunities. Trainees will be assisted in eldt:r care needs, simply respond to che first have never been grearer. There has been an identifying future job opportunities. two questions on the survey. All surveys are co especially significant decrease in the numbers A search is now under way for the director be received by space management before J an. of physicians who plan to embark on research of chis office. Candidates muse hold a doctoral 30. careers, bur there is a decline in the numbers degree and be very familiar with the intra­ Darn analysis should be complete in March . of Ph.D.'s as well. mural prograrns- laboracory as well as At that t ime open forums will be scheduled NIH is crearing a new Office of Education clinical. An interest in recruitment and educa­ and publicized for various locations ·co review as one pare of a strategy to reverse these tion is essential. However, no prior experience chose findings with interested employees. trends. The office wi ll provide a focal point in these areas is required. The office will be a The concern for day care at NIH extends for NIH recruitment efforts- maximizing pare of the Office of the Deputy Director for beyond the campus boundaries. Thanks co the effectiveness in attracting out standing bio­ Intramural Research. lt will coordinate its efforts of a Westwood day care committee, medical research trainees across institute lines. activities with the NIH ed ucat ion committee, responses to the Westwood edition of the NIH The office will organize broad, intensive and and with specialized BID recruitment and day care survty are being collected. Some of innovative recruiting efforts; it will help can­ rrai ning programs. the preliminary comments address t he basic didates identify all possible opportunities at further information about chis new position issues of high quality and affordable child N IH and g uide them through the process of may be ohcained from Susanne Stoiber care, cider care, as well as fac ilities for chil­ selection. There will be a high level of per­ (496-9428), who is aiding Dr. J. Edward dren with special needs. sonal contact with applicants as the office Rall, N lH deputy director for intramural The overwhelming position of those who assists chem in navigating the complexity of · research, in organizing the office. A copy of wrote comments has been in favor of a day che campus and the intramural craining oppor­ the vacancy announcement may be obtained care facility at Wcsrwood. An example of tunities. The office will interact with young from Paul Thibault of OD personnel chose endorsements is as follows: people ac all levels- from high school through (496-652 l). Applications should be submirted "Day care should be a necessity for the NIH graduate and professional schools. le will coor- by Feb . 5. 0 staff. Most important it should be quality care at an affordable race or subsidized on a sliding Stipends Available Through FAES scale and should include faci lities for infants and toddlers." FAES is administering special funds known Attracting and retaining quality employees as W ellcome Stipends to aug ment the stipends is a government-wide problem. The issue was of postdoccoral level guest workers ar NIH . voiced by borh supervisors and employees as Dtpending on the weal funds chat are avail­ evidenced below: able and the number of eligible applicants, a " Affordable, quality day care on the job-sire maximum of 53 ,600/ yt:ar ($300/ month) may will help retain quality employees at the be granted ro each approved individual as an NIH ." income supplement to a maximum coca! fam­ " As a supervisor, I believe rhe only way co ily income of$ l5,000/year plus S 1,000 for assure chat we can arr race good cmp!O)'Ce5 is to each dependent including spouse . provide day care." The selection committee will consider the " [ am planning a fum ily in the next year. scientific merit of che research co be conducted Whether I can find adequate day care will as well as need and professional qualifications make the difference about whether I stay at of t he applicant. NIH or not." Awards wi ll be made twice a year, Mar. 31 Finally, child care's true value was adeptly NC/'1 Division of Exfllm111r,d Aaivities collected and Sepe. 30 , for the 12-month periods begin­ seated in the following response: Jil(fre than 100 toy1 for the HoNse of Rlllh during ning Apr. l and Oct. 1, respectively. "If day care w as provided ac all of the NIH Christmas. Affording to Dr. \Vil11a A. Woods . i11 Applications for 1990 muse be received in t he sites, I feel char rime and attendance would the pa11. the division had exchanged small gifts FAES office on or before Feb. 23 for the improve immensely. Peace of mind is worrh a ,11110111; themselves and decided this yea,· to do sot11e• March awards or on or before Aug . 24 for the pot of gold and these parents will have peace thmg ///Ore prod11aive. " \11/e asked everyone to bring September awards. Applicacions are being of mind knowing their little ones arc secure a tr;y and place it i11 r1 box at 011r ,1111111al accepted now for rhe awards co be made on close by ... Chris1111as Pttrty. E11e1yone romplied and some people Mar. 3 1. The response from N IH employees ar West­ e1·en b1w,gh1 more than r,11e. It u1orked .w 1.l'el! ll'e Additional application forms are available wood has been better tha n expected. le is ll'ill probably do it a?,ai11 next year ... sttul \'(foods. from the FAES Business Office, Bldg. 10, hoped that similar results will be realized The Ho11se of Rmh is a she/te,· f()r abmed children Rm. BICIS or by calling 496-7976. □ when the remainder of N IH employees com­ and battered ll'iNJ. Presenting the IIIJS lo Al plete the survey.-Donal<.J L. Bordinc D 1'11/1011 Ir) from the Hal/Se ,,f R111h are (j,-0111 I) B,1rbara Odle. W,,ods ,//Id Bob Kmth.