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HIV-AIDS Assignments Grade 11
Oral History Center HIV/AIDS in American History Assignments – Grade 11 September 2020 For more information on curriculum, see the Oral History Center website. Table of Contents OVERVIEW ......................................................................................................................................... 2 PODCAST EPISODE 1 ........................................................................................................................... 2 THEMES .......................................................................................................................................................... 2 ASSIGNMENT: WORKING WITH THEMES IN THE HIV/AIDS INTERVIEWS ..................................................................... 3 Preliminary sample assignment: AIDS campaign.................................................................................... 3 FOUR POSSIBLE ASSIGNMENT TOPICS ................................................................................................. 3 ASSIGNMENT 1: WOMEN ON THE FRONT LINES: GENDER, IDENTITY, AND VALUES ....................................................... 3 Sample curriculum ................................................................................................................................... 4 Sample assignment ................................................................................................................................. 7 ASSIGNMENT 2: VIRUS HUNTERS: THE SEARCH FOR HIV ........................................................................................ -
Department of Health and Human Services National Institutes of Health
DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH RECOMBINANT DNA ADVISORY COMMITTEE MINUTES OF MEETING September 12-13, 1994 TABLE OF CONTENTS I. Call to Order/Dr. Walters II. Chair Report on Minor Modifications to NIH-Approved Human Gene Transfer Protocols/Dr. Walters III. Chair Report on Accelerated Review of Human Gene Transfer Protocols/Dr. Walters IV. Minutes of the June 9-10, 1994, Meeting V. Data Management Update/Dr. Smith VI. Discussion Regarding Criteria for RAC Review and Approval of Human Gene Transfer Protocols/Dr. Varmus VII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Transfer Protocol Entitled: A Phase I Study of an Adeno-Associated Virus-CFTR Gene Vector in Adult CF Patients with MildLung Disease/Dr. Flotte VIII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Transfer Protocol Entitled: Gene Therapy for the Treatment of Metastatic Breast Cancer by In Vivo Infection with Breast-Targeted Retroviral Vectors Expressing Antisense C-Fos or Antisense C-Myc RNA/Drs. Holt and Arteaga IX. Addition to Appendix D of the NIH Guidelines Regarding a HumanGene Transfer Protocol Entitled: Evaluation of Repeat Administrationof a Replication Deficient, Recombinant Adenovirus Containing the Normal Cystic Fibrosis Transmembrane Conductance Regulator cDNA to theAirways of Individuals with Cystic Fibrosis/Dr. Crystal X. Amendments to Sections I, III, IV, V, and Appendix M of theNIH Guidelines Regarding NIH and FDA Consolidated Review of Human Gene Transfer Protocols/Drs. Wivel and Noguchi XI. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Transfer Protocol Entitled: A Pilot Study of Autologous Human Interleukin-2 Gene Modified Tumor Cells in Patients with Refractory or Recurrent Metastatic Breast Cancer/Dr. -
Adenovirus Replication Is Coupltd E with the Dynamic Propernes of PML Nuclear Structure
Downloaded from genesdev.cshlp.org on October 5, 2021 - Published by Cold Spring Harbor Laboratory Press Adenovirus replication is coupltd e with the dynamic propernes of PML nuclear structure Vassilis Doucas, 1,s Alexander M. Ishov, 2 Anthony Romo, 1 Henry Juguilon, l'a Matthew D. Weitzman, 4 Ronald M. Evans, 1'3 and Gerd G. Maul 2 ~The Salk Institute for Biological Studies, La Jolla, California 92037; 2Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania 19104; 3Howard Hughes Medical Institute, 4Institute for Human Gene Therapy, University of Pennsylvania, Philadelphia, Pennsylvania 19104 USA Wild-type PML and at least four other novel proteins are localized within discrete nuclear structures known as PODs. We demonstrate here that during adenovirus infection, immediate early viral proteins from the E1 and E4 transcription units associate with the POD, which in turn undergoes a dramatic morphological change. During this process, the auto-antigen Sp-100 and NDP55 but not PML, relocate from the POD to the viral inclusion bodies, the sites of adenovirus DNA replication and late RNA transcription. The E4-ORF3 11-kD protein alone will induce this reorganization and reciprocally, viruses carrying mutations in the E4-domain fail to do so. These same viral mutants are defective in viral replication as well as the accumulation of late viral mRNAs and host cell transcription shutoff. We show that interferon (INF) treatment enhances the expression of PML, reduces or blocks PODs reorganization, and inhibits BrdU incorporation into viral inclusion bodies. In addition, cell lines engineered to overexpress PML prevent PODs from viral-induced reorganization and block or severely delay adenovirns replication. -
Vital and Health Statistics; Series 4, No. 11
NATIONAL CENTER Series 4 For HEALTH STATISTICS I Number 11 VITAL amd HEALTH STATISTICS DOCUMENTS AND COMMITTEE REPORTS PROPERTYOF THE PUBLICATIONS8F?ANC~ EDITORIAL LIBMY use of hospital data for Epidemiologicand Medical-Care Research A Report of the United States National Committee on Vital and Health Statistics How hospital data may be used for epidemiologic and medical- care research is discussed with examples of past applications. U.S. DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE Public Health Service Health Services and Mental Health Administration Washington, D. Cl. June 1969 Public Health Service Publication No. 1000-Series 4 -No. 11 For sale by the Superintendent of Documents, U.S. Government Printing Office Washington, D. C., 20402- Price 25 cents NATIONAL CENTER FOR HEALTH STATISTICS THEODORE D. WOOLSEY, Director PHILIP S.LAWRENCE, SC.D., Associate Director OSWALD K. SAGEN, PH.D.>, Assistant Director for Health Statistics Development WALT R. SIMMONS, M.A., Assistant Director for Research and Scientific Development ALICE M. WATERHOUSE, M.D., Medical Consultant JAMES E. KELLY, D. D. S., Dental Advisor EDWARD E. MINTY, Executive O//icer MARGERY R. CUNNINGHAM, Information O//icer OFFICE OF HEALTH STATISTICS ANALYSIS IWAO M.MORIYAMA,Ph.D.,Di~ector DEAN E. KRUEGER, Deputy Directo~ Public Health Service Publication No. 1000-Series 4-No. 11 Library of Congress Catalog Card Number 70-600272 FOREWORD This report, prepared by a Subcommittee of the U.S. National Committee on Vital and Health Statistics, views the development of hospital data in the United States and discusses how they may be used for epidemiologic studies of chronic disease, for disease surveillance purposes, and for medical-care research. -
U.S. DEPARTMENT of HEALTH and HUMAN SERVICES Public Health Service National Institutes of Health RECOMBINANT DNA ADVISORY COMMIT
U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Public Health Service National Institutes of Health RECOMBINANT DNA ADVISORY COMMITTEE Minutes of Meeting -- March 1-2, 1993 TABLE OF CONTENTS I. Call to Order II. Minutes of March 1-2, 1993, Meeting III. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Therapy Protocol Entitled: Gene Therapy for the Treatment of Malignant Brain Tumors with In Vivo Tumor Transduction with the Herpes Simplex-Thymidine Kinase Gene/Ganciclovir System Drs. Culver and Van Gilder IV. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Therapy Protocol Entitled: Phase I Study of Gene Therapy for Breast Cancer Dr. Bank V. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Transfer Protocol Entitled: Administration of Neomycin Resistance Gene Marked EBV Specific Cytotoxic T Lymphocytes to Recipients of Mismatched-Related or Phenotypically Similar Unrelated Donor Marrow Grafts Drs. Heslop, Brenner, Rooney VI. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Transfer Protocol Entitled: Assessment of the Efficacy of Purging by Using Gene-Marked Autologous Marrow Transplantation for Children with Acute Myelogenous Leukemia in First Complete Remission Drs. Brenner, Krance, Heslop, Santana VII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Therapy Protocol Entitled: A Phase I Trial of Human Gamma Interferon-Transduced Autologous Tumor Cells in Patients with Disseminated Malignant Melanoma Dr. Seigler VIII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene Therapy Protocol Entitled: Phase I Study of Non-Replicating Autologous Tumor Cell Injections Using Cells Prepared with or without Granulocyte- Macrophage Colony Stimulating Factor Gene Transduction in Patients with Metastatic Renal Cell Carcinoma Dr. -
Local Health Departments and HIV Prevention
May 14, 2018 USPSTF Senior Coordinator ATTN: USPSTF Nominations Center for Evidence and Practice Improvement, Agency for Healthcare Research and Quality 5600 Fishers Lane Mailstop 06E53A Rockville, MD 20857 Re: Nomination of Dr. Tomás Aragón for Membership to the U.S. Preventive Services Task Force On behalf of the National Association of County and City Health Officials (NACCHO), I write to nominate Dr. Tomás Aragón, Health Officer of the City and County of San Francisco, and Director of the Population Health Division for the San Francisco Department of Public Health (SFDPH), to serve as a member of the U.S. Preventive Services Task Force (USPSTF). NACCHO is the voice of nearly 3,000 local health departments across the country. These city, county, metropolitan, district, and tribal departments work every day to promote and protect the public’s health and safety in places where people work, play, travel, worship and live. Dr. Aragón is an experienced public health executive, leader, and medical epidemiologist with demonstrated expertise in prevention, clinical medicine, epidemiology, and academic research. Since 2011, Dr. Aragón has directed core public health services for San Francisco, including epidemiology; surveillance; disease and injury prevention and control; health promotion; environmental health; performance (quality) improvement; maternal, child and adolescent health; public health emergency preparedness; and emergency medical services. San Francisco is home to 850,000 residents and serves a population of 1.5 million during the day. SFDPH has 8000+ employees and includes acute medical and trauma care, primary care, long-term care and rehabilitation, mental health, substance use, and core public health. -
View, Or Three- Dimensional Orientation, for Each Particle in the Image Stack
STRUCTURAL INSIGHTS INTO RECOGNITION OF ADENOVIRUS BY IMMUNOLOGIC AND SERUM FACTORS by JUSTIN WAYNE FLATT Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy Dissertation Adviser: Dr. Phoebe L. Stewart Department of Pharmacology CASE WESTERN RESERVE UNIVERSITY May, 2014 CASE WESTERN RESERVE UNIVERSITY SCHOOL OF GRADUATE STUDIES We hereby approve the thesis/dissertation of 4 JUSTIN WAYNE FLATT G 4 candidate for the A DOCTOR OF PHILOSOPHY a degree*. (signed) a JASON MEARS A (chair of committee) A PHOEBE STEWART a A ANDREAS ENGEL A A SICHUN YANG D A AMY RUSCHAK A (date) A DECEMBER 13, 2013 A *We also certify that written approval has been obtained for any proprietary material contained therein. ii To Victoria and Samson. iii TABLE OF CONTENTS List of Tables…………………………………………………………………………….xii List of Figures…………………………………………………………………………...xiv List of Abbreviations…………………………………………………………………….xx Acknowledgements……………………………………………………………………..xxv Abstract……………………………………………………………………………………1 Chapter 1 Introduction and background………….…………………………………..3 1.1 Adenoviruses, from pathogens to therapeutics…………………………....3 1.1.1 Adenoviruses as pathogens………………………………………………..3 1.1.2 Adenovirus structure and cell entry……………………………………….5 1.1.3 Adenoviruses as therapeutic agents……………………………………….9 1.2 Adenovirus-host interactions…………………………………………….10 1.2.1 Host immune response to adenovirus……………………………………...11 1.2.2 Recognition of adenovirus by human alpha defensin 5……………….....12 1.2.3 Recognition of adenovirus by serum factors…………………………….15 -
M.Sc Ist Yr MICROBIOLOGY a Bottle of Wine Contains More Philosophy Than All the Books in the World
M.Sc Ist yr MICROBIOLOGY A bottle of wine contains more philosophy than all the books in the world. -Louis Pasteur JANUARY 2022 M T W T F S S Ferdinand Cohn (Founder of 31 1 2 Bacteriology and Microbiology) Global Family Day 3 4 5 6 7 8 9 Richard Rebecca Har Michael Craighill Gobind Krause Lancefield Khorana Rebecca Craighill Lancefield (well known for serological classification of β- hemolytic streptococcal bacteria) 10 11 12 13 14 15 16 National Indian Youth Day Army Day 17 18 19 20 21 22 23 Bacillus cereus Bacillus cereus is a facultatively anaerobic, toxin producing, gram- positive bacteria that canm be found in siol vegetation anf even food. This may cause two types of intestinal illness, one diarrheal, and 24 25 26 27 28 29 30 one causing nausea and vomiting.It Ferdinand National Heinrich World can quickly multiply at room Kohn Tourism Anton de Leprosy temperature. B.cereus has also been National Girl Day Bary Day Child Day Republic implicated in infections of the eye, respiratory tracts , and in wounds. International Day B.cereus and other members of Day of Education bacillus are not easily killed by alcohol,they have been known to World Leprosy Day – 30th JAUNARY: World Leprosy colonize distilled liquors and Day is observed internationally every year on the last Sunday of alcohol soaked swabs and pads in January to increase the public awareness of leprosy or Hansen's numbers sufficient to cause Disease. This date was chosen by French humanitarian Raoul infection. Follereau as a tribute to the life of Mahatma Gandhi who had compassion for people afflicted with leprosy. -
Emerging Viruses: the Evolution of Viruses and Viral Diseases Author(S): Stephen S
Emerging Viruses: The Evolution of Viruses and Viral Diseases Author(s): Stephen S. Morse and Ann Schluederberg Source: The Journal of Infectious Diseases, Vol. 162, No. 1 (Jul., 1990), pp. 1-7 Published by: Oxford University Press Stable URL: http://www.jstor.org/stable/30127833 Accessed: 18-08-2014 21:02 UTC Your use of the JSTOR archive indicates your acceptance of the Terms & Conditions of Use, available at http://www.jstor.org/page/info/about/policies/terms.jsp JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact [email protected]. Oxford University Press is collaborating with JSTOR to digitize, preserve and extend access to The Journal of Infectious Diseases. http://www.jstor.org This content downloaded from 155.58.212.160 on Mon, 18 Aug 2014 21:02:31 UTC All use subject to JSTOR Terms and Conditions 1 Fromthe NationalInstitute of Allergy and Infectious Diseases, the FogartyInternational Center of the National Institutesof Health, and the RockefellerUniversity Emerging Viruses: The Evolution of Viruses and Viral Diseases Stephen S. Morse and Ann Schluederberg From the Rockefeller University,New York,New York,and the National Institute of Allergy and InfectiousDiseases, National Institutesof Health, Bethesda, Maryland Challengedby the sudden appearanceof AIDS as a major rus and host can follow severalpossible lines, and pathogens public healthcrisis, the National Instituteof Allergy and In- may not always evolve towardslower virulence. -
Background of the Field
© Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION PART I Background of the Field 78903_ch01_5807.indd 1 11/10/10 5:06:36 PM © Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION 78903_ch01_5807.indd 2 11/10/10 5:06:36 PM © Jones & Bartlett Learning, LLC. NOT FOR SALE OR DISTRIBUTION CHAPTER 1 Introduction: The Environment at Risk content areas of environmental health such as air quality, LEARN I NG OBJECT I VES water quality, food safety, and waste disposal. By the end of this chapter the reader will be able to: Maintaining environmental quality is a pressing task for • Describe how environmental health problems influence our the 21st century. Improvement in environmental quality is an lives official goal of the US government, as articulated in Healthy • Describe the potential impacts of population growth upon the environment People 2010. This goal (number 8, Environmental Health) is • State a definition of the term environmental health formatted as follows: “Promote health for all through a healthy • List at least five major events in the history of environmental environment.”1(p55) A list of environmental objectives is shown health in Table 1-1. Note that Healthy People 2020, which will provide • Identify current issues in the environmental health field updated objectives, was not available as of this writing. • Describe employment opportunities in the environmental health field According to Healthy People 2010: Physical and social environments play major roles in the health of individuals and commu- INTRODUCTION nities. The physical environment includes the air, water, and soil through which exposure to This chapter will illustrate how environmental health relates chemical, biological, and physical agents may to our lives and delimit the scope of the environmental health occur. -
Library Prize for Undergraduate Research
UCLA Library Prize for Undergraduate Research Title Medical Denialism: Where Must Society Draw the Line? Permalink https://escholarship.org/uc/item/6vk348sc Author Mally, Alison H Publication Date 2015-04-01 Undergraduate eScholarship.org Powered by the California Digital Library University of California Alison Mally Honors Collegium 14 Medical Denialism: Where Must Society Draw the Line? Introduction From germ theory to modern physics, the continual questioning and challenging of the established norm has been the source of scientific progress and growth. In fact, science would not be where it is today without its history of opposition to the prevailing paradigm. However, not all challenges to established medical fact are productive, and in fact, can be very dangerous. In some cases, particularly in medicine, publicly and vocally opposing and challenging what has been well established and supported has dire consequences, costing innocent lives. Thus, the question is raised: At what point does it become unacceptable to deny well-established medical fact? This investigation seeks to answer this question through a series of case studies. To show when a challenge to the established norm is not only acceptable, but vitally important to the progress of medical science, the example of the establishment of germ theory is presented, particularly through the contributions of John Snow and Robert Koch. First, the prevailing medical theories of the time will be described, followed by a description of John Snow’s investigation of cholera during the epidemic in London in the mid-19th century. His investigation will be shown to have challenged those medical theories which dominated at the time, but that this was done with the support of meticulously gathered evidence. -
Mobile Health Teams, Decolonization, and the Eradication Era in Cameroon, 1945-1970 Sarah Cook Runcie
Mobile Health Teams, Decolonization, and the Eradication Era in Cameroon, 1945-1970 Sarah Cook Runcie Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Graduate School of Arts and Sciences Columbia University 2017 © 2017 Sarah Cook Runcie All rights reserved Abstract Mobile Health Teams, Decolonization, and the Eradication Era in Cameroon, 1945-1970 Sarah Cook Runcie This dissertation examines the intersecting changes of African decolonization and the post-World War II internationalization of public health by showing how Cameroonian and French health officials shaped global health programs on the ground in the 1950s and 60s. I approach this topic through the lens of two tightly interwoven developments in Cameroon: the history of colonial mobile health teams created by French military doctors and the advent of postwar global disease eradication campaigns. While colonial medicine and international health are typically treated as distinct historical subjects, I argue that global disease eradication programs in this period in Cameroon relied entirely on colonial mobile health teams and their reformulation after independence as a basis of infrastructure, personnel and knowledge. I specifically assert that Cameroonian and French health officials positioned mobile health teams as cornerstones of national health policy and regional health coordination in Central Africa and, in turn, as the basis for operations of attempted global disease eradication programs within Cameroon. As Cameroonian, French and international health officials negotiated the work of the mobile health teams through decolonization and the first decade of the independence, they were moreover charting new structures of authority and control over medicine and public health between the global and the local, and forging an international politics of public health rooted in the particular tensions of decolonization in the country.