Prognostic Factors for Outcome and Survival after Laparotomy in Patients with Pancreatic Trauma: One Single-center Experience. Chao Yang Jinling hospital Baochen Liu Jinling hospital Cuili Wu Jinling hospital Yongle Wang jinling hospital Kai Wang jinling hospital Weiqin Li Jinling hospital weiwei ding (
[email protected] ) Jinling hospital https://orcid.org/0000-0002-5026-689X Research Keywords: pancreatic trauma, prognosis, risk factor, logistic regression analysis Posted Date: April 9th, 2020 DOI: https://doi.org/10.21203/rs.3.rs-21555/v1 License: This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Page 1/13 Abstract Background: Pancreatic trauma results in signicant morbidity and mortality. Few studies have investigated the postoperative prognostic factors in patients with pancreatic trauma after surgery. Methods: A retrospective study was conducted on 152 consecutive patients with pancreatic trauma who underwent surgery in Jinling Hospital, a national referral trauma center in China, from January 2012 to December 2019. Univariate and binary logistic regression analyses were performed to identify the perioperative clinical parameters that may affect the morbidity of the patients. Results: A total of 184 patients with pancreatic trauma were admitted during the study period, and 32 patients with nonoperative management were excluded. The remaining 152 patients underwent laparotomy due to pancreatic trauma. Sixty-four patients were referred from other centers due to postoperative complications. Abdominal bleeding caused by pancreatic leakage ( 10 of all deaths) and severe intra-abdominal infection (12 of all deaths) were the major causes of mortality. Twenty-eight (77.8%) of the 36 patients who had damage control laparotomy survived.