researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021

3 Canada’s Top 50 Research Universities 10 Canada’s Innovation Achievements INSIDE 6 Leaders’ Corner 13 Canada’s Top 40 Research Hospitals 8 Focus on COVID-19 Research 15 Canada’s Top 50 Research Colleges 9 Researchers’ Corner 19 Canada’s Top 100 Corporate R&D Spenders

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I g n n n i o t a v r a b ti e on el C I Worth C L Society under threat: research, capacity and response Decades of capacity building has strengthened Canada’s research response to everything from pandemics and earthquakes to floods and cyber threats

By Debbie Lawes research on virology, immunology and “Pandemic preparedness hasn’t really clinical trials in every hospital, and to (UBC) and former Executive Director at infectious disease, as well as translational been a thing in Canada,” said Murthy, collect and share data in real time across VCHRI, the research arm of Vancouver s Canada’s research community research – taking the information that who has worked on the frontlines for a hospitals to understand how an outbreak Coastal Health and a health partner of equipped to respond when a national we already have from basic science and number of infectious disease outbreaks, is spreading and how patients respond to UBC. crisis hits? This not-so-hypothetical applying it to disease,” said Houghton, including Ebola in West Africa. “Other different treatments. It’s an issue Murthy One trial is led by Dr. Josef Penninger, question was put to the test early in who pivoted his lab last year to work on a countries have departments and research knows well as the co-lead on the World a medical geneticist at UBC who was I COVID-19 vaccine. Manufacturing it in institutions dedicated to that. Canada has Health Organization’s CATCO study, the one of the first researchers to start clini- 2020 when a mysterious and deadly virus began its rapid spread around the world, Canada, however, could be problematic. had small projects dedicated to pandemic world’s largest randomized control trial cal trials in Europe on a new COVID-19 forcing governments everywhere to shut- One of the biggest gaps in Canada’s preparedness and the public health infra- on COVID-19 therapeutics. drug. While studying SARS 15 years ago, down borders, schools, and businesses, pandemic preparedness continues to structure dedicated to it but hasn’t had cancel surgeries and ban family gatherings. be a lack of a domestic manufacturing the large-scale preparedness work that COVID-19 isn’t the only existential capacity to produce sufficient doses for other places have.” We have a lot of expertise in Canada threat facing humankind these days but both clinical trials and to inoculate every Like Houghton, Murthy believes that can help with pandemic preparedness unlike slower moving crises like climate Canadian. Getting there, said Houghton, Canada’s biggest strength is its scien- DR. SRINIVAS MURTHY change, it is one that steadfastly refuses requires a national vaccine manufactur- tific community, specifically in fields like “Health Research Foundation of Innovative Medicines Canada Chair to be ignored or put off as hospital ICUs ing plan to attract a big drug manufac- antibodies and vaccine research. How- in Pandemic Preparedness Research; Investigator, BC Children’s Hospital quickly become overwhelmed and the turer or scale-up domestic companies. ever, he said the complexity of Canada’s death toll climbs. “We cannot be dependent on other health system – notably having 10 prov- The ability of society to successfully countries when such a large-scale pan- inces with their own individual health “Right now most of the patients that Penninger co-discovered an enzyme respond in times of crisis depends on demic is underway,” he said. “Knocking systems and approaches to data manage- have COVID-19 are not in academic which allows the virus to infiltrate healthy how well a country has prepared for such out 30 million vaccines for the Canadian ment and sharing – makes it difficult for hospitals, they’re in community hospitals cells, particularly the lungs. That discov- emergencies. Increasingly, such plans population is no trivial matter, and the Canada to translate that knowledge into that don’t do research traditionally,” he ery led to the development of a drug to must include a nation’s vast scientific number could be much higher. We might action as an emergency is underway. explained. “As such, they don’t have block the enzyme and stop the virus. He enterprise – from those working in state- need two or three doses so that’s about “We have a lot of expertise in access to the data infrastructure that aca- is now using that knowledge to develop a of-art research facilities as well as start- 100 million doses we would need. To do Canada that can help with pandem- demics do with more downtown urban similar drug to fight COVID-19. up companies and large multinationals, that needs a lot of planning and quite a bit ic preparedness,” he said. “They’re hospitals. We need to link all of our A combination of factors made it to those who fund the research and shape of investment.” already driving a lot of the agenda at hospitals and care pathways together so possible for VCHRI to respond quickly, the policies that support such activities. we can respond better and faster when said McMaster, including rapid response “The government has responded well We need to boost funding for basic there’s an outbreak.” grants from CIHR, emergency federal by freeing up money through the Canadi- research on virology, immunology and infectious disease, funding to keep research staff employed an Institutes of Health Research (CIHR) BC’s Coordinated and a single ethics approval process for as well as translational research for both diagnostic vaccine as well as Response the whole province. “ DR. MICHAEL HOUGHTON therapeutic programs for COVID-19. The Vancouver Coastal Health Research Coordination has also been critical. 2020 Nobel Laureate Canada is really punching easily its Director, Li Ka Shing Applied Virology Institute Institute (VCHRI) is a clinical trial pow- Starting in March, the BC COVID-19 weight if not above,” said University of University of Alberta erhouse, having overseen 320 trials in Research Coordination Initiative hosted Alberta virologist Dr. Michael Houghton, 2019 involving some 1,500 research- by UBC was struck to identify research who won the 2020 Nobel Prize in Physi- Preparing for the high level organizations like the World ers and trainees. It’s now fighting on priorities and gaps, share resources, ology or Medicine for his role in discov- Next Pandemic Health Organization.” the frontlines to identify treatments and and work closely with provincial health ering the hepatitis C virus. Preparing for the next pandemic has Murthy added that many of the chal- improve care for COVID-19 patients. authorities. But like most other countries, our become a priority for Dr. Srinivas lenges in pandemic preparedness are “Before this pandemic arrived we had “The point of this was to coordi- response was not perfect. Houghton said Murthy. In July, the BC Children’s Hos- more about politics, policy, data privacy nobody working on coronavirus, but we nate all the research so everybody knew Canada needs better planning so that pital researcher was awarded a research and public engagement than the actual had a strong infrastructure for clinical what other people were doing to avoid when the next pandemic strikes – as chair by Innovative Medicines Canada science. Solving these challenges will trials that allowed us to implement the duplication and to establish collaboration it inevitably will – “we can respond to study Canada’s response to the current require better coordination, governance COVID-19 trials almost immediately,” across the province on similar areas of quicker and more independently”. COVID-19 crisis, and how our health and leadership. said Dr. Robert McMaster, currently research,” said McMaster. “COVID-19 is sending out the mes- system can do better when the next A pandemic preparedness plan would Vice Dean Research, Faculty of Med- sage: We need to boost funding for basic pandemic strikes. also make it possible to quickly scale up icine, University of British Columbia Continued on page 6

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and study all COVID-19 related The importance of collaboration fact-checking activities in part- nership with the World Health Organization. in an era of COVID-19 As Ryerson looks to the and health-care providers are focused on the considerable rip- development of this technique, Members of Ryerson Urban innovations of the future, a col- working side-by-side with com- ple effects of the pandemic. This which can be applied to other Water, led by Drs. Claire Oswald laboration with SOTI will boost mercial partners and academia, long-lasting and deep disruption diseases, is possible thanks to the and Kim Gilbride, are using the development of aerial drone backed by the support of public is certain to have far-reaching combined efforts of his research molecular tools and wastewater technology for medical services. institutions. implications for the everyday team, YYZ Pharmatech Inc., analysis to track the COVID-19 This could include the delivery At Ryerson, our scholarly, lives of Canadians and commu- National Taiwan University and virus in the sewage system in an of medical supplies, improving research and creative (SRC) nities worldwide. To truly con- St. Michael’s Hospital, a site of effort to establish an early warn- service to remote or rural areas Dr. Steven N. Liss Vice-President, Research and community has leveraged its front this pandemic, we must Unity Health Toronto. ing system of local outbreaks. In and limiting person-to-person Innovation strong partnerships and col- ensure that no one is left behind In recognition of the key role Toronto, they are working with contact when required. Ryerson University laborations across these areas. as we begin our recovery. of human connectedness in over- partners, including Toronto Pub- When emerging from the The bonds we have forged with Refining virus detection all wellness, Drs. Sepali Guruge lic Health, Public Health Ontario COVID-19 pandemic, col- hospitals, industry, municipali- methods is an important part and Lori Schindel Martin are illu- and Toronto Water. Supported laboration will remain at the he global fight against ties and other organizations have of containing the spread of dis- minating best practices in rela- by the Canadian Water Network, forefront of Canada’s recovery, COVID-19 has illus- enabled members of our SRC ease. Dr. John G. Marshall is tional care within long-term care they are contributing surveillance our future prosperity and our trated the essential enterprise to establish rapid developing a highly accurate homes during pandemics. Their data along with a number of other well-being. During these times, Trole that collabora- responses to the most key issues. COVID-19 test that can detect research team comprises experts university laboratories from loca- Ryerson will continue its focus tion plays in tackling complex Many of these challenges even the smallest trace of the from the Daphne Cockwell tions across Ontario and Canada. on both technologies and the global challenges. We have seen are immediate: diagnosing the virus in a patient sample. The School of Nursing at Ryerson, the To tackle misinformation social dimensions of the chal- researchers collaborate across disease, investigating drug treat- test uses Dr. Marshall’s ELiMSA University Health Network and surrounding the pandemic, lenges that we face, ensuring diverse fields to address the ments, monitoring the spread of technology, a platform that har- several Ontario universities and Dr. Anatoliy Gruzd and that solutions reflect our orien- direct and indirect effects of the the virus and innovating new nesses the power of the ultra- specialist organizations, includ- Philip Mai of the Ryerson Social tation to equity, innovation and crisis. Universities have com- personal protective equipment. sensitive and commonly avail- ing the Ontario Long-Term Care Media Lab are spearheading an healthy communities through- bined expertise across borders But our researchers are also able mass spectrometer. The Association. international effort to document out our country. researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 3 Canada’s TOP 50 RESEARCH C I UNIVERSITIES 2020 L Rank Sponsored Research Income Research Intensity

% Change $ per $ per Grad FY2019 FY2018 2018- Faculty Student 2019 2018 University $000 $000 2019 $000 $000 Tier* Prov

1 1 University of Toronto+ $1,089,287 $1,111,035 -2.0 $399.6 $56.5 M ON 2 2 University of British Columbia $624,465 $618,024 1.0 $262.8 $57.0 M BC 3 4 McGill University $606,489 $566,598 7.0 $336.8 $62.2 M QC 4 3 Université de Montréal $597,168 $567,065 5.3 $289.9 $36.3 M QC 5 5 University of Alberta $506,299 $493,824 2.5 $242.4 $64.2 M AB 6 6 University of Calgary $487,805 $421,761 15.7 $315.7 $77.8 M AB 7 7 Université Laval $401,441 $403,841 -0.6 $262.4 $37.3 M QC 8 8 McMaster University $371,599 $391,573 -5.1 $404.4 $75.1 M ON 9 9 University of Ottawa $346,406 $314,609 10.1 $273.6 $48.5 M ON 10 10 Western University $245,965 $260,740 -5.7 $160.2 $37.9 M ON 11 14 University of Saskatchewan $243,531 $175,057 39.1 $231.9 $71.9 M SK 12 11 University of Waterloo $240,726 $212,649 13.2 $201.6 $40.2 C ON 13 13 Queen’s University $235,231 $175,929 33.7 $294.8 $44.1 M ON 14 15 Université de Sherbrooke $169,319 $160,248 5.7 $141.9 $17.1 M QC 15 16 University of Guelph $164,591 $149,829 9.9 $198.5 $56.6 C ON 16 17 Simon Fraser University $160,988 $142,598 12.9 $182.3 $32.4 C BC 17 12 University of Manitoba $160,838 $212,295 -24.2 $134.0 $41.5 M MB 18 20 Memorial University of Newfoundland $160,636 $116,796 37.5 $170.0 $41.9 M NL 19 18 Dalhousie University $151,334 $141,311 7.1 $136.2 $41.5 M NS 20 19 University of Victoria $114,083 $118,599 -3.8 $155.0 $37.9 C BC 21 21 York University $100,304 $105,168 -4.6 $73.9 $16.8 C ON 22 23 Carleton University $81,760 $70,298 16.3 $98.7 $19.9 C ON 23 26 Ryerson University $79,574 $48,664 63.5 $95.2 $28.9 C ON 24 22 Université du Québec à Montréal $76,485 $70,947 7.8 $70.1 $9.7 C QC 25 24 Institut national de la recherche scientifique $71,889 $64,018 12.3 $482.5 $108.4 S QC 26 25 Concordia University $61,899 $55,999 10.5 $72.1 $8.7 C QC 27 28 University of New Brunswick $48,474 $38,694 25.3 $107.2 $30.3 C NB 28 27 Laurentian University $39,400 $44,013 -10.5 $99.0 $43.3 U ON 29 29 École de technologie supérieure $35,734 $30,165 18.5 $189.1 $18.5 S QC 30 31 Université du Québec à Rimouski $30,550 $25,262 20.9 $149.8 $27.6 U QC 31 30 University of Windsor $30,067 $28,207 6.6 $59.9 $7.4 C ON 32 34 Université du Québec à Trois-Rivières $29,298 $21,259 37.8 $63.4 $10.7 U QC 33 33 Université du Québec à Chicoutimi $25,257 $22,628 11.6 $100.6 $16.0 U QC 34 36 University of Regina $24,357 $18,927 28.7 $58.1 $12.8 U SK 35 32 Lakehead University $22,820 $23,975 -4.8 $65.8 $17.5 U ON 36 37 Wilfrid Laurier University $18,160 $18,877 -3.8 $34.2 $9.0 U ON 37 35 Université du Québec en Abitibi-Témiscamingue $17,539 $19,400 -9.6 $141.4 $24.3 U QC 38 38 Brock University $16,636 $15,735 5.7 $28.9 $9.4 U ON 39 41 Ontario Tech University $16,373 $11,908 37.5 $76.5 $20.2 U ON 40 39 University of Lethbridge $15,782 $15,165 4.1 $43.6 $26.8 U AB 41 44 Université de Moncton $12,946 $11,184 15.8 $38.1 $22.7 U NB 42 46 University of Northern British Columbia $12,943 $9,084 42.5 $66.0 $21.4 U BC 43 40 Royal Military College of Canada++ $12,567 $13,202 -4.8 $66.5 $37.5 U ON 44 45 University of Winnipeg $12,344 $9,419 31.1 $42.4 $50.4 U MB 45 42 Trent University $11,555 $11,430 1.1 $46.2 $18.0 U ON 46 48 Université du Québec en Outaouais $11,097 $7,863 41.1 $44.6 $7.6 U QC 47 43 University of Prince Edward Island $10,744 $11,363 -5.4 $40.7 $22.6 U PE 48 47 Saint Mary’s University $10,041 $8,502 18.1 $40.0 $15.3 U NS 49 50 Acadia University $7,347 $6,381 15.1 $38.5 $14.0 U NS 50 49 St. Francis Xavier University $7,335 $7,326 0.1 $30.1 $18.2 U NS

Notes: Education Commission, Ministère de l’Éducation et de l’Enseignement supérieur, Ontario 1. Sponsored research income includes all funds to support research received in the form Ministry of Advanced Education and Skills Development, Manitoba Advanced Learning of a grant, contribution or contract from all sources external to the institution. Division, Alberta Advanced Education, BC HEADSet and some individual universities. 2. Financial data were obtained from Statistics Canada, except where noted. 6. All data are provided for the main university including its affiliated institutions, where 3. Fiscal 2018 research income figures may have been adjusted as more accurate information applicable. became available. 7. All main institutions are members of the Canadian Association of University Business 4. Faculty headcounts for academic year 2018-2019 were used to calculate Research Officers (CAUBO). Intensity-$ per Faculty. Includes full and part-time: full, associate and assistant ranks as provided/available. Data were obtained from Research Infosource’s Canadian University *Tier: M - Medical, C - Comprehensive, U - Undergraduate, S - Specialized (not full-service) R&D Database. +Sponsored research income administered by affiliated hospitals was reported one fiscal year 5. Graduate student enrollment headcounts for academic year 2018-2019 were used to in arrears calculate Research Intensity-$ per Graduate Student. Includes full and part-time students ++Sponsored research income figures were obtained directly from the university enrolled in graduate level (master’s and doctorate) programs and courses leading to degrees, certificates or diplomas. Excludes students enrolled in health-related internships/residencies Research Infosource Inc. is Canada’s source of R&D intelligence. and first professional programs. Data were obtained from Maritime Provinces Higher For further information, please visit researchinfosource.com

Research Universities of the Year 2020

Three universities gain Research Infosource’s designation of Research University of the Year in their category for their performance on a balanced set of input and output measures. These full-service universities demonstrated superior performance on key measures of research success.

Rank Medical Score* Rank Comprehensive Score* Rank Undergraduate Score* 1 University of Toronto 97.0 1 University of Waterloo 97.0 1 University of Regina 80.8 Innovation 2 McGill University 70.1 2 University of Guelph 84.3 2 Lakehead University 74.9 Atlas Canada 3 McMaster University 68.4 3 Simon Fraser University 73.2 3 Université du Québec en Abitibi-Témiscamingue 74.9

innovationatlas.com *The score in each category is out of a possible 100 points based on the following measures and weighting: total sponsored research income (20%), research intensity per faculty (20%), research intensity per graduate student (10%), total number of publications in leading journals (20%), publication intensity (20%) and publication impact (10%). For each measure, the top ranking institution is assigned a score of 100 and the other institutions’ scores are calculated as a percentage of the first ranked institution. To be eligible to be included in the Research Universities of the Year Tier © Research Infosource Inc. 2021 rankings, full-service universities must have ranked in the top 50% in their respective tier for 5 out of 6 measures. Apparent ties due to rounding. See www.researchinfosource.com for details. Unauthorized reproduction prohibited. 4 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

CANADA’S TOP 50 Top Universities by Tier FY2019 Research Income Research Income Growth (% Change FY2018-FY2019) Rank Medical $000 Rank Medical % Research Universities 1 University of Toronto $1,089,287 1 University of Saskatchewan 39.1 2 University of British Columbia $624,465 2 Memorial University of Newfoundland 37.5 Research Income over Fiscal 2018. Eleven Comprehensive universi- 3 McGill University $606,489 3 Queen’s University 33.7 Growth Continues ties posted $1.16 billion of research income, a rise Tier Average (16) $399,863 Tier Average (16) 4.4 Research income at Canada’s Top 50 Research of 11.3%, and accounted for 14% of all university Rank Comprehensive $000 Rank Comprehensive % Universities advanced by 5.7% to $8.03 billion in research income. Twenty-one Undergraduate insti- 1 University of Waterloo $240,726 1 Ryerson University 63.5 Fiscal 2019, building on gains of 3.6% in Fiscal tutions reported a strong gain of 9.7% in research 2 University of Guelph $164,591 2 University of New Brunswick 25.3 2018 and 6.8% in Fiscal 2017. Research income income, to $365.1 million, which was 5% of the 3 Simon Fraser University $160,988 3 Carleton University 16.3 expanded at 37 universities and declined at 13 total, up from 4% in Fiscal 2018. Tier Average (11) $105,359 Tier Average (11) 11.3 others. In Fiscal 2019, average faculty research The top universities in each tier as measured by Rank Undergraduate $000 Rank Undergraduate % intensity – research income per faculty member – research income were: University of Toronto ($1.09 1 Laurentian University $39,400 1 University of Northern was $198,700, which was a solid increase of 5.0%. billion, 1st place overall), University of Waterloo 2 Université du Québec à Rimouski $30,550 British Columbia 42.5 Graduate student research intensity – research ($240.7 million, 12th overall), and Laurentian Uni- 3 Université du Québec à Trois-Rivières $29,298 2 Université du Québec en Outaouais 41.1 Tier Average (21) $17,385 income per graduate student – was $39,300, a rise versity ($39.4 million, 28th overall). 3 Université du Québec à Trois-Rivières 37.8 Tier Average (21) 9.7 of 2.7%. The Fiscal 2019 research income increase was Research Income Growth Faculty Research Intensity Graduate Student Research Intensity largely driven by Federal Government transfers. In Fiscal 2019, a range of universities reported ($ per Faculty) ($ per Graduate Student) Federal funding rose by 7.2% and accounted for research income growth that was well above Rank Medical $000 Rank Medical $000 46% of total university research income. Program the national rate of 5.7%. Top-place stand-outs 1 McMaster University $404.4 1 University of Calgary $77.8 funding through the Social Sciences and Humani- included University of Saskatchewan (Medi- 2 University of Toronto $399.6 2 McMaster University $75.1 3 McGill University $336.8 3 University of Saskatchewan $71.9 ties Research Council (up 11.2%), Natural Sciences cal, 39.1%), Ryerson University (Comprehen- Tier Average (16) $265.0 Tier Average (16) $49.2 and Engineering Research Council (up 10.4%) sive, 63.5%) and University of Northern British and Canada Research Chairs program (up 9.3%) Columbia (Undergraduate, 42.5%). Rank Comprehensive $000 Rank Comprehensive $000 were largely responsible for these gains. Provincial 1 University of Waterloo $201.6 1 University of Guelph $56.6 2 University of Guelph $198.5 2 University of Waterloo $40.2 Government funding increased by 4.1%. Corporate Faculty Research Intensity 3 Simon Fraser University $182.3 3 University of Victoria $37.9 research funding expanded by 4.0%. Although the Fiscal 2019 faculty research intensity – research Tier Average (11) $121.1 Tier Average (11) $23.0 sums are relatively small ($84.9 million), funding income per faculty position – was $198,700 overall, Rank Undergraduate $000 Rank Undergraduate $000 by Individuals was up by 122.9%. Foreign Govern- compared with $189,300 in Fiscal 2018. A number 1 Université du Québec à Rimouski $149.8 1 University of Winnipeg $50.4 ment funding ($140.4 million) rose by 12.9%. of universities had results that were well above the 2 Université du Québec en 2 Laurentian University $43.3 national average. Top-placed full-service universi- Abitibi-Témiscamingue $141.4 3 Royal Military College of Canada $37.5 The $100 Million Club ties by tier were: McMaster University ($404,400 3 Université du Québec à Chicoutimi $100.6 Tier Average (21) $17.1 Research Infosource inducted 21 universities with per faculty) in the Medical category, University of Tier Average (21) $57.5 over $100 million of research income into its Waterloo ($201,600) in the Comprehensive tier and Note: Based on full-service universities on the 2020 Top 50 Research Universities list. $100 Million Club. These leading institutions attract- in the Undergraduate group, Université du Québec ed a total of $7.18 billion of research income in à Rimouski ($149,800). Fiscal 2019, which accounted for 89% of all Medical tier, University of Guelph ($56,600) in Quebec’s 13 institutions garnered 27% of Top 50 Top 50 research income – a slight drop from 90% of Graduate Student the Comprehensive category and University of research income ($2.13 billion), unchanged from the total in Fiscal 2018. Research Intensity Winnipeg ($50,400) led the Undergraduate tier. Fiscal 2018. Three Alberta universities had 13% Graduate research intensity is a measure of the of research income ($1.0 billion), up from 12% of University Tiers amount of research income at each institution per Provincial Performance the total in Fiscal 2018. British Columbia’s four Sixteen Medical institutions posted a total of $6.40 graduate student. In Fiscal 2019, the top-ranked In Fiscal 2019, 18 Ontario universities attract- institutions attracted 11% of all research income billion of research income in Fiscal 2019, which full-service universities by tier were: University ed 39% of the national research income total ($912.5 million), down from 12% in Fiscal 2018. was 80% of the Top 50 total and an increase of 4.4% of Calgary ($77,800 per graduate student) in the ($3.12 billion), down from 40% in Fiscal 2018. Corporate and Not-for-Profit Corporate and Not-for-Profit Research Income by Tier FY2019 Research Income Corporate Research Income as Corporate Research Income Growth In Fiscal 2019, Top 50 Corporate research income Corporate Research Income % Total University Research Income (% Change FY2018-FY2019) accounted for $1.07 billion or 13% of total univer- Rank Medical $000 Rank Medical % Rank Medical % sity research income, down from 14% in Fiscal 1 McMaster University $123,694 1 Queen’s University 38.4 1 Queen’s University 90.9 2018. Not-for-Profit research income totalled $1.49 2 University of Toronto $113,418 2 McMaster University 33.3 2 University of Saskatchewan 48.3 3 Queen’s University $90,437 3 Memorial University of Newfoundland 31.2 3 Université Laval 47.1 billion, accounting for 19% of the total. Corporate Tier Average (16) $51,484 Tier Average (16) 12.9 Tier Average (16) 2.0 research income increased by 4.0% between Fiscal 2018 and Fiscal 2019 and Not-for-Profit by 1.5%. Rank Comprehensive $000 Rank Comprehensive % Rank Comprehensive % 1 University of Waterloo $26,634 1 University of Guelph 15.0 1 University of New Brunswick 54.0 2 University of Guelph $24,629 2 University of New Brunswick 12.5 2 University of Victoria 40.9 Research Universities 3 Université du Québec à Montréal $6,861 3 University of Waterloo 11.1 3 Carleton University 32.0 of the Year Tier Average (11) $7,918 Tier Average (11) 7.5 Tier Average (11) 9.6 Research Infosource has designated three institu- Rank Undergraduate $000 Rank Undergraduate % Rank Undergraduate % tions as Research Universities of the Year 2020 in 1 Université du Québec à Chicoutimi $6,201 1 Université du Québec en 1 Wilfrid Laurier University 656.6 their respective categories: University of Toronto 2 Université du Québec en Abitibi-Témiscamingue 32.3 2 Ontario Tech University 455.2 Abitibi-Témiscamingue $5,673 2 Ontario Tech University 24.8 3 Université du Québec à Rimouski 71.1 (Medical), University of Waterloo (Comprehensive) 3 Laurentian University $4,071 3 Université du Québec à Chicoutimi 24.6 Tier Average (21) 1.2 and University of Regina (Undergraduate). These Tier Average (21) $1,657 Tier Average (21) 9.5 institutions demonstrated superior performance on Not-for-Profit Research Income as Not-for-Profit Research Income Growth key measures of research success. Not-for-Profit Research Income % Total University Research Income (% Change FY2018-FY2019) Rank Medical $000 Rank Medical % Rank Medical % This Year and Next 1 University of Toronto $331,346 1 University of Manitoba 35.2 1 University of Saskatchewan 103.3 Fiscal 2019 saw strong gains in university research 2 Université de Montréal $105,600 2 University of Toronto 30.4 2 Université de Sherbrooke 30.1 income. Overall growth was 5.7% and almost three- 3 University of British Columbia $101,568 3 Université de Sherbrooke 20.9 3 Memorial University of Newfoundland 28.9 Tier Average (16) $71,283 Tier Average (16) 17.8 Tier Average (16) -1.0 quarters of universities grew their research income. Federal government support was particularly robust Rank Comprehensive $000 Rank Comprehensive % Rank Comprehensive % 1 University of Waterloo $25,676 1 University of New Brunswick 18.8 1 University of Guelph 141.6 and other funders were solid. 2 Simon Fraser University $22,377 2 Simon Fraser University 13.9 2 Concordia University 101.7 We expect that the Fiscal 2020 results will also 3 Université du Québec à Montréal $10,519 3 Université du Québec à Montréal 13.8 3 Ryerson University 55.0 be strong, due to the start of some recent emergency Tier Average (11) $10,067 Tier Average (11) 9.6 Tier Average (11) 7.6 funding for COVID-19-related matters flowing Rank Undergraduate $000 Rank Undergraduate % Rank Undergraduate % through the system, while there has been little 1 Lakehead University $5,598 1 Université de Moncton 38.7 1 University of Regina 98.5 or no diminution of other government funding. 2 Université de Moncton $5,011 2 Lakehead University 24.5 2 Université du Québec en 3 Université du Québec à 3 University of Prince Edward Island 17.4 Abitibi-Témiscamingue 88.7 COVID-19 is an important reminder of the neces- Trois-Rivières $3,085 Tier Average (19) 9.7 3 University of Lethbridge 85.8 sity of sustained investment in university research Tier Average (19) $1,761 Tier Average (19) 21.0 expertise and infrastructure that can be quickly Note: Based on full-service universities on the 2020 Top 50 Research Universities list, and reported research income from corporate and not-for-profit sources in the form of a grant or contract in Fiscal 2019. marshalled in times of national emergency.

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LEARN MORE AT DAL.CA/RESEARCH researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 5

Controlling COVID in long-term care

As COVID-19 continues to affect every aspect of life, Carleton University’s brightest minds are driving timely discoveries to keep people safe and combat the virus through world-class health and wellness research. For Industrial Design professor Chantal Trudel, that response involves protecting Canada’s most vulnerable population—long-term care residents. At the epicentre of the crisis, Trudel and her team are working to prevent and control outbreaks by designing safer and more efficient long-term care spaces. Chantal Trudel Associate Professor, Their research promises to help overburdened Industrial Design healthcare workers, protect residents—and Faculty of Engineering even save lives. It’s a shining example of and Design how innovative thinkers at Carleton, in every discipline, are advancing health and wellness as they tackle our current global emergency.

Explore more ground-breaking research. research.carleton.ca

YOU SEEK SOLUTIONS TO SHAPE THE FUTURE OF HEALTH

Discoveries in science and technology are revolutionizing human health with innovative solutions designed to speed diagnosis, increase treatment options, and help more people. As we face a global crisis together, University of Waterloo researchers continue to partner across disciplines to develop advanced medical devices and treatments, pharmaceutical and vision solutions, AI and quantum applications, and robotics to improve health and well-being.

Kelly Grindrod, Karim S. Karim, Ellen MacEachen, Professor, Professor, Faculty Professor, Faculty School of Pharmacy, of Engineering of Health Faculty of Science Executive Director Acting Director, Canadian Pharmacist of the Centre for School of Public of the Year Bioengineering Health and Health and Biotechnology Systems Kelly Grindrod uses research to help Canadian pharmacists keep up with the rapid A portable spectral X-ray technology developed Ellen MacEachen studies how work and health changes in public health, COVID-19 testing, by Waterloo spinoff KA Imaging was recently systems can adjust to changing economic, and vaccination. She developed an online approved by Health Canada and the U.S. Food social and technological environments. She tool, Pharmacy5in5, to help pharmacists, and Drug Administration, and is currently is leading a research team to identify disease technicians, and students stay up-to-date on in use for the early detection of lung cancer transmission risks embedded in low-wage ongoing trends in pharmacy and health care. and pneumonia including cases caused by employment practices and to develop tailored COVID-19. KA Imaging was founded by interventions to help contain COVID-19. Waterloo alumni Amol Karnick, Karim S. Karim, and Sina Ghanbarzadeh. FIND OUT MORE: uwaterloo.ca/news/home

Our greatest impact happens together. 6 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com LEADERS’ CORNER

It’s been a year like no other and the need for Lakehead University has a special relationship The University of Waterloo brings together world- evidence-based knowledge to inform citizens, with communities in Northwestern Ontario class academic strength, leading-edge research, influence decisions and drive change has never been and Simcoe County. Our catchment area is by experience-rich learning and a highly networked greater. Working with partners across disciplines, far the largest in Ontario, and populations that entrepreneurial culture that ignites curiosity and sectors and the globe, McMaster researchers are call Lakehead their university are extremely enables bold ventures. The Waterloo culture builds tackling the pandemic from every angle. I salute diverse. Community-Engaged Research is bridges between imagination and industry on a them – and the entire Canadian research community one of five Research Initiatives in our 2019- foundation of innovation that matters. – for their remarkable contributions. 2024 Research Plan. Our ranking as #1 in our Feridun Hamdullahpur Karen Mossman category in Not-for-Profit Research Income President and Vice-Chancellor Vice-President, Research reflects our commitment to knowledge University of Waterloo McMaster University mobilization in our regions. Andrew P. Dean, PhD Carleton University’s multidisciplinary research Vice-President, Research and Innovation At Sheridan, we’re proud to be a leader in strength in wellness provides tangible solutions to Lakehead University innovation, creativity and applied learning. alleviate the impact of COVID-19. From discoveries By fostering a collaborative culture of research, in mental and e-health, artificial intelligence and innovation and entrepreneurship, we create unique epidemiology, to a deeper understanding of impacts The relevance of the areas of intervention of opportunities for our faculty, staff and students on Indigenous communities and national economic our research centers is particularly pertinent in to work directly with industry and community concerns, we are taking a leadership role in a world where metal additive manufacturing partners to address real-world challenges to addressing these historic challenges. (3D printing), bio-based products, connected strengthen our communities. objects and sustainable development are at the Rafik Goubran Andrea England heart of our partners’ concerns. In addition, our Vice-President (Research and International) Vice Provost, Research research centers improve the academic career of Carleton University Sheridan College our students and allow professors to contribute to research and be at the forefront of advances Huawei Canada has been contributing to Canada’s in their discipline. At York University, we believe in the power accelerating knowledge economy for more than Louis Gendron of research to transform, and strive to make 12 years. For us, investing in Canadian R&D Chief Executive positive change. We bring expertise from across is a priority; it’s why we continue to focus on Cégep Trois-Rivières disciplines to build new tools and strategies creating jobs, developing talent, and contributing to tackle the complex societal challenges and to national GDP. We are proud to rank among historic crises we are currently facing – Canada’s top R&D investors. Through collaborations that support our research COVID-19 being paramount. Changtian Cai growth and potential to accelerate change, Dr. Amir Asif President Ryerson continues to leverage its scholarly, Vice-President Research & Innovation Huawei Canada R&D research and creative activities and the strength York University and breadth of our partnerships to address pressing societal issues. These very disruptions, once CMC lowers barriers to adoption of advanced The global pandemic has underlined the important anticipated for our future, are now at our doorstep. technologies in Canada. We maximize your research role of research and the need for Canadian Together with our partners, Ryerson is driving dollars through cost sharing and facilitation. laboratories and facilities to be ever-ready. innovation in critical areas such as health, We give Canada’s brightest minds the tools to Researchers across fields and across the nation community engagement and city building, and keep our economy on the bleeding edge through have been dedicated to overcoming the challenges advancing our digital future. simplified access to the best tools to design, we face. It is essential to continue providing them Dr. Steven N. Liss develop, and test ideas. these essential tools and facilities. Vice-President, Research and Innovation Gordon Harling Roseann O’Reilly Runte Ryerson University President and CEO President and CEO CMC Microsystems Canada Foundation for Innovation

KNOWLEDGE CHANGES EVERYTHING

UdeS accelerates research to solve complex societal problems requiring multidisciplinary approaches. This vision led to six unifying themes:

• Environment and Climate Change • Digital Age: Intelligent Organizations and Training • Innovative Materials / Processes and Quantum Science • Health: Promotion, Prevention, and Precision Approaches • Population Aging • Togetherness: Culture, Plurality, Governance and Equity

USherbrooke.ca/research

in clinical studies. A CL3 lab – also work because of our expertise in work- The third piece in a pandemic-fighting known as Biosafety Level 3 or BSL-3 – ing at the interface between human and arsenal is the ability to manufacture Society Under Threat is required to work with SARS-CoV-2. animal health,” said Dr. Volker Gerdts, enough vaccines domestically. VIDO is Continued from page 1 “More than 70% of emerging diseases Director and CEO of VIDO. “This allows currently building a pilot-scale manufac- are zoonotic in nature [an infectious us to work on both emerging diseases that turing plant, scheduled to open Septem- BC was able to quickly recruit Bridging Animal and disease that spreads from animals to are affecting animals as well as emerging ber 2021, with the capacity to produce patients for clinical trials using Human Diseases humans] so this R&D for pandemic pre- diseases that are affecting humans.” 20 million to 40 million vaccine doses a new online platform called One group working to build Canada’s paredness really underscores the impor- REACH BC where people register their capacity to respond rapidly to future tance of animal research – precisely the interest to participate in research. “Every pandemics is the Vaccine and Infectious type of critical research that has distin- More than 70% of emerging diseases are COVID-positive patient also receives Disease Organization at the University guished VIDO over its 45-year history,” zoonotic in nature so this R&D for pandemic preparedness a letter from Bonnie Henry (BC’s of Saskatchewan. VIDO was the first said Dr. Karen Chad, VP of Research at really underscores the importance of animal research Provincial Health Officer) asking if in Canada to isolate SARS-CoV-2 (the the University of Saskatchewan. “ DR. KAREN CHAD they want to participate in research,” virus that causes COVID-19), develop VIDO is now pitching the federal and Vice-President Research he said, adding that 73% of people an animal model, and get a vaccine provincial governments on a $60-mil- University of Saskatchewan contacted signed up. into preclinical (animal) testing. They lion plan to become Canada’s centre McMaster hopes to apply what have also been using their expertise to for pandemic research. This would The additional funds would also go annually for both animal and human tri- worked in responding to COVID-19 to help about 100 companies worldwide include upgrading part of their CL3 lab towards a new CL2 animal facility capa- als and potential emergency human use. other diseases. “The improved coor- develop therapeutics for COVID-19. to CL4, which meets the highest safety ble of housing exotic species such as Its first COVID-19 vaccine candidate, dination we’ve been able to accom- VIDO operates one of the world’s and security levels required to deal with bats, which can be vectors for emerging now undergoing Phase 1 safety trials in plish with COVID-19 research has largest containment level 3 (CL3) agri- the world’s most deadly viruses and diseases, and to recruit international sci- Halifax, is promising: as a subunit vac- been really amazing. I’ve never seen culture facilities designed to support pathogens, such as Ebola and smallpox. entists and fund new research chairs and cine it doesn’t require ultra-low freezer it before. Hopefully it’s paving the discovery research and pre-clinical tri- Canada’s only other level 4 lab is at fellowships. Having staff on site already temperatures, is fairly easy to make and way for how we will do things in the als using large and small animals. It the National Microbiology Laboratory trained to work in a high containment is cost-effective. future.” also has a 160-acre containment level in Winnipeg. environment can save months ramping 2 research facility for large animals used “VIDO is well-positioned to do this up when a pandemic strikes. Continued on page 14 researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 7

PARTNER PERSPECTIVE Positive changemaker York U contributes to Canada’s fight against COVID-19

ork is an exceptionally and the world around us for the Projects in Health, particularly on emergency pow- by filmmakers from Canada, diverse, research-inten- better. We bring expertise from Science & Engineering ers and restrictive public health Spain, South Africa, China and Ysive University commit- across many disciplines to build The Faculty of Science’s Jennifer measures. Germany. ted to enhancing the well-being new tools and strategies to tackle Chen, Cora Young and Trevor Vivian Saridakis (Faculty of Daniel Kikulwe, LA&PS, is of the communities it serves. the complex societal challenges VandenBoer are researching how Science) and Gillian E. Wu (Fac- leading an examination of how One AMPD project unites women “We strive to make positive and historic crises we are cur- to modify textiles and non-woven ulty of Health) are investigating Children’s Aid Societies across filmmakers from around the world in change,” says Vice-President rently facing – COVID-19 being materials to increase the protec- the idea that variations in the Ontario are adapting child protec- isolation during the pandemic Research & Innovation Amir paramount.” tion of personal protective equip- genomic sequences of the virus tion investigation safety interven- Asif. “We believe in the power of Embracing its role in aid- ment (PPE). may play a pivotal role in geo- tions, in the context of the pan- research to transform ourselves ing the world’s recovery from Marina Freire-Gormaly, Las- graphic differences in rates of demic, for immigrant and refugee pandemic. She is also examining COVID-19, in May 2020 York sonde School of Engineering, COVID-19 infection, transmis- families. implications for social inequality. awarded $300,000 in grants to is working with Faizul Mohee, sion and deaths. Jinyan Li and Scott Wilkie LA&PS’ Aaida Mamuji is advance new research projects director of research at TMB- (Osgoode Hall Law School) and leading a study on the risks and dedicated to Canada’s fight NEstradosinc, to explore how Projects in Social Science, Thaddeus Hwong (LA&PS) are benefits of contact tracing mea- against the pandemic. Research- COVID-19 is transmitted by Humanities, Education, evaluating Canadian government sures, and establishing a foun- ers submitted their proposals to a microdroplets that remain sus- Arts & Business support programs, their impact dation for developing guidance panel of scholars, and the projects pended in the air. Ingrid Veninger, School of the on the financial health of Canada mechanisms. started immediately after funding A.M. Viens, Faculty of Health; Arts, Media, Performance & and lessons from the COVID-19 Gertrude Mianda (Faculty of was announced. Adèle Cassola, Global Strategy Design (AMPD), led a proj- experience to assist in developing Graduate Studies) and Elaine Faculty of Science “The projects demonstrate Lab; Roojin Habibi and Steven ect that involves reaching out a fiscal antibody for future emer- Coburn (Glendon) are consider- “researchers are York’s ability to respond to the Hoffman, Osgoode Hall Law to women filmmakers around gency responses. ing how gender influences the studying how to unique challenges posed by the School; and Eric Kennedy, Facul- the world. The mandate of her The Faculty of Education’s challenges that measures, such pandemic,” says Asif. Detailed ty of Liberal Arts & Professional ONE(NINE) Project was to Sue Winton is researching how as social distancing, closure of increase the protection below, they also illustrate the Studies (LA&PS), are leading a make a film with whatever and teachers in two school districts, schools and travel restrictions, of cloth-based PPE extraordinary range of York’s team that’s mapping and evaluat- whomever you have with you in in Alberta and Ontario, enact pose to African immigrant men contribution. ing laws and policies, focusing isolation. Veninger was joined online learning policies during the and women. 21-OPR-173853 Canada’s Entrepreneurial University UCeed Access to infrastructure, mentorship, and capital for research- based ventures

Hunter Hub for Entrepreneurial Thinking Interdisciplinary nucleus that cultivates the next generation of entrepreneurial thinkers

University Innovation Quarter Research and innovation cluster with space for ventures to work alongside UCalgary researchers and students

Great research universities support great cities. Calgary is diverse, resilient, entrepreneurial, and will soon show the world that no matter what it throws at us, we are unstoppable.

ucalgary.ca/entrepreneurial

PARTNER PERSPECTIVE by developing potential new treat- COVID-19, McMaster research- ments such as new antibiotics, vac- ers – across all disciplines – have CANADA’S GLOBAL NEXUS: cines, and antibiotic alternatives. attracted more than $50M to • We’ve created the Centre fund more than 150 pandemic- of Excellence for Protective related research projects. These The power of partnerships Equipment and Materials – investments not only allow us to These are the world’s leading purpose: fight COVID-19, prevent And we’re making great strides. Canada’s first and only research respond to the crisis in the imme- researchers – in universities, hos- future pandemics and mitigate • Just weeks into the pandemic, hub dedicated to developing, diate and longer term, but they pitals, governments and industry global health risks such as antimi- researchers from the McMaster testing and validating personal are critical to our ability to train – and they’re doing incredible crobial resistance. Immunology Research Centre protective equipment. the next generation of leaders. work to battle COVID-19. Meeting the challenge of were part of the Canadian team • Under the guidance of the Much of this training will hap- If this virus has taught us any- infectious diseases and biological that isolated the virus. McMaster Health Forum, we’re pen at Canada’s Global Nexus for thing, it’s that collaborations are threats requires the integration of • Engineering and health home to the COVID-19 Evidence Pandemics and Biological Threats, David Farrar critical to solving global crises expertise across many disciplines researchers are working together Network to support Decision- where the world’s top experts will President and Vice-Chancellor and we simply cannot afford to and fields, ranging from virology, to create a viable new vaccine- makers (COVID-END) – an ini- converge, where industry leaders McMaster University allow these partnerships to end drug discovery, policymaking, delivery platform that does not tiative that brings together experts will work alongside academic and with this pandemic. and supply chain management rely on refrigeration, with the to collaborate and rapidly synthe- government researchers, where As Canada’s most research- to diagnostics, ethics, economics goal of getting life-saving vac- size the best available evidence ideas will be born, and discover- n a world and an environ- intensive university, we under- and beyond. cines to remote locations. across the full breadth of Canada’s ies made. It will be a world-class, ment where it’s easy to stand the power of partnerships. McMaster’s global leadership • Water researchers are ramping COVID-19 pandemic response. state-of-the-art research facility, Ibecome disconnected from That’s why McMaster has cre- in infectious disease research, up a wastewater testing program McMaster is recognized as an integral part of our national others, there is a critically impor- ated Canada’s Global Nexus our tradition of evidence-based designed to quickly detect and a trusted and reliable partner innovation ecosystem, and a vital tant group that has never been for Pandemics and Biological solutions, our world-class roster track COVID-19 in raw sewage nationally and internationally global resource. more connected. They’re work- Threats. of interdisciplinary experts, and which could serve as an early and we continue to attract more This isn’t our first pandemic ing around the clock and around Canada’s Global Nexus brings our network of partners from the warning sign for current out- corporate funding than any of and it’s not going to be our last. the globe, pooling their resources together an international network academy, industry, governments breaks and future pandemics. our peers. We’ve earned the con- It is critically important that we and talents, sharing their knowl- of scientists, clinical health and and not-for-profit agencies, posi- • Experts in the Michael G. fidence of the private sector and continue this momentum of part- edge and discoveries and creating medical specialists, engineers, tion us perfectly to drive the DeGroote Institute for Infec- governments alike, particularly nership building, that we use the dynamic and fruitful collabora- social scientists, history and pol- innovation needed to meet both tious Disease Research are look- when it comes to our pandemic- knowledge we’ve gained and our tions – all working for a common icy researchers, economics and current and future health crises ing for new ways to detect and related research expertise. collective expertise to be sure that purpose, and for the greater good. business experts with a shared head on. prevent antimicrobial resistance Since the emergence of we are fully prepared the next time. 8 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

How the drive to stop a virus mobilized Canada’s research community From producing face shields and hand sanitizer to monitoring wastewater and immune responses, Canadian researchers have become a critical front-line defence in fighting a global pandemic

By Debbie Lawes some labs, including designing and fab- “People used to think 3D printing is $75,000 in rapid response funding from ers investigating the potential for a com- ricating custom components to do the for printing parts,” added Maretzki. “But the Natural Sciences and Engineering mon blood thinner to prevent the need anada’s colleges, universities required testing. They were then able COVID-19 has forced us to think more Research Council, the team is reconfig- for intensive care for patients with severe and research hospitals are to test whether the locally designed and creatively about how these technologies uring the system to provide real-time, COVID-19, and experts in liver disease home to some of the most manufactured PPE met certification can be also used to respond to immediate vital signs monitoring of individuals who looking at how antiviral molecules can sophisticated expertise and standards. The team, which includes healthcare needs.” test positive for SARS-CoV-2, the virus help boost the body’s immune response C Dr. George Zahariadis from Memorial’s that causes COVID-19. The adapted sys- upon exposure to the SARS-CoV-2 virus. resources in the world. That’s why the Canadian government didn’t hesitate Faculty of Medicine and Dr. Kapil Tahlan Southern Ontario tem would keep patients connected to Another key example is the work of when the COVID-19 pandemic first from the Faculty of Science, is testing the Network For Advanced healthcare providers who can quickly tri- Dr. Eleanor Fish, Scientist Emeritus at started to invest a staggering $1.4 billion efficacy of sterilizing and re-using com- Manufacturing age and hospitalize those who may need the Toronto General Hospital Research on research to combat a disease that was mercially available medical masks against Innovation additional support. Institute. Her study, performed very threatening the lives and livelihoods of coronavirus-sized particles. The laryngoscope project was one of 31 millions of people worldwide. The pandemic has also given high priority COVID-19-related projects It wasn’t only governments that were Memorial a new perspective on the supported by the Niagara College-led This current study will help us to know exactly looking to the research community for potential for online learning. Like other Southern Ontario Network for Advanced how our older population is going to respond to vaccines and help. Early supply chain disruptions left educational institutions, much of its cur- Manufacturing Innovation (SONAMI). that helps us to make better policy decisions about how hospitals, companies and other organiza- riculum had to move online. What it The network of six colleges and “ protected or not to consider them as we go forward didn’t expect, however, was an unprec- McMaster University collaborates with tions scrambling to find personal protec- DR. LISA BARRETT tive equipment (PPE) such as gloves, edented spike in student admissions. small- and medium-sized enterprises Assistant Professor, Division of Infectious Diseases and Principal Investigator, masks, gowns and face shields to protect “Memorial’s enrolment went up in the (SMEs) to turn innovations into manu- Senescence, Aging, Infection and Immunity (SAIL) Laboratory staff, patients and customers. spring semester and then we saw our factured products. Companies have Dalhousie University Suddenly 3D printers were one of the highest enrolment ever in the fall from access to faculty, students and special- hottest commodities around. across Canada and international as well,” ized equipment and services, includ- “With this device, a frontline physician early in the pandemic with researchers said Bose. “It speaks to the strengths of ing automation, additive manufacturing, can monitor a patient wherever they are. If from Wuhan, China, found that a com- Cambrian College our programs and our research and shows process optimization, simulation and there are signs the person is running into monly used antiviral drug – interferon One academic who stepped up to help was that you don’t have to be in a major city modeling, information and communica- trouble the doctor can call them into the – can help speed up the recovery of Patrick Galipeau-Bélair. The mechanical to meet local needs or attract promising tions, technology and cybersecurity and hospital,” said Dr. Vicki Mowat, Director COVID-19 patients. engineer had joined Cambrian College’s students.” product testing and validation. of Research at Sheridan College. “This “Eleanor Fish is an infectious disease applied research department just two The Federal Economic Development will facilitate faster diagnosis and ongoing specialist and her study was related to months before the Sudbury campus was Niagara College Agency for Southern Ontario – which monitoring so people can get the hospital some of her early work on interferons closed in March 2020 in response to lock- Similar supply chain challenges were hap- has invested in SONAMI since 2016, help they need when they need it. The as an effective treatment for individuals down measures. Although most equip- pening across Canada, including in south- including a second contribution of $14 goal is to have this in the hands of health- with Ebola,” said Wouters. Fish is now ment was on campus and inaccessible, ern Ontario. Niagara College responded million announced in 2019 – approved care professionals this year.” participating in an international clinical Galipeau-Bélair had the foresight to take by collecting PPE from various depart- the network’s request to redirect six The Centre for Mobile Innovation is trial involving 300 families in Santiago, home three small desktop 3D printers. ments to donate to frontline workers. It months’ worth of its budget to pandemic- one of six research and incubation cen- Chile to determine whether the drug can Working from his garage, he began also retooled its Teaching Distillery – the related projects. The government agency tres at Sheridan. Mowat said this breadth stop the virus from spreading in people adapting open-source designs he found only one of its kind in Canada – from also agreed to waive the usual matching of research expertise enabled them to who are asymptomatic, offering a poten- online so he could batch print headbands making its small-batch artisan spirits to funding requirement, enabling SONAMI tackle a variety of pandemic-related chal- tially powerful new tool to reduce the for face masks using a smaller printer. producing a 70% alcohol disinfectant for to cover 100% of project costs, approxi- lenges. Another rapid-response project, spread of the virus in households. That ingenuity caught the attention of hand sanitizer and surface wipes. mately $750,000, during the first critical for example, is designing, testing and dis- Laurentian University which invited him Having manufacturing capacity on months of the pandemic. seminating creative interventions aimed Ryerson University to join a wider community effort to site created other opportunities to help. In “We were able to move very fast at at combating the online spread of misin- Ryerson University is one of several produce PPE for local hospitals and long- normal times, its Walker Advanced Man- this point,” said Sarah Dimick, Project formation about COVID-19, while a third research institutions across Canada work- term care homes. ufacturing Innovation Centre (WAMIC) Manager at SONAMI. “It opened the is focused on combatting food insecurity ing with provinces and municipalities on “I was able to make 600 in my garage. uses its expertise in engineering design, door for not just the SMEs, but also the amongst the elderly living on their own. an innovative way to catch COVID-19 One batch would make nine every four 3D laser scanning technologies, lean regional healthcare system, the family Mowat said she’s been impressed with outbreaks earlier – by sampling what’s hours, so I’d wake up early in the morn- manufacturing processes and addi- health teams to work with our network how fast research funding agencies have travelling down our toilets. ing, collect the prints from the night tive manufacturing to help companies and to mobilize on all of these urgent made grants available to colleges and A lot of different expertise comes before, hit print for the next one and develop working prototypes of promising needs.” universities during a public health emer- to bear on a project like this, includ- I’d get a yield of 27 per day on busier technologies. Academic institutions were also able gency. Application processes that typi- ing environmental biology, chemistry, days,” said Galipeau-Bélair, whose day WAMIC soon discovered that some of to launch projects quickly because strong cally take months were often reduced to geography, watersheds, civil engineering job usually involves designing and devel- these tools, notably its computer design relationships were in place with key local just a few weeks. “These are big govern- and computing modeling. This multi- oping equipment prototypes for industry, technology and laser-cutting machines, collaborators. ment, bureaucratic organizations but they disciplinary team of Ryerson research- including mining companies. could also be used to produce 500 face “If you don’t have the supply chain, were able to pivot quickly and redirect ers, led by Dr. Kimberley Gilbride and He said the experience has taught him shields a day for frontline health profes- the connections, and the planning already other sources of funds to create these Dr. Claire Oswald, is conducting tests two valuable lessons. One is how local sionals and other essential workers in in place when an emergency hits you’re new COVID-specific calls for research- in several Toronto neighbourhoods to businesses and community groups can the region. so far behind the eight ball it’s hard to ers. They’ve been amazing,” she said. discover how SARS-CoV-2 circulates come together quickly to address a global through municipal sewers. The technique supply chain challenge. University Health could be used to build an early warning The second? “If we are ever sent We have this huge research expertise and Network system for COVID-19, one that can iden- home again for something like this, I’m infrastructure studying all kinds of diseases and health A large amount of new basic and clinical tify the presence of a virus down to an not going to hesitate to put those printers conditions that could be deployed to address the research on COVID-19 is being con- individual building, even if those infected in the back of my truck and keep them in “ ducted at the University Health Network don’t have symptoms. most urgent questions in this brand new disease my garage on standby.” (UHN). The network of four Toronto “It just so happens that there’s DR. BRADLY WOUTERS Executive Vice President, Science and Research hospital sites has attracted $30 million to considerable link to shedding of the Memorial University of University Health Network date in new funding for more than 185 virus through the gastrointestinal track Newfoundland COVID-related research projects. (through feces) and hence the presence PPE shortages were also a problem in “We worked with Niagara Health to respond,” said Dimick. “Because our “That’s entirely due to the fact that of the virus in sewer waters and indica- Newfoundland and Labrador. In response, develop a face shield design that could network already existed and the funding we have this huge research expertise and tions of changes,” said Dr. Steven Liss, a group of local business leaders invited be made much faster than using a 3D was already in place, our members were infrastructure studying all kinds of dis- VP, Research and Innovation at Ryerson Memorial University to help design, fab- printer,” said Centre Manager Gordon able to execute all 31 projects in just over eases and all kinds of health conditions and one of the researchers on the study, ricate and test PPE as part of a new social Maretzki. “We had the resources and six months.” at all levels – from health services and which is being funded by the COVID-19 enterprise called TaskforceNL. The volun- were able to pivot to become a little For example, Conestoga College clinical research to fundamental discovery Immunity Task Force. teer group needed Memorial’s expertise, manufacturing facility. We ended up pro- received funding from SONAMI to – that could be deployed to address the “At the moment we’re sampling more including researchers and technical staff ducing over 37,000 face shields.” develop a mobile software application most urgent questions in this brand new at the system level, but you could sample from a variety of disciplines, to ensure Niagara College recently received to help critical supply chain workers disease,” said Dr. Bradly Wouters, UHN’s near where the wastewater discharges, that materials used for surgical face masks $50,000 from the Canada Foundation for maintain physical distancing, working Executive VP, Science and Research. including individual buildings such as and medical isolation gowns met Health Innovation to purchase a specialized 3D in partnership with a Kitchener-based As Canada’s largest research hospi- long-term care facilities, to identify the Canada’s strict safety standards. printer that can rapidly produce medical- cold-storage company. The new software tal, UHN was able to take an all-hands- prevalence and occurrence of the virus, as “TaskforceNL found that replacing ly safe materials for various PPE, includ- allows drivers to remain in their trucks on-deck approach to study this mysteri- well as emerging variants,” he explained. this supply wasn’t so easy because of ing face shields/masks, nasal swabs and and avoid face-to-face contact. ous disease. “Given that COVID-19 is Such a system could eventually be the testing and certifications required. a patient-administered saliva collector. “It’s touchless delivery. The driver a brand new disease, we, like the rest used to monitor other substances in Memorial wasn’t set up as a certified “These new printers have a vast pallet never has to interact with another person, of the world, had no ongoing COVID- wastewater, including other infections testing authority but we did have certain of biomedical materials which allows us and that protects your supply chain,” said related research; however, given our or emerging pathogens, as well as phar- expertise on the testing side, including to address more healthcare needs,” said Dimick. researchers’ broad expertise, we were maceuticals. It could even become an researchers and technical staff,” said Dr. Maretzki. “It also saves times in produc- able to leverage existing knowledge to early warning system for antibiotic Neil Bose, Memorial’s Vice-President tion by eliminating the machine tooling Sheridan College help tackle the disease from different resistance. (Research). The university moved quick- step so we can go straight to a medical Not all research is about inventing some- angles. For example, we had researchers “This is a wakeup call for Canada to ly to build this capability, making it device that can be put in the hands of the thing new. Often an existing product just studying interactions of cancer-related think about the wide variety of different among a handful of labs in the country healthcare practitioner.” needs some high-tech tweaking. That was proteins who used their unique technol- things that can be studied and analyzed initially able to do such testing. The new equipment will also enable the case with a low-cost and portable ogy platform to examine how COVID- from wastewater systems,” said Liss. One unexpected source of help came WAMIC to collaborate with McMaster diagnostic tool developed by design com- 19 proteins interact with our human “It also demonstrates how in times of from the university’s Hibernia Enhanced University and Hamilton Health Sciences pany Tech4Life, in collaboration with proteins, with important implications crisis, governments look to universities Oil Recovery Research Group, led by to develop a 3D-printed video laryngo- Sheridan’s Centre for Mobile Innovation. for discovering drugs that could disrupt to mobilize their research talent and process engineering professor Dr. Lesley scope sheath prototype that could be used The NewPneu device was initially those interactions,” said Wouters. research infrastructure in response to James. Her team worked to re-configure when COVID-19 patients need intubation. made for children with pneumonia. With UHN also has cardiovascular research- specific needs. researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 9

Dalhousie University facilities be changed to better protect Canada’s elderly have borne the brunt of both residents and staff? COVID-19 illness and death and Dr. Lisa This under-studied research question Barrett wants to know why. The infec- is one that Prof. Chantal Trudel and her tious disease specialist at Dalhousie Uni- team* at Carleton University’s School of versity is working with her colleagues Industrial Design are tackling in a project at the university and the Nova Scotia funded by the university and the Founda- Health, along with the Northwood long- tion for Health Environments Research term care facility in Halifax, to better in the US. understand immunity in elderly people. While infection prevention and con- Research Infosource is proud to be associated with Canada’s top innovators Northwood is Atlantic Canada’s largest trol protocols are well established for long-term care home and in early May hospitals and other healthcare settings, – in our universities, hospitals, colleges and companies – 2020 accounted for 87% of all corona- they can be a challenge in long-term who continue to step up during this global crisis. Individually and collectively, virus deaths in Nova Scotia. care, especially during a pandemic when they remind us of the value of our prior investments in research and innovation “We know very little about older protocols need to be developed and and the importance of linking our research capacity to those who can put it people’s immunity, why they get infec- deployed rapidly. to its best use. tions and die, particularly as it relates “The staff in these facilities are WE SALUTE AND THANK THEM ALL to COVID-19. That’s also important for already overworked and complying understanding how well, or not, a vac- with all the steps of infection prevention cine will work,” said Barrett, who leads and control protocols just adds to their Dalhousie’s Senescence Aging Infec- workload. That’s when we tend to see has responded with increased support homeless being included in pandemic Research teams will include medical tion and Immunity Lab, a team that errors happen,” said Trudel, whose team for urban areas to deal with the unique preparedness plans. She now wants to specialists, engineers, social scientists, includes research scientists, physicians is studying daily workflows to see if needs of this population, which typically see those efforts extended to rural and history and policy researchers, as well as and nurses. changes can reduce the burden. suffers from poor health, limited access remote areas. economics and business experts drawn The 350-person study is looking at Another complicating factor is that to nutritional food, and compromised “These communities face unique from across Canada and internationally. both natural immunity and vaccine- unlike hospitals, which are clinical in immune systems. challenges that need to be addressed “The network is a natural exten- induced immunity over about a 12-month nature, long-term care environments are But one group that continues to be in pandemic planning.” She added that sion of the work we’ve been doing in period. Previously, she studied how residents’ homes. “In a hospital setting overlooked are those who are home- more research is also needed to ensure the Michael G. DeGroote Institute for immune response to Cytomegalovirus – you don’t typically leave your patient less in rural and remote areas, includ- rural communities are better prepared. Infectious Disease Research which was a common virus that can infect people of room and go to a lounge to socialize. But ing Indigenous peoples who are over- “That’s the main goal because there started about 15 years ago. We already all ages – could affect a person’s suscep- that’s the daily living experience of long- represented in homeless populations. will be future waves of COVID-19 had a lot of those multidisciplinary and tibility to the HIV virus. term care residents.” It’s an issue that wasn’t even widely and other pandemics that follow in the multi-faculty collaborations in place,” “This current study will help us to The research is still ongoing but acknowledged until recently. future.” said McMaster’s VP Research Dr. Karen know exactly how our older population already Trudel sees potential solutions Evidence is now emerging showing Mossman, whose own lab studies how is going to respond to vaccines and that in how facilities are designed, structured that rural and remote communities experi- McMaster University viruses like SARS-CoV-2 evade host helps us to make better policy decisions and organized, including decentralizing ence homelessness rates equivalent to or Preventing future pandemics and miti- immune defenses. about how protected or not to consider core support areas like nursing stations. potentially higher than rates experienced gating global health threats like anti- Further fundraising is underway for a them as we go forward,” said Barrett, “This would limit the number of staff in urban areas, said Dr. Rebecca Schiff, microbial resistance is the mission of a new building to house Canada’s Global adding the trial results will also be appli- interactions,” she said. Associate Professor and Chair of Health new global initiative led by McMaster Nexus in a former glass warehouse at cable to other infections. The longer term and most effective Sciences at Lakehead University in Thun- University. The university’s leadership the McMaster Innovation Park in Ham- When not working on immunity solution, however, may appear the most der Bay. Yet these communities, which are in this area is recognized by the more ilton. It will include pharma-grade drug research, Barrett has been busy orga- expensive to governments: replacing already vulnerable to fewer healthcare and than $50 million McMaster researchers screening platforms, ambulatory clinical nizing pop-up testing sites in Halifax large institutional models of care devel- social service resources, have received have attracted already in research fund- space and expanded biosafety level 3 primarily aimed at testing asymptom- oped over 50 years ago with smaller little to no funding to help in caring for ing for some 150 COVID-19 related facilities capable of dealing with highly atic people who unknowingly spread the facilities. homeless people during the pandemic. research projects. contagious viruses like SARS-CoV-2. virus at home, work and the community. “There’s definite value in looking at So called “wicked problems” that “We recruited volunteers to run the these small home models but the ques- transcend national borders require testing events at places like, libraries, tion that is going to keep coming up Rural and remote communities face a global response that draws on the Lions Clubs and universities. It only is the finances to do this,” said Trudel. unique challenges that need to be addressed in world’s top experts across diverse sec- takes about 40 minutes to train someone “There is some evidence showing the pandemic planning … because they’re not funded in the tors and disciplines, including social to do a nasopharyngeal swab.” smaller home approach can lower costs, “ sciences like behavioural psychology same way as urban homelessness services The model is being replicated in the such as reduced use of medications and and economics, said Mossman. “A great United Kingdom and Barrett said it may reduced staff turnover. That evidence DR. REBECCA SCHIFF Associate Professor and Chair of Health Sciences example is around vaccine development be used for mass vaccinations in Nova is starting to come to light so it will be Lakehead University and distribution, which involves issues Scotia, recruiting people who already important to begin now to build the evi- like supply chains and vulnerable popu- know how to give an injection, including dence for de-institutionalization.” “Rural areas have a lot of challenges The university also received a lations. Also, how you get anti-vaxxers veterinary technicians. *Susan Braedley and Dennis Kao, School of Social just in providing any services to home- $2-million donation last year from and other people to understand and “What’s great about this model is that Work, Carleton University; Amy Hsu, Heidi Sveis- trup and Chantal Backman, Bruyère Research Insti- less people, including shelters, because philanthropist Stephen Jarislowsky to accept vaccines. You have to involve that is uses minimal health care resources and tute and University of Ottawa; Frank Knoefel, Sys- they’re not funded in the same way launch Canada’s Global Nexus for Pan- human element.” also increases community engagement, tems & Computer Engineering, Carleton University as urban homelessness services,” said demics and Biological Threats, a new “Our collaborative approach,” she which has helped to destigmatize test- and University of Ottawa; Sophie Orosz, Ontario Schiff. “If people don’t have a place network focused on developing inno- added, “has taught us that the best research Centres for Learning, Research and Innovation in ing,” said Barrett. “We believe it will also to go they’re more likely to be on the vative treatments and vaccines, novel results come from working together get more community buy in for getting Long-Term Care, Bruyère; Bruce Wallace, Systems & Computer Engineering, Carleton University and streets or be in places where they could diagnostics, data for informed policy- across disciplines and that’s exactly what vaccinated.” Bruyère Research Institute. raise the risk of transmission between making, epidemiological models and this will allow us to do both at McMaster others and between those who are not evidence-based plans and protocols to and with our global partners.” Carleton University Lakehead University homeless.” neutralize threats. Long-term care deaths have accounted The COVID-19 pandemic has taken its Schiff’s previous research on the A hallmark of the network will be its Debbie Lawes, Debbie@dovercourt- for nearly 80% of COVID-19 cases in greatest toll on the most vulnerable, effect that the H1N1 outbreak had on interdisciplinary approach to manage editorial.ca, is an Ottawa-based writer Canada, double the average of other including people who are homeless. Over homeless people in cities contributed the human and economic devastation of specializing in science, technology and countries. Could the design of these the past year, the federal government to policy changes that led to urban COVID-19 and avert future pandemics. innovation. RESEARCHERS’ CORNER

In March 2020, UCalgary assembled a panel Scientists at Baycrest’s Rotman Research Institute (RRI) of health and data experts to advise the are leveraging their expertise to understand and address the City of Calgary in their pandemic response. impacts of the COVID-19 pandemic on our brain health. Dr. Tyler Williamson led a team that created a Some RRI scientists, including those pictured on the right, data tracker powered by the Centre for Health are examining the effects of infection on brain structure Informatics, and we developed a matrix to help and function as part of a broad Canadian partnership. the City assess the impact of policy decisions. Others are looking at the toll of the pandemic on mental It’s our responsibility as scholars health and dementia risk in older adults. and community members to apply our Their work will help inform public health policy to Dr. Hude Quan Dr. Cathy Eastwood Dr. Tyler Williamson knowledge where it’s needed most. safeguard everyone’s health against COVID-19. Director, Operations Manager, Associate Director, Dr. William Ghali Centre for Health Centre for Health Centre for Health From top left, clockwise: Dr. Asaf Gilboa, Dr. Eugenie Roudaia, Informatics Informatics Informatics VP Research Dr. Allison Sekuler, Dr. Jean Chen University of Calgary

There has never been a greater need to collect real-time evidence to inform Those of us who work in infectious diseases know practice, policy and decision making during the COVID-19 pandemic. how important time is. The pandemic has shown us how A new study being led by Dr. Ingrid Waldron is helping to develop a culturally critical it is to move quickly to address biological threats specific COVID-19 response strategy to improve access to COVID-19 testing like COVID-19. And that’s what Canada’s Global Nexus and health services, and reduce infections among Nova Scotia’s historic has the opportunity to do – bring together partners from Black communities in order to better prepare for future emergencies. around the world, across an entire spectrum of Dr. Ingrid Waldron technologies, disciplines and expertise, to not only Associate Professor, School of Nursing solve this pandemic, but to prevent the next. Dalhousie University Gerry Wright Lead, Canada’s Global Nexus for Pandemics and Biological Threats McMaster University

In response to the urgent need for antiviral treatments, we are An essential part of R&D in identifying existing drugs that may Canada – especially while work against COVID-19. Maura R. Grossman Gordon V. Cormack facing the global pandemic of Our team, including Drs. Research Professor Professor COVID-19 – food safety and Roberto Botelho, Michael Olson, David R. Cheriton School of Computer Science, product development have University of Waterloo Sarah Sabatinos, Raffi Karshafian, continued at Niagara College Joe McPhee, postdoctoral fellow A new application of an artificial intelligence tool is helping under the leadership of Dr. Michael Sugiyama and partner to shave months off the time required to identify clinical Dr. Ana Cristina Vega Lugo, Cyclica Inc., is using artificial studies available to help physicians treat COVID-19 patients. Senior Food Scientist for intelligence to identify known Maura R. Grossman and Gordon V. Cormack, professors the CFWI Innovation Centre. drugs that may have new actions Photo: Sarah McIntyre in the School of Computer Science at the University of A sought-after judge for product against the virus. Waterloo, used a machine-learning approach to build the development challenges, and guest We’re also investigating the effectiveness of ultrasound AI-driven search tool to sift through thousands of new speaker for innovation and food Dr. Ana Cristina Vega Lugo and microbubbles therapy in impeding infection, in partnership COVID-19 studies quickly. The tool is being deployed in science conferences across Canada, Senior Food Scientist CFWI Innovation Centre with MD Precision. conjunction with the Knowledge Synthesis Team at Dr. Vega Lugo leads the team Dr. Costin N. Antonescu St. Michael’s Hospital on behalf of Health Canada. conducting applied research projects Associate Professor and technical services to benefit Department of Chemistry and Biology, Ryerson University many SMEs in this vital industry. 10 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

search to Re Re m su ro lt F s

I g n n n i o t a v r a b ti e on el Worth C

Canada’s innovation community ​continues to be at the forefront of research and discovery. ​

Through entrepreneurship, commercialization and social innovation, ​ researchers in our universities, hospitals, colleges and companies are​ turning ​their leading-edge research into products,​ technologies and services that advance our economy and improve​ the lives of citizens the world over.

​Take a look at how their work is transforming society. Sheridan’s Screen Industries Research and Training (SIRT) Centre is leading the acceleration of the future of content creation: Virtual Production. SIRT has developed a virtual pro- duction research centre within their 10,000 square-foot stage, at Pinewood Toronto Studios, along with a dedicated applied McMaster University’s Centre of Excellence in Protec- research team for Virtual Production innovation. With an array tive Equipment and Materials (CEPEM) is Canada’s first of technology partnerships including Epic Games (Unreal and only research hub dedicated to developing, testing and Engine), Nvidia, APG Media and ARRI, SIRT is able to validating personal protective equipment (PPE). Created at provide innovation support to content creators across Canada. the height of concerns about a possible PPE shortage for Over the last year, SIRT has worked closely with Pixomondo, Ontario’s healthcare and frontline workers, CEPEM’s team SPINVFX, The Other End and other VFX/Production part- of faculty and student engineers and clinicians have worked ners to innovate their virtual production workflow. Virtual with more than 50 Canadian companies to develop and production offers solutions to industry partners affected by the validate products, get them to market faster, and rethink the COVID-19 pandemic, utilizing the power of real-time video design of PPE for the next generation of frontline workers. As part of Canada’s Global Nexus for Pandemics and Biological game engines to deliver high-quality graphics and visuals to Threats, an international network launched by McMaster, Ryerson Researchers Predict Lung Disease screen and opening further avenues to pursue remote collabora- CEPEM researchers are working across disciplines and with with Machine Learning tion using these real-time tools. sirtcentre.com their industry partners to ensure the safety of frontline work- Researchers from the Quantitative Image Analysis in Medi- ers and the long-term sustainability and success of this new cine lab at Ryerson University have created an innovative new Canadian industry. way of assessing and predicting lung disease. Led by Canada Research Chair and physics professor Dr. Miranda Kirby, the lab has successfully tested a method of combining machine learning with medical imaging technology. The technique involves taking scans of patients’ lungs and then processing the images using computer algorithms to unlock hidden information about the health of the organs. As well as revealing the presence, location and severity of any underlying conditions, this information provides a quantitative measurement of disease. This enables the scientists to apply machine learning, which can identify which patients are most likely to require health-care services in the future. In research involving collaborators from across Canada, the interdisciplinary team showed that their imaging approach was more accurate at predicting hospitalization among smokers than clinical assessments or standard lung function measurements.

Red River College (RRC), Manitoba’s only polytechnic, is Rakesh Sahu (left) and Ravi Selvaganapathy outside McMaster’s Centre partnering with industry to lead the way in the province’s eco- of Excellence in Protective Equipment and Materials. nomic recovery from COVID-19. Our award-winning research enterprise is operating at full capacity, featuring three Technol- ogy Access Centres (TACs) that work with industry to promote sustainability, functionality, and innovation. Our TACs bolster Quantum computing has the potential to solve problems beyond the capabilities Manitoba’s economy by supporting three key areas of research of conventional supercomputers and could produce a revolution in biochemistry, and development: culinary research and food sciences, build- finance, cryptography, and AI. The power of quantum computers is at an inflection ing efficiency technology, and aerospace and manufacturing as point and the industry is going to experience a surge in performance in the coming well as the interfaces between them. years. By developing projects with partners that directly impact CMC is a member of Canada’s first IBM Q-Hub at Université de Sherbrooke, our community’s fallout from COVID-19 – such as Cancer- providing programming services on this platform – IBM’s most powerful – for aca- Care Manitoba in the production of new wheelbases for IV demic and industrial researchers. We also participate in the QSciTech-QuantumBC poles, and Harvest Manitoba on protein-rich dehydrated soup training program, allowing researchers to use this powerful machine to its fullest mixes for people in need – RRC is not only helping partners potential. grow the economy, but laying the groundwork for a thriving CMC also partnered with Xanadu, a Toronto-based photonic quantum com- community in the years to come. puter company, on the Xanadu Quantum Sandbox. CMC will help companies and For more information, visit rrc.ca/research researchers use Xanadu’s made-in-Canada quantum platform. As we do for microelectronics, photonics, nanomaterials, and other technologies, CMC fills gaps and facilitates research in the Canadian quantum ecosystem which will be strategically important for Canada. Photo: IBM Canada

FEB 2021_CdnInvLdrs_third_CMN2104_Research.qxp_ARTWORK 2021-01-27 2:26 PM Page 1

CANADIAN MUSEUM OF NATURE RESEARCH WITH GLOBAL IMPACT. APPROVED BY At the Canadian Museum of Nature, we are dedicated to conducting fundamental research — in the field and in the lab — that helps foresee coming change. From paleobiology, to mineralogy to studying our changing Arctic, our 56 research and collections experts collaborate and publish with leading researchers across the globe. In 2019, our science enabled 385 academic research papers from 42 countries around the world producing insights that will help 102283 / Canadian Museum of Nature

save the world through evidence, knowledge Febraury 25, 2021 Wednesday January 27, 2021 Wednesday Canada’s Innovation Leaders - Research InfoSourceCanada’s and inspiration. Discover our annual science CMN-21-04 Thirdpage = 9.5" x 6.5" review at: nature.ca/impact 4 colour process docket / client publication insertion date ad size colour ad number  le released

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CANADA Photo: Paul Sokoloff Creative: STCstorytellers.com researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 11

The discovery of insulin by the University of Toronto 100 years ago is for treating — and ultimately conquering — debilitating diseases, includ- one of the most significant advances in the history of medicine. ing diabetes. And our scientists, clinicians and global health experts are on On this illustrious foundation, U of T and its hospital partners built a the front lines of Canada’s response to the global pandemic. culture of discovery, innovation and collaboration that has revolutionized In the years and decades ahead, we will keep pushing the boundaries health care in Canada and globally. Our discovery of stem cells sparked of what’s possible, advancing the culture of ingenuity and collaboration the promising field of regenerative medicine. Deep learning, a game- that started a century ago. changing AI technique, further enabled the development of personalized, Where will the next 100 years take us? precision medicine. Our trailblazing genetic research opened new avenues insulin100.utoronto.ca

Communities and industries have been chal- Next Generation Manufacturing Canada (NGen), The industry-led non-profit that leads lenged to be innovative, adaptable and prudent Canada’s Advanced Manufacturing Supercluster is harnessing the country’s strengths in research, as they navigate through the COVID-19 pan- technology, workforce and manufacturing to pioneer better ways to build. Founded in 2017, demic. Lambton College is providing access to NGen has leveraged federal contributions of over $148 million to support 62 collaborative, expertise, infrastructure and funding to industry transformational advanced manu- and community to meet immediate public needs, facturing projects to generate a total adopt new processes and technologies, develop of $359 million in new innovation long term solutions and support the rebuilding of spending. NGen’s efforts to connect the economy. In response to urgent community the Canadian manufacturing and need, Lambton College’s Research & Innova- technology ecosystems has resulted tion department supported our community to in the ability to leverage significant address PPE shortages. Lambton worked closely private sector investment in these with service providers and industry to adapt projects at a rate of $1.42 for every new technologies and processes, allowing them dollar of Supercluster funding. Not to revise their product and delivery models – only are these collaborative proj- permitting them to sustain or pivot. We are in ects meeting demands of the pri- partnership developing long-term and complex solutions that will have global impact including vate sector and creating new jobs, testing and vaccine technologies. Moving forward we are focused on collaborating with key products and processes, but they are stakeholders in developing and implementing responsive economic, workforce, and training also delivering benefits to Canadians in the form of cleaner energy, more sustainable industrial development strategies and solutions. processes, more resilient supplies of food and medical products.

Since 2009, Cambrian R&D, the applied research The CCNB-INNOV, a network of three applied research centers, has established itself as the arm of Cambrian College, has been helping industry trusted partner of the Atlantic Canadian SMEs in their journey to innovate, whether they operate and community partners in Sudbury, Ont. innovate by in industrial manufacturing, agriculture, bioprocessing, or shipbuilding verticals. It has aggres- connecting them with our expert faculty and staff and sively pursued its mission of accelerating the adoption of technology in SMEs by expanding its student researchers. Drawing from the college’s range capacities in robotics, automa- of academic programs and suite of specialized equip- tion, welding, material testing, ment, Cambrian R&D tackles challenges in all sectors. and digital manufacturing over We are especially renowned for our mining inno- the last three years. vation projects. In 2019, Cambrian was awarded its One of the initiatives that led first Technology Access Centre (TAC), a specialized to a wide-scale success in the research hub, from the Natural Sciences and Engineer- metal fabrication industry was ing Research Council of Canada. offering solutions to thermal Cambrian’s Centre for Smart Mining is one of two stress and distortion in weld- in Canada with a focus on mining innovation. The ments. By acquiring one of its Centre demystifies new technologies in the mining kind welding simulation soft- sector by creating strategic R&D partnerships and ware and stress relief equip- access to specialized equipment. ment, CCNB-INNOV delivered novel solutions to increase the efficiency and performance of To learn more about Cambrian R&D and how our metal fabrication projects for companies across the country. The new capacity and track record Centre for Smart Mining can be your gateway to inno- have helped CCNB-INNOV establish itself among only handful of organizations with such vation, please visit cambriancollege.ca/rd. specialized expertise in Canada.

Openness and diversity are among Canada’s greatest strengths.

They have enabled Huawei Canada’s research and development to grow. We’ve created jobs, trained talent, accelerated the knowledge economy, and contributed $700 million to Canadian GDP. We have come a long way—and today, we are proud to be one of Canada’s largest corporate R&D investors.

Building a Fully Connected, Intelligent World 12 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

Igniting a Century of Discovery

The discovery of insulin at the University of Toronto 100 research is opening new avenues for treating—and years ago is one of the most significant advances in the ultimately conquering—debilitating diseases, including history of medicine. Few events have transformed the lives diabetes. Our deep pool of ideas, talent and expertise of so many people, so suddenly and profoundly. is strengthening Canada’s global leadership in bioscience, bioengineering and biomanufacturing—sectors critical On this illustrious foundation, U of T and its hospital and to post-pandemic recovery. industry partners built a culture of discovery, innovation and collaboration that continues to revolutionize health care. Where will the next 100 years take us? Our discovery of stem cells sparked the promising field of regenerative medicine. Deep learning, a game-changing AI technique, further enabled the development of To find out more about the future of health personalized, precision medicine. Our trailblazing genetic innovation visit: uoft.me/todays-research

FROM THE CEO’S DESK expertise and capacity related to inexpensive ventilators. Manage- humans; animal research is also rial science is crucial in quickly Lessons learned from COVID-19 proving crucial. developing robust supply chains. This experience confirms A third aspect is that academic Ron Freedman Twelve months ago few peo- their role is largely to respond to In the same time frame (2010- points that many in the research research capacity needs to be CEO ple had heard the term coronavi- requests for funding from indi- 2016) the granting agencies community have long and cor- linked to industrial capacity. At Research Infosource Inc. rus. Today it dominates the news. vidual researchers and research invested around $64.6 million in rectly argued. One is that we times of crisis knowledge that By one count, conducted through organizations. research related to topics more can never fully anticipate threats resides in universities, hospitals he COVID-19 crisis is the Innovation Atlas of Canada, Today, the number of coro- generally related to “pandem- from nature, so we need a criti- and colleges must be rapidly a timely, if unwelcome, only 17 university, hospital or navirus researchers and proj- ics”, or around $9.3 million per cal base of expertise and capacity deployed to companies able to Treminder of the impor- college researchers were explicit- ects is certainly in the hundreds year. Other related research was to address emerging challenges. provide practical, on-the-ground tance of ongoing investment in a ly funded to work on coronavirus and quite likely much greater. undoubtedly in excess of that. A second is that societal threats solution, be they new drugs, diag- nation’s science and technology research in Canada between 2010 Funding is now in the many of It was that investment in exper- such as COVID-19 require nostic tests or equipment. This capacity. From one perspective, and 2016. In that same time- millions. How were we able to tise and capacity that allowed responses from all fields of S&T, cannot happen at the last minute. humankind is in an ongoing battle frame a total of $6.1 million was make the shift so rapidly from a us to pivot to COVID-19-related not just the life and natural sci- Prior and ongoing relationships, with nature; for example, earth- directed to coronavirus research score of coronavirus researchers research. Each day we read of ences. Behavioural science, for both organizational and individu- quakes, storms, invasive species, by CIHR, NSERC, SSHRC and and projects to many times that? existing research that is being example, is proving to be of criti- al, are needed. and zoonotic diseases such as CFI combined (an average of The answer is that we consis- re-purposed to the COVID-19 cal importance in the pandemic. One way of viewing soci- COVID-19 are constant threats around $871,000 per year). That tently invested in related research challenge: prime among them, Mathematical modelling is a cor- ety’s investment in its scientific and ongoing reminders of our is not to criticize the granting expertise (personnel) and capac- old drugs being used for treating nerstone of our response. Engi- capacity is as an insurance policy need for diligence and a capac- agencies, for they had no better ity (infrastructure) that could be COVID-19. It is easy to forget neering capacity is proving vital to against unforeseen risk. ity to anticipate and respond to idea of what 2020 would hold rapidly re-purposed when the the investments that were made to treatment solutions, for example To read the full editorial, click here emerging challenges. than anyone else. And besides, COVID-19 challenge emerged. develop those drugs. And not just in developing and manufacturing

PARTNER PERSPECTIVE

Enhancing collaboration and diversity in research In the fight against COVID-19, Although COVID-19 clearly has had devastating impacts on soci- we must not forget the brain ety, it also has had some posi- tive and democratizing effects on Various neurological symptoms baseline and several months later, and stay-at-home orders also may RRI and the Centre for Addic- the way people approach research have been reported, including to detect whether brain symp- lead to social isolation, depres- tion and Mental Health (CAMH), and innovation. New systems have changes in smell and taste and toms are present and whether sion, and loneliness – all risk researchers are monitoring been created to facilitate sharing of “brain fog.” These symptoms they resolve or linger. Although it factors for dementia. changes in mental health and the critical data across institutions, and can continue long after the virus is too early to tell the whole story, Additionally, the more people incidence of psychiatric illness we have seen a spirit of increased Dr. Allison Sekuler is gone, raising the concern of COVID-19 clearly is impacting stay isolated inside, the less likely during the pandemic among older collaboration. Conferences and Sandra A. Rotman Chair in an increased likelihood of cogni- brain structure and function. they are to exercise and sleep adults in Toronto. They are also colloquia have become virtual, Cognitive Neuroscience & Vice- tive decline for individuals in Our findings will help address well, two key ingredients for brain examining resilience and coping making them globally accessible, President Research, Baycrest; the long term, and, in the worst immediate needs resulting from health. People who are socially behaviours, both of which sup- and exposing everyone to more Managing Director, Baycrest’s case, a potential COVID-related COVID-19, and prepare for its isolated are also less likely to try port mental health. diverse speakers and a greater Rotman Research Institute; dementia. longer-term impacts. Results also new things to challenge their cog- Another RRI study is inves- exchange of ideas. Many scien- Managing Director, Centre for will allow medical professionals nitive abilities. This is important, tigating possible effects of the tists, including those at the RRI, Aging + Brain Health Innovation Baycrest’s Rotman Research Institute (RRI) is a world leader to direct patients in need towards because the brain is like a muscle COVID-19 pandemic on demen- have increased online data col- in the study of aging and human treatments as early as possible. that we need to keep exercising. tia risk in seniors. Researchers are lection, giving them access to a s the population ages, brain function, advancing our The Centre for Aging + Brain having frequent virtual check-ins broader pool of participants and so does the incidence of understanding of the complexity Maintaining brain and Health Innovation (CABHI), pow- with healthy older adults living in leading to larger, more diverse AAlzheimer’s disease and of the human brain, and promot- mental health during ered by Baycrest, has supported the community to assess changes samples and research findings. related dementias. Over half a ing effective care and improved COVID-19 the development, spread, and scale in their mental health, exercise We also have seen the acceler- million Canadians currently live quality of life for older adults To manage their health and mini- of numerous community-based routines, cognitive function, and ated development and adoption of with dementia, and that number everywhere. This year, many mize the risk of dementia, older and commercial solutions to help socialization levels, as well as innovations to address care needs is expected to nearly double in RRI scientists have applied their adults typically are encouraged address these issues, but there is their exposure to COVID-19. for older adults, helping us move less than 15 years. Last year, expertise to the urgent issue of to be socially active, exercise, eat much more work to be done. These studies will provide more quickly from ideas to impact. this major public health crisis understanding COVID-19’s right, get proper sleep, and stay public health officials with criti- It is often said that we should was compounded by another: the effects on brain health. cognitively engaged. However, Supporting older adults cal information needed to adapt not let a good crisis go to waste, COVID-19 pandemic. Researchers at Baycrest’s RRI public health measures that pro- during the pandemic community-wide restrictions to and our hope is that these enhanced and Sunnybrook Health Sciences tect people from the virus have To help inform public health mitigate the impact of COVID- approaches to research and inno- Understanding COVID-19’s are conducting sensory, cogni- made most, if not all, of these policy and identify other ways to 19, while minimizing the effects vation will remain long after the impact on the brain tive, and clinical assessments, activities a challenge. support older adults during this on older adults’ brain health. pandemic, so that we can use our Although COVID-19 usually along with electroencephalogra- To avoid infection, older adults difficult time, RRI scientists are Study outcomes will help inno- learnings from this challenging is thought of as a respiratory phy (EEG) and magnetic reso- may make fewer trips to the gro- examining the indirect effects of vators create the next generation time to enhance the experience of illness, it is increasingly clear nance imaging (MRI) of the brain cery store, potentially impacting COVID-19 on this group’s brain of targeted solutions to support aging for all for years to come. it affects many of our body’s in recovered COVID-19 patients. their ability to maintain a brain- health. seniors’ health and well-being To learn more about research at systems, including the brain. Study participants are assessed at healthy diet. Physical distancing In a joint study by Baycrest’s during and beyond the pandemic. the RRI, visit baycrest.org/research. researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 13 Canada’s TOP 40 RESEARCH HOSPITALS 2020 Research C I Rank Research Spending Intensity % Researcher Hospital L Change $ per $ as % of Hospital/Hospital Network/ FY2019 FY2018 2018- Researcher Total Hospital Main Affiliated 2019 2018 Health Authority $000 $000 2019 $000 Spending Prov Research Centre(s)/Institute(s)

1 1 University Health Network $408,300 $362,800 12.5 $547.3 17.8 ON PM Cancer Centre, Krembil, TGHRI, (UHN) McEwen Institute, Techna, KITE@UHN, TIER@UHN 2 2 Hospital for Sick Children $254,093 $246,625 3.0 $760.8 27.8 ON SickKids Research Institute 3 4 McGill University Health $203,660 $181,259 12.4 $511.7 16.5 QC Research Institute of the MUHC Centre (MUHC) 4 3 Hamilton Health Sciences $184,739 $195,757 -5.6 $366.5 11.9 ON Population Health Research Institute, Thrombosis and Atherosclerosis Research Institute, Escarpment Cancer Research Institute 5 5 Vancouver Coastal Health $181,029 $162,226 11.6 $449.2 4.9 BC Vancouver Coastal Health Research Authority Institute, Providence Health Care Research Institute 6 7 Ottawa Hospital $145,703 $139,799 4.2 $393.8 10.0 ON Ottawa Hospital Research Institute, Ottawa Heart Institute Research Corporation 7 6 Provincial Health Services $136,167 $154,364 -11.8 $175.0 3.7 BC BC Cancer Agency/Research Centre, Authority BC Children’s Hospital Research Institute, Women’s Health Research Institute 8 8 London Health Sciences $118,796 $123,790 -4.0 $600.0 7.0 ON Lawson Health Research Institute Centre/St. Joseph’s Health Care London (a) 9 9 CHU de Québec $110,450 $101,627 8.7 $349.5 8.8 QC Centre de recherche du CHU de - Université Laval Québec - Université Laval 10 10 Sunnybrook Health $102,128 $92,647 10.2 $306.7 9.5 ON Sunnybrook Research Institute, Sciences Centre Sunnybrook Research Academy 11 11 Unity Health Toronto $86,724 $86,480 0.3 $407.2 7.0 ON Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Science 12 12 Sinai Health $85,084 $84,093 1.2 $680.7 13.7 ON Lunenfeld-Tanenbaum Research Institute, Bridgepoint Collaboratory for Research and Innovation 13 15 Centre for Addiction and $78,835 $72,377 8.9 $532.7 17.3 ON Campbell Family Mental Health Mental Health Research Institute, Krembil Centre for Neuroinformatics, Azrieli Centre for Neuro-Radiochemistry 14 14 Centre hospitalier de $77,546 $75,251 3.0 $155.1 5.7 QC Centre de recherche du CHUM l’Université de Montréal (CHUM) 15 13 CIUSSS de la Capitale-Nationale $76,755 $76,200 0.7 $259.3 5.2 QC CERVO, VITAM, CIRRIS, CRUJeF 16 16 Alberta Health Services $55,316 $54,410 1.7 $160.8 na AB Cross Cancer Institute, Stollery - Edmonton Zone Children’s Hospital, Univ. of Alberta Hospital, NACTRC 17 27 CIUSSS de l’Estrie - $55,277 $49,607 11.4 $145.1 3.7 QC Centre de recherche du CHUS, Centre Centre Hospitalier Universitaire de recherche sur le vieillissement, de Sherbrooke (CHUS) Institut universitaire de première ligne en santé et services sociaux 18 17 CIUSSS du Centre- $52,275 $52,791 -1.0 $237.6 5.8 QC Lady Davis Institute at the Jewish Ouest-de-l´île de Montréal General Hospital 19 19 CHU Sainte-Justine $44,655 $38,564 15.8 $214.7 9.3 QC Centre de recherche du CHU Sainte-Justine 20 18 Montreal Heart Institute $41,592 $46,415 -10.4 $442.5 19.6 QC Montreal Heart Institute Research Center 21 22 Institut universitaire de $35,565 $30,018 18.5 $494.0 12.3 QC Centre de recherche de l’Institut cardiologie et de pneumologie universitaire de cardiologie et de de Québec - Université Laval pneumologie de Québec - Université Laval 22 21 CIUSSS de $32,456 $32,424 0.1 $540.9 3.4 QC Douglas Hospital Research Centre l’Ouest-de-l’Île-de-Montréal 23 24 CIUSSS de $32,272 $27,725 16.4 $182.3 2.5 QC Centre de recherche de l’Hôpital l’Est-de-l’Île-de-Montréal Maisonneuve-Rosemont, Centre de recherche de l’Institut universitaire de santé mentale de Montréal 24 23 Alberta Health Services $29,060 $29,723 -2.2 $363.3 na AB Alberta Children’s Hospital, Foothills - Calgary Zone Medical Centre, Tom Baker Cancer Centre, CCCR 25 25 Children’s Hospital of $26,874 $24,235 10.9 $107.1 8.0 ON Children’s Hospital of Eastern Ontario Eastern Ontario Research Institute 26 29 Kingston Health Sciences Centre $24,842 $19,539 27.1 $65.7 4.3 ON Kingston General Health Research Institute 27 26 St. Joseph’s Healthcare Hamilton $24,519 $24,227 1.2 $137.0 4.0 ON Research Institute of St. Joe’s Hamilton, Firestone Institute for Respiratory Health, Michael G. DeGroote Centre for Medicinal Cannabis Research 28 28 Nova Scotia Health Authority $23,988 $22,553 6.4 $77.4 1.1 NS 29 30 CIUSSS du Centre- $22,653 $17,359 30.5 $105.4 1.4 QC Centre de recherche de l’Institut Sud-de-l’Île-de-Montréal universitaire de gériatrie de Montréal, Institut universitaire sur la réadaptation en déficience physique de Montréal, Institut universitaire sur les Innovation dépendances Atlas Canada 30 32 Baycrest $18,301 $15,456 18.4 $610.0 10.2 ON Rotman Research Institute 31 35 Women’s College Hospital $14,825 $13,044 13.7 $285.1 8.8 ON Women’s College Research Institute, innovationatlas.com Women’s College Hospital Institute for Health System Solutions and Virtual Care 32 37 The Royal $14,515 $12,389 17.2 $181.4 8.1 ON University of Ottawa Institute of Mental Health Research 33 36 Holland Bloorview Kids $13,475 $12,539 7.5 $673.8 13.7 ON Bloorview Research Institute Rehabilitation Hospital 34 33 IWK Health Centre $13,051 $13,838 -5.7 $118.6 4.5 NS Canadian Center for Vaccinology, Centre for Research in Family Health, MicroResearch International 35 34 St. Boniface Hospital $13,046 $13,535 -3.6 $372.7 3.6 MB Albrechtsen Research Centre, Asper Clinical Institute 36 Health Sciences Centre Winnipeg $11,701 $12,383 -5.5 $107.3 1.8 MB follow us on twitter 37 39 Hôpital Montfort $10,493 $9,902 6.0 $117.9 4.5 ON Institut du Savoir Montfort @R_Infosource 38 40 Bruyère $10,376 $8,264 25.6 $314.4 6.5 ON Bruyère Research Institute 39 38 Health Sciences North $10,317 $9,996 3.2 $107.5 2.0 ON Health Sciences North Research Institute Research Infosource Inc. 40 Horizon Health Network $6,266 $6,068 3.3 $58.0 0.5 NB Stan Cassidy Centre for Rehabilitation, is Canada’s source of New Brunswick Heart Centre, Canada R&D intelligence. East Spine Centre

Notes: 4. FY2018 figures may have been adjusted as more accurate information became available. For further information, 1. Data were obtained through a survey or from financial statements. Information for Ontario 5. Data are provided for the main hospital/health network/health authority including their please visit was coordinated in part through the Ontario Hospital Association (OHA). affiliated hospitals and research centres/institutes, where applicable. 2. Research spending includes all funds (direct and indirect) spent on all sources (internal and researchinfosource.com external) to support research. na = Not available 3. Researcher headcounts include full and part-time researchers, scientists, investigators and (a) Research spending amounts were combined as these hospitals have one research institute. © Research Infosource Inc. 2021 clinician-researchers with a faculty appointment who actively conducted research in Fiscal 2019. Unauthorized reproduction prohibited. 14 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com CANADA’S TOP 40 Research Hospitals Healthy Year for Top 40 – Leading Provinces Spotlight on Hospital Research Activity FY2019 Hospital Research Province % of Total Canada’s Top 40 Research Hospitals spent a total Ontario (19) 57 Top Researcher-Intensive Organizations of $2.89 billion on research in Fiscal 2019, which (Research Spending per Researcher) represented a solid 4.9% year-on-year rise. Among Quebec (12) 27 Rank Large $000 Rank Medium $000 Rank Small $000 the leading hospitals, hospital networks and health British Columbia (2) 11 authorities 31 organizations saw research spending 1 London Health Sciences 1 Hospital for Sick 1 Holland Bloorview Centre/St. Joseph’s Children $760.8 Kids Rehabilitation gains compared to nine where research spending Health Care London $600.0 Hospital $673.8 declined. The number of researchers in the sector Provincial Performance 2 Sinai Health $680.7 rose to 9,393 – an increase of 2.7%. Average spend- Nineteen health organizations in Ontario accounted 2 University Health 2 Baycrest $610.0 ing per researcher was $307,400 – a 2.1% increase. for 57% of Top 40 research spending ($1.63 bil- Network (UHN) $547.3 3 CIUSSS de l’Ouest- In Fiscal 2019, University Health Network once lion), which was a slight increase from 56% in de-l’Île-de-Montréal $540.9 3 Institut universitaire de 3 McGill University cardiologie et de again headed the national list with $408.3 mil- Fiscal 2018. Twelve health research performers in Quebec accounted for 27% of the Top 40 research Health Centre pneumologie de Québec - lion of research spending, a hefty 12.5% increase (MUHC) $511.7 Université Laval $494.0 over Fiscal 2018. Hospital for Sick Children spent spending total ($785.2 million), up from 26%. The $254.1 million, a rise of 3.0% and McGill Univer- two British Columbia organizations accounted for sity Health Centre was third nationally with $203.7 11% of the total ($317.2 million), down slightly Top Hospital-Intensive Organizations million of research spending, a gain of 12.4%. from 12% in Fiscal 2018. (Research Spending as % of Total Hospital Spending) Rank Large % Rank Medium % Rank Small % The $100 Million Club Research Spending Growth 1 University Health 1 Hospital for Sick 1 Montreal Heart Institute 19.6 Ten health organizations reported in excess of $100 In total, 15 organizations reported double-digit Network (UHN) 17.8 Children 27.8 million each of research spending in Fiscal 2019, increases in their research spending in Fiscal 2019. 2 Holland Bloorview up from nine organizations in Fiscal 2018. Joining Heading the list was CIUSSS du Centre-Sud-de- 2 McGill University 2 Centre for Addiction Kids Rehabilitation l’Île-de-Montréal, where research activity grew by Health Centre (MUHC) 16.5 and Mental Health 17.3 Hospital 13.7 the $100 Million Club this year was Sunnybrook 30.5%. Research spending growth was also strong Health Sciences Centre. Total research spending of 3 Hamilton Health 3 Sinai Health 13.7 3 Institut universitaire de this elite group totalled $1.85 billion, up 10.6% on at Kingston Health Sciences Centre (27.1%), Sciences 11.9 cardiologie et de the year, and representing 64% of the Top 40 total, Bruyère (25.6%), Institut universitaire de cardi- pneumologie de Québec - a larger share than the 61% reported in Fiscal 2018. ologie et de pneumologie de Québec - Université Université Laval 12.3 Laval (18.5%), Baycrest (18.4%) and The Royal Note: Hospital size tiers were based on Fiscal 2019 total hospital spending: The $100 Million Club (17.2%) Large = more than $1 billion; Medium = $400 million to $1 billion; Small = less than $400 million. Research Research Intensity 2019 Spending Top 10 Research Hospitals by Rank Hospital $000 A number of health research organizations stood spending comprised 17.8% of total hospital spend- Research Spending Growth 1 University Health Network out on a number of key measures in their respec- ing, Medium category Hospital for Sick Chil- (UHN) $408,300 tive size groupings. The leading researcher- dren (27.8%) and Small category Montreal Heart 2019 % Change 2 Hospital for Sick Children $254,093 intensive organization (research spend- Institute (19.6%) of total hospital spending. Rank Hospital 2018- 2019 3 McGill University Health ing per researcher) in the Large category was 1 CIUSSS du Centre-Sud-de- Centre (MUHC) $203,660 London Health Sciences/St. Joseph’s Health Care This Year and Next l’Île-de-Montréal 30.5 4 Hamilton Health Sciences $184,739 London, which spent an average of $600,000 per Fiscal 2019 was a strong year for health research 2 Kingston Health Sciences Centre 27.1 5 Vancouver Coastal Health researcher in Fiscal 2019. The leader in the Medi- spending. Total research spending by the Top 40 3 Bruyère 25.6 Authority $181,029 um category – and the highest research intensive organizations across the country rose by 4.9% to 4 Institut universitaire de cardiologie et de pneumologie 6 Ottawa Hospital $145,703 institution overall was Hospital for Sick Children $2.89 billion. And research spending increased at de Québec - Université Laval 18.5 7 Provincial Health Services which spent $760,800 per researcher. Holland 31 of 40 organizations. 5 Baycrest 18.4 Authority $136,167 Bloorview Kids Rehabilitation Hospital was the Fiscal 2020 presents a more clouded picture. 6 The Royal 17.2 8 London Health Sciences Centre/ leading Small performer with $673,800 research Many health research organizations are being St. Joseph’s Health Care London $118,796 7 CIUSSS de l’Est-de-l’Île-de- spending per researcher. affected by COVID-19 restrictions and that may Montréal 16.4 9 CHU de Québec - In Fiscal 2019, the top leaders for hospital have some bearing on the level of their research 8 CHU Sainte-Justine 15.8 Université Laval $110,450 research intensity – research spending as a percent activities. On the other hand, new emergency fund- 9 Women’s College Hospital 13.7 10 Sunnybrook Health Sciences ing for research will find its way into the system. Centre $102,128 of total hospital spending were: for the Large 10 University Health Network (UHN) 12.5 category University Health Network research It will be interesting to see which trends prevail.

PARTNER PERSPECTIVE follow us on twitter @R_Infosource CANADA’S LARGEST RESEARCH HOSPITAL University Health Network is mobilizing COVID-19 knowledge and treatments Research hospitals like UHN are part he hospitals where serious how this virus interacts with pro- of a dynamic ecosystem that has cases of COVID-19 are teins in cells thereby identifying allowed for an integrated response to the COVID-19 pandemic. Ttreated also serve as a potential targets for COVID-19 vital link between discovery, therapeutics. Drs. Billia, Angela Cheung and care, industry and public health • Through clinical trials, collaborators are now aligning policy. Drs. Jordan Feld and Eleanor Fish these efforts with the University of Canada’s largest research hos- are exploring the use of antivi- Toronto and SickKids to develop a pital, University Health Network rals (known as interferons) to shared biobank to house >500,000 (UHN), is one example. With treat COVID-19 symptoms, with biological samples. over one million square feet of promising results. • Dr. Amit Oza developed a research space, UHN is home • Dr. Beate Sander established a new standardized framework – to approximately 5,000 research data model to help hospitals with called UDEPLOY – to safely team members who publish resource planning, while provid- expedite early phase COVID- around 3,500 studies annually. ing important public health data 19 clinical trials. UHN researchers have applied for governments. By serving as a living labo- their unique expertise, talent and • Early in the pandemic, Drs. ratory – where approaches, infrastructure to improve our Shahid Husain and Phyllis Billia treatments and strategies are knowledge of and ability to treat – partnered with the McCain rigorously designed, tested and COVID-19: Genito-Urinary Biobank and deployed – research hospitals • By using the same technology Techna – established an in-house are helping us to understand he uses to study cancer proteins, COVID-19 biobank within the virus now, and plan for the Dr. Brian Raught characterized UHN Biospecimen Services. future.

who have already secured funding to do protective equipment that were in short possibly manage so we prioritized Society Under Threat research on live SARS-CoV-2 to safely supply at the time. projects that could have immedi- conduct studies on the virus, not only Having elite facilities and the scien- ate impact,” said the lab’s director, Continued from page 6 grown in cells but also following in vivo tific expertise on hand when a pandemic Dr. Scott Gray-Owen, a Professor of “If you really want to respond as “Designing and building a CL3 lab experimental infections,” said Behr, who is strikes speaks to the importance of sus- Molecular Genetics at U of T. quickly as possible you have to have all from scratch can take years. It’s much also the Founding Director of the McGill tained government funding for funda- One such product was a self-cleaning these capabilities, including manufactur- easier to take an existing functional CL3 International TB Centre. mental discovery research, added Behr. antimicrobial face mask developed by ing and trained staff, available in-house,” lab and switch microbes,” said Dr. Marcel By May 2020, the facility received “We can’t forget about basic science Quebec-based I3 BioMedical Inc., whose said Gerdts. “This would put Canada on Behr, a senior scientist in the Infectious its first batch of SARS-CoV-2 from labs because we will need to be even better patented technology is at the core of par with other countries in terms of our Diseases and Immunity in Global Health in Quebec, Winnipeg, and Toronto. This prepared when the next pandemic comes,” the company’s entire line of medical pandemic research preparedness.” Program at RI-MUHC. enabled scientists to launch three types of he stressed. “That’s why we have to con- products such as wound dressings, medi- sider this CL3 lab as not merely a reaction cal tapes, gloves, headwear, gowns and The Need for Safe and to this current pandemic but a reaction to other personal protective equipment sold Secure Labs We can’t forget about basic science the next.” globally. Demand for CL3 labs exploded across because we will need to be even better prepared Testing at the high-tech containment Canada as the pandemic hit. The when the next pandemic comes Helping Companies lab – the only such facility in Toronto – Research Institute of the McGill Univer- “ DR. MARCEL BEHR in Need showed that the novel coating deactivat- sity Health Centre (RI-MUHC) began Senior Scientist Like RI-MUHC, the CL3 lab In the ed 99% of the SARS-CoV-2 virus within preparing for this spike when the first Infectious Diseases and Immunity in Global Health Program Temerty Faculty of Medicine at the minutes, greatly reducing the risk that case of COVID-19 was reported in Research Institute of the McGill University Health Centre (RI-MUHC) University of Toronto also responded health-care workers could be exposed Quebec in February 2020. The engineer- quickly to support researchers from to the virus by touching and adjusting ing platforms at McGill’s two CL3 labs, To repurpose the lab from study- studies: modifying an immune response across Canada, including many in their masks. which were set up to study tuberculosis ing bacteria to a virus, researchers and to the infection (critical in vaccine devel- industry who needed a facility equipped The U of T lab proved critical in the (TB), needed to quickly pivot to a virus trainees needed a crash course in virol- opment), testing compounds to treat the to work safely with a new virus. first days of the pandemic. Because no one had ever seen before. ogy. They also needed more equip- virus, and developing tools for diagnostic “We’re a research facility, not a of the facility’s experience in work- It was the first time these labs had ment to support more research groups. testing, said Behr. validation lab, but there was a real ing with the SARS virus in 2003, been enlisted to help with a national McGill stepped up providing an ini- One early project at RI-MUHC ran need for us to step up. Several hun- it was one of the first CL3 labs in medical emergency. Already having safe tial $308,000, with another $1 million experiments to find out if SARS-CoV-2 dred companies reached out to us to Canada to receive government approval and secure facilities, and staff trained in coming in November from the Canada could be killed with ultraviolet light, validate a product, test their drug or to work with SARS-CoV-2. It then biosafety protocols, made the transition Foundation for Innovation. making it possible for healthcare work- test their new disinfectant or other easier. “This will allow dozens of investigators ers to reuse masks and other personal technology. It was more than we could Continued on page 18 researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 15 Canada’s TOP 50 RESEARCH C I COLLEGES L Sponsored 2020 Research Rank Research Income Researchers Intensity % Change 2018- $ per FY2019 FY2018 2018- 2019 Researcher Main Affiliated Research 2019 2018 College $000 $000 2019 # $000 Prov Centre(s)/Institute(s)

1 2 Cégep de Trois-Rivières $15,827 $10,514 50.5 102 $155.2 QC CMQ, Innofibre, C2T3 2 3 Lambton College $12,420 $10,263 21.0 138 $90.0 ON Bio-Industrial Process Research Centre, Lambton Manufacturing Innovation Centre 3 11 NAIT - Northern Alberta $11,754 $5,547 111.9 52 $226.0 AB Institute of Technology 4 7 Mohawk College $10,884 $7,641 42.4 153 $71.1 ON IDEAWORKS 5 14 Red River College $9,303 $5,100 82.4 66 $141.0 MB Vehicle Technology & Energy Centre (VTEC) 6 8 Humber College $8,471 $7,556 12.1 384 $22.1 ON Barrett Centre for Technology Innovation 7 17 Southern Alberta Institute $8,445 $4,712 79.2 52 $162.4 AB Centre for Energy Research in of Technology (SAIT) Clean Unconventional Technology Solutions (CERCUTS) 8 1 Niagara College $7,828 $11,185 -30.0 43 $182.0 ON Agriculture & Environmental Technologies Innovation Centre 9 9 British Columbia Institute $7,531 $6,003 25.5 120 $62.8 BC Centre for Applied Research and of Technology Innovation (CARI) 10 10 Cégep de La Pocatière $7,358 $5,893 24.9 99 $74.3 QC Solutions Novika, Biopterre, Optech 11 13 Cégep Édouard-Montpetit $7,243 $5,177 39.9 102 $71.0 QC Centre technologique en aérospatiale 12 4 Cégep de la Gaspésie et des Îles $7,058 $9,460 -25.4 174 $40.6 QC Merinov, Nergica, CIRADD 13 18 Cégep de Thetford $6,456 $4,442 45.3 55 $117.4 QC Coalia, Kemitek 14 19 Sheridan College $6,412 $4,216 52.1 164 $39.1 ON Centre for Advanced Manufacturing and Design Technologies 15 6 George Brown College $6,255 $8,084 -22.6 136 $46.0 ON FIRSt, Product Development Exchange, Fashion Exchange, Social Innovation Exchange 16 26 College of the North Atlantic $6,151 $2,611 135.6 102 $60.3 NL Centre for Innovative Mining Solutions (CIMS), Newfoundland and Labrador Workforce Innovation Centre 17 Cégep de Jonquière $4,712 $3,940 19.6 90 $52.4 QC CPA, ÉCOBES 18 12 Conestoga College $4,629 $5,319 -13.0 254 $18.2 ON SMART Centre, Schlegel Centre for Advancing Seniors Care 19 20 Centennial College $4,480 $3,897 15.0 86 $52.1 ON Wearable Interactive Mobile Technologies Access Centre / Aerospace Innovation 20 22 Nova Scotia Community College $4,451 $2,983 49.2 73 $61.0 NS SEATAC 21 21 Collège de Maisonneuve $4,442 $3,253 36.6 67 $66.3 QC Centre d’études des procédés chimiques du Québec 22 33 Seneca College $4,112 $2,047 100.9 113 $36.4 ON Data Analytics Research Centre (DARC) 23 30 Fleming College $4,000 $2,234 79.1 48 $83.3 ON Centre for Advancement of Water and Wastewater Technologies, Centre for Sustainable Municipalities 24 32 Cambrian College $3,933 $2,080 89.1 52 $75.6 ON Glencore Centre for Innovation & Centre for Smart Mining 25 25 Cégep de Shawinigan $3,796 $2,663 42.5 39 $97.3 QC Centre national en électrochimie et en technologies environnementales (CNETE) 26 47 Lethbridge College $3,538 $1,064 232.5 43 $82.3 AB Centre for Sustainable Food Production 27 40 Cégep de Saint-Jérôme $3,481 $1,545 125.3 65 $53.6 QC CDCQ, IVI 28 24 Collège communautaire du $3,466 $2,835 22.3 34 $101.9 NB CCNB-INNOV Network Nouveau-Brunswick 29 48 Aurora College $3,102 $1,043 197.4 24 $129.3 NT Aurora Research Institute 30 16 Cégep de Sept-Îles $2,965 $5,040 -41.2 24 $123.5 QC ITMI, INERGIA 31 31 Cégep de l’Abitibi- $2,873 $2,195 30.9 35 $82.1 QC Centre technologique des résidus Témiscamingue industriels 32 27 Collège d’Alma $2,742 $2,395 14.5 32 $85.7 QC Agrinova 33 43 Olds College $2,297 $1,470 56.3 32 $71.8 AB Olds College Centre for Innovation (OCCI) 34 37 Holland College $2,260 $1,607 40.6 34 $66.5 PE Canada’s Smartest Kitchen 35 Fanshawe College $2,087 $697 199.4 31 $67.3 ON Centre for Applied Research and Innovation in Biotechnology (CARIB) 36 44 Cégep Beauce-Appalaches $1,955 $1,390 40.6 12 $162.9 QC MECANIUM 37 15 Algonquin College $1,837 $5,084 -63.9 46 $39.9 ON Data Analytics Centre 38 41 Cégep de Rimouski $1,833 $1,523 20.4 38 $48.2 QC SEREX, Innovation maritime 39 49 Selkirk College $1,769 $900 96.6 24 $73.7 BC SGRC, RDI, ARIC 40 35 Saskatchewan Polytechnic $1,736 $1,824 -4.8 68 $25.5 SK Digital Integration Centre of Excellence (DICE) 41 Durham College $1,655 $540 206.5 48 $34.5 ON CCBI, The AI Hub, Centre for Cybersecurity Innovation, MRC Studio 42 42 La Cité $1,619 $1,503 7.7 19 $85.2 ON Centre d’accès à la technologie en bio-innovation (CAT-B) 43 38 Camosun College $1,463 $1,588 -7.9 22 $66.5 BC Camosun Technology Access Centre 44 Bow Valley College $1,437 $231 522.1 24 $59.9 AB 45 Cégep de Rivière-du-Loup $1,385 $221 526.7 11 $125.9 QC LLiO, GREB 46 Loyalist College $943 $330 185.8 17 $55.5 ON Applied Research Centre for Natural Products and Medical Cannabis 47 27 Cégep de Lévis-Lauzon $875 $2,395 -63.5 34 $25.7 QC Centre de robotique et de vision industrielles (CRVI), TransBIOTech (TBT) Innovation 48 36 College of New Caledonia $840 $1,625 -48.3 23 $36.5 BC CNC Research Forest Atlas Canada 49 Georgian College $770 $532 44.7 35 $22.0 ON Research and Innovation Department innovationatlas.com 50 St. Clair College $703 $212 231.6 23 $30.6 ON Ford Centre for Excellence in Manufacturing (FCEM)

Notes: 1. Data were obtained through a survey of publicly-funded colleges and from financial statements. 4. FY2018 figures may have been adjusted as more accurate information became available. 2. Sponsored research income includes all funds to support research received in the form of a 5. Data are provided for the main college including affiliated research centres/institutes, follow us on twitter grant, contribution or contract from all sources external to the institution. Excludes funds where applicable. @R_Infosource from technical service agreements and entrepreneurship operations/activities. 3. Researcher headcounts include full and part-time faculty, teachers, researchers and Research Infosource Inc. is Canada’s source of R&D intelligence. © Research Infosource Inc. 2021 technicians who conducted research in Fiscal 2019. For further information, please visit researchinfosource.com Unauthorized reproduction prohibited. 16 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

Spotlight on College Research Activity FY2019 CANADA’S TOP 50 Research Partnerships*

Rank Large # Rank Medium # Rank Small # 1 Humber College 321 1 Cégep de la Gaspésie 1 Collège d’Alma 183 Research Colleges 2 Lambton College 239 et des Îles 249 2 Cégep de La Pocatière 160 3 Sheridan College 230 2 Cégep de Trois-Rivières 239 3 Cégep de Shawinigan 77 College Research Income Average per-college provincial income was high- 3 Cégep Édouard-Montpetit 122 Reaches New Highs est in Manitoba, where Red River College reported The combined sponsored research income of the $9.3 million of sponsored research income, fol- Completed Research Projects* colleges and cégeps on Canada’s Top 50 Research lowed by Newfoundland, where College of the Rank Large # Rank Medium # Rank Small # Colleges List reached $227.6 million in Fiscal 2019. North Atlantic received $6.2 million. Among large 1 Algonquin College 347 1 Cégep de Trois-Rivières 183 1 Cégep de La Pocatière 118 Research income was in the form of research grants, provinces, receipts in Alberta averaged $5.5 mil- 2 Niagara College 262 2 Cégep de la Gaspésie 2 Collège d’Alma 72 contracts and contributions (cash and in-kind) from lion. Quebec cégeps received an average of $4.7 3 Sheridan College 165 et des Îles 176 3 Cégep de Shawinigan 33 3 Holland College 82 third parties. Government funding accounted for million and Ontario colleges garnered an average $154.8 million, or 68% of the total. Federal govern- of $4.6 million. British Columbia colleges attracted Paid Student Researchers** ment sources were responsible for the largest gov- $2.9 million per institution on average. ernment share (46%) while Provincial governments Rank Large # Rank Medium # Rank Small # contributed 21% to the Government total. Corporate Research Income Growth 1 Mohawk College 353 1 Cégep de Trois-Rivières 87 1 Cégep de La Pocatière 36 2 George Brown College 313 2 Cégep de Saint-Jérôme 49 2 Cégep de Rivière-du-Loup 32 contributors accounted for 27% of total funding, Many of the institutions on this year’s list reported triple-digit growth in sponsored research income. 3 Centennial College 286 3 Cégep de la Gaspésie 2 Cégep de Shawinigan 32 while Non-Corporate sources provided 4%. et des Îles 44 Heading this year’s Top 50 list was Cégep de Among the top gainers were Cégep de Rivière-du- Loup (526.7%), Bow Valley College (522.1%) and Trois-Rivières, which reported $15.8 million of spon- Industry Research Income+ sored research income in Fiscal 2019, a 50.5% Lethbridge College (232.5%). Rank Large $000 Rank Medium $000 Rank Small $000 increase over Fiscal 2018. Lambton College rode a 1 Mohawk College $5,036 1 Cégep de 1 Cégep de La 21.0% research income gain to $12.4 million and Research Intensity A number of colleges stood out in terms of fac- 2 Lambton College $4,631 Trois-Rivières $4,086 Pocatière $3,690 NAIT - Northern Alberta Institute of Technology rose 3 Humber College $3,563 2 Cégep Édouard- 2 Cégep de Thetford $2,072 ulty research intensity – research income per fac- to 3rd position with a 111.9% increase to $11.8 mil- Montpetit $2,896 3 Cégep Beauce- lion. Overall, 40 institutions posted research income ulty member. The top three were NAIT - Northern 3 Cégep de Saint-Jérôme $1,336 Appalaches $1,523 gains against 10 where research income declined. Alberta Institute of Technology ($226,000 per faculty), Niagara College ($182,000) and Cégep Industry Research Income+ as % of Total Research Income Beauce-Appalaches ($162,900). Provincial Performance Rank Large % Rank Medium % Rank Small % In Fiscal 2019, 18 Ontario colleges accounted 1 Conestoga College 56.8 1 Loyalist College 59.8 1 Cégep Beauce- for 36% of the Top 50 total ($83.0 million) and Research Partnerships 2 Seneca College 49.0 2 Cégep Édouard- Appalaches 77.9 16 Quebec cégeps accounted for 33% ($75.0 and Projects 3 Mohawk College 46.3 Montpetit 40.0 2 Cégep de La Pocatière 50.1 million). Alberta’s five colleges were responsible Measuring a college’s or cégep’s volume of 3 Cégep de Saint-Jérôme 38.4 3 Cégep de Thetford 32.1 for 12% of the national total ($27.5 million) and research partnerships and completed research proj- Notes: 1. College size tiers were based on Fiscal 2019 total college income: **Students that were involved in applied research projects that British Columbia’s four institutions contributed ects provides a good indication of its levels of Large = more than $100 million; Medium = $50 million to were paid for their work. + 5% ($11.6 million). activity and output. A number of institutions stood $100 million; Small = less than $50 million. Includes research income reported from industry sources in the *Research partnerships and completed research projects with form of a grant, contribution or contract. Excludes all funds from out on these measures. Among Large institutions, external organizations governed by formal written agreements. technical service agreements and entrepreneurship operations/ Humber College led reporting 321 research part- Excludes technical services agreements. activities. Top 50 – Leading Provinces nerships in Fiscal 2019. Cégep de la Gaspésie Province % of Total et des Îles managed 249 partnerships to lead the projects. In Fiscal 2019, leaders in each category funding to remain stable, there is some uncertainty Ontario (18) 36 Medium category, while Collège d’Alma headed included Mohawk College (Large, $5.0 million around Corporate support. Nevertheless, Fiscal 2019 Quebec (16) 33 the Small tier with 183 partnerships. of industry income), Cégep de Trois Rivières establishes a strong base for future activity. Alberta (5) 12 In terms of completed research projects the lead- (Medium, $4.1 million) and Cégep de La Pocatière British Columbia (4) 5 ers by tier were: Algonquin led the Large tier with (Small, $3.7 million). 347 projects. Cégep de Trois Rivières in the Medi- Industry research income comprised a high Top 10 Research Colleges by um tier completed 183 projects and Cégep de La proportion of total sponsored research income Research Intensity Top 10 Research Colleges by Pocatière in the Small tier completed 118 projects. at a number of institutions. Industry income was Research Spending Growth $ per Students provide a large element of the col- highest at Conestoga College (Large, 56.8% of 2019 Researcher 2019 % Change lege research workforce and receive experience the total), Loyalist College (Medium, 59.8%) and Rank College $000 Rank College 2018- 2019 and payment in return. The top institutions by tier Cégep Beauce-Appalaches (Small, 77.9%). 1 NAIT - Northern Alberta 1 Cégep de Rivière-du-Loup 526.7 were: Mohawk College in the Large tier employed Institute of Technology $226.0 2 Bow Valley College 522.1 a total of 353 students on its research projects, This Year and Next 2 Niagara College $182.0 3 Lethbridge College 232.5 while Cégep de Trois Rivières in the Medium tier Fiscal 2019 was a solid year for Canada`s Top 50 3 Cégep Beauce-Appalaches $162.9 4 St. Clair College 231.6 employed 87 and Cégep de La Pocatière in the Research Colleges. Combined sponsored research 4 Southern Alberta Institute of Technology (SAIT) $162.4 5 Durham College 206.5 Small category hired 36. income topped $227 million and research income 5 Cégep de Trois-Rivières $155.2 6 Fanshawe College 199.4 increased at 80% of the institutions. Colleges and 6 Red River College $141.0 7 Aurora College 197.4 Industry Research Income cégeps forged thousands of research partnerships 7 Aurora College $129.3 8 Loyalist College 185.8 A key role of colleges and cégeps is to support and completed thousands of research projects. 8 Cégep de Rivière-du-Loup $125.9 9 College of the North Atlantic 135.6 firm-level innovation. A number of institutions It will be interesting to see what effect, if any, 9 Cégep de Sept-Îles $123.5 stood out in terms of the research income they the COVID-19 crisis has on college research activi- 10 Cégep de Saint-Jérôme 125.3 10 Cégep de Thetford $117.4 received from industry sources to work on research ties in Fiscal 2020. While we expect Government

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Collaborate with Sheridan on research and entrepreneurship RESEARCH opportunities that impact the communities we serve. We provide specialized expertise, talent and solutions to the challenges facing your business or sector. IN ACTION. #3 for research partnerships* #3 for completed research projects* INNOVATION #4 for number of student researchers*

AT WORK. research.sheridancollege.ca

* Based on FY 2019 numbers, published in CANADA S TOP Canada’s Top 50 Research Colleges 2020. RESEARCH50 COLLEGES

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In collaboration with Food HELPING COMMUNITIES PROSPER for Life and Community Devel- opment Halton, the CER team, led by Principal Investigator Dr. Leigh Hayden, with co-inves- beyond the pandemic tigator Dr. Sara Cumming from Sheridan’s Faculty of Humanities The effects of the COVID-19 EDGE: Entrepreneurship Hub and term care homes. And recently, and Social Sciences, have con- pandemic are leading to a myriad the Screen Industries Research and through a partnership with nected with, and are supporting, of changes, from small social Training Centre (SIRT) – mobi- Coca-Cola Canada, the CAMDT older adults to help meet their adjustments to global shifts. lized quickly to respond to the team built protective counter- nutritional and health needs. Photo provided by Coca Cola Canada As the world continues to emerging, real-world challenges top shields for small businesses Going forward, Hayden and her CAMDT Technologist Ramzy Ganady fabricating a protective countertop shield for small businesses. change, Sheridan has had to facing their communities. across Ontario. colleagues are working to part- change too, focusing its efforts on “Principal investigators, stu- Sheridan was also the proud ner with other organizations to dubious information. This will be By reconfiguring NewPneu, an re-imaging the way it works with dents, staff and funders adapted recipient of three Applied address lingering food insecu- translated into creative messag- existing mobile health system students, industry, and partners. their research work quickly and Research Rapid Response to rity, and other ongoing COVID- ing that will be distributed wide- initially designed to assist in Through the delivery of purpose- effectively in unprecedented COVID-19 research grants from related needs. ly, with the intent of reducing the pneumonia assessment in chil- ful research – a cornerstone of the circumstances,” says Andrea the Natural Sciences and Engi- In Sheridan’s Faculty of Hum- amount of misinformation being dren, this new system provides college – Sheridan has responded England, Vice Provost, Research neering Research Council of anities and Social Sciences, pro- shared online. Ultimately, this real-time vital signs monitoring to and anticipated the emerging at Sheridan. “Sheridan’s research Canada’s (NSERC) College and fessors Dr. Michael McNamara research will “nudge” Canadi- of individuals who test positive needs of its surrounding commu- and incubation centres have a Community Innovation Program. and Dr. Nathaniel Barr are tack- ans to think more deeply about for COVID-19. nities, developing new approaches wealth of experience in address- Recognizing that a large pro- ling the spread of misinformation the information they consume in Spurred on by the momen- for everyone’s benefit. ing industry and community portion of older adults had not online about the cause, scope and relation to the pandemic. tum of these and other initia- At the onset of the COVID-19 problems, and together, they ral- left their homes in months as treatment of COVID-19. Researchers and faculty from tives, Sheridan’s research eco- pandemic, Sheridan’s six Research lied to respond to the challenges a result of taking extra pre- In collaboration with Media- Sheridan’s Centre for Mobile system continues to grow, and Incubation Centres – the that the pandemic has brought to cautions to protect themselves Smarts, BEworks, and some of Innovation and the Faculty of thrive and diversify. In finding Canadian Music Theatre Project the fore.” against COVID-19, Sheridan’s the world’s foremost misinforma- Applied Science and Technol- creative approaches to address (CMTP), the Centre for Advanced Early on, Sheridan’s CAMDT Centre for Elder Research tion researchers, the project will ogy partnered with Canadian COVID-19 challenges through Manufacturing and Design Tech- team pivoted its efforts to address embarked on an initiative aimed see the development of insights research and design company research, Sheridan is dedicated nologies (CAMDT), the Centre for supply chain shortages, fabricat- at addressing food security from behavioural science and Tech4Life to develop a point-of- to strengthening and supporting Elder Research (CER), the Cen- ing face shields for health care among isolated older adults in digital/media literacy research care self-assessment and moni- its communities both during and tre for Mobile Innovation (CMI), workers at hospitals and long- the Halton Region. on how to stop the sharing of toring system for COVID-19. beyond the pandemic.

PARTNER PERSPECTIVE

of COVID-19, improved personal Alliance-COVID-19 initiative, we protective equipment, and more are also thinking about the success Flexibility and collaboration key to robust diagnostics. of this program in terms of the This initiative, of course, is longer-term benefits it brings to part of the federal government’s Canada’s R&D ecosystem. Using NSERC’s COVID-19 partnership grants overall response to the COVID- the new tools and ways of doing 19 crisis. But in particular, it is business that we implemented intended to leverage our resourc- prior to the pandemic, we had the ness. Those changes proved to As with most granting bod- NSERC decided to invest close es and networks to bring Cana- flexibility and agility to respond to be exceptionally useful when the ies, applicants submit detailed to $20 million in grants to address da’s broader research expertise the highly dynamic scientific and COVID-19 pandemic struck in proposals, which are evaluated the COVID-19 pandemic through into the fight against COVID-19, research challenges posed by this early 2020, and allowed NSERC and peer-reviewed. But to better the Alliance COVID-19 grants as and in particular disciplines like global crisis. to play a significant role in mobi- mobilize Canada’s research com- well as the College COVID-19 mathematics and engineering – Like all Canadians, NSERC’s lizing Canadian researchers and munity, we simplified the pro- grants, with the awards in both what we call the “all science” dedicated staff and our net- partner organizations in the drive gram and the applications proce- categories covering 100% of the approach. work of scientific advisors and to advance Canada’s capacity to dures in order to get the funding proposal. These grants went to proj- peer-reviewers have learned a respond to the coronavirus. into the hands of researchers and NSERC approved 317 Alli- ects relating to initiatives such great deal since March, 2020. Put simply, we were able to their partner organizations in a ance COVID-19 grants involv- as improved point-of-care testing We fully intend to capture and leverage the knowledge we’ve much more timely way. ing 387 partner organizations and technologies, ventilator design, embed these insights into our developed through years of fun- For COVID-19, we contin- 311 private sector collaborators, modular construction approaches own processes going forward. Alejandro Adem damental research in support- ued to receive applications, worth almost $15.7 million. On for rapid expansion of hospital The future will bring new President, Natural Sciences and ing industry and other groups to but added another option in the college side, NSERC hand- facilities and artificial intelligence challenges and other far-reach- Engineering Research Council of Canada bring science and engineering to response to rapidly evolving ed out 52 awards, totaling $3.8 solutions for infrastructure resil- ing societal crises (e.g., climate the fight. industry challenges. Using a million, with 93 organizations – ience during lockdowns. Partners change disruption) that will Since its inception almost two challenge process, researchers private, not-for-profit and public include pharmaceutical and engi- demand the full engagement of n April, 2019, the Natural years ago, NSERC’s Alliance were invited to submit pro- sector – involved. neering companies to research Canada’s outstanding scientific Sciences and Engineering grants have provided millions of posals, including those of a Behind these raw figures are centres of excellence, provincial community. Our experience of Research Council of Canada dollars to collaborative projects multi-disciplinary nature, and impressive scientific advances in health authorities, hospitals and the past year has shown that I(NSERC) adapted one of its involving researchers working we requested that they focus research on vital matters of public industry umbrella organizations. NSERC, through its Alliance core granting streams to improve with public, private, and not-for on core themes and problems health and safety, such as waste- Beyond the social and sci- program, is well positioned to the program’s agility and nimble- profit partners. related to the outbreak. water monitoring for the presence entific dividends of NSERC’s respond. 18 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

PARTNER PERSPECTIVE Humber College and Innovation 360 collaborate to help organizations be innovation ready founded by Magnus Penker, is from Innovation 360’s AI plat- said Ginger Grant, Dean of with partner organizations that For more information on built on science and based on form, Sherlock, which is able to Research and Innovation. “Work- bring them to the next level and Humber’s Research and 100 years of research and current uncover hidden concepts with- ing with Innovation 360, we are help them continue to have real Innovation work, visit thinking. in the world’s largest database prepared to help share insights impact.” www.humber.ca/research/. It is the world’s largest frame- of innovation data from more work and tool suite for online than 5,000 organizations. These analysis, design, implementa- important insights along with Ginger Grant, PhD tion, and execution of innova- access to the innovation manage- Dean, Research and Innovation tion management in any kind of ment assessment and benchmark- Humber College organization. The methodology ing tool, InnoSurvey®, will help has been developed and refined partner organizations gain market by practice in organizations and share and advance their strategic leveraged by experts globally in priorities. nnovation can be trans- 105 countries. “It is a great pleasure to formational for teams and Companies that leverage Inno- have established a strong edu- organizations alike. The key vation 360’s methodology and cational partnership between Iis tapping into the poten- tools to align their capabilities Canada and Europe,” said tial and strengthening innovation to their strategy can expect a Magnus Penker, CEO and capabilities across the institution. 20-25% increase in annual founder of Innovation 360. “It is These actions can help open eyes growth and up to 30% faster vital to address cultural, leader- and open doors to new opportuni- product and service development. ship and capabilities for innova- ties for growth. “Building innovation capacity tion management in a scientific Humber College is focused on has never been more important way, laying the foundation for Bringing industry helping partner organizations use and as the designated Canadian today and tomorrow, reshaping this information to gain market education provider of Innova- and revisioning how we tackle and education share and advance their strategic tion 360, Humber will be able to the great, grand challenges we priorities. give partners a competitive edge,” face as a society.” together. With this in mind, Humber said Rani Dhaliwal, Senior Vice- Throughout the COVID-19 recently became the designated President, Transformation and pandemic a culture of innovation Connect with Canada’s #1 college Canadian educational partner of Strategic Partnerships, Humber has proven to be a key ingredi- in research partnerships and the Innovation 360. College. “Through exclusive ent for organizations needing to designated Canadian educational Innovation 360 Group AB, a access to a suite of innovation change gears in times of uncer- partner for Innovation 360*. Swedish-based Innovation Solu- tools, expertly trained staff will tainty and crisis. humber.ca/research tions Firm, helps organizations work with businesses to assess, “Innovation isn’t always become innovation ready through and quickly focus resources and easy. It requires a collaborative a data-driven methodology and strategy on achieving goals.” approach and a growth mindset, *The world’s largest framework and tool suite for a suite of tools for innovation Through this collaboration, particularly when tackling chal- innovation management. management. The methodology, Humber’s partners will benefit lenges like a global pandemic,”

tion to meet a dire global shortage theory – the mathematical model- Re-Inventing Society Under Threat Continued from page 14 of cybersecurity professionals. ing of strategic interactions among Manufacturing “Even before the pandemic, different agents – to counter a type Creating jobs and strengthen- moved quickly, working with staff at these facilities would con- west coast to warn when an earth- there was a significant gap in of distributed attack that could ing Canada’s economy were the researchers at U of T, Sunny- tinue to be paid, and that funding quake hits, providing valuable filling positions, estimated at cause traffic disruptions. raison d’être behind Canada’s brook Research Institute and was available to help scientists seconds and minutes to protect between 50,000 and 100,000 “Ryerson has considerable Innovation Superclusters – a McMaster University, to isolate switch to COVID-19 research. human life and infrastructure. positions just in Canada. This is a research expertise in digital sci- $950-million federal initiative to the virus responsible for this “We secured their funding “All this funding is building particular priority for our industry ence, digital media and informa- encourage collaborations among deadly global pandemic. It was immediately in the first week capacity to do something greater, partners,” said Dr. Steven Liss, tion communications technolo- companies of all sizes, academ- the first lab in Canada to do so. of the pandemic,” said CFI whether it’s for the environment VP, Research and Innovation, at gies, as well as cybersecurity – an ics, incubators and innovators. Plans are underway to estab- President and CEO Dr. Roseann or health,” said O’Reilly Runte. Ryerson University. area with huge opportunities for But responding to a pandemic lish with its partner hospitals O’Reilly Runte. “We set up two “Science is important, not just Ryerson’s cybersecurity exper- us to be engaged in,” said Liss. wasn’t on anyone’s radar. an ‘Emerging and Pathogenic competitions, one for the colleges in meeting calamitous challenges tise is embedded throughout its “We have put a lot of emphasis on “When this program was set Infections Consortium’ (EPIC) and one for the universities and but in providing us the answers faculties, including energy sys- strengthening and deepening our up a couple of years ago I don’t at U of T to provide the capacity hospitals to help them re-purpose that will enable us to move for- tems and transportation. At expertise and scientific leadership think anyone thought it would be to confront existing and emerg- their infrastructure.” ward and achieve our human Ryerson’s Laboratory of Innova- in cybersecurity in many different used in situations of emergency ing pathogens, including those One unexpected outcome of potential.” tions in Transportation Lab, for areas across the university.” response,” said Jayson Myers, that may contribute to future the pandemic has been the light- example, researchers are develop- pandemics. ning speed at which research Protecting Against ing digital defences using game Continued on page 20 “Once this is in place, we will funders have been able to expe- Cyber Threats have an even greater ability to dite application reviews and Responding to 21st century develop innovative new approach- approvals to get grants out quick- threats increasingly depends on es to combat infectious disease, ly. Processes that usually take society’s ability to protect sys- and to help more Canadian com- several months were condensed tems and personal data from panies by engaging with them at to days or a few weeks. cyberattacks. The global pan- an earlier stage of their product For example, CFI funding demic has escalated these risks development,” said Gray-Owen. recipients usually require match- as more people move online for Research. Innovate. ing funds for projects from the work, healthcare, schooling and The Role of provinces or the private sector. business. Canadian universities, Change the future. Big Science In the wake of the pandemic, the in particular, are tempting targets University biosafety labs have CFI received government approv- for identify theft, financial fraud been among several large al to provide 100% of costs rather and stealing intellectual property. research facilities funded by the than the usual 40% for urgent One university working to Canada Foundation for Innova- research infrastructure related to safeguard Canada from these tion (CFI) that quickly pivoted to COVID-19. sophisticated and costly crimes take on the challenges posed by “We want to ensure the ongo- is Ryerson University. In 2018, the global pandemic. ing research doesn’t miss a beat – it partnered with five other uni- Another was the Sudbury and we did,” said O’Reilly Runte. versities to launch the Canadian Neutrino Observatory Lab, Canada’s big science facili- Shared Security Operations Cen- where Nobel Laureate Dr. Arthur ties provide an important front- tre (CanSOCC) to investigate how McDonald pivoted in just a few line defence against other types shared services can help large days from studying dark matter of emergencies as well. Western research universities protect them- to collaborating on an interna- University, for example, is home selves and respond to attacks. tional effort to invent a simple to the Insurance Research Lab for Another initiative, Ryerson’s ventilator that can be affordably Better Homes, a state-of-the-art Rogers Cybersecure Catalyst, was produced anywhere using off-the- facility that simulates hurricane- established as a national network shelf parts. A Canadian company force winds to make buildings to grow start-ups and scale-ups, is now manufacturing the ventila- more resilient to natural disasters. support applied research and tors and selling them around the Another major research development, public education world. endeavour, Ocean Networks and policy development, and per- For its part, the CFI moved Canada, has installed real-time haps most importantly, provide quickly to ensure all research underwater sensors off Canada’s accelerated training and certifica-

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Creative Accounts Nikita / Tyler Studio Rachel Project Manager Kelly researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 19 Canada’s TOP 100 CORPORATE R&D SPENDERS 2020 C I R&D Rank R&D Spending Revenue Intensity L R&D % Change Spending FY2019 FY2018 2018- FY2019 as % of 2019 2018 Company $000 $000 2019 $000 Revenu e** Industry

1 2 Magna International Inc.* $849,216 $761,872 11.5 $52,320,994 1.6 Automotive 2 3 Suncor Energy Inc. $830,000 $635,000 30.7 $38,989,000 2.1 Energy/Oil & Gas 3 4 Constellation Software Inc.* $701,930 $584,749 20.0 $4,630,881 15.2 Software & Computer Services 4 5 Pratt & Whitney Canada Corp. (fs) $629,533 $540,264 16.5 nd Aerospace 5 7 Bausch Health Companies Inc.* $624,970 $535,124 16.8 $11,412,667 5.5 Pharmaceuticals/Biotechnology 6 1 Bombardier Inc.* $577,202 $1,471,915 -60.8 $20,907,963 2.8 Aerospace 7 6 BCE Inc. $532,400 $537,100 -0.9 $23,964,000 2.2 Telecommunications Services 8 14 TELUS Corporation $530,000 $307,000 72.6 $14,658,000 3.6 Telecommunications Services 9 8 IBM Canada Ltd. (fs) $512,000 $512,000 0.0 nd Software & Computer Services 10 17 Canadian Natural Resources Limited $473,000 $265,000 78.5 $22,871,000 2.1 Energy/Oil & Gas 11 9 Shopify Inc.* $471,069 $298,884 57.6 $2,094,078 22.5 Software & Computer Services 12 11 Rogers Communications Inc. $442,412 $414,808 6.7 $15,073,000 2.9 Telecommunications Services 13 13 AMD Canada (fs) $429,819 $319,319 34.6 nd Electronic Systems & Parts 14 10 Open Text Corporation* $427,044 $419,108 1.9 $3,806,551 11.2 Software & Computer Services 15 12 Ericsson Canada Inc. (fs) $381,000 $368,000 3.5 nd Comm/Telecom Equipment 16 16 BlackBerry Limited* ++ $343,667 $283,758 21.1 $1,379,976 24.9 Software & Computer Services 17 15 CGI Group Inc. $302,781 $287,671 5.3 $12,111,236 2.5 Software & Computer Services 18 19 Huawei Canada (fs) $261,611 $186,742 40.1 nd Comm/Telecom Equipment 19 18 BRP Inc.++ $238,400 $221,700 7.5 $6,052,700 3.9 Other Manufacturing 20 20 CAE Inc. $232,100 $182,700 27.0 $3,304,100 7.0 Aerospace 21 22 Imperial Oil Limited $170,000 $150,000 13.3 $34,002,000 0.5 Energy/Oil & Gas 22 21 Cisco Canada (fs) $166,267 $158,110 5.2 nd Comm/Telecom Equipment 23 39 Zymeworks Inc.* $153,934 $73,445 109.6 $39,202 392.7 Pharmaceuticals/Biotechnology 24 27 Stars Group Inc.* + $137,836 $118,646 16.2 $3,354,998 4.1 Software & Computer Services 25 23 Hydro-Québec $132,000 $144,000 -8.3 $14,021,000 0.9 Electrical Power & Utilities 26 25 Sanofi (fs) (a) $131,026 $127,400 2.8 $796,400 16.5 Pharmaceuticals/Biotechnology 27 26 Sierra Wireless, Inc.* $115,077 $122,252 -5.9 $946,760 12.2 Comm/Telecom Equipment 28 29 Pfizer Canada ULC (fs) $101,618 $98,247 3.4 nd Pharmaceuticals/Biotechnology 29 33 Novelis Inc.* (fs) $95,537 $82,925 15.2 $16,355,369 0.6 Mining & Metals 30 31 Linamar Corporation $87,149 $90,664 -3.9 $7,416,624 1.2 Automotive 31 35 Evertz Technologies Limited $85,823 $80,804 6.2 $443,556 19.3 Comm/Telecom Equipment 32 34 Syncrude Canada Ltd. $78,207 $82,322 -5.0 nd Energy/Oil & Gas 33 32 EXFO Inc.* $76,923 $84,535 -9.0 $380,674 20.2 Comm/Telecom Equipment 34 38 Arbutus Biopharma Corporation* $76,431 $75,065 1.8 $5,779 1322.6 Pharmaceuticals/Biotechnology 35 30 Liminal BioSciences Inc. $75,686 $94,841 -20.2 $4,904 1543.4 Pharmaceuticals/Biotechnology 36 41 Descartes Systems Group Inc.* ++ $71,006 $62,028 14.5 $432,292 16.4 Software & Computer Services 37 44 Aurinia Pharmaceuticals Inc.* $70,148 $53,619 30.8 $422 Pharmaceuticals/Biotechnology 38 53 Titan Medical Inc.* $68,227 $42,574 60.3 $0 Medical Devices & Instrumentation 39 63 Teck Resources Limited $67,000 $35,000 91.4 $11,934,000 0.6 Mining & Metals 40 40 GlaxoSmithKline Inc. (fs) $65,165 $70,621 -7.7 $902,969 7.2 Pharmaceuticals/Biotechnology 41 42 Canadian Solar Inc.* $62,424 $57,261 9.0 $4,246,854 1.5 Energy/Oil & Gas 42 50 AstraZeneca Canada Inc. (fs) $62,296 $48,207 29.2 $618,239 10.1 Pharmaceuticals/Biotechnology 43 51 Enghouse Systems Limited $59,049 $47,540 24.2 $385,853 15.3 Software & Computer Services 44 49 Dorel Industries Inc.* $52,671 $49,002 7.5 $3,495,912 1.5 Other Manufacturing 45 45 Novartis Pharmaceuticals Canada Inc. (fs) $51,800 $52,000 -0.4 nd Pharmaceuticals/Biotechnology 46 28 Ontario Power Generation Inc. $51,000 $106,000 -51.9 $6,022,000 0.8 Electrical Power & Utilities 47 55 Martinrea International Inc. $48,782 $40,735 19.8 $3,863,659 1.3 Automotive 48 36 Optiva Inc.* $46,650 $79,705 -41.5 $160,400 29.1 Software & Computer Services 49 61 Kinaxis Inc.* $45,280 $35,795 26.5 $254,166 17.8 Software & Computer Services 50 64 Northland Power Inc. $44,200 $33,332 32.6 $1,658,977 2.7 Electrical Power & Utilities 51 66 Eli Lilly Canada Inc. (fs) $43,946 $29,238 50.3 nd Pharmaceuticals/Biotechnology 52 48 Resverlogix Corp.* $42,917 $49,086 -12.6 $0 Pharmaceuticals/Biotechnology 53 59 L3Harris WESCAM (fs) $41,359 $37,598 10.0 nd Aerospace 54 78 Acasti Pharma Inc. $38,961 $16,078 142.3 $0 Pharmaceuticals/Biotechnology 55 58 ADVANZ PHARMA Corp. Limited* + $38,641 $38,493 0.4 $674,491 5.7 Pharmaceuticals/Biotechnology 56 47 Pharmascience Inc. $38,458 $49,500 -22.3 $479,050 8.0 Pharmaceuticals/Biotechnology 57 60 Celestica Inc.* $37,684 $37,316 1.0 $7,813,185 0.5 Electronic Systems & Parts 58 57 Thales Canada Inc. (fs) $36,374 $38,852 -6.4 $713,916 5.1 Electronic Systems & Parts 59 52 Trillium Therapeutics Inc.* $36,358 $44,297 -17.9 $165 Pharmaceuticals/Biotechnology 60 62 Ballard Power Systems Inc.* $35,731 $35,034 2.0 $141,085 25.3 Machinery 61 56 Westport Fuel Systems Inc.* $33,401 $39,673 -15.8 $405,153 8.2 Other Manufacturing 62 67 Pason Systems Inc. $30,439 $26,997 12.7 $295,642 10.3 Software & Computer Services 63 65 Cascades Inc. $30,231 $30,791 -1.8 $4,996,000 0.6 Forest & Paper Products 64 90 Rio Tinto Iron & Titanium Inc. (fs) $29,637 $12,500 137.1 $1,247,000 2.4 Mining & Metals 65 77 Lightspeed POS Inc.* $27,171 $21,295 27.6 $102,770 26.4 Software & Computer Services 66 BELLUS Health Inc. $26,119 $7,185 263.5 $35 Pharmaceuticals/Biotechnology 67 69 Absolute Software Corporation* $25,507 $25,985 -1.8 $131,242 19.4 Software & Computer Services 68 68 Mediagrif Interactive Technologies Inc.+ $25,397 $26,510 -4.2 $83,082 30.6 Software & Computer Services 69 99 Héroux-Devtek Inc. $24,194 $11,282 114.4 $483,877 5.0 Aerospace 70 79 Resolute Forest Products Inc. (fs) $24,000 $15,600 53.8 $3,076,000 0.8 Forest & Paper Products 71 73 Winpak Ltd.* $22,425 $21,560 4.0 $1,159,502 1.9 Rubber & Plastics 72 71 Aptose Biosciences Inc.* $22,338 $24,272 -8.0 $0 Pharmaceuticals/Biotechnology 73 72 Computer Modelling Group Ltd. $21,206 $21,772 -2.6 $74,857 28.3 Software & Computer Services Innovation 74 Sangoma Technologies Corporation $20,748 $7,766 167.2 $109,648 18.9 Computer Equipment Atlas Canada 75 70 Cenovus Energy Inc. $20,000 $25,000 -20.0 $20,181,000 0.1 Energy/Oil & Gas 76 54 Lockheed Martin Canada (fs) $19,761 $40,764 -51.5 $578,105 3.4 Aerospace 77 83 Vecima Networks Inc. $19,040 $15,338 24.1 $85,032 22.4 Comm/Telecom Equipment innovationatlas.com 78 Neo Performance Materials Inc.* $19,009 $21,823 -12.9 $540,664 3.5 Mining & Metals 79 88 IMV Inc. $18,986 $12,852 47.7 $59 Pharmaceuticals/Biotechnology 80 82 Baylin Technologies Inc. $16,803 $15,363 9.4 $153,323 11.0 Comm/Telecom Equipment 81 80 Intertape Polymer Group Inc.* $16,622 $15,579 6.7 $1,537,239 1.1 Rubber & Plastics 82 Canopy Growth Corporation $15,238 $1,453 948.7 $253,431 6.0 Pharmaceuticals/Biotechnology 83 74 CES Energy Solutions Corp. $15,000 $20,000 -25.0 $1,277,257 1.2 Energy/Oil & Gas 84 75 Servier Canada Inc. (fs) $14,838 $17,920 -17.2 $105,494 14.1 Pharmaceuticals/Biotechnology 85 Aurora Cannabis Inc. $14,778 $1,679 780.2 $281,097 5.3 Pharmaceuticals/Biotechnology 86 TC Energy $14,423 $8,407 71.6 $13,255,000 0.1 Energy/Oil & Gas 87 98 TECSYS Inc. $14,392 $11,429 25.9 $76,449 18.8 Software & Computer Services follow us on twitter 88 100 Theratechnologies Inc.* $14,385 $10,324 39.3 $83,881 17.1 Pharmaceuticals/Biotechnology @R_Infosource 89 AcuityAds Holdings Inc. $13,834 $6,226 122.2 $119,134 11.6 Telecommunications Services 90 95 ShawCor Ltd. $12,647 $11,876 6.5 $1,489,489 0.8 Other Manufacturing 91 MEG Energy Corp. $12,000 $5,509 117.8 $3,931,000 0.3 Energy/Oil & Gas 92 96 Enlighten Innovations Inc. $11,969 $11,680 2.5 $0 Energy/Oil & Gas Research Infosource Inc. 93 DiaMedica Inc.* $11,618 $7,432 56.3 $0 Pharmaceuticals/Biotechnology is Canada’s source of R&D 94 Quest PharmaTech Inc.++ $11,264 $6,298 78.9 $0 Pharmaceuticals/Biotechnology intelligence. Data used for this 95 Oncolytics Biotech Inc. $11,135 $9,418 18.2 $0 Pharmaceuticals/Biotechnology table were extracted from our 96 93 Velan Inc.* ++ $10,964 $12,055 -9.1 $493,109 2.2 Other Manufacturing proprietary Canadian Corporate 97 87 POET Technologies Inc.* $10,298 $13,182 -21.9 $5,873 175.3 Electronic Systems & Parts R&D Database. Companies 98 NexJ Systems Inc. $9,411 $9,509 -1.0 $17,228 54.6 Software & Computer Services wishing to be included in future 99 NexOptic Technology Corp. $9,203 $8,613 6.9 $0 Electronic Systems & Parts 100 Essa Pharma Inc.* $8,885 $6,612 34.4 $0 Pharmaceuticals/Biotechnology editions of the Top 100 List, or who wish to adjust their figures Notes: should contact us directly. 1. Data were obtained through annual reports, financial statements, securities commission filings, other *Converted to CDN$ at annual average 2019 = 1.3269; 2018 = 1.2957 (Bank of Canada) company issued documents, or through a survey. **Based on companies with $2 million or more of revenue + For further information, 2. We have attempted, whenever possible, to provide gross R&D spending before deduction of Not current name/acquired/merged investment tax credits or government grants. ++Fiscal 2020 figures were used for year-ended January or February please visit 3. We have attempted, wherever possible, to provide revenue net of interest and investment income. fs = Foreign subsidiary (includes revenue and R&D spending for Canadian operations only) researchinfosource.com 4. FY2018 R&D spending figures may have been adjusted as more accurate information became available. nd = Not disclosed 5. Canadian-owned company results include worldwide revenue and R&D spending; foreign subsidiaries (fs) (a) Sanofi Pasteur Limited and sanofi-aventis Canada Inc. (including Sanofi Genzyme Canada). © Research Infosource Inc. 2021 for their Canadian operations only. Unauthorized reproduction prohibited. 20 | February 25, 2021 Canada’s Innovation Leaders 2020 researchinfosource.com

CANADA’S TOP 100 Top 100 – Leading Industries Industry % of Total Software & Computer Services (18) 24 Corporate R&D Spenders Pharmaceuticals/Biotechnology (27) 14 Energy/Oil & Gas (10) 13 Another Strong Year for R&D Spending Growth Industry Performance Corporate R&D While total Top 100 R&D spending expanded by In Fiscal 2019, 18 companies in the Software Aerospace (6) 11 Canada’s Top 100 Corporate R&D Spenders record- 7.5% in Fiscal 2019, many firms demonstrated & Computer Services sector accounted for 24% Telecommunications Services (4) 11 ed a solid 7.5% gain in their combined research and R&D spending growth well in excess of that. The of total Top 100 R&D spending, up from 23% Communications/Telecom Equipment (8) 8 development (R&D) spending in Fiscal 2019. Total leading Tier 1 companies for year-over-year R&D in Fiscal 2018. Twenty-seven Pharmaceuticals/ Automotive (3) 7 R&D spending reached $13.46 billion. R&D spend- spending growth were Zymeworks Inc. (109.6%), Biotechnology firms combined for 14% of Top ing rose at 69 companies, declined at 30 and did not Canadian Natural Resources Limited (78.5%) and 100 R&D spending, while 10 Energy/Oil and Gas change at one other. Combined revenue of the 89 TELUS Corporation (72.6%). Tier 2 R&D growth performers accounted for 13% of the total. International, at a still-impressive $849.2 million.) companies that reported revenue was $411.8 billion leaders were Acasti Pharma Inc. (142.3%), Teck In Fiscal 2019, R&D growth was especially Suncor Energy Inc.’s $830.0 million of R&D in Fiscal 2019, which was a year-over-year increase Resources Limited (91.4%) and Titan Medical Inc. strong in the following sectors: Mining & Met- (2nd position overall) put the natural resource sec- of 1.7% over Fiscal 2018. (60.3%). Tier 3 leaders were Canopy Growth Cor- als (up 38.7%), Energy/Oil and Gas (up 33.9%), tor in focus, with sector firms together accounting The leading R&D spender was Magna Interna- poration (948.7%), Aurora Cannabis Inc. (780.2%) Electronic Systems & Parts (up 25.4%) and Tele- for 13% of the Top 100 total. Holding 3rd place tional Inc., which devoted $849.2 million to R&D and BELLUS Health Inc. (263.5%). communications Services (up 20.0%). on the Top 100 list was Constellation Software (up 11.5%), followed by Suncor Energy Inc. ($830.0 Inc. ($701.9 million), reminding us of the impor- million, up 30.7%) and Constellation Software Inc. R&D Intensity Bucking the Trend tance of digital industries. R&D stalwart Pratt & ($701.9 million, up 20.0%). Pratt & Whitney Cana- Overall R&D intensity – R&D spending as a per- Normally, Research Infosource expects R&D Whitney Canada Corp. moved up to 4th place da was in 4th position with $629.5 million of R&D cent of revenue – was 2.6% for the 89 firms that spending trends to broadly align with revenue ($629.5 million) and signals that Canada’s aero- (up 16.5%) and Bausch Health Companies Inc. provided revenue for Fiscal 2019. However, many trends. In Fiscal 2019 ICT Manufacturing sector space sector is still strong. rounded out the top five R&D spenders with $625.0 firms performed above the mean. In Tier 1, Zyme- experienced a -7.5% drop in revenues, but posted The fact that Top 100 R&D spending expanded million (up 16.8%). works Inc. led devoting 392.7% of revenue to R&D, an overall 0.9% gain in R&D spending. Firms in at a faster pace than revenues shows that corporate BlackBerry Limited spent 24.9% and Shopify Inc. the Pharmaceuticals/Biotechnology sector posted R&D leaders still value the importance of investing $100 Million Dollar Club 22.5%. Tier 2 leaders were Liminal BioSciences revenue gains of 6.1% and their R&D spending in the future. Fiscal 2020 will go down as the year Twenty-eight Top 100 firms each reported R&D Inc. (1,543.4%), Arbutus Biopharma Corporation growth was even higher at 17.6%. ICT Services of COVID-19 and all bets are off on what this may spending in excess of $100 million, thus qualify- (1,322.6%) and Optiva Inc. (29.1%). In Tier 3, sector firms’ revenues grew by 5.2%, but their portend for corporate R&D. ing for membership in Research Infosource’s $100 POET Technologies Inc. (175.3%), NexJ Systems R&D spending expanded by 18.0%. Energy/Oil & Million Club. In Fiscal 2019, total Club members’ Inc. (54.6%) and Mediagrif Interactive Technolo- Gas firms had a 0.3% gain in revenues and a 36.6 R&D spending was $10.9 billion, accounting for gies Inc. (30.6%) were the R&D intensity leaders. increase in R&D outlays. Top 100 Corporate R&D Spenders 81% of total Top 100 R&D spending. Zymeworks Extremely high R&D intensity results typically Key Demographics FY2019 Inc. and Pfizer Canada ULC were new to the Club. indicate companies in start-up or early-stage mode. This Year and Next R&D Spending Growth Last year we said that “Canada’s corporate R&D (% Change 2018 -2019) R&D Spenders Tiers Regional Performance spending statistics have always been skewed by 20 50% or more When the Top 100 firms are grouped into three In Fiscal 2019, 42 companies headquartered in the performance of one or two large Canadian 28 10.1% - 49.9% R&D spending tiers (Tier 1 – $100 million or Ontario reported combined R&D spending of multinationals such as Nortel, BlackBerry and more of R&D spending, Tier 2 – $30 million-$99.9 $6.41 billion, followed by 28 Quebec-based com- more recently, Bombardier. The era of large- 21 0.1% - 10% million, Tier 3 – less than $30 million), three panies ($4.10 billion) and 29 firms located in West- performer dominance may be coming to an end 31 0% or less firms emerged as the respective tier leaders: Tier ern Canada ($2.93 billion). Overall R&D growth as our “national champions” fade.” Fiscal 2019 1 – Magna International Inc. ($849.2 million), Tier jumped by a substantial 36.8% in Western Canada affirmed that view. It was the first year in many R&D Intensity 2 – Novelis Inc. ($95.5 million) and Tier 3 – Rio and 12.8% in Ontario, but fell by -12.6% in Quebec where no firm spent more than $1 billion on (R&D Spending as % of Revenue) Tinto Iron and Titanium Inc. ($29.6 million). largely due to a decline at Bombardier Inc. R&D. (The largest R&D spender was Magna 18 20.0% or more 27 5.0% - 19.9%

Top Corporate R&D Spenders by Tier FY2019 34 0.01 - 4.9% R&D Spending R&D Spending Growth (% Change 2018-2019) R&D Intensity* (R&D Spending as % of Revenue) 21 Unable to calculate Rank Tier 1 $000 Rank Tier 1 % Rank Tier 1 % Company Revenue 1 Magna International Inc. $849,216 1 Zymeworks Inc. 109.6 1 Zymeworks Inc. 392.7 $1 billion 2 Suncor Energy Inc. $830,000 2 Canadian Natural Resources Limited 78.5 2 BlackBerry Limited 24.9 37 or more 3 Constellation Software Inc. $701,930 3 TELUS Corporation 72.6 3 Shopify Inc. 22.5 $100.0 million - 28 $999.9 million Less than Rank Tier 2 $000 Rank Tier 2 % Rank Tier 2 % 24 $100 million

1 Novelis Inc. (fs) $95,537 1 Acasti Pharma Inc. 142.3 1 Liminal BioSciences Inc. 1,543.4 NUMBER OF COMPANIES 11 Not disclosed 2 Linamar Corporation $87,149 2 Teck Resources Limited 91.4 2 Arbutus Biopharma Corporation 1,322.6 3 Evertz Technologies Limited $85,823 3 Titan Medical Inc. 60.3 3 Optiva Inc. 29.1 Bucking the Revenue Trend (% Change 2018-2019) Rank Tier 3 $000 Rank Tier 3 % Rank Tier 3 % Revenue 1 Rio Tinto Iron & Titanium Inc. (fs) $29,637 1 Canopy Growth Corporation 948.7 1 POET Technologies Inc. 175.3 Growth 2 Lightspeed POS Inc. $27,171 2 Aurora Cannabis Inc. 780.2 2 NexJ Systems Inc. 54.6 R&D 3 BELLUS Health Inc. $26,119 3 BELLUS Health Inc. 263.5 3 Mediagrif Interactive Technologies Inc. 30.6 35 16 26 12 Growth Notes: 1. R&D Spending Tiers: Tier 1 = $100 million or more of R&D spending, Tier 2 = $30 million-$99.9 million, Tier 3 = less than $30 million. *Based on companies with $2 million or more of revenue fs = Foreign subsidiary (included revenue and R&D spending for Canadian operations only) 11 unable to calculate

“Urban Alliance is a partnership our local government and the university “This slow burning pandemic is Society Under Threat platform that encourages community- increases public trust that decisions are already killing about 700,000 people Continued from page 18 engaged scholarship by the university to made with the best available evidence per year and it’s expected to increase to support the city in its decision making,” at hand.” 10 million deaths per year by 2050 which CEO of the Next Generation Manu- Myers said many NGen-supported said Dr. William Ghali, VP (Research) at is more than the number of people who facturing Canada (NGen) supercluster, projects will prove crucial as Canada the University of Calgary. Drug Resistance: “A Slow currently die of cancer,” said Hoffman, an industry-led not-for-profit of more prepares for a post-pandemic recovery, a The partnership would prove even Burning Pandemic” who also holds the Dahdaleh Distin- than 3,000 members, primarily small and big part of which will focus on a lack of more valuable in 2013 when univer- If there’s a silver lining from the COVID- guished Chair in Global Governance mid-sized companies. domestic manufacturing capability that sity researchers worked with the City of 19 pandemic, it might be the atten- and Legal Epidemiology at York. “The “But those economic metrics are only has exposed supply chain vulnerabilities. Calgary on community resilience strate- tion this crisis has brought to infectious reason we don’t think about it is because part of the story,” added Myers. “Our proj- “The pandemic has shown us that we gies in response to the most destructive disease threats that transcend national the cause of death isn’t attributed to ects have contributed to health care – sav- do not have the manufacturing capability to flood to hit the province in its history. borders. Addressing such grand chal- a drug-resistant infection. People just ing lives in many cases – and contributed to produce many of the products, components Seven years later the Urban Alliance lenges requires collective global action. know that their friend or family member the environment, water and food security, or materials needed to fight COVID-19.” was called upon to help with another Fortunately many of the top experts in died of pneumonia.” energy management and decarbonisation.” Advanced manufacturing can help solve crisis. this field work in Canada. Antimicrobial resistance, like “One Saturday night in early March – Just over a year ago, the World Health COVID-19 and climate change, requires during Hockey Night in Canada – I got a Organization designated the Global international cooperation but politics, The pandemic has shown us that we call from the president of the university, Strategy Lab at York University as the economic considerations and public atti- do not have the manufacturing capability to Ed McCauley, telling me that the mayor WHO Collaborating Centre on Global tudes can hinder these efforts. The Glob- produce many of the products, components or and the premier needed data to help them Governance of Antimicrobial Resistance. al Strategy Lab is working on solutions. “ decide how to respond to the COVID-19 The lab advises the world’s governments “We’re building a science about how materials needed to fight COVID … situation. We mobilized fast. Experts and public health organizations on how countries can work together to address advanced manufacturing can help solve this challenge from the Centre for Health Informatics, to design laws, policies and institutions this global health threat,” said Hoffman. JAYSON MYERS the O’Brien Institute for Public Health that address transnational health threats. This includes designing international Chief Executive Officer Next Generation Manufacturing Canada (NGen) and our School of Public Policy began Its expertise spans multiple disciplines, institutional arrangements that “not only work the very next day to provide the city including law, epidemiology, political solve the problem but are also politi- One NGen-supported consortium in this challenge, said Myers, by incorporat- and the province with relevant and timely science and ethics. cally feasible, legally acceptable and Western Canada is developing new oil ing new technologies and business process- data,” said Ghali. sands and mineral processing technolo- es to “radically improve” the productivity The first action was the formation of gies to reduce greenhouse gas emissions, and flexibility of manufacturing. a rapid response team – the COVID-19 We’re building a science about how countries and clean tech solutions that could elimi- “It’s not going to be business as Data Analytics Advisory Group – which can work together to address this global health threat nate the need for toxic tailings ponds. usual… The future will be about doing examined available case, death and testing DR. STEVEN HOFFMAN An early NGen project supported the things much better.” data to assess how public health measures “ Director, Global Strategy Lab development of a new manufacturing pro- mitigate spread of the virus. The group’s Dahdaleh Distinguished Chair in Global Governance & Legal Epidemiology cess that radically reduces the cost and A Model for Academic- online data tracker, which is updated daily, York University time to produce viral vectors – critical Municipal Collaboration has become an essential tool in helping components used in the manufacture of Emergencies like pandemics and floods city officials make science-based policy “In a globalized world, we’re more continually incentivize compliance with stem cell-based therapies to fight cancer also weren’t top of mind when the City of decisions on everything from school re- interconnected and interdependent than the measures that are involved.” and rare diseases. Calgary collaborated with the University openings and retail closures to bylaws and ever which means that the threats and the Such agreements could pave the way Like many others in Canada’s of Calgary in 2007 to create Urban Alli- public education programs. opportunities that we face are increas- for establishing surveillance systems that research ecosystem, NGen was also able ance. This partnership enabled the city and “The collaboration and the output ingly collective. They defy national bor- track how microbes are evolving or com- to swiftly change gears when the pan- the university to formally work together to have been significant. While the advisory ders,” said Dr. Steven Hoffman, Director mit all countries to funding the develop- demic began, including waiving its usual expedite the transfer of research to address group was initially activated through our of the Global Strategy Lab, which has ment of new antibiotics. administrative fee (equal to 2.5% of total important policy issues. partnership with the city, we’ve also tackled thorny issues such as tobacco And, if countries fail to act collec- project cost) for many large projects. Urban Alliance was built on a his- been working with the province, and we control and health misinformation. tively? “That’s where COVID-19 pro- “We were able to move at the speed tory of collaboration dealing with issues incorporated inputs from national and The Toronto lab is now providing the vides lessons,” Hoffman warned. “The of business,” he explained. “Within like transportation system optimization, international sources, like Johns Hopkins WHO with technical guidance, policy current pandemic gives us a window two weeks we had approved about sanitation and water fluoridation. Since University,” said Ghali, adding that the analysis and international legal advice into a future that we really don’t want 12 projects that were COVID-related, its formation, Urban Alliance has sup- interactive data tracker is also open and on global governance frameworks and if we allow antimicrobial resistance to everything from a ventilator that was ported more than 100 research initiatives available to the public. regulations to tackle antimicrobial resis- continue unabated.” being developed by Starfish Medical on and projects, including ones focusing on “Our governments had to make some tance – something the WHO has identi- Debbie Lawes, Debbie@dovercourtedito- Vancouver Island, to face masks and face social challenges like affordable housing, very tough decisions,” added Ghali, “but fied as one of the top 10 global threats to rial.ca, is an Ottawa-based writer specializ- shields to test kits.” race relations and poverty reduction. the established relationship between public health. ing in science, technology and innovation.

Use the Atlas to ... Innovation Atlas Canada u Find experts in any field of science, technology, u Develop research and business partnerships u Search for companies by industry sector or engineering, social science, humanities u Identify co-op education/training opportunities NAICS code (200,000+ records) u Understand local innovation strengths, clusters u More...! innovationatlas.com u Identify R&D companies (54,000+ records) u Conduct keyword searches (e.g. “nanotechnology”) For a free demonstration or pricing information: Email: [email protected] Telephone: 647-345-3434 ext. 22 researchinfosource.com Canada’s Innovation Leaders 2020 February 25, 2021 | 21

LEADING THE WAY Canadian solutions for a global crisis Based at McMaster University, Canada’s Global Nexus for Pandemics and Biological Threats is focused on one goal: beating COVID-19 and

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