BOOK REVIEWS the pages of medical history." Following this theme, ings in their particular approach to investigating Trimble, a long-standing authority in such matters, brain-behavior relationships. has given us a most useful and concise monograph on The basic organizational principle of the book is to this very issue. Fully packed with information on both carefully discuss and link detailed lesion foci seen on epilepsy and psychiatric illness, this work will be ap- computed tomography (CT) and magnetic resonance preciated by any serious clinician or researcher as a imaging with concomitant neurobehavioral analyses, source of information and as a gateway to the liter- using a case study approach. The book begins with a ature--current and historical. critical discussion of lesion analysis in central nervous Trimble confronts head-on the "chicken and egg" system disorders as a model to investigate human problem--supplying the psychiatric and neuroscien- cognition. Subsequent sections illustrate how de- tific (more neuroanatomical than neurochemical) tailed investigations of various well-characterized background to support the hypothesis for epilepsy brain lesions disrupt functional systems that subserve and psychoses arising from common etiological perception, memory, and language. The largest por- events and/or as one being the sequela of the other. tion of the book is devoted to Damasio's system- Does this come dangerously close to arguing for the atized use of CT and MRI as tools for neuroanatom- re-introduction of the "epileptic psychosis"--after so ical localization. While the neurobehavioral aspects many years of hard work to rid the language of "epi- of various brain lesions are well-discussed, the nat- leptic personality"? Perhaps--and perhaps it is an ural emphasis in this volume is the imaging method- appropriate correction for the excessive denial of any ology, which contains beautifully presented illus- psychiatric accompaniments to the epilepsy problem. trations and reproductions. In fact, in the final chapter However, Trimble treads with both caution and au- ("Roadmaps to Neuroanatomy") and appendix, a thority as he develops the neuropsychiatric element neuroanatomical template system is presented in in epilepsy. One would have hoped to find some dis- exceptional detail, likely to facilitate systematized cussion of the evidence concerning any linkage be- investigations and replications in other laboratories. tween effective psychotherapy and its salutary impact This book will undoubtedly attract a wide reader- epileptic phenomena, and vice versa. To be sure, ship of clinicians and researchers who have interests pretty much any issue of importance relating to this in cognitive neuroscience. This includes, but is not topic is noted (if at times too briefly). There are com- limited to, basic and applied research in neurology, mentaries of psychometrics, laterality, surgery, inter- psychiatry, neuropsychology, neurolinguistics, and ictal phenomena, pharmacological treatment (al- neuroradiology. The book is well-written, and the though hardly anything on psychotherapy and no price makes it affordable to students, who will likely mention of behavior therapies), and more. In short, find it required reading. this is a valuable little book that belongs in the library Robert S. Goldman, Ph.D. of anyone concerned with either epilepsy or mental illness. Departments of Psychology and Psychiatry David I. Mostofsky, Ph.D. University of Michigan Boston University Ann Arbor, MI, U.S.A. Boston, MA, U.S.A.

Principles and Practice of Pediatrics, by F. A. Oski, Lesion Analysis in Neuropsychology, by Hanna C. D. DeAngelis, R. D. Feigin, and J. B. Warshaw. Damasio and Antonio R. Damasio. New York: Oxford Philadelphia: Lippincott, 1990, 2,155 pp. Price: University Press, 1989, 227 pp. Price: $39.95. $95.0O. In a well-organized and superbly detailed volume, This, the newest of general pediatric textbooks, is Drs. H. Damasio and A. Damasio present their sys- only modestly awkward to handle as a single large tematically conceived analysis approach to investi- volume. It is priced favorably compared to other gating the neuroanatomical substrate of complex general pediatric texts. It accomplishes authoritative human cognitive processes. The material is pre- status by employing 261 contributors who are recog- sented sequentially and hierarchically, such that nized for their knowledge of the topics discussed. those not familiar with the whole of the Damasio's After sitting many hours over many sessions to re- work will readily comprehend the conceptual issues, view this volume, I cannot recommend such a global methodological factors, and extensive empirical find- reading to accomplished practitioners. For them, this

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