Publications for Jane Hanrahan

2021 href="http://dx.doi.org/10.1177/0271678X18755628">[More Lee, K., Tan, E., Hanrahan, J., Chircop, C., Michael, F., Ong, J. Information] (2021). Effect of Antipsychotics and Non-Pharmacotherapy for the Management of Delirium in People Receiving Palliative 2018 Care. Journal of Pain & Palliative Care Pharmacotherapy, Du, J., Hanrahan, J., Solomon, V., Williams, P., Groundwater, 34(4), 225-236. [Mor Binding of Barbital to a Synthetic Macrocyclic Receptor. A e Information] Charge Density Study. The Journal of Physical Chemistry A, van Nieuwenhuijzen, P., Parker, K., Liao, V., Houlton, J., Kim, 122(11), 3031-3044. [More (2021). Targeting GABAC Receptors Improves Post-Stroke Information] Motor Recovery. Brain Sciences, 11(3), 315( 1-19). [More 2017 Information] Carroll, P., Hanrahan, J. (2017). A shot in the arm: Pharmacist- 2020 Administered influenza vaccine in New South Wales. Australian Journal of Pharmacy, 98(1165), 56-59. [Mo (2020). Evaluation of a vaccination training program for re Information] pharmacy graduands in Australia. Currents in Pharmacy Nematollahi, A., Sun, G., Jayawickrama, G., Hanrahan, J., Teaching and Learning, 12(7), 850-857. [More of a novel human kynurenine aminotransferase-2 reversible Information] inhibitor. Medicinal Chemistry Research, 26(10), 2514-2519. Hanrahan, J., Carroll, P. (2020). Student-led interprofessional [More influenza vaccination clinic in a time of coronavirus. Medical Information] Education, 54(11), 1078-1079. Flavonoid href="http://dx.doi.org/10.1111/medu.14323">[More Actions on Receptors for the Inhibitory Neurotransmitter Information] GABA. In Goncalo C Justino (Eds.), Flavonoids: From Al Kazman, B., Harnett, J., Hanrahan, J. (2020). The Biosynthesis to Human Health, (pp. 335-350). Rijeka: InTech. phytochemical constituents and pharmacological activities of [More annona atemoya: A systematic review. Pharmaceuticals, Information] 13(10), 1-16. [More (2017). GABA-(rho) receptors: distinctive functions and Information] molecular pharmacology. British Journal of Pharmacology, Chan, W., McLachlan, A., Hanrahan, J., Harnett, J. (2020). The 174(13), 1881-1894. [More systematic review. Journal of Pharmacy and Pharmacology, Information] 72(1), 1-16. [More (2017). Medicinal plants used by traditional healers in Jordan, Information] the Tafila region. Pharmacognosy Magazine, 13(49), S95-S101. 2019 [More Information] Solomon, V., Tallapragada, V., Chebib, M., Johnston, G., Karim, N., Khan, I., Abdelhalim, A., Abdel-Halim, H., Hanrahan, J. (2019). GABA allosteric modulators: An overview Hanrahan, J. (2017). Molecular docking and antiamnesic effects of recent developments in non-benzodiazepine modulators. of nepitrin isolated from Rosmarinus officinalis on scopolamine- European Journal of Medicinal Chemistry, 171, 434-461. [More Pharmacotherapy, 96, 700-709. href="http://dx.doi.org/10.1016/j.biopha.2017.09.121">[More Devenish, S., Johnston, G., Chebib, M., Hanrahan, J. (2019). Information] Optimising the transient expression of GABA(A) receptors in Wong, C., Marshall, N., Grunstein, R., Ho, S., Fois, R., Hibbs, adherent HEK293 cells. Protein Expression and Purification, D., Hanrahan, J., Saini, B. (2017). Spontaneous adverse event 154, 7-15. [More 2012. The Journal of Clinical Sleep Medicine, 13(2), 223-234. Information] [More Clarkson, A., Boothman-Burrell, L., Dosa, Z., Nagaraja, R., Jin, Information] L., Parker, K., van Nieuwenhuijzen, P., Neumann, S., Gowing, E., Gavande, N., Ahring, J., Hanrahan, J., Chebib, M., et al 2016 (2019). The flavonoid, 2'-methoxy-6-methylflavone, affords Lee, H., Absalom, N., Hanrahan, J., van Nieuwenhuijzen, P., neuroprotection following focal cerebral ischaemia. Journal of Ahring, J., Chebib, M. (2016). A pharmacological Cerebral Blood Flow and Metabolism, 39(7), 1266-1282. [More Information] Beta3delta receptors via the Beta3(+)delta(-) interface. Brain Rae, C., Nasrallah, F., Balcar, V., Rowlands, B., Johnston, G., Research, 1644, 222-230. [More Role(s) of GABAI Receptors in the Brain. Journal of Information] Neuroimmune Pharmacology, 10(3), 45-456. [More Hanrahan, J., Groundwater, P. (2016). An investigation of the Information] differential effects of ursane triterpenoids from Centella Bui, J., Day, C., Hanrahan, J., Winstock, A., Chaar, B. (2015). asiatica, and their semi-synthetic analogues, on GABAA Senior nurses' perspectives on the transfer of opioid receptors. Chemical Biology & Drug Design, 88(3), 386-397. substitution treatment clients from clinics to community [More pharmacy. Drug and Alcohol Review, 34(5), 495-498. href="http://dx.doi.org/10.1111/dar.12209">[More Naffa'a, M., Absalom, N., Solomon, V., Collins, M., Hibbs, D., Information] Hanrahan, J. (2016). Investigating the Role of Loop C Hamid, K., Ng, I., Tallapragada, V., Hibbs, D., Hanrahan, J., Hydrophilic Residue 'T244' in the Binding Site of (rho)1 Groundwater, P. (2015). The Differential Effects of Resveratrol GABAC Receptors via Site Mutation and Partial Agonism. and trans-e-Viniferin on the GABA-Induced Current in PloS One, 11(5), 1-21. [More Oocytes. Journal of Pharmacy and Pharmaceutical Sciences, Information] 18(4), 328-338. [More (2016). Structure of the PLP-Form of the Human Kynurenine Information] Aminotransferase II in a Novel Spacegroup at 1.83 A Chua, H., Absalom, N., Hanrahan, J., Viswas, R., Chebib, M. Resolution. International Journal of Molecular Sciences, 17(4), (2015). The Direct Actions of GABA, 2-Methoxy-6- 1-11. [More Methylflavone and General Anaesthetics at β3γ2L GABAA Information] Receptors: Evidence for Receptors with Different Subunit Nematollahi, A., Sun, G., Jayawickrama, G., Hanrahan, J., Stoichiometries. PloS One, 10(10), 1-19. [More Mechanism of Action of a Reversible Inhibitor of Recombinant Information] Human KAT-2: A Promising Lead in Neurodegenerative and Samad, A., Adeel, M., Khan, D., Badshah, S., Muhammad, Z., Cognitive Disorders. Molecules, 21(7), 1-9. [More Furoquinoline Alkaloids from Zanthoxylum armatum. Asian Information] Journal of Chemistry, 27(7), 2468-2472. [More Information] Carland, J., Yamamoto, I., Hanrahan, J., Abdel-Halim, H., Lewis, T., Absalom, N., Chebib, M. (2015). A Hydrophobic 2014 Area of the GABA p1 Receptor Containing Phenylalanine 124 Abdelhalim, A., Chebib, M., Aburjai, T., Johnston, G., Influences Both Receptor Activation and Deactivation. Journal Hanrahan, J. (2014). GABAA Receptor Modulation by of Molecular Neuroscience, 55(2), 305-313. [More Biological Chemistry, 4(2), 148-159. href="http://dx.doi.org/10.4236/abc.2014.42019">[More Abdelhalim, A., Karim, N., Chebib, M., Aburjai, T., Khan, I., Information] Johnston, G., Hanrahan, J. (2015). Antidepressant, Anxiolytic Blednov, Y., Benavidez, J., Black, M., Leiter, C., Osterndoff- and Antinociceptive Activities of Kahanek, E., Johnson, D., Borghese, C., Hanrahan, J., Johnston, Constituents from Rosmarinus Officinalis. Journal of Pharmacy G., Chebib, M., et al (2014). GABAA Receptors Containing p1 and Pharmaceutical Sciences, 18(4), 448-459. Ethanol in Mice. PloS href="http://dx.doi.org/10.18433/j3pw38">[More One, 9(1), 1-16. href="http://dx.doi.org/10.1371/journal.pone.0085525">[More Naffa'a, M., Chebib, M., Hibbs, D., Hanrahan, J. (2015). Information] Comparison of templates for homology model of rho1 GABAC Hall, B., Karim, N., Chebib, M., Johnston, G., Hanrahan, J. receptors: More insights to the orthosteric binding site's (2014). Modulation of Ionotropic GABA Receptors by 6- structure and functionality. Journal of Molecular Graphics and Methoxyflavanone and 6-Methoxyflavone. Neurochemical Modelling, 62, 43-55. [More href="http://dx.doi.org/10.1007/s11064-013-1157-2">[More Information] Information] Hanrahan, J., Chebib, M., Johnston, G. (2015). Interactions of Samad, A., Badshah, S., Khan, D., Ali, F., Amanullah, M., flavonoids with ionotropic GABA receptors. Advances in Hanrahan, J. (2014). New prenylated carbazole alkaloids from Pharmacology, 72, 189-200. [More Research, 16(12), 1126-1131. href="http://dx.doi.org/10.1080/10286020.2014.967228">[More Jayawickrama, G., Sadig, R., Sun, G., Nematollahi, A., Nadvi, Information] N., Hanrahan, J., Gorrell, M., Church, W. (2015). Kynurenine aminotransferases and the prospects of inhibitors for the 2013 treatment of schizophrenia. Current Medicinal Chemistry, Gavande, N., Kim, H., Doddareddy, M., Johnston, G., Chebib, 22(24), 2902-2918. [More Journal of Pharmacology, 165(4), 965-977. href="http://dx.doi.org/10.1111/j.1476- 5381.2011.01615.x">[More Information] Meng, Q., Roubin, R., Hanrahan, J. (2013). Ethnopharmacological and bioactivity guided investigation of Karim, N., Wellendorph, P., Absalom, N., Bang, L., Jensen, M., five TCM anticancer herbs. Journal of Ethnopharmacology, Hansen, M., Lee, H., Johnston, G., Hanrahan, J., Chebib, M. 148(1), 229-238. [More a4b1/b3d GABAA receptor subtypes indicate a different Information] binding mode for GABA at these receptors. Biochemical Pharmacology, 84(4), 549-557. [More R. (2013). Factors influencing pharmacy services in opioid Information] substitution treatment. Drug and Alcohol Review, 32(4), 426- 434. [More Yamamoto, I., Carland, J., Locock, K., Gavande, N., Absalom, Information] N., Hanrahan, J., Allan, R., Johnston, G., Chebib, M. (2012). Structurally Diverse GABA Antagonists Interact Differently Karim, N., Wellendorph, P., Absalom, N., Johnston, G., with Open and Closed Conformational States of the p1 Hanrahan, J., Chebib, M. (2013). Potency of gaba at human Receptor. ACS Chemical Neuroscience, 3(4), 293-301. [More oocytes: a mini review. Amino Acids, 44(4), 1139-1149. href="http://dx.doi.org/10.1007/s00726-012-1456-y">[More Information] Hanrahan, J. (2012). Sunscreens. Australian Prescriber, 35(5), 148-151. [More Johnston, G., Allan, R. (2013). γ-Aminobutyric Acid(C) Information] (GABAC) Selective Antagonists Derived from the Bioisosteric Modification of 4-Aminocyclopent-1-enecarboxylic Acid: 2011 Amides and Hydroxamates. Journal of Medicinal Chemistry, 56(13), 5626-5630. [More Hanrahan, J., Chebib, M. (2011). 3-Hydroxy-2'-methoxy-6- Information] methylflavone: A potent anxiolytic with a unique selectivity profile at GABBA receptor subtypes. Biochemical 2012 Pharmacology, 82(12), 1971-1983. [More Karim, N., Curmi, J., Gavande, N., Johnston, G., Hanrahan, J., Information] Tierney, L., Chebib, M. (2012). 2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective Chaar, B., Brien, J., Hanrahan, J., McLachlan, A., Penm, J., activating and modulating actions at GABA(A) receptors. Pont, L. (2011). Experimental Education in Australian British Journal of Pharmacology, 165(4), 880-896. [More Information] Hanrahan, J., Chebib, M., Johnston, G. (2011). Flavonoid Akladios, F., Nadvi, N., Park, J., Hanrahan, J., Kapoor, V., modulation of GABA(A) receptors. British Journal of Gorrell, M., Church, W. (2012). Design and synthesis of novel Pharmacology, 163(2), 234-245. [More Information] href="http://dx.doi.org/10.1016/j.bmcl.2011.12.138">[More Gavande, N., Karim, N., Johnston, G., Hanrahan, J., Chebib, M. Information] (2011). Identification of Benzopyran-4-one Derivatives Yamamoto, I., Absalom, N., Carland, J., Doddareddy, M., (Isoflavones) as Positive Modulators of GABAA Receptors. Gavande, N., Johnston, G., Hanrahan, J., Chebib, M. (2012). ChemMedChem: chemistry enabling drug discovery, 6(8), 1340- Differentiating Enantioselective Actions of GABOB: A 1346. [More rho1 Receptors. ACS Chemical Neuroscience, 3(9), 665-673. href="http://dx.doi.org/10.1021/cn3000229">[More Ng, C., Kim, H., Gavande, N., Yamamoto, I., Kumar, R., Information] Mewett, K., Johnston, G., Hanrahan, J., Chebib, M. (2011). Nguyen, T., Howard, S., Hanrahan, J., Groundwater, P., Platts, Medicinal Chemistry of p GABAc Receptors. Future Medicinal J., Hibbs, D. (2012). Experimental and Theoretical Charge Chemistry, 3(2), 197-209. [More Terephthaloyl Receptor Complexed to Adipic Acid. The Information] Journal of Physical Chemistry A, 116, 5618-5628. [More Hanrahan, J., Chebib, M. (2011). Naringin directly activates Information] inwardly rectifying Mohammad, A., Hanrahan, J., Sainsbury, E., Chaar, B. (2012). potassium channels at an overlapping binding site to tertiapin- Fitness to practise in pharmacy: a study of impairment in Q. British Journal of Pharmacology, 163(5), 1017-1033. [More Information] href="http://dx.doi.org/10.1007/s11096-012-9610-x">[More Gavande, N., Yamamoto, I., Salam, N., Tu-Hoa, A., Burden, P., Information] Johnston, G., Hanrahan, J., Chebib, M. (2011). Novel Cyclic Phosphinic Acids as GABAC F Receptor Antagonists: Design, Therapeutics, 328(2), 448-457. [More Letters, 2(1), 11-16. href="http://dx.doi.org/10.1021/ml1001344">[More Mewett, K., Fernandez, S., Pasricha, A., Pong, A., Devenish, S., Information] Hibbs, D., Chebib, M., Johnston, G., Hanrahan, J. (2009). Chaar, B., Hanrahan, J., Day, C. (2011). Provision of Opioid Synthesis and biological evaluation of flavan-3-ol derivatives as Substitution Therapy Services in Australian Pharmacies. positive modulators of GABAA receptors. Bioorganic and Australasian Medical Journal, 4(4), 210-216. [More href="http://dx.doi.org/10.1016/j.bmc.2009.08.062">[More Information] Information] 2010 Hanrahan, J., Johnston, G. (2009). Synthesis of -Aminobutyric Acid Analogs. In Hughes, A.B. (Eds.), Amino Acids, Peptides Nasrallah, F., Maher, A., Hanrahan, J., Balcar, V., Rae, C. and Proteins in Organic Chemistry Volume 1 Origins and (2010). Gamma-Hydroxybutyrate and the GABAergic Synthesis of Amino Acids, (pp. 573-689). Weinheim, Germany: footprint: a metabolomic approach to unpicking the actions of Wiley - V C H Verlag GmbH & Co. KGaA. [More href="http://dx.doi.org/10.1111/j.1471- Information] 4159.2010.06901.x">[More Information] Fernandez, S., Nguyen, M., Yow, T., Chu, C., Johnston, G., Gavande, N., Johnston, G., Hanrahan, J., Chebib, M. (2010). Hanrahan, J., Chebib, M. (2009). The flavonoid glycosides, Microwave-enhanced synthesis of 2,3,6-trisubstituted myricitrin, gossypin and naringin exert anxiolytic action in pyridazines: Application to four-step synthesis of gabazine (SR- mice. Neurochemical Research, 34(10), 1867-1875. [More 4136. [More Information] Information] 2008 Johnston, G., Chebib, M., Hanrahan, J., Mewett, K. (2010). Neurochemicals for the Investigation of GABAc Receptors. Abdel-Halim, H., Hanrahan, J., Hibbs, D., Johnston, G., Neurochemical Research, 35(12), 1970-1977. [More antagonist actions at GABA(C) receptors. Chemical Biology Information] and Drug Design (Print), 71(4), 306-327. [More Information] Matin, A., Gavande, N., Kim, M., Yang, N., Salam, N., Fernandez, S., Mewett, K., Hanrahan, J., Chebib, M., Johnston, Hanrahan, J., Roubin, R., Hibbs, D. (2009). 7-Hydroxy- G. (2008). Flavan-3-ol derivatives are positive modulators of benzopyran-4-one Derivatives: A Novel Pharmacophore of GABA(A) receptors with higher efficacy for the alpha(2) Peroxisome Proliferator-Activated Receptor and - (PPAR and ) subtype and anxiolytic action in mice. Neuropharmacology, Dual Agonists. Journal of Medicinal Chemistry, 52(21), 6835- 55(5), 900-907. [More href="http://dx.doi.org/10.1016/j.neuropharm.2008.06.069">[M Information] ore Information] Ryan, G., Hanrahan, J., Krass, I., Sainsbury, E., Smith, L. Kumar, R., Chebib, M., Hibbs, D., Kim, H., Johnston, G., (2009). Best Practices Assessment to Guide Curricular Change Salam, N., Hanrahan, J. (2008). Novel gamma-aminobutyric in a Bachelor of Pharmacy Program. American Journal of acid rho(1) receptor antagonists; Synthesis, pharmacological Pharmaceutical Education, 73(1), 1-8. [More Medicinal Chemistry, 51(13), 3825-3840. href="http://dx.doi.org/10.1021/jm7015842">[More Information] Meng, Q., Niu, Y., Niu, X., Roubin, R., Hanrahan, J. (2009). Ethnobotany, phytochemistry and pharmacology of the genus 2007 Caragana used in traditional Chinese medicine. Journal of Ethnopharmacology, 124(3), 350-368. [More Wooller, S., Johnston, G. (2007). (3- Information] Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonists. Neuropharmacology, 52(3), 779-787. [M Mewett, K., Allan, R., Duke, R., Johnston, G., Hanrahan, J. ore Information] (2009). Guanidino Acids Act as p1 GABAc Receptor Antagonists. Neurochemical Research, 34(10), 1704-1711. [More Information] Hanrahan, J., Mewett, K., Chebib, M., Matos, S., Eliopoulos, C., Crean, C., Kumar, R., Burden, P., Johnston, G. (2006). Chebib, M., Hanrahan, J., Johnston, G. (2009). Neurologically- Diastereoselective synthesis of (+/-)-(3- active Compounds (II). Patent No. 2002364767. aminocyclopentane)alkylphosphinic acids, conformationally Hanrahan, J., Johnston, G., Kumar, R., Chebib, M. (2009). restricted analogues of GABA. Organic and Biomolecular Neurologically-active Compounds (III). Patent No. 1773740. Chemistry, 4(13), 2642-2649. [More Chebib, M., Hinton, T., Schmid, K., Brinkworth, D., Qian, H., Information] Matos, S., Kim, H., Abdel-Halim, H., Kumar, R., Johnston, G., Hanrahan, J. (2009). Novel, potent and selective GABAC Johnston, G., Hanrahan, J., Chebib, M., Duke, R., Mewett, K. antagonists inhibit myopia development and facilitate learning (2006). Modulation of Ionotropic GABA Receptors by Natural and memory. Journal of Pharmacology and Experimental Products of Plant Origin. In S.J. Enna (Eds.), GABA, (pp. 285- 316). United States: Academic Press. [More href="http://dx.doi.org/10.1107/S160053680300730X">[More Information] Information] Johnston, G., Hanrahan, J., Chebib, M., Duke, R., Mewett, K. Johnston, G., Chebib, M., Hanrahan, J., Mewett, K. (2003). (2006). Modulation of ionotropic GABA receptors by natural GABAc receptors as drug targets. CNS and Neurological products of plant origin. Advances in Pharmacology, 54, 285- Disorders, 2(4), 260-268. 316. [More Information] G. (2003). Semisynthetic preparation of amentoflavone: a 2005 negative modulator at gabaa receptors. Bioorganic and Medicinal Chemistry Letters, 13(14), 2281-2284. [More Information] modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at 2002 alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors Campbell, E., Chebib, M., Duke, R., Hall, B., Hanrahan, J., expressed in Xenopus oocytes. European Journal of Johnston, G., Mewett, K. (2002). Epigallocatechin gallate, from Pharmacology, 512(2-3), 97-104. [More GABA receptors. 5th Australia/Japan Symposium on Drug Information] Design and Development. Chebib, M., Hanrahan, J., Johnston, G., Kumar, R. (2005). Patent No. 6962907. 2001 Crittenden, D., Kumar, R., Hanrahan, J., Chebib, M., Jordan, M. Hall, B., Hanrahan, J., Johnston, G., Hambley, T., Hibbs, D. (2005). Stabilization of zwitterions in solution: Phosphinic and (2001). 6-Methylflavone. Acta Crystallographica. Section E: phosphonic acid GABA analogues. The Journal of Physical Structure Reports Online, E57. Chemistry A, 109(37), 8398-8409. [More (2001). An improved, versatile synthesis of the GABAc Information] antagonists (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic 2004 acid (TPMPA) and (piperidin-4-yl)methylphosphinic acid (P4MPA). Royal Chemical Society. Journal. Perkin Hall, B., Chebib, M., Hanrahan, J., Johnston, G. (2004). Transactions 1, 1, 2389-2392. [More acid action by 6-methylflavone at human recombinant a1h2g2L Information] and a1h2 GABAA receptors. European Journal of Pharmacology, 491(1), 1-8. [More Information] Chebib, M., Hanrahan, J., Mewett, K., Duke, R., Johnston, G. (2004). Ionotropic Gaba Receptors As Therapeutic Targets For Memory And Sleep Disorders. Annual Reports in Medicinal Chemistry, 39(1), 13-23. [More Information] Carland, J., Moore, A., Hanrahan, J., Mewett, K., Duke, R., Johnston, G., Chebib, M. (2004). Mutations Of The 2' Proline In The M2 Domain Of The Human Gabac Rho1 Subunit Alter Agonist Responses. Neuropharmacology, 46, 770-781. [M ore Information] Allan, R., Greenwood, J., Hambley, T., Hanrahan, J., Hibbs, D., Itani, S., Tran, H., Turner, P. (2004). Studies On Pyridazine Azide Cyclisation Reactions. Organic and Biomolecular Chemistry, 2(12), 1782-8-1788. [More Information] 2003 Hibbs, D., Hanrahan, J., Hursthouse, M., Knight, D., Overgaard, J., Turner, P., Piltz, R., Waller, M. (2003). Experimental and theoretical charge distribution in (Z)-N- methyl-C-phenylnitrone. Organic and Biomolecular Chemistry, 11(6), 1034-1040. [More Information] Waller, M., Hibbs, D., Overgaard, J., Hanrahan, J., Hambley, T.