<<

Yangtze River Pharmaceutical Group Justin Yangtze River Pharmaceutical Group 1 South Yangtze River Road, Taizhou, Jiangsu, China Tel., WhatsApp and Wechat: +86-15261051195 Skype: [email protected] QQ: 348196586

Recommended Products Delayed-Release Capsules - A routine drug for peptic ulcer - The first choice of Proton Pump Inhibitors (PPIS) for Gastroesophageal Reflux Disease (GERD) - EU GMP certified and exported to Germany - Plan to submit CTD dossiers to Australian TGA in 2018 - Quality in line with BP for Injection - Plan to gain US ANDA and its API DMF in 2019 - With own API Sodium for Injection - Plan to gain EU MA in 2018 - Top 1 market share in China Parecoxib Sodium for Injection - Plan to gain MA by TGA in 2018 - CTD dossiers available - Quality in line with EP Enalapril Maleate Tablets - A first-line hypotensive drug as Angiotensin-Converting Enzyme Inhibitor (ACEI) - EU GMP certified (Germany) - Exported to HK area and Philippines - Finished Quality Consistency Evaluation - Quality in line with USP - Top 1 market share in China Losartan Potassium Tablets - Biphenyl Tetrazolium Angiotensin II Receptor Blocker (ARB) - Stable depressurization - To stay peaceful day and night - Quality in line with EP Iohexol Injection - Non-ionic contrast agent - Clear and reliable image 1 / 21

Yangtze River Pharmaceutical Group - Several strengths for choice - Exported to Philippines and Honduras - CTD dossiers available - Quality in line with USP - Top 1 market share in China Desloratadine Citrate Disodium Tablets - The 3rd Generation of antihistamine drug - Outstanding therapeutic effect and unequaled safety - Reassuring choice for antianaphylaxis - Exclusive product with patent Tamoxifen Citrate Tablets - A classic medication of endocrine therapy for breast cancer - For both premenopausal and postmenopausal treatment - Exported to Egypt and Ethiopia - Quality in line with USP - With own API Anastrozole Tablets - The 3rd generation of Aromatase Inhibitor (AI) - A first-line drug for Postmenopausal Breast Cancer Approved by FDA - Exported to Ethiopia - CTD dossiers available - With own API Paclitaxel Injection - The most effective drug for ovarian cancer - The first drug used for metastatic ovarian cancer approved by FDA - A safe & effective drug used alone or in combination, and for initial or refractory treatment - Exported to HK area, Vietnam and Mongolia - CTD dossiers available - Quality in line with USP Zoledronic (for) Injection - A first-line Drug for Hypercalcinemia Caused by Malignant Tumor - Strong Anti-bone-resorption, to improve Administration Time-Efficiency - Long Lasting Effect: One Dosage per Month - Exported to Moldova, Ethiopia and Mongolia - With own API Amlodipine Besylate and Benazepril Hydrochloride Tablets (I) - The best combination to treat hypertension - Strong antihypertensive effects with remarkably improved target rate - Protect vessels and target organs in an all-around way to decrease cardiovascular events effectively - Optimum combination of CCB and ACEI - Simplify treatment with better compliance

2 / 21

Yangtze River Pharmaceutical Group Glimepiride Tablets - A classic choice for multifunctional anti-hypertensive action - Lower blood glucose level safely to reduce the occurrence of hypoglycemia - EU GMP certified (Germany) - With BE study Amlodipine Besylate Tablets - Stable onset to make blood pressure compliance process more secure - Stable anti-hypertensive control lasting for 24 hours - Provide muti-protection for organs to prevent the damage of target organ - Applicable to a wide range of people - With BE study Finasteride Tablets - Inhibit 90% of dihydrotestosterone synthetised in prostate tissue - Preoperative use for reducing bleeding and risk during the BPH surgery - Significantly reduce the volume of prostate and alleviate obstruction - Improve the flow rate of urine and relieve the symptoms - A good protector for the BPH surgery - With BE study Propofol MCT/LCT Emulsion for Injection or Infusion - With 50% MCT & 50% LCT - Significantly relieve injection pain - Obviously reduce hepatic load - Less onset of hypertriglyceridemia - Safe and convenient for intravenous anesthesia for infants over one month - With CTD dossiers - Quality in line with RLD

CHEMICAL MEDICINES

ANALGESIC AGENTS PRODUCT NAME STRENGTH Status Exclusive Dezocine Injection 1mL:5mg×4amps product in China Plan to register in TGA in 2018; Parecoxib Sodium for Injection 20mg; 40mg CTD dossiers; EP Propofol MCT/LCT Emulsion for 20mL: 0.2g Injection or Infusion 50mL: 0.5g CTD dossiers 50mL: 1.0g

3 / 21

Yangtze River Pharmaceutical Group

ANESTHESIA AGENTS PRODUCT NAME STRENGTH 10mL:23.8mg×2amps; Ropivacaine Mesylate Injection 10mL:89.4mg×2amps Vecuronium Bromide for Injection 4mg×6vials

ANTI-ALLERGIC AGENTS PRODUCT NAME STRENGTH Status Cetirizine Hydrochloride Tablets 10mg×12tabs CTD dossiers Exclusive product in Desloratadine Citrate Disodium Tablets 8.8mg×3tabs; 8.8mg×6tabs China, with patent Loratadine Tablets 10mg×6tabs; 10mg×12tabs 10mg×3tabs; 10mg×5tabs; Top 1 market Rupatadine Fumarate Tablets 10mg×10tabs share in China

ANTI-MICROBIAL AGENTS PRODUCT NAME STRENGTH Status Azithromycin Lactobionate for 250mg×6vials Injection Balofloxacin Tablets 100mg×12tabs Cefaclor Sustained-release 125mg×6caps×2plates;

Capsules 125mg×6caps×4plates Cefalexin Capsules 125mg×10caps×4plates USP Cefetamet Pivoxil Hydrochloride 90.65mg×8tabs Tablets Cefminox Sodium for Injection 1.0g×2vials USP; Cefonicid Sodium for Injection 0.5g×6vials; 1.0g×6vials Top 1 market share in China 1.0g×6vials (Cefoperazone 0.5g and Cefoperazone Sodium and Sulbactam 0.5g); Sulbactam Sodium for Injection 2.0g×6vials (Cefoperazone 1.0g and Sulbactam 1.0g) Cefoxitin Sodium for Injection 1.0g×6vials USP Cefpirome Sulfate for Injection 1g Top 1 market 4 / 21

Yangtze River Pharmaceutical Group share in China Cefprozil Tablets 250mg×10tabs USP Cefradine Capsules 250mg×6caps×4plates USP

Ceftazidime for Injection 500mg×6vials; 1.0g×6vials USP

Ciprofloxacin Hydrochloride 250mg×12caps;

Capsules 250mg×12caps×2plates Clarithromycin Dispersible 125mg×6tabs; 250mg×6tabs Tablets Clindamycin Phosphate for 300mg×6vials Injection Fluconazole (and Sodium 5mL:200mg×5amps;

Chloride) Injection 100mL:200mg 50mg×6tabs; Fluconazole Tablets 50mg×6tabs×2plates; 150mg×1tab Ganciclovir for Injection 250mg

200mg×6caps; Gatifloxacin Capsules 200mg×12caps

Gatifloxacin and Sodium 100mL:200mg Chloride Injection

Levofloxacin Hydrochloride 100mg×6caps; Top 1 market Capsules 100mg×12caps share in China

50mL:250mg; 100mL:100mg; Levofloxacin Hydrochloride and 100mL:200mg; Top 1 market Injection 100mL:300mg; share in China 100mL:500mg; 150mL:750mg 2mL:100mg×4amps; 2mL:100mg×6amps; Levofloxacin Hydrochloride 2mL:200mg×4amps; Injection 2mL:200mg×6amps; 3mL:300mg×4amps Moxifloxacin Hydrochloride for 250mL:400mg Injection Ofloxacin Capsules 200mg×10caps Ornidazole Capsules 250mg×6caps×2plates Pazufloxacin Mesylate and 100mL:300mg

5 / 21

Yangtze River Pharmaceutical Group Sodium Chloride Injection CTD dossiers; 50mg×12caps; Roxithromycin Capsules Top 1 market 150mg×12caps share in China Top 1 market Roxithromycin Granules 50mg/sachet×10sachets share in China Tigecycline for Injection 50mg 100mL:400mg; Tinidazole Injection 200mL:800mg Vorionazole Dispersible Tablets 200mg×6tabs

ANTI-PYRETIC-ANALGESIC & NON-STEROIDAL ANTI-INFLAMMATORY AGENTS PRODUCT NAME STRENGTH Status Ambroxol Hydrochloride for Injection 15mg×6vials Diclofenac Potassium Tablets 25mg×12tabs×2plates USP Erdosteinate Tablets 150mg×12tabs/bottle BP; 7.5mg×10tabs; Meloxicam Tablets Top 1 market 7.5mg×10tabs×2plates share in China 250mg×10tabs; Naproxen Delayed-Release Tablets 250mg×10tabs×2plates; 250mg×10tabs×3plates Paracetamol, , Artificial 250mg×10caps×2plates; Cow-bezoar and Chlorphenamine 250mg×10caps×20plates; Maleate Capsules 250mg×12caps Paracetamol Pseudoephedrin Hydrochloride and Chlorphenamine 120mL Maleate Oral Solutions 325mg Paracetamol, Paracetamol 30mg Pseudoephedrine Hydrochloride and Chlorphenamine Hydrochloride, 2mg Maleate Tablets Chlorphenamine Maleate, 4tabs Pediatric Paracetamol, Atificial Cow-bezoar and Chlorphenamine 6g×10sachets Maleate Granules

CIRCULATORY SYSTEM AGENTS PRODUCT NAME STRENGTH Status Amlodipine Besylate and Benazepril 12.5mg (Benazepril Top 1 market

6 / 21

Yangtze River Pharmaceutical Group Hydrochloride Tablets (I) Hydrochloride 10mg, share in China Amlodipine 2.5mg)×7tabs 5mg×7tabs; 5mg×7tabs×2plates; Amlodipine Besylate Tablets CTD dossiers 5mg×7tabs×3plates; 5mg×7tabs×4plates 5mg×8tabs×2plates; CTD dossiers; 5mg×16tabs; USP; Enalapril Maleate Tablets 10mg×8tabs×2plates; Top 1 market 10mg×16tabs; share in China 10mg×16tabs×2plates Fasudil Hydrochloride Injection 2mL:30mg Irbesartan Capsules 75mg×12caps 75mg×6tabs×2plates; 75mg×12tabs; Irbesartan Tablets USP 75mg×12tabs×2plates; 75mg×12tabs×4plates 20mg×12caps; Isosorbide Mononitrate Capsules 20mg×12caps×4plates Isosorbide Mononitrate Injection 5mL:20mg×4amps 2.5mg×7tabs; Levamlodipine Besylate Tablets 2.5mg×7tabs×2plates 50mg×7tabs; Losartan Potassium Tablets 50mg×7tabs×2plates; USP 100mg×7tabs Top 1 market Lovastatin Capsules 20mg×12caps share in China Milrinone Lactate Injection 5mL:5mg×2amps 10mg×8tabs×2plates; 10mg×16tabs; Nifedipine Extended-release Tablets 10mg×16tabs×2plates; 10mg×16tabs×4plates 10mg×10caps; 10mg×10caps×2plates; Simvastatin Capsules 10mg×12caps×2plates; 10mg×12caps×4plates 1mg×6caps×2plates; 1mg×6caps×8plates; Terazosin Hydrochloride Capsules 2mg×6caps×2plates; 2mg×6caps×8plates

DIAGNOSIS AGENTS

7 / 21

Yangtze River Pharmaceutical Group PRODUCT NAME STRENGTH Status 50mL:13.5g(I); 50mL:16g(I); CTD dossiers; Iodixanol Injection 100mL:27g(I); 100mL:32g(I) USP

50mL:15g(I) CTD dossiers; 50mL:17.5g(I) USP; Iohexol Injection 75mL:22.5g(I) Top 1 market share 100mL:30g(I) in China 100mL:35g(I)

DIGESTIVE SYSTEM AGENTS PRODUCT NAME STRENGTH Status Azasetron Hydrochloride and Sodium Top 1 market 50mL:10mg Chloride Injection share in China USP; Dyclonine Hydrochloride Gel 10mL:100mg×12vials Top 1 market share in China Plan to register Esomeprazole Sodium for Injection 40mg in US FDA in 2019 Granisetron Hydrochloride and Glucose 50mL:3mg Injection 15mg×14tabs; Delayed-Release Tablets 15mg×14tabs×2plates Top 1 market Matrine for Injection 150mg×6vials share in China Metadoxine Oral Solutions 20mL×6vials Montmorillonite Powder 3g/sachet×10sachets EU GMP certified (Germany); Omeprazole Delayed-Release Capsules 20mg×14caps/bottle Plan to submit dossiers in TGA in 2018; BP Palonosetron Hydrochloride Injection 5mL:0.25mg Plan to gain EU MA in 2019; Pantoprazole Sodium for Injection 40mg×6vials Top 1 market share in China 30mg×10tabs; Racecadotril Tablets 30mg×10tabs×2plates

8 / 21

Yangtze River Pharmaceutical Group Somatostatin for Injection 3mg×6vials Top 1 market Acexamate Capsules 150mg×12caps×2plates share in China

HORMONE & REGULATING ENDOCRINE SECRETION FUNCTION AGENTS PRODUCT NAME STRENGTH Status 10mg×7tabs; Alendronate Sodium Tablets 10mg×7tabs×4plates Top 1 market Epalrestat Capsules 50mg×10caps share in China 50mg×10tabs; Top 1 market Epalrestat Tablets 50mg×9tabs×2plates share in China Glipizide Extended-Release 5mg×12tabs;

Tablets 5mg×12tabs×2plates 2mg×10tabs; EU GMP certified Glimepiride Tablets 2mg×10tabs×3plates (Germany) (Metformin Hydrochloride: Metformin Hydrochloride and Top 1 market 250mg, Glipizide: Glipizide Tablets share in China 2.5mg)×6tabs×3plates 30mg×9tabs×3plates; Nateglinide Tablets 30mg×9tabs×16plates Risedronate Sodium Tablets 5mg×30tabs/bottle 0.2mg×10caps; Voglibose Capsules 0.2mg×10caps×5plates Zoledronic Acid for Injection 4mg Zoledronic Acid Injection 5ml:4mg

NERVOUS SYSTEM AGENTS PRODUCT NAME STRENGTH Status Injection 2mL:100mg×4amps Cytidine Disodium Triphosphate 2mL:20mg×4amps Injection Donepezil Hydrochloride Capsules 5mg×7caps Doxapram Hydrochloride Injection 5mL:100mg×4amps Edaravone Injection 5mL:10mg×6amps Glycerol and Fructose Injection 250mL Mecobalamine Capsules 0.5mg×50caps/bottle CTD dossiers Mecobalamine Injection 1mL:0.5mg×5amps CTD dossiers Mecobalamine Tablets 0.5mg×16caps×3plates Nimodipine Injection 20mL:4mg×2amps

9 / 21

Yangtze River Pharmaceutical Group

ONCOLOGY AGENTS PRODUCT NAME STRENGTH Status Anastrozole Tablets 1mg×14tabs/bottle CTD dossiers Folinate for Injection 100mg×6vials BP Docetaxel Injection 0.5mL:20mg; 2mL:80mg CTD dossiers; USP Doxifluridine Tablets 200mg×36tabs/bottle Oxaliplatin for Injection 50mg USP 5mL:30mg; Paclitaxel Injection CTD dossiers; USP 16.7mL:100mg Pemetrexed Disodium for 100mg; 500mg CTD dossiers Injection USP; 10mg×30tabs/bottle; Tamoxifen Citrate Tablets Top 1 market share 10mg×60tabs/bottle in China Vindesine Sulfate for Injection 1mg BP

SPECIAL DRUGS PRODUCT NAME STRENGTH Status Imiquimod Cream 2g:100mg×2tubes Tretinoin Cream 10g:5mg USP Triamcinolone Acetonide and Econazole 15g Cream

OTHERS PRODUCT NAME STRENGTH Status Calcium and Zinc Gluconates Oral 10mL×12vials Solutions Doxofylline and Glucose Injection 100mL:300mg 150mg×12tabs/bott Erdosteine Tablets le 1mg×10tabs; Finasteride Tablets 5mg×10tabs Fructose and Sodium Chloride Injection 250mL: 12.5g USP Top 1 market Invert Sugar and Electrolytes Injection 250mL; 500mL share in China 20mg×4vials; Ozagrel Sodium for Injection 40mg×4vials; 80mg Thymopentin for Injection 1mg×6vials Tranexamic Acid Injection 5mL:500mg×4amp BP

10 / 21

Yangtze River Pharmaceutical Group s 20mg×10tabs×2pla Top 1 market Trospium Chloride Tablets tes share in China Note: All the above products are not available in patent covered areas.

11 / 21

Yangtze River Pharmaceutical Group

TRADITIONAL CHINESE MEDICINES CIRCULATORY SYSTEM Product Name Main Ingredients Actions and Indications Strength Breviscapine Breviscapine. With Calcium Promoting blood circulation to remove blood stasis, activating 40mg×6tabs/pl Dispersible phosphate, Croscarmellose Sodium, meridians to stop pain. For stroke sequela, coronary heart ate×4plates Tablets microcrystalline cellulose and twelve alkane disease and stenocardia. Sodium lauryl sulfate, sodium , silicon dioxide, stearate as excipients. Ginkgo Leaf Gingko Leaf Extract For promoting blood circulation to remove blood stasis and (9.6mg/Total Tablets obstacles in the channels. It is used for cardioplegic pain, stoke, flavonol hemiplegia, stiff tongue and impeded speech caused by glucosides obstruction of collaterals by blood stasis and for treatment of 9.6mg and stable coronary disease, with angina pectoris and cerebral terpene infarction with above symptoms. . lactones 2.4mg)×12tabs/ plate Ginkgo Leaf Gingko Leaf Extract For promoting blood circulation to remove blood stasis and (19.2mg/Total Tablets obstacles in the channels. It is used for cardioplegic pain, stoke, flavonol hemiplegia, stiff tongue and impeded speech caused by glucosides obstruction of collaterals by blood stasis in the artery and for 19.2mg and treatment of stable coronary disease, angina pectoris and terpene cerebral infarction with above symptoms. lactones 4.8mg)×12tabs/

12 / 21

Yangtze River Pharmaceutical Group

plate Mailuotong Codonopsis Radix, Angelicae Sinensis Radix, It has the effects of benefiting Qi for activating blood 0.42g/cap×6cap Capsules Pheretima, Salviae Miltiorrhizae Radix Et circulation, resolving stasis and relieving pain. It is indicated s×2plates Rhizoma , Carthami Flos, Equiseti Hiemalis for the treatment of heart and chest pain, chest distress, Herba, Puerariae Lobatae Radix, Sophorae shortness of breath, headache and dizziness, and coronary heart Immaturus Flos, Crataegi Fructus, and disease or angina pectoris with the above symptoms, such Chuanxiong Rhizoma symptoms of angina pectoris due to coronary artery disease; and numbness of limbs and hemiplegia caused by stroke.

Mailuotong Codonopsis Radix, Angelicae Sinensis Radix, It has the effects of benefiting Qi for activating blood 6g/sachet×3sac Granules Pheretima, Salviae Miltiorrhizae Radix Et circulation, resolving stasis and relieving pain. It is indicated hets Rhizoma , Carthami Flos, Equiseti Hiemalis for the treatment of heart and chest pain, chest distress, Herba, Puerariae Lobatae Radix, Sophorae shortness of breath, Headache and dizziness, and coronary heart Immaturus Flos, Crataegi Frucus, Chuanxiong disease or angina pectoris with the above symptoms, such Rhizoma, Vitamine C, , and symptoms of angina pectoris due to coronary disease; and numbness of limbs and hemiplegia caused by stroke.

DIGESTIVE SYSTEM Product Name Main Ingredients Actions and Indications Strength Biling Weitong Litseae Fructus, Toosendan Fructus, Corydalis For promoting flow of Qi and blood circulation, regulating the 5g/sachet Granules Rhizoma (processing with ), Rhei Radix Et stomach and relieving pain. The drug can be used for Rhizoma (processing with wine), Coptidis stomachache caused by Qi stagnation and blood stasis, and Rhizoma, Euodiae Fructus, Cyperi Rhizoma chronic superficial gastritis if the above symptoms are observed. (processing with vinegar), Citri Fructus, Citri Sarcodactylis Fructus, Sepiae Endoconcha, and

13 / 21

Yangtze River Pharmaceutical Group

Arcae Concha (Calcined). With Dextrin, Steviosin, Hydroxypropyl Cellulose as excipients.

Jindan Tablets Gentianae Radix Et Rhizoma, Lysimachiae Herba, For relieving inflammation and cholagogic effect. The drug can 0.32g×100t Polygoni Cuspidati Rhizoma Et Radix, Fel suis be used for treatment of acute or chronic cholecystitis, abs/bottle cholelithiasis and infection of the biliary tract.

Shenqu Xiaoshi Stir-Baked Massa Medicata Fermentata, Charred Promoting digestion and invigorating the stomach, invigorating 10mL/vial Oral Solution Crataegi Fructus, Stir-Baked Hordei Fructus the spleen and regulating Qi. It is used for children's weakness ×6vials Germinatus, Paeoniae Radix Alba, Codonopsis of the spleen and stomach caused by improper feeding, eating or Radix, Poria, Stir-Baked Atractylodis drinking. The symptoms are anorexia, poor appetite, intake Macrocephalae Rhizoma in Bran, Aucklandiae reduced and so on caused by food stagnation. Radix, Amomi Fructus, Corydalis Rhizoma (Stir-Baked with Vinegar) and Glycyrrhizae Radix Et Rhizoma Praeparata Cum Melle

Weisu Granules Perillae Caulis, Cyperi Rhizoma, Citri Reticulatae For regulating Qi, relieving flatulence, regulating the stomach 5g/sachet (sugar free) Pericarpium, Citri Fructus, Citri Sarcodactylis and relieving pain. The main function is on stomachache caused Fructus, Aurantii Fructus, Arecae Semen, and by Qi stagnation. The symptoms are stamachache and bloating, Galli Gigerii Endothelium Corneum (prepared). affecting the ribs on two sides; with belching or winding from With Dextrin and as excipients. the bowels, the pain would be relieved; with lingering anger, the pain would be severer; discomfort in the stomach, loss of appetite, have difficulty in defecation, etc. The drug can also be used for the treatment of chronic gastritis if the above symptoms are exhibited.

14 / 21

Yangtze River Pharmaceutical Group

Weisu Granules Perillae Caulis, Cyperi Rhizoma, Citri Reticulatae For regulating Qi, relieving flatulence, regulating the stomach 15g/sachet (with sugar ) Pericarpium, Citri Fructus, Citri Sarcodactylis and relieving pain. The main function is on stomachache caused Fructus, Aurantii Fructus, Arecae Semen, and by Qi stagnation. The symptoms are stomachache and bloating, Galli Gigerii Endothelium Corneum (prepared). affecting the ribs on two sides; with belching or winding from With Dextrin, Stevioside and sodium the bowels, the pain would be relieved; with lingering anger, the carboxymethyl starch as excipients. pain would be severer; discomfort in the stomach, loss of appetite, have difficulty in defecation, etc. The drug can also be used for the treatment of chronic gastritis if the above symptoms are exhibited.

IMMUNITY FUNCTION ADJUSTMENT DRUGS Product Name Main Ingredients Actions and Indications Strength HuangQijing Astragali Radix. With refined honey, polysorbate Supplementing blood and Qi, strengthening body resistance for 10ml×12vi Oral Solution 80, sorbic acid, stevioside, Ethylparaben, and arresting sweating. It is used for the treatment of deficiency in als orange fl avor as excipients. Qi and blood, asthenia and spontaneous sweating, tiredness and weakness, lack of energy, frailty caused by prolonged illness, and poor spleen and stomach.

Zhengyuan Epimedii Folium, Dry Ginseng Radix Et Rhizoma, Benefiting Qi and invigorating the spleen, tonifing the kidney 0.45g×24c Capsules Astragali Radix Praeparata Cum Melle, Testudinis and filling the essence. It is an adjuvant drug for radiotherapy aps/bottle Carapax Et Plastrum, Trionycis Carapax, to Steam and chemotherapy of tumor. Symptoms: fatigue, loss of Qi, or Simmer Ligustri Lucidi Fructus with Yellow shortness of breath, poor appetite, lumbar and spinal soreness, Rice Wine, Atractylodis Macrocephalae spontaneous sweating, loss of weight, etc. For lung cancer Rhizoma(Fried), and Citri Reticulatae Pericarpium patients with the above syndromes, this medicine combined with chemotherapy can improve the effect of chemotherapy,

15 / 21

Yangtze River Pharmaceutical Group

improve the quality of life, and improve the NK cell activity, CD3, CD4/CD8 and other immune function indicators.

NERVOUS SYSTEM AGENT Product Name Main Ingredients Actions and Indications Strength Bailemian Lilii Bulbus, Acanthopanacis Senticosi Radix Et To nourish Yin and clear heat, nourish the heart and 0.27g×24c Capsules Rhizoma Seu Caulis, Polygoni Multiflori Caulis, tranquilizing. To treat indication: Insomnia (liver depression aps Albiziae Flos, Margaritifera Concha, Gypsum and Yin deficiency), with symptoms: difficulty falling asleep Fibrosum, Ziziphi Spinosae Semen, Poria , (DFA), dreaminess, festless sleep, DFA after being awake, Polygalae Radix, Scrophulariae Radix, dizziness, weakness, irritability, palpitation, restlessness, etc. Rehmanniae Radix, Ophiopogonia Radix, Schisandrae Chinensis Fructus, Junci medulla, and Salviae Miltiorrhizae Radix Et Rhizoma. With Starch as excipients.

RESPIRATORY SYSTEM AGENTS Product Name Main Ingredients Actions and Indications Strength Bushen Runfei Cordyceps Cephalosporium Mycelia Powder, Invigorating kidney and cultivating vitality, nourishing Yin and 30mL×3bo Oral Solution Lentinus Edodes, Ganoderma, Corni Fructus, moisturizing lung. For hyperlipidemia due to Qi deficiency in ttles; Cistanches Herba, Polygonati Odorati Rhizoma, lung and kidney, as well as adjuvant therapy in the 30mL×4bo and Ophiopogonis Radix convalescence of chronic bronchitis. ttles ChaiQin Baicalin, Bupleuri Radix, and Bovis Calculus Heat-clearing and detoxicating, reconciling exterior and 0.3g×12ca Qingning Artifactus. With Corn Starch as excipients. interior. For the fever with chilliness, pharyngalgia and thick ps×2plates Capsules nasal discharge and other symptoms of upper respiratory tract

16 / 21

Yangtze River Pharmaceutical Group

infection with pathogens in lung.

Children Cough Asteris Radix Et Rhizoma, Stemonae Radix, For clearing heat and moistening lung, dispersing lung-Qi, 4.5g/sachet Granules Eriobotryae Folium, Peucedani Radix, eliminating phlegm and relieving coughs. The drug is indicated ×12sachets Glycyrrhizae Radix Et Rhizoma, Armeniacae in the treatment of coughs, asthma, yellow and thick phlegm, Semen Amarum, Platycodonis Radix, Ephedrae difficult expectoration, dryness and pain in the pharynx and Herba, and Polygoni Tinctorii Folium larynx, acute and chronic tracheitis.

Lanqin Oral Isatidis Radix, Scutellariae Radix, Phellodendri For clearing heat and detoxicating, relieving sore throat and 10mL/vial Solution Chinensis Cortex, Gardeniae Fructus, and detumescence. For the treatment of symptoms as sore-throat, ×6 vials; Sterculiae Lychnophorae Semen dry throat, burning throat caused by acute pharyngitis or excess 10mL/vial heat of lung-stomach acute pharyngitis. ×12 vials

Suhuang Cough Ephedrae Herba, Perillae Folium, Pheretima, For dispelling wind and opening the inhibited lung-energy, 0.45g/cap× Capsules Honeyed Eriobotryae Folium, Roasted Perillae relieving cough and sore throat. It is indicated for coughing, 12caps/plat Fructus, Cicadae Periostracum, Peucedani Radix, pharynx itching, coughing when pharynex itching or choking e×2plates Roasted Arctii Fructus, and Schisandrae Chinensis untimely, breathlessness, or the symptom outbursts and Fructus. With Corn starch, beta cyclodextrin, aggravates when caught cold air or abnormal flavour, intenser as excipients. cough in the morning or night, which always attacks repeatedly, dry cough with no or few sputum, thin and white tongue coating, etc. caused by wind pathogen invading the lung and lung Qi obstruction; and for the treatment of cough after common cold or cough variant asthmav with above symptoms..

Xinghe Cough Mori Folium, Armeniacae Semen Amarum For relieving exterior syndrome and clearing lung, moistening 150mL/bot

17 / 21

Yangtze River Pharmaceutical Group

Syrup (prepared), Paeoniae Radix Alba, Indigo dryness and relieving cough. It is indicated for treatment of tle Naturalis, Scrophulariae Radix, Menthae coughing caused by heat injury to the lung. Symptoms: dry Haplocalycis Herba , Citri Reticulatae cough without phlegm, difficult expectoration, dry nose and Pericarpium, Platycodonis Radix and throat, thirsty and dry stool, redness of the tip and edges of the Glycyrrhizae Radix Et Rhizoma tongue, and thin tongue with little saliva.

Yinma Jiedu Lonicerae Flos, Portulacae Herba, Plantaginis Clearing heat of the organs; relieving cough and eliminating 10g/sachet Granules Herba,Rhei Radix et Rhizoma and Glycyrrhizae phlegm. Indications: pathogenic heat invading the lung. ×9sachets Radix Et Rhizoma Symptoms: coughing, occasional fever, expectoration, yellow and thick phlegm, dry mouth and pharyngalgia, headache, constipation, etc. SPECIAL DRUGS Product Name Main Ingredients Actions and Indications Strength Shuanghua Coptidis Rhizoma, Corydalis Bungeanae Herba, For clearing heat and detoxicating. It is used for light and 0.6g×24tab Baihe Tablets Rehmanniae Radix, Isatidis Radix, Arnebiae recurrent dental ulcer caused by accumulation of heart and s Radix, Lonicerae Japonicae Flos, Lophatheri spleen with the symptoms of recurrent ulcer of oral mucosa, Herba, Dry Snake Gall, Lilii Bulbus and Asari burning pain, thirst, ozostomia, red tongue with yellow coating, Radix Et Rhizoma etc.

Mingzhu Oral Cassiae Semen, Polygoni Multiflori Radix Invigorating liver and kidney, nourishing the blood and 10mL/vial Solution Praeparata, Margaritifera Concha, Chrysanthemi promoting blood circulation, eliminating dampness and ×12vials Flos, Prunellae Spica, Angelicae Sinensis Radix, improving eyesight. It is used for eyesight deterioration, tinted Paeoniae Radix Alba, Lycii Fructus, Paeoniae vision and metamorphopsy caused by Yin deficiency of liver Radix Rubra, Carthami Flos, Leonuri Herba, and kidney; and for the treatment of central serous Plantaginis Semen, Poria, Benincasae Semen, chorioretinopathy with above symptoms.

18 / 21

Yangtze River Pharmaceutical Group

Glycyrrhizae Radix Et Rhizoma

Qingruxiao Citri Reticulatae Pericarpium Viride processed Dispersing stagnated liver Qi and regulating Qi-flowing. It is 10g/sachet Granules with vinegar, Prunellae Spica, Fritillariae used for liver-depression, Qi stagnation and phlegm retention Thunbergii Bulbus, Laminariae Thallus, and with blood stasis in patients with cyclomastopathy. Symptoms: Stir-baked Olibanum with Vinegar swollen breasts, become severer before menstruation; lumps in breasts, painful when touching; fullness and stuffiness in chest and hypochondrium; irritable; thin and white tongue coating; the pulse is wiry, small and wiry, or wiry and slippery.

Xiangshao Paeoniae Radix Alba, Cyperi Rhizome, Soothing liver and regulating Qi, relieving distension and allevi 4g/sachet× Granules Toosendan Fuctus (Fried), Bupleuri Radix, ating pain, assisting in regulating stomach. Indication: (1) Prem 9sachets Chuanxiong Rhizoma, Aurantii Fructus, Pinelliae enstrual tension syndrome with hepatic Qi invasion. Symptoms: Rhizoma Praeparatum Cum Zingibere Et premenstrual restlessness and irritability, distending pain in bre Alumine, Amomi Fructus Rotundus, Aucklandiae asts, headache, insomnia and dreaminess, stomachache and dist Radix, and Glycyrrhizae Radix Et Rhizoma. With ension, gastric distending pain, nausea and vomiting, etc. (2) Cli Sucrose, Beta Cyclodextrin and Dextrin as macteric syndrome with Yin deficiency and liver hyperactivity. excipients. Symptoms: flush heat and sweating, restlessness and irritability, insomnia, palpitation, costalgia, amnesia, dizziness and tinnitus , red tongue with thin and yellow coating, wiry or deep pulse.

APIS

Product Name Specification

19 / 21

Yangtze River Pharmaceutical Group

Anastrozole In house

Dezocine In house

Dyclonine Hydrochloride In house

Edaravone In house

Epalrestat JP

Imiquimod In house

Milrinone In house

Palonosetron Hydrochloride In house

Propofol ChP

Risedronate Sodium In house

Rizatriptan Benzoate In house

Ropivacaine Mesylate In house

20 / 21

Yangtze River Pharmaceutical Group

Rupatadine Fumarate In house

Tamoxifen Citrate ChP

Trospium Chloride In house

Voriconazole In house

Zinc Acexamate ChP

Zoledronic Acid In house

Yangtze River Pharmaceutical Group Add.: 1 South Yangtze River Road, Taizhou 225321, Jiangsu Province, China Tel: 0086 523 86976882 Fax: 0086 523 86911107 E-mail: [email protected] Website: www.yangzijiang.com

21 / 21