Pharmaceutical Appendix to the Tariff Schedule 2

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Pharmaceutical Appendix to the Tariff Schedule 2

Harmonized Tariff Schedule of the United States (2008) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE Harmonized Tariff Schedule of the United States (2008) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 2 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known.

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Universidade Federal Da Paraíba Centro De Ciências Da Saúde
Universidade Federal da Paraíba Centro de Ciências da Saúde Programa de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos Wylly Araújo de Oliveira Atividade do óleo essencial de Cymbopogon winterianus Jowitt ex Bor contra Candida albicans , Aspergillus flavus e Aspergillus fumigatus João Pessoa-PB 2011 Wylly Araújo de Oliveira Atividade do óleo essencial de Cymbopogon winterianus Jowitt ex Bor contra Candida albicans , Aspergillus flavus e Aspergillus fumigatus Tese de doutorado apresentada ao Programa de Pós-Graduação em Produtos Naturais e Sintéticos Bioativos, Centro de Ciências da Saúde, Universidade Federal da Paraíba, em cumprimento aos requisitos necessários para a obtenção do título de Doutor em Produtos Naturais e Sintéticos Bioativos, área de concentração: farmacologia Orientadora: Prof.ª Dr.ª Edeltrudes de Oliveira Lima João Pessoa-PB 2011 Wylly Araújo de Oliveira Atividade do óleo essencial de Cymbopogon winterianus Jowitt ex Bor contra Candida albicans, Aspergillus flavus e Aspergillus fumigatus Tese de Doutorado aprovada em 22/06/2011 Banca examinadora ________________________________________________ Prof.ª Dr.ª Edeltrudes de Oliveira Lima Orientadora/UFPB _________________________________________________ Prof.ª Dr.ª Hilzeth de Luna Freire Pessôa - UFPB _________________________________________________ Prof. Dr. José Pinto de Siqueira Júnior - UFPB __________________________________________________ Prof.ª Dr.ª Margareth de Fátima Formiga Melo Diniz - UFPB __________________________________________________ Prof. Dr. Thompson Lopes de Oliveira - UFPB Dedicatória Com amor, dedico este trabalho à minha família: a meu pai, Francisco Claro de Oliveira; a minha mãe, Maria Araújo Filha; e a meus irmãos Kylly Araújo de Oliveira e Welly Araújo de Oliveira. Sem o apoio deles, nada disso teria sido possível. Apesar da ausência, eles sempre estiveram no meu coração.
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CAUTION Or Streams with the Product Or Used Containers
PROTECTION OF WILDLIFE, FISH, CRUSTACEANS AND THE ENVIRONMENT Abamectin is extremely toxic to aquatic species. DO NOT contaminate dams, rivers CAUTION or streams with the product or used containers. KEEP OUT OF REACH OF CHILDREN FIRST AID READ SAFETY DIRECTIONS BEFORE OPENING OR USING If poisoning occurs contact a doctor or the Poisons Info Centre. Phone Australia FOR ANIMAL TREATMENT ONLY 13 11 26; New Zealand 0800 764 766. If skin contact occurs, remove contaminated clothing and wash skin thoroughly. ® SAFETY DIRECTIONS EQUITAK EXCEL ORAL PASTE HARMFUL IF SWALLOWED. May irritate the eyes and skin; avoid contact with eyes 3 in 1 Wormer for Horses and skin. Repeated exposure may cause allergic disorders. When opening the container and using the product, wear rubber gloves. Wash hands after use. DESCRIPTION EMERGENCY RESPONSE A pale cream to tan coloured, apple flavoured, palatable paste with a characteristic In case of spillage wear appropriate protective clothing and prevent material from odour and taste. Each gram contains Oxfendazole 200mg, Praziquantel 50mg and entering waterways. Absorb spills with inert material and place in waste containers. Abamectin 4mg. Wash the area with water and absorb with further inert material. Dispose of waste safely. MODE OF ACTION Abamectin stimulates the release of the neurotransmitter GABA in roundworms, MEAT WITHHOLDING PERIOD (HORSES): DO NOT USE less than 28 days which increases the membrane permeability of neurons to chloride ions. Normal before slaughter for human consumption. neural transmission is thus inhibited causing paralysis and death of the parasite. STORAGE Praziquantel affects the attachment of tapeworms to the host tissues by causing Store below 30°C (room temperature), tightly closed, in the original syringe and in spastic paralysis.
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View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by D-Scholarship@Pitt Ottilie et al. J Cheminform (2018) 10:6 https://doi.org/10.1186/s13321-018-0261-3 RESEARCH ARTICLE Open Access Two inhibitors of yeast plasma membrane ATPase 1 (ScPma1p): toward the development of novel antifungal therapies Sabine Ottilie1†, Gregory M. Goldgof1,4†, Andrea L. Cheung1, Jennifer L. Walker2, Edgar Vigil1, Kenneth E. Allen3, Yevgeniya Antonova‑Koch1, Carolyn W. Slayman3^, Yo Suzuki4 and Jacob D. Durrant2* Abstract Given that many antifungal medications are susceptible to evolved resistance, there is a need for novel drugs with unique mechanisms of action. Inhibiting the essential proton pump Pma1p, a P-type ATPase, is a potentially efective therapeutic approach that is orthogonal to existing treatments. We identify NSC11668 and hitachimycin as structur‑ ally distinct antifungals that inhibit yeast ScPma1p. These compounds provide new opportunities for drug discovery aimed at this important target. Keywords: Antifungal, PMA1, P-type ATPase, Computer modeling, Saccharomyces cerevisiae, In vitro evolution, Drug resistance Background sterol-C-24-methyltransferase and the fungal cell mem- Antifungal medications are in high demand, but low brane directly [8]. efcacy, host toxicity, and emerging resistance among Only a few approved antimycotics have mecha- clinical strains [1, 2] complicate their use. Tere is an nisms that are unrelated to ergosterol biosynthesis. urgent need for novel antimycotic therapeutics with For example, the highly efective echinocandins inhibit unique mechanisms of action. Te purpose of the cur- 1,3-β-glucan synthase, hindering production of the criti- rent work is to describe two novel antifungals: 4-N,6- cal cell-wall component β-glucan [9, 10]; and the terato- N-bis(3-chlorophenyl)-1-methylpyrazolo[3,4-d] genic compound fucytosine interferes with eukaryotic pyrimidine-4,6-diamine (NSC11668), and hitachimycin RNA/DNA synthesis [11, 12].
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)&F1y3x PHARMACEUTICAL APPENDIX to THE
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