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Pure Appl. Chem., Vol. 72, No. 3, pp. 479–552, 2000. © 2000 IUPAC

INTERNATIONAL FEDERATION OF CLINICAL CHEMISTRY AND LABORATORY MEDICINE

SCIENTIFIC DIVISION COMMITTEE ON NOMENCLATURE, PROPERTIES, AND UNITS (C-NPU)#

and

INTERNATIONAL UNION OF PURE AND APPLIED CHEMISTRY

CHEMISTRY AND HUMAN HEALTH DIVISION CLINICAL CHEMISTRY SECTION COMMISSION ON NOMENCLATURE, PROPERTIES, AND UNITS (C-NPU)§

PROPERTIES AND UNITS IN THE CLINICAL LABORATORY SCIENCES PART XII. PROPERTIES AND UNITS IN CLINICAL AND TOXICOLOGY

(Technical Report)

(IFCC–IUPAC 1999)

Prepared for publication by HENRIK OLESEN1, DAVID COWAN2, RAFAEL DE LA TORRE3 , IVAN BRUUNSHUUS1, MORTEN ROHDE1, and DESMOND KENNY4

1Office of Laboratory Informatics, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark; 2Drug Control Centre, London University, King’s College, London, UK; 3IMIM, Dr. Aiguader 80, Barcelona, Spain; 4Dept. of Clinical Biochemistry, Our Lady’s Hospital for Sick Children, Crumlin, Dublin 12, Ireland

#§The combined Memberships of the Committee and the Commission (C-NPU) during the preparation of this report (1994–1996) were as follows: Chairman: H. Olesen (Denmark, 1989–1995); D. Kenny (Ireland, 1996); Members: X. Fuentes-Arderiu (Spain, 1991–1997); J. G. Hill (, 1987–1997); D. Kenny (Ireland, 1994–1997); H. Olesen (Denmark, 1985–1995); P. L. Storring (UK, 1989–1995); P. Soares de Araujo (Brazil, 1994–1997); R. Dybkær (Denmark, 1996–1997); C. McDonald (USA, 1996–1997).

Please forward comments to: H. Olesen, Office of Laboratory Informatics 76-6-1, Copenhagen University Hospital (Rigshospitalet), 9 Blegdamsvej, DK-2100 Copenhagen, Denmark. E-mail: [email protected]

Republication or reproduction of this report or its storage and/or dissemination by electronic means is permitted without the need for formal IUPAC permission on condition that an acknowledgment, with full reference to the source, along with use of the copyright symbol ©, the name IUPAC, and the year of publication, are prominently visible. Publication of a translation into another language is subject to the additional condition of prior approval from the relevant IUPAC National Adhering Organization. 479 480 H. OLESEN

Properties and units in the clinical laboratory sciences. Part XII. Properties and units in clinical pharmacology and toxicology (Technical Report)

Abstract: The term designating a substance being an active ingredient of a may be a generic name, a nonproprietary name, a registered trade name, a fantasy name, or other. This causes difficulties in the transmission of requests and reports on properties for such substances in biological fluids to and from the clinical laboratories, and in the collating of this information from different sources. The document comprises a list of properties of in biological fluids for use in electronic transmission systems. Systematic names are presented together with a code value for each.

PREFACE The present document is part twelve (XII) of a series on properties and units in the clinical laboratory sciences initiated in 1987. The series will comprise:

I. Syntax and semantic rules [1] II. Kinds-of-property [2] III. Elements (of properties) and their code values IV. Properties and their code values V. Properties and units in thrombosis and haemostasis VI. Properties and units in IOC-prohibited drugs VII. Properties and units in inborn errors of VIII. Properties and units in clinical microbiology IX. Properties and units in trace elements X. Properties and units in general clinical chemistry XI. Coding systems: structure and guidelines [3] XII. Properties and units in clinical pharmacology and toxicology (this report) XIII. Properties and units in reproduction and fertility XVI. Properties and units in clinical allergology

The size and complexity of parts III and IV are such that their lists will be presented in electronic format. This is for ease of handling and to facilitate expression of concepts in different languages. At the end, systematic names, elaborated according to international standards and recommenda- tions, should be available in the different domains of clinical laboratory sciences. The core of the series is code value strings representing concepts, that in combination delineate and define each property regardless of linguistic expression, thus avoiding errors during translation between languages.

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 481

FOREWORD AND SCOPE Clinical laboratory sciences are characterized by the exacting nature of the work performed and the demand for an accurate presentation of the outcome. Furthermore, the domain is transnational, international, or “global”. The adherent informatics system therefore needs to identify the findings accurately and to present them with the degree of detail required. At the same time it has to facilitate the transfer over linguistic and cultural barriers without distortion or loss of clarity, in order to promote clear, unambiguous, mean- ingful, and fully informative communication in different terminologies. The degree to which a message (such as a laboratory report) needs to be expressed in a formal, systematic language depends on the geographical, linguistic, social or professional distance between the communicating parties. The greater the distance, the greater the risk of misunderstanding. Within one laboratory, local jargon terms may be used which are usually well understood be- tween colleagues, but which would not be sufficiently widely known for communication with the out- side world. Likewise, a laboratory and its local community of users, such as hospital or community physicians, may use a “local dialect” of the language of clinical laboratory sciences which is well understood by all concerned; but when the communication possibilities are wider, even transnational, risks of serious misunderstanding arise. The purpose of this document is to apply the IFCC–IUPAC recommended syntax structures for request and report and to create a systematic terminology that can be used as the basis for encoding laboratory messages in the domain of drugs. The systamatic names recommended here are primarily for the purpose of unambiguous data exchange. Their use in routine language by clinician or laboratory practitioners is optional but encouraged.

DEFINITIONS component definable part of a system [ENV 1614; 4] EXAMPLE: as part of a plasma sample discrimination value value of a quantity established from purpose related considerations NOTE: The term cut-off value is used as a synonym. detection limit result of a measurement by a given measurement procedure for which the probability of an analytically false negative result is b, given the probability a of an analytically false positive result [5] drug substance which when absorbed into a living organism may modify one or more of its functions [6] NOTE: The term is generally accepted for a substance taken for a therapeu- tic purpose, but is also commonly used for abused substances. kind-of-property attribute of phenomena, bodies or substances that may distinguished qualitatively [after ENV 1614; 4] NOTE 1: In ENV 1614 the term “property” (in a general sense) is used as a synonym for kind-of-property. NOTE 2: A kind-of-property may be related to nominal scale (e.g., green; blue), ordinal scale (e.g., small; large), difference scale [e.g., 10 °C (i.e., 10 °C more than an arbitrary zero)] or ratio scale (length 2 m or 5 m); the last two types of kind-of-property are also called kind-of-quantity.

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 482 H. OLESEN nominal scale scale with a set of possible values for a given kind-of-property that are each a word or symbol without any relation to magnitude [5] EXAMPLE: Names of drugs. NOTE: The values may be listed in any arbitrary order according to practical considerations and convention. ordinal scale scale with an ordered set of possible values for a given kind-of-property that are each a word or symbol used for ranking according to magnitude, but where differences or ratios between values have no arithmetic meaning [5] EXAMPLE: arbitrary concentration of in (“not de- tected”; “detected” or 0 1). difference scale scale with an ordered set of possible values of a given kind of measurable quantity that are each a product of numerical value and unit of measurement such that a given difference between values corresponds to the same difference between magnitudes of the measurable quantities along the scale [5] EXAMPLE: (substance concentration increment) –32 µmol/l property set of data elements comprising information on system, component, and kind-of-property and their adherent specifications. NOTE 1: There is presently no officially approved definition of this concept. The present definition is for use in this document only. NOTE 2: Information about identification of system, time, and result is not considered. EXAMPLE: substance concentration of in . ratio scale scale of measurement with an ordered set of values for a given kind of measurable quantity that are each a product of numerical value and unit of measurement such that a given ratio between values corresponds to the same ratio between magnitudes of the measurable quantities along the scale [5] EXAMPLE: 0 0,1 0,2 - - - 31 32 µmol/l. system demarcated arrangement of a set of elements and a set of relationships between these elements [ENV 1614; 4]. EXAMPLE: a portion of urine, a portion of blood.

SYSTEMATIC REQUEST AND REPORT OF CLINICAL LABORATORY RESULTS By convention, properties and results of examinations are represented by the equation:

Equation 1 Property = Result

The parts comprised in the concept of ‘property’ and in the concept of ‘result’ are presented in Table 1.

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 483

Table 1 Systematic request and report.

1 Identification and time 1.1 Object or patient identification 1.2 Date and time(s) of sampling

2 Property 2.1 System 2.2 Component 2.3 Kind-of-property

3 Result 3.1 Equality, inequality or other operator 3.2 Value (for quantities on a difference or ratio scale, a numerical value multiplied by a unit)

4 Notes

• Essential for a request is parts 1 and 2, that is information on patient identification, time or time interval for sampling, and information on the property requested. • The laboratory report on a particular property comprises the three parts 1, 2, and 3. • To each element in part 2 may be added a specification as a parenthetic suffix for clarification, identification, and to avoid ambiguity. • Note(s) (part 4) relating to, for example, diagnosis, , haemolysis, or hardware break- down are not included, except when needed for the interpretation of results such as pretreatment of patient or subject. • Thus, the elements of a term for a type of property comprise: System(specification)— Component(specification); kind-of-property(specification) • This is as recommended by IFCC and IUPAC (3) and by the European standard ENV 1614:1995 [4]. • EXAMPLE [NPU02164] Plasma—Gentamicin; substance concentration • The elements of a result comprise: an operator (= < £ > ≥ etc.), a numerical value and a unit, usually in symbolic form. This is as recommended by the European standard ENV 12435:1996 [7] • EXAMPLE [NPU02164] = 6 µmol/l (prefix µ: micro = 10–6) • Nominal and ordinal scale values carry no unit. In difference and ratio scales the unit must never be omitted in reporting results, except for the unit 1. • It is further recommended that the result includes or refers to a value for a measure of uncertainty [7]. • The names of components are from the International Nonproprietary Names (INN) of WHO [8] for pharmaceutical substances (English, French, Russian and Spanish). If not recorded in INN, preference is for CAS trivial names [9], USAN [10], BAN [11], Martindale [12], in that sequence. • In addition to the systematic name of the property, an example and other useful information are given.

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 484 H. OLESEN

For details, see IUPAC–IFCC (Recommendations 1995). Syntax and semantic rules [1]. Most drugs are metabolized by the organism. Therefore, the analytical findings pertain to the drug administered and to its metabolites. Often the non-modified drug is hardly detectable. If so, the result given to the requester is on the parent compound in the form of a result deduced from the presence of specific metabolites. Information on metabolites found is part of the report and is given after a “deduced from”.

ELEMENTS OF AN ENTRY The terms recommended are given in bold, that is: the systematic term for the type of property, the unit and the code value. 1. Name of system and parenthetic specification spelled out in full, and followed by a long dash (em dash). 2. Alphanumeric chemical prefixes to component name. 3. Recommended name of component and parenthetic specification. Shifted to the left for al- phabetical sorting and searching, and followed by a semicolon. 4. Kind-of-property and parenthetic specification. 5. Unit. 6. Other term(s). 7. Authority: Code value for the international organization recommending the name of the compo- nent or the combined elements of an entry. 8. Note(s) with any further information. 9. [NPUXXXXX] Coding scheme identifier and code value, intended for interlaboratory transmission between databases. 10. Example in abbreviated form. The term “arbitrary” in princible cannot be related to a volume. In clinical chemistry, however, a less well defined “inhouse” or a regional calibrator is often referred to and is expressed in “arbitrary unit per liter” in order to enable comparison of patient data over time and regionally. In each of these in- stances further information should be given in the parenthesis “procedure”. This could be information on the calibrator used, f.ex. “BCR/CRM148/149R“ or it could refer to the inlaboratory document “procedure xx”, which is available on request. In the examples given, a question mark, “?”, has been used to represent the value of a result for properties including quantities.

EXAMPLES a. Nominal scale

1. Urine— 3. Analgesic drug; 4. taxon(procedure) 9. [NPU04479] 10. U—Analgesic drug; taxon(Firm xxx) = ; Dextropropoxyphene

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 485

1. Urine— 3. Narcotic drug; 4. taxon(procedure) 9. [NPU08930] 10. U—Narcotic drug; taxon(Firm xxx) = deduced from Benzoylecgonine (CAS519-09-5) Ecgonine (CAS481-37-8) b. Ordinal scale In the actual reporting the possible scale values should be listed in the parenthesis after the kind-of-property.

1. Urine— 3. Analgesic drug; 4. arbitrary concentration(list; procedure) 9. [NPU04845] 10. U—Analgesic drug; arb.c.(list; 0 1) [NPU04934] U—Alphaprodine; arb.c.(0 1) = 0 [NPU04401] U—; arb.c.(0 1) = 0 [NPU04584] U—Buprenorphine; arb.c.(0 1) = 1 [NPU01710] U—; arb.c.(0 1) = 0 [NPU04916] U—; arb.c.(0 1) = 0 [NPU01866] U—Dextropropoxyphene; arb.c.(0 1) = 1 [NPU04450] U—Diamorphine; arb.c.(0 1) = 0 [NPU04454] U—; arb.c.(0 1) = 0 [NPU04463] U—; arb.c.(0 1) = 0 [NPU04464] U—; arb.c.(0 1) = 0 [NPU02032] U—Fentanyl; arb.c.(0 1) = 0 [NPU02408] U—; arb.c.(0 1) = 0 [NPU02523] U—; arb.c.(0 1) = 0 [NPU04497] U—; arb.c.(0 1) = 0 [NPU02722] U—; arb.c.(0 1) = 0 [NPU02846] U—(non-complexed); arb.c.(0 1) = 0 [NPU04536] U—; arb.c.(0 1) = 0 [NPU04591] U—; arb.c.(0 1) = 0 [NPU04596] U—; arb.c.(0 1) = 0 [NPU03035] U—; arb.c.(0 1) = 0 [NPU03049] U—; arb.c.(0 1) = 0 [NPU04599] U—; arb.c.(0 1) = 0 [NPU03384] U—Salicylate; arb.c.(0 1) = 0 [NPU04549] U—; arb.c.(0 1) = 0 [NPU04647] U—Trimeperidine; arb.c.(0 1) = 0

1. Urine— 3. Cocaine; 4. arbitrary concentration(procedure)

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 486 H. OLESEN

7. Authority: BAN 9. [NPU01706] 10. U—Cocaine; arb.c.(0 1) = 1 deduced from Benzoylecgonine (CAS519-09-5) Ecgonine (CAS481-37-8)

c. Ratio scale

1. Plasma— 3. Fentanyl; 4. substance concentration 5. nanomole/liter 9. [NPU08918] 10. P—Fentanyl; subst.c. = ? nmol/l

REFERENCES 1. Commission/Committee on Quantities and Units (in Clinical Chemistry) of the IUPAC–IFCC (International Union of Pure and Applied Chemistry– International Federation of Clinical Chemistry). Properties and units in the clinical laboratory sciences. I. Syntax and semantic rules. Prepared for publication by H. Olesen. Pure Appl. Chem. 67, 1563–74 (1995); Eur. J. Clin. Chem. Clin. Biochem. 33, 627–36 (1995); Clin. Chim. Acta 245, S5–S21 (1996). 2. Commission/Committee on Quantities and Units (in Clinical Chemistry) of the IUPAC–IFCC (International Union of Pure and Applied Chemistry–International Federation of Clinical Chemistry). Properties and units in the clinical laboratory sciences. II. Kinds-of-property. Prepared for publication by D. Kenny and H. Olesen. Eur. J. Clin. Chem. Clin. Biochem. 35, 317–44 (1997). 3. Commission/Committee on Nomenclature, Properties and Units of the IUPAC–IFCC (International Union of Pure and Applied Chemistry–International Federation of Clinical Chemistry). Properties and units in the clinical laboratory sciences. XI. Coding systems—structure and guidelines. (Technical report 1997). Prepared for publication by H. Olesen, D. Kenny, R. Dybkær, I. Ibsen, I. Bruunshuus, X. Fuentes-Arderiu, G. Hill, P. Soares de Araujo, C. McDonald. Pure Appl. Chem. 35, 317–44 (1997). 4. CEN/TC 251,1995. European Prestandard ENV 1614. Medical informatics. Structure for nomenclature, classification and coding of properties in clinical laboratory sciences. 5. R. Dybkaer. Eur. J. Clin. Chem. Clin. Biochem. 35 (2), 141–73 (1997). 6. J. H. Duffus. Pure and Appl. Chem. 65, 2003–2122 (1993). 7. CEN/TC 251, 1996. European Prestandard, ENV 12435. Medical informatics. Expression of the results of measurement in health sciences. 8. WHO. International Nonproprietary Names (INN) for Pharmaceutical Substances. Geneva: WHO. 9. CAS Registry Number. 10. USAN (U.S. Adopted Name). 1961–1987 Cumulative List. List 147-289. 11. BAN (British Approved Names) booklet, 1986, 1st, 2nd, 3rd, and 4th supplements. 12. E. F. Reynolds (Ed.). Martindale. The Extra Pharmacopoeia, 31st ed., London, The Pharmaceutical Press (1996).

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 487

INDEX OF ABBREVIATIONS BAN British Approved Name CAS Chemical Abstracts Service IFCC International Federation of Clinical Chemistry and Laboratory Medicine INN International Nonproprietary Names of WHO (approved) *INN for name to be approved ISO International Organization for Standardization IUPAC International Union of Pure and Applied Chemistry USAN Adopted Name WHO World Health Organization

LIST OF PROPERTIES IN PHARMACOLOGY AND TOXICOLOGY

Urine— Urine— ; ; arbitrary concentration(procedure) substance concentration M = 336,43 g/mol micromole/liter NPU04576 M = 326,47 g/mol U—Acebutolol; arb.c.(proc.) = ? NPU04329 U—Acepromazine; subst.c. = ? µmol/l Urine— Acebutolol; Urine— substance concentration ; micromole/liter arbitrary concentration(procedure) M = 336,43 g/mol M = 222,25 g/mol NPU01003 NPU08917 U—Acebutolol; subst.c. = ? µmol/l U—Acetazolamide; arb.c.(proc.) = ?

Plasma— Plasma— Acecainide; Acetazolamide; substance concentration substance concentration micromole/liter micromole/liter NPU10765 M = 222,25 g/mol P—Acecainide; subst.c. = ? µmol/l NPU04624 P—Acetazolamide; subst.c.= ? µmol/l Urine— Acepromazine; Urine— arbitrary concentration(procedure) Acetazolamide; M = 326,47 g/mol substance concentration NPU04328 micromole/liter U—Acepromazine; arb.c.(proc.) = ? M = 222,25 g/mol NPU01009 Plasma— U—Acetazolamide; subst.c. = ? µmol/l Acepromazine; substance concentration micromole/liter M = 326,47 g/mol NPU01004 P—Acepromazine; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 488 H. OLESEN

Urine— Urine— beta-antagonist; ; arbitrary concentration(list; procedure) substance concentration Other term(s): Beta-Antagonist, adrenergic; mole/liter Beta- blockader; Beta- M = 416,52 g/mol Adrenergic blocking agent; Beta-blocker, NPU04331 adrenergic; Beta-blocking drug U—Alfentanil; subst.c.= ? prefix ? mol/l NPU04413 U—Adrenergic beta-antagonist; arb.c.(list; Plasma— proc.) ; NPU04576 U—Acebutolol; arb.c.(proc.) = ? substance concentration NPU04577 U—; arb.c.(proc.) = ? nanomole/liter NPU04579 U—; arb.c.(proc.) = ? NPU08965 NPU04405 U—; arb.c.(proc.) = ? P—Alimemazine; subst.c. = ? nmol/l NPU04406 U—; arb.c.(proc.) = ? NPU04407 U—; arb.c.(proc.) = ? Urine— NPU04962 U—; arb.c.(proc.) = ? Allopurinol; NPU04960 U—; arb.c.(proc.) = ? arbitrary concentration(procedure) NPU04961 U—Bunolol; arb.c.(proc.) = ? M = 136,11 g/mol NPU14146 U—; arb.c.(proc.) = ? NPU04332 NPU04697 U—; arb.c.(proc.) = ? U—Allopurinol; arb.c.(proc.) = ? NPU04503 U—; arb.c.(proc.) = ? NPU04616 U—; arb.c.(proc.) = ? Plasma— NPU04555 U—; arb.c.(proc.) = ? Allopurinol; NPU04542 U—; arb.c.(proc.) = ? substance concentration NPU04620 U—; arb.c.(proc.) = ? mole/liter NPU04621 U—; arb.c.(proc.) = ? M = 136,11 g/mol NPU04626 U—; arb.c.(proc.) = ? NPU04334 NPU03231 U—; arb.c.(proc.) = ? P—Allopurinol; subst.c.= ? prefix ? mol/l NPU03266 U—; arb.c.(proc.) = ? NPU08674 U—; arb.c.(proc.) = ? Urine— NPU14147 U—; arb.c.(proc.) = ? Allopurinol; NPU04629 U—; arb.c.(proc.) = ? substance concentration mole/liter Urine— M = 136,11 g/mol Adrenergic beta-antagonist; NPU04333 taxon(procedure) U—Allopurinol; subst.c.= ? prefix ? mol/l Other term(s): Beta-Antagonist, adrenergic; Beta-Adrenergic receptor blockader; Beta- Urine— Adrenergic blocking agent; Beta-blocker, Alphaprodine; adrenergic; Beta-blocking drug arbitrary concentration(procedure) NPU04414 M = 261,35 g/mol U—Adrenergic beta-antagonist; taxon Other term(s): Alphaprodine (proc.)=? NPU04934 U—Alphaprodine; arb.c.(proc.) = ? Urine— Alfentanil; Urine— arbitrary concentration(procedure) Alphaprodine; M = 416,52 g/mol substance concentration NPU04330 micromole/liter U—Alfentanil; arb.c.(proc.) = ? M = 261,35 g/mol Other term(s): Alphaprodine Plasma— NPU01150 Alfentanil; U—Alphaprodine; subst.c. = ? µmol/l substance concentration mole/liter M = 416,52 g/mol NPU04554 P—Alfentanil; subst.c.= ? prefix ? mol/l

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Urine— Urine— ; Amfebutamone; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 308,77 g/mol M = 239,74 g/mol NPU01151 NPU04344 U—Alprazolam; arb.c.(proc.) = ? U—Amfebutamone; arb.c.(proc.) = ?

Urine— Plasma— Alprazolam; Amfebutamone; substance concentration substance concentration micromole/liter mole/liter M = 308,77 g/mol M = 239,74 g/mol NPU04335 Other term(s): U—Alprazolam; subst.c. = ? µmol/l NPU04346 P—Amfebutamone; subst.c.= ? prefix ? mol/l Plasma— Alprazolam; Urine— substance concentration Amfebutamone; nanomole/liter substance concentration M = 308,77 g/mol mole/liter NPU04627 M = 239,74 g/mol P—Alprazolam; subst.c.= ? nmol/l NPU04345 U—Amfebutamone; subst.c.= ? prefix ? mol/l Urine— Alprenolol; Urine— arbitrary concentration(procedure) ; M = 249,35 g/mol arbitrary concentration(procedure) NPU04577 M = 205,30 g/mol U—Alprenolol; arb.c.(proc.) = ? Other term(s): Diethylpropion NPU01162 Urine— U—Amfepramone; arb.c.(proc.) = ? Alprenolol; substance concentration Urine— micromole/liter Amfepramone; M = 249,35 g/mol substance concentration NPU01154 micromole/liter U—Alprenolol; subst.c. = ? µmol/l M = 205,30 g/mol Other term(s): Diethylpropion Plasma— NPU01161 ; U—Amfepramone; subst.c. = ? µmol/l substance concentration micromole/liter Urine— M = 151,26 g/mol Amfetamine; NPU04336 arbitrary concentration(procedure) P—Amantadine; subst.c. = ? µmol/l M = 135,20 g/mol Other term(s): Urine— NPU01163 Amantadine; U—Amfetamine; arb.c.(proc.) = ? substance concentration micromole/liter Urine— M = 151,26 g/mol Amfetamine; NPU04337 substance concentration U—Amantadine; subst.c. = ? µmol/l micromole/liter M = 135,20 g/mol Urine— Other term(s): Amphetamine Amdinocillin; NPU01166 arbitrary concentration(procedure) U—Amfetamine; subst.c. = ? µmol/l M = 325,43 g/mol NPU10187 U—Amdinocillin; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 490 H. OLESEN

Urine— Plasma— Amfetamine+analogue; ; arbitrary concentration(procedure) substance concentration Note: d-Amfetamine; d,l-Amfetamine; d,l- micromole/liter ; ;Nylidrin; M = 229,65 g/mol ; ; NPU04773 P—Amiloride; subst.c.= ? µmol/l NPU08960 U—Amfetamine+analogue; arb.c.(proc.) = ? Urine— Amiloride; Urine— substance concentration Amfetamine+analogue; micromole/liter taxon(procedure) M = 229,65 g/mol Note: Amfetamine; Ephedrine; ; NPU01172 Metamfetamine; 3,4- U—Amiloride; subst.c. = ? µmol/l Methylenedioxyamfetamine; 3,4- Metylenedioxymetamfetamine; 3,4- Urine— Metylenedioxymetamfetamine; ; substance concentration NPU08980 mole/liter U—Amfetamine+analogue; taxon(proc.) = ? M = 337,47 g/mol NPU04918 Urine— U—Amineptine; subst.c.= ? prefix ? mol/l ; arbitrary concentration(procedure) Plasma— M = 250,33 g/mol ; Other term(s): Amphetaminil substance concentration(list; procedure) NPU04913 NPU17592 U—Amfetaminil; arb.c.(proc.) = ? P—Amiodarone; subst.c.(list; proc.) NPU01219 P—Amiodarone; subst.c. = ? µmol/l Urine— NPU01220 P—Amiodarone+Desethylamiodarone; Amfetaminil; subst.c. = ? µmol/l substance concentration NPU08618 P—Desethylamiodarone; subst.c. micromole/liter = ? µmol/l M = 250,33 g/mol Other term(s): Amphetaminil Plasma— NPU01169 Amiodarone; U—Amfetaminil; subst.c. = ? µmol/l substance concentration micromole/liter Plasma— M = 645,32 g/mol Amikacin; NPU01219 arbitrary concentration(procedure) P—Amiodarone; subst.c. = ? µmol/l NPU12398 P—Amikacin; arb.c.(proc.) = ? Plasma— Amiodarone+Desethylamiodarone; Plasma— substance concentration Amikacin; micromole/liter arbitrary substance concentration(procedure) NPU01220 arbitrary unit/liter P—Amiodarone+Desethylamiodarone; NPU10012 subst.c. = ? µmol/l P—Amikacin; arb.subst.c.(proc.) = ? arb.unit/l Urine— Plasma— ; Amikacin; arbitrary concentration(procedure) substance concentration M = 191,26 g/mol mole/liter NPU04919 NPU10013 U—Amiphenazole; arb.c.(proc.) = ? P—Amikacin; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 491

Urine— Urine— Amiphenazole; ; substance concentration substance concentration micromole/liter nanomole/liter M = 191,26 g/mol M = 313,79 g/mol NPU01223 NPU04508 U—Amiphenazole; subst.c. = ? µmol/l U—Amoxapine; subst.c.= ? nmol/l

Urine— Plasma— ; Amoxapine+metabolite; arbitrary concentration(procedure) substance concentration M = 277,39 g/mol nanomole/liter NPU04771 Note: 7-Hydroxyamoxapine; 8- U—Amitriptyline; arb.c.(proc.) = ? Hydroxyamoxapine NPU09347 Plasma— P—Amoxapine+metabolite; subst.c. = ? nmol/l Amitriptyline; substance concentration Urine— nanomole/liter ; M = 277,39 g/mol arbitrary concentration(procedure) NPU01224 M = 365,41 g/mol P—Amitriptyline; subst.c. = ? nmol/l NPU08758 U—Amoxicillin; arb.c.(proc.) = ? Urine— Amitriptyline; Plasma— substance concentration Amoxicillin; nanomole/liter substance concentration M = 277,39 g/mol micromole/liter NPU04772 M = 365,41 g/mol U—Amitriptyline; subst.c.= ? nmol/l NPU08757 P—Amoxicillin; subst.c. = ? µmol/l Plasma— Amitriptyline+; Urine— substance concentration Amoxicillin; nanomole/liter substance concentration Note: M (amitriptyline) = 277,39 g/mol; micromole/liter M (nortriptyline) = 263,4 g/mol M = 365,41 g/mol NPU03927 NPU08759 P—Amitriptyline+Nortriptyline; subst.c. = ? U—Amoxicillin; subst.c.= ? µmol/l nmol/l Cerebrospinal fluid— Urine— Amphotericin B; Amoxapine; substance concentration arbitrary concentration(procedure) micromole/liter M = 313,79 g/mol NPU12943 NPU01229 Csf—Amphotericin B; subst.c. = ? µmol/l U—Amoxapine; arb.c.(proc.) = ? Plasma— Plasma— Amphotericin B; Amoxapine; substance concentration substance concentration micromole/liter nanomole/liter NPU12945 M = 313,79 g/mol P—Amphotericin B; subst.c. = ? µmol/l NPU01228 P—Amoxapine; subst.c. = ? nmol/l Secretion(specification)— Amphotericin B; substance concentration micromole/liter NPU12944 Secr(spec.)—Amphotericin B; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 492 H. OLESEN

Urine— Urine— Amphotericin B; Anileridine; substance concentration arbitrary concentration(procedure) micromole/liter M = 352,46 g/mol NPU12946 NPU04401 U—Amphotericin B; subst.c. = ? µmol/l U—Anileridine; arb.c.(proc.) = ?

Urine— Urine— Ampicillin; Anileridine; arbitrary concentration(procedure) substance concentration M = 349,41 g/mol micromole/liter NPU10275 M = 352,46 g/mol U—Ampicillin; arb.c.(proc.) = ? NPU01261 U—Anileridine; subst.c. = ? µmol/l Urine— Analgesic drug; System(specification)— arbitrary concentration(list; procedure) agent; NPU04845 taxon(procedure) U—Analgesic drug; arb.c.(list; proc.) NPU10279 NPU04934 U—Alphaprodine; arb.c.(proc.) = ? Syst(spec.)—Anorectic agent; taxon(proc.) = ? NPU04401 U—Anileridine; arb.c.(proc.) = ? NPU04584 U—Buprenorphine; arb.c. Urine— (proc.) = ? ; NPU01710 U—Codeine; arb.c.(proc.) = ? arbitrary concentration(procedure) NPU04916 U—Dextromoramide; arb.c.(proc.) = ? M = 265,36 g/mol NPU01866 U—Dextropropoxyphene; arb.c. NPU01269 (proc.) = ? U—Antazoline; arb.c.(proc.) = ? NPU04450 U—Diamorphine; arb.c.(proc.) = ? NPU04454 U—Dipipanone; arb.c.(proc.) = ? Urine— NPU04463 U—Ethoheptazine; arb.c.(proc.) = ? Antazoline; NPU04464 U—Ethylmorphine; arb.c.(proc.) = ? substance concentration NPU02032 U—Fentanyl; arb.c.(proc.) = ? micromole/liter NPU02408 U—Hydrocodone; arb.c.(proc.) = ? M = 265,36 g/mol NPU02523 U—Ketobemidone; arb.c.(proc.) = ? NPU04776 NPU04497 U—Levorphanol; arb.c.(proc.) = ? U—Antazoline; subst.c. = ? µmol/l NPU02722 U—Methadone; arb.c.(proc.) = ? NPU02846 U—Morphine(non-complexed); Plasma— arb.c.(proc.) = ? Antidepressive drug, ; NPU04536 U—Nalbuphine; arb.c.(proc.) = ? arbitrary concentration(procedure) NPU04591 U—Oxycodone; arb.c.(proc.) = ? NPU14177 NPU04596 U—Paracetamol; arb.c.(proc.) = ? P—Antidepressive drug, tricyclic; arb.c.(proc.) = ? NPU03035 U—Pentazocine; arb.c.(proc.) = ? NPU03049 U—Pethidine; arb.c.(proc.) = ? Urine— NPU04599 U—Phenazocine; arb.c.(proc.) = ? Antidepressive drug, tricyclic; NPU03384 U—Salicylate; arb.c.(proc.) = ? arbitrary concentration(procedure) NPU04549 U—Tramadol; arb.c.(proc.) = ? NPU10006 NPU04647 U—Trimeperidine; arb.c.(proc.) = ? U—Antidepressive drug, tricyclic; arb.c.(proc.) = ?

System(specification)— Analgesic drug; taxon(procedure) NPU10278 Syst(spec.)—Analgesic drug; taxon(proc.) = ?

Urine— Analgesic drug; taxon(procedure) NPU04479 U—Analgesic drug; taxon(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 493

Urine— Plasma— Antidepressive drug; Azithromycin; arbitrary concentration(list; procedure) substance concentration NPU04824 mole/liter U—Antidepressive drug; arb.c.(list; proc.) M = 748,99 g/mol NPU04771 U—Amitriptyline; arb.c.(proc.) = ? NPU08773 NPU01229 U—Amoxapine; arb.c.(proc.) = ? P—Azithromycin; subst.c.= ? prefix ? mol/l NPU04784 U—; arb.c.(proc.) = ? NPU01617 U—; arb.c.(proc.) = ? Urine— NPU01859 U—; arb.c.(proc.) = ? ; NPU04793 U—; arb.c.(proc.) = ? arbitrary concentration(procedure) NPU01925 U—; arb.c.(proc.) = ? M = 184,19 g/mol NPU02473 U—; arb.c.(proc.) = ? NPU01343 NPU02688 U—; arb.c.(proc.) = ? U—Barbital; arb.c.(proc.) = ? NPU02816 U—; arb.c.(proc.) = ? NPU02924 U—Nortriptyline; arb.c.(proc.) = ? Plasma— Barbital; Plasma— substance concentration Antidepressive drug; micromole/liter substance concentration(list) M = 184,19 g/mol NPU16406 NPU10139 P—Antidepressive drug; subst.c.(list) P—Barbital; subst.c. = ? µmol/l NPU01224 P—Amitriptyline; subst.c. = ? nmol/l NPU01616 P—Clomipramine; subst.c. = ? nmol/l Urine— NPU01858 P—Desipramine; subst.c. = ? nmol/l Barbital; NPU14067 P—Desmethylclomipramine; subst.c. = ? substance concentration nmol/l micromole/liter NPU02472 P—Imipramine; subst.c. = ? nmol/l M = 184,19 g/mol NPU02923 P—Nortriptyline; subst.c. = ? nmol/l NPU04638 U—Barbital; subst.c. = ? µmol/l System(specification)— Antidepressive drug; Plasma— taxon(procedure) Barbital; NPU10277 substance concentration Syst(spec.)—Antidepressive drug; taxon(proc.) = ? nanomole/liter NPU16400 Urine— P—Barbital; subst.c. = ? nmol/l Antidepressive drug; taxon(procedure) Plasma— NPU04585 (total); U—Antidepressive drug; taxon(proc.) = ? arbitrary concentration(procedure) NPU16395 Urine— P—Barbiturate(tot.); arb.c.(proc.) = ? Atenolol; arbitrary concentration(procedure) Urine— M = 266,34 g/mol Barbiturate(total); NPU04579 arbitrary concentration(procedure) U—Atenolol; arb.c.(proc.) = ? Note: F.ex. ; ; ; Barbital; ; ; 5-Ethyl-5- Urine— (4-hydroxyphenyl) barbiturate; ; Atenolol; Pentobarbital; ; ; Talbutal; substance concentration Thiopental micromole/liter NPU08959 M = 266,34 g/mol U—Barbiturate(tot.); arb.c.(proc.) = ? NPU01336 U—Atenolol; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 494 H. OLESEN

Plasma— Urine— Barbiturate(total); ; substance concentration arbitrary concentration(procedure) micromole/liter M = 155,19 g/mol Note: F.ex. Alphenal; Amobarbital; Aprobarbital; NPU04920 Barbital; Butabarbital; Cyclopentobarbital; 5-Ethyl-5- U—Bemegride; arb.c.(proc.) = ? (4-hydroxyphenyl) barbiturate; Pentobarbital; Pentobarbital; Phenobarbital; Secobarbital; Talbutal; Urine— Thiopental Bemegride; NPU01344 substance concentration P—Barbiturate(tot.); subst.c. = ? µmol/l micromole/liter M = 155,19 g/mol Urine— NPU01350 Barbiturate(total); U—Bemegride; subst.c. = ? µmol/l substance concentration micromole/liter Urine— NPU04085 ; U—Barbiturate(tot.); subst.c. = ? µmol/l arbitrary concentration(procedure) M = 421,41 g/mol Urine— NPU01352 Barbiturate; U—Bendroflumethiazide; arb.c.(proc.) = ? arbitrary concentration(list; procedure) NPU04826 Plasma— U—Barbiturate; arb.c.(list; proc.) Bendroflumethiazide; NPU01343 U—Barbital; arb.c.(proc.) = ? substance concentration NPU04769 U—; arb.c.(proc.) = ? micromole/liter NPU03042 U—Pentobarbital; arb.c.(proc.) = ? M = 421,41 g/mol NPU03063 U—Phenobarbital; arb.c.(proc.) = ? NPU08776 NPU08677 U—Thiopental; arb.c.(proc.) = ? P—Bendroflumethiazide; subst.c. = ? µmol/l

Plasma— Urine— Barbiturate; Bendroflumethiazide; substance concentration(list) substance concentration NPU16396 micromole/liter P—Barbiturate; subst.c.(list) M = 421,41 g/mol NPU16400 P—Barbital; subst.c. = ? nmol/l NPU01355 NPU10139 P—Barbital; subst.c. = ? µmol/l U—Bendroflumethiazide; subst.c. = ? µmol/l NPU03954 P—Pentobarbital; subst.c. = ? µmol/l NPU16394 P—Pentobarbital; subst.c. = ? nmol/l Urine— NPU03062 P—Phenobarbital; subst.c. = ? µmol/l Benzbromarone; NPU16390 P—Phenobarbital; subst.c. = ? nmol/l substance concentration mole/liter Plasma— M = 424,11 g/mol Barbiturate; NPU04403 taxon(procedure) U—Benzbromarone; subst.c.= ? prefix ? mol/l Note: F.ex. Alphenal; Amobarbital; Aprobarbital; Barbital; Butabarbital; Cyclopentobarbital; 5-Ethyl-5- Urine— (4-hydroxyphenyl) barbiturate; Pentobarbital; Benzfetamine; Pentobarbital; Phenobarbital; Secobarbital; Talbutal; arbitrary concentration(procedure) Thiopental M = 239,36 g/mol NPU01345 NPU04404 P—Barbiturate; taxon(proc.) = ? U—Benzfetamine; arb.c.(proc.) = ?

Urine— Urine— Barbiturate; Benzfetamine; taxon(procedure) substance concentration NPU04588 micromole/liter U—Barbiturate; taxon(proc.) = ? M = 239,36 g/mol NPU01358 U—Benzfetamine; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 495

Urine— Urine— ; Benzoylecgonine; substance concentration arbitrary concentration(procedure) micromole/liter Note: Cocaine metabolite NPU01360 NPU08994 U—Benzodiazepine; subst.c. = ? µmol/l U—Benzoylecgonine; arb.c.(proc.) = ?

Plasma— Urine— Benzodiazepine; Benzoylecgonine; substance concentration substance concentration nanomole/liter micromole/liter NPU01359 M = 289,33 g/mol P—Benzodiazepine; subst.c. = ? nmol/l Note: Cocaine metabolite NPU08993 Urine— U—Benzoylecgonine; subst.c. = ? µmol/l ; arbitrary concentration(list; procedure) Urine— NPU04827 ; U—Benzodiazepines; arb.c.(list; proc.) arbitrary concentration(procedure) NPU01402 U—; arb.c.(proc.) = ? M = 404,49 g/mol NPU01534 U—; arb.c.(proc.) = ? NPU04338 NPU01880 U—; arb.c.(proc.) = ? U—Benzquinamide; arb.c.(proc.) = ? NPU02062 U—; arb.c.(proc.) = ? NPU02614 U—; arb.c.(proc.) = ? Plasma— NPU02916 U—; arb.c.(proc.) = ? Benzquinamide; NPU02975 U—; arb.c.(proc.) = ? substance concentration mole/liter Urine— M = 404,49 g/mol Benzodiazepines; NPU04340 arbitrary concentration(procedure) P—Benzquinamide; subst.c.= ? prefix ? mol/l NPU08958 U—Benzodiazepines; arb.c.(proc.) = ? Urine— Benzquinamide; Plasma— substance concentration Benzodiazepines; mole/liter taxon(procedure) M = 404,49 g/mol Note: F.ex. Oxazepam; Alprazolam; NPU04339 Benzodiazepine; Bromazepam; Chlordiazepoxide; U—Benzquinamide; subst.c.= ? prefix ? mol/l ; ; ; ; ; N-Desalkylflurazepam; Diazepam; Urine— Flunitrazepam; ; ; Benzthiazide; a-Hydroxyalprazolam substance concentration NPU09010 micromole/liter P—Benzodiazepines; taxon(proc.) = ? M = 431,94 g/mol NPU01363 System(specification)— U—Benzthiazide; subst.c. = ? µmol/l Benzodiazepines; taxon(procedure) Urine— NPU10282 Betaxolol; Syst(spec.)—Benzodiazepines; taxon(proc.) = ? arbitrary concentration(procedure) M = 307,43 g/mol Urine— NPU04405 Benzodiazepines; U—Betaxolol; arb.c.(proc.) = ? taxon(procedure) Note: F.ex. Oxazepam; Alprazolam; Urine— Benzodiazepine; Bromazepam; Chlordiazepoxide; Bevantolol; Clobazam; Clonazepam; Clorazepate; Clotiazepam; arbitrary concentration(procedure) Demoxepam; N-Desalkylflurazepam; Diazepam; M = 345,44 g/mol Flunitrazepam; Flurazepam; Halazepam; NPU04406 a-Hydroxyalprazolam U—Bevantolol; arb.c.(proc.) = ? NPU04062 U—Benzodiazepines; taxon(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 496 H. OLESEN

Urine— Urine— Biopterin; Bromazepam; substance concentration arbitrary concentration(procedure) mole/liter M = 316,16 g/mol M = 237,22 g/mol NPU01402 NPU01373 U—Bromazepam; arb.c.(proc.) = ? U—Biopterin; subst.c.= ? prefix ? mol/l Urine— Urine— Bromazepam; Bisacodyl; substance concentration arbitrary concentration(procedure) micromole/liter M = 361,38 g/mol M = 316,16 g/mol NPU01382 NPU04648 U—Bisacodyl; arb.c.(proc.) = ? U—Bromazepam; subst.c. = ? µmol/l

Urine— Urine— Bisacodyl; ; substance concentration arbitrary concentration(procedure) mole/liter M = 654,62 g/mol M = 361,38 g/mol NPU04341 NPU04779 U—Bromocriptine; arb.c.(proc.) = ? U—Bisacodyl; subst.c.= ? prefix ? mol/l Plasma— Urine— Bromocriptine; Bisoprolol; substance concentration arbitrary concentration(procedure) mole/liter M = 325,45 g/mol M = 654,62 g/mol NPU04407 NPU04343 U—Bisoprolol; arb.c.(proc.) = ? P—Bromocriptine; subst.c.= ? prefix ? mol/l

Urine— Urine— ; Bromocriptine; arbitrary concentration(procedure) substance concentration M = 316,47 g/mol mole/liter NPU04914 M = 654,62 g/mol U—Bolasterone; arb.c.(proc.) = ? NPU04342 U—Bromocriptine; subst.c.= ? prefix ? mol/l Urine— Bolasterone; Urine— substance concentration ; nanomole/liter arbitrary concentration(procedure) M = 316,47 g/mol M = 420,33 g/mol NPU01396 NPU09038 U—Bolasterone; subst.c. = ? nmol/l U—Bromperidol; arb.c.(proc.) = ?

Urine— Plasma— ; Bromperidol; arbitrary concentration(procedure) substance concentration M = 286,40 g/mol mole/liter NPU04921 M = 420,33 g/mol U—Boldenone; arb.c.(proc.) = ? NPU09036 P—Bromperidol; subst.c.= ? prefix ? mol/l Urine— Boldenone; Urine— substance concentration Bromperidol; nanomole/liter substance concentration M = 286,40 g/mol mole/liter NPU01399 M = 420,33 g/mol U—Boldenone; subst.c. = ? nmol/l NPU09037 U—Bromperidol; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 497

Urine— Urine— ; Bunolol; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 393,70 g/mol M = 291,39 g/mol NPU09059 NPU04961 U—Brotizolam; arb.c.(proc.) = ? U—Bunolol; arb.c.(proc.) = ?

Plasma— Urine— Brotizolam; Bunolol; substance concentration substance concentration mole/liter mole/liter M = 393,70 g/mol M = 291,39 g/mol NPU09057 NPU04416 P—Brotizolam; subst.c.= ? prefix ? mol/l U—Bunolol; subst.c.= ? prefix ? mol/l

Urine— Urine— Brotizolam; Bupranolol; substance concentration arbitrary concentration(procedure) mole/liter M = 271,79 g/mol M = 393,70 g/mol NPU04962 NPU09058 U—Bupranolol; arb.c.(proc.) = ? U—Brotizolam; subst.c.= ? prefix ? mol/l Urine— Urine— Bupranolol; ; substance concentration arbitrary concentration(procedure) mole/liter M = 364,42 g/mol M = 271,79 g/mol NPU08604 NPU04419 U—Bumetanide; arb.c.(proc.) = ? U—Bupranolol; subst.c.= ? prefix ? mol/l

Plasma— Urine— Bumetanide; Buprenorphine; substance concentration arbitrary concentration(procedure) mole/liter M = 467,65 g/mol M = 364,42 g/mol NPU04584 NPU01407 U—Buprenorphine; arb.c.(proc.) = ? P—Bumetanide; subst.c.= ? prefix ? mol/l Urine— Urine— Buprenorphine; Bumetanide; substance concentration substance concentration nanomole/liter micromole/liter M = 467,65 g/mol M = 364,42 g/mol NPU01413 NPU01410 U—Buprenorphine; subst.c. = ? nmol/l U—Bumetanide; subst.c. = ? µmol/l Urine— Urine— ; Bunitrolol; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 385,51 g/mol M = 248,32 g/mol NPU04347 NPU04960 U—Buspirone; arb.c.(proc.) = ? U—Bunitrolol; arb.c.(proc.) = ? Urine— Urine— Buspirone; Bunitrolol; substance concentration substance concentration mole/liter mole/liter M = 385,51 g/mol M = 248,32 g/mol NPU04348 NPU04415 U—Buspirone; subst.c.= ? prefix ? mol/l U—Bunitrolol; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 498 H. OLESEN

Plasma— Urine— Buspirone; ; substance concentration substance concentration nanomole/liter micromole/liter M = 385,51 g/mol Other term(s): Hash NPU04349 Note: ; Cannabinol; P—Buspirone; subst.c. = ? nmol/l NPU04622 Urine— U—Cannabinol; subst.c. = ? µmol/l Butalbital; arbitrary concentration(procedure) Urine— M = 224,25 g/mol Cannabinol; Other term(s): Alisobumal; Allylbarbital; Itobarbital; substance concentration Sandoptal nanomole/liter NPU04769 Other term(s): Hash U—Butalbital; arb.c.(proc.) = ? Note: Tetrahydrocannabinols; Cannabinol; Cannabidiol Urine— NPU01452 Butalbital; U—Cannabinol; subst.c. = ? nmol/l substance concentration micromole/liter Urine— M = 224,25 g/mol ; Other term(s): Alisobumal; Allylbarbital; Itobarbital; arbitrary concentration(procedure) Sandoptal M = 340,46 g/mol NPU04770 NPU04922 U—Butalbital; subst.c. = ? µmol/l U—Canrenone; arb.c.(proc.) = ?

Plasma— Urine— ; Canrenone; substance concentration substance concentration micromole/liter micromole/liter M = 194,19 g/mol M = 340,46 g/mol Authority: BAN NPU01455 NPU04420 U—Canrenone; subst.c. = ? µmol/l P—Caffeine; subst.c. = ? µmol/l Plasma— Urine— epoxide; Caffeine; substance concentration substance concentration micromole/liter micromole/liter NPU08964 M = 194,19 g/mol P—Carbamazepine epoxide; subst.c. = ? µmol/l Authority: BAN NPU01434 Patient— U—Caffeine; subst.c. = ? µmol/l Carbamazepine(administered); substance rate() Urine— millimole/day Cannabinol; M = 236,27 g/mol arbitrary concentration(procedure) NPU10025 Other term(s): Hash Pt—Carbamazepine(administered); subst.rate(p.o.) Note: Tetrahydrocannabinols; Cannabinol; = ? mmol/d Cannabidiol NPU08957 Plasma— U—Cannabinol; arb.c.(proc.) = ? Carbamazepine(free); substance concentration micromole/liter M = 236,27 g/mol NPU08974 P—Carbamazepine(free); subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 499

Plasma— Urine— Carbamazepine(total); Carteolol; substance concentration substance concentration micromole/liter mole/liter M = 236,27 g/mol M = 292,38 g/mol NPU01457 NPU04923 P—Carbamazepine(tot.); subst.c. = ? µmol/l U—Carteolol; subst.c.= ? prefix ? mol/l

Urine— Urine— Carbamazepine; Cathartic drug; arbitrary concentration(procedure) arbitrary concentration(list; procedure) M = 236,27 g/mol Other term(s): Laxative NPU04841 NPU08593 U—Carbamazepine; arb.c.(proc.) = ? U—Cathartic drug; arb.c.(list; proc.) NPU01382 U—Bisacodyl; arb.c.(proc.) = ? Urine— NPU03064 U—Phenolphthalein; arb.c.(proc.) = ? Carbamazepine; NPU04820 U—Rhein; arb.c.(proc.) = ? substance concentration micromole/liter Urine— M = 236,27 g/mol ; NPU04842 arbitrary concentration(procedure) U—Carbamazepine; subst.c. = ? µmol/l M = 151,21 g/mol NPU04421 Plasma— U—Cathine; arb.c.(proc.) = ? ; arbitrary concentration(procedure) Urine— M = 394,51 g/mol Cathine; NPU04915 substance concentration P—Carfentanil; arb.c.(proc.) = ? micromole/liter M = 151,21 g/mol Urine— NPU01516 Carfentanil; U—Cathine; subst.c. = ? µmol/l arbitrary concentration(procedure) M = 394,51 g/mol Cerebrospinal fluid— NPU04350 Chloramphenicol; U—Carfentanil; arb.c.(proc.) = ? substance concentration micromole/liter Plasma— NPU12938 Carfentanil; Csf—Chloramphenicol; subst.c. = ? µmol/l substance concentration mole/liter Plasma— M = 394,51 g/mol Chloramphenicol; NPU04352 substance concentration P—Carfentanil; subst.c.= ? prefix ? mol/l micromole/liter NPU12934 Urine— P—Chloramphenicol; subst.c. = ? µmol/l Carfentanil; substance concentration Secretion(specification)— mole/liter Chloramphenicol; M = 394,51 g/mol substance concentration NPU04351 micromole/liter U—Carfentanil; subst.c.= ? prefix ? mol/l NPU12933 Secr(spec.)—Chloramphenicol; subst.c. = ? µmol/l Urine— Carteolol; System(specification)— arbitrary concentration(procedure) Chloramphenicol; M = 292,38 g/mol substance concentration Authority: IFCC/C-LDA; *INN88 micromole/liter NPU14146 NPU17513 U—Carteolol; arb.c.(proc.) = ? Syst(spec.)—Chloramphenicol; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 500 H. OLESEN

Urine— Urine— Chloramphenicol; ; substance concentration substance concentration micromole/liter micromole/liter NPU12937 M = 183,68 g/mol U—Chloramphenicol; subst.c. = ? µmol/l NPU01543 U—Chlorphentermine; subst.c. = ? µmol/l Plasma— Chloraniline; Urine— substance concentration ; micromole/liter arbitrary concentration(procedure) M = 208,98 g/mol M = 318,87 g/mol NPU03854 NPU01544 P—Chloraniline; subst.c. = ? µmol/l U—Chlorpromazine; arb.c.(proc.) = ?

Urine— Urine— Chlordiazepoxide; Chlorpromazine; arbitrary concentration(procedure) substance concentration M = 299,76 g/mol micromole/liter NPU01534 M = 318,87 g/mol U—Chlordiazepoxide; arb.c.(proc.) = ? NPU04781 U—Chlorpromazine; subst.c.= ? µmol/l Urine— Chlordiazepoxide; Plasma— substance concentration Chlorpromazine; micromole/liter substance concentration M = 299,76 g/mol nanomole/liter NPU04550 M = 318,87 g/mol U—Chlordiazepoxide; subst.c. = ? µmol/l NPU04822 P—Chlorpromazine; subst.c.= ? nmol/l Plasma— Chlorhexidine; Urine— substance concentration ; micromole/liter arbitrary concentration(procedure) M = 505,45 g/mol M = 315,87 g/mol NPU03855 NPU01545 P—Chlorhexidine; subst.c. = ? µmol/l U—Chlorprothixene; arb.c.(proc.) = ?

Urine— Urine— Chlorhexidine; Chlorprothixene; substance concentration substance concentration micromole/liter micromole/liter M = 505,45 g/mol M = 315,87 g/mol NPU04422 NPU04783 U—Chlorhexidine; subst.c. = ? µmol/l U—Chlorprothixene; subst.c. = ? µmol/l

Urine— Plasma— ; Chlorprothixene; substance concentration substance concentration micromole/liter nanomole/liter M = 367,20 g/mol M = 315,87 g/mol NPU01540 NPU08777 U—Chlormerodrin; subst.c. = ? µmol/l P—Chlorprothixene; subst.c. = ? nmol/l

Plasma— Urine— Chloroquine; ; substance concentration substance concentration mole/liter micromole/liter M = 319,88 g/mol M = 338,77 g/mol NPU04818 NPU01548 P—Chloroquine; subst.c.= ? prefix ? mol/l U—Chlortalidone; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 501

Urine— Patient— Chlortetracycline; Citalopram(administered); arbitrary substance concentration(procedure) substance rate(oral administration) arbitrary unit/liter micromole/day M = 478,89 g/mol M = 324,40 g/mol NPU08821 NPU10037 U—Chlortetracycline; arb.subst.c.(proc.) = ? Pt—Citalopram(administered); subst.rate(p.o.) = ? arb.unit/l µmol/d

Plasma— Urine— Chlortetracycline; Citalopram; substance concentration arbitrary concentration(procedure) mole/liter M = 324,40 g/mol M = 478,89 g/mol NPU04784 NPU08820 U—Citalopram; arb.c.(proc.) = ? P—Chlortetracycline; subst.c.= ? prefix ? mol/l Urine— Urine— Citalopram; Chlortetracycline; substance concentration substance concentration micromole/liter mole/liter M = 324,40 g/mol M = 478,89 g/mol NPU04785 NPU08822 U—Citalopram; subst.c. = ? µmol/l U—Chlortetracycline; subst.c.= ? prefix ? mol/l Plasma— Blood— Citalopram; Ciclosporin; substance concentration substance concentration nanomole/liter micromole/liter M = 324,40 g/mol M = 1 202,6 g/mol NPU04778 NPU01592 P—Citalopram; subst.c.= ? nmol/l B—Ciclosporin; subst.c. = ? µmol/l Urine— Blood— ; Ciclosporin+metabolite; arbitrary concentration(procedure) substance concentration M = 343,90 g/mol micromole/liter NPU04353 NPU03990 U—Clemastine; arb.c.(proc.) = ? B—Ciclosporin+metabolite; subst.c. = ? µmol/l Plasma— Patient— Clemastine; (administered); substance concentration substance rate(oral administration) mole/liter millimole/day M = 343,90 g/mol M = 252,34 g/mol NPU04355 NPU10036 P—Clemastine; subst.c.= ? prefix ? mol/l Pt—Cimetidine(administered); subst.rate(p.o.) = ? mmol/d Urine— Clemastine; Urine— substance concentration ; mole/liter arbitrary concentration(procedure) M = 343,90 g/mol NPU10296 NPU04354 U—Ciprofloxacin; arb.c.(proc.) = ? U—Clemastine; subst.c.= ? prefix ? mol/l

Urine— ; arbitrary concentration(procedure) M = 277,18 g/mol NPU04963 U—Clenbuterol; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 502 H. OLESEN

Urine— Urine— Clenbuterol; Clobazam; substance concentration substance concentration mole/liter nanomole/liter M = 277,18 g/mol M = 300,74 g/mol NPU04425 NPU04844 U—Clenbuterol; subst.c.= ? prefix ? mol/l U—Clobazam; subst.c. = ? nmol/l

Urine— Urine— ; ; arbitrary substance concentration(procedure) arbitrary concentration(procedure) arbitrary unit/liter M = 259,78 g/mol M = 424,98 g/mol NPU04428 NPU08780 U—Clobenzorex; arb.c.(proc.) = ? U—Clindamycin; arb.subst.c.(proc.) = ? arb.unit/l Urine— Plasma— Clobenzorex; Clindamycin; substance concentration substance concentration micromole/liter mole/liter M = 259,78 g/mol M = 424,98 g/mol NPU01615 NPU08778 U—Clobenzorex; subst.c. = ? µmol/l P—Clindamycin; subst.c.= ? prefix ? mol/l Urine— Urine— ; Clindamycin; arbitrary concentration(procedure) substance concentration M = 161,66 g/mol mole/liter NPU09063 M = 424,98 g/mol U—Clomethiazole; arb.c.(proc.) = ? NPU08779 U—Clindamycin; subst.c.= ? prefix ? mol/l Plasma— Clomethiazole; Patient— substance concentration Clobazam(administered); mole/liter substance rate(oral administration) M = 161,66 g/mol micromole/day NPU09061 M = 300,74 g/mol P—Clomethiazole; subst.c.= ? prefix ? mol/l NPU10038 Pt—Clobazam(administered); subst.rate(p.o.) = ? Urine— µmol/d Clomethiazole; substance concentration Urine— mole/liter Clobazam; M = 161,66 g/mol arbitrary concentration(procedure) NPU09062 M = 300,74 g/mol U—Clomethiazole; subst.c.= ? prefix ? mol/l NPU04843 U—Clobazam; arb.c.(proc.) = ? Patient— Clomipramine(administered); Plasma— substance rate(oral administration) Clobazam; micromole/day substance concentration M = 314,87 g/mol nanomole/liter NPU10039 M = 300,74 g/mol Pt—Clomipramine(administered); subst.rate(p.o.) = NPU03932 ? µmol/d P—Clobazam; subst.c. = ? nmol/l Urine— Clomipramine; arbitrary concentration(procedure) M = 314,87 g/mol NPU01617 U—Clomipramine; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 503

Plasma— Urine— Clomipramine; ; substance concentration substance concentration nanomole/liter mole/liter M = 314,87 g/mol M = 345,86 g/mol NPU01616 NPU04431 P—Clomipramine; subst.c. = ? nmol/l U—Clopamide; subst.c.= ? prefix ? mol/l

Urine— Urine— Clomipramine; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 401,0 g/mol M = 314,87 g/mol NPU04088 NPU04787 U—Clopenthixol; arb.c.(proc.) = ? U—Clomipramine; subst.c. = ? nmol/l Urine— Plasma— Clopenthixol; Clomipramine+Desmethylclomipramine; substance concentration substance concentration mole/liter nanomole/liter M = 401,0 g/mol Note: M (clomipramine) = 314,87 g/mol NPU04087 NPU03933 U—Clopenthixol; subst.c.= ? prefix ? mol/l P—Clomipramine+Desmethylclomipramine; subst.c. = ? nmol/l Plasma— Clopenthixol; Patient— substance concentration Clonazepam(administered); nanomole/liter substance rate(oral administration) M = 401,0 g/mol micromole/day NPU04086 M = 315,72 g/mol P—Clopenthixol; subst.c. = ? nmol/l NPU10040 Pt—Clonazepam(administered); subst.rate(p.o.) = ? Urine— µmol/d Clorazepate; arbitrary concentration(procedure) Urine— Note: M (anion) = 313,73 g/mol Clonazepam; NPU01911 arbitrary concentration(procedure) U—Clorazepate; arb.c.(proc.) = ? M = 315,72 g/mol NPU04847 Urine— U—Clonazepam; arb.c.(proc.) = ? Clorazepate; substance concentration Plasma— micromole/liter Clonazepam; Note: M (anion) = 313,73 g/mol substance concentration NPU04849 nanomole/liter U—Clorazepate; subst.c. = ? µmol/l M = 315,72 g/mol NPU01618 Urine— P—Clonazepam; subst.c. = ? nmol/l Clorprenaline; arbitrary concentration(procedure) Urine— M = 213,71 g/mol Clonazepam; NPU04434 substance concentration U—Clorprenaline; arb.c.(proc.) = ? nanomole/liter M = 315,72 g/mol Urine— NPU04848 Clorprenaline; U—Clonazepam; subst.c. = ? nmol/l substance concentration micromole/liter M = 213,71 g/mol NPU01622 U—Clorprenaline; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 504 H. OLESEN

Urine— Urine— ; Codeine; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 322,87 g/mol M = 299,37 g/mol NPU04437 Authority: BAN U—Clostebol; arb.c.(proc.) = ? NPU01710 U—Codeine; arb.c.(proc.) = ? Urine— Clostebol; Urine— substance concentration Codeine; micromole/liter substance concentration M = 322,87 g/mol micromole/liter NPU01625 M = 299,37 g/mol U—Clostebol; subst.c. = ? µmol/l Authority: BAN NPU01713 Urine— U—Codeine; subst.c. = ? µmol/l ; arbitrary concentration(procedure) Plasma— M = 326,83 g/mol Codeine; NPU09039 substance concentration U—Clozapine; arb.c.(proc.)= ? nanomole/liter M = 299,37 g/mol Plasma— Authority: BAN Clozapine; NPU08781 substance concentration P—Codeine; subst.c. = ? nmol/l nanomole/liter M = 326,83 g/mol Urine— NPU04114 Colchicine; P—Clozapine; subst.c. = ? nmol/l arbitrary concentration(procedure) M = 399,44 g/mol Urine— NPU04356 Clozapine; U—Colchicine; arb.c.(proc.) = ? substance concentration nanomole/liter Plasma— M = 326,83 g/mol Colchicine; NPU04116 substance concentration U—Clozapine; subst.c. = ? nmol/l mole/liter M = 399,44 g/mol Urine— NPU04358 Cocaine; P—Colchicine; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) M = 303,36 g/mol Urine— Authority: BAN Colchicine; NPU01706 substance concentration U—Cocaine; arb.c.(proc.) = ? mole/liter M = 399,44 g/mol Urine— NPU04357 Cocaine+metabolite; U—Colchicine; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) Note: Cocaine; Benzoylecgonine; Ecgonine; Plasma— Ecgonine methylester ; NPU08955 substance concentration U—Cocaine+metabolite; arb.c.(proc.) = ? nanomole/liter M = 176,21 g/mol Urine— NPU10041 Cocaine+metabolite; P—Cotinine; subst.c. = ? nmol/l substance concentration micromole/liter Note: Cocaine; Benzoylecgonine; Ecgonine; Ecgonine methylester NPU01709 U—Cocaine+metabolite; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 505

Urine— Urine— Cotinine; Dantrolene; substance concentration substance concentration nanomole/liter mole/liter M = 176,21 g/mol M = 314,26 g/mol NPU10042 NPU04365 U—Cotinine; subst.c. = ? nmol/l U—Dantrolene; subst.c.= ? prefix ? mol/l

Urine— Urine— Cropropamide; Dantron; arbitrary concentration(procedure) substance concentration M = 240,35 g/mol mole/liter NPU04440 M = 240,21 g/mol U—Cropropamide; arb.c.(proc.) = ? NPU01848 U—Dantron; subst.c.= ? prefix ? mol/l Urine— Cropropamide; Urine— substance concentration Debrisoquine; micromole/liter arbitrary substance concentration(procedure) M = 240,35 g/mol arbitrary unit/liter NPU01812 M = 175,23 g/mol U—Cropropamide; subst.c. = ? µmol/l NPU08783 U—Debrisoquine; arb.subst.c.(proc.) = ? arb.unit/l Urine— Crotetamide; Urine— arbitrary concentration(procedure) Debrisoquine; M = 226,32 g/mol substance concentration NPU04443 mole/liter U—Crotetamide; arb.c.(proc.) = ? M = 175,23 g/mol NPU08782 Urine— U—Debrisoquine; subst.c.= ? prefix ? mol/l Crotetamide; substance concentration Plasma— micromole/liter Deferoxamine(Fe); M = 226,32 g/mol substance concentration Other term(s): Crotethamide micromole/liter NPU01815 M = 560,71 g/mol U—Crotetamide; subst.c. = ? µmol/l NPU10137 P—Deferoxamine(Fe); subst.c. = ? µmol/l Urine— ; Plasma— substance concentration Desethylamiodarone; mole/liter substance concentration M = 337,47 g/mol micromole/liter NPU04446 M = 617,27 g/mol U—Danazol; subst.c.= ? prefix ? mol/l NPU08618 P—Desethylamiodarone; subst.c. = ? µmol/l Urine— Dantrolene; Urine— arbitrary concentration(procedure) Desipramine; M = 314,26 g/mol arbitrary concentration(procedure) NPU04364 M = 266,37 g/mol U—Dantrolene; arb.c.(proc.) = ? NPU01859 U—Desipramine; arb.c.(proc.) = ? Plasma— Dantrolene; Plasma— substance concentration Desipramine; mole/liter substance concentration M = 314,26 g/mol nanomole/liter NPU04366 M = 266,37 g/mol P—Dantrolene; subst.c.= ? prefix ? mol/l NPU01858 P—Desipramine; subst.c. = ? nmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 506 H. OLESEN

Urine— Plasma— Desipramine; Dextropropoxyphene; substance concentration arbitrary concentration(procedure) nanomole/liter M = 339,48 g/mol M = 266,37 g/mol Other term(s): Propoxyphene NPU04789 NPU04917 U—Desipramine; subst.c. = ? nmol/l P—Dextropropoxyphene; arb.c.(proc.) = ?

Plasma— System(specification)— Desmethylclomipramine; Dextropropoxyphene; substance concentration arbitrary concentration(procedure) nanomole/liter M = 339,48 g/mol Note: M (clomipramine) = 314,87 g/mol Other term(s): Propoxyphene NPU14067 NPU10305 P—Desmethylclomipramine; subst.c. = ? nmol/l Syst(spec.)—Dextropropoxyphene; arb.c.(proc.) = ?

Plasma— Urine— Desmethyldoxepin; Dextropropoxyphene; substance concentration arbitrary concentration(procedure) nanomole/liter M = 339,48 g/mol NPU10304 Other term(s): Propoxyphene P—Desmethyldoxepin; subst.c. = ? nmol/l NPU01866 U—Dextropropoxyphene; arb.c.(proc.) = ? Urine— ; Plasma— arbitrary concentration(procedure) Dextropropoxyphene; M = 271,41 g/mol substance concentration NPU04580 micromole/liter U—Dextromethorphan; arb.c.(proc.) = ? M = 339,48 g/mol Other term(s): Propoxyphene Plasma— NPU01863 Dextromethorphan; P—Dextropropoxyphene; subst.c. = ? µmol/l substance concentration mole/liter Urine— M = 271,41 g/mol Dextropropoxyphene; NPU04370 substance concentration P—Dextromethorphan; subst.c.= ? prefix ? mol/l micromole/liter M = 339,48 g/mol Urine— Other term(s): Propoxyphene Dextromethorphan; NPU01867 substance concentration U—Dextropropoxyphene; subst.c. = ? µmol/l mole/liter M = 271,41 g/mol Patient(Urine)— NPU04581 Dextropropoxyphene; U—Dextromethorphan; subst.c.= ? prefix ? mol/l substance rate micromole/day Urine— M = 339,48 g/mol Dextromoramide; NPU10138 arbitrary concentration(procedure) Pt(U)—Dextropropoxyphene; subst.rate = ? µmol/d M = 392,54 g/mol NPU04916 Urine— U—Dextromoramide; arb.c.(proc.) = ? Diamorphine; arbitrary concentration(procedure) Urine— M = 369,42 g/mol Dextromoramide; Other term(s): substance concentration Authority: BAN micromole/liter NPU04450 M = 392,54 g/mol U—Diamorphine; arb.c.(proc.) = ? NPU01862 U—Dextromoramide; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 507

Urine— Urine— Diamorphine; Diclophenamide; substance concentration arbitrary concentration(procedure) micromole/liter M = 305,16 g/mol M = 369,42 g/mol NPU04451 Other term(s): Heroin U—Diclophenamide; arb.c.(proc.) = ? Authority: BAN NPU01878 Urine— U—Diamorphine; subst.c. = ? µmol/l Diclophenamide; substance concentration Urine— micromole/liter Diazepam; M = 305,16 g/mol arbitrary concentration(procedure) Other term(s): Dichlorphenamide M = 284,74 g/mol NPU01885 NPU01880 U—Diclophenamide; subst.c. = ? µmol/l U—Diazepam; arb.c.(proc.) = ? Plasma— Plasma— ; Diazepam; substance concentration substance concentration mole/liter micromole/liter M = 470,33 g/mol M = 284,74 g/mol NPU08784 NPU01879 P—Dicloxacillin; subst.c.= ? prefix ? mol/l P—Diazepam; subst.c. = ? µmol/l Plasma— Urine— ; Diazepam; substance concentration substance concentration nanomole/liter micromole/liter M = 764,92 g/mol M = 284,74 g/mol NPU04786 NPU04665 P—Digitoxin; subst.c.= ? nmol/l U—Diazepam; subst.c. = ? µmol/l Plasma— Urine— Digoxin; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 296,16 g/mol M = 780,92 g/mol NPU04371 NPU01886 U—Diclofenac; arb.c.(proc.) = ? P—Digoxin; subst.c. = ? nmol/l

Plasma— Urine— Diclofenac; ; substance concentration arbitrary concentration(procedure) mole/liter M = 301,37 g/mol M = 296,16 g/mol NPU04452 NPU04373 U—Dihydrocodeine; arb.c.(proc.) = ? P—Diclofenac; subst.c.= ? prefix ? mol/l Urine— Urine— Dihydrocodeine; Diclofenac; substance concentration substance concentration micromole/liter mole/liter M = 301,37 g/mol M = 296,16 g/mol NPU01889 NPU04372 U—Dihydrocodeine; subst.c. = ? µmol/l U—Diclofenac; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 508 H. OLESEN

Urine— Urine— ; Dimethyltryptamine; arbitrary concentration(procedure) substance concentration M = 414,52 g/mol micromole/liter NPU04374 M = 188,27 g/mol U—Diltiazem; arb.c.(proc.) = ? NPU01904 U—Dimethyltryptamine; subst.c. = ? µmol/l Plasma— Diltiazem; Urine— substance concentration ; mole/liter arbitrary concentration(procedure) M = 414,52 g/mol M = 255,35 g/mol NPU04376 NPU01906 P—Diltiazem; subst.c.= ? prefix ? mol/l U—Diphenhydramine; arb.c.(proc.) = ?

Urine— Urine— Diltiazem; Diphenhydramine; substance concentration substance concentration mole/liter micromole/liter M = 414,52 g/mol M = 255,35 g/mol NPU04375 NPU04791 U—Diltiazem; subst.c.= ? prefix ? mol/l U—Diphenhydramine; subst.c. = ? µmol/l

Urine— Urine— Dimetamfetamine; Diphenoxylic acid; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 163,26 g/mol M = 452,57 g/mol Other term(s): Dimethylamfetamine NPU04670 NPU04453 U—Diphenoxylic acid; arb.c.(proc.) = ? U—Dimetamfetamine; arb.c.(proc.) = ? Plasma— Urine— Diphenoxylic acid; Dimetamfetamine; substance concentration substance concentration mole/liter micromole/liter M = 452,57 g/mol M = 163,26 g/mol NPU04377 Other term(s): Dimethylamfetamine P—Diphenoxylic acid; subst.c.= ? prefix ? mol/l NPU01902 U—Dimetamfetamine; subst.c. = ? µmol/l Urine— Diphenoxylic acid; Plasma— substance concentration Dimethadione; mole/liter substance concentration M = 452,57 g/mol millimole/liter NPU04458 M = 129,11 g/mol U—Diphenoxylic acid; subst.c.= ? prefix ? mol/l NPU10140 P—Dimethadione; subst.c. = ? mmol/l Urine— Dipipanone; Plasma— arbitrary concentration(procedure) Dimethyltryptamine; M = 349,52 g/mol substance concentration NPU04454 micromole/liter U—Dipipanone; arb.c.(proc.) = ? M = 188,27 g/mol NPU01903 Urine— P—Dimethyltryptamine; subst.c. = ? µmol/l Dipipanone; substance concentration micromole/liter M = 349,52 g/mol NPU01910 U—Dipipanone; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 509

Plasma— Urine— Disopyramide; Dosulepin; substance concentration substance concentration micromole/liter micromole/liter M = 339,47 g/mol M = 295,45 g/mol NPU01912 Other term(s): Dothiepin P—Disopyramide; subst.c. = ? µmol/l NPU04794 U—Dosulepin; subst.c. = ? µmol/l Urine— drug; Plasma— arbitrary concentration(list; procedure) Dosulepin+; NPU04792 substance concentration U—Diuretic drug; arb.c.(list; proc.) micromole/liter NPU01352 U—Bendroflumethiazide; arb.c. Other term(s): Dothiepin for Dosulepin (proc.) = ? NPU10321 NPU08604 U—Bumetanide; arb.c.(proc.) = ? P—Dosulepin+Northiaden; subst.c. = ? µmol/l NPU02138 U—; arb.c.(proc.) = ? NPU04597 U—; arb.c.(proc.) = ? Plasma— ; Urine— substance concentration Diuretic drug; mole/liter taxon(procedure) M = 451,48 g/mol NPU04578 NPU08786 U—Diuretic drug; taxon(proc.) = ? P—Doxazosin; subst.c.= ? prefix ? mol/l

Urine— Urine— ; Doxepin; substance concentration arbitrary concentration(procedure) nanomole/liter M = 279,38 g/mol M = 153,18 g/mol NPU01925 NPU14174 U—Doxepin; arb.c.(proc.) = ? U—Dopamine; subst.c. = ? nmol/l Plasma— Patient(Urine)— Doxepin; Dopamine; substance concentration substance rate nanomole/liter nanomole/day M = 279,38 g/mol M = 153,18 g/mol NPU01924 NPU14175 P—Doxepin; subst.c. = ? nmol/l Pt(U)—Dopamine; subst.rate = ? nmol/d Urine— Urine— Doxepin; Dosulepin; substance concentration arbitrary concentration(procedure) nanomole/liter M = 295,45 g/mol M = 279,38 g/mol Other term(s): Dothiepin NPU04796 NPU04793 U—Doxepin; subst.c. = ? nmol/l U—Dosulepin; arb.c.(proc.) = ? Plasma— Plasma— Doxepin+Desmethyldoxepin; Dosulepin; substance concentration substance concentration nanomole/liter micromole/liter Note: M (doxepin) = 279,38 g/mol M = 295,45 g/mol NPU03934 Other term(s): Dothiepin P—Doxepin+Desmethyldoxepin; subst.c. = ? nmol/l NPU08785 P—Dosulepin; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 510 H. OLESEN

Plasma— Urine— Doxycycline; ; substance concentration substance concentration mole/liter mole/liter M = 462,46 g/mol M = 304,46 g/mol NPU08787 NPU04456 P—Doxycycline; subst.c.= ? prefix ? mol/l U—Drostanolone; subst.c.= ? prefix ? mol/l

Urine— Urine— ; Enalapril; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 270,38 g/mol M = 376,45 g/mol NPU04378 NPU04381 U—Doxylamine; arb.c.(proc.) = ? U—Enalapril; arb.c.(proc.) = ?

Plasma— Plasma— Doxylamine; Enalapril; substance concentration substance concentration mole/liter mole/liter M = 270,38 g/mol M = 376,45 g/mol NPU04380 NPU04383 P—Doxylamine; subst.c.= ? prefix ? mol/l P—Enalapril; subst.c.= ? prefix ? mol/l

Urine— Urine— Doxylamine; Enalapril; substance concentration substance concentration mole/liter mole/liter M = 270,38 g/mol M = 376,45 g/mol NPU04379 NPU04382 U—Doxylamine; subst.c.= ? prefix ? mol/l U—Enalapril; subst.c.= ? prefix ? mol/l

Urine— Plasma— ; Endothelin; arbitrary concentration(procedure) substance concentration M = 379,44 g/mol picomole/liter NPU09042 Other term(s): Endothelin-1; ET-1 U—Droperidol; arb.c.(proc.) = ? Note: M: approx. 2 500 NPU10141 Plasma— P—Endothelin; subst.c. = ? pmol/l Droperidol; substance concentration Plasma— mole/liter Enrofloxacin; M = 379,44 g/mol substance concentration NPU09040 mole/liter P—Droperidol; subst.c.= ? prefix ? mol/l M = 359,40 g/mol NPU08788 Urine— P—Enrofloxacin; subst.c.= ? prefix ? mol/l Droperidol; substance concentration Urine— mole/liter Ephedrine; M = 379,44 g/mol arbitrary concentration(procedure) NPU09041 M = 165,23 g/mol U—Droperidol; subst.c.= ? prefix ? mol/l Authority: BAN NPU04457 Urine— U—Ephedrine; arb.c.(proc.) = ? Drostanolone; arbitrary concentration(procedure) M = 304,46 g/mol NPU04455 U—Drostanolone; arb.c.(proc.) = ?

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Urine— Urine— Ephedrine; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 223,27 g/mol M = 165,23 g/mol NPU04462 Authority: BAN U—Etamivan; arb.c.(proc.) = ? NPU01938 U—Ephedrine; subst.c. = ? µmol/l Urine— Etamivan; Plasma— substance concentration ; micromole/liter substance concentration M = 223,27 g/mol mole/liter NPU01991 NPU14351 U—Etamivan; subst.c. = ? µmol/l P—Erythromycin; subst.c.= ? prefix ? mol/l Urine— Urine— Ethambutol; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 204,31 g/mol M = 294,74 g/mol NPU04384 NPU01971 U—Ethambutol; arb.c.(proc.) = ? U—Estazolam; arb.c.(proc.) = ? Plasma— Urine— Ethambutol; Estazolam; substance concentration substance concentration micromole/liter micromole/liter M = 204,31 g/mol M = 294,74 g/mol NPU04386 NPU01686 P—Ethambutol; subst.c.= ? µmol/l U—Estazolam; subst.c. = ? µmol/l Urine— Plasma— Ethambutol; Estazolam; substance concentration substance concentration micromole/liter nanomole/liter M = 204,31 g/mol M = 294,74 g/mol NPU04385 NPU09060 U—Ethambutol; subst.c. = ? µmol/l P—Estazolam; subst.c. = ? nmol/l Urine— Urine— Ethanol; Etacrynate; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 46,07 g/mol Note: M (anion) = 302,14 g/mol NPU04592 NPU04461 U—Ethanol; arb.c.(proc.) = ? U—Etacrynate; arb.c.(proc.) = ? Plasma— Urine— Ethanol; Etacrynate; substance concentration substance concentration millimole/liter micromole/liter M = 46,07 g/mol Note: M (anion) = 302,14 g/mol Other term(s): ; Ethyl alcohol NPU01985 NPU01992 U—Etacrynate; subst.c. = ? µmol/l P—Ethanol; subst.c. = ? mmol/l

Urine— Urine— ; Ethanol; substance concentration substance concentration micromole/liter millimole/liter M = 193,28 g/mol M = 46,07 g/mol NPU01988 Other term(s): Alcohol; Ethyl alcohol U—Etafedrine; subst.c. = ? µmol/l NPU01993 U—Ethanol; subst.c. = ? mmol/l

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Plasma— Urine— Ethanolamine; Ethylmorphine; substance concentration substance concentration micromole/liter micromole/liter M = 61,08 g/mol M = 313,38 g/mol NPU01994 Authority: BAN P—Ethanolamine; subst.c. = ? µmol/l NPU02003 U—Ethylmorphine; subst.c. = ? µmol/l Urine— Ethanolamine; Urine— substance concentration N- micromole/liter Ethylnicotinamide; M = 61,08 g/mol substance concentration NPU01995 mole/liter U—Ethanolamine; subst.c. = ? µmol/l M = 150,18 g/mol NPU02004 Urine— U—N-Ethylnicotinamide; subst.c.= ? prefix ? mol/l Ethoheptazine; arbitrary concentration(procedure) Urine— M = 261,35 g/mol Etidocaine; NPU04463 arbitrary concentration(procedure) U—Ethoheptazine; arb.c.(proc.) = ? M = 276,42 g/mol NPU04387 Urine— U—Etidocaine; arb.c.(proc.) = ? Ethoheptazine; substance concentration Plasma— micromole/liter Etidocaine; M = 261,35 g/mol substance concentration NPU01998 mole/liter U—Ethoheptazine; subst.c. = ? µmol/l M = 276,42 g/mol NPU04389 Plasma— P—Etidocaine; subst.c.= ? prefix ? mol/l Ethosuximide; substance concentration Urine— micromole/liter Etidocaine; M = 141,17 g/mol substance concentration NPU01999 mole/liter P—Ethosuximide; subst.c. = ? µmol/l M = 276,42 g/mol NPU04388 Plasma— U—Etidocaine; subst.c.= ? prefix ? mol/l Ethotoin; substance concentration Urine— micromole/liter ; M = 204,22 g/mol arbitrary concentration(procedure) NPU10147 M = 163,26 g/mol P—Ethotoin; subst.c. = ? µmol/l Other term(s): Ethylamfetamine NPU04467 Plasma— U—Etilamfetamine; arb.c.(proc.) = ? Ethylenediamine; substance concentration Urine— mole/liter Etilamfetamine; M = 60,10 g/mol substance concentration NPU08789 micromole/liter P—Ethylenediamine; subst.c.= ? prefix ? mol/l M = 163,25 g/mol Other term(s): Ethylamfetamine Urine— NPU02007 Ethylmorphine; U—Etilamfetamine; subst.c. = ? µmol/l arbitrary concentration(procedure) M = 313,38 g/mol Authority: BAN NPU04464 U—Ethylmorphine; arb.c.(proc.) = ?

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Urine— Urine— ; ; arbitrary concentration(procedure) substance concentration M = 181,23 g/mol micromole/liter NPU04471 M = 215,34 g/mol U—Etilefrine; arb.c.(proc.) = ? NPU02024 U—Fencamfamin; subst.c. = ? µmol/l Urine— Etilefrine; Urine— substance concentration Fenetylline; micromole/liter arbitrary concentration(procedure) M = 181,23 g/mol M = 341,40 g/mol NPU02010 NPU04474 U—Etilefrine; subst.c. = ? µmol/l U—Fenetylline; arb.c.(proc.) = ?

Urine— Urine— ; Fenetylline; arbitrary concentration(procedure) substance concentration M = 337,45 g/mol micromole/liter NPU04390 M = 341,41 g/mol U—Famotidine; arb.c.(proc.) = ? NPU02027 U—Fenetylline; subst.c. = ? µmol/l Plasma— Famotidine; Urine— substance concentration Fenfluramine; mole/liter arbitrary concentration(procedure) M = 337,45 g/mol M = 231,27 g/mol NPU04392 NPU02028 P—Famotidine; subst.c.= ? prefix ? mol/l U—Fenfluramine; arb.c.(proc.) = ?

Urine— Urine— Famotidine; Fenfluramine; substance concentration substance concentration mole/liter micromole/liter M = 337,45 g/mol M = 231,27 g/mol NPU04391 NPU04475 U—Famotidine; subst.c.= ? prefix ? mol/l U—Fenfluramine; subst.c. = ? µmol/l

Patient— Urine— (administered); ; substance rate(oral administration) substance concentration millimole/day micromole/liter NPU10149 M = 303,37 g/mol Pt—Felbamate(administered); subst.rate(p.o.) = ? NPU04476 mmol/d U—Fenoterol; subst.c. = ? µmol/l

Plasma— Urine— Felbamate; ; substance concentration substance concentration micromole/liter micromole/liter M = 238,24 g/mol M = 188,27 g/mol NPU10148 NPU02031 P—Felbamate; subst.c. = ? µmol/l U—Fenproporex; subst.c. = ? µmol/l

Urine— Plasma— Fencamfamin; Fentanyl; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 215,34 g/mol M = 336,46 g/mol NPU04472 NPU04485 U—Fencamfamin; arb.c.(proc.) = ? P—Fentanyl; arb.c.(proc.) = ?

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Urine— System(specification)— Fentanyl; Flucytosine; arbitrary concentration(procedure) substance concentration M = 336,46 g/mol micromole/liter NPU02032 NPU17518 U—Fentanyl; arb.c.(proc.) = ? Syst(spec.)—Flucytosine; subst.c. = ? µmol/l

Plasma— Urine— Fentanyl; Flucytosine; substance concentration substance concentration nanomole/liter micromole/liter M = 336,46 g/mol NPU12948 NPU08918 U—Flucytosine; subst.c. = ? µmol/l P—Fentanyl; subst.c. = ? nmol/l Plasma— Urine— ; Fentanyl; substance concentration substance concentration micromole/liter nanomole/liter M = 303,29 g/mol M = 336,46 g/mol NPU10151 NPU04686 P—Flumazenil; subst.c. = ? µmol/l U—Fentanyl; subst.c. = ? nmol/l Urine— Plasma— Flunitrazepam; ; arbitrary concentration(procedure) substance concentration M = 313,29 g/mol micromole/liter NPU02062 M = 414,35 g/mol U—Flunitrazepam; arb.c.(proc.) = ? NPU02059 P—Flecainide; subst.c. = ? µmol/l Urine— Flunitrazepam; Plasma— substance concentration Flucytosine; micromole/liter substance concentration M = 313,29 g/mol mole/liter NPU04685 M = 129,09 g/mol U—Flunitrazepam; subst.c. = ? µmol/l NPU04788 P—Flucytosine; subst.c.= ? prefix ? mol/l Plasma— Flunitrazepam; Cerebrospinal fluid— substance concentration Flucytosine; nanomole/liter substance concentration M = 313,29 g/mol micromole/liter NPU04795 NPU12950 P—Flunitrazepam; subst.c.= ? nmol/l Csf—Flucytosine; subst.c. = ? µmol/l Patient— Plasma— (administered); Flucytosine; substance rate(oral administration) substance concentration micromole/day micromole/liter M = 309,33 g/mol NPU12947 NPU10257 P—Flucytosine; subst.c. = ? µmol/l Pt—Fluoxetine(administered); subst.rate(p.o.) = ? µmol/d Secretion(specification)— Flucytosine; Urine— substance concentration Fluoxetine; micromole/liter arbitrary concentration(procedure) NPU12949 M = 309,33 g/mol Secr(spec.)—Flucytosine; subst.c. = ? µmol/l NPU09072 U—Fluoxetine; arb.c.(proc.) = ?

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Plasma— Urine— Fluoxetine; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 437,53 g/mol M = 309,33 g/mol NPU02068 NPU08790 U—Fluphenazine; arb.c.(proc.) = ? P—Fluoxetine; subst.c. = ? nmol/l Plasma— Urine— Fluphenazine; Fluoxetine; substance concentration substance concentration nanomole/liter nanomole/liter M = 437,53 g/mol M = 309,33 g/mol NPU04790 NPU09071 P—Fluphenazine; subst.c.= ? nmol/l U—Fluoxetine; subst.c. = ? nmol/l Urine— Urine— Fluphenazine; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 336,45 g/mol M = 437,53 g/mol NPU04687 NPU09035 U—Fluoxymesterone; arb.c.(proc.) = ? U—Fluphenazine; subst.c.= ? nmol/l

Plasma— Urine— Fluoxymesterone; Flurazepam; substance concentration arbitrary concentration(procedure) nanomole/liter M = 387,89 g/mol M = 336,45 g/mol NPU02069 NPU04393 U—Flurazepam; arb.c.(proc.) = ? P—Fluoxymesterone; subst.c.= ? nmol/l Urine— Urine— Flurazepam; Fluoxymesterone; substance concentration substance concentration micromole/liter nanomole/liter M = 387,89 g/mol M = 336,45 g/mol NPU01587 NPU02066 U—Flurazepam; subst.c. = ? µmol/l U—Fluoxymesterone; subst.c. = ? nmol/l Patient— Urine— (administered); ; substance rate(oral administration) arbitrary concentration(procedure) micromole/day M = 434,54 g/mol M = 318,34 g/mol NPU02067 NPU10310 U—Flupentixol; arb.c.(proc.) = ? Pt—Fluvoxamine(administered); subst.rate(p.o.) = ? µmol/d Plasma— Flupentixol; Urine— substance concentration Fluvoxamine; nanomole/liter arbitrary concentration(procedure) M = 434,54 g/mol M = 318,34 g/mol NPU04797 NPU09073 P—Flupentixol; subst.c.= ? nmol/l U—Fluvoxamine; arb.c.(proc.)= ?

Urine— Plasma— Flupentixol; Fluvoxamine; substance concentration substance concentration nanomole/liter nanomole/liter M = 434,54 g/mol M = 318,34 g/mol NPU03740 NPU04117 U—Flupentixol; subst.c.= ? nmol/l P—Fluvoxamine; subst.c. = ? nmol/l

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Urine— Plasma— Fluvoxamine; Furosemide; substance concentration substance concentration nanomole/liter micromole/liter M = 318,34 g/mol M = 330,75 g/mol NPU04118 NPU08791 U—Fluvoxamine; subst.c.= ? nmol/l P—Furosemide; subst.c. = ? µmol/l

Urine— Urine— ; Furosemide; arbitrary concentration(procedure) substance concentration M = 344,45 g/mol micromole/liter NPU04489 M = 330,75 g/mol U—Formebolone; arb.c.(proc.) = ? NPU02141 U—Furosemide; subst.c. = ? µmol/l Urine— Formebolone; Plasma— substance concentration ; mole/liter substance concentration M = 344,45 g/mol micromole/liter NPU04935 M = 171,24 g/mol U—Formebolone; subst.c.= ? prefix ? mol/l NPU10155 P—Gabapentin; subst.c. = ? µmol/l Urine— Fucidin; Patient— arbitrary substance concentration(procedure) (administered); arbitrary unit/liter substance rate(oral administration) NPU10154 micromole/day U—Fucidin; arb.subst.c.(proc.) = ? arb.unit/l M = 250,35 g/mol NPU10246 Plasma— Pt—Gemfibrozil(administered); subst.rate(p.o.) = ? Fucidin; µmol/d substance concentration mole/liter Plasma— NPU10311 Gentamicin; P—Fucidin; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) Note: M: mean 463,57 Urine— NPU12400 ; P—Gentamicin; arb.c.(proc.) = ? arbitrary concentration(procedure) M = 229,31 g/mol Urine— NPU04490 Gentamicin; U—Furfenorex; arb.c.(proc.) = ? arbitrary concentration(procedure) Note: M: mean 463,57 Urine— NPU10241 Furfenorex; U—Gentamicin; arb.c.(proc.) = ? substance concentration micromole/liter Cerebrospinal fluid— M = 229,31 g/mol Gentamicin; NPU02137 substance concentration U—Furfenorex; subst.c. = ? µmol/l micromole/liter Note: M: mean 463,57 Urine— NPU17433 Furosemide; Csf—Gentamicin; subst.c. = ? µmol/l arbitrary concentration(procedure) M = 330,75 g/mol Plasma— NPU02138 Gentamicin; U—Furosemide; arb.c.(proc.) = ? substance concentration micromole/liter Note: M:mean 463,57 NPU02164 P—Gentamicin; subst.c. = ? µmol/l

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Secretion(specification)— Urine— Gentamicin; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 375,88 g/mol Note: M: mean 463,57 NPU02316 NPU12921 U—Haloperidol; arb.c.(proc.) = ? Secr(spec.)—Gentamicin; subst.c. = ? µmol/l Plasma— Urine— Haloperidol; Gentamicin; substance concentration substance concentration nanomole/liter micromole/liter M = 375,88 g/mol Note: M: mean 463,57 NPU03937 NPU12920 P—Haloperidol; subst.c. = ? nmol/l U—Gentamicin; subst.c. = ? µmol/l Urine— Plasma— Haloperidol; ; substance concentration substance concentration nanomole/liter mole/liter M = 375,88 g/mol M = 494,01 g/mol NPU04582 NPU04799 U—Haloperidol; subst.c. = ? nmol/l P—Glibenclamide; subst.c.= ? prefix ? mol/l Urine— Urine— ; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 145,24 g/mol M = 217,26 g/mol NPU04493 NPU02270 U—Heptaminol; arb.c.(proc.) = ? U—Glutethimide; arb.c.(proc.) = ? Urine— Urine— Heptaminol; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 352,77 g/mol M = 145,24 g/mol NPU04394 NPU02353 U—Griseofulvin; arb.c.(proc.) = ? U—Heptaminol; subst.c. = ? µmol/l

Plasma— Urine— Griseofulvin; antagonist; substance concentration arbitrary concentration(list; procedure) mole/liter NPU04586 M = 352,77 g/mol U—Histamine antagonist; arb.c.(list; proc.) NPU04803 NPU01269 U—Antazoline; arb.c.(proc.) = ? P—Griseofulvin; subst.c.= ? prefix ? mol/l NPU01906 U—Diphenhydramine; arb.c.(proc.) = ? NPU02698 U—; arb.c.(proc.) = ? Urine— NPU03263 U—; arb.c.(proc.) = ? Griseofulvin; substance concentration Urine— mole/liter Histamine antagonist; M = 352,77 g/mol taxon(procedure) NPU04395 NPU04825 U—Griseofulvin; subst.c.= ? prefix ? mol/l U—Histamine antagonist; taxon(proc.) = ?

Urine— Urine— Haemoleptic agent; Hydralazine; arbitrary concentration(list; procedure) arbitrary concentration(procedure) NPU08594 M = 168,18 g/mol U—Haemoleptic agent; arb.c.(list; proc.) NPU04396 U—Hydralazine; arb.c.(proc.) = ?

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Urine— Urine— Hydralazine; Hydroflumethiazide; substance concentration substance concentration mole/liter micromole/liter M = 168,18 g/mol M = 331,29 g/mol NPU04397 NPU04470 U—Hydralazine; subst.c.= ? prefix ? mol/l U—Hydroflumethiazide; subst.c. = ? µmol/l

Plasma— Urine— Hydralazine; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 285,33 g/mol M = 168,18 g/mol NPU04693 NPU04398 U—Hydromorphone; arb.c.(proc.) = ? P—Hydralazine; subst.c. = ? nmol/l Plasma— Urine— Hydromorphone; ; substance concentration arbitrary concentration(procedure) mole/liter M = 297,72 g/mol M = 285,33 g/mol NPU02404 NPU04399 U—Hydrochlorothiazide; arb.c.(proc.) = ? P—Hydromorphone; subst.c.= ? prefix ? mol/l

Plasma— Urine— Hydrochlorothiazide; Hydromorphone; substance concentration substance concentration micromole/liter mole/liter M = 297,72 g/mol M = 285,33 g/mol NPU08793 NPU04473 P—Hydrochlorothiazide; subst.c. = ? µmol/l U—Hydromorphone; subst.c.= ? prefix ? mol/l

Urine— Urine— Hydrochlorothiazide; p- substance concentration Hydroxyamfetamine; micromole/liter arbitrary concentration(procedure) M = 297,72 g/mol M = 151,21 g/mol NPU02407 Other term(s): Methylthyramine U—Hydrochlorothiazide; subst.c. = ? µmol/l NPU04492 U—p-Hydroxyamfetamine; arb.c.(proc.) = ? Urine— Hydrocodone; Urine— arbitrary concentration(procedure) p- M = 299,36 g/mol Hydroxyamfetamine; NPU02408 substance concentration U—Hydrocodone; arb.c.(proc.) = ? micromole/liter M = 151,21 g/mol Urine— Other term(s): Methylthyramine Hydrocodone; NPU02421 substance concentration U—p-Hydroxyamfetamine; subst.c. = ? µmol/l mole/liter M = 299,36 g/mol Plasma— NPU04924 7- U—Hydrocodone; subst.c.= ? prefix ? mol/l Hydroxyamoxapine; substance concentration Urine— nanomole/liter Hydroflumethiazide; NPU10268 arbitrary concentration(procedure) P—7-Hydroxyamoxapine; subst.c. = ? nmol/l M = 331,29 g/mol NPU04597 U—Hydroflumethiazide; arb.c.(proc.) = ?

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Plasma— Plasma— 8- ; Hydroxyamoxapine; substance concentration substance concentration micromole/liter nanomole/liter M = 206,27 g/mol NPU10269 NPU08794 P—8-Hydroxyamoxapine; subst.c. = ? nmol/l P—Ibuprofen; subst.c. = ? µmol/l

Plasma— Patient— 10- Imipramine(administered); Hydroxycarbamazepine; substance rate(oral administration) substance concentration micromole/day micromole/liter M = 280,41 g/mol NPU10615 NPU10244 P—10-Hydroxycarbamazepine; subst.c. = ? µmol/l Pt—Imipramine(administered); subst.rate(p.o.) = ? µmol/d Urine— 6-b- Urine— Hydroxymetandienone; Imipramine; arbitrary concentration(procedure) arbitrary concentration(procedure) NPU08597 M = 280,41 g/mol U—6-b-Hydroxymetandienone; arb.c.(proc.) = ? NPU02473 U—Imipramine; arb.c.(proc.) = ? Plasma— 10- Plasma— Hydroxynortriptyline; Imipramine; substance concentration substance concentration nanomole/liter nanomole/liter NPU09093 M = 280,41 g/mol P—10-Hydroxynortriptyline; subst.c. = ? nmol/l NPU02472 P—Imipramine; subst.c. = ? nmol/l Urine— 3'- Urine— Hydroxystanozolol; Imipramine; arbitrary concentration(procedure) substance concentration NPU08598 nanomole/liter U—3'-Hydroxystanozolol; arb.c.(proc.) = ? M = 280,41 g/mol NPU04798 Urine— U—Imipramine; subst.c. = ? nmol/l ; arbitrary concentration(procedure) Plasma— M = 374,92 g/mol Imipramine+Desipramine; NPU09053 substance concentration U—Hydroxyzine; arb.c.(proc.) = ? nanomole/liter Note: M (imipramine) = 280,41 g/mol; M Plasma— (desipramine) = 266,37 g/mol Hydroxyzine; NPU08627 substance concentration P—Imipramine+Desipramine; subst.c. = ? nmol/l mole/liter M = 374,92 g/mol Urine— NPU09051 ; P—Hydroxyzine; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) M = 296,41 g/mol Urine— Other term(s): Imipramine N-oxide Hydroxyzine; NPU09076 substance concentration U—Imipraminoxide; arb.c.(proc.) = ? mole/liter M = 374,92 g/mol NPU09052 U—Hydroxyzine; subst.c.= ? prefix ? mol/l

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Plasma— Plasma— Imipraminoxide; Isoniazide; substance concentration substance concentration mole/liter micromole/liter M = 296,41 g/mol M = 137,15 g/mol Other term(s): Imipramine N-oxide NPU04816 NPU09074 P—Isoniazide; subst.c. = ? µmol/l P—Imipraminoxide; subst.c.= ? prefix ? mol/l Urine— Urine— Isoniazide; Imipraminoxide; substance concentration substance concentration micromole/liter mole/liter NPU16482 M = 296,41 g/mol U—Isoniazide; subst.c. = ? µmol/l Other term(s): Imipramine N-oxide NPU09075 Plasma— U—Imipraminoxide; subst.c.= ? prefix ? mol/l Isopropanol; substance concentration Urine— millimole/liter ; M = 60,10 g/mol substance concentration NPU08796 mole/liter P—Isopropanol; subst.c. = ? mmol/l M = 365,84 g/mol NPU04496 Plasma— U—Indapamide; subst.c.= ? prefix ? mol/l ; substance concentration Plasma— nanomole/liter ; M = 371,39 g/mol substance concentration NPU08797 mole/liter P—Isradipine; subst.c. = ? nmol/l M = 357,81 g/mol NPU08795 Urine— P—Indometacin; subst.c.= ? prefix ? mol/l Ketobemidone; arbitrary concentration(procedure) Urine— M = 247,33 g/mol ; NPU02523 arbitrary concentration(procedure) U—Ketobemidone; arb.c.(proc.) = ? M = 231,25 g/mol NPU09079 Plasma— U—Isocarboxazid; arb.c.(proc.) = ? Ketobemidone; substance concentration Plasma— micromole/liter Isocarboxazid; M = 247,33 g/mol substance concentration NPU08798 mole/liter P—Ketobemidone; subst.c. = ? µmol/l M = 231,25 g/mol NPU09077 Urine— P—Isocarboxazid; subst.c.= ? prefix ? mol/l Ketobemidone; substance concentration Urine— micromole/liter Isocarboxazid; M = 247,33 g/mol substance concentration NPU02524 mole/liter U—Ketobemidone; subst.c. = ? µmol/l M = 231,25 g/mol NPU09078 Urine— U—Isocarboxazid; subst.c.= ? prefix ? mol/l Labetalol; arbitrary concentration(procedure) M = 328,41 g/mol NPU04697 U—Labetalol; arb.c.(proc.) = ?

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Plasma— Urine— Labetalol; Levorphanol; substance concentration arbitrary concentration(procedure) micromole/liter M = 257,38 g/mol M = 328,41 g/mol NPU04497 NPU04234 U—Levorphanol; arb.c.(proc.) = ? P—Labetalol; subst.c. = ? µmol/l Urine— Urine— Levorphanol; Labetalol; substance concentration substance concentration micromole/liter micromole/liter M = 257,38 g/mol M = 328,41 g/mol NPU02601 NPU02540 U—Levorphanol; subst.c. = ? µmol/l U—Labetalol; subst.c. = ? µmol/l Plasma— Patient— ; (administered); substance concentration substance rate(oral administration) micromole/liter micromole/day M = 234,34 g/mol M = 256,09 g/mol NPU02602 NPU10245 P—Lidocaine; subst.c. = ? µmol/l Pt—Lamotrigine(administered); subst.rate(p.o.) = ? µmol/d Urine— ; Plasma— arbitrary concentration(procedure) Lamotrigine; M = 408,54 g/mol substance concentration NPU04235 micromole/liter U—Lofentanil; arb.c.(proc.) = ? M = 256,09 g/mol NPU08732 Plasma— P—Lamotrigine; subst.c. = ? µmol/l Lofentanil; substance concentration Urine— mole/liter ; M = 408,54 g/mol arbitrary concentration(procedure) NPU04237 M = 328,46 g/mol P—Lofentanil; subst.c.= ? prefix ? mol/l NPU02598 U—Levomepromazine; arb.c.(proc.) = ? Urine— Lofentanil; Urine— substance concentration Levomepromazine; mole/liter substance concentration M = 408,54 g/mol micromole/liter NPU04236 M = 328,46 g/mol U—Lofentanil; subst.c.= ? prefix ? mol/l NPU04800 U—Levomepromazine; subst.c. = ? µmol/l Urine— ; Plasma— arbitrary concentration(procedure) Levomepromazine; M = 418,97 g/mol substance concentration NPU09081 nanomole/liter U—Lofepramine; arb.c.(proc.) = ? M = 328,46 g/mol NPU04853 Plasma— P—Levomepromazine; subst.c. = ? nmol/l Lofepramine; substance concentration nanomole/liter M = 418,97 g/mol NPU04854 P—Lofepramine; subst.c. = ? nmol/l

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Urine— Urine— Lofepramine; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 327,81 g/mol M = 418,97 g/mol NPU04238 NPU09080 U—Loxapine; arb.c.(proc.) = ? U—Lofepramine; subst.c. = ? nmol/l Plasma— Urine— Loxapine; Lorazepam; substance concentration arbitrary concentration(procedure) mole/liter M = 321,16 g/mol M = 327,81 g/mol NPU02614 NPU04240 U—Lorazepam; arb.c.(proc.) = ? P—Loxapine; subst.c.= ? prefix ? mol/l

Urine— Urine— Lorazepam; Loxapine; substance concentration substance concentration micromole/liter mole/liter M = 321,16 g/mol M = 327,81 g/mol NPU04699 NPU04239 U—Lorazepam; subst.c. = ? µmol/l U—Loxapine; subst.c.= ? prefix ? mol/l

Plasma— Urine— Lorazepam; Lysergide; substance concentration arbitrary concentration(procedure) nanomole/liter M = 323,44 g/mol M = 321,16 g/mol Other term(s): LSD NPU04855 NPU04932 P—Lorazepam; subst.c. = ? nmol/l U—Lysergide; arb.c.(proc.) = ?

Urine— Urine— ; Lysergide; arbitrary concentration(procedure) substance concentration M = 335,19 g/mol mole/liter NPU02615 M = 323,44 g/mol U—Lormetazepam; arb.c.(proc.) = ? Other term(s): LSD NPU04933 Urine— U—Lysergide; subst.c.= ? prefix ? mol/l Lormetazepam; substance concentration Urine— micromole/liter Lyserginate; M = 335,19 g/mol arbitrary concentration(procedure) NPU09064 Note: M(anion) = 267,31 g/mol U—Lormetazepam; subst.c. = ? µmol/l NPU04930 U—Lyserginate; arb.c.(proc.) = ? Plasma— Lormetazepam; Urine— substance concentration Lyserginate; nanomole/liter substance concentration M = 335,19 g/mol mole/liter NPU09065 Note: M (anion) = 267,31 g/mol P—Lormetazepam; subst.c. = ? nmol/l NPU04931 U—Lyserginate; subst.c.= ? prefix ? mol/l Patient— (administered); Urine— substance rate(oral administration) Mannitol; millimole/day arbitrary concentration(procedure) M = 404,55 g/mol M = 182,17 g/mol NPU10190 NPU04515 Pt—Lovastatin(administered); subst.rate(p.o.) = ? U—Mannitol; arb.c.(proc.) = ? mmol/d

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Urine— Urine— Mannitol; ; substance concentration arbitrary concentration(procedure) mole/liter M = 270,76 g/mol M = 182,17 g/mol NPU02689 NPU09344 U—Medazepam; arb.c.(proc.) = ? U—Mannitol; subst.c.= ? prefix ? mol/l Urine— Urine— ; Maprotiline; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 211,73 g/mol M = 277,41 g/mol NPU04498 NPU02688 U—Mefenorex; arb.c.(proc.) = ? U—Maprotiline; arb.c.(proc.) = ? Urine— Urine— Mefenorex; Maprotiline; substance concentration substance concentration micromole/liter micromole/liter M = 211,74 g/mol M = 277,41 g/mol NPU02694 NPU04802 U—Mefenorex; subst.c. = ? µmol/l U—Maprotiline; subst.c. = ? µmol/l Urine— Plasma— ; Maprotiline; substance concentration substance concentration mole/liter nanomole/liter M = 382,90 g/mol M = 277,41 g/mol NPU04499 NPU04857 U—Mefruside; subst.c.= ? prefix ? mol/l P—Maprotiline; subst.c. = ? nmol/l Urine— Urine— ; Meclozine; substance concentration arbitrary concentration(procedure) mole/liter M = 390,96 g/mol M = 163,25 g/mol Other term(s): NPU04500 NPU04241 U—Mephentermine; subst.c.= ? prefix ? mol/l U—Meclozine; arb.c.(proc.) = ? Urine— Plasma— Mepindolol; Meclozine; arbitrary concentration(procedure) substance concentration M = 262,36 g/mol mole/liter NPU04503 M = 390,96 g/mol U—Mepindolol; arb.c.(proc.) = ? Other term(s): Meclizine NPU04243 Urine— P—Meclozine; subst.c.= ? prefix ? mol/l ; arbitrary concentration(procedure) Urine— M = 218,25 g/mol Meclozine; NPU02697 substance concentration U—Meprobamate; arb.c.(proc.) = ? mole/liter M = 390,96 g/mol Plasma— Other term(s): Meclizine Meprobamate; NPU04242 substance concentration U—Meclozine; subst.c.= ? prefix ? mol/l micromole/liter M = 218,25 g/mol NPU02696 P—Meprobamate; subst.c. = ? µmol/l

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Urine— Urine— Meprobamate; ; substance concentration substance concentration micromole/liter mole/liter M = 218,25 g/mol M = 304,46 g/mol NPU03413 NPU04518 U—Meprobamate; subst.c. = ? µmol/l U—Mestanolone; subst.c.= ? prefix ? mol/l

Urine— Urine— Mepyramine; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 285,39 g/mol M = 304,46 g/mol NPU02698 NPU04519 U—Mepyramine; arb.c.(proc.) = ? U—Mesterolone; arb.c.(proc.) = ?

Urine— Urine— Mepyramine; Mesterolone; substance concentration substance concentration micromole/liter nanomole/liter M = 285,39 g/mol M = 304,46 g/mol NPU04804 NPU02708 U—Mepyramine; subst.c. = ? µmol/l U—Mesterolone; subst.c. = ? nmol/l

Urine— Urine— ; Metamfetamine; substance concentration arbitrary concentration(procedure) micromole/liter M = 149,24 g/mol M = 505,85 g/mol NPU04520 NPU02705 U—Metamfetamine; arb.c.(proc.) = ? U—Mersalyl; subst.c. = ? µmol/l Urine— Urine— Metamfetamine; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 386,59 g/mol M = 149,24 g/mol NPU04244 NPU02711 U—Mesoridazine; arb.c.(proc.) = ? U—Metamfetamine; subst.c. = ? µmol/l

Plasma— Urine— Mesoridazine; ; substance concentration arbitrary concentration(procedure) mole/liter M = 300,42 g/mol M = 386,59 g/mol Other term(s): Methandrostenolone NPU04246 NPU04521 P—Mesoridazine; subst.c.= ? prefix ? mol/l U—Metandienone; arb.c.(proc.) = ?

Urine— Urine— Mesoridazine; Metandienone; substance concentration substance concentration mole/liter nanomole/liter M = 386,59 g/mol M = 300,42 g/mol NPU04245 Other term(s): Methandrostenolone U—Mesoridazine; subst.c.= ? prefix ? mol/l NPU02714 U—Metandienone; subst.c. = ? nmol/l Urine— Mestanolone; arbitrary concentration(procedure) M = 304,46 g/mol NPU04937 U—Mestanolone; arb.c.(proc.) = ?

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Urine— Urine— ; Methadone; arbitrary concentration(procedure) substance concentration M = 167,21 g/mol nanomole/liter Other term(s): Hydroxynor(pseudo)ephedrine M = 309,45 g/mol NPU04710 NPU02721 U—Metaraminol; arb.c.(proc.) = ? U—Methadone; subst.c. = ? nmol/l

Plasma— Urine— Metaraminol; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 304,46 g/mol M = 167,21 g/mol NPU04505 Other term(s): Hydroxynor(pseudo)ephedrine U—Methandriol; arb.c.(proc.) = ? NPU04247 P—Metaraminol; subst.c. = ? nmol/l Urine— Methandriol; Urine— substance concentration Metaraminol; mole/liter substance concentration M = 304,46 g/mol nanomole/liter NPU04908 M = 167,21 g/mol U—Methandriol; subst.c.= ? prefix ? mol/l Other term(s): Hydroxynor(pseudo)ephedrine NPU02715 Urine— U—Metaraminol; subst.c. = ? nmol/l ; arbitrary concentration(procedure) Urine— M = 250,29 g/mol ; NPU02724 arbitrary concentration(procedure) U—Methaqualone; arb.c.(proc.) = ? M = 302,44 g/mol NPU04504 Plasma— U—Metenolone; arb.c.(proc.) = ? Methaqualone; substance concentration Urine— micromole/liter Metenolone; M = 250,29 g/mol substance concentration NPU04836 nanomole/liter P—Methaqualone; subst.c. = ? µmol/l M = 302,44 g/mol Other term(s): Methenolone Urine— NPU02718 Methaqualone; U—Metenolone; subst.c. = ? nmol/l substance concentration micromole/liter Urine— M = 250,29 g/mol Methadone; NPU03490 arbitrary concentration(procedure) U—Methaqualone; subst.c. = ? µmol/l M = 309,45 g/mol NPU02722 Urine— U—Methadone; arb.c.(proc.) = ? ; arbitrary concentration(procedure) Plasma— M = 262,31 g/mol Methadone; NPU08801 substance concentration U—Methohexital; arb.c.(proc.) = ? nanomole/liter M = 309,45 g/mol Plasma— NPU04113 Methohexital; P—Methadone; subst.c. = ? nmol/l substance concentration mole/liter M = 262,31 g/mol NPU08803 P—Methohexital; subst.c.= ? prefix ? mol/l

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Urine— Urine— Methohexital; 3,4- substance concentration Methylenedioxyamfetamine; mole/liter substance concentration M = 262,31 g/mol micromole/liter NPU08802 M = 179,25 g/mol U—Methohexital; subst.c.= ? prefix ? mol/l Other term(s): MDA NPU04925 Plasma— U—3,4-Methylenedioxyamfetamine; subst.c. = ? Methoxsalen; µmol/l substance concentration mole/liter Urine— M = 216,18 g/mol 3,4- NPU08799 Methylenedioxyethylamfetamine; P—Methoxsalen; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) M = 207,27 g/mol Urine— Other term(s): MDEA ; NPU08923 arbitrary concentration(procedure) U—3,4-Methylenedioxyethylamfetamine; M = 179,25 g/mol arb.c.(proc.) = ? NPU04530 U—Methoxyphenamine; arb.c.(proc.) = ? Urine— 3,4- Urine— Methylenedioxyethylamfetamine; Methoxyphenamine; substance concentration substance concentration micromole/liter micromole/liter M = 207,27 g/mol M = 179,25 g/mol Other term(s): MDEA NPU02743 NPU08924 U—Methoxyphenamine; subst.c. = ? µmol/l U—3,4-Methylenedioxyethylamfetamine; subst.c. = ? µmol/l Urine— 2- Urine— Methylamino-1(3,4-methylenedioxyphenyl); 3,4- arbitrary concentration(procedure) Methylenedioxymetamfetamine; M = 207,27 g/mol arbitrary concentration(procedure) Other term(s): MBDB M = 193,25 g/mol NPU08921 Other term(s): MDMA; Ecstasy U—2-Methylamino-1(3,4- NPU04701 methylenedioxyphenyl)butane; arb.c.(proc.) = ? U—3,4-Methylenedioxymetamfetamine; arb.c.(proc.) = ? Urine— 2- Urine— Methylamino-1(3,4-methylenedioxyphenyl)butane; 3,4- substance concentration Methylenedioxymetamfetamine; micromole/liter substance concentration M = 207,27 g/mol micromole/liter Other term(s): MBDB M = 193,25 g/mol NPU08922 Other term(s): MDMA; Ecstasy U—2-Methylamino-1(3,4- NPU04482 methylenedioxyphenyl)butane; subst.c. = ? µmol/l U—3,4-Methylenedioxymetamfetamine; subst.c. = ? µmol/l Urine— 3,4- Urine— Methylenedioxyamfetamine; Methylephedrine; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 179,22 g/mol M = 179,25 g/mol Other term(s): MDA Authority: BAN NPU04927 NPU04533 U—3,4-Methylenedioxyamfetamine; arb.c.(proc.) = ? U—Methylephedrine; arb.c.(proc.) = ?

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Urine— Plasma— Methylephedrine; ; substance concentration substance concentration micromole/liter mole/liter M = 179,25 g/mol M = 445,61 g/mol Authority: BAN NPU08804 NPU02774 P—Metopimazine; subst.c.= ? prefix ? mol/l U—Methylephedrine; subst.c. = ? µmol/l Urine— Urine— Metoprolol; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 267,38 g/mol M = 233,30 g/mol NPU04616 NPU04516 U—Metoprolol; arb.c.(proc.) = ? U—Methylphenidate; arb.c.(proc.) = ? Plasma— Urine— Metoprolol; Methylphenidate; substance concentration substance concentration micromole/liter micromole/liter M = 267,38 g/mol M = 233,30 g/mol NPU04858 NPU02800 P—Metoprolol; subst.c. = ? µmol/l U—Methylphenidate; subst.c. = ? µmol/l Urine— Urine— Metoprolol; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 302,44 g/mol M = 267,38 g/mol NPU04517 NPU02815 U—Methyltestosterone; arb.c.(proc.) = ? U—Metoprolol; subst.c. = ? µmol/l

Urine— Plasma— Methyltestosterone; Metronidazole; substance concentration substance concentration nanomole/liter mole/liter M = 302,44 g/mol M = 171,16 g/mol NPU02803 NPU08805 U—Methyltestosterone; subst.c. = ? nmol/l P—Metronidazole; subst.c.= ? prefix ? mol/l

Urine— Plasma— ; ; arbitrary concentration(procedure) substance concentration M = 183,26 g/mol micromole/liter NPU02812 M = 179,27 g/mol U—Methyprylon; arb.c.(proc.) = ? NPU04859 P—Mexiletine; subst.c. = ? µmol/l Urine— Meticillin; Urine— arbitrary concentration(procedure) Mianserin; M = 402,40 g/mol arbitrary concentration(procedure) NPU10189 M = 264,37 g/mol U—Meticillin; arb.c.(proc.) = ? NPU02816 U—Mianserin; arb.c.(proc.) = ? Plasma— ; Urine— substance concentration Mianserin; mole/liter substance concentration M = 299,80 g/mol micromole/liter NPU08800 M = 264,37 g/mol P—Metoclopramide; subst.c.= ? prefix ? mol/l NPU04806 U—Mianserin; subst.c. = ? µmol/l

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Plasma— Urine— Mianserin; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 268,74 g/mol M = 264,37 g/mol NPU09083 NPU04860 U—Moclobemide; arb.c.(proc.) = ? P—Mianserin; subst.c. = ? nmol/l Plasma— Urine— Moclobemide; ; substance concentration arbitrary concentration(procedure) nanomole/liter M = 302,46 g/mol M = 268,74 g/mol NPU04938 NPU08953 U—Mibolerone; arb.c.(proc.) = ? P—Moclobemide; subst.c. = ? nmol/l

Urine— Urine— Mibolerone; Moclobemide; substance concentration substance concentration micromole/liter nanomole/liter M = 302,46 g/mol M = 268,74 g/mol NPU04910 NPU09082 U—Mibolerone; subst.c. = ? µmol/l U—Moclobemide; subst.c. = ? nmol/l

Urine— Urine— ; 6- arbitrary concentration(procedure) Monoacetylmorphine; M = 325,77 g/mol arbitrary concentration(procedure) NPU04248 M = 327,38 g/mol U—Midazolam; arb.c.(proc.) = ? NPU08927 U—6-Monoacetylmorphine; arb.c.(proc.) = ? Plasma— Midazolam; Urine— substance concentration 6- nanomole/liter Monoacetylmorphine; M = 325,77 g/mol substance concentration NPU04250 mole/liter P—Midazolam; subst.c. = ? nmol/l M = 327,38 g/mol NPU08928 Urine— U—6-Monoacetylmorphine; subst.c.= ? prefix ? Midazolam; mol/l substance concentration nanomole/liter Urine— M = 325,77 g/mol ; NPU04249 arbitrary concentration(procedure) U—Midazolam; subst.c. = ? nmol/l M = 377,47 g/mol NPU04524 Plasma— U—Morazone; arb.c.(proc.) = ? ; substance concentration Urine— nanomole/liter Morazone; M = 300,81 g/mol substance concentration NPU14028 micromole/liter P—Mirtazapine; subst.c. = ? nmol/l M = 377,47 g/mol NPU02844 Plasma— U—Morazone; subst.c. = ? µmol/l Mivacurium; substance concentration nanomole/liter M = 1 029,275 g/mol NPU04590 P—Mivacurium; subst.c. = ? nmol/l

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Urine— Urine— Morphine(non-complexed); Morphine+analogue(non-complexed); arbitrary concentration(procedure) arbitrary concentration(procedure) M = 285,34 g/mol Note: Morphine; Morphine-3-glucuronide; Morphine- Authority: BAN 6-glucuronide; Codeine; Diamorphine; NPU02846 Dihydrocodeine; Ethylmorphine; Hydrocodone; U—Morphine(non-complexed); arb.c.(proc.) = ? Hydromorphone; ; Levophanol; ; Normorphine; Oxycodone Urine— NPU08954 Morphine(non-complexed); U—Morphine+analogue(non-complexed); substance concentration arb.c.(proc.) = ? micromole/liter M = 285,34 g/mol Urine— Authority: BAN Morphine+analogue(non-complexed); NPU02849 substance concentration U—Morphine(non-complexed); subst.c. = ? µmol/l micromole/liter Note: Morphine; Morphine-3-glucuronide; Morphine- Urine— 6-glucuronide; Codeine; Diamorphine; Morphine(total); Dihydrocodeine; Ethylmorphine; Hydrocodone; arbitrary concentration(procedure) Hydromorphone; Levallorphan; Levophanol; M = 285,34 g/mol Nalorphine; Normorphine; Oxycodone Authority: BAN NPU08988 Note: Total: non-glucuronidated and glucuronidated U—Morphine+analogue(non-complexed); NPU08985 subst.c. = ? µmol/l U—Morphine(tot.); arb.c.(proc.) = ? Urine— Plasma— Morphine+analogue; Morphine(total); arbitrary concentration(procedure) substance concentration Note: Morphine; Morphine-3-glucuronide; Morphine- micromole/liter 6-glucuronide; Codeine; Diamorphine; M = 285,34 g/mol Dihydrocodeine; Ethylmorphine; Hydrocodone; Authority: BAN Hydromorphone; Levallorphan; Levophanol; Note: Total: non-glucuronidated and glucuronidated Nalorphine; Normorphine; Oxycodone NPU09345 NPU08990 P—Morphine(tot.); subst.c. = ? µmol/l U—Morphine+analogue; arb.c.(proc.) = ?

Urine— Urine— Morphine(total); Morphine+analogue; substance concentration substance concentration micromole/liter micromole/liter M = 285,34 g/mol Note: Morphine; Morphine-3-glucuronide; Morphine- Authority: BAN 6-glucuronide; Codeine; Diamorphine; Note: Total: non-glucuronidated and glucuronidated Dihydrocodeine; Ethylmorphine; Hydrocodone; NPU08986 Hydromorphone; Levallorphan; Levophanol; U—Morphine(tot.); subst.c. = ? µmol/l Nalorphine; Normorphine; Oxycodone NPU08992 Plasma— U—Morphine+analogue; subst.c. = ? µmol/l Morphine(total); substance concentration Urine— nanomole/liter Morphine+analogue; M = 285,34 g/mol taxon(procedure) Authority: BAN Note: Morphine; Morphine-3-glucuronide; Morphine- Note: Total: non-glucuronidated and glucuronidated 6-glucuronide; Codeine; Diamorphine; NPU10619 Dihydrocodeine; Ethylmorphine; Hydrocodone; P—Morphine(tot.); subst.c. = ? nmol/l Hydromorphone; Levallorphan; Levophanol; Nalorphine; Normorphine; Oxycodone NPU08991 U—Morphine+analogue; taxon(proc.) = ?

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Urine— Urine— Nadolol; Narcotic drug; arbitrary concentration(procedure) arbitrary concentration(list; procedure) M = 309,42 g/mol NPU08766 NPU04555 U—Narcotic drug; arb.c.(list; proc.) U—Nadolol; arb.c.(proc.) = ? NPU01163 U—Amfetamine; arb.c.(proc.) = ? NPU08957 U—Cannabinol; arb.c.(proc.) = ? Urine— NPU01706 U—Cocaine; arb.c.(proc.) = ? Nadolol; NPU02523 U—Ketobemidone; arb.c.(proc.) = ? substance concentration NPU02722 U—Methadone; arb.c.(proc.) = ? micromole/liter NPU08985 U—Morphine(tot.); arb.c.(proc.) = ? M = 309,42 g/mol NPU08990 U—Morphine+analogue; arb.c. NPU02873 (proc.) = ? U—Nadolol; subst.c. = ? µmol/l Urine— Urine— Narcotic drug; Nalbuphine; taxon(procedure) arbitrary concentration(procedure) NPU08930 M = 357,46 g/mol U—Narcotic drug; taxon(proc.) = ? NPU04536 U—Nalbuphine; arb.c.(proc.) = ? Plasma— ; Urine— substance concentration Nalbuphine; nanomole/liter substance concentration M = 470,01 g/mol micromole/liter NPU14029 M = 357,46 g/mol P—Nefazodone; subst.c. = ? nmol/l NPU02884 U—Nalbuphine; subst.c. = ? µmol/l Urine— Neopterine; Urine— arbitrary concentration(procedure) Nalorphine; M = 253,22 g/mol arbitrary concentration(procedure) NPU04563 M = 311,38 g/mol U—Neopterine; arb.c.(proc.) = ? NPU04928 U—Nalorphine; arb.c.(proc.) = ? Cerebrospinal fluid— Neopterine; Urine— substance concentration Nalorphine; nanomole/liter substance concentration M = 253,22 g/mol mole/liter NPU12535 M = 311,38 g/mol Csf—Neopterine; subst.c. = ? nmol/l NPU04929 U—Nalorphine; subst.c.= ? prefix ? mol/l Plasma— Neopterine; Urine— substance concentration ; nanomole/liter arbitrary concentration(procedure) M = 253,22 g/mol M = 274,39 g/mol NPU12533 NPU04539 P—Neopterine; subst.c. = ? nmol/l U—Nandrolone; arb.c.(proc.) = ? Urine— Urine— Neopterine; Nandrolone; substance concentration substance concentration nanomole/liter nanomole/liter M = 253,22 g/mol M = 274,39 g/mol NPU02892 NPU02887 U—Neopterine; subst.c. = ? nmol/l U—Nandrolone; subst.c. = ? nmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 531

Plasma— Urine— Netilmicin; Neuroleptic drug; arbitrary concentration(procedure) taxon(procedure) NPU12364 NPU08931 P—Netilmicin; arb.c.(proc.) = ? U—Neuroleptic drug; taxon(proc.) = ?

Cerebrospinal fluid— Urine— Netilmicin; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 495,51 g/mol NPU12928 NPU02908 Csf—Netilmicin; subst.c. = ? µmol/l U—Nicomorphine; arb.c.(proc.) = ?

Plasma— Urine— Netilmicin; Nicomorphine; substance concentration substance concentration micromole/liter mole/liter M = 475,59 g/mol M = 495,51 g/mol NPU02893 NPU04911 P—Netilmicin; subst.c. = ? µmol/l U—Nicomorphine; subst.c.= ? prefix ? mol/l

Secretion(specification)— Urine— Netilmicin; ; substance concentration substance concentration micromole/liter mole/liter NPU12927 M = 122,1 g/mol Secr(spec.)—Netilmicin; subst.c. = ? µmol/l Other term(s): Niacinamide NPU02909 System(specification)— U—Nicotinamide; subst.c.= ? prefix ? mol/l Netilmicin; substance concentration Urine— micromole/liter Nicotinate; NPU17527 arbitrary concentration(procedure) Syst(spec.)—Netilmicin; subst.c. = ? µmol/l Note: M (anion) = 122,11 g/mol NPU04541 Urine— U—Nicotinate; arb.c.(proc.) = ? Netilmicin; substance concentration Urine— micromole/liter Nicotinate; NPU12926 substance concentration U—Netilmicin; subst.c. = ? µmol/l mole/liter Note: M (anion) = 122,11 g/mol Urine— NPU02911 Neuroleptic drug; U—Nicotinate; subst.c.= ? prefix ? mol/l arbitrary substance concentration(list; procedure) Urine— NPU08767 ; U—Neuroleptic drug; arb.subst.c.(list; proc.) arbitrary concentration(procedure) NPU01544 U—Chlorpromazine; arb.c.(proc.) = ? M = 162,23 g/mol NPU01545 U—Chlorprothixene; arb.c.(proc.) = ? Authority: Martindale NPU02598 U—Levomepromazine; arb.c.(proc.) = ? NPU04540 NPU03262 U—; arb.c.(proc.) = ? U—Nicotine; arb.c.(proc.) = ? NPU04644 U—; arb.c.(proc.) = ? Urine— System(specification)— Nicotine; Neuroleptic drug; substance concentration taxon(procedure) mole/liter Authority: QU60883 M = 162,23 g/mol NPU10281 Authority: Martindale Syst(spec.)—Neuroleptic drug; taxon(proc.) = ? NPU02910 U—Nicotine; subst.c.= ? prefix ? mol/l

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Urine— Urine— Nifenalol; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 224,26 g/mol M = 331,46 g/mol NPU04542 NPU04251 U—Nifenalol; arb.c.(proc.) = ? U—Nizatidine; arb.c.(proc.) = ?

Urine— Plasma— ; Nizatidine; arbitrary concentration(procedure) substance concentration M = 178,23 g/mol micromole/liter NPU04543 M = 331,46 g/mol U—Nikethamide; arb.c.(proc.) = ? NPU04253 P—Nizatidine; subst.c. = ? µmol/l Urine— Nikethamide; Urine— substance concentration Nizatidine; micromole/liter substance concentration M = 178,23 g/mol micromole/liter NPU02914 M = 331,46 g/mol U—Nikethamide; subst.c. = ? µmol/l NPU04252 U—Nizatidine; subst.c. = ? µmol/l Urine— Nitrazepam; Plasma— arbitrary concentration(procedure) ; M = 281,27 g/mol substance concentration NPU02916 nanomole/liter U—Nitrazepam; arb.c.(proc.) = ? Other term(s): Desmethyldiazepam NPU10303 Urine— P—Nordazepam; subst.c. = ? nmol/l Nitrazepam; substance concentration Urine— micromole/liter ; M = 281,27 g/mol arbitrary concentration(procedure) NPU04723 M = 302,44 g/mol U—Nitrazepam; subst.c. = ? µmol/l NPU04565 U—Norethandrolone; arb.c.(proc.) = ? Plasma— Nitrazepam; Urine— substance concentration Norethandrolone; nanomole/liter substance concentration M = 281,27 g/mol nanomole/liter NPU02915 M = 302,44 g/mol P—Nitrazepam; subst.c. = ? nmol/l NPU02920 U—Norethandrolone; subst.c. = ? nmol/l Urine— Nitrofurantoin; Urine— arbitrary concentration(procedure) ; M = 238,16 g/mol arbitrary concentration(procedure) NPU10194 M = 153,18 g/mol U—Nitrofurantoin; arb.c.(proc.) = ? NPU04567 U—Norfenefrine; arb.c.(proc.) = ? Plasma— Nitroglycerin; Urine— substance concentration Norfenefrine; mole/liter substance concentration M = 227,09 g/mol mole/liter Other term(s): Glyceryl(tri)nitrate M = 153,18 g/mol NPU08792 NPU02921 P—Nitroglycerin; subst.c.= ? prefix ? mol/l U—Norfenefrine; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 533

Urine— Urine— ; ; substance concentration substance concentration micromole/liter mole/liter M = 203,21 g/mol M = 153,18 g/mol NPU04568 NPU02927 U—Norfenfluramine; subst.c. = ? µmol/l U—Octopamine; subst.c.= ? prefix ? mol/l

Plasma— Plasma— Norfluoxetine; ; substance concentration substance concentration nanomole/liter nanomole/liter NPU17886 M = 312,44 g/mol P—Norfluoxetine; subst.c. = ? nmol/l NPU09358 P—Olanzapine; subst.c.= ? nmol/l Urine— ; Plasma— arbitrary concentration(procedure) ; M = 233,30 g/mol substance concentration NPU04571 nanomole/liter U—Norpethidine; arb.c.(proc.) = ? M = 363,49 g/mol NPU04837 Urine— P—Opipramol; subst.c. = ? nmol/l Norpethidine; substance concentration Urine— mole/liter ; M = 233,30 g/mol arbitrary concentration(procedure) NPU02922 M = 306,43 g/mol U—Norpethidine; subst.c.= ? prefix ? mol/l NPU04726 U—Oxandrolone; arb.c.(proc.) = ? Plasma— Norpropoxyphen; Plasma— substance concentration Oxandrolone; micromole/liter substance concentration NPU10766 nanomole/liter P—Norpropoxyphen; subst.c. = ? µmol/l M = 306,43 g/mol NPU04254 Urine— P—Oxandrolone; subst.c. = ? nmol/l Nortriptyline; arbitrary concentration(procedure) Urine— M = 263,38 g/mol Oxandrolone; NPU02924 substance concentration U—Nortriptyline; arb.c.(proc.) = ? nanomole/liter M = 306,43 g/mol Plasma— NPU02974 Nortriptyline; U—Oxandrolone; subst.c. = ? nmol/l substance concentration nanomole/liter Urine— M = 263,38 g/mol Oxazepam; NPU02923 arbitrary concentration(procedure) P—Nortriptyline; subst.c. = ? nmol/l M = 286,74 g/mol NPU02975 Urine— U—Oxazepam; arb.c.(proc.) = ? Nortriptyline; substance concentration Plasma— nanomole/liter Oxazepam; M = 263,38 g/mol substance concentration NPU04813 micromole/liter U—Nortriptyline; subst.c. = ? nmol/l M = 286,74 g/mol NPU04862 P—Oxazepam; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 534 H. OLESEN

Urine— Urine— Oxazepam; Oxprenolol; substance concentration substance concentration micromole/liter micromole/liter M = 286,72 g/mol M = 265,35 g/mol NPU04727 NPU03005 U—Oxazepam; subst.c. = ? µmol/l U—Oxprenolol; subst.c. = ? µmol/l

Patient— Urine— (administered); Oxycodone; substance rate(oral administration) arbitrary concentration(procedure) micromole/day M = 315,36 g/mol M = 252,27 g/mol NPU04591 NPU10247 U—Oxycodone; arb.c.(proc.) = ? Pt—Oxcarbazepine(administered); subst.rate(p.o.) = ? µmol/d Urine— Oxycodone; Plasma— substance concentration Oxcarbazepine; micromole/liter substance concentration M = 315,36 g/mol micromole/liter NPU04912 M = 252,27 g/mol U—Oxycodone; subst.c. = ? µmol/l NPU03902 P—Oxcarbazepine; subst.c. = ? µmol/l Urine— ; Urine— arbitrary concentration(procedure) Oxcarbazepine; M = 318,44 g/mol substance concentration NPU04564 micromole/liter U—Oxymesterone; arb.c.(proc.) = ? M = 252,27 g/mol NPU03989 Urine— U—Oxcarbazepine; subst.c. = ? µmol/l Oxymesterone; substance concentration Urine— nanomole/liter Oxedrine; M = 318,44 g/mol arbitrary concentration(procedure) NPU03017 M = 167,21 g/mol U—Oxymesterone; subst.c. = ? nmol/l Authority: BAN NPU04575 Urine— U—Oxedrine; arb.c.(proc.) = ? ; arbitrary concentration(procedure) Urine— M = 332,47 g/mol Oxedrine; NPU04730 substance concentration U—Oxymetholone; arb.c.(proc.) = ? mole/liter M = 167,21 g/mol Plasma— Other term(s): Oxymetholone; Authority: BAN substance concentration NPU02976 nanomole/liter U—Oxedrine; subst.c.= ? prefix ? mol/l M = 332,47 g/mol NPU04255 Urine— P—Oxymetholone; subst.c. = ? nmol/l Oxprenolol; arbitrary concentration(procedure) Urine— M = 265,35 g/mol Oxymetholone; NPU04620 substance concentration U—Oxprenolol; arb.c.(proc.) = ? nanomole/liter M = 332,47 g/mol NPU03020 U—Oxymetholone; subst.c. = ? nmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 535

Urine— Plasma— ; Paracetamol; arbitrary concentration(procedure) substance concentration M = 301,33 g/mol micromole/liter NPU04256 M = 151,16 g/mol U—Oxymorphone; arb.c.(proc.) = ? NPU03024 P—Paracetamol; subst.c. = ? µmol/l Plasma— Oxymorphone; Urine— substance concentration Paracetamol; mole/liter substance concentration M = 301,33 g/mol micromole/liter NPU04258 M = 151,16 g/mol P—Oxymorphone; subst.c.= ? prefix ? mol/l NPU04810 U—Paracetamol; subst.c. = ? µmol/l Urine— Oxymorphone; Plasma— substance concentration Paramethadione; mole/liter substance concentration M = 301,33 g/mol millimole/liter NPU04257 M = 157,17 g/mol U—Oxymorphone; subst.c.= ? prefix ? mol/l NPU10200 P—Paramethadione; subst.c. = ? mmol/l Urine— Oxytetracycline; Patient— arbitrary substance concentration(procedure) (administered); arbitrary unit/liter substance rate(oral administration) M = 460,44 g/mol micromole/day NPU08824 M = 329,37 g/mol U—Oxytetracycline; arb.subst.c.(proc.) = ? arb.unit/l NPU10249 Pt—Paroxetine(administered); subst.rate(p.o.) = ? Plasma— µmol/d Oxytetracycline; substance concentration Urine— mole/liter Paroxetine; M = 460,44 g/mol arbitrary concentration(procedure) NPU08823 M = 329,37 g/mol P—Oxytetracycline; subst.c.= ? prefix ? mol/l NPU09085 U—Paroxetine; arb.c.(proc.) = ? Urine— Oxytetracycline; Plasma— substance concentration Paroxetine; mole/liter substance concentration M = 460,44 g/mol nanomole/liter NPU08825 M = 329,37 g/mol U—Oxytetracycline; subst.c.= ? prefix ? mol/l NPU04863 P—Paroxetine; subst.c. = ? nmol/l Patient— Paracetamol(administered); Urine— substance rate(oral administration) Paroxetine; millimole/day substance concentration M = 151,16 g/mol nanomole/liter NPU10248 M = 329,37 g/mol Pt—Paracetamol(administered); subst.rate(p.o.) = ? NPU09084 mmol/d U—Paroxetine; subst.c. = ? nmol/l

Urine— Urine— Paracetamol; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 151,16 g/mol M = 176,16 g/mol NPU04596 NPU03031 U—Paracetamol; arb.c.(proc.) = ? U—Pemoline; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 536 H. OLESEN

Urine— Urine— Pemoline; ; substance concentration substance concentration micromole/liter micromole/liter M = 176,16 g/mol NPU17532 NPU03034 U—Penicillin; subst.c. = ? µmol/l U—Pemoline; subst.c. = ? µmol/l Urine— Urine— Pentazocine; Penbutolol; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 285,44 g/mol M = 285,43 g/mol NPU03035 NPU04621 U—Pentazocine; arb.c.(proc.) = ? U—Penbutolol; arb.c.(proc.) = ? Urine— Urine— Pentazocine; Penbutolol; substance concentration substance concentration micromole/liter micromole/liter M = 285,44 g/mol M = 291,43 g/mol NPU03038 NPU04512 U—Pentazocine; subst.c. = ? µmol/l U—Penbutolol; subst.c. = ? µmol/l Urine— Urine— Pentetrazol; Penicillin(specification); arbitrary concentration(procedure) substance concentration M = 138,17 g/mol micromole/liter NPU04598 NPU12942 U—Pentetrazol; arb.c.(proc.) = ? U—Penicillin(spec.); subst.c. = ? µmol/l Urine— Cerebrospinal fluid— Pentetrazol; Penicillin; substance concentration substance concentration micromole/liter micromole/liter M = 138,17 g/mol NPU12939 NPU03041 Csf—Penicillin; subst.c. = ? µmol/l U—Pentetrazol; subst.c. = ? µmol/l

Plasma— Urine— Penicillin; Pentobarbital; substance concentration arbitrary concentration(procedure) micromole/liter M = 226,3 g/mol NPU12941 NPU03042 P—Penicillin; subst.c. = ? µmol/l U—Pentobarbital; arb.c.(proc.) = ?

Secretion(specification)— Plasma— Penicillin; Pentobarbital; substance concentration substance concentration micromole/liter micromole/liter NPU12940 M = 226,3 g/mol Secr(spec.)—Penicillin; subst.c. = ? µmol/l NPU03954 P—Pentobarbital; subst.c. = ? µmol/l System(specification)— Penicillin; Urine— substance concentration Pentobarbital; micromole/liter substance concentration NPU17528 micromole/liter Syst(spec.)—Penicillin; subst.c. = ? µmol/l M = 226,3 g/mol NPU04733 U—Pentobarbital; subst.c. = ? µmol/l

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Plasma— Urine— Pentobarbital; Pethidine; substance concentration arbitrary concentration(procedure) nanomole/liter M = 247,34 g/mol NPU16394 Other term(s): Meperidin P—Pentobarbital; subst.c. = ? nmol/l NPU03049 U—Pethidine; arb.c.(proc.) = ? Urine— ; Urine— arbitrary concentration(procedure) Pethidine; M = 365,50 g/mol substance concentration NPU09056 micromole/liter U—Periciazine; arb.c.(proc.) = ? M = 247,34 g/mol Other term(s): Meperidin Plasma— NPU03052 Periciazine; U—Pethidine; subst.c. = ? µmol/l substance concentration mole/liter Urine— M = 365,50 g/mol Phenazocine; NPU09054 arbitrary concentration(procedure) P—Periciazine; subst.c.= ? prefix ? mol/l M = 321,44 g/mol NPU04599 Urine— U—Phenazocine; arb.c.(proc.) = ? Periciazine; substance concentration Urine— mole/liter Phenazocine; M = 365,50 g/mol substance concentration NPU09055 micromole/liter U—Periciazine; subst.c.= ? prefix ? mol/l M = 321,44 g/mol NPU03055 Patient— U—Phenazocine; subst.c. = ? µmol/l (administered); substance rate(oral administration) Urine— micromole/day ; M = 403,97 g/mol arbitrary substance concentration(procedure) NPU10250 arbitrary unit/liter Pt—Perphenazine(administered); subst.rate(p.o.) = M = 188,22 g/mol ? µmol/d Other term(s): Antipyrine NPU08808 Urine— U—Phenazone; arb.subst.c.(proc.) = ? arb.unit/l Perphenazine; arbitrary concentration(procedure) Plasma— M = 403,97 g/mol Phenazone; NPU03048 substance concentration U—Perphenazine; arb.c.(proc.) = ? mole/liter M = 188,22 g/mol Plasma— Other term(s): Antipyrine Perphenazine; NPU08806 substance concentration P—Phenazone; subst.c.= ? prefix ? mol/l nanomole/liter M = 403,97 g/mol Urine— NPU03047 Phenazone; P—Perphenazine; subst.c. = ? nmol/l substance concentration mole/liter Urine— M = 188,22 g/mol Perphenazine; Other term(s): Antipyrine substance concentration NPU08807 nanomole/liter U—Phenazone; subst.c.= ? prefix ? mol/l M = 403,97 g/mol NPU04259 U—Perphenazine; subst.c. = ? nmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 538 H. OLESEN

Urine— Plasma— ; Phenobarbital; arbitrary concentration(procedure) substance concentration M = 191,26 g/mol micromole/liter NPU04606 M = 232,24 g/mol U—Phendimetrazine; arb.c.(proc.) = ? NPU03062 P—Phenobarbital; subst.c. = ? µmol/l Urine— Phendimetrazine; Urine— substance concentration Phenobarbital; micromole/liter substance concentration M = 191,26 g/mol micromole/liter NPU03058 M = 232,24 g/mol U—Phendimetrazine; subst.c. = ? µmol/l NPU04738 U—Phenobarbital; subst.c. = ? µmol/l Urine— ; Plasma— arbitrary concentration(procedure) Phenobarbital; M = 121,18 g/mol substance concentration NPU04607 nanomole/liter U—Phenethylamine; arb.c.(proc.) = ? NPU16390 P—Phenobarbital; subst.c. = ? nmol/l Urine— Phenethylamine; Urine— substance concentration Phenolphthalein; micromole/liter arbitrary concentration(procedure) M = 121,18 g/mol M = 318,31 g/mol NPU04926 NPU03064 U—Phenethylamine; subst.c. = ? µmol/l U—Phenolphthalein; arb.c.(proc.) = ?

Urine— Plasma— ; Phenoxymethylpenicillin; arbitrary concentration(procedure) substance concentration M = 177,24 g/mol mole/liter NPU04608 M = 350,38 g/mol U—Phenmetrazine; arb.c.(proc.) = ? Other term(s): Penicillin V NPU08809 Urine— P—Phenoxymethylpenicillin; subst.c.= ? prefix ? Phenmetrazine; mol/l substance concentration micromole/liter Plasma— M = 177,24 g/mol Phenprocoumon; NPU03061 substance concentration U—Phenmetrazine; subst.c. = ? µmol/l mole/liter M = 280,31 g/mol Patient— NPU08810 Phenobarbital(administered); P—Phenprocoumon; subst.c.= ? prefix ? mol/l substance rate(oral administration) micromole/day Urine— M = 232,24 g/mol Phentermine; NPU10251 arbitrary concentration(procedure) Pt—Phenobarbital(administered); subst.rate(p.o.) = M = 149,23 g/mol ? µmol/d NPU03065 U—Phentermine; arb.c.(proc.) = ? Urine— Phenobarbital; Urine— arbitrary concentration(procedure) Phentermine; M = 232,24 g/mol substance concentration NPU03063 micromole/liter U—Phenobarbital; arb.c.(proc.) = ? M = 149,23 g/mol NPU03068 U—Phentermine; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 539

Urine— Plasma— ; (total); arbitrary concentration(procedure) substance concentration M = 167,17 g/mol micromole/liter NPU04609 M = 252,26 g/mol U—Phenylephrine; arb.c.(proc.) = ? NPU03085 P—Phenytoin(tot.); subst.c. = ? µmol/l Urine— Phenylephrine; Urine— substance concentration ; mole/liter arbitrary concentration(procedure) M = 167,17 g/mol M = 165,23 g/mol Other term(s): m-Synephrine NPU04617 NPU03081 U—Pholedrine; arb.c.(proc.) = ? U—Phenylephrine; subst.c.= ? prefix ? mol/l Urine— Urine— Pholedrine; Phenylpropanolamine; substance concentration arbitrary concentration(procedure) mole/liter M = 151,20 g/mol M = 165,23 g/mol Authority: BAN NPU03086 NPU04615 U—Pholedrine; subst.c.= ? prefix ? mol/l U—Phenylpropanolamine; arb.c.(proc.) = ? Plasma— Urine— ; Phenylpropanolamine; substance concentration substance concentration mole/liter micromole/liter M = 461,56 g/mol M = 151,20 g/mol NPU08811 Authority: BAN P—Pimozide; subst.c.= ? prefix ? mol/l NPU03084 U—Phenylpropanolamine; subst.c. = ? µmol/l Urine— Pindolol; Patient(Blood)— arbitrary concentration(procedure) Phenytoin elimination; M = 248,32 g/mol half-life(procedure) NPU04626 hour U—Pindolol; arb.c.(proc.) = ? NPU03810 Pt(B)—Phenytoin elimination; half-life(proc.) = ? h Urine— Pindolol; Patient— substance concentration Phenytoin(administered); micromole/liter substance rate(oral administration) M = 248,32 g/mol micromole/day NPU04527 M = 252,26 g/mol U—Pindolol; subst.c. = ? µmol/l NPU10252 Pt—Phenytoin(administered); subst.rate(p.o.) = ? Urine— µmol/d Piperacillin; arbitrary concentration(procedure) Plasma— M = 517,56 g/mol Phenytoin(free); NPU10211 substance concentration U—Piperacillin; arb.c.(proc.) = ? micromole/liter M = 252,26 g/mol Urine— NPU08971 ; P—Phenytoin(free); subst.c. = ? µmol/l arbitrary concentration(procedure) M = 267,36 g/mol NPU04618 U—Pipradrol; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 540 H. OLESEN

Urine— Urine— Pipradrol; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 383,41 g/mol M = 267,36 g/mol NPU04263 NPU03177 U—Prazosin; arb.c.(proc.) = ? U—Pipradrol; subst.c. = ? µmol/l Plasma— Urine— Prazosin; ; substance concentration substance concentration mole/liter micromole/liter M = 383,41 g/mol M = 362,41 g/mol NPU04265 NPU04619 P—Prazosin; subst.c.= ? prefix ? mol/l U—Piretanide; subst.c. = ? µmol/l Urine— Urine— Prazosin; ; substance concentration arbitrary concentration(procedure) mole/liter M = 331,35 g/mol M = 383,41 g/mol NPU04260 NPU04264 U—Piroxicam; arb.c.(proc.) = ? U—Prazosin; subst.c.= ? prefix ? mol/l

Plasma— Plasma— Piroxicam; ; substance concentration substance concentration mole/liter mole/liter M = 331,35 g/mol M = 360,44 g/mol NPU04262 NPU08812 P—Piroxicam; subst.c.= ? prefix ? mol/l P—Prednisolone; subst.c.= ? prefix ? mol/l

Urine— Plasma— Piroxicam; Prednisone; substance concentration substance concentration mole/liter mole/liter M = 331,35 g/mol M = 358,44 g/mol NPU04261 NPU08813 U—Piroxicam; subst.c.= ? prefix ? mol/l P—Prednisone; subst.c.= ? prefix ? mol/l

Urine— Plasma— Practolol; ; arbitrary concentration(procedure) substance concentration M = 266,34 g/mol nanomole/liter NPU03231 M = 318,50 g/mol U—Practolol; arb.c.(proc.) = ? Other term(s): Pregnanolone NPU04061 Urine— P—Pregnanolone; subst.c. = ? nmol/l Practolol; substance concentration Patient— micromole/liter (administered); M = 266,34 g/mol substance rate(oral administration) NPU04623 micromole/day U—Practolol; subst.c. = ? µmol/l M = 218,25 g/mol NPU10253 Urine— Pt—Primidone(administered); subst.rate(p.o.) = ? ; µmol/d arbitrary concentration(procedure) M = 288,41 g/mol Other term(s): ; DHEA NPU09103 U—Prasterone; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 541

Urine— Plasma— Primidone; +Acecainide; arbitrary concentration(procedure) substance concentration M = 218,25 g/mol micromole/liter NPU04838 Note: M (procainamide) = 235,3 g/mol U—Primidone; arb.c.(proc.) = ? NPU03956 P—Procainamide+Acecainide; subst.c. = ? µmol/l Plasma— Primidone; Urine— substance concentration ; micromole/liter arbitrary concentration(procedure) M = 218,25 g/mol M = 217,35 g/mol NPU03235 NPU04632 P—Primidone; subst.c. = ? µmol/l U—Prolintane; arb.c.(proc.) = ?

Urine— Urine— Primidone; Prolintane; substance concentration substance concentration micromole/liter micromole/liter M = 218,25 g/mol M = 217,35 g/mol NPU04839 NPU03261 U—Primidone; subst.c. = ? µmol/l U—Prolintane; subst.c. = ? µmol/l

Plasma— Urine— Primidone+Phenobarbital; Promazine; substance concentration arbitrary concentration(procedure) micromole/liter M = 284,41 g/mol Note: M (Primidone) = 218,25 g/mol; NPU03262 M (Phenobarbital) = 232,24 g/mol U—Promazine; arb.c.(proc.) = ? NPU09346 P—Primidone+Phenobarbital; subst.c. = ? µmol/l Urine— Promazine; Urine— substance concentration ; micromole/liter arbitrary concentration(procedure) M = 284,41 g/mol M = 285,36 g/mol NPU04817 NPU04630 U—Promazine; subst.c. = ? µmol/l U—Probenecid; arb.c.(proc.) = ? Urine— Urine— Promethazine; Probenecid; arbitrary concentration(procedure) substance concentration M = 284,41 g/mol micromole/liter NPU03263 M = 285,36 g/mol U—Promethazine; arb.c.(proc.) = ? NPU03240 U—Probenecid; subst.c. = ? µmol/l Urine— Promethazine; Urine— substance concentration Procainamide; mole/liter arbitrary concentration(procedure) M = 284,41 g/mol M = 235,33 g/mol NPU04819 NPU04631 U—Promethazine; subst.c.= ? prefix ? mol/l U—Procainamide; arb.c.(proc.) = ? Urine— Plasma— ; Procainamide; arbitrary concentration(procedure) substance concentration M = 341,45 g/mol micromole/liter NPU04266 M = 235,33 g/mol U—Propafenone; arb.c.(proc.) = ? NPU03241 P—Procainamide; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 542 H. OLESEN

Plasma— Urine— Propafenone; ; substance concentration substance concentration micromole/liter mole/liter M = 341,45 g/mol M = 230,31 g/mol NPU04268 NPU08926 P—Propafenone; subst.c. = ? µmol/l U—Propyphenazone; subst.c.= ? prefix ? mol/l

Urine— Urine— Propafenone; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 263,37 g/mol M = 341,45 g/mol NPU09087 NPU04267 U—Protriptyline; arb.c.(proc.) = ? U—Propafenone; subst.c. = ? µmol/l Plasma— Urine— Protriptyline; Propranolol; substance concentration arbitrary concentration(procedure) nanomole/liter M = 259,35 g/mol M = 263,37 g/mol NPU03266 NPU04867 U—Propranolol; arb.c.(proc.) = ? P—Protriptyline; subst.c. = ? nmol/l

Plasma— Urine— Propranolol; Protriptyline; substance concentration substance concentration micromole/liter nanomole/liter M = 259,35 g/mol M = 263,37 g/mol NPU04964 NPU09086 P—Propranolol; subst.c. = ? µmol/l U—Protriptyline; subst.c. = ? nmol/l

Urine— Plasma— Propranolol; Proxyphylline; substance concentration substance concentration micromole/liter micromole/liter M = 259,35 g/mol M = 238,24 g/mol NPU03269 NPU08814 U—Propranolol; subst.c. = ? µmol/l P—Proxyphylline; subst.c. = ? µmol/l

Urine— Urine— ; Pseudoephedrine; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 155,28 g/mol M = 165,23 g/mol NPU04633 NPU04634 U—Propylhexedrine; arb.c.(proc.) = ? U—Pseudoephedrine; arb.c.(proc.) = ?

Urine— Urine— Propylhexedrine; Pseudoephedrine; substance concentration substance concentration micromole/liter micromole/liter M = 155,28 g/mol M = 165,23 g/mol NPU03272 NPU03311 U—Propylhexedrine; subst.c. = ? µmol/l U—Pseudoephedrine; subst.c. = ? µmol/l

Urine— Plasma— Propyphenazone; Pyrazinamide; arbitrary concentration(procedure) substance concentration M = 230,31 g/mol micromole/liter NPU08925 M = 123,11 g/mol U—Propyphenazone; arb.c.(proc.) = ? NPU08815 P—Pyrazinamide; subst.c. = ? µmol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 Properties and units in clinical pharmacology and toxicology 543

Urine— Plasma— Pyrazinamide; Quinine; substance concentration substance concentration micromole/liter micromole/liter NPU16483 M = 324,41 g/mol U—Pyrazinamide; subst.c. = ? µmol/l Authority: BAN NPU03350 Urine— P—Quinine; subst.c. = ? µmol/l Pyrimethamine; arbitrary concentration(procedure) Plasma— M = 248,71 g/mol ; NPU04269 substance concentration U—Pyrimethamine; arb.c.(proc.) = ? micromole/liter M = 371,27 g/mol Plasma— NPU04119 Pyrimethamine; P—Remoxipride; subst.c. = ? µmol/l substance concentration mole/liter Urine— M = 248,71 g/mol Remoxipride; NPU04271 substance concentration P—Pyrimethamine; subst.c.= ? prefix ? mol/l micromole/liter M = 371,27 g/mol Urine— NPU04120 Pyrimethamine; U—Remoxipride; subst.c.= ? µmol/l substance concentration mole/liter Urine— M = 248,71 g/mol ; NPU04270 arbitrary concentration(procedure) U—Pyrimethamine; subst.c.= ? prefix ? mol/l M = 608,69 g/mol NPU04272 Urine— U—Reserpine; arb.c.(proc.) = ? ; arbitrary concentration(procedure) Plasma— M = 245,26 g/mol Reserpine; NPU04635 substance concentration U—Pyrovalerone; arb.c.(proc.) = ? mole/liter M = 608,69 g/mol Urine— NPU04274 Pyrovalerone; P—Reserpine; subst.c.= ? prefix ? mol/l substance concentration mole/liter Urine— M = 245,26 g/mol Reserpine; NPU03326 substance concentration U—Pyrovalerone; subst.c.= ? prefix ? mol/l mole/liter M = 608,69 g/mol Urine— NPU04273 Quinethazone; U—Reserpine; subst.c.= ? prefix ? mol/l arbitrary concentration(procedure) M = 289,76 g/mol Urine— NPU04636 Rhein; U—Quinethazone; arb.c.(proc.) = ? arbitrary concentration(procedure) M = 284,22 g/mol Plasma— NPU04820 ; U—Rhein; arb.c.(proc.) = ? substance concentration micromole/liter Urine— M = 360,5 g/mol Rhein; Other term(s): Chinidine substance concentration Authority: BAN mole/liter NPU03349 M = 284,22 g/mol P—Quinidine; subst.c. = ? µmol/l NPU04821 U—Rhein; subst.c.= ? prefix ? mol/l

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 544 H. OLESEN

Plasma— Urine— ; ; arbitrary concentration(procedure) arbitrary concentration(procedure) NPU12401 M = 239,31 g/mol P—Rifampicin; arb.c.(proc.) = ? NPU04637 U—Salbutamol; arb.c.(proc.) = ? Urine— Rifampicin; Urine— arbitrary concentration(procedure) Salicylate; M = 822,96 g/mol arbitrary concentration(procedure) NPU04275 Note: M (anion) = 137,12 g/mol U—Rifampicin; arb.c.(proc.) = ? NPU03384 U—Salicylate; arb.c.(proc.) = ? Plasma— Rifampicin; Urine— substance concentration Salicylate; micromole/liter substance concentration M = 822,96 g/mol mole/liter Other term(s): Rifampin Note: M (anion) = 137,12 g/mol NPU04277 NPU04811 P—Rifampicin; subst.c. = ? µmol/l U—Salicylate; subst.c.= ? prefix ? mol/l

Urine— Plasma— Rifampicin; Salicylate; substance concentration substance concentration micromole/liter millimole/liter M = 822,96 g/mol Note: M (anion) = 137,12 g/mol NPU04276 NPU03383 U—Rifampicin; subst.c. = ? µmol/l P—Salicylate; subst.c. = ? mmol/l

Urine— Urine— ; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 410,49 g/mol M = 415,57 g/mol NPU09047 NPU04639 U—Risperidone; arb.c.(proc.) = ? U—Salmeterol; arb.c.(proc.) = ?

Plasma— Plasma— Risperidone; ; substance concentration substance concentration nanomole/liter nanomole/liter M = 410,49 g/mol M = 306,23 g/mol NPU04868 NPU09364 P—Risperidone; subst.c. = ? nmol/l P—Sertraline; subst.c. = ? nmol/l

Urine— Patient— Risperidone; (administered); substance concentration substance rate(oral administration) nanomole/liter micromole/day M = 410,49 g/mol Other term(s): Zocor NPU09046 NPU10254 U—Risperidone; subst.c. = ? nmol/l Pt—Simvastatin(administered); subst.rate(p.o.) = ? µmol/d Plasma— Salbutamol; Urine— arbitrary concentration(procedure) Sotalol; M = 239,31 g/mol arbitrary concentration(procedure) NPU10263 M = 272,36 g/mol P—Salbutamol; arb.c.(proc.) = ? NPU08674 U—Sotalol; arb.c.(proc.) = ?

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Plasma— Urine— Sotalol; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 334,42 g/mol M = 272,36 g/mol NPU04642 NPU04628 U—Strychnine; arb.c.(proc.) = ? P—Sotalol; subst.c. = ? µmol/l Urine— Urine— Strychnine; Sotalol; substance concentration substance concentration micromole/liter micromole/liter M = 334,42 g/mol M = 272,36 g/mol NPU03497 NPU03442 U—Strychnine; subst.c. = ? µmol/l U—Sotalol; subst.c. = ? µmol/l Urine— Plasma— ; Spiramycin; arbitrary concentration(procedure) substance concentration M = 386,56 g/mol mole/liter NPU04278 NPU08816 U—Sufentanil; arb.c.(proc.) = ? P—Spiramycin; subst.c.= ? prefix ? mol/l Plasma— Plasma— Sufentanil; ; substance concentration substance concentration mole/liter micromole/liter M = 386,56 g/mol M = 416,59 g/mol NPU04280 NPU04640 P—Sufentanil; subst.c.= ? prefix ? mol/l P—Spironolactone; subst.c. = ? µmol/l Urine— Urine— Sufentanil; Spironolactone; substance concentration substance concentration mole/liter micromole/liter M = 386,56 g/mol M = 416,59 g/mol NPU04279 NPU03468 U—Sufentanil; subst.c.= ? prefix ? mol/l U—Spironolactone; subst.c. = ? µmol/l Plasma— Urine— Sulfadiazine; ; substance concentration arbitrary concentration(procedure) mole/liter M = 328,48 g/mol M = 250,28 g/mol NPU04641 NPU08817 U—Stanozolol; arb.c.(proc.) = ? P—Sulfadiazine; subst.c.= ? prefix ? mol/l

Urine— Plasma— Stanozolol; Sulfadimidine; substance concentration substance concentration nanomole/liter mole/liter M = 328,48 g/mol M = 278,33 g/mol NPU03471 Other term(s): Sulfamethazine U—Stanozolol; subst.c. = ? nmol/l NPU08819 P—Sulfadimidine; subst.c.= ? prefix ? mol/l Plasma— Streptomycin; Plasma— substance concentration Sulfamerazine; micromole/liter substance concentration M = 581,58 g/mol mole/liter NPU10239 M = 264,31 g/mol P—Streptomycin; subst.c. = ? µmol/l NPU08818 P—Sulfamerazine; subst.c.= ? prefix ? mol/l

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Plasma— Urine— Sulfamethoxazole; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 225,29 g/mol M = 253,28 g/mol NPU04883 NPU10210 U—Terbutaline; arb.c.(proc.) = ? P—Sulfamethoxazole; subst.c. = ? µmol/l Plasma— Urine— Terbutaline; ; substance concentration arbitrary concentration(procedure) mole/liter M = 341,43 g/mol M = 225,29 g/mol NPU09050 NPU04284 U—Sulpiride; arb.c.(proc.) = ? P—Terbutaline; subst.c.= ? prefix ? mol/l

Plasma— Urine— Sulpiride; Terbutaline; substance concentration substance concentration mole/liter mole/liter M = 341,43 g/mol M = 225,29 g/mol NPU09048 NPU04877 P—Sulpiride; subst.c.= ? prefix ? mol/l U—Terbutaline; subst.c.= ? prefix ? mol/l

Urine— Urine— Sulpiride; ; substance concentration arbitrary concentration(procedure) mole/liter M = 471,68 g/mol M = 341,43 g/mol NPU04285 NPU09049 U—Terfenadine; arb.c.(proc.) = ? U—Sulpiride; subst.c.= ? prefix ? mol/l Plasma— Plasma— Terfenadine; Sultiame; substance concentration substance concentration mole/liter micromole/liter M = 471,68 g/mol M = 290,36 g/mol NPU04287 NPU10196 P—Terfenadine; subst.c.= ? prefix ? mol/l P—Sultiame; subst.c. = ? µmol/l Urine— Urine— Terfenadine; ; substance concentration arbitrary concentration(procedure) mole/liter M = 300,73 g/mol M = 471,68 g/mol NPU04281 NPU04286 U—Temazepam; arb.c.(proc.) = ? U—Terfenadine; subst.c.= ? prefix ? mol/l

Urine— Urine— Temazepam; Tertatolol; substance concentration arbitrary concentration(procedure) micromole/liter M = 295,45 g/mol M = 300,73 g/mol Authority: IFCC/C-LDA; INN NPU04282 NPU14147 U—Temazepam; subst.c. = ? µmol/l U—Tertatolol; arb.c.(proc.) = ?

Plasma— Urine— Temazepam; Tertatolol; substance concentration substance concentration nanomole/liter micromole/liter M = 300,73 g/mol M = 295,45 g/mol NPU04283 NPU04643 P—Temazepam; subst.c. = ? nmol/l U—Tertatolol; subst.c. = ? µmol/l

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Urine— Plasma— ; ; substance concentration substance concentration nanomole/liter micromole/liter M = 288,41 g/mol M = 180,17 g/mol Authority: IUPAC-IUB 84 Authority: BAN NPU03548 NPU03554 U—Testosterone; subst.c. = ? nmol/l P—Theophylline; subst.c. = ? µmol/l

Urine— Urine— ; Thiamine; arbitrary substance concentration(procedure) arbitrary substance concentration(procedure) arbitrary unit/liter arbitrary unit/liter M = 444,44 g/mol M = 300,81 g/mol NPU08827 NPU08830 U—Tetracycline; arb.subst.c.(proc.) = ? arb.unit/l U—Thiamine; arb.subst.c.(proc.) = ? arb.unit/l

Plasma— Plasma— Tetracycline; Thiamine; substance concentration substance concentration mole/liter mole/liter M = 444,44 g/mol M = 300,81 g/mol NPU08826 NPU08829 P—Tetracycline; subst.c.= ? prefix ? mol/l P—Thiamine; subst.c.= ? prefix ? mol/l

Urine— Urine— Tetracycline; Thiamine; substance concentration substance concentration mole/liter mole/liter M = 444,44 g/mol M = 300,81 g/mol NPU08828 NPU08831 U—Tetracycline; subst.c.= ? prefix ? mol/l U—Thiamine; subst.c.= ? prefix ? mol/l

Urine— Urine— d-6- Thiopental; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 242,34 g/mol Note: Minor (< 1 %) active constituent in Marihuana NPU08677 (Hashish) U—Thiopental; arb.c.(proc.) = ? NPU09000 U—d-6-Tetrahydrocannabinol; arb.c.(proc.) = ? Plasma— Thiopental; Urine— substance concentration Tetrahydrocannabinol; micromole/liter arbitrary concentration(procedure) M = 242,34 g/mol Other term(s): ; Delta-1- NPU04830 Tetrahydrocannabinol; Delta-9-Tetrahydrocannabinol P—Thiopental; subst.c. = ? µmol/l Note: Only major active constituent in Marihuana (Hashish) Urine— NPU08997 Thiopental; U—Tetrahydrocannabinol; arb.c.(proc.) = ? substance concentration micromole/liter Urine— M = 242,34 g/mol Tetrahydrocannabinol; NPU04831 substance concentration U—Thiopental; subst.c. = ? µmol/l nanomole/liter Other term(s): Dronabinol; Delta-1- Urine— Tetrahydrocannabinol; Delta-9-Tetrahydrocannabinol Thioridazine; Note: Only major active constituent in Marihuana arbitrary concentration(procedure) (Hashish) M = 370,58 g/mol NPU08998 NPU04644 U—Tetrahydrocannabinol; subst.c. = ? nmol/l U—Thioridazine; arb.c.(proc.) = ?

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Plasma— Plasma— Thioridazine; ; substance concentration substance concentration micromole/liter micromole/liter M = 370,58 g/mol M = 443,63 g/mol NPU04115 NPU03788 P—Thioridazine; subst.c. = ? µmol/l P—Tiotixene; subst.c. = ? µmol/l

Urine— Urine— Thioridazine; Tiotixene; substance concentration substance concentration micromole/liter micromole/liter M = 370,58 g/mol M = 443,63 g/mol NPU03556 NPU03741 U—Thioridazine; subst.c. = ? µmol/l U—Tiotixene; subst.c. = ? µmol/l

Urine— Plasma— Thiotepa; Tobramycin; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 189,22 g/mol NPU12367 NPU04288 P—Tobramycin; arb.c.(proc.) = ? U—Thiotepa; arb.c.(proc.) = ? Cerebrospinal fluid— Plasma— Tobramycin; Thiotepa; substance concentration substance concentration micromole/liter mole/liter NPU12923 M = 189,22 g/mol Csf—Tobramycin; subst.c. = ? µmol/l NPU04290 P—Thiotepa; subst.c.= ? prefix ? mol/l Plasma— Tobramycin; Urine— substance concentration Thiotepa; micromole/liter substance concentration M = 467,52 g/mol mole/liter NPU03586 M = 189,22 g/mol P—Tobramycin; subst.c. = ? µmol/l NPU04289 U—Thiotepa; subst.c.= ? prefix ? mol/l Secretion(specification)— Tobramycin; Plasma— substance concentration ; micromole/liter substance concentration NPU12924 nanomole/liter Secr(spec.)—Tobramycin; subst.c. = ? µmol/l M = 375,56 g/mol NPU10232 Urine— P—Tiagabine; subst.c. = ? nmol/l Tobramycin; substance concentration Urine— micromole/liter Timolol; NPU12925 arbitrary concentration(procedure) U—Tobramycin; subst.c. = ? µmol/l M = 316,42 g/mol NPU04629 Plasma— U—Timolol; arb.c.(proc.) = ? Tocofersolan; substance concentration Urine— micromole/liter Timolol; M = 430,69 g/mol substance concentration NPU03587 micromole/liter P—Tocofersolan; subst.c. = ? µmol/l M = 316,42 g/mol NPU04548 U—Timolol; subst.c. = ? µmol/l

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Urine— Urine— Tocofersolan; Tranylcypromine; substance concentration arbitrary concentration(procedure) micromole/liter M = 133,19 g/mol M = 430,69 g/mol NPU04759 NPU03588 U—Tranylcypromine; arb.c.(proc.) = ? U—Tocofersolan; subst.c. = ? µmol/l Plasma— Plasma— Tranylcypromine; ; substance concentration substance concentration mole/liter mole/liter M = 133,19 g/mol M = 270,34 g/mol NPU04291 NPU08832 P—Tranylcypromine; subst.c.= ? prefix ? mol/l P—Tolbutamide; subst.c.= ? prefix ? mol/l Urine— Plasma— Tranylcypromine; ; substance concentration substance concentration mole/liter micromole/liter M = 133,19 g/mol M = 339,37 g/mol NPU03608 NPU09119 U—Tranylcypromine; subst.c.= ? prefix ? mol/l P—Topiramate; subst.c. = ? µmol/l Urine— Urine— ; Tramadol; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 270,38 g/mol M = 263,39 g/mol NPU04645 NPU04549 U—Trenbolone; arb.c.(proc.) = ? U—Tramadol; arb.c.(proc.) = ? Urine— Urine— Trenbolone; Tramadol; substance concentration substance concentration mole/liter micromole/liter M = 270,38 g/mol M = 263,39 g/mol NPU04909 NPU04551 U—Trenbolone; subst.c.= ? prefix ? mol/l U—Tramadol; subst.c. = ? µmol/l Urine— Urine— ; Tranquilizing drug; arbitrary concentration(procedure) arbitrary concentration(list; procedure) M = 253,26 g/mol NPU04829 NPU04646 U—Tranquilizing drug; arb.c.(list; proc.) U—Triamterene; arb.c.(proc.) = ? NPU01151 U—Alprazolam; arb.c.(proc.) = ? NPU01402 U—Bromazepam; arb.c.(proc.) = ? Urine— NPU01534 U—Chlordiazepoxide; arb.c.(proc.) = ? Triamterene; NPU04843 U—Clobazam; arb.c.(proc.) = ? substance concentration NPU01880 U—Diazepam; arb.c.(proc.) = ? micromole/liter NPU02062 U—Flunitrazepam; arb.c.(proc.) = ? M = 253,26 g/mol NPU02614 U—Lorazepam; arb.c.(proc.) = ? NPU03615 NPU02916 U—Nitrazepam; arb.c.(proc.) = ? U—Triamterene; subst.c. = ? µmol/l NPU02975 U—Oxazepam; arb.c.(proc.) = ? Urine— Urine— ; Tranquilizing drug; arbitrary concentration(procedure) taxon(procedure) M = 343,21 g/mol NPU04662 NPU03616 U—Tranquilizing drug; taxon(proc.) = ? U—Triazolam; arb.c.(proc.) = ?

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552 550 H. OLESEN

Urine— Urine— Triazolam; ; substance concentration arbitrary concentration(procedure) micromole/liter M = 290,32 g/mol M = 343,21 g/mol NPU10243 NPU01634 U—Trimethoprim; arb.c.(proc.) = ? U—Triazolam; subst.c. = ? µmol/l Plasma— Plasma— Trimethoprim; Triazolam; substance concentration substance concentration micromole/liter nanomole/liter M = 290,32 g/mol M = 343,21 g/mol NPU08834 NPU08833 P—Trimethoprim; subst.c. = ? µmol/l P—Triazolam; subst.c. = ? nmol/l Urine— Urine— ; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 294,42 g/mol M = 407,50 g/mol NPU09089 NPU04292 U—Trimipramine; arb.c.(proc.) = ? U—Trifluoperazine; arb.c.(proc.) = ? Plasma— Urine— Trimipramine; Trifluoperazine; substance concentration substance concentration nanomole/liter mole/liter M = 294,42 g/mol M = 407,50 g/mol NPU04869 NPU04293 P—Trimipramine; subst.c. = ? nmol/l U—Trifluoperazine; subst.c.= ? prefix ? mol/l Urine— Plasma— Trimipramine; Trifluoperazine; substance concentration substance concentration nanomole/liter nanomole/liter M = 294,42 g/mol M = 407,50 g/mol NPU09088 NPU04294 U—Trimipramine; subst.c. = ? nmol/l P—Trifluoperazine; subst.c. = ? nmol/l Patient— Urine— (administered); Trimeperidine; substance rate(oral administration) arbitrary concentration(procedure) micromole/day M = 275,38 g/mol Note: M (anion) = 143,21 g/mol NPU04647 NPU10256 U—Trimeperidine; arb.c.(proc.) = ? Pt—Valproate(administered); subst.rate(p.o.) = ? µmol/d Urine— Trimeperidine; Plasma— substance concentration Valproate; micromole/liter substance concentration M = 275,38 g/mol micromole/liter NPU03628 Note: M (anion) = 143,21 g/mol U—Trimeperidine; subst.c. = ? µmol/l NPU03735 P—Valproate; subst.c. = ? µmol/l Plasma— Trimethadione; Urine— substance concentration Valproate; micromole/liter substance concentration M = 143,14 g/mol micromole/liter NPU10234 Note: M (anion) = 143,21 g/mol P—Trimethadione; subst.c. = ? µmol/l NPU04649 U—Valproate; subst.c. = ? µmol/l

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Plasma— Urine— Vancomycin; ; arbitrary concentration(procedure) substance concentration NPU12368 mole/liter P—Vancomycin; arb.c.(proc.) = ? M = 277,41 g/mol NPU09091 Urine— U—Venlafaxine; subst.c.= ? prefix ? mol/l Vancomycin; arbitrary concentration(procedure) Plasma— M = 1449,27 g/mol Venlafaxine; NPU10240 substance concentration U—Vancomycin; arb.c.(proc.) = ? nanomole/liter M = 277,41 g/mol Cerebrospinal fluid— NPU09090 Vancomycin; P—Venlafaxine; subst.c. = ? nmol/l substance concentration micromole/liter Plasma— NPU12931 ; Csf—Vancomycin; subst.c. = ? µmol/l substance concentration nanomole/liter Plasma— M = 454,61 g/mol Vancomycin; NPU08835 substance concentration P—Verapamil; subst.c. = ? nmol/l micromole/liter M = 1449,27 g/mol Plasma— NPU08731 Vigabatrin; P—Vancomycin; subst.c. = ? µmol/l substance concentration micromole/liter Secretion(specification)— NPU08966 Vancomycin; P—Vigabatrin; subst.c. = ? µmol/l substance concentration micromole/liter Plasma— NPU12930 Warfarin; Secr(spec.)—Vancomycin; subst.c. = ? µmol/l substance concentration mole/liter System(specification)— M = 308,33 g/mol Vancomycin; NPU08836 substance concentration P—Warfarin; subst.c.= ? prefix ? mol/l micromole/liter NPU17529 Urine— Syst(spec.)—Vancomycin; subst.c. = ? µmol/l ; arbitrary concentration(procedure) Urine— M = 307,40 g/mol Vancomycin; NPU09068 substance concentration U—Zolpidem; arb.c.(proc.) = ? micromole/liter NPU12929 Plasma— U—Vancomycin; subst.c. = ? µmol/l Zolpidem; substance concentration Urine— mole/liter Venlafaxine; M = 307,40 g/mol arbitrary concentration(procedure) NPU09066 M = 277,41 g/mol P—Zolpidem; subst.c.= ? prefix ? mol/l NPU09092 U—Venlafaxine; arb.c.(proc.) = ? Urine— Zolpidem; substance concentration mole/liter M = 307,40 g/mol NPU09067 U—Zolpidem; subst.c.= ? prefix ? mol/l

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Urine— Urine— ; ; arbitrary concentration(procedure) arbitrary concentration(procedure) M = 388,81 g/mol M = 400,97 g/mol NPU09070 Other term(s): Clopenthixol U—Zopiclone; arb.c.(proc.) = ? NPU01619 U—Zuclopenthixol; arb.c.(proc.) = ? Plasma— Zopiclone; Plasma— substance concentration Zuclopenthixol; mole/liter substance concentration M = 388,81 g/mol nanomole/liter NPU08837 M = 400,97 g/mol P—Zopiclone; subst.c.= ? prefix ? mol/l Other term(s): Clopenthixol NPU03962 Urine— P—Zuclopenthixol; subst.c. = ? nmol/l Zopiclone; substance concentration Urine— mole/liter Zuclopenthixol; M = 388,81 g/mol substance concentration NPU09069 nanomole/liter U—Zopiclone; subst.c.= ? prefix ? mol/l M = 400,97 g/mol Other term(s): Clopenthixol Patient— NPU04840 Zuclopenthixol(administered); U—Zuclopenthixol; subst.c. = ? nmol/l substance rate(oral administration) micromole/day M = 400,97 g/mol NPU10255 Pt—Zuclopenthixol(administered); subst.rate(p.o.) = ? µmol/d

© 2000 IUPAC, Pure and Applied Chemistry 72, 479–552