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Polarized Light Therapy” Cikkek Kivonatai PubMed „polarized light therapy” cikkek kivonatai 1. Masui. 2009 Nov;58(11):1401-6. [Phototherapy for chronic pain treatment] [Article in Japanese] Ide Y. Department of Anesthesia, Toho University Sakura Medical Center Sakura 285-8741. Three types of machines are used in the field of phototherapy for chronic pain. One type is an instrument for low reactive level laser therapy (LLLT), one is an instrument for linear polarized infrared light irradiation (SUPER LIZER), and the last one is an instrument for Xenon light irradiation (beta EXCEL Xe10). The available machines for LLLT all project laser by semiconductor. The newest machine (MEDILASER SOFT PULSE10) has peak power of 10 W and mean power of 1 W. This machine is as safe as 1 W machine and is effective twice as deep as the 1 W machine. The irradiation by low reactive level laser induces hyperpolarization, decreased resistance of neuronal membrane, and increased intra-cellular ATP concentrations. The effects of low reactive level laser might be induced by the activation of ATP-dependent K channel. The significant analgesic effects of 1 W and 10 W LLLT were reported with double blind test. The significant analgesic effects of linear polarized near infrared light irradiation with double blind test were also reported. The effects of low reactive level laser upon the sympathetic nerve system were thought to result from its normalization of the overloaded sympathetic nerve system. PMID: 19928507 [PubMed - indexed for MEDLINE] 2. Photomed Laser Surg. 2009 Oct 26. [Epub ahead of print] Healing of Surgical Wounds Made with lambda970-nm Diode Laser Associated or Not with Laser Phototherapy (lambda655 nm) or Polarized Light (lambda400-2000 nm). Medeiros JL, Nicolau RA, Nicola EM, Dos Santos JN, Pinheiro AL. 1 Center of Biophotonics, School of Dentistry, Federal University of Bahia , Salvador, Bahia, Brazil . Abstract Objective: The aim of this study was to analyze the effect of two phototherapies, laser and polarized light, on diode laser (970lambda nm) wounds. Background Data: Lasers have been used in surgery, and some wavelengths may cause thermal damage to the tissue and affect healing. Several studies have shown that some wavelengths are effective in improving healing. Coherent and noncoherent light have been successfully used on the modulation of biological phenomena of several origins. Animals and Methods: Thirty-one Wistar rats were divided into 3 groups (GI to GIII). A 20-mm x 2-mm wound was created on the dorsum of each animal with a diode laser (Sirolaser, Sirona((R)), Bensheim, Germany). Group GI acted as control. On GII, laser light (lambda655 nm, 30 mW, phi approximately 3 mm, 12 J/cm(2)) was used and on GIII illumination with polarized light (lambda400-2000 nm, 40 mW, phi approximately 5.5 cm, 12 J/cm(2)) was used, every other day (GII) or daily (GIII) for 7 days. The animals were killed at 0, 7, and 14 days after surgery. Specimens were taken, routinely processed, stained and imunnomarked [HE (hematoxylin-eosin), sirius red, alpha-smooth muscle actin (SMA)], and underwent histological analysis. Results: GII showed better response at day 14 when re-epithelialization was in a more advanced stage. The number of myofibroblasts was significantly different over the healing time (7 to 14 days); this number was smaller than that observed on G1. On GIII at day 7, the number of myofibroblasts was significantly higher than for GII. At day 14, a more pronounced deposition of collagen matrix was also seen, and inflammation was discrete and more advanced for GIII. Conclusion: The results of the present study showed that the effect of the use of laser light was more evident at early stages of healing and that the use of polarized light improved the resolution of the inflammatory reaction, increased the deposition of collagen, increased the number of myofibroblasts, and quickened re-epithelialization during the experimental time. PMID: 19857050 [PubMed - as supplied by publisher] 3. BMC Oral Health. 2009 Oct 2;9:25. In vitro effect of fluoride oral hygiene tablets on artificial caries lesion formation and remineralization in human enamel. Gängler P, Kremniczky T, Arnold WH. Faculty of Dental Medicine, University of Witten/Herdecke, Witten, Germany. [email protected] BACKGROUND: Aim of this in-vitro-study was to assess the remineralization potential of a tooth cleaning tablet with different fluoride content. METHODS: Twenty three caries free impacted third molars were examined, enamel surfaces were wax coated leaving two 3 x 4 mm windows for exposure to demineralization/remineralization cycles. The teeth were randomly assigned to 4 groups of 5 control and 6 experimental teeth. Demineralization by standardised HEC-gel, pH 4.7 at 37 degrees C for 72 h, was alternated by rinsing in remineralization solution, pH 7.0 at 37 degrees C for 72 h, total challenge time 432 h. The negative control group N was treated during remineralization cycles with saline; positive control group P was treated with remineralization solution; experimental group D1 was exposed to remineralization solution containing Denttabs-tablets with 1450 ppm F; experimental group D2 was exposed to remineralization solution and Denttabs-tablets with 4350 ppm F. Each tooth was cut into serial sections and analyzed by polarized light microscopy for assessment of the different zones of white-spot lesions in 3 representative sections. Statistical analysis was based on the Mann-Whitney-Test. RESULTS: Both control groups N(-) and P(+) exhibited characteristic white-spot lesions. The remineralization and the demineralization inhibition of the lesions increased considerably from N<P < D1<D2. Denttabs-2 administration showed partial/total remineralization including lamination and/or disappearance of the body of the lesion. The different results of all 4 groups were statistically highly significant (p < 0.01) with both tests. CONCLUSION: Based on these results the novel Denttabs formulation represents a highly effective oral hygiene product and the remineralization is correlated to the fluoride content. PMCID: PMC2762957 PMID: 19799785 [PubMed - indexed for MEDLINE] 4. J Alzheimers Dis. 2009 Sep 11. [Epub ahead of print] Copper Abolishes the beta-Sheet Secondary Structure of Preformed Amyloid Fibrils of Amyloid-beta<formula>_{42}</formula> House E, Mold M, Collingwood J, Baldwin A, Goodwin S, Exley C. The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, UK. The observation of the co-deposition of metals and amyloid-beta<formula>_{42}</formula> (Abeta<formula>_{42}</formula>) in brain tissue in Alzheimer's disease prompted a myriad of investigations into the role played by metals in the precipitation of this peptide. Copper is bound by monomeric Abeta<formula>_{42}</formula> and upon precipitation of the copper-peptide complex thereby prevents Abeta<formula>_{42}</formula> from adopting a beta-sheet secondary structure. Copper is also bound by beta-sheet conformers of Abeta<formula>_{42}</formula>, and herein we have investigated how this interaction affects the conformation of the precipitated peptide. Copper significantly reduced the thioflavin T fluorescence of aged, fibrillar Abeta<formula>_{42}</formula> with, for example, a 20-fold excess of the metal resulting in a ca 90% reduction in thioflavin T fluorescence. Transmission electron microscopy showed that copper significantly reduced the quantities of amyloid fibrils while Congo red staining and polarized light demonstrated a copper-induced abolition of apple-green birefringence. Microscopy under cross-polarized light also revealed the first observation of spherulites of Abeta<formula>_{42}</formula>. The size and appearance of these amyloid structures were found to be very similar to spherulites identified in Alzheimer's disease tissue. The combined results of these complementary methods strongly suggested that copper abolished the beta-sheet secondary structure of pre-formed, aged amyloid fibrils of Abeta<formula>_{42}</formula>. Copper may protect against the presence of beta-sheets of Abeta<formula>_{42}</formula> in vivo, and its binding by fibrillar Abeta<formula>_{42}</formula> could have implications for Alzheimer's disease therapy. PMID: 19749401 [PubMed - as supplied by publisher] 5. Photomed Laser Surg. 2009 Oct;27(5):813-8. The effects of light-emitting diode irradiation at 610 nm and 710 nm on murine T-cell subset populations. Lim JH, Lee J, Choi J, Hong J, Jhun H, Han J, Kim S. Department of Rehabilitation Medicine, Konkuk University Medical Center, Seoul, South Korea. OBJECTIVE: The aim of this study was to investigate the effects of light-emitting diode (LED) irradiation (radiant power, 0.047 mW; irradiation area, 1.13 cm(2)) at 610 nm and 710 nm on T-lymphocyte subset populations and cytokine expression using an in vivo rat model. BACKGROUND DATA: The proliferation of CD4+ T lymphocytes was induced by polychromatic visible polarized light at the range of 540-780 nm in a previous study, but the specific target wavelength for this effect has not yet been identified. METHODS: Before and after 4 weeks of LED phototherapy, whole blood samples were collected from 610 nm, 710 nm, and control groups. The percentages of CD4+ and CD8+ T lymphocyte populations were determined by flow cytometry. The transcript levels of representative cytokines of CD4+ T-cell (interleukin [IL]-4, interferon [IFN]gamma) and proinflammatory cytokines (IL-1beta, IL-6) were assessed with the reverse transcriptase-polymerase chain reaction. RESULTS: The population of CD4+ T cells increased significantly in 710 nm group on day 28 (p < 0.05), but it did not increase in the 610 nm or control group. The population of CD8+ T cells did not show any significant change after irradiation in all groups. The mRNA expression of IL-4 increased in both the 610 nm and 710 nm groups compared to the control group, but IFNgamma was not detected in any group. The transcripts of IL-1beta and IL-6 were slightly induced in the 710 nm group.
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