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Neal Notes - Home
WEBINARS WHITEPAPERS SOLUTION CENTERS JOBS BOARD WHAT'S NEW EDUCATION NEWS MAGAZINES JOURNALS CONFERENCES SUBMISSIONS ABOUT HOME CLOUD BIG DATA MOBILE NETWORKING SECURITY SOFTWARE INSIGHTSINSIGHTS HOT TOPICS Neal Notes - Home Latest Posts Israeli Semiconductor Industry Continues to Thrive, but Some Clouds May Be on Horizon Neal Leavitt MAY 30, 2014 14:58 PM A- A A+ Back in 1974, Dov Frohman, one of Intel’s first employees and the inventor of EPROM, erasable programmable read only memory, decided to leave Silicon Valley and return to Israel, his adopted home since 1949. Frohman was charged with helping Intel establish a small chip design center in Haifa, which at the time, was Intel’s first outside the U.S. The rest, as the cliché goes, is history. In a little over a generation, the Israeli semiconductor industry has grown to now employ more than 20,000; annual revenues are about US $5 billion. Intel, for instance, now has about 9,900 employees in Israel and is planning to invest almost $6 billion in upgrading its Kiryat Gat fab facility. In fact, since 1974, Intel has invested about $10.8 billion in the Israeli semiconductor industry. “We’ve exported goods worth $35 billion most from our production centers in Kiryat Gat and Jerusalem,” said Intel VP and Intel Israel CEO Maxine Fassberg. Sol Gradman is editor of TapeOut, a publication covering the semiconductor industry, and also chairs ChipEx, the country’s largest annual semiconductor/microelectronics conference. Gradman said Israel’s semiconductor industry today comprises three types of companies – fabless, multinational design centers, and fabs. -
Beyond Darwin: Evolvability and the Generation of Novelty Marc Kirschner
Kirschner M BMC Biology 2013, 11:110 http://www.biomedcentral.com/1741-7007/11/110 INTERVIEW Open Access Beyond Darwin: evolvability and the generation of novelty Marc Kirschner Marc Kirschner graduated in biochemistry from North- western University, moving to Berkeley for his doctoral research and with positions at Berkeley, Oxford Univer- sity and Princeton before he took a professorship at Uni- versity of California San Francisco where with Andrew Murray he did seminal research on the control of the cell cycle in Xenopus egg extracts that led to the discov- ery of how cyclin drives the cell cycle, and with Tim Mitchison on the dynamic instability of microtubules. In 1993 he moved to Harvard where in 2003 he became the founding Chair of the HMS Department of Systems Biology and was named the John Franklin Enders Uni- versity Professor in 2009. The two books he wrote with John Gerhart, Cells, Embryos and Evolution (Blackwell, 1997) and The Plausibility of Life: Resolving Darwin’sDi- lemma (Yale University Press, 2005), reflect his deep and longstanding interest in how biological systems evolve. Here he gives his view of the evolution of evolvability and its profound importance for understanding and ap- plying biology. What is evolvability - how would you define it? Marc Kirschner In some sort of tautological way evolvability is simply the capacity of a system to evolve. But more than that, in a Darwinian sense it speaks to both the amount of effectively what I mean is that if you make random variation that is subject to selection, and the nature of changes in mechanical systems they inevitably either that variation. -
Award Recipients with Citations
IEEE JACK A. MORTON AWARD RECIPIENTS Beginning with the year 2000 presentation, the Jack A. Morton Award will be renamed the IEEE Andrew S. Grove Award. 1999 - CHARLES H. HENRY "For fundamental contributions to the Lucent Technologies, Bell Laboratories understanding of the optical properties of Murray Hill, NJ quantum wells and semiconductor lasers." 1998 - ISAMU AKASAKI “For contributions in the field of Meijo University group-III nitride materials and devices.” Nagoya, Japan and SHUJI NAKAMURA Nichia Chemical Industries, Ltd. Tokushima, Japan 1997 - CHENMING HU "For outstanding contributions to the physics and University of California modeling of MOS device reliability." Berkeley, CA 1996 - ROBERT W. DUTTON "For seminal contributions to semiconductor Stanford University process and device modeling." Stanford, CA 1995 - YOSHIO NISHI "For contributions to the basic understanding and Hewlett-Packard Company innovative development of MOS device Palo Alto, CA technology." 1994 - ROBERT E. KERWIN "For pioneering work and the basic patent on the AT&T self-aligned silicon-gate process, a key element Warren, NJ in fabrication of very large scale integrated and DONALD L. KLEIN circuits." IBM Corporation Hopewell Junction, NY and JOHN C. SARACE Rockwell International Anaheim, CA 1993 - TOSHIHISA TSUKADA "For contributions to the discovery and Hitachi, Ltd. development of Buried Heterostructure (BH) Tokyo, Japan semiconductor lasers." 1992 - TAKUO SUGANO "For contributions to Metal-Insulator- University of Tokyo Semiconductor Devices and Technology." Tokyo, Japan 1991 - TAK H. NING "For contributions to the development of HWA N. YU advanced bipolar and MOS devices." IBM Corporation Yorktown Height, NY 1 of 3 IEEE JACK A. MORTON AWARD RECIPIENTS Beginning with the year 2000 presentation, the Jack A. -
The Drosophila MCPH1-B Isoform Is a Substrate of the APC E3 Ubiquitin Ligase Complex
ß 2014. Published by The Company of Biologists Ltd | Biology Open (2014) 3, 669–676 doi:10.1242/bio.20148318 RESEARCH ARTICLE The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex Sarah G. Hainline`, Jamie L. Rickmyre`,*, Leif R. Neitzel, Laura A. Lee§ and Ethan Lee§ ABSTRACT and two primary co-activators, Cdc20 and Cdh1 (Kulkarni et al., 2013). Destruction of APC substrates is required in eukaryotes for The Anaphase-Promoting Complex (APC) is a multi-subunit E3 the initiation of anaphase and exit from mitosis. Cdc20 associates ubiquitin ligase that coordinates progression through the cell cycle by with the APC in early mitosis, leading to the destruction of temporally and spatially promoting the degradation of key proteins. proteins that control the onset of anaphase, whereas Cdh1 Many of these targeted proteins have been shown to play important promotes degradation of APC substrates that control late mitosis roles in regulating orderly progression through the cell cycle. Using and the following G1 phase. These co-activators provide APC a previously described Drosophila in vitro expression cloning substrate specificity by facilitating the recognition of specific approach, we screened for new substrates of the APC in Xenopus destruction motifs (e.g. degrons) such as the D-box (RxxLxxxxN) egg extract and identified Drosophila MCPH1 (dMCPH1), a protein or KEN box (Lys–Glu–Asn) (King et al., 1996; Min and Lindon, encoded by the homolog of a causative gene for autosomal recessive 2012; Pfleger and Kirschner, 2000). Mutations of these motifs primary microcephaly in humans. The dMCPH1-B splice form, but not block the recognition of the protein by the APC, preventing their the dMCPH1-C splice form, undergoes robust degradation in APC-mediated destruction. -
Deptbiochemistry00ruttrich.Pdf
'Berkeley University o'f California Regional Oral History Office UCSF Oral History Program The Bancroft Library Department of the History of Health Sciences University of California, Berkeley University of California, San Francisco The UCSF Oral History Program and The Program in the History of the Biological Sciences and Biotechnology William J. Rutter, Ph.D. THE DEPARTMENT OF BIOCHEMISTRY AND THE MOLECULAR APPROACH TO BIOMEDICINE AT THE UNIVERSITY OF CALIFORNIA, SAN FRANCISCO VOLUME I With an Introduction by Lloyd H. Smith, Jr., M.D. Interviews by Sally Smith Hughes, Ph.D. in 1992 Copyright O 1998 by the Regents of the University of California Since 1954 the Regional Oral History Office has been interviewing leading participants in or well-placed witnesses to major events in the development of Northern California, the West, and the Nation. Oral history is a method of collecting historical information through tape-recorded interviews between a narrator with firsthand knowledge of historically significant events and a well- informed interviewer, with the goal of preserving substantive additions to the historical record. The tape recording is transcribed, lightly edited for continuity and clarity, and reviewed by the interviewee. The corrected manuscript is indexed, bound with photographs and illustrative materials, and placed in The Bancroft Library at the University of California, Berkeley, and in other research collections for scholarly use. Because it is primary material, oral history is not intended to present the final, verified, or complete narrative of events. It is a spoken account, offered by the interviewee in response to questioning, and as such it is reflective, partisan, deeply involved, and irreplaceable. -
DEC SHOFAR Pages 1-10
THE A Publication of the Jewish Federation of Greater SH Chattanooga OF Volume 31 NumberAR 4 December 2018 Community Candle Lighting and Federation/ The State of the 2019 Annual Campaign Hadassah Lunch in December by Mike Spector, Campaign Chair Join us at the JCC for the annual We have reached the month of December. Our Chanukah candle lighting ceremony and Thanksgiving leftovers are long gone, and now we dinner, Sunday, December 2nd at 5:30 get ready for the eight nights of Chanukah, which pm. There will be oven-fried chicken, begin December 2nd. Students are wrapping up their potato latkes, green beans, and desserts. fall semester, and many people are looking toward Bring your own chanukiah or use one of end-of-the year vacations. ours. We will supply candles. But here at the Federation, it’s crunch time! This Cost is $12 per person or $30 for is when we reach out to donors we’ve not yet heard a family of four. Children age five to from, to encourage them to help us achieve our sixteen are $6; those under four get in annual goal. free. The per-person cost increases by $4 at the door, so rsvp early to The 2019 Annual Campaign is coming along quite [email protected], or by calling 493-0270. well. As of this printing we have just surpassed the $951,000 amount--so close On Tuesday, December 4th, join us again for a joint Federation/ to breaking $1,000,000 and beyond! Four-hundred seventy community members Hadassah Chanukah lunch. -
Plenary Speakers
FoCM95 Park City: Plenary speakers: WEEK 1 Marie-Francoise Roy, Universite de Rennes Shmuel Winograd, IBM Dima Y. Grigoriev, Pennsylvania State University Richard S. Varga, Kent State University Steve Smale, University of California, Berkeley John CannyUniversity of California, Berkeley Felipe Cucker, Universitat Pampeu Fabra, Spain Victor Pan, Herbert H. Lehman College, CUNY Michael Shub, IBM Roger Brockett, Harvard University WEEK 2 Henryk Wozniakowski, University of Warsaw David Donoho, University of California, Berkeley and Columbia University Yosef Yomdin, Weizmann Institute of Science, Israel Margaret H. Wright, AT&T Bell Laboratories N. Karmarker, AT&T Bell Laboratories Manuel Blum, University of California, Berkeley Roger Temam, Indiana University Arkadi Nemirovski, Israel Institute of Technology Hubertus Th.Jongen, Reinisch-Westf Tech Hochschule James M. Renegar, Cornell University WEEK 3 Herb Keller, California Institute of Technology Gene H. Golub, Stanford University Alexandre J. Chorin, University of California, Berkeley T. Y. Li, Michigan State University James Yorke, University of Maryland Lenore Blum, MSRI Eugene L. Allgower, Colorado State University Arieh Iserles, University of Cambridge, UK James W. Demmel, University of California, Berkeley W. Dahmen, Reinisch-Westf Tech Hochschule WEEK 4 Ronald A. DeVore, University of South Carolina, Columbia Ulrich Kulisch, University of Karlsruhe Victor A. V. Vassiliev, Institute for System Studies, Moscow Jacques Louis Lions, College de France Henryk Wozniakowski, University of -
Dov Frohman Looking for Unanticipated, Random Opportunities!
DOV FROHMAN LOOKING FOR UNANTICIPATED, RANDOM OPPORTUNITIES! INTERVIEW & STORY BY CHERYL PRUSS Many of you may remember retired Intel VP Dov Frohman from when he managed Intel Israel. His story, however, includes the horrors of the holocaust, working at Fairchild with Moore, Noyce and Grove, inventing the EPROM, teaching in Ghana, authoring a book on leadership and more. Here is just a glimpse of his fascinating life. THE EARLY YEARS rom the beginning, Dov Frohman has lived an eventful life. He F lost his parents to the holocaust, after they made sure he was safely hidden away by a Calvinist family in Holland. Later he spent time in orphanages for children whose parents had died in the war, before being adopted by relatives. Growing up in Tel Aviv, he served in the Israeli army prior to starting his advanced education. After graduating with a degree in Electrical Engineering from the Technion, Dov traveled to the United States to study for his masters and Ph.D. at the University of California, Berkeley. Berkeley in 1963, with it’s free speech movement and demonstrations, was an overwhelming experience and influence for a kid from Israel. In his book, Leadership the Hard Way, Dov summarized the impact this way: “What I learned at Berkeley is that unless you are prepared to see things differently and go against the current, you are unlikely to accomplish anything truly important. And to go against the current, you have to be something of an outsider, living on the edge, a member of a small but vibrant counterculture”. -
Foreign Innovators Generators of Open Innovation
American Journal of Innovative Research and Applied Sciences. ISSN 2429-5396 I www.american-jiras.com REVIEW ARTICLE FOREIGN INNOVATORS GENERATORS OF OPEN INNOVATION | llan Bijaoui *1 | *1. Graduate School of Business Management | Bar Ilan University | Ramat Gan | Israel | | Received | 25 November 2017 | | Accepted | 30 December 2018 | | Published 08 January 2019 | | ID Article | Bijaoui-ManuscriptRef.1-ajira251218 | Abstract Background: Immigrant innovators come to the host country with a different cultural background and have to adapt themselves to the local needs and behavior. Other foreign innovators cooperating with MNCs have also to find the way to be integrated and not to be classified as outsiders. Aims: We intend to prove that immigrant and other foreign innovators carry with them inflow of outside knowledge and change the outpourings of knowledge in host countries into discontinuous and disruptive open innovations. Our Method: Patents or diploma statistics cannot express the impact of foreign innovators on innovation processes. A case by case analysis is necessary in order to evaluate the impact of their researches. Results and Conclusion: The commitment of immigrant and other foreign innovators is greater and more diversified than inborn innovators due to the discontinuous and disruptive innovation processes they generate. Their contribution is in an extensive variety of key segments. A positive ecosystem around cooperation with foreign innovators could contribute to a more valuable development for home and host countries. Keywords: disruptive, discontinuous, immigration, foreigners, BoP, MNCs. 1. INTRODUCTION Lundvall (1992) [1] considers innovation to be an on-going procedure of getting the hang of, seeking and investigating, which result in innovative items and new or improved markets [1]. -
Interpretation: Hemichordates May Have No “Notochord”
iBioSeminars: Marc Kirschner, March 2008 The Origin of Vertebrates, Part 3 Part 3. How did the Chordate get its chord (notochord)? Marc Kirschner Dept. of Systems Biology Harvard Medical School Boston Massachusetts The Spemann experiment and the vertebrate specific development What about the notochord? Interpretation: Hemichordates • The crux of Bateson’s argument that hemichordates were essentially chordates. may have no “notochord”. • Virtually every marker of the vertebrate notochord is present in the hemichordate (chordin, noggin, admp, brachyury, hedgehog….) • Small problem, they are not in the hemichordate stromachord. The American Society for Cell Biology 1 iBioSeminars: Marc Kirschner, March 2008 The Origin of Vertebrates, Part 3 But does it have a Spemann Organizer? Though the organizer gives rise to the notochord in vertebrates, it is in fact also a complex signaling center. The hemichordate expresses genes of the chordate prechordal endo-mesoderm (otx, dmbx, ttf2, hex, gsc…), and at the appropriate A/P map position. ttf2/foxE2 dmbx Interpretation: as a signaling center, the hemichordate has an organizer otx The vertebrate organizer is a tripartite structure of signaling centers The American Society for Cell Biology 2 iBioSeminars: Marc Kirschner, March 2008 The Origin of Vertebrates, Part 3 But these organizer signaling centers are initially dispersed in hemichordates The vertebrate organizer is a composit of three distinct signaling centers in hemichordates • The vertebrate organizer is complex, since it conflates dorsal/ventral -
Mission Officielle En Israël Haïfa - Jérusalem - Tel Aviv
Mission officielle en Israël Haïfa - Jérusalem - Tel Aviv du 13 au 17 mars 2011 Haifa Jérusalem Tel Aviv La Mission en Israël Le programme du séjour La délégation marseillaise Marseille – Haïfa - Historique : 1958 : Le Jumelage Marseille – Haïfa - Les actions en cours et les perspectives 2011 : Renouvellement des accords de Coopération Marseille – Jérusalem -Historique -2011 : Renouvellement des accords de Coopération Marseille à l’heure des rendez-vous internationaux Chiffres Clefs Annexe : Accord de Coopération Haïfa Les liens qui unissent la France et plus particulièrement Marseille à l!Etat d!Israël n!ont cessé de se renforcer et de se développer au cours des années. En effet, la cité phocéenne et Haïfa sont jumelées depuis 1958 et ont signé des accords de coopération en 1995, réactualisés en 2000 et 2007. D!autre part Marseille et Jérusalem ont signé un premier accord de coopération en 2006. Marseille a été aussi une des premières villes de France a adhérer à la Fondation France - Israël dès sa création en 2006. C!est dans ce contexte que le Maire de Marseille, Jean-Claude GAUDIN, conduit une délégation de plus de 80 personnes dans trois villes de l!Etat d!Israël": Haïfa, Jérusalem et Tel Aviv. La délégation est composée d!élus, de chefs d!entreprises, de délégués du monde universitaire, scientifique et culturel, ainsi que des représentants des communautés juives de Marseille. Visite hautement symbolique, la dernière visite de l!édile remontant à 2004, cette mission est aussi "l'occasion de réactualiser les accords de coopération -
A Gramscian Analysis of the Hamula and the Relations Between the Israeli State and Palestinian Arab Citizens of Israel
A TALE OF TWO VILLAGES: A GRAMSCIAN ANALYSIS OF THE HAMULA AND THE RELATIONS BETWEEN THE ISRAELI STATE AND PALESTINIAN ARAB CITIZENS OF ISRAEL A THESIS SUBMITTED TO THE GRADUATE SCHOOL OF SOCIAL SCIENCES OF MIDDLE EAST TECHNICAL UNIVERSITY BY UMUT KOLDAŞ IN PARTIAL FULLFILMENT OF THE REQUIREEMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY IN THE DEPARTMENT OF INTERNATIONAL RELATIONS SEPTEMBER 2008 Approval of the Graduate School of Social Sciences Prof. Dr. Sencer Ayata Director I certify that this thesis satisfies all the requirements as a thesis for the degree of Doctor of Philosophy. Prof. Dr. Meliha B. Altunışık Head of Department This is to certify that we have read this thesis and that in our opinion it is fully adequate, in scope and quality, as a thesis for the degree of Doctor of Philosophy. Prof. Dr. Meliha B. Altunışık Supervisor Examining Committee Members Prof. Dr. İhsan Duran Dağı (METU, IR) Prof. Dr. Meliha B. Altunışık (METU, IR) Assist. Prof. Galip Yalman (METU, ADM) Assist. Prof. Özlem Tür (METU, IR) Assist Prof. İlker Aytürk (BILKENT, IR) I hereby declare that all information in this document has been obtained and presented in accordance with academic rules and ethical conduct. I also declare that, as required by these rules and conduct, I have fully cited and referenced all material and results that are not original to this work. Name, Last name : Signature : iii ABSTRACT A TALE OF TWO VILLAGES: A GRAMSCIAN ANALYSIS OF THE HAMULA AND THE RELATIONS BETWEEN THE ISRAELI STATE AND PALESTINIAN ARAB CITIZENS OF ISRAEL Koldaş, Umut Ph.D., Department of International Relations Supervisor: Prof.