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Rs. 500/- OFFICE OF THE DIRECTOR ALL INSTITUTE OF MEDICAL SCIENCES ANSARI NAGAR: NEW DELHI: 110 029 (SCHEDULE-‘A’)

S.NO. OF TENDER : ______FILE NO. : 3-S/Stores/17-18/RS/Advt.I/Gastro/AS/Sch.II

Name of the party in whose : ______favour the Tender form has ______been issued ______

The Director, All India Institute of Medical Sciences , Ansari Nagar.N.Delhi-29 (SEAL OF THE OFFICER)

Dear Sir,

1. I/We hereby submit our tender for the______.

2. I/WE now enclosing herewith the Bank Guarantee/D.D. No…………………… dated……………. for Rs.24,000/- (Rupees Forty Thousand Only) drawn in favour of the “SCHEME CELL, AIIMS” towards EMD/Bid Security. (TENDERS NOT ACCOMPANIED WITH EMD/BID SECURITY ALONGWITH THE TECHNO-COMMERCIAL BID SHALL BE SUMMARILY REJECTED).

3. I/We hereby agree to all the terms and conditions, stipulated by the AIIMS, in this connection including delivery, penalty etc. Quotations for each group are being submitted under separate covers, and sheets and shall be considered on their face value.

4. I/We have noted that overwritten entries shall be deleted unless duly cut & re-written and initialed.

5. Tenders are duly signed (No thumb impression should be affixed).

6. I/We undertake to sign the contract/agreement, if required, within 15 (Fifteen days) from the date of issue of the letter of acceptance, failing which our/my security money deposited may be forfeited and our/my name may be removed from the list of suppliers at the AIIMS New Delhi-29.

7. I/We have gone through all terms and conditions of the tender documents before submitting the same. NOTE: ALL TERMS & CONDITIONS SUCH AS TAXES ETC, HAS BEEN INDICATED IN THE QUOTATIONS FAILING WHICH IT WILL BE PRESUMED THAT THE RATES ARE INCLUSIVE OF ALL TAXES AND OTHER TERMS AND CONDITIONS ARE ALSO AS PER YOUR REQUIREMENTS.

Yours faithfully,

Signature of Tenders full address WITNESS______WITNESS______WITNESS______WITNESS______

CHECK LIST FOR TERMS AND CONDITIONS

Check list for Terms and Conditions (To be filled by the bidder and submitted alongwith the technical bid)

1) Certificate for being in business for more than 2 years______

2) Certificate for sole ownership/partnership ______

3) Statement of financial standing from bankers ______

4) Rates quoted included all taxes______

5) Rates quoted as per tender requirement ______

6) Affidavit that the firm has not been black listed in the past by any Organization/Hospital ______

7) Affidavit that the firm has no vigilance case/CBI case pending against the bidder______

8) Affidavit that the firm is not providing services at the lower rate quoted in the tender to any Govt. organization or any other Institute (Fall clause)______

9) Bid Security amount enclosed deposited ______

10) Details of Name of beneficiary, Account No. of the beneficiary, IFCS code to the bank/branch enclosed at Page No.______

11) Compliance Statement with relation to specification______

(NAME OF THE BIDDER) WITH SIGNATURE & SEAL ANNEXURE-I ALL INDIA INSTITUTE OF MEDICAL SCIENCES ANSARI NAGAR, NEW DELHI-29 (Research Section)

File No. T.No. 3-S/Stores/17-18/RS/Advt.I/Gastro/AS/Sch.II Tender Fee: Rs. 500.00 EMD : Rs. 24,000.00 Last Date of Submission : 25/05/2017 upto 12.30 p.m. Date of opening : 25/05/2017 at 3:00 p.m.

Subject: Small RNA Sequencing using Next Generation Sequencing (NGS)

Specification: -

T.No. 3-S/Stores/17-18/RS/Advt.I/Gastro/AS/Sch.II

Name of the Item: Small RNA Sequencing using Next Generation Sequencing (NGS)

Technical Specification for Small RNA sequencing using Next Generation Sequencing (NGS)

• Small RNA to be extracted from FFPE blocks. • Small RNA QC: miRNA QC should be done using both Bioanalyzer and Qubit Fluorometer and QC report should be provided. • Library Preparation: Small RNA libraries should be prepared using RNA library preparation kit. Library QC should be performed and QC report of libraries should be provided. • Sequencing: miRNA sequencing to be performed on Illumina Platform 75X2 bp Paired End Sequencing per sample. Output should be 35-40 million paired end reads per sample. • NGS Standard Analysis for Small RNA: Small RNA raw data QC should be performed. Further analysis to include: • Sequence/read quality, base composition and statistical analysis of sequencing. • Small RNA alignment and annotation (miRNA, siRNA) • Identification and Quantification of known and novel miRNA, detected & differentially expressed miRNA as up-regulated and down-regulated genes. • Significant biological analysis of Gene Ontology and pathways for identified target genes. • Raw data with quality and statistical analysis. • Pairwise comparison of total filtered small RNA reads • Deliverables: • RNA QC report, Library Preparation report, Sequence read report, Fast QC report for the sequencing output, Raw data should be provided in a hard disk, having read-me file with explanation and analysis report. • Number of samples: 60 samples

Terms & Conditions

• The quotations must be according to the two-bid system; technical specifications along with commercial terms and conditions in one envelop and financial quotation containing item wise price for the same mentioned in technical bid in another sealed envelope. • Both envelops should be placed in a bigger envelope which should be sealed and super-scribed. • The bidder should provide proof of in-house NGS facility and Bioinformatics analysis in India and allow scientists to visit for inspection at any stage of project process. • Sequencing and Bioinformatics analysis should be carried out by an experienced person (with publication on the same with his or her credit) and should have a PhD degree in the given subject. • Bioinformatics analysis and post analysis requirements, may change depending on the initial leads, bioinformatics support should be given until manuscript preparation and even to satisfy the reviewers comment (for 3 months after completion of the work and payment also). • Service provider should have standardized Lab and bioinformatics pipeline and should provide free training and support on Lab work and data analysis upon project completion at their facility and help in publication of research paper. • The turnaround time for the project should be less than 90 days. • The service provider should be certified as per ISO standards and any other certification/authorization related to the genomics platforms should be provided and will be considered during bid will be given a preference over others. • Service provider should have demonstrated expertise in Small RNA sequencing for ‘higher eukaryote' as evidenced by publication. Minimum 4-5 reference publication should be provided as a proof of technical capability for Small RNA sequencing project. • If there are discretions between technical bid and financial bid such bid will be disqualified and service provider would not be entertained in the future.

***** ANNEXURE - II

ALL INDIA INSTITUTE OF MEDICAL SCIENCES ANSARI NAGAR : NEW DELHI : 110 029 (SCHEDULE-‘B’)

Tender Ref. No. : T.No. 3-S/Stores/17-18/RS/Advt.I/Gastro/AS/Sch.II Subject : Small RNA Sequencing using Next Generation Sequencing (NGS) Date of Submission : 25/05/2017 upto 12.30PM Date of Opening : 25/05/2017 at 3:00 PM

1. Tender should be addressed to the Dean (RS), All India Institute of Medical Sciences, Ansari Nagar, New Delhi-29 and submitted to the Office of the Stores Officer, (Research Section), 1st Floor, Jawahar Lal Nehru Auditorium under sealed cover failing which the tender shall be rejected. Terms and conditions for supply should invariably be indicated otherwise would be taken on its face value. The rates may be quoted on separate sheets failing which the tender(s) will be rejected.

2. Mixed quotations will not be considered for acceptance.

3. IN CASE OF THE TENDER DOUMENTS DOWNLOADED FROM THE WEBSITE :- THE BIDDERS MAY DOWNLOAD THE TENDER DOCUMENTS DIRECTLY FROM THE WEBSITE AVAILABLE AT www.aiims.ac.in, www.aiims.edu. and www.tender.gov.in. IN SUCH CASE, THE BIDDERS ARE REQUIRED TO SUBMIT THE TENDER COST FEE OF Rs. 500/- (NON-REFUNDABLE) BY WAY OF SEPARATE DEMAND DRAFT DRAWN IN FAVOUR OF SCHEME CELL, AIIMS, AND THE SAME SHOULD ESSENTIALLY BE ENCLOSED ALONGWITH THE TECHNO COMMERCIAL BID. THE BIDDERS SHOULD SPECIFICALLY SUPERSCRIBE, “DOWNLOADED FROM THE WEBSITE” ON THE TOP LEFT CORNER OF THE OUTER ENVELOPE CONTAINING TECHNO COMMERCIAL BID & PRICE BID SEPARATELY. IN NO CASE, THE TENDER COST FEE SHOULD BE MIXED WITH EMD AMOUNT. THE TENDERS NOT FOLLOWING THE ABOVE PROCEDURE WILL BE SUMMARILLY REJECTED.

4. TENDER SHOULD BE SUBMITTED IN TWO BID SYSTEM CONTAINING TWO PARTS AS DETAILED BELOW: PART-I :- TECHNO-COMMERCIAL BID IN ONE SEALED COVER. PART-II:- PRICE BID/FINANCIAL BID IN ONE SEALED COVER.

BOTH THE SEALED ENVELOPES SHOULD THEN BE PUT IN ONE OUTERCOVER INDICATING THEREON:

i) Reference No. of the Tender ______ii) Tender regarding______iii) Due date for submission of the tender ______iv) Due date for opening of the tender______v) Name of the firm______

PLEASE NOTE THAT PRICES SHOULD NOT BE INDICATED IN THE TECHNO COMMERCIAL BID. THE PRE-QUALIFICATION DOCUMENTS INCLUDING E.M.D./BID SECURITY AS REQUIRED IN THE TENDER DOCUMENT SHOULD INVARIABLE BE ACCOMPANIED WITH THE TECHNO-COMMERCIAL BID.

NOTE:- TENDERS SUBMITTED WITHOUT FOLLOWING TWO BID SYSTEM PROCEDURE AS MENTIONED ABOVE WILL BE SUMMARILY REJECTED.

5. The tenderers should give rates, showing taxes, if any, and levies and insurance charges separately giving full breakup details. However, exercise Duty, if any, should be shown separately. Tender not confirming to these requirements shall be rejected and no correspondence will be entertained whatsoever.

6. THE TENDERERS ARE REQUIRED TO SUBMIT THE FOLLOWING INFORMATION INVARIABLE TO MAKE PAYMENT THROUNGH RGTS/NEFT. “The payment in pursuance of stores supplied/services rendered/work done will be made though RTGS/NEFT & charge incurred for affecting such electronic transfers will be borne by the vendors. The details of present charges for NEFT/RTGS are as under:- NEFT: Up to Rs. 1 lakh - Rs. 5/- Per transaction Rs. 1 lakh and above - Rs. 25/- Per transaction RTGS: Up to Rs. 5 lakh - Rs. 25/- Per transaction Rs. 5 Lakh and above - Rs. 50/- Per transaction To make payment trough above said mode, the vendor/supplier/contracts have to submit the following information invariably; i. Name of the Beneficiary ii. Account No. of the Beneficiary iii. IFCS Code of the Bank/Branch

Failing which their quotation is liable to be rejected

7. THIS TENDER DOCUMENT AND SUBSEQUENT RATE CONTRACT WITH THE APPROVED FIRM IS NON- TRANSFERABLE.

8. The bid document should be paged and a certificate may be provided on the covering letter indicating the number of pages submitted along with the bid.

9. The compliance report of tender specification should invariably be provided failing which the offer will be rejected.

10. The checklist may be furnished properly and page No. may be mentioned against each Serial Number.

11. The Tender forms be clearly filled in ink legibly or type written giving full address of the tenderers. The tenderers should quote in figures as well as in words the rates amount tendered by him/them Alterations/over-writings, unless legibly attested by the tenderer, shall disqualify the tenders. The tenders should be signed by the tenderer himself/themselves or his/their authorized agent on his/their behalf (Authorization may be enclosed, if applicable).

12. THE FORWARDING LETTER/UNDERTAKEN (SCHEDULE’A’) DULY SIGNED SHOULD INVARIABLY BE RETURNED ALONGWITH QUOTATIONS FURNISHED, FAILING WHICH THE TENDER SHALL BE REJECTED.

13. The tenderers should take care that the rates and amounts are written in such a way that interpolation is not possible, no blanks should be left which would otherwise, make the tender redundant.

14. The tender rates should be kept open/valid for a period of one year from the date the tenders are opened.

15. EACH TENDER SHOULD BE ACCOMPANIED WITH AN EMD/BID SECURITY AMOUNTING TO (as indicated in the tender Notice)/- BY WAY OF DEMAND DRAFT/ BANK GUARANTEE DRAWN IN FAVOUR OF “SCHEME CELL, AIIMS”, (PREFERABLY BANK GUARANTEE) FAILING WHICH THE TENDER SHALL NOT BE CONSIDERED FOR ACCEPTANCE AND WILL BE OUTRIGHTLY REJECTED. IN CASE OF BANK GUARANTEE, IT SHALL BE VALID FOR ONE YEAR FROM THE DATE OF OPENING AND THE SAME SHOULD BE FROM ANY SCHEDULED BANK (AS PER THE LIST ENCLOSED). CASH/CHEQUE/FDR IS NOT ACCEPTABLE AT ALL. THE EMD/BID SECURITY DEPOSITED AGAINST OTHER TENDERS CANNOT BE ADJUSTED OR CONSIDERED FOR THIS TENDER. NO INTEREST IS PAYABLE ON EMD/BID SECURITY.

16. If the services is not effected on due date, the Director, AIIMS, N. Delhi will have the right to impose penalty as under: A)First extension for one month or part thereof ______@2%. B)Second extension for an additional month or part therof.______@ 3%

17. In case of non supply of Services within the due date, the Director, AIIMS, New Delhi will have the right to impose penalty, as deemed fit, to resort to risk in full or part thereof at his/her discretion, his/her decision shall be final and binding.

18. Any other statutory levy imposed by the Govt. of India from time to time will be authorized extra on demand with adequate proof thereof will be paid extra.

19. Force majeure will be accepted on adequate proof thereof.

20. No payment shall be made for unacceptable services.

21. The Director, AIIMS, reserves the right to cancel/reject full or any part of the tender which do not fulfill the conditions stipulated in the tender.

22. Tenderers submitting tenders would be considered to have considered and accepted all the terms and conditions. No enquiries, verbal or written, shall be entertained in respect of acceptance or rejection of the tender.

23. TENDER MAY BE REJECTED IF THE COPY OF SERVICE TAX REGISTRATION IS NOT FURNISHED.

24. The quantity shown in the tender can be increased or decreased to any extent depending upon the actual requirement.

25. Any action on the part of the tender to influence anybody in the said Institute will be taken as an offence, he will not be allowed to participate in the tender enquiry and their offer will not be considered.

26. THE TENDERERS MUST QUOTE THE BEST SINGLE OPTION AS PER OUR REQUIREMENT. THE OFFERS SUBMITTED AS OPTION-A, OPTION-B OR C WILL NOT BE CONSIDERED AND SUCH OFFERS SUBMITTED IN THE FORM OF MULTIPLE OFFERS WILL BE SUMMERILY REJECTED.

27. The firm quoting for this tender is required to submit a certificate that they have satisfactory service arrangements and fully trained staff available.

28. The tenderer shall furnish a non-blacklisting certificate that the firm has not been blacklisted in the past by any government/Private institution. The tenderer/supplier has to give an affidavit on non-judicial stamp paper of Rs.10/- that there is no vigilance/CBI case pending against the firm/supplier and the firm has not been blacklisted in the past by any Govt. or Private Organization.

29. FALL CLAUSE If, at any time, during the said period, the approved vendor reduce the said prices of such services to any other person/organization/Institution at a price lower than the chargeable, he shall forthwith notify such reduction or sale to the Director, All India Institute of Medical Sciences and the price payable for the services after the date of coming into force of such reduction shall stand correspondingly reduced.

30. PAYMENT SHALL BE MADE WITHIN 30 DAYS FROM THE DATE OF SATISFACTORY REPORT/SERVICES PROVIDED THE APPROVED VENDOR.

31. Payment shall be made through Electronic Clearing System only and the charges shall be deducted from the bill.

ALL INDIA INSTITUTE OF MEDICAL SCIENCES RESEARCH SECTION NOTICE INVITING TENDER F. No. 01/Stores/RS/2017-18 (Adv.) On behalf of Dean (R), AIIMS, Ansari Nagar, New Delhi-110029, Stores Officer (RS) invites sealed tenders in two bid system (Technical bid and financial bid) from reputed, eligible and qualified authorized firms or manufacturers for supply of following Goods: S. File No. Name of the Item Tender Bid Security No Fee.(Rs) /EMD (Rs.) 1. 3-S/Stores/17-18/RS/Advt.I/ Purchase of Refrigerated Table Top 500/- 16,000/- Biophy/SD/Sch.I Centrifuge 2. 3-S/Stores/17-18/RS/Advt.I/ Small RNA Sequencing using Next 500/- 24,000/- Gastro/AS/Sch.II Generation Sequencing (NGS) 3. 3-S/Stores/17-18/RS/Advt.I/ Purchase of Epi-Fluorescence Microscope 500/- 18,000/- NS/PSC//Sch.III with Digital Cooled CCD Camera 4. 3-S/Stores/17-18/RS/Advt.I/ Purchase of Semi Motorised Microtome 500/- 14,000/- NS/PSC//Sch.IV Last date for sale of tender form: 24/05/2017 upto 04:30 pm Last date for submission: 25/05/2017 on or before upto 12:30 pm Date of Tender Opening (Technical Bids): On 25/05/2017 at 03:00 pm Contact Person: Store Officer, Research Section, First Floor, AIIMS, Ansari Nagar, New Delhi – 110 029 (1) Tender Enquiry documents containing detailed specifications along with terms and conditions can be had from the office of Stores Officer (RS) from 14.30 hrs. to 16.30 hrs on all working days (Monday to Friday) and 11.00 hrs to 12.30 hrs on Saturday. (2) Tender Enquiry Documents may be purchased on payment of non-refundable fee (as mentioned above in Indian currency or for an equivalent amount in foreign currency) by way of Demand Draft drawn in favour of ‘Scheme Cell, AIIMS, payable at New Delhi. (Postal Orders/Cash are not acceptable). (3) If requested, the Tender Enquiry Documents will be mailed by Registered Post/Speed Post to the domestic bidders and by international airmail to the foreign bidders, for which extra charges per set will be Rs.100/- for domestic post and Rs. 500/- or an equivalent amount in foreign currency for international airmail. The bidder is to add the applicable postage cost in the non-refundable fee mentioned in Para 3 above. (4) The bidders may also download the tender documents directly from the website available at www.aiims.ac.in, www.aiims.edu. and www.tenders.gov.in. In such case, the bidders are required to submit the tender cost fee of Rs.(as mentioned in NIT) (Non-refundable) by way of separate demand draft drawn in favour of ‘ Scheme Cell, AIIMS’ payable at New Delhi for each tender separately and the same should essentially be enclosed along with the techno commercial bid. The bidders should specifically superscribe, “Downloaded from the website” on the top left corner of the outer envelope containing techno commercial bid & price bid separately. In no case, the tender cost fee should be mixed with EMD amount. The tenders not following the above procedure will be summarily rejected. (5) It is the responsibility of the Bidders to ensure that their Bids, whether sent by post or by courier or by person, are dropped in the Tender Box of Stores Section (RS), “Research Section, 1st Floor at AIIMS, New Delhi-110 029” or received by the closing date and time stipulated above in the Para 2 for receipt of Bid, failing which the bid would be considered late and rejected. The bids dropped in the other section/departments/Centres of AIIMS, will not be considered for submission and such bids will be summarily rejected. (6) The bid security as mentioned above will have to be deposited through Bank Guarantee/Demand Draft drawn in favour of the “Scheme Cell, AIIMS” New Delhi along with the tender (Technical Bid). No interest is payable on Bid Security. (7) The Tender Enquiry document is not transferable. (8) In the event of any of the above mentioned dates being declared as a holiday / closed day for AIIMS, the tenders will be sold/received/opened on the next working day at the prescribed venue and time STORE OFFICER(RS) Please visit our website at www.aiims.edu, www.aiims.ac.in, & www.tenders.gov.in. for further details of this tender.

SECTION– XV

LIST OF SCHEDULED BANKS

A. Nationalized Banks 40. Ltd.,

41. Lakshmi Vikas Bank Ltd., 1. 42. Lord Krishna Bank Ltd., Kodangallur 2. 43. Ltd., Nainital 3. 44. Ltd., 4. 45. Punjab Co- operative Bank Ltd., 5. Bank of Maharastra Amritsar 6. 46. Ratnakar Bank Ltd., 7. of India 47. Sangli Bank Ltd., 8. 48. South Ltd., Trichur 9. 49. Tamilnadu mercantile Bank Ltd. 10. Indian Bank 50. United Westernank B Ltd., 11. 51. Vysya Bank Ltd., Bangalore 12.

13. Oriental Bank of Commerce D. Foreign Banks 14.

15. Punjab & Sindh Bank 52. ABN Amro Bank N.V.

16. 53. American Express Bank Ltd., 17. Union Bank 54. Bank of American National Trust

18. UCO Bank 55. Banque Nationale de Paris 19. 56. Bank of Tokyo Ltd.

20. 57. British Bank of the Middle East 58. bank

B. and its Associated 59. Citi Bank N.A.

Banks 60. ANZ Ltd.,

21. State Bank of India 61. The Sakura Bank Ltd.,

22. State Bank of Bikaner & Jaipur 62. Sonali Bank

23. State Bank of Hyderabhad 63. Deutscha bank A.G.

24. 64. Bank of Oman Ltd.,

25. 65. Abu Dhabi Commercial Bank Ltd.,

26. 66. Banque Indosuez

27. 67. Bank of Nova Scotia, Toronto

28. 68. Sociate General, Paris

69. Oman International Bank, S.A.G.O.

C. Private Sector Banks 70. Bank of Baharain and Kuwait.C.) (B.S

71. Hongkong & Shanghai Banking 29. Ltd., Madurai Corporation Ltd. 30. Ltd., Udaipur 72. Credit 31. Barelly Corporation Bank Ltd., Barelly 73. Barelays Bank P/c. 32. Banares State Bank Ltd.,nares Ba 74. Sanwa Bank, Tokyo 33. Ltd., Madras

34. Catholic Syrian Bank Ltd., Trichur E. Non-Scheduled Bank 35. Dhanalakshmi Bank Ltd., Alwaye

36. Jammu & Kashmir Bank Ltd., Srinagar 75. Kashi Nath Seth Bank Ltd.

37. Ltd., Alwaye 76. Bari Poab Bank Ltd.

38. Ltd., Mangalore 77. General Bank of Kurudwad Ltd. 39. Ltd.,

The list of banks is subject to change as and when Reserve of India Bank notifies any change in the list.