Troublesome Disguises Managing Challenging Disorders in Psychiatry
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Paranoid – Suspicious; Argumentative; Paranoid; Continually on The
Disorder Gathering 34, 36, 49 Answer Keys A N S W E R K E Y, Disorder Gathering 34 1. Avital Agoraphobia – 2. Ewelina Alcoholism – 3. Martyna Anorexia – 4. Clarissa Bipolar Personality Disorder –. 5. Lysette Bulimia – 6. Kev, Annabelle Co-Dependant Relationship – 7. Archer Cognitive Distortions / all-of-nothing thinking (Splitting) – 8. Josephine Cognitive Distortions / Mental Filter – 9. Mendel Cognitive Distortions / Disqualifying the Positive – 10. Melvira Cognitive Disorder / Labeling and Mislabeling – 11. Liat Cognitive Disorder / Personalization – 12. Noa Cognitive Disorder / Narcissistic Rage – 13. Regev Delusional Disorder – 14. Connor Dependant Relationship – 15. Moira Dissociative Amnesia / Psychogenic Amnesia – (*Jason Bourne character) 16. Eylam Dissociative Fugue / Psychogenic Fugue – 17. Amit Dissociative Identity Disorder / Multiple Personality Disorder – 18. Liam Echolalia – 19. Dax Factitous Disorder – 20. Lorna Neurotic Fear of the Future – 21. Ciaran Ganser Syndrome – 22. Jean-Pierre Korsakoff’s Syndrome – 23. Ivor Neurotic Paranoia – 24. Tucker Persecutory Delusions / Querulant Delusions – 25. Lewis Post-Traumatic Stress Disorder – 26. Abdul Proprioception – 27. Alisa Repressed Memories – 28. Kirk Schizophrenia – 29. Trevor Self-Victimization – 30. Jerome Shame-based Personality – 31. Aimee Stockholm Syndrome – 32. Delphine Taijin kyofusho (Japanese culture-specific syndrome) – 33. Lyndon Tourette’s Syndrome – 34. Adar Social phobias – A N S W E R K E Y, Disorder Gathering 36 Adjustment Disorder – BERKELEY Apotemnophilia -
The Development Concept of “Endogenous Psychoses” Helmut Beckmann, MD; Hermann Jakob, MD; Dieter Senitz, MD
Clinical research The development concept of “endogenous psychoses” Helmut Beckmann, MD; Hermann Jakob, MD; Dieter Senitz, MD Entorhinal region he entorhinal region is an outstanding, differ- T 1 entiated “association center” within the allocortex. It is intimately connected with the hippocampus by way of the perforant pathway. It thus forms, together with the hippocampus, a multineuronal regulatory circuit at the center of the limbic system. Signals arriving in the entorhinal cortex proceed to the hippocampus, pass Several structural deviances in the brain in “endogenous through several synapses, and return, in part, to the psychoses” have been described over the last decades. The entorhinal cortex. This regulatory circuit seems to be of enlargement of the lateral ventricles and the subtle struc- major importance for the storage of orientation and also tural deficits in temporobasal and orbital frontal struc- for memory.2 tures (hypofrontality) are reasonably well established in Studies in primates have shown that primary cortical the majority of schizophrenic patients. We examined the fields and all secondary cortical fields with visual, audi- cytoarchitecture of these important central structures, tory, and somatosensory functions have reciprocal con- namely the entorhinal region and the orbitofrontal cor- nections with the entorhinal cortex, either directly or by tex (Brodmann area 11), which have been under meticu- way of the perirhinal area.3-5 The multisensory areas in lous investigation in our laboratories over the last few caudal portions of the orbitofrontal region, and the ros- decades. In a new series of schizophrenic patients and nor- tral and ventral fields of the claustrocortex, project mal controls, we made serial cuts of the whole rostral mainly onto the rostral fields of the entorhinal area entorhinal cortex on both sides. -
Peter Riederer
Profiles (List of Publications) February 25, 2016 Peter Riederer 1 1992 (419) Frölich L, Riederer P (1992) Demenz vom Alzheimer-Typ: Biochemische Befunde und ätiologische Hypothesen. Therapiewoche 42 (9):500-505 (420) Riederer P, Lange KW, Kornhuber J, Danielczyk W (1992) Glutamatergic-Dopaminergic Balance in the Brain. Arzneim-Forsch/Drug Res 42 (I):265-268 (421) Gerlach M, Riederer P (1992) Biochemische Grundlagen der Psychosen. In: Der Medizinische Notfall VI. Proceedings, Interdisziplinäres Forum für Med. Fortbildung, Neuhofen/Ybbs, pp 65-71 (422) Riederer P, Laux G, Pöldinger W (1992) Neuro-Psychopharmaka, Bd. 1, SpringerVerlag WienNewYork (423) Berger W, Riederer P (1992) 10.2 Neurotransmitter-Regelkreise. Riederer P, Laux G, Pöldinger (eds) Neuro-Psychopharmaka, Bd. 1. Springer-Verlag WienNewYork, pp 225-271 (424) Müller WE, Riederer P, Kienzel E (1992) 9. Grundlegende Aspekte zur Neurotransmission. Riederer P, Laux G, Pöldinger (eds) Neuro-Psychopharmaka, Bd. 1. Springer-Verlag WienNewYork, pp 222-248 (425) Sofic E, Riederer P, Schmidt B, Fritze J, Kollegger H, Dierks T, Beckmann H (1992) Biogenic amines and metabolites in CSF from patients with HIV infection. Biogenic Amines 8 (5):293-298 (426) Riederer P, Lange KW (1992) Pathogenesis of Parkinson´s disease. Current Opinion in Neurology and Neurosurgery 5:295-300 (427) Gerlach M, Riederer P, Youdim MBH (1992) The molecular pharmacoloy of L-deprenyl. European Journal of Pharmacology - Molecular Pharmacology Section 226:97-108 (428) Hiemke C, Baumann P, Breyer-Pfaff U, Gold R, Klotz U, Müller-Oerlinghausen B, Rao M-L, Riederer P, Wetzel H, Wiedemann K (1992) Drug Monitoring in Psychiatric Patients: Which Approach is Useful to Improve Psychopharmacotherapy? Pharmacopsychiat 25:72-74 2 (429) Youdim MBH, Riederer P (1992) Iron in the Brain, and Parkinson´s Disease. -
FROM MELANCHOLIA to DEPRESSION a HISTORY of DIAGNOSIS and TREATMENT Thomas A
1 FROM MELANCHOLIA TO DEPRESSION A HISTORY OF DIAGNOSIS AND TREATMENT Thomas A. Ban International Network for the History of Neuropsychopharmacology 2014 2 From Melancholia to Depression A History of Diagnosis and Treatment1 TABLE OF CONTENTS Introduction 2 Diagnosis and classifications of melancholia and depression 7 From Galen to Robert Burton 7 From Boissier de Sauvages to Karl Kahlbaum 8 From Emil Kraepelin to Karl Leonhard 12 From Adolf Meyer to the DSM-IV 17 Treatment of melancholia and depression 20 From opium to chlorpromazine 21 Monoamine Oxidase Inhibitors 22 Monoamine Re-uptake Inhibitors 24 Antidepressants in clinical use 26 Clinical psychopharmacology of antidepressants 30 Composite Diagnostic Evaluation of Depressive Disorders 32 The CODE System 32 CODE –DD 33 Genetics, neuropsychopharmacology and CODE-DD 36 Conclusions 37 References 37 INTRODUCTION Descriptions of what we now call melancholia or depression can be found in many ancient documents including The Old Testament, The Book of Job, and Homer's Iliad, but there is virtually 1 The text of this E-Book was prepared in 2002 for a presentation in Mexico City. The manuscript was not updated. 3 no reliable information on the frequency of “melancholia” until the mid-20th century (Kaplan and Saddock 1988). Between 1938 and 1955 several reports indicated that the prevalence of depression in the general population was below 1%. Comparing these figures, as shown in table 1, with figures in the 1960s and ‘70s reveals that even the lowest figures in the psychopharmacological era (from the 1960s) are 7 to 10 times greater than the highest figures before the introduction of antidepressant drugs (Silverman 1968). -
Cotard's Syndrome: Two Case Reports and a Brief Review of Literature
Published online: 2019-09-26 Case Report Cotard’s syndrome: Two case reports and a brief review of literature Sandeep Grover, Jitender Aneja, Sonali Mahajan, Sannidhya Varma Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India ABSTRACT Cotard’s syndrome is a rare neuropsychiatric condition in which the patient denies existence of one’s own body to the extent of delusions of immortality. One of the consequences of Cotard’s syndrome is self‑starvation because of negation of existence of self. Although Cotard’s syndrome has been reported to be associated with various organic conditions and other forms of psychopathology, it is less often reported to be seen in patients with catatonia. In this report we present two cases of Cotard’s syndrome, both of whom had associated self‑starvation and nutritional deficiencies and one of whom had associated catatonia. Key words: Catatonia, Cotard’s syndrome, depression Introduction Case Report Cotard’s syndrome is a rare neuropsychiatric condition Case 1 characterized by anxious melancholia, delusions Mr. B, 65‑year‑old retired teacher who was pre‑morbidly of non‑existence concerning one’s own body to the well adjusted with no family history of mental illness, extent of delusions of immortality.[1] It has been most with personal history of smoking cigarettes in dependent commonly seen in patients with severe depression. pattern for last 30 years presented with an insidious However, now it is thought to be less common possibly onset mental illness of one and half years duration due to early institution of treatment in patients precipitated by psychosocial stressors. -
Collated Document Thomas A. Ban
1 THOMAS A. BAN: THE WERNICKE-KLEIST-LEONHARD TRADITION WITH SPECIAL REFERENCE TO MANIA, MELANCHOLIA AND MANIC-DEPRESSIVE PSYCHOSIS Collated Document Thomas A. Ban This document includes Thomas A. Ban’s five essays on the Wernicke-Kleist-Leonhard tradition with special reference to mania, melancholia and manic-depressive psychosis. It also includes Ernst Franzek’s comment and Ban’s reply to the last essay. The document is now open for a final comment to all INHN members. Thomas A. Ban August 6, 2015 Fundamentals of the Wernicke-Kleist-Leonhard tradition Thomas A. Ban October 22, 2015 Carl Wernicke’s classification of psychoses with special reference to mania, melancholia and manic-depressive psychosis Thomas A. Ban November 12, 2015 Karl Kleist and the deconstruction of Kraepelin’s diagnostic concept of manic- depressive psychosis Thomas A. Ban November 26, 2015 Karl Leonhard and the diagnostic re-evaluation of Emil Kraepelin’s diagnostic concept of manic- depressive psychosis Thomas A. Ban December 3, 2015 Psychopathology, Leonhard’s classification and the deconstruction of Kraepelin’s diagnostic concept of manic-depressive psychosis 2 Ernst Franzek February 18, 2016 Comment on Ban’s Psychopathology, Leonhard’s classification and the deconstruction of Kraepelin’s diagnostic concept of manic- depressive psychosis Thomas A. Ban August 6, 2015 Reply to Franzek’s comment Fundamentals of the Wernicke-Kleist-Leonhard Tradition Thomas A Ban In 1956, Fritz Freyhan, a German born American pioneer of neuropsychopharmacology focused attention on the heterogeneity in responsiveness to neuroleptics in patients with the diagnosis of schizophrenia and called for a pharmacological re-evaluation of Kraepelin’s diagnostic concepts (Bleuler 1911; Freyhan 1956; Kraepelin 1899). -
Monothematic Delusions: Towards a Two-Factor Account Davies, Martin, 1950- Coltheart, Max
Monothematic Delusions: Towards a Two-Factor Account Davies, Martin, 1950- Coltheart, Max. Langdon, Robyn. Breen, Nora. Philosophy, Psychiatry, & Psychology, Volume 8, Number 2/3, June/September 2001, pp. 133-158 (Article) Published by The Johns Hopkins University Press DOI: 10.1353/ppp.2001.0007 For additional information about this article http://muse.jhu.edu/journals/ppp/summary/v008/8.2davies.html Access Provided by Australian National University at 08/06/11 11:33PM GMT DAVIES, COLTHEART, LANGDON, AND BREEN / Monothematic Delusions I 133 Monothematic Delusions: Towards a Two-Factor Account Martin Davies, Max Coltheart, Robyn Langdon, and Nora Breen ABSTRACT: We provide a battery of examples of delu- There is more than one idea here, and the sions against which theoretical accounts can be tested. definition offered by the American Psychiatric Then we identify neuropsychological anomalies that Association’s Diagnostic and Statistical Manual could produce the unusual experiences that may lead, of Mental Disorders (DSM) seems to be based on in turn, to the delusions in our battery. However, we argue against Maher’s view that delusions are false something similar to the second part of the OED beliefs that arise as normal responses to anomalous entry: experiences. We propose, instead, that a second factor Delusion: A false belief based on incorrect inference is required to account for the transition from unusual about external reality that is firmly sustained despite experience to delusional belief. The second factor in what almost everyone else believes and despite what the etiology of delusions can be described superficial- constitutes incontrovertible and obvious proof or evi- ly as a loss of the ability to reject a candidate for belief dence to the contrary (American Psychiatric Associa- on the grounds of its implausibility and its inconsis- tion 1994, 765). -
Bipolar Disorders 100 Years After Manic-Depressive Insanity
Bipolar Disorders 100 years after manic-depressive insanity Edited by Andreas Marneros Martin-Luther-University Halle-Wittenberg, Halle, Germany and Jules Angst University Zürich, Zürich, Switzerland KLUWER ACADEMIC PUBLISHERS NEW YORK, BOSTON, DORDRECHT, LONDON, MOSCOW eBook ISBN: 0-306-47521-9 Print ISBN: 0-7923-6588-7 ©2002 Kluwer Academic Publishers New York, Boston, Dordrecht, London, Moscow Print ©2000 Kluwer Academic Publishers Dordrecht All rights reserved No part of this eBook may be reproduced or transmitted in any form or by any means, electronic, mechanical, recording, or otherwise, without written consent from the Publisher Created in the United States of America Visit Kluwer Online at: http://kluweronline.com and Kluwer's eBookstore at: http://ebooks.kluweronline.com Contents List of contributors ix Acknowledgements xiii Preface xv 1 Bipolar disorders: roots and evolution Andreas Marneros and Jules Angst 1 2 The soft bipolar spectrum: footnotes to Kraepelin on the interface of hypomania, temperament and depression Hagop S. Akiskal and Olavo Pinto 37 3 The mixed bipolar disorders Susan L. McElroy, Marlene P. Freeman and Hagop S. Akiskal 63 4 Rapid-cycling bipolar disorder Joseph R. Calabrese, Daniel J. Rapport, Robert L. Findling, Melvin D. Shelton and Susan E. Kimmel 89 5 Bipolar schizoaffective disorders Andreas Marneros, Arno Deister and Anke Rohde 111 6 Bipolar disorders during pregnancy, post partum and in menopause Anke Rohde and Andreas Marneros 127 7 Adolescent-onset bipolar illness Stan Kutcher 139 8 Bipolar disorder in old age Kenneth I. Shulman and Nathan Herrmann 153 9 Temperament and personality types in bipolar patients: a historical review Jules Angst 175 viii Contents 10 Interactional styles in bipolar disorder Christoph Mundt, Klaus T. -
Patient with Major Endogenous Depressive Episode with Suicide Attempt
Original Article International Journal of Research - GRANTHAALAYAH ISSN (Online): 2350-0530 May 2021 9(5), 137–144 ISSN (Print): 2394-3629 PATIENT WITH MAJOR ENDOGENOUS DEPRESSIVE EPISODE WITH SUICIDE ATTEMPT 1 1 1 2 3 Mariana Andrut, a Voicu , Adriana Mavlea , Ilinca Vlaicu , Florin Mititelu and Simona Trifu 1Faculty of Psychology and Educational Science, University of Bucharest, Romania 2Alex Obregia” Clinical Hospital for Psychiatry, Bucharest, Romania 3”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania ABSTRACT Motivation: Suicide is a major psychiatric emergency, men being more inclined to successful suicide, not to attempts and to approach it by abrupt and aggressive means. Objectives: To present a male patient who developed a major depressive episode, in which the reactive component had a signiicant contribution in return for endogeny. The suicide attempt quickly escalated changes in thymic function over several days. Results: The patient corresponds to the age at which major depressive dis- order begins. There remains a clinical discussion between a genuine suicide Received 28 April 2021 attempt, carried out with a plan, internal turmoil, rumination or a parasuicide, Accepted 18 May 2021 in which the person in question needed a change in the ield of consciousness Published 31 May 2021 to try to throw himself in front of the subway. Note the high internal tension, Corresponding Author the absence of the search for alternative solutions, the narcissistic wound, the Simona Trifu, simona.trifu@umfcd .ro endo-psychic vulnerability, the elements of correctness such as structural men- tal rigidity. DOI 10.29121/ granthaalayah.v9.i5.2021.3925 Conclusions: Early responsiveness to medication emphasizes the endoge- Funding: This research received nous potential and the potential of vulnerability, after the approach through no speciic grant from any funding a combination of antidepressants and antipsychotics, the latter developing a agency in the public, commercial, clearer perspective on reality and decisions. -
Normal Laboratory Values/Adult Patients
Normal Laboratory Values/Adult Patients Clinical Chemistry Tests Lipid Panel Alanine aminotransferase 13–48 U/L Cholesterol, total 160–240 mg/dL (ALT, SGPT) HDL cholesterol >40 mg/dL Albumin 3.6–5.2 g/dL LDL cholesterol <130 mg/dL Alkaline phosphatase (ALP) 35–120 U/L Triglycerides 55–200 mg/dL Amylase, serum 44–128 U/L Aspartate aminotransferase 15–41 U/L (AST, SGOT) Bilirubin, conjugated 0–0.2 mg/dL Thyroid Function Tests Bilirubin, total 0.2–1.2 mg/dL Thyroid stimulating hormone (TSH) 2–11 μU/mL Calcium 8.5–10.5 mg/dL Thyroxine, free (FT4) 0.8–2.4 ng/dL Carbon dioxide (CO2), total 23–30 mEq/L Thyroxine, total (T ) 4.0–12.0 μg/dL Chloride 98–109 mEq/L 4 Triiodothyronine (T )70–200 ng/dL Creatine kinase (CK, CPK) 40–260 U/L 3 Triiodothyronine (T ) resin uptake 25–38% Creatinine 0.7–1.2 mg/dL 3 (T3RU) Gamma glutamyltransferase 5–40 U/L (GGT) Glucose, fasting 65–110 mg/dL Hemoglobin A1C 5.0–7.0% of total Hb Blood Gases Iron, serum 50–170 μg/dL Iron-binding capacity, total 270–390 μg/dL Arterial Venous (TIBC) Base excess À3.0 to À5.0 to Lactate, serum (venous) 5.0–20.0 mg/dL +3.0 mEq/L +5.0 mEq/L Lactate dehydrogenase (LDH) 110–260 U/L Bicarbonate 18–25 mEq/L 18–25 mEq/L Lipase 10–140 U/L (HCO3) – – Magnesium 1.5–2.5 mg/dL pO2 80 95 mm Hg 30 48 mm Hg – – Potassium 3.5–5.1 mEq/L O2 saturation 95 98 % 60 85 % – – Prostate-specific antigen 0–4 ng/mL pCO2 34 45 mm Hg 35 52 mm Hg – – Protein, total 6.1–7.9 g/dL Total CO2 23 30 mEq/L 24 31 mEq/L – – Sodium 136–147 mEq/L pH 7.35 7.45 7.32 7.42 Troponin I <2.5 ng/mL Troponin T <0.2 ng/mL Urea nitrogen 6.0–20.0 mg/dL Hematology and Coagulation Tests Uric acid 2.6–7.2 mg/dL White blood cell (WBC) 4.4–11.0 K/mm3 count Hemoglobin 12.2–15.0 g/dL (continued) # Springer International Publishing Switzerland 2017 1811 P.M. -
Cotard's Syndrome
MIND & BRAIN, THE JOURNAL OF PSYCHIATRY REVIEW ARTICLE Cotard’s Syndrome Hans Debruyne1,2,3, Michael Portzky1, Kathelijne Peremans1 and Kurt Audenaert1 Affiliations: 1Department of Psychiatry, University Hospital Ghent, Ghent, Belgium; 2PC Dr. Guislain, Psychiatric Hospital, Ghent, Belgium and 3Department of Psychiatry, Zorgsaam/RGC, Terneuzen, The Netherlands ABSTRACT Cotard’s syndrome is characterized by nihilistic delusions focused on the individual’s body including loss of body parts, being dead, or not existing at all. The syndrome as such is neither mentioned in DSM-IV-TR nor in ICD-10. There is growing unanimity that Cotard’s syndrome with its typical nihilistic delusions externalizes an underlying disorder. Despite the fact that Cotard’s syndrome is not a diagnostic entity in our current classification systems, recognition of the syndrome and a specific approach toward the patient is mandatory. This paper overviews the historical aspects, clinical characteristics, classification, epidemiology, and etiological issues and includes recent views on pathogenesis and neuroimaging. A short overview of treatment options will be discussed. Keywords: Cotard’s syndrome, nihilistic delusion, misidentification syndrome, review Correspondence: Hans Debruyne, P.C. Dr. Guislain Psychiatric Hospital Ghent, Fr. Ferrerlaan 88A, 9000 Ghent, Belgium. Tel: 32 9 216 3311; Fax: 32 9 2163312; e-mail: [email protected] INTRODUCTION: HISTORICAL ASPECTS AND of the syndrome. They described a nongeneralized de´lire de CLASSIFICATION negation, associated with paralysis, alcoholic psychosis, dementia, and the ‘‘real’’ Cotard’s syndrome, only found in Cotard’s syndrome is named after Jules Cotard (1840Á1889), anxious melancholia and chronic hypochondria.6 Later, in a French neurologist who described this condition for the 1968, Saavedra proposed a classification into three types: first time in 1880, in a case report of a 43-year-old woman. -
1. Missionary Journal, “Chinese Character” This Article Was
1. Missionary Journal, “Chinese Character” This article was published in a Protestant missionary journal, based in Canton, that operated from 1832 until 1851. Its readership included both the foreigners living in Canton and home religious communities in Britain and the United States. It is worthwhile noting that the title of the article places the author in the position of knowledgeable observer, thereby rendering his comments both “factual” and honest. The author maintains a sympathetic attitude towards Chinese women, citing their beauty and charm, yet paints them as victims of insensitive males and an oppressive culture, presuming an invisible sorrow shared by all women in China. Confucianism is named as the primary offender, and Christian conversion the sole savior. One may presume that this portrayal of delicate Chinese women as victims of brutish Confucianism helped to excite enthusiasm for the missionary cause in China both at home and abroad. Source: Lay, G. Tradescant. “Remarks on Chinese Character and Customs.” Chinese Repository 12 (1843): 139-142. No apology can or ought to be made in the behalf of the unfeeling practice of spoiling the feet of the female. It had its origin solely in pride, which after the familiar adage, is said to feel no pain. It is deemed, however, such an essential among the elements of feminine beauty, that nothing save the sublimer considerations of Christianity will ever wean them from the infatuation. The more reduced this useful member is, the more graceful and becoming it is thought to be. When gentlemen are reciting the unparalleled charms of Súchau ladies they seldom forget to mention the extreme smallness of the foot, as that which renders them complete, and lays the topstone upon all the rest of their personal accomplishments.