Normal Laboratory Values/Adult Patients

Clinical Chemistry Tests Lipid Panel

Alanine aminotransferase 13–48 U/L Cholesterol, total 160–240 mg/dL (ALT, SGPT) HDL cholesterol >40 mg/dL Albumin 3.6–5.2 g/dL LDL cholesterol <130 mg/dL Alkaline phosphatase (ALP) 35–120 U/L Triglycerides 55–200 mg/dL Amylase, serum 44–128 U/L Aspartate aminotransferase 15–41 U/L (AST, SGOT) Bilirubin, conjugated 0–0.2 mg/dL Thyroid Function Tests Bilirubin, total 0.2–1.2 mg/dL Thyroid stimulating hormone (TSH) 2–11 μU/mL Calcium 8.5–10.5 mg/dL Thyroxine, free (FT4) 0.8–2.4 ng/dL Carbon dioxide (CO2), total 23–30 mEq/L Thyroxine, total (T ) 4.0–12.0 μg/dL Chloride 98–109 mEq/L 4 Triiodothyronine (T )70–200 ng/dL Creatine kinase (CK, CPK) 40–260 U/L 3 Triiodothyronine (T ) resin uptake 25–38% Creatinine 0.7–1.2 mg/dL 3 (T3RU) Gamma glutamyltransferase 5–40 U/L (GGT) Glucose, fasting 65–110 mg/dL

Hemoglobin A1C 5.0–7.0% of total Hb Blood Gases Iron, serum 50–170 μg/dL Iron-binding capacity, total 270–390 μg/dL Arterial Venous (TIBC) Base excess À3.0 to À5.0 to Lactate, serum (venous) 5.0–20.0 mg/dL +3.0 mEq/L +5.0 mEq/L Lactate dehydrogenase (LDH) 110–260 U/L Bicarbonate 18–25 mEq/L 18–25 mEq/L Lipase 10–140 U/L (HCO3) – – Magnesium 1.5–2.5 mg/dL pO2 80 95 mm Hg 30 48 mm Hg – – Potassium 3.5–5.1 mEq/L O2 saturation 95 98 % 60 85 % – – Prostate-specific antigen 0–4 ng/mL pCO2 34 45 mm Hg 35 52 mm Hg – – Protein, total 6.1–7.9 g/dL Total CO2 23 30 mEq/L 24 31 mEq/L – – Sodium 136–147 mEq/L pH 7.35 7.45 7.32 7.42 Troponin I <2.5 ng/mL Troponin T <0.2 ng/mL Urea nitrogen 6.0–20.0 mg/dL Hematology and Coagulation Tests Uric acid 2.6–7.2 mg/dL White blood cell (WBC) 4.4–11.0 K/mm3 count Hemoglobin 12.2–15.0 g/dL (continued)

# Springer International Publishing Switzerland 2017 1811 P.M. Paulman et al. (eds.), Family Medicine, DOI 10.1007/978-3-319-04414-9 1812 Normal Laboratory Values/Adult Patients

Hematocrit 37.0–54.0 % Eosinophils 0–5% Red blood cell (RBC) count 3.80–5.20 million/mm3 Basophils 0–2% Mean corpuscular volume 85.0–95.0 μm3 Sedimentation rate (MCV) Adult male 15 mm/hr Mean corpuscular 26.0–34.0 pg/cell Adult female 20 mm/hr hemoglobin (MCH) Coagulation tests – MCH concentration 32.6 36.0 g/dL Fibrinogen 200–400 mg/dL (MCHC) Partial thromboplastin time 60–85 seconds – Red cell distribution width 11.5 15.0 % (PTT) (RDW) Activated PTT 25–35 seconds Platelet count 150.0–420.0 K/mm3 Prothrombin time (PT) 11–14 seconds Reticulocyte count 0.5–1.5 % of RBCs Note: The reference intervals shown are for adults and may WBC differential vary according to technique or laboratory, or as new – Neutrophils 38 70 % methods are introduced. Always consult the reference Lymphocytes 16–49 % range for your own laboratory. Monocytes 2–9% (continued) Index

A respiratory acidosis, 1267–1268 ABCDE rules, 1605 respiratory alkalosis, 1266–1267 ABCX family crisis model, 390 AC joint arthritis, 1474–1475 ABCX model, 391 Acne, 1570–1572 Abdominal aortic aneurysms (AAA), 89 fulminans, 1571 Abdominal pain, 1160 inversa, 1573–1574 Abdominal pathology, patient evaluation ACOG, 158 history, 1212–1213 Acquired immunodeficiency syndrome (AIDS), 563, 870 imaging, 1214–1215 Acquired renal cystic disease, 1289 laboratory testing, 1214 Acrodermatitis chronica atrophicans, 573 physical examination, 1213–1214 ACTH stimulation, 1708 Abdominal radiation, 1203 Actinic keratosis, 1603–1604 Abdominal trauma Actinic lentigo, 1606 background, 1217–1218 Action to Control Cardiovascular Risk Reduction diagnosis, 1218 (ACCORD) trial, 1652, 1656, 1657 management, 1218–1219 Activated charcoal, 616–617 Abetalipoproteinemia, 1639 Active listening, 713 Ablation therapy, 990, 994 Active suicidal ideations, 441 Abnormal uterine bleeding, 1371, 1375–1379 Activities of daily living (ADL), 306 Abnormalities in vital signs, 460–461 Acupuncture, 420, 767, 1392, 1466, 1780–1781 Absence epilepsy, 825 Acute abdomen, 1212 Absent breast tissue, 1418 Acute abdominal pain, 1212 Absolute reticulocyte count, 1723 Acute abnormal uterine bleeding, 1371 Absolute risk reduction, 52 Acute angle-closure glaucoma, 923 Abstinence, 541 Acute back pain, 682–683 Abuse, 388 Acute bacterial prostatitis, 1299 Acalculous cholecystitis, 1223 Acute bacterial rhinosinusitis (ABRS), 242 Acamprosate, 767 Acute bilirubin encephalopathy, 223 Accommodation loss. See Presbyopia Acute bronchiolitis, 244 Accountable Care Organization (ACO), 61, 1788 Acute bronchitis, 513–514 Accreditation Council for Graduate Medical Education, Acute cervical strain, 1468–1469 1768 Acute closed angle glaucoma, 899–900 Accutane, 1572 Acute coronary syndrome (ACS), 974, 976–978, 1066 ACE inhibitors, 968–969, 1073, 1289 Acute cystitis, 154 Acetabular labral tear (ALT), 1498 Acute gastroenteritis, 250–251 Acetaminophen (APAP), 618–621, 1519 Acute headaches, 881 Achilles tendon, 1505 Acute heart failure syndrome (AHFS), 1025–1026 Achilles tendon rupture, 692, 1508–1509 Acute interstitial nephritis, 503, 1284 Achilles tendonopathy, 692 Acute kidney injury (AKI) Acholic stools, 1163 definition, 1283 Acid base disorders postrenal, 1284–1285 metabolic acidosis, 1264–1266 prerenal, 1283–1284 metabolic alkalosis, 1267 prevention and treatment, 1285–1286 mixed acid–base disturbance, 1268–1270 risk factors, 1285

# Springer International Publishing Switzerland 2017 1813 P.M. Paulman et al. (eds.), Family Medicine, DOI 10.1007/978-3-319-04414-9 1814 Index

Acute lacerations Adenoviral conjunctivitis, 894 anesthesia, 635–638 Adenoviruses, 892, 1144, 1235 antibiotics, 646–647 ADHD. See Attention deficit/hyperactivity disorder coding and billing, 647–648 (ADHD) indications/contraindications to primary closure, ADHD-predominately hyperactive/impulsive, 256 634–635 fidgety, 256 principles and techniques, wound closure, 639–643 interrupts, 256 skin anatomy and wound healing, 634 restless, 256 suture characteristics, 639, 640 talkative, 256 wound care and follow up, 647 Adhesive capsulitis, 1477 wound closure, 634 Adhesive strips, 645, 646 wound preparation and assessment, 638–639 Adipose tissue, 701 Acute limb ischemia, 1052 Adiposity, 701 Acute mesenteric ischemia, 1236 Adjunctive therapies, 521–522 Acute orchitis, 1323 Adjunctive treatment, 524 Acute otitis media (AOM), 244–246 Adjustment disorder, 416 causes, 929 Adjuvant therapy, 704 complications, 931 Adnexal torsion, 1439 diagnosis, 929–930 Adolescence stage epidemiology, 929 driving, 20 prevention, 931 puberty, 19, 20 treatment, 930–931 sexual identity and development, 20 Acute pain, 788 substance use, 19–20 Acute pancreatitis, 1158, 1463 Adolescent acne, 1571 Acute pelvic pain Adolescents, 101–103, 722 definition, 1436 anticipatory guidance, 300 diagnosis, 1437 confidentiality, 295 gastrointestinal disorders, 1439 emotional maturity, 296 history, 1436 immunizations, 299 imaging modalities, 1437 physical examination, 299 infectious gynecologic causes of, 1437–1438 psychosocial health issues, 297 laboratory analysis, 1436–1437 sexual development, 299 noninfectious gynecologic causes of, 1438–1439 Adrenarche, 1706 physical exam, 1436 Adult cardiovascular life support (ACLS) program, 840 pregnancy risk, 1437 Adult hearing loss, 948–949 urinary tract disorders, 1439–1440 conductive hearing loss, 948 Acute pericarditis, 1053–1054 evaluation and diagnosis, 948–949 Acute poststreptococcal glomerulonephritis, 524 prevention, 949 Acute proliferative glomerulonephritis, 1276 sensorineural hearing loss, 948 Acute respiratory distress syndrome (ARDS), treatment, 949 1112–1114 Adult Protective Services (APS), 351 Acute rheumatic fever, 524 Adult vaccination, 83 Acute rhinosinusitis, 520 Advance and cut technique, 662–663 Acute risk, 444 Advance directive, 345 Acute SMA occlusion, 1236 Advanced adenomas, 1201 Acute somatization Advanced directives, 802–803 social support, 453 Advanced lipid tests, 1641 stress-related symptoms, 453 Advanced maternal age, 161–162 Acute stress disorder, 412, 416 Adverse Events Reporting System (VAERS), 75 Acute urinary retention, 1298 Advisory Committee on Immunization Practices (ACIP), Acute urticaria, 1577 74, 84 Acyclovir (Zovirax), 156, 540, 877 Aerobic exercise, 1550, 1655 Adaptive immune responses, 508 Affective deficits, 559 Addison disease, 1710 African-American men, 1103 Adenocarcinoma, 1106 Age-adjusted D-dimer, 1045 Adenohypophysis, 1702 Agency for Healthcare Research and Quality (AHRQ), Adenoma detection rate (ADR), 1205 74, 1762 Adenomas, 1200 Aging, 722 Adenomyosis, 1443 Agitation, 344 Index 1815

Agoraphobia, 413, 414 5α-reductase inhibitors, 1298 AIDS. See Acquired immunodeficiency syndrome Alpha thalassemia trait, 1726 (AIDS) Alprazolam, 857 Air bronchograms, 221 Altemeier procedure, 1191 Air pollution, 1104 Altered sleep, 476 Akinesia, 852 Alveolitis, 1120 Alanine aminotransferase, 1167 Alzheimer’s disease, 853, 1641 Albendazole, 252, 568, 570, 1143 Amantadine (Symmetrel), 854–856 Alcohol, 72, 78, 83, 87, 162, 1158, 1160–1163 Amaurosis fugax, 921 Alcohol abuse, 40 Amblyopia, 924 Alcohol consumption, 1202 Ambulatory blood pressure monitoring, 971 Alcohol septal ablation, 1062 Amenorrhea, 142, 460, 1213, 1371, 1383 Alcohol use disorder (AUD), 414, 755 American Academy of Family Physicians (AAFP), diagnosis, 756–757 1428, 1793 prevalence, 756 American Academy of Pediatrics (AAP), 1314 screening, 756 American Association of Clinical Endocrinologists treatment, 757–759 (AACE), 1653 Alcohol Use Disorders Identification Test (AUDIT), 756 American Board of Family Medicine, 41 Alcohol withdrawal syndrome (AWS) The American Board of Family Practice (ABFP), 5 DT management, 763 American Board of Medical Specialties (ABMS), 1768 inpatient treatment, 761 American Board of Pathology (ABPath), 1768 monitoring withdrawal outpatient, 762 American Board of Preventive Medicine (ABPM), 1768 outpatient treatment, 760 American College of Chest Physicians, 1107 Alcoholic Hepatitis, 1174 American College of Obstetrics and Gynecologists laboratory findings associated with, 1175 (ACOG), 1314 Alcoholic neuropathy, 869–870 American Heart Association (AHA), 839 Alcoholics anonymous (AA), 758 American Medical Association (AMA), 588 Alcoholism, 870, 1731 American Medical Informatics Association Aldosterone, 1712 (AMIA), 1761 Aldosterone receptor antagonists, 1023 American Stroke Association (ASA), 839 Aldosteronism, 966 American Urological Association’s (AUA), 1314 Alfuzosin, 1298 American with Disabilities Act Amendment Act Algorithm, 703, 1108 (ADAAA), 584 Alkaline phosphatase, 1556 American’s with Disabilities Act (ADA), 584–585 Allergen sensitization testing, 483 Aminocaproic acid, 847 Allergens, 1080 Aminosalicylate, 1155 irritants, 1362–1363 Amiodarone, 858 Allergic conjunctivitis, 895–896 Amnioinfusion, 186 Allergic contact cheilitis, 1575 Amniotic fluid, 179 Allergic contact dermatitis (ACD), 1574–1575 Amniotic fluid culture, 185 Allergic rhinitis Amniotomy, 183 classification, 482 Amebiasis, 1143 definition, 481 Amoxicillin, 574 diagnosis, 482–484 Amphetamines, 858 patient approach, 482 physiologic effects of, 776 prevalence, 481 symptom of, 777 prevention, 486–487 Amputation, 1052 treatment, 484–486 Amsel’s criteria, 1355 Alloimmunization, 197 Amylase, 1158, 1160 Allopurinol, 1331, 1713 Amyloid PET scans, 341 Alopecia, 1629 Anencephaly, 75 Alopecia areata, 1630 Anagen, 1629 Alopecia universalis, 1630 Anagen effluvium, 1630 Alpha–1 antitrypsin deficiency, 1079 Anal advancement flap, 1186 Alpha–1 blockers, 970 Anal canal cancers, 1195–1196 α-adrenergic blocker, 1298 Anal canal, anatomy, 1182 α-fetoprotein (AFP), 1171, 1325 Anal fissures α-Glucosidase inhibition, 1661–1662 diagnosis, 1185 Alpha-methyldopa, 157 epidemiology and classification, 1184 1816 Index

Anal fissures (cont.) Ankle sprains, 693–694 treatment, 1185 Ankylosing spondylitis (AS), 897, 1462, 1540–1541 Anal incontinence Anogenital mucosa, 537 background, 1188, 1189 Anorectal abscesses diagnosis, 1188 diagnosis, 1186 surgery, 1189–1190 incision and drainage, 1186 treatment, 1188–1190 pathogenesis and classification, 1186 Analgesia, 930, 1159 treatment, 1186–1187 Anaphylaxis Anorectal fistula anaphylactic triggers, 490 diagnosis, 1187 ancillary studies, 490 pathogenesis and classification, 1187 anesthesia, 493 treatment, 1187–1188 definition, 489 Anorexia, 460 diagnosis, 489 Anorexia nervosa (AN), 459–462 differential diagnosis, 490 Anorexigenic hormones, 701 exercise, 493 Anoscopy, 1183 food, 492 Anovulatory cycles, 1383 history, 490 Anterior dislocation, 1475–1476 idiopathic anaphylaxis, 493–494 Anterior uveitis, 897 immunotherapy, 496 Anthracycline, 1556 insect stings, 493 Antiarrhythmic drug therapy, 986–990 latex, 492 Antibiotic(s), 184, 186, 646–647, 1159 physical exam, 490 acute bronchitis, 514 potential triggers, 490 common cold, 510 prevention, 494, 496 viral infections, 509 rimary treatment, 493–494 Antibiotic choice, 875, 878 secondary treatment, 494 Antibiotic prophylaxis, 1060 vaccine administration, 493 Antibiotic resistance, 530 Anaplastic lymphoma kinase (ALK), 1108 Antibiotic therapy, 524, 878, 930–931, 1056 Anatomic stress incontinence, 320 Antibody (HCAb) to HCV, 1173 Ancylostoma, 1142 Anticholinergics, 855 Androgenic alopecia, 1631 Anticipatory guidance, 15 ® Android , smart devices, 1765 Anticoagulants, 977 Anemia, 672, 1200, 1289, 1719 Anticoagulation, 994, 1046, 1048, 1068 aplastic, 1728–1729 Anticoagulation therapy, 1024 hemolytic, 1727 Anticonvulsants, 465, 857, 879 megaloblastic, 1729–1731 Antidepressant, 853 microcytic, 1723–1727 Antidepressant medication, 456, 858 myelophthisic, 1729 Antidepressants 722, 1390, 1465 non-megaloblastic, 1731 Antiemetics, 852–853 in pregnancy, 158 Antiepileptic drugs (AEDs), 160, 833, 853 sideroblastic, 1726–1727 Antifibrinolytic therapy, 847 sports, 1719 Antifungal agents, 1625 Anemia of chronic disease (ACD), 1720, 1727–1728 Antigen tests, 513 Anemia of chronic inflammation (ACI), 1720, 1727–1728 Antigenic shifts, 511 Anesthesia, 188 Anti-HAVantibodies, 1169 Aneurysmal SAH (aSAH), 846 Antihistamines, 522, 1626 Angina, 974 Antimicrobial agents, 877 Angioedema, 1577 Antimicrobial therapy, 521 Angiokeratoma, 1613–1614 Antineutrophil cytoplasmaic antibodies (ANCA), 1277 Angiokeratoma of Fordyce, 1613 Antioxidants, 1105 Angioplasty, 1237 Antiphospholipid antibody syndrome, 1042 Angiotensin converting enzyme (ACE) inhibitors, 1021, Antiplatelet therapy, 977, 1052 1281 Antipsychotics, 343, 852 Angiotensin receptor antagonists, 969 Anti-seizure medications, 882 Angiotensin receptor blockers (ARBs), 1023, 1281, 1656 Antisocial personality disorder, 464–465 Animal host, 508 Antithrombotic prophylaxis, 1490 Ankle-brachial index (ABI), 1052 Antivenins, 609 Ankle fracture, 1512 Antiviral, 863 Index 1817

Anuria, 1329 Appendicle orifice, 1206 Anxiety, 450, 455, 1386 Appetite, 701 ® Anxiety disorders, 412 Apple , 1765 acupuncture, 420 Application programming interfaces (APIs), 1762 agoraphobia, 414 Apps, 700, 1765 body dysmorphic disorder, 415 Aquagenic urticaria, 1577 complementary and alternative methods, 419–420 Arcus senilis, 1640 cost burden, 420 Arden Syntax, 1765 disinhibited social engagement disorder, 413–414 Aripiprazole, 465, 853 excoriation (skin-picking) disorder, 415 Aromatase inhibitor, 1431, 1432 generalized anxiety disorder, 414–415 Arrhythmias, 1066. See also Cardiac arrhythmias hoarding disorder, 415 Arrhythmogenic right ventricular cardiomyopathy mindfulness, 420 (ARVC), 1062 panic disorder, 414 Arterial embolization, 1124 PTSD, 415–416 Arterial gas embolism (AGE), 654 reactive attachment disorder, 413 Arterial occlusive retinal disease, 919–920 screening tools for, 416–417 Arthritis, 1568 selective mutism, 413 Arthroscopic partial meniscectomy, 1500 separation anxiety disorder, 413 ASD. See Autism spectrum disorder (ASD) social anxiety disorder (social phobia), 414 Aspartate aminotransferase, 1167 specific phobias, 414 Aspiration, 879, 1553 substance/medication-induced anxiety disorder, 415 Aspirin, 72, 84, 843, 1202 treatment, 417–419 Aspirin/salicylates, 625 trichotillomania (hair-pulling) disorder, 415 Assessment categories for mammographic evaluation, yoga, 419 1429 Anxiolytics, 781 Assisted living facilities, 313 Aortic aneurysm, 1463 Assisted vaginal delivery, 187–188 Aortic dissection Assistive services, 312 chest x-ray, 1032 Asthma, 159, 669–670 chronic hypertension, 1032 bronchodilator administration, 1075 classification, 1032 desensitization, 1078 computed tomography, 1033 hypoxemia, 1075, 1078 electrocardiography, 1032 PEF rate, 1075 magnetic resonance imaging, 1033 prevention of exacerbations, 1080–1081 management, 1033 severity, 1075, 1076 symptoms, 1032 spirometry, 1075 transthoracic echocardiography, 1033 symptoms of, 1075 type A, 1032, 1033 Astroviruses, 1144 type B, 1032–1034 Asymptomatic contacts, 524 Aortic regurgitation, 1006–1007 Asymptomatic neurosyphilis, 879 Aortic stenosis, 1005–1006 Asymptomatic patients, 1151 Aorto-mesenteric bypass, 1236 Asymptomatic prostatitis, 1299 Apixaban, 1046 Atelectasis, 1121–1122 Aplastic anemia, 1728–1729 Atenolol, 857 Apnea, 218 Atherogenic dyslipidemia, 1640 ApoA1 Milano, 1639 Atherosclerosis, 1052 ApoB, 1641 Atherosclerotic cardiovascular disease (ASCVD), ApoE, 1641 839, 844 Apolipoproteins, 1637 Atherosclerotic disease, 1237 Apomorphine, 854–856 Athlete’s foot, 1593 Apophyseal avulsion fractures, 272, 273 Athlete’s heart, 1061 Apophysitis, 1492 Athletic injuries, 21 Apophysitis of hip, 273 Atlanta classification, 1159 Appendicitis Atonic seizures, 826 background, 1219 Atopic dermatitis (AD), 1564–1567, 1624 differential diagnosis, 1220 Atopic disease, 1238 history and examination, 1219–1220 Atopic keratoconjunctivitis, 895 investigations, 1220 Atorvastatin (Lipitor), 858 treatment, 1220 Atovaquone, 566 1818 Index

Atrial fibrillation (AF), 728, 1061, 1063 medication used, 476 ablation therapy, 994 pathogenesis/genetic, 469 cardioversion, 993 pathogenesis/neurobiological, 470 definition, 992 patient evaluation, 470, 471 long term treatment of, 993 prognosis, 476 management of, 992, 993 specific domains, 474–475 risk factor, 992 treatment, 474 surgical treatments for, 994 Autism-specific screening, 80 warfarin, 995 Autoimmune hemolytic anemia, 504 Atrial flutter, 995 Autoimmune pancreatitis, 1160 Atrial/sinus tachycardia, 995 Automated Auditory Brainstem Response Atrioventricular arrhythmias, 996–997 (ABR) test, 950 Atrioventricular block (AVB), 996 Autosomal dominant, 1060, 1062 1st degree, 996 Autosomal dominant polycystic kidney disease 2nd degree, 997 (ADPKD), 1281–1282 3rd degree, 997 Avascular necrosis, 1494 Atrophic vaginitis, 1360–1362 Avoidant personality disorder, 465 clinical presentation, 1361 Avoidant/restrictive food intake disorder, 460 diagnosis, 1361 Azithromycin, 529, 565, 574 moderate to severe, 1361–1362 Azoospermia, 1325 treatment, 1361 Attack, 883 Attention deficit/hyperactivity disorder (ADHD), 14 B abuse potential, 257 B12 deficiency, 1730 approved stimulant medications, 258 B12 replacement, 1730 behavioral charts, 257 Baby friendly hospital initiative, 195 cognitive-behavioral treatments (CBT), 257 Bacillus Calmette-Guerin (BCG), 1327 combined, 256–257 Back school, 1466 diversion, 257 Baclofen, 762 evening IR medication, 257 Bacteremia, 556 hyperactive/impulsive, 256 Bacterial conjunctivitis, 890–892 inattentive, 256 Bacterial endocarditis (BE), 1055 and learning disability, 730 management of, 1055 medication holidays, 258 presentation and diagnosis, 1055–1056 medication management, 257–258 Bacterial pericarditis, 1054 prevalence, 256 Bacterial pneumonia stimulant medications, 257 classification, 1084–1086 symptoms, 256 definition/background/epidemiology, 1084 therapeutic level, 257 differential diagnosis, 1088 token economies, 257 history, 1087 Atypical absence seizures, 825 immunizations, 1089 Atypical antipsychotic, 853 laboratory and imaging, 1087–1088 Atypical antipsychotic medications, 464 medications, 1088–1089 Atypical ductal hyperplasia, 1427 patient education, 1089 Atypical hyperplasia, 1421–1422 physical exam, 1087 Audiology, 950 special testing, 1088 Auspitz sign, 1569 Bacterial tracheitis, 246 Autism spectrum disorder (ASD) Bacterial vaginosis (BV), 1352–1356 additional evaluation, 474 diagnosis of, 1355 behavioral therapy, 474 treatment of, 1355 classification, 470 Bactericidal, 1057 clinical evaluation, 471–472 Bacteriuria, 1250 comprehensive intervention programs, 475 Baker’s cyst, 1502–1503 definition, 469 Ballotable head, 189 differential diagnosis, 473 Bannwarth’s syndrome, 573 epidemiology, 470 Barcelona Clinic Liver Cancer (BCLC) staging system, history and examination, 472–474 1177 Index 1819

Bariatric surgery, 161, 706, 1720, 1725 Biopsychosocial stressors, 1459 Barium enema, 1206 Biosynthetic burn dressings, 658 Barometric pressure, 653 Bipolar depression, 435 Barotrauma WHIPLASHED screen, 428 definition/background, 653–654 Bipolar disorders, 423, 427–429, 434–436 history, 654–655 acute treatment, 434–435 laboratory and imaging, 655 bipolar I disorder, 427–429 physical examination, 655 in children & adolescents, 437 prevention, 656 diagnostic criteria, 428 treatment, 655–656 epidemiology, 423–424 Bartholin gland and duct disorders, 1364–1365 FDA approved treatments, 435 Bartonella henselae, 1598 maintenance treatment, 435–436 Basal cell carcinoma, 1608–1609 manic episode, DSM 5 criteria, 427 Basket retrieval, 1329 in older adults, 437–438 Basophilic stippling, 1726 in pregnant and lactating women, 438 Bats, 570 risk and prognostic factors, 424–425 Bear Hugger, 599 BI-RADS, 1414 Bed-bugs, 1599 Birth spacing, 198 Beers Criteria, 323 Bisphosphonates, 1491, 1552, 1689, 1690 Behavioral components, 261 Black dot tinea, 1593 Behavioral marital therapy, 765 Bladder cancer, 1290, 1326 Behavioral strategies, 703 Bladder outlet obstruction, 1304 Behavioral therapy, ASD, 474 Bleeding, 571 Bell’s Palsy (BP), 161, 863, 868 male circumcision, 1314 Bence Jones proteins, 1288 vasectomy, 1317 Benign breast disease, 1411 Bleeding associated with contraceptive method, 1377 Benign breast masses, 1419–1422 Bleeding disorders, 673 Benign epilepsy with centro-temporal spikes acquired bleeding disorders, 1738 (BECTS), 829 congenital bleeding disorders, 1734–1738 Benign familial neonatal seizures, 827 diagnosis and evaluation, 1734 Benign prostatic hyperplasia, urethral stricture, DIC, 1746 urinary infection, 1302 psychosocial concerns, 1737 Benign prostatic hypertrophy (BPH), 1294 thrombocytopenia, 1738–1744 Benzodiazepines (BZDs), 628–631, 638, 761, vascular wall, 1741, 1745 781, 857 Blepharitis, 917 Benzophenones, 1621 Blepharoconjunctivitis, 898 Benztropine (Cogentin), 854 Blepharoptosis, 917 Bereavement, 413 Blindness, 894 Beta-adrenergic agonists, 858 Bloating, 569 Beta amyloid deposits, 341 Blood cultures, 1056 Beta-blockade, 1061 Blood ethanol level, 443 Beta blockers, 857, 969–970, 977, 1022–1023 Blood lead levels, 77 Beta thalassemia trait, 1726 Blood pressure, 82, 964 Bevacizumab, 1207 Blood testing, 483 Bi-articular muscles, 1499 Blood transfusion, 562 Bicep femoris, 1499 Blount’s disease, 280 Biceps tendon rupture, 685–686 Blowout fractures, 909–910 Biceps tendonitis and rupture, 1477 Blunt trauma, 1217 Bichloroacetic acid (BCA), 538 Blurred vision, 899 Bilateral hilar adenopathy, 1124 Board and care facilities, 313 Bile acid sequestrants, 1643 Body dysmorphic disorder, 415, 702 Binge drinking, 757–758 Body lice, 1596 Binge-eating disorder, 459, 462–463 Body mass index (BMI), 82, 107, 700, 839 Biochemical testing, 210 Bone densitometry, 1686–1687 Biofeedback, 1191 Bone density, 1685 Biofeedback training, 1782–1783 Bone fractures, 89 Biomarkers, 341, 703 Bone scintigraphy, 1558 1820 Index

Bony enlargement, 1517 BRCA1, 87, 1419 Booster shots, 74 BRCA2, 87, 1419 Borborygmi, 1239 BRCA1/BRCA2 mutations, 1406, 1408 Borderline personality disorder, 462, 464, 465 BRCA mutation, 1427 Bordetella pertussis, 514 Breast asymmetry, 1429 Borrelia Breast cancer, 87, 1390 B. afzelii, 572 biopsy, 1430 B. burgdorferi (Bb), 572 chemotherapy, 1431 Borrelia lymphocytoma, 572 classification, 1425–1426 Botulinum toxin, 1510, 1551 epidemiology, 1426 Botulinum toxin type A, 857 follow-up care, 1432 Botulism, 1241 history and physical examination, 1429 Bowel ischemia, 1237 laboratory and imaging, 1429–1430 Bowel obstruction prognosis, 1432 background, 1226–1227 radiation, 1431 diagnosis, 1227–1228 risk factors, 1426–1427 prevention, 1229 screening, 1427–1428 treatment, 1228–1229 staging, 1430–1431 Bowel rest, 1237 surgery, 1431 Bowen’s disease, 1609 Breast conserving therapy (BCT), 1430 Bowler’s thumb, 1552 Breast construction, 1432 Boxer’s fracture, 1482 Breast disease during pregnancy, 1422 Braces, 1520 Breast exam, 1413 Brachial plexus, 180 Breast pain, 1415, 1429 Brachial plexus injury, 225 Breast self-awareness, 1428 Bradykinesia, 852 Breast self-examination (BSE), 87, 1412, 1427 BRAF gene, 1203 Breast tenderness, 145 Brain abscesses Breastfeeding, 17–18, 75, 230, 1081 anticonvulsants, 879 promotion of, 194–195 causative agent, 877 ten steps to, 195 clinical signs and symptoms, 878 difficulties, 230 common symptoms, 878 Breech presentation, 179 diagnosis, 878 Breech Trial, 179 direct invasion, 878 Breslow maximum tumor, 1607 drainage of, 879 Brief interventions, 774–776 duration of antimicrobial therapy, 878 Brimonidine, 1573 empiric antibiotic therapy, 878 Bromocriptine, 854, 1417 laboratory studies, 878 Bromocriptine mesylate, 1663 mortality rate, 879 Bromocriptine (Parlodel), 854 neurological sequelae, 879 Bronchial artery embolization, 1126 poor prognostic indicators, 879 Bronchiectasis, 1122–1124 presentation, 878 Bronchiolitis, 244, 246 steroids, 879 Bronchoalveolar lavage, 1121, 1123 treatment, 878–879 Bronchoscopy with biopsy, 1107 triad, 878 B-type natriuretic peptide (BNP), 1018–1019 Brain-derived neurotrophic factor, 343 Buckle, 1480 Brain imaging, 881 Buckle fractures, 272 Brain tumors Budapest criteria, 1551 diagnosis, 881–882 Buffalo hump, 1711 imaging modality of choice, 881 Bulimia nervosa (BN), 459, 462–463 incidence of, 881 Bullous pemphigoid, 1581 maximal safe resection, 882 Bundled payment system, 1788 prognosis and treatment, 882 Bunya virus, 574 signs and symptoms, 881 Bupropion, 1081 types of, 881 Buproprion, 108 Brainstem tumors, 858 Burkitt lymphoma, 504 Branch duct, 1163 Burns, 911–912 Branch retinal vein occlusions (BRVOs), 920 definition/background, 656 Index 1821

physical examination, 656–658 Cardiac imaging, 975–976 prevention, 658 Cardiac syncope. See Syncope treatment, 658 Cardiac tamponade, 1054 Burr cells, 1723 Cardiac troponin, 975 Bush meat, 570 Cardiogenic pulmonary edema, 1112 Butterfly rash, 1626 Cardiogenic shock categories of, 1030 definition, 1030–1031 C management, 1031 CA–125, 1408 myocardial infarction, 1030 Caffeine, 858 pathophysiology, 1030 CAGE questionnaire, 756, 774 Cardiomegaly, 1067 Calcific tendonitis, 1476 Cardiomyopathies (CMs) Calcineurin inhibitors (CI), 1565, 1570, 1626 ARVC, 1062 Calcipotriene, 1570 DCM, 1062–1063 Calcitonin, 1690, 1708 definition of, 1060 Calcium, 105, 1688 HCM, 1060–1062 Calcium channel blockers, 852, 853, 969 PPCM, 1066–1067 Calcium metabolism, 1708–1710 primary CMs, 1060 Calcium oxalate, 1327 primary restrictive nonhypertrophied Calcium phosphate, 1327 cardiomyopathy, 1063 Calcium stones, 1327 secondary CMs, 1060 Calf injuries, 1505–1508 stress cardiomyopathy, 1066 Caliciviruses, 1144 tachycardia induced cardiomyopathy, 1067 Calluses, 1627 Cardiopulmonary resuscitation (CPR), 1031 CALMER approach, 714 Cardiorespiratory exercise, 101 Calorie, 702 Cardiovascular disease (CVD), 1387 Calorie counting, 703 risk factors, 965 Cam and pincer deformity, 1495 Cardiovascular magnetic resonance imaging Cambridge classification, 1161 (CMR), 1061 Campylobacter, 1234 Cardiovascular risk factors, 77, 700 C. jejuni, 1142, 1145 Cardioversion, 986, 993 Cancer genetic risk assessment, 212–213 Care Cancer genomics, 1108 quality, 1787 Candida albicans, 1356, 1594 team, 1789 Candidal balanitis, 1595 total cost, 1787 Candidal diaper rash, 1595 Carotid endarterectomy (CEA), 839 Candidal intertrigo, 1595 Carotid stenosis, 839, 844 Candidal vaginitis, 1352 Carpal fractures, 1481 Candidal vulvovaginitis, 1595 Carpal tunnel syndrome (CTS), 161, 862–864 Candidate vendors, 1760 Cartilage cap, 1553 Candidiasis, 939–940, 1356–1358 Cascade screening, 1646 Capsaicin, 1519 Case-fatality, 555 Captopril Diabetic Nephropathy Study, 1656 Cat, 562 Caput succedaneum, 224 Cat scratch disease (CSD), 1598 Carbamazepine (Tegretol), 762, 858, 863 Cataracts, 923 Carbidopa, 854, 855 Catechol-O-methyl transferase (COMT) inhibitors, 855 Carbon monoxide (CO) poisoning, 601 Cathartics, 617 Carbuncles, 1587–1588 Catheter-associated UTI (CAUTI), 1249 Cardiac arrhythmias, 844 Cauda equina syndrome, 1459 electrophysiology, 984–985 Cauterization, 957 evaluation of, 985–986 Cavernous hemangioma, 1612 patient evaluation, 985 Cecal intubation rate, 1205 referral to cardiologist, 991 Cefotetan, 533 surgery, 991 Cefoxitin, 533 treatment options for, 986–991 Ceftriaxone, 533, 574 ventricular arrhythmias, 997–999 Cefuroxime, 574 Cardiac biomarkers, 975 Cellulitis, 1586–1587, 1589 1822 Index

Centers for Disease Control (CDC), 545, 1092 Child abuse Centers for Medicare and Medicaid Services (CMS), 1761 anal exam, 362 Central artery occlusion (CRAO), 919–920 barriers, 363 Central diabetes insipidus, 1705–1706 bridging veins, 361 Central retinal vein occlusions (CRVOs), 920 bruise, 359 Central sensitization, 1547 burn, 359–360 Central slip injuries, 1486 consultation, 364 Cephalhematoma, 224 CT, 361 Cephalic twin, 179 curbsides, 364 Cephalohematoma, 188 disclosure, 358, 362 Cephalopelvic disproportion, 183 effects, 358 Cephalosporins, 1146 failure to thrive, 363 Cerebellar tremor, 856, 858 forensic interview, 361 Cerebral arterial vasospasm, 847 fracture, 360 Cerebral palsy, 185 intracranial injury, 360 Cerebral perfusion pressure (CPP), 845 mandated reporting, 358 Cerebral vascular accidents, 728 mechanics, 360 Cerebrospinal fluid (CSF), 875–876 medical neglect, 363 cultures, 878 medical, 362–363 intracranial lesions, imaging for, 875 MRI, 361 opening pressure, 875 neglect, 363–364 relative contraindications, 875 normal examination, 362 Cerebrotendinous xanthomatosis (CTX), 1640 normal variations, 362 Cerebrovascular disease, 837–847, 853 obesity, 363 Certified EHR, 1761 offenders, 358 Cervical cancer, 87, 505 patterned burn, 359 classification, 1401 Period of Purple Crying, 364 definition, 1400 physical abuse, 358–359 diagnosis, 1401 retinal hemorrhages, 361 epidemiology, 1400 risk factors, 357 prevention, 1405–1406 skeletal survey, 359, 360 risk factors, 1400 trafficking, 361 screening, 1402–1405 Child care, 234 treatment, 1401–1402 Child survivors, 447 Cervical friability, 532 Childbearing, 89 Cervical motion tenderness, 532 Childhood stage Cervical radiculopathy, 1467–1468 cognitive achievement, 19 Cervical spondylotic myelopathy, 1469–1470 developmental disabilities, 19 Cervicitis, 1351–1368 gross and fine motor coordination, 18 Cesarean delivery, 179 growth curves, 18 Cesarean section, 178 language development, 19 Cestoda, 1142 learning disabilities, 19 Cetirizine, 896 social skills, 19 CETP inhibitors, 1646 Children, 101–102, 722 Cevimeline, 954 IPV, 371 CFS like illness, 721 Chiropractic care, 1777–1778 Chalazion, 917 Chlamydia, 83, 88, 528–529 Charcot-Marie-Tooth, 871 Chlamydia trachomatis, 894 “Chemical” meningitis, 876 Chlamydial conjunctivitis, 894–895 Chemical pleurodesis, 1118 Chlamydial infection Chemoprophylaxis, 406–407, 876 general principles, 1090 Chemosis, 890 history and physical exam, 1090 Chemotherapy, 1630 laboratory and imaging, special testing, 1090 Chemotherapy-induced peripheral neuropathy, 869 prevention, 1090 Cherry anigoma, 1613 treatment, 1090 Chest pain, 974, 1053, 1055, 1065 Chloramphenicol, 567 Chest tube, 1117 Chlordiazepoxide, 761 Chickenpox, 248 Chloroquine, 1126 Chiggers, 1598 CHOICE project, 1339 Index 1823

Cholelithiasis and cholecystitis prevention of exacerbations, 1080–1081 background, 1220–1221 pulmonary function testing and spirometry, 1079 differential diagnosis, 1222 pulmonary rehabilitation, 1081 history and examination, 1221–1222 spacer, 1081 investigations, 1222 sputum, 1079 pathophysiology, 1221 Chronic otitis externa, 934 treatment, 1222–1223 Chronic pain, 415, 787 Cholestanol, 1641 treatment algorithm, 789 Cholesteryl ester storage disease aka LAL (lysosomal Chronic pancreatitis, 1160–1162 acid lipase) deficiency, 1640 Chronic pelvic pain (CPP) Cholesteryl ester transfer protein (CETP), 1638 definition, 1441 Cholinergic urticaria, 1577 diagnosis and management, 1443–1444 Cholinesterase inhibitors (CIs), 343 history, 1441–1442 Chondroitin, 1520 imaging, 1442–1443 Chondroma, 1554 laboratory analysis, 1442–1443 Chondrosarcoma, 1557 physical exam, 1442 Chordoma, 1557 surgical interventions, 1444 Chorioamnionitis, 184–185 treatment of, 1444 Chorionic villous sampling (CVS), 145 Chronic Prostatitis Collaborative Research Network Chorioretinitis, 563 (CPCRN), 1303 Chromosomal and genetic disorders, 208, 209 Chronic prostatitis/chronic pelvic pain syndrome, 1299 Chromosomes, 206 Chronic rhinosinusitis, 519–522 Chronic abdominal pain, 1212 Chronic risk, 444 Chronic abnormal uterine bleeding, 1371 Chronic seizure disorder, 824 Chronic active EBV infection (CAEBV), 502, 504 Chronic sinusitis, 484 Chronic bacterial prostatitis, 1299 Chronic somatization, 452–453 Chronic carriers, 524 Chronic starvation, 461 Chronic cough, 1074 Chronic thromboembolic pulmonary hypertension Chronic disease(s), 512, 700 (CTEPH), 1068 Chronic disease model, 795 Chronic traumatic encephalopathy, 341 Chronic fatigue syndrome (CFS), 504, 719 Chronic urticaria, 1577 Chronic hamstring, 1500 Chronological evolution, of family medicine, 1805–1810 Chronic HCV infection, 1172 Chylomicrons, 1638 Chronic hypertension, 154, 156–157 Cicatricial alopecia, 1630–1631 Chronic illness, 39–40 Cigarette smoking, 1078–1079, 1103, 1104, 1326 Chronic inflammatory demyelinating neuropathy, Ciguatera, 1240 862 Ciliary flush, 898 Chronic inflammatory demyelinating Cilostazol, 1053 polyradiculoneuropathy, 868 Cimex lectularius, 1599 Chronic injuries, 1500 Cinnarizine, 853 Chronic interstitial nephritis (CIN), 1283 Ciprofloxacin, 1145 Chronic kidney disease (CKD), 1287–1289, 1728 Circadian rhythm, 730 Chronic liver disease, 1728 Circadian-rhythm sleep disturbance, 726 Chronic low back pain, 1456, 1467 Citalopram, 344, 853 Chronic meningitis Clark’s nevus, 1604 clinical presentation, 875 Classical incision, 178 definition, 875 Classification Criteria for Psoriatic Arthritis (CAPSAR) Chronic mesenteric ischemia, 1237 scoring system, 1541 Chronic myocarditis, 1065 Claudication, 1052 Chronic noncancer pain (CNCP), 787 Clavicle, 1474–1475 Chronic obstructive pulmonary disease (COPD) Clavicular fractures, 1474 alpha–1 antitrypsin, 1079 Clebopride, 853 anticholinergic, 1080 Clindamycin, 565 cigarette smoking, 1078–1079 Clinical breast examination (CBE), 1412–1413, 1427 exacerbation, 1080 Clinical decision aids, 1763 family and community issues, 1081 Clinical informatics inhaled short acting beta–2 agonists, 1080 clinical decision support (CDS) tools, 1763–1765 physical examination, 1079 electronic records, 1759–1763 prednisone, 1080 learning health system, 1767–1768 1824 Index

Clinical informatics (cont.) laboratory and imaging, special testing, 1096 patient portals, 1765–1766 prevention, 1096–1097 population health, 1766–1767 treatment, 1096 as specialty option, 1768 Codman’s triangle, 1556 standards, 1765 Cognitive achievement, 19 telehealth, 1766 Cognitive behavior therapy (CBT), 395, 420, Clinical Institute Withdrawal Assessment–A revised 456, 461–465, 721, 726, 765, 858, 1466 (CIWA-Ar), 760 Cognitive components, 261 Clinical presentation Cognitive deficits, 559 rhinosinusitis, 520 Cognitive enhancers, 343 tonsillopharyngitis, 523 Cognitive functions, 1547 Clinical prevention Cognitive impairment, 291 adherence, 89–96 Cognitive restructuring, 436 coding and billing difficulties, 94 Cognitive stimulation, 342 counseling, 84, 87 Cogwheeling, 852 cultural and demographic factors, 95 Colchicine, 1054 health literacy, 94–95 Cold injury, 598–599 health promotion, 74 active internal rewarming, 599 immunization, 74–75, 83–84 active rewarming, 598 patient adherence, 94 causes, 598 practice culture, 94 Frostbite and NFCI, 599 preventive care visit, 94 passive rewarming, 598 preventive services, 94 pathophysiology of, 599 primary, 71, 77 Cold sore, 1591 prophylaxis, 75, 84 Cold urticaria, 1577 secondary, 71, 72 Colesevelam, 1663 tertiary, 71 Colic, 231–232 time constraints, 92 Collagenase, 1553 training needs, 92–94 Colles’ fracture, 1481 training & time, 95 Colonoscopy, 1150, 1183, 1200, 1228 Clinically Integrated Networks (CIN), 63 Colorectal cancer (CRC), 88, 1199–1208 Clobetasol propionate, 1630 Colposcopy, 1405 Clonazepam, 857 Combined behavioral intervention, 765 Clonidine, 762, 970, 1390 Combined hormonal contraceptives (CHCs), Clopidogrel, 843 1343–1346 Closed globe injuries, 907 Combined oral contraception (COC), 198 Closed hemorrhoidectomy, 1184 Comedolytic agents, 1571 Closed loop obstruction, 1226 Common cold, 509–510. See also Upper respiratory Clostridium botulinum, 1241 tract infections (URTIs) Clostridium difficile, 1060, 1146–1147, 1234, 1235 Common Warts, 1592 toxins, 1234 Community acquired pneumonia (CAP), 244, Clozapine, 853 1084, 1086 Clue cells, 1353, 1354 Community-acquired methicillin resistant Cluster A personality disorders, 464 Staphylococcus aureus (CA-MRSA), 1587 Cluster B personality disorders, 464–465 Community economic hardship, 723 Cluster C personality disorders, 465–466 Community-oriented Primary Care (COPC), 65 Cluster headache, 817 Community resources, infant risk factors, 236 Coagulopathies, 956 Community supports, 333 Coarctation, 966 Compartment syndrome, 657, 658 Cobalamin, 1729 Complementary and alternative medicine (CAM), 1771 Cocaine Complementary therapies, 524 addiction/dependence, treatment of, 778 Complete heart block, 1066 causes, 777 Completed suicide, 441 complications of, 777–778 Complex chronic diseases, 1790 crack cocaine, 776 Complex regional pain syndrome (CRPS), 1551–1552 Coccidioidomycosis Complications, influenza, 512 definition/background and epidemiology, 1096 Complications of GAS tonsillopharyngitis, 523–524 history and physical examination, 1096 Comprehensive care, 7 Index 1825

Comprehensive intervention programs, 475 Conservative management of degenerative tears, Comprehensive stroke center, 841 1502 Compression stockings, 1048 Conservative measures, 1188 Compression ultrasound (CUS), 1045 Consortium of Academic Health Centers for Integrative Compressive neuropathies, 862 Medicine (CAHCIM), 1771 Computed tomographic angiography (CTA), 841, 847 Constipation, 143, 308–309, 462, 801–802 Computed tomographic pulmonary angiography non-pharmacologic management, 309 (CTPA), 1045 pharmacologic management, 309 Computed tomography (CT), 521, 599, 812, 1161–1162, primary, 308 1164 secondary, 308 colonoscopy, 1204, 1206 Constrictive pericarditis, 1053–1054 enteroclysis, 1228 Consumerism, 1788 guided needle biopsy, 1107 Contact dermatitis, 1574–1576 myelogram, 1461 Contact lenses, 896 myelography, 1470 Contact ocular allergy, 895 COMT inhibitors, 855 Contact urticaria, 1577 Concussion, 681–682 Continuing-Care Retirement Communities Condoms, 541 (CCRCs), 313 Conduct disorder (CD), 260–261, 464 Continuity, 1789 adolescent onset, 260 Contraceptive(s), 1396, 1398 aggression towards people/animals, 260 CHOICE project, 1339 childhood onset, 260 combined hormonal, 1343–1346 cognitive-behavioral treatments (CBT), 261 decisions, 1336 community factors, 261 diaphragm, 1346 deceitfulness/theft, 261 effectiveness, 1337, 1338 destruction of property, 260 emergency, 1342–1343 environmentally, 261 injectable, 1341–1342 medications, 262 permanent methods, 1347 prevalence, 261 subdermal contraceptive implants, 1340–1341 rates, 261 Contraction stress test, 148 serious violations of rules, 261 Contrast imaging, 1192 symptoms, 261 Contrast induced AKI (CI-AKI), 1284–1287 unspecified onset, 260 Contrast-enhanced CT (CECT), 1158 Conductive hearing loss, 948 Contusions, 1499 Condyloma accuminatum Coomb’s test, 224 background, 1194 Copper deficiency, 871 diagnosis, 1194–1195 Copper IUD, 1339 prevention, 1195 CoQ10, 1646 screening, 1195 Cor pulmonale. See Pulmonary hypertension (PH) treatment, 1195 Core needle biopsy (CNB), 1414 Condylomatous warts, 1592 Corneal abrasions and foreign bodies, 905–906 Confidentiality, 46 Corneal blindness, 898 Conflict, 45 Corneal swelling, 899 Congenital abnormalities, 916–917 Corns, 1627 Congenital hearing loss, 78 Coronary angiography, 976 Congenital heart disease, 1115 Coronary artery disease (CAD), 973, 976, 978, 1016 Congenital hypothyroidism (CH), 78, 1679 Coronary heart disease, 973 Congenital nevus, 1604 Coronary vascular disease (CVD), 1389 Congenital toxoplasmosis, 562–566 Coronaviruses, 242, 510 Congestive heart failure, 728, 1119 Corrected reticulocyte percentage, 1723 Conjugated equine estrogen, 1388 Corticosteroid(s), 858, 863, 882, 884, 955, 1054, 1175, Conjunctiva, 918 1519, 1529, 1630 Conjunctival injection, 890 Corticosteroid therapy, 1113 Conjunctivitis Cosleeping, 18 allergic, 895–896 Cost, sepsis treatment, 555 bacterial, 890, 892, 893 Cough, 513 chlamydial, 894–895 Cough etiquette, 515 viral, 892–894 Counseling, 75, 77–78, 721 1826 Index

Counseling strategies, 436 Cytokine system, 452 Counter-transference, 715 Cytomegalovirus (CMV), 502 Couples-based therapy (CBT), 765 infection, 562 Covered services, 314–316 Cow’s milk protein allergy, 1239 COX–2 inhibitors, 1519 D Coxsackie A16, 248 Dacryoadenitis, 919 Coxsackievirus, 1063 Dacryocystitis, 919 C-peptide, 1650 Danazol, 1416 ® CPT , 1765 Danger signs, 143 CRAFFT, 83, 756 Dapsone, 1627 C reactive protein (CRP), 509, 1547 Darbapoietin, 1728 Creatinine, 575 Darkfield examination, 880 Creatinine clearance (CrCl), 1663 Dark urine, 1163 Creighton model natural family planning system, Daycare, 514 1347 Daytime sleepiness, 726–727, 730 Crepitus, 1517 D-dimer testing, 1045 Crescent glomerulonephritis, 1277 Dead space, 639 Crisis intervention, infant risk factors, 234 Deamino-γ-D-arginine vasopressin (DDAVP), 1737 Critical limb ischemia (CLI), 1052 Death rattle, 802 Critical Practice Audit, 715 Decision aids, 56 Crohn’s disease (CD), 1152, 1363–1364 Decision support tools, 1759 Croup, 245, 246 Decongestants, 521, 957 Croup tent, 245 Deep brain stimulation (DBS), 436, 856, 857 Crusted scabies, 1597 Deep breathing, 1775 Cryoglobulins, 1281 Deep somatic pain, 1550 Cryotherapy, 538, 1620 Deep vein thrombosis (DVT) Cryptoglandular infections, 1186, 1187 pretest probability for, 1044 Cryptorchidism, 1323 symptoms, 1042 Cryptosporidium, 250 venography, 1045 CSF, 536 Well’s criteria, 1043 “C” sign, 1498 Deep venous thrombosis (DVT), 157, 841 CT. See Computed tomography (CT) DEET, 568 CT angiography. See Computed tomographic Defeminization, 1708 angiography (CTA) Degeneration, 1521 Cubital tunnel syndrome, 864 Dehydration, 250, 953 Cullen’s sign, 1158 Delayed cerebral ischemia (DCI), 847 Culture, 28, 29, 31–32 Delayed ejaculation, 752 rhinosinusitis, 521 Delayed pressure urticaria, 1577 spiritual and religious, health care issues, 33 Delayed puberty, 1707 tonsillopharyngitis, 523 Delirium tremens, 760 Cured items, 1241 Delivery, 150–151 Curettage, 1620 Delorme procedure, 1191 Cushing syndrome, 1711 Delusional parasitosis, 1598 Cutaneous drug reactions (CDR), 1579–1581 Dementia, 23, 339–346, 853–854, 1389 Cutaneous leishmaniasis, 1590 diagnostic criteria, 340 Cyclic antidepressants, 622–625 reversible, 340 Cyclosporine (Sandimmune), 858 Dementia with Lewy bodies (DLB), 853 Cyclothymic disorder, 428 Dendritic ulcer, 898 Cyst(s), 1420 Dental caries, 937–938 fluid cytology, 1162 Dental evaluation, 1058 size, 1162 Dental home, 82 Cystectomy, 1327 Dependent personality disorder, 465–466 Cystic masses, 1553 Depigmentation, 1624 Cystic nodular acne, 1571 Depo-Provera, 1341–1342 Cystoscopy, 1326 Depression, 89, 1386 Cytogenetic testing, 210 and anxiety, 726 Index 1827

with anhedonia, 442 Diabetic ketoacidosis (DKA), 1666–1667 Depressive disorders, 423–438 Diabetic kidney disease, 1288 in children & adolescents, 437 Diabetic neuropathy, 868–869 counseling strategies, 436 Diabetic retinopathy, 920–921 deep brain stimulation (DBS), 436 Diagnosis, rhinosinusitis, 520 diagnostic criteria, 425–429 Diagnostic and Statistical Manual of the American ECAPSS, 425 Psychiatric Association 5th Edition (DSM5), 425 Electroconvulsive Therapy (ECT), 436 Diagnostic mammography, 1413 epidemiology, 423–424 Diagnostic peritoneal lavage (DPL), 1218 major depressive disorder, 425–427 Diagnostic technologies, 1107 Monoamine Oxidase Inhibitors, 431 Dialectical behavioral therapy (DBT), 463–465 in older adults, 437–438 Dialysis, 1287–1288 other antidepressants, 431 Diaphragms, 1346 persistent depressive disorder, 425 DIAPPERS, 320 in pregnant and lactating women, 438 Diarrhea, 250, 569, 1234 psychological therapies, 436 Diarrhea prophylaxis, 117–118 risk and prognostic factors, 424–425 Diastolic dysfunction, 1063 selective serotonin reuptake inhibitors, 431 Diathesis-Stress Model, 390 social treatments, 437 Diazepam, 761 tricyclic antidepressants, 431 Diet, 40, 73 Unspecified, 425 Diet and exercise, 1105 Depressogenic cognitive styles, 424 Dietary approach to stop hypertension (DASH) eating De Quervain’s tenosynovitis, 1482 plan, 964 Dermatitis, 917 Dietary interventions, 40 Dermatobia hominis, 1599 Dietary modifications, 1330 Dermatofibroma, 1615–1616 Diet-based therapies, 1779–1780 Dermatophytoses, 1593–1594 Differential diagnosis, 558 Dermatoses, 1363 Difficult patient, care of Dermoscopy, 1605, 1608 active listening, 713 Desmoteplase, 843 approach, 710 Determinants of health, 96 behavioral problems, 710 Developmental delay, 288–290, 413 BREATHE OUT process, 715 Developmental dysplasia of hip (DDH), 281 CALMER approach, 714 Developmental milestones, 82 definition, 709 Developmental stress, 15 dependent clingers, 711 Developmental surveillance, 287–290 diagnosis, 710–712 Dexamethasone, 565, 875 entitled demanders, 711 Dexamethasone suppression test, 1711 epidemiology, 709 Dexmedetomidine, 638 family and community issues, 716 Diabetes, 88, 154, 671–672, 866–867, 1163, 1327 Kleinman’s explanatory model, 713 Diabetes Control and Complications Trial (DCCT), manipulative help rejecters, 711 1652 patient-driven themes/frustrations, 711 Diabetes in pregnancy, 158–159 perpetuating factors, 712 Diabetes mellitus (DM), 160 physician characteristics, 711 definition of DM control, 1652–1653 physician self-care, 714–715 diagnostic criteria for, 1649–1650 precipitating factors, 712 exercise, 1654 predisposing factors, 712 foot problems, 1657–1658 self-destructive deniers, 711 glycemic goals, 1653 Diffuse anterior scleritis, 897 HBGM, 1653 Diffusion weighted MRI, 840 insulin, 1654–1655 DIGFAST, 427 macrovascular disease, 1657 Digital palpation, 1547 medical nutrition therapy, 1653–1654 Digital rectal examination (DRE), 1183, 1296 nephropathy/hypertension, 1656–1657 Digital subtraction angiogram (DSA), 847 pathophysiology, 1651–1652 Digoxin therapy, 1023–1024 retinopathy, 1655–1656 Dihydrotestosterone, 1298 Diabetic amyotrophy, 868 Dilated cardiomyopathy (DCM), 1062–1063 1828 Index

Dimercaptosuccinic acid (DMSA), 1246 Dry eye, 918–919 Dinoflagelletes, 1241 Dry mouth, 954 Dipeptidyl peptidase IV (DPP-IV) inhibitors, 1663 Dry needling, 1551 Diphtheria, 245 DSM–5 diagnostic criteria, autism spectrum Dipyridamole, 844 Disorder, 471 Direct primary care (DPC), 13 DSM5 hypomanic episode, 427–428 Direct thrombin inhibitors, 1048 Dual energy x-ray absorptiometry (DEXA), 1461, 1687 Direct to consumer (DTC) testing, 210–211 Ductal carcinoma in-situ, 1425 Disabled persons, IPV, 372 Ductal obstruction, 1160 Discoid SLE, 1626 Duke criteria, 1056–1057 Disease-oriented evidence, 51 Duloxetine, 1550 Disinhibited social engagement disorder, 413–414 Dupuytren’s contracture, 1484, 1552–1553 Disopyramide, 1038 Durable power of attorney, 1109 ® Disparities, 29–30 DynaMed , 1765 Disruptive sleep patterns, 1547 Dysbetalipoproteinemia, 1639 Disseminated gonococcal infection, 530 Dysfunctional voiding, 1296 Disseminated intravascular coagulation (DIC), 1746 Dyshydrotic eczema, 1564 distal radius fractures, 1480–1481 Dyslipidemias, 1637–1646 Distal tibia fracture, 1512 Dysmenorrhea, 1379–1380, 1438–1439 Distal tip fractures, 1484 Dysmetria, 858 Disulfiram, 767 Dyspareunia, 1356, 1385 Diuretic use, 1284 Dyspepsia Diuretics, 968, 1020–1021, 1281 anti-acid medications, 1132 Diverticulosis, 1150 definition, 1131 Divorce, 388 epidemiology, 1131–1132 DMARDs, 1529–1530 patient characteristics, 1132 DNA hypomethylation, 1203 Dysphagia, 955 DNA methylation, 214 Dysphonia, 954–955 Dog-ear repair, 643 Dyspnea, 802, 1017, 1068, 1112, 1118 Domeboro’s solution, 1595 Dyssynergia, 858 Domperidone, 853 Dysthymic disorder, 425 Dopamine, 855 Dystocia, 179, 183–184 agonists, 854–855 Dystonia, 858 depleters, 853 Dystonic tremor, 856, 858 precursors, 855 Doppler-guided transanal hemorrhoidal ligation, 1184 E Doppler imaging, 1061 Ear, 947–958 Double depression, 425 Early disseminated disease, 573 “Double-sickening” 520 Early hospital discharge, 226–230 Doxazosin, 1298 Early latent syphilis, 535–536 Doxycycline (Vibramycin), 118, 529, 533, 567, Early localized disease, 572 574, 877 Early menopause, 1384 azithromycin, and clarithromycin, 1303 Early-onset neonatal disease, 184 Dravet syndrome, 828–829 Early repolarization, 1054 Driving, 20 Early symptomatic neurosyphilis, 879 Drowning, 77 Easy bruising, 1738 Drowning and submersion injury Eating disorders, 702 definition/background, 651–652 Eaton-Lambert syndrome, 1107 epidemiology, 652 Ebola, 570–572 history, 652 EBV–1, 501 physical exam, 652–653 EBV–2, 501 prevention of, 653 ECAPSS, 425 treatment, 653 Eccentric strengthening, 1510 Drug-and metabolic-induced tremor, 858 Echinacea, 510 Drug-Induced Liver Disease, 1175–1176 Echocardiogram, 1059 Drug induced Parkinsonism (DIP), 852–853 Echoviruses, 1235 Drug-induced tremor, 856 E-cigarettes, 109 Drug metabolism, 212 Ecologic model of intervention, infant risk factors, 236 Index 1829

Economic burden, 447, 1546 Emerging interventions, 769 Ectopic pregnancy, 1463 Emotional components, 261 diagnosis, 167–168 Emotions, 45 epidemiology, 167 Empathy, 714 etiology, 167 Empiric antibiotic therapy, 878 management, 168 Empty nest, 22 prevention, 168 Encephalitis, 503 Ectropion, 916–917 cerebrospinal fluid analysis, 876–877 Eczema. See Atopic dermatitis (AD) computerized tomography (CT), 877 Eczema herpeticum, 1590 differential diagnosis, 876 Edema, 1278 etiology, 876 Effective volume, 1283 history, 876 EHR–2020 Task Force, 1761 magnetic resonance imaging (MRI), 877 Eisenmenger syndrome, 1337 morbidity and mortality, 877 Ejection fraction, 1061 physical exam findings, 876 Elbow, radial head fractures, 1478 presentation of, 876 Elder abuse, 89 Encouraged electronic health record (EHR), 61 assessment of, 349–350 End of life decision making, 46 categories, 348 End-of-Life Pain Management, 800 community services, 351 End-of-Life patient communication, 798 definition of, 347–348 Endometrial biopsy (EMB), 1398 management, 350–351 Endometrial carcinoma patient-related barriers, 349 classification, 1397 physician barriers, 349 definition, 1397 prevention of, 351 diagnosis, 1398–1399 reporting guidelines, 351 epidemiology, 1397 risk factors, 348–349 risk factors, 1397 Elder Abuse Suspicion Index (EASI), 350 treatment, 1400 Elderly, 675–676, 722–723 Endometriosis, 1443 Elderly patients, 1213 definition, 1445 Elective induction, 184 inflammatory nature, 1446 Elective repeat cesarean, 178 pathogenesis, 1445 Electrical injury, 600 treatment of, 1446–1447 Electrical status epilepticus of sleep (ESES), 829 Endometritis, 196, 1437 Electricodesiccation, 1620 Endomyocardial biopsy (EMB), 1063, 1066 Electrocardiography (ECG), 1019 Endomyometritis, 185 changes, 777 Endoscopic retrograde cholangiopancreatography Electroconvulsive therapy (ECT), 436 (ERCP), 1159 Electrolysis, 899 Endoscopic sleeve gastroplasty (ESG), 706 Electrolyte disturbances Endoscopic ultrasonography (EUS), 1161–1162, 1164 calcium, 1271 Endoscopic ultrasound, 1162 magnesium, 1270 Endoscopy, 1205 phosphate, 1270–1271 Endosteal scalloping, 1557 Electrolyte imbalance, 571 Endothelin receptor antagonists, 1116 Electronic health records (EHR), 1759–1762, Endovascular treatments, 843 1765–1766 End stage renal disease, 1276 Electronic medical records (EMR), 41, 94 Energy, 701 Electrophysiology of heart, 984–985 Enhanced physiologic tremor, 857–858 Elevated intraocular pressure, 899 Entacapone (Comtan), 854 Embolus, 838 Entamoeba, 1143 Embryonic stage Entamoeba histolytica, 1142 early toxin exposure, 16 Enteroadherent, 1144 folic acid, 16 Enterobiasis, 251 formation of anatomical structures, 16 Enterobius vermicularis, 251 neural tube defects, 16 Enterohemorrhagic Escherichia coli (EHEC), teratogenic illnesses, 16 1144, 1234, 1235 Emergence phenomenon, 638 Enterotoxigenic Escherichia coli, 250 Emergency contraception (EC), 382, 1342–1343 Entropion, 895, 916 Emergency Medical Services (EMS), 839 Enuresis, 730 1830 Index

Environmental factors, 1546 Estrogen deficiency, 1387 Enzyme linked immunosorbent assay (ELISA), 564 Estrogen receptor, 1431 Eosinophic granulomatosis with polyangiitis, 1277 ESWL, 1329 Eosinophilia, 121, 568 Ethics and privacy laws, 214–215 Eosinophilic esophagitis, 1238 Ethinyl estradiol, 1345 Epicondylitis Ethnicity, 28, 33 lateral epicondylitis, 1479 Etiology, tonsillopharyngitis, 522–523 medial epicondylitis, 1479 Etomidate, 638 Epidemiology European League Against Rheumatism (EULAR) rhinosinusitis, 519 recommendations, 1535 tonsillopharyngitis, 522 EUS, See Endoscopic ultrasonography (EUS) Epidemiology of Diabetes Intervention on Eutectic mixture of local anesthetics (EMLA) Complications (EDIC) trial, 1652 cream, 1315 Epidermal cyst, 1617–1618 Euthanasia, 803 Epidermal growth factor receptor (EGFR), 1108 Euthyroid sick syndrome, 1679 Epididymal cyst, 1322 Evaluation and Management (E&M) coding, 1761 Epididymitis, 1302, 1321 Evidence-based medical care, 556 Epididymo-orchitis, 1322 Evidence-based medicine, 49–57 Epidural analgesia, 178 Ewing’s Sarcoma (EWS), 1555 Epigenetics, 214 Exacerbations, 884 Epiglottitis, 245–246 Exanthem, 1579 Epilepsy, 824 Exchange transfusion, 224 clinical manifestations, 825 Excisional biopsy, 1414, 1620 definition, 824 Excoriation (skin-picking) disorder, 415 prevelance, 824 Exercise, 342, 1518 types, 824–825 (see also Seizures) induced anaphylaxis, 1577 Epinephrine, 494, 858 physiology, 668–669 Epiphora, 918 prescription, 103 Episcleritis, 896 programs, 703 Episodic therapy, 540 tolerance testing, 976 Epistaxis, 956–957 Exostosis, 1553 Epithelial carcinoma, 1406 Expedited partner therapy, 529, 531 ® Epocrates , 1765 Explanatory models, 42 Epstein-Barr Virus (EBV), 501–505, 562 External validity, 51 Erectile dysfunction (ED), 750–751, 1299, 1703 External ventricular drainage, 847 Erikson, Eric, 16, 20–21, 23 Extracorporeal shock wave lithotripsy Eruptive xanthomas, 1640 (ESWL), 1329 Erysipelas, 1586 Extrasphincteric tract, 1187 Erythema, 1625 Extravaginal torsion, 1311 Erythema infectiosum, 247 Eye exam, 904 Erythema Migrans (EM), 572 Eyelid dermatitis, 1575 Erythema multiforme, 248–249, 1579 Eyelid lacerations, 906 Erythema nodosum, 1124 Eyelid myoclonia, 825 Erythrasma, 1589–1590 Ezetimibe, 1643 Erythrocyte sedimentation rate, 1547, 1556 Erythroderma, 1569 Erythromycin, 892 F Erythromycin ethylsuccinate, 895 FABER test, 1459 Erythromycin ophthalmic ointment, 75 Facility living, 334 Erythroplakia, 1618–1619 Factitious disorder, 453, 455 Erythroplasia of Queryat, 1609 Factor V Leiden mutation, 1042 Erythropoiesis-stimulating agents (ESAs), 1728 Factor X a inhibitor, 1048 Erythropoietin, 1728 FADIR, 1495 Escherichia coli, 1142 Failure to thrive (FTT), 232–234, 1239 ESES See Electrical status epilepticus of sleep Fall prevention, 1689 Essential tremor (ET), 856–858 Falls, 322–324 Established urinary incontinence, 320–321 False positive findings, 1106 Estimated glomerular filtration rate (eGFR), 1663 Famciclovir, 540 Estrogen agonist/antagonists, 1690 Familial adenomatous polyposis (FAP), 1201 Index 1831

Familial cancer syndrome, 1408 Febrile seizures, 828 Familial combined hyperlipidemia, 1639 complex, 828 Familial combined hypolipidemia, 1639 simple, 828 Familial hypercholesterolemia, 1639 Fecal DNA, 1204 Familial mixed hyperlipidemia, 1639 Fecal immunochemical testing (FIT), 1205 Family and community issues, 56–57 Fecal leukocytes, 1234 Family-based lifestyle, 77 Federal Medical Leave Act (FMLA), 585 Family caregiving, 39, 46 Federation of State Medical Boards, 1766 Family-centered approach, 7 Fee for service, 1787 Family centered care, 142 Feeding, 80 infant risk factors, 236 Feeding tubes, 345 Family folders, 41 Feldenkrais technique, 1783 Family hardship, 723 Fellowship program, 1768 Family history, 42 Fellowship training program, 1768 Family issues of diseases of the liver, 1178 Felon, 1487 Family medicine Female athlete triad, 1373–1374 ABFM definition, 7 Female infertility advancements, 7–8 definition, 1447 aging population, 11 ovulation disorders, 1449 clinical encounter, 8 peritoneal causes, 1450 clinical practice complexity, 9 treatment, 1450 commercialization, 10 tubal obstruction and abnormalities, 1450 globalization, 11–12 unexplained infertility, 1450–1451 health policy, 12 uterine abnormalities, 1449 human relationships, 11 Female sexual interest/arousal disorder, 749 literature heritage, 8 Femoral anteversion, 279 telemedicine and healthcare technology, 9 Femoral neck stress fractures (FNS), 1492 in United States, 5–6 Femoral Neuropathy, 865 Family physician, 51. See also Physician, family Femoroacetabular impingement, 1494–1496 Family practice approach, 4 Ferriman-Gallwey score, 1708 Family strain, 388 Ferritin, 1725 Family stress, 387–396 Ferrous sulfate, 1725 acute stress, 391–393 Fetal alcohol syndrome, 237 brief therapy, 394–395 Fetal assessment, 148–149 chronic stress, 392–393 Fetal growth, 145 cognitive behavioral therapy, 395 Fetal growth restriction, 219 counseling strategies for patients and families, Fetal heart monitoring (FHM), 148 393–394 Fetal hypoxia, 185, 189 crisis and adaptation, 390–391 Fetal macrosomia, 159 developmental and multigenerational, 390 Fetal stage, 17 family psychoeducation, 395–396 fundal height measurements, 17 family systems theory, 388–389 gestational diabetes, 17 health effects, 391–393 Fetal surveillance, 158 intergenerational approach, 396 Fetal tachycardia, 185 mindfulness, 395 Fetomaternal transfusion, 224 motivational interviewing, 394 Fetomaternal hemorrhage, 197 treatment approaches, 394–396 Fexofenadine, 896 Family systems theory, 388–389 Fiber, 105 Family therapy, 456 Fibrates, 1645 Family tree, 41, 43 Fibrinolysis, 842–843 Family violence, 45 Fibroadenomas, 1420 Fasciotomy, 1553 Fibrocystic changes, 1420 Fast and slow twitch fiber, 1507 Fibromuscular dysplasia, 839 Fat necrosis, 1421 Fibromyalgia, 1545–1550 Fat pad atrophy, 1510 Fibromyalgia Impact Questionnaire, 1548 Fatigue, 143, 452, 502, 505, 719–723, 726 Fibrosis, 1120 Fats, 105 Fibrositis, 1545 FDA approved bipolar disorder treatments, 435 Fibrous cortical defect, 1557 Fear, 412, 414 Fibula fracture, 1512 1832 Index

Fidaxomicin, 1147 Folate supplementation, 142 Fifth disease, 247 Folic acid, 16 Fifth edition of the Diagnostic and Statistical Manual of deficiency, 1696–1697 Mental Disorders (DSM–5), 773 prophylaxis, 75, 84 Filoviridae, 570 Folie à deux, 1598 Final menstrual period (FMP), 1383 Folinic acid, 565 Finasteride, 1632 Folliculitis, 673, 1587–1588 Fine-needle aspiration (FNA), 1414 decalvans, 1631 Fine needle aspiration and cytology (FNAC), 1681 Follow-up contact, 446 Finger Fondaparinux, 1046, 1048 distal tip fractures, 1484 Food allergy, 1237–1238 middle and proximal phalangeal fractures, 1484 Food and drug administration (FDA), 445, 704 First seizure, 836 Foot fracture, 1512 First trimester, 142–144 Forceps, 187–188 Fish-eye disease, 1639 Foreign bodies, 957–958 Fish hook removal Foreign object, 958 advance and cut technique, 662 Fourth heart sound, 1004 hook depression and string pull, 661–662 Fractional excretion of sodium, 1283 needle cover technique, 662 Fracture and treatment recommendations, 1492 prevention, 663 Fracture management, 681 principles, 660–661 Fracture prevention, 1491 retrograde pull, 661 Fracture Risk Assessment tool (FRAX), 1387, 1687 Fish oil, 105 Fragility fracture, 1387 Fistula plug, 1188 Fragmented care, 94 Fistulas, 1363–1364 Frailty, 305–308 Fistulectomy, 1187 Frank breech, 179 Fistulotomy, 1187 Fredrickson’s classification, 1639 Fit for Duty (FFD) examinations, 592–593 Free text, 1765 Fitness, 21 Freiberg disease, 285 Five A’s construct, 109 Frequent/premature atrial contractions (PACs), 995–996 Fixed drug eruption, 1579 Frontal headache, 819 Fixed-dose schedule, 762 Frontotemporal dementia, 341 5-year survival, 1106 Frostbite and non-freezing cold injuries (NFCI), 599 Flexible flatfoot, 284 Frozen shoulder, 1477 Flexible sigmoidoscopy, 1200 Fulguration, 1318 Flex sig, 1205 Full thickness burn, 656–658 Fluid disorders Functional Assessment Staging Scale (FAST), 799 potassium (See Potassium disorders) Functional incontinence, 321 sodium (See Sodium disorders) Functional neurological symptom disorder, 453 volume depletion, 1253–1255 Functional somatic syndromes (FSS), 453 volume excess, 1255–1256 Fungal infections, 1631 Fluid resuscitation, 658 Furazolidone, 570 Flunarizine, 853 Furuncles (boils), 1587–1588 Fluorescein staining, 894 Fluorescent treponemal antibody absorbed (FTA-ABS) tests, 535 G Fluoride, 75 Gabapentin, 767, 857, 1391 Fluoropyrimidine/oxaliplatin, 1207 Galactorrhea, 1419, 1702–1703 Fluoroquinolone, 892 Galactosemia, 222, 231 Fluoroquinolones, 1124, 1303 Gallbladder disease, 1389 Fluoxetine (Prozac), 263, 853, 858 Gallstones, 1158 FOBT/FIT, 1205 Gamekeeper’s thumb, 1486–1487 Focal epileptic seizures, 825 Gamma aminobutyric acid, 755 Focal segmental glomerulosclerosis, 1279–1280 γγ-glutamyltransferase, 1167 Focal seizures, 826–829 Ganglion cysts, 1482, 1553 Focused assessment with sonography in trauma (FAST), Gardner syndrome, 1554 1218 Gardnerella vaginalis, 1353 Folate deficiency, 1730–1731 Gardner’s syndrome, 1617 Index 1833

Garlic, 1646 Giant cell arteritis (GCA\; temporal arteritis), GAS Tonsillopharyngitis, 523 1539–1540 Gastric banding, 704 Giant cell tumors, 1554–1555 Gastric cancer, 1138 Giant papillary conjunctivitis, 895 Gastric lavage, 617 Giardia intestinalis, 250 Gastritis/gastropathy, 1137 Giardia lamblia, 569, 1142 Gastrocnemius and soleus, 1505 Giemsa staining, 894 Gastrocnemius-semimembranosus bursa, 1502 Gingivitis, 938–939 Gastroenteritis, 1234 Glasgow coma scale (GCS), 845 Gastroesophageal reflux disease (GERD) Glass test, 1302 diagnosis, 1133 Glaucomas, 923–924 management, 1133–1134 Gleason score, 1307, 1309 pharmacologic treatment of, 1134 Glenohumeral disorders symptom of, 1133 adhesive capsulitis, 1477 Gastrointestinal disorders, 461 labral injuries, 1477 Gastrointestinal infections, 250–252 osteoarthritis, 1477 Gastrointestinal symptoms, 726 osteonecrosis, 1477–1478 GBS colonization, 184 GLIF, 1765 GELLO, 1765 Globe injuries, 907 Generalized anxiety disorder (GAD), 414–415 Globe rupture, 910 7-item scale (GAD–7), 417 Glomerulonephritis, 1276–1278 Generalized pain, 1547 Glossitis, 941 Generalized seizures, 825–826 Glowing, 145 absence seizures, 825 Glucagon like peptide–1 (GLP–1), 1664–1665 atonic seizures, 826 Glucocorticoids, 1125, 1552 GTC seizures, 825–826 Glucosamine, 1520 myoclonus, 826 Glucotoxicity, 1651 Generalized Tonic-Clonic (GTC) seizures, 825–826 Gluteal insertional tendinopathy, 1496 Genes, 206 Gluteus medius, 1496 Genetic, 701 Glycated hemoglobin, 158 Genetic counselors, 214 Glycemic control, 1652 Genetic Information Nondiscrimination Act (GINA), 215 type 1 DM, 1658–1659 Genetic mutations, 1160, 1281 type 2 DM, 1659–1666 Genetic pattern of inheritance, 207 Gold standard, 1204 Genetic predisposition, 1546 Golden hour-maternal infant bonding, 194 Genetic risk reduction, 214 Gomco clamp, 1315 Genetic susceptibility, 1105 Gonadarche, 1706 Genetic syndromes, 208 Gonorrhea, 83, 88, 528–531 Genetic syndromes/developmental delay, 287 Goodsall’s rule, 1187 Genetic testing, 209–212 Gout, 1713–1714 Geneva criteria, 1043 Gracilis muscle, 1503 Genital herpes, 539–541, 1591 Graded exercise therapy (GET), 721 simplex, 156 Grady Memorial Hospital Interpregnancy Care Genital warts, 537–539, 1365–1367 Program, 137 Genito-pelvic pain/penetration disorder, 750 Grand mal, 825 Genitourinary syndrome of menopause (GSM), 1385 Granulomatosis with polyangiitis, 1277 Genogram, 41–44 Graves’ disease Genomic profiling, 1105 diagnosis, 1673 Genu valgus, 280–281 follow-up, 1674–1675 Genu varus, 279–280 signs and symptoms, 1673 Geographic information systems (GIS), 1767 treatment of, 1673–1674 Geriatrics, 106 Greater trochanteric pain syndrome (GTPS), German measles, 247 1496–1497 Gestational diabetes, 17 Greenstick fractures, 272 Gestational diabetes mellitus (GDM), 158 Grey Turner’s sign, 1158 Gestational weight gain, 143 Grief and depression, 801 Gestrinone, 1417 Group A streptococcal pharyngitis (GAS), 243 GI illness, 121 Group A streptococci, 1586 1834 Index

Group A streptococcus pharyngitis, 245 Health information technology, 1766 Group B Streptococcus, 181, 184 Health Insurance Portability and Accountability Act Group therapy, 765 (HIPAA), 1766 Growing pains, 275 Health insurance system, 1786 Grunting, 220 Health literacy, 94–95 Guanabenz, 970 Health maintenance, 74 Guanfacine, 970 Health maintenance organizations (HMOs), 712 Guarding, 1212 Health outcomes, 1787 Guggulipid, 1646 Health risk assessment, 62 Guided imagery, 1776 Health-care associated pneumonia (HCAP), 1086 Guidelines, 94 Healthcare-associated infections, 558 Guidelines, adults, 101 Healthcare industry, 1790 Guillain-Barre syndrome (GBS), 503, 862, 868 Healthcare organizations, 1789 Gummas, 534 Healthcare reform, 1789 Gustatory rhinitis, 1238 Healthcare system, 1786 Guttate psoriasis, 1569 Healthcare workforce, 1786 Gynecomastia, 1422–1423, 1703 Health-risk behaviors, 83 Healthy People 2020, 71–72 Hearing aids, 949 H Hearing impairment, 948 H2 breath test, 1239 Hearing loss, 600–601, 950–951, 958 HACEK group, 1055 Hearing protection, 949 Haemophilus influenzae, 242, 245, 511 Heart failure (HF), 1054–1055, 1057, 1060–1061, 1063, Half-buried mattress suture, 642–643 1066 Halitosis, 941–942 acute heart failure syndrome, 1025–1026 Hallucinogens, 781–782 B-type natriuretic peptide (BNP), 1018–1019 Halo nevi, 1605 causes, 1016 Haloperidol, 858 cardiac imaging, 1020 Hamilton Anxiety Rating Scale (HAM-A), 416 chest radiograph, 1019–1020 Hand-foot-mouth disease (HFMD), 248, 1592 classification and staging, 1016–1017 Hands, 1516 counseling and self-management, 1026 arthritis of the thumb, 1483 definition, 1015 metacarpal fractures, 1482–1484 electrocardiography (ECG), 1019 Hantavirus, 574 epidemiology, 1015–1016 Haptoglobin, 1285 evaluation and diagnosis, 1017–1020 Harvest mite, 1598 history and physical exam, 1017–1018 Hashimoto’s thyroiditis laboratory and imaging, 1018 diagnosis, 1679 with preserved ejection fraction, 1024–1025 signs and symptoms, 1679 with reduced ejection fraction, 1020 treatment, 1679 prevention, 1026 HBV serologies, 1170 treatment, 1020–1025 HDL-P, 1638 Heart murmurs, 1004–1005 Head lice, 1596 Heart-sink condition, 809 Headaches, 726 Heart sink patients, 712 approach to patient, 809 Heat injury, 597 consultation, 809 athletes, 597 classification, 807 nonathletic, 597 cluster, 817 treatment, 598 definition, 807 Heat urticaria, 1577 diagnosis, 809–812 Heavy menstrual bleeding, 1371, 1376–1377 epidemiology and impact, 807–808 Heavy metal poisoning, 1283 follow-up, 813 Heel spur, 1509 management plan, 812–813 Helminths, 1143 medication overuse, 819–820 Hemagglutinin (H), 511 migraine, 813–816 Hemangioma, 1612–1613 tension-type, 818–819 Hemarthrosis, 1504 HEADSSS assessment, 297 Hematocrit (Hct), 1719 Health care proxy, 802–803 Hematologic problems, 956 Health care reform, 46 Hematoma, 845 Index 1835

Hematuria, 1281, 1289, 1326, 1328 Herniotomy, 1225 Hemochromatosis, 1748–1749 Herpes, 563, 863 Hemodynamic variables, 557 Herpes gladiatorum, 1590 Hemoglobin A1c (HbA1c), 1652 Herpes keratitis, 898–899 Hemoglobin E, 1726 Herpes simplex, 1590–1591 Hemoglobinopathies, 672–673 labialis, 1591 Hemolysis, 1727 meningitis, 875 Hemolysis-elevated liver enzymes-low platelet count virus, 892, 898 (HELLP), 154 Herpes zoster (shingles), 248, 867, 1591–1592 Hemolytic anemia, 1731 ophthalmicus, 892 Hemolytic-uremic syndrome (HUS), 1235, 1740 virus, 892 Hemophilia, 845 Herpesvirus, 501 Hemophilia A, 1736–1737 Herpetic whitlow, 1590 Hemophilia B, 1737–1738 Heterophile antibody test, 502 Hemorrhage, 180 HHV8, 1611 Hemorrhagic conjunctivitis, 892 Hidradenitis suppurativa, 1573–1574, 1588–1589 Hemorrhagic fever with renal syndrome (HFRS), 575 background, 1194 Hemorrhoidectomy, 1184 diagnosis, 1194 Hemorrhoids, 145 treatment, 1194 background, 1182 High blood pressure, 727 classification, 1182 High-dose vitamin A supplementation, 1105 diagnosis, 1182–1183 Highly active antiretroviral therapy (HAART), 225, 548, epidemiology, 1182 1176 examination, 1183 High sensitivity CRP, 1641 history, 1182 Hip, 1516–1517 in-hospital surgery, 1184 Hip dislocations, 1492–1494 office procedures, 1183–1184 Hip fractures, 1490–1491 treatment, 1183 Hippocampal shrinkage, 343 Hemostasis, 639 Hirsutism, 1386, 1708 Henoch-Schönlein purpura (HSP), 1745 Histamine–2 receptor antagonists (H2RA), 1134 Heparin induced thrombocytopenia (HIT), 1046 Histone modification, 214 Hepatic encephalopathy, 858 Histoplasmosis Hepatitis A (HAV), 114, 155, 1168–1169 definition/background and epidemiology, 1094 clinical presentation and diagnosis, 1168 differential diagnosis, 1095 management, 1169 history, 1094–1095 prevention, 1169 laboratory and imaging, 1095 Hepatitis B, 84, 88, 1169–1171 medications, 1095 clinical presentation and diagnosis, 1169–1170 physical examination, 1095 Hepatitis B e antigen (HBeAg), 1170 special testing, 1095 Hepatitis B surface antigen (HBsAg), 1170 Histrionic personality disorder, 465 Hepatitis B vaccine, 114–115 HITECH Act, 1760–1761 Hepatitis B virus, screening, 1171 HIV, 83, 88, 155, 461 Hepatitis C, 155, 867, 1171–1174, 1626 Liver Disease, 1176 Hepatitis D, 1174 HIV/AIDS, 504 Hepatitis E virus, 1174 in IPV victims, 372 Hepatitis viral load PCR test, 1172 Hoarding disorder, 415 Hepato cellular carcinoma, 1171, 1176–1178 Hoarseness, 245, 954–956 Hepatomegaly, 502 Hofmann’sreflex, 1458 Hepcidin, 1724 Home blood glucose monitoring (HBGM), 1653 Heptavalent antitoxin, 1241 Home blood pressure monitoring, 971 Herald patch, 1579 Home canned items, 1241 Herbal remedies, 419 Home exercise program, 722 Herd immunity, 512 Home living, 333 Hereditary cancer syndromes, 213 Homeopathy, 1780 Hereditary hemochromatosis (HH), 1748–1749 Homeostasis, 556, 701 Hereditary hemorrhagic telangiectasia (HHT), 1741 Homocysteine, 1730 Hereditary neuropathies, 871 Honey, 1241 Hernioplasty, 1225 Hook depression and string pull, 661–662 Herniorrhaphy, 1225 Hordeolum, 917 1836 Index

Horizontal mattress suture, 642 Hypercapnia, 1078–1079 Hormonal chemotherapy, 1431 Hyperchromic RBC, 1721 Hormonal influences, 1396 Hyperchylomicronemia, 1639 Hormonal replacement, 1384 Hypercoaguable states, 1237 Hormone replacement therapy (HRT), 1427, 1690 Hyperemesis gravidarum, 159 Hormone therapy (HT), 1387 Hyperhomocysteinemia, 1042 Horner’s syndrome, 1107 Hyperinsulinemia, 1657 Hospice, 24, 345, 797–798 Hyperkeratosis, 1627 care, 1108 Hyperlipidemia, 1278, 1637 eligibility, 798 Hyperoxaluria, 1328, 1330 Hospital acquired pneumonia (HAP), 1086 Hyperparathyroidism, 858, 1330 Hospitalization, 555 Hyperpigmentation, 1625–1627 Hot flashes, 22, 1382, 1384 Hypersomnias, 726 Hot tub folliculitis, 1587 Hypertension, 88, 728, 964, 1282 HPV. See Human papilloma virus (HPV) Hypertensive disorders Human epidermal growth factor receptor–2, 1431 diagnosis, 169 Human Immunodeficiency Virus (HIV), 562, 867 epidemiology, 169 acute infection, 545 etiology, 169 aging patients, 551 management, 170 asymptomatic infection, 545 prevention, 169–170 blood and lymph, 549–550 Hypertensive emergency, 971 cardiac disease, 549 Hypertensive kidney disease, 1288 in children, 550–551 Hyperthyroidism, 159, 858 eye manifestations, 549 clinical presentation, 1671 GI tract and liver, 550 family impact, 1670–1671 HAART, 548–550 health risks, 1670 in women, 551 laboratory evaluation, 1671–1673 natural history, 544 prevalence of, 1670 patient evaluation, 547–548 Hypertonic saline, 846 PEP, 546 Hypertriglyceridemia, 1639 PrEP, 546 Hypertrophic cardiomyopathy (HCM), 670, 1010–1011 prophylaxis, 549 complications of, 1037 renal impairmen, 550 definition of, 1037, 1060 skin and mucosa, 549 diagnosis of, 1037 testing, 545 intervention, 1061–1062 wasting and fatigue, 549 management, 1038 Human papilloma virus (HPV), 528, 537, 539, 505, presentation and diagnosis, 1060–1061 943, 1365, 1400–1402, 1405, 1592 Hypertrophic scar, 1616 diagnosis, 1366 Hyperuricosuria, 1328, 1331 treatment, 1366 Hyperventilation, 846 Humerus, 1478 Hyphema, 907–909 Huntington’s disease, 853 Hypnosis, 767, 1782 Hyaluronic acid, 1520 Hypnotics, 726, 781 Hydralazine, 970 Hypoactive sexual desire disorder, 751 Hydralazine and nitrates, 1023 Hypoalbuminemia, 1278 Hydration, 953 Hypoalphalipoproteinemia, 1639 Hydrocele, 1321 Hypobetalipoproteinemia, 1639 Hydrocephalus, 846 Hypocalcemia, 858, 1709 Hydrochlorothiazide, 1331 Hypochondriasis, 450 Hydronephrosis, 1329 Hypochromic RBC, 1721 Hydroxychloroquine, 1126 Hypocitraturia, 1328, 1331 Hymenoptera stings, 609 Hypoglycemia, 223, 858, 1659, 1711–1713 clinical presentation, 609 Hypoglycemic agents, 858 management, 609 Hypogonadism, 1707 prevention, 609 Hypokalemia, 462 Hyperactivity and inattention, 475 Hypolipidemia, 1637 Hyperaldosteronism, 1712 Hypomagnesemia, 858 Hyperbilirubinemia, 221 Hyponatremia, 567, 858, 1705, 1711 Hypercalcemia, 1557, 1709–1711 Hypoperfusion, 556 Index 1837

Hypopigmentation, 1624–1625 Implanon&circled, 1341 Hypopigmented macules, 1624 Implantable cardiac defibrillators (ICD), 1024, 1038, Hypopituitarism, 1703–1704 1060, 1062 Hypothalamic-pituitary-adrenal (HPA) axis Implantable devices, 1024 dysfunction, 1547 The, IMPLICIT, Network, 137 Hypothermia, 598 Impulsivity, 444 Hypothyroidism, 159 Inaccurate dating, 182 clinical presentation, 1677 Inactivated influenza vaccine, 511 family issues, 1677 Incentive spirometry, 1122 health risks, 1676 Incidence, invasive breast carcinoma, 1425 laboratory evaluation, 1677 Incision and drainage, 1364 treatment of, 1677 Income, 700 Hypotonia, 858 Inconclusive, blood, cultures, 556 Hypoxemia, 1112 Incontinence, 344 Hypoxia, 729 Independent living facilities, 312–313 Hypsarrhythmia, 828 Indigestion, 1160 Hysterotomy, 178 Indirect fluorescent antibody (IFA), 564, 567 Individual therapy, 765 Individual/group therapy, 456 I Indoor air pollution, 1104 ICD–10-CM, 1765 Indoor air quality (IAQ), 592 Ictal cry, 825 Induction of labor, 178 Ideation, 443 Infancy, 17–18 Idiopathic hypercalciuria, 1328 Infant diet, 231 Idiopathic pancreatitis, 1160 Infantile aka Strawberry hemangioma, 1612 Idiopathic Parkinson’s disease (IPD), 851–856, 858 Infantile SD, 1567 Idiopathic postprandial syndrome, 1712 Infantile spasms, 828 Idiopathic scoliosis, 276 Infected droplets, 515 Idiopathic thrombocytopenic purpura (ITP), 1739 Infected stone, 1329 IDL-P, 1638 Infection, 721 IgE antibodies, 565 Infection-induced organ dysfunction, 556 IgG antibodies, 564 Infections, 1483 IgM antibodies to the viral core antigen dorsal hand infections, 1483 (IgM anti-HBc), 1170 palmar space infections, 1483 Iliotibial band syndrome (ITBS), 688–690 Infectious Disease Society of America (IDSA), Illicit drug misuse, 78 242, 520 Illness anxiety disorder, 453, 455 Infectious endocarditis (IE), 1055 Imbalance, 702 definition of, 1056–1057 Imiquimod, 538, 1592, 1604 differential diagnosis of, 1056 Immigrants, IPV, 372 intervention, 1056–1060 Immune complex mediated glomerular disease, prevention of, 1060 1276 Infectious mononucleosis (IM), 245, 501 Immune complex mediated glomerulonephritis, Infectious pathogens, 514 1277 Infectious proctitis Immune system, 452 background, 1192 Immunization, 74–75, 83–84 diagnosis, 1192 Immunocompetent, 562 treatment, 1192–1194 Immunocompromise, 226 Inferior vena cava filters (IVCs), 846, 1048 Immunocompromised patients, 556 Infertility, 20, 1447, 1703 Immunodeficient, 562 Inflammation, 917 Immunoglobulin A nephropathy, 1276 Influenza, 84, 511–513, 1081 Immunoglobulin G, 563 Informaticians, 1768 Immunoglobulin M (IgM), 1169 Information mastery, 53–55 antibodies, 564 Information systems, 1759, 1767–1768 Immunosuppressants, 1609 Informed consent, 794 Immunotherapy, 486, 1079 Infrared photocoagulation, 1184 Immuonsuppressed KS, 1612 Ingestions of foreign bodies, 659–660 Impaired memory/concentration, 726 Ingrown toenails, 1628 Impetigo, 673, 1586 Inguinal hernia, 1322 1838 Index

Inguinal hernia (cont.) Intersphincteric tract, 1187 anatomy, 1223 Interstitial cystitis, 1443 background, 1226–1227 Interstitial lung diseases (ILDs) complications, 1226 cor pulmonale, 1121 diagnosis and complications, 1224–1225 corticosteroids, 1121 differential diagnosis, 1225 dyspnea on exertion, 1120 treatment, 1225–1226 etiologies of, 1120 types, 1224 family and community issues, 1121 Inhalants, 782 honeycomb pattern, 1121 Inherited coagulopathies, 1042 pirfenidone, 1121 Injectable anesthetics, 635 Interventional pain management, 1552 Injectable contraceptives, 1341–1342 Intervertebral disc herniation, 1461 Injuries Intestinal nematode, 568 barotrauma, 653–656 Intimate partner violence (IPV), 89, 367–376 burns, 656–658 children, 371 causes of, 651 consequences, 369–370 drowning and submersion, 651–653 cycle of abuse, 368 fish hook removal, 660–663 HIV in, 372 swallowed foreign body, 659–660 Lesbian, Gay, Bisexual, Transsexual, and Queer Inkpot lentigo, 1606 (LGBTQ), 370–371 Innovation, 1788–1789 management, 374–376 Insomnia, 726, 1385 pregnant women, 371 older adults, 726 prevalence, 367–368 women, 726 prevention, 373 Inspiratory stridor, 245 public health and economic issue, 372 Inspiratory whoop, 244 screening, 373–374 Institute for Health Care Improvement, 41 subtypes, 368–369 Institute of Medicine (IOM), 1767 teens, 371–372 Instrumental activities of daily living (IADL), 306 Intraaortic balloon pump counterpulsation (IABP), 1031 Insufficiency fractures, 1490 Intra-articular anesthesia, 1498 Insufficient milk, 198 Intra-cerebral hemorrhage (ICH), 838, 844–846 Insulin resistance and metabolic syndrome, 728 Intracranial hemorrhage, 225 Insulin-like growth factor (IGF), 1713 Intracranial lesions, 875 Integrative medicine (IM) Intracranial pressure (ICP), 845 definition, 1771 Intradermal running closure, 641 therapies, 1772 Intraductal papillary mucinous neoplasms treatments, 1773 (IPMN), 1162 Intellectual disabilities, 413 Intraductal papilloma, 1421 Intensity, 703 Intralesional triamcinolone, 1616 Intensive outpatient programs, 764 Intranasal glucocorticoids, 521 Interactional group psychotherapy, 764 Intrapartum analgesia, 150 Interconception care, 128 Intrapartum antibiotic prophylaxis, 184 Interdigital nerve compression, 1511 Intrapartum fever, 184, 219 Interdigital neuralgia, 865 Intrapartum GBS, 184 Interferon, 1171 Intrauterine devices, 1339–1340 Intermenstrual abnormal uterine bleeding, 1371 Intravaginal torsion, 1312 Intermittent alcohol abuse, 757 Intravenous drug users (IVDUs), 1055 Intermittent allergic rhinitis, 482 Intravenous hydration, 1159 Internal ring occlusion test, 1225 Intravenous immunoglobulin, 868, 1066 International Prostate Symptom Score, 1296 Intravenous oxytocin, 151 International Registry of Aortic Dissection (IRAD), Intravenous urography, 1328 1032–1033 Intrinsic and extrinsic risk factors, 1491 International traveler Intrinsic sphincteric deficiency, 320 post-trip consultation, 120–122 Invagination test, 1225 pretrip consultation (See Pretrip consultation) Invasive breast carcinoma, 1425 Internet, 1766 Inverse psoriasis, 1569 Interoperability, 1763, 1766 Iodine, 131, 1674 Interpreters, medical, 35–36 Ionizing radiation, 1104 Intersection syndrome, 1482 Ipecac, 617–618 Index 1839

IPMN. See Intraductal papillary mucinous Juvenile idiopathic arthritis (JIA), 1531–1532 neoplasms (IPMN) Juvenile Myoclonic Epilepsy (JME), 826 IPV. See Intimate partner violence (IPV) – Iritis, 897 898 K Iron, 105–106 Kaposi’s sarcoma (KS), 1611–1612 deficiency, 1697–1698 Kawasaki disease (KD), 249–250 deficiency anemia, 1720, 1723–1726 Kayser-Fleischer rings, 853 deficiency anemia (IDA), 80, 158 Keloid, 1616 dextran, 1726 Keratin plug, 1610, 1627 supplementation, 1726, 1728 Keratinolytic medications, 1627 Irregular bleeding, 1376 Keratoacanthoma, 1610–1611 Irreversible ischemic damage, 1313 Keratoconjunctivitis, 892 Irritability and aggression, 475 Kerion, 1593 Irritable bowel syndrome (IBS), 1149–1150, 1444 Kernicterus, 221 Irritant contact dermatitis”, 1574 Ketamine, 638, 1552 Ischemic bowel syndrome (IBS), 1236, 1239 Kick counts, 148 Ischemic colitis, 1237 Kidney biopsy, 1280 Ischemic heart disease (IHD) Kleinman’s explanatory model, 713 coronary angiography, 976 Klinefelter syndrome, 1707 definition, 973 Knee, 1516 electrocardiogram and biomarkers, 975 Knee bursitis, 1503 history, 974–975 Knee dislocation, 1505 management, 976–979 Knee fractures and dislocations, 1504–1505 physical exam, 975 Knee ligament sprain/tears, 690–691 pretest probability, 974 Koebner reaction, 1575 principles, 973 KOH, 1352, 1628 stress testing and cardiac imaging, Kohler disease, 285 975–976 Korsakoff’s syndrome, 870 Ischemic stroke, 838, 841–844 Kostmann syndrome, 1747 Isoenergetic balanced diet, 703 KRAS, 1203 Isotonic sodium bicarbonate, 1284 Isotretinoin, 1572 I-statement, 442 L Itopride, 853 Labetalol, 157 Ivermectin, 1143 Labor IVIG, 868 stage one, 149 Ixodes pacificus, 572 stage three, 149 Ixodes ricerus, 572 stage two, 149 Ixodes scapularis, 572 support during, 149–150 Laboratory testing, 721 Labor dystocia, 183–184 J Labral injuries, 1477 Japanese encephalitis (JE) vaccination, 116 Lacrimal system, 918–919 Jarisch-Herxheimer, 568 Lactase, 1238–1239 JASON group, 1762 Lactate dehydrogenase, 1556–1557 Jaundice, 80, 154, 221–223, 1163 Lactation-amenorrhea method (LAM), 198, 1347 Jersey finger, 688 Lactation-safe medications, 18 Jet lag and shift work disorders, 730 Lactic dehydrogenase, 1285 Jock itch, 1593 Lactobacilli, 1352–1353 Jogger’s toe, 674 Lactoferin, 1234 Joining, 45 Lactose, 1239 Joint National Committee 8 (JNC, 8), 966 Lactose intolerance, 1238–1239 Joint pain Lactose tolerance test, 1239 medical history, 1526 Lacunar strokes, 838 physical examination, 1526–1527 Lamaze-type breathing exercises, 813 Joint Principles, 1802 Landau Kleffner syndrome, 829 Joint swelling, 1517 Language development, 19 Jugular venous distention, 1054 Laparoscopic cholecystectomy, 1222–1223 Jump sign, 1551 Laparoscopical resection, CRC, 1207 1840 Index

Large cell carcinoma, 1106 Length of therapy, 1048 Large for gestational age, 219 Lennox Gastaut Syndrome (LGS), 829 Laryngitis, 510–511 Lentigo maligna, 1606 Laryngoscopy, 955–956 Lentigo maligna melanoma, 1607 Lasègue’s sign, 1458 Leprosy, 867 Laser iridotomy, 900 Leptin, adiponectin, 702 Late disseminated Disease, 573 Lesbian, Gay, Bisexual, Transsexual, and Queer Late latent syphilis, 536 (LGBTQ), IPV, 370 Late postmenopause, 1383 Leser-Trelat sign, 1602 Late preterm infants, 218–219 Leukemias, 1752–1754 Late syphilis, 534 Leukocytosis, 575 Latent autoimmune diabetes of adulthood (LADA), 1650 Leukoplakia, 1618 Latent syphilis, 535 Levels of care, 333–334 Latent syphilis of unknown duration, 536 Levodopa, 851, 854 Lateral collateral ligament (LCL), 690 Levodopa/Carbidopa, 854 Lateral epicondylitis, 1479 Levofloxacin, 534 Lateral epicondylitis (Tennis elbow), 686 Levonorgestrel, 1339 Lateral internal sphincterotomy (open or closed), 1186 Levosulpiride, 853 Lateral plantar branch, 1509 Lewy body dementia, 341 LDL-P, 1638 Lice, 1596 Lead, 77 Lichen planus, 940, 1363, 1626 Lead poisoning, 292–293 Lichen sclerosis, 1363 Learning disabilities, 19 Lid swelling, 890 Learning disorders (LD), 258 Life expectancy, 22–23 academic accommodations, 259 Lifestyle, 77, 100 behavioral components, 259 Lifetime risk, 1105, 1426 cognitive components, 259 Ligasure procedure, 1184 cognitive-behavioral treatments (CBT), 258 Light’s Criteria Rule, 1119 emotional regulation components, 259 Limb salvage, 1554 impairment in reading, 258 Lipase, 1158, 1160 mathematics, 258 Lipemia retinalis, 1640 prevalence rates, 258 Lipid screening, 82 symptoms, 258 Lipid targets, 1642 written expression, 258 Lipoma, 1616–1617 Learning Health System Initiative, 1767–1768 Lipoprotein(s), 1637–1638 Lecithin Cholesterol Acyltransferase (LCAT) deficiency, Lipoprotein (a), 1639 1639 Lipotoxicity, 1661 Left lateral decubitus, 1206 Listeria monocytogenes, 1235 Left ventricular outflow tract (LVOT) obstruction, 1060 Listeriosis, 1234 Legg-Calve-Perthes disease, 283 Lithium, 465, 853, 858 Legionnaire’s disease Live attenuated influenza vaccine, 511 definition/background, 1097 Liver biopsy, 1173 differential diagnosis, 1098 Living wills, 802–803 epidemiology, 1097 Lobar hemorrhage, 845 family and community issues, 1098 Lobe of the cortex, 827 history and physical examination, 1097 Lobular carcinoma in-situ, 1425 laboratory and imaging, 1098 Local anesthesia medications, 1098 injectable anesthesia, 635–636 prevention, 1098 topical agents, 635 special testing, 1098 Local twitch response, 1551 Leiomyoma Logic coding systems, 1765 classification, 1395–1396 Logical Observations, Identifiers, Names and definition, 1395 Codes (LOINC®) system, 1765 ® diagnosis, 1396 LOINC , 1765 epidemiology, 1395 Lomitapide, 1646 prevention, 1397 Long-acting reversible contraception (LARC), 1338 risk factors, 1396 Longitudinal arch, 1509 treatment, 1396–1397 Long-term anticoagulation, 1048 Leiomyosarcoma, 504 Loratadine, 896 Index 1841

Lorazepam, 761 Malaria prophylaxis, 118–119 Low back pain, 1455 Malarone, 118 Low body weight, 460 Malassezia furfur, 1596, 1625 Low-carbohydrate, 703 Male breast cancer, 1426 Low-dose computed tomography (CT) screening, 1105 Male circumcision Low frequency shock wave therapy, 1497 adverse events, 1315 Low-molecular weight heparin (LMWH), 1046, 1048 bleeding, 1315 Low transverse incision, 178 complications, 1314 Lower respiratory tract infection, 514 health benefits, 1314 Lower urinary tract symptoms, 1294 neonatal period, 1314 Lp(a), 1641, 1643, 1645 prevalence, 1314 Lp-PLA2, 1641 techniques, 1315 Lumbar discectomy, 1466 Malfunction, 705 Lumbar drainage, 847 Malignancies, 461, 1367 Lumbar imaging, 1459 Mallet finger, 687–688 Lumbar median branch neurotomy (LMBN), 1462 Mallet finger injuries, 1485–1486 Lumbosacral plexitis, 866 Malnutrition, 460, 1698–1699 Lung cancer, 88 Malpresentation, 189 classifications, 1106 Mammalian bites, 606 clinical presentation of, 1106–1107 clinical presentation, 606 diagnostic approach, 1107 diagnosis, 606 general principles, 1103 established infections, 607 incidence of, 1103 family and community issues, 608 lung nodules, 1107 management, 606–607 non-small cell lung cancer, 1107–1108 prevention, 607 primary prevention, 1104–1105 prophylactic antibiotics, 607 secondary prevention, 1105–1106 rabies prophylaxis, 607 small cell lung cancer, 1108 Mammography, 87, 1427 treatment, 1108–1109 Managing populations, 1785 Lung carcinogenesis, 1105 Maneuvers, 186–187 Lung scintigraphy, 157 Mania, 434 Lung transplantation, 1069 Manic episode, DSM, 5 criteria, 427 Lupus nephritis, 1276–1277 Mannitol, 846, 1240 Lyme Disease (LD), 572, 867–868 Manual aspiration, 1117 Lymphadenopathy, 563 Manual medicine, 1776 Lymphedema, 1432 Manual rotation, 188 Lymphoma, 1283 MAO B inhibitors, 855 Lynch syndrome. See Nonpolyposis colorectal cancer Marburg, 570 (HNPCC) Marijuana, 780–781 Marine animal stings, 611 Marine poisoning, 1240 M Marsupialization, 1187, 1365 Macrocytic anemia, 1720, 1724, 1729–1731 Mass effect, 846 Macrocytosis, 1729 Massage therapy, 1778–1783 Macrolide, 1124 Mastitis, 1418 Macrovascular disease, 1657 causes, 197 Macular & maculopapular exanthems, 247 Matchbox sign, 1598 Macular degeneration, 921–922 Maternal-to-child transmission, 1174 Magnetic resonance angiography (MRA), 841, 1046 Maternity care, 142 Magnetic resonance imaging (MRI), 1158, 1162, 1164, Maudsley Method, 461 1428, 1459, 1554 McKenzie method, 1465 Magnets, 659 MCN. See Mucinous cystic neoplasms (MCN) Magpie trial, 170 Meal replacement plan, 703 Main duct, 1163 Meals on Wheels, 330 Maintenance therapy, 1136 Mean corpuscular hemoglobin (MCH), 1721 Major depressive disorder (MDD), 83, 425 Mean corpuscular hemoglobin concentration (MCHC) Malabsorption syndromes, 704 1721 Maladaptive response, 456 Mean corpuscular volume (MCV), 1721, 1725 Malaise, 1160 Measles, 156, 247 1842 Index

Meatball and spaghetti, 1596 non-infectious etiology, 874 Mebendazole, 252, 568, 1143 non-infectious meningitis, 876 Mechanical ventilation, 1112, 1241 physical exam, 874 Meconium stained amniotic fluid, 185–186 positive predictive value, 874 Media calcaneal branch, 1509 presentation of, 874 Medial collateral ligament (MCL), 690 rate of, 874 Medial patellofemoral ligament tear, 1505 sensitivity and specificity, 874 Medical Eligibility Criteria for Contraceptive Use (MEC), Meningococcal vaccine (MCV4), 116 1336–1337 Meningococcemia, 249 Medical Home Meningovascular syphilis, 879 accreditation, 1802 Meniscal injuries, 1500–1502 certification, 1802 Meniscal repair, 1501 definition, 1793–1794 Meniscal tests, 1500 family medicine, 1796–1798 Meniscus tear, 691–692 history, 1794 Menopausal transition, 1382–1383, 1385–1386 practice transformation, 1802–1803 Menopause, 21, 1371, 1382, 1384 principles and characteristics, 1794–1796 Menorrhagia, 1398 recognition, 1802 Menstrual disorders Medical imaging, 599 abnormal uterine bleeding, 1375–1379 Medical Subject Headings (MeSH), 1765 amenorrhea, 1371–1373 Medicare, 314–316 bleeding associated with contraceptive method, 1377 covered services, 314–316 dysmenorrhea, 1379 Part A, 314 female athlete triad, 1373–1374 Part B, 314 heavy menstrual bleeding, 1376–1377 Part C, 314 irregular bleeding, 1376 Part D, 314 polycystic ovary syndrome, 1377–1379 Medicare part B billings, 1760 severe acute bleeding, 1375 Medicare program, 22 Mental health, 443 Medicare wellness visit, 339 Mentally ill patients, primary care Medication(s), 954, 1213 behavioral symptoms, 403 Medication overuse headache (MOH), 819–820 counseling, 407–408 Medication reconciliation, 327 cultural, social/personality characteristics, 403 Meditation, 106–107, 419–420, 1775 definition/background, 401–402 Mediterranean diet, 1643 diagnosis, 403–404 Mediterranean style diet, 104–105 differential diagnosis, 406 Mediterranean-type diets, 703 epidemiology, 402–403 ® MEDLINE , 1765 family and community issues, 408 Medroxyprogesterone, 1399–1400 laboratory and imaging, 406 Medroxyprogesterone acetate (DMPA), 1341–1342 medications\immunizations and chemoprophylaxis, Mefloquine, 118 406–407 Megaloblastic anemia, 1729–1731 patient education and activation, 408 Melanocytes, 1624 physical examination, 405 Melanoma, 1606–1608 prevention, 408 Melatonin, 344, 730 referrals, 407 Memantine, 343 treatment, 406 Membranoproliferative glomerulonephritis, 1281 Meralgia paresthetica, 865 Membranous nephropathy, 1278–1280 MERS-CoV, 515 Memory loss, 1386 Mesalamine, 1155 Meningeal signs, 874 Mesenteric arterial thrombosis, 1236 Meningitis, 219, 503–504 Mesenteric venous thrombosis, 1237 cerebrospinal fluid examination, 875 Mesial Temporal Lobe Epilepsy (MTLE), 833 “chemical” meningitis, 876 Mesial Temporal Sclerosis (MTS), 830 chronic meningitis, 875–876 Mesothelioma, 1106 definition, 874 Meta-analysis, 456 herpes simplex meningitis, 875 Metabolic acidosis, 1264–1266 history, 874 Metabolic alkalosis, 1267 infectious agents, 874 Metabolic syndrome, 728, 1643 meningeal signs, 874 Metabolism, 701 mortality, 875 Metastatic bone pain, 801 Index 1843

Metastatic disease, 881 Modes of inheritance, 207 Metastatic malignant tumors, 1557 Modifiable risk factors, 838 Metatarsal pad, 1511 Modified cognitive behavioral therapy, 463 Metatarsalgia, 1510–1511 Mogen clamp, 1316 Metatarsus adductus, 278–279 Mogul’s palm, 674 Metathesaurus, 1765 Mohs surgery, 1609–1610 Metformin, 1288 Molecular genomic medicine, 205 Metformin therapy, 1661 Molecular testing, 210 Methadone, 800 Molluscum contagiosum, 893 Methicillin resistant Staphylococcus aureus (MRSA), 1589 Monoamine oxidase B (MAO B) inhibitors, 855 Methimazole, 159 Monoamine Oxidase Inhibitors, 431 Methotrexate, 1126 Monoclonal antibodies, 1108 Methyldopa, 970 Mononucleosis, 562 Methylmalonic acid (MMA), 1730 Montevideo units, 183 Methylphenidate (Ritalin), 858 Montreal Cognitive Assessment (MoCA), 339 Metoclopramide, 815, 853 Mood disorders. See Bipolar disorders; Depressive Metoclopramide (Reglan), 858 disorders Metoprolol, 857 Mood disturbance, 726 Metronidazole, 531–533, 570 Mood stabilizer, 853 Microalbuminuria, 1653 Moon facies, 1711 Microbiological investigations, 556 Moral authority, 710 Microbiology, rhinosinusitis, 520 Moraxella catarrhalis, 242, 245, 511 Microcytic anemia, 1720, 1722 Morbidity, 511 Microcytosis, 1726 Morning sickness, 143 Microscopic polyangitis, 1277 Mortality, 557, 875, 1426 Microvascular disease, 1284 Morton toe, 1511 Middle age, 21–22 Morton’s foot, 1511 Middle and proximal phalangeal fractures, 1484 Morton’s neuroma, 865, 1511, 1552 Middle ear barotrauma, 655 “Mosquitoes” bite, 610 Middle ear effusion (MEE), 244 Mother-to-child transmission, 225 Midfacial hypoplasia, 237 Motivational enhancement therapy, 765 Midshaft fractures, 1474 Motivational interviewing (MI), 109 Migraine, 160, 813–815 Motor delay, 290 Migraine prophylaxis, 160 Motor vehicular accidents, 728 Mild cognitive impairment (MCI), 340 MR arthrogram, 1495 Milnacipran, 1550 MRCP. See MRI employing magnetic resonance Mind-body-environment, 389–390 cholangiopancreatography (MRCP) Mind-body medicine, 1773–1776 MRI. See Magnetic resonance imaging (MRI) Mindfulness, 420 MRI, bowel obstruction, 1228 Mindfulness based stress reduction (MBSR), 1550 MRI employing magnetic resonance Mini-Cog, 339 cholangiopancreatography (MRCP), 1158, 1161 Minimal change disease (MCD), 1279–1280 MSTFCC, 1203 Mini-Mental Status Exam (MMSE), 335, 339 Mucinous cystic neoplasms (MCNs), 1162, 1163 Minority, 28, 31–32 Mucocele(s), 944, 1619 Minority groups, 723 Mucolytics, 522 Minoxidil, 970, 1632 Muddy brown granular casts, 1284 Mipomersen, 1646 Muffled heart sounds, 1054 ® Mirena , 1339 Mulder’s sign, 1511 Misoprostol, 178 Multiple myeloma (MM), 1462, 1752 Mitomycin, 1327 Multiple sclerosis (MS), 504, 858 Mitotic rate, 1607 corticosteroids, 884 Mitral stenosis, 1009 diagnostic criteria for, 883 Mitral valve prolapse, 1009 differential diagnosis, 883–884 Mitral valve regurgitation, 1007–1009 disease-modifying agents, 884 Mixed acid–base disturbance, 1268–1270 exacerbations, 884 Mixed episode, 442 fatigue, 884 Mixed incontinence, 321 incidence of, 882 Mobitz I, 997 neurogenic bladder, 884 Mobitz II, 997 pain, 884 1844 Index

Multiple sclerosis (MS) (cont.) Nasal irrigation, 243 presentation of, 882–883 Nasal packing, 957 primary-progressive MS, 884 Nasal saline irrigation, 521 relapsing-remitting and secondary-progressive MS, Nasopharynx, 956 884 Nateglinide, 1662 Multi-vitamins, 105 National Comprehensive Cancer Network, 1107 Mumps, 953, 1323 National Glycosylated Hemoglobin Standardization Murmur, 1055 Program (NGSP), 1652 Murmurs during pregnancy, 1011–1012 National Health and Nutrition Examination Survey Murmurs in athlete, 1012 (NHANES), 1699 Muscle relaxants, 789, 1465 National Institute of Occupational Safety and Health Mutations, 206, 1105 (NIOSH), 584 Myalgias, 512, 1643, 1646 National Institute on Drug Abuse (NIDA), 774 Mycobacterium avium complex (MAC) National Institutes of Health Stroke Scale (NIHSS), 840 definition/background, epidemiology, 1098–1099 National Library of Medicine, 1765 history and physical examination, 1099 National Lung Screening Trial (NLST), 1105 laboratory and imaging, 1099 2013 National Survey on Drug Use and Health (NSDUH), management, 1099 773 special testing, 1099 Native valves, 1057 Mycoplasma pneumonia Natural family planning (NFP), 1347 history and physical exam, 1089–1090 Natural products/herbal medicine, 1772–1773 laboratory and imaging, special testing, 1090 Naturopathy, 1781–1782 prevalence of, 1089 Nausea, 143 prevention, 1090 Nausea and vomiting, 801 treatment, 1090 Near term infants, 218 Myelodysplastic syndromes (MDS), 1729, 1752 Necrotizing fasciitis, 1589 Myelophthisic anemias, 1729 Needle aopneurotomy, 1553 Myiasis (botfly), 1599 Needle cover technique, 662 Myocardial dysfunction, 1060 Neisseria gonorrhoeae, 534, 890 Myocardial infarction (MI), 728, 973–975, 977, 1030, Neonatal anomalies, 226 1463 Neonatal circumcision. See Male circumcision Myocarditis, 503, 1063 Neonatal conjunctivitis, 894 etiologies of, 1064–1065 Neonatal sepsis, 184, 219 intervention, 1066 Neoplasms, 952 presentation and diagnosis, 1065–1066 Nephritic syndrome, 1276 Myoclonic absence seizures, 825 Nephrolithotomy, 1329 Myoclonic seizures, 826, 828 Nephrotic syndrome, 1278–1281 Myoclonus, 800 Nerve grafts, 1552 Myofascial pain syndrome, 1550 Neuraminidase (N), 511 Myopathy, 1643 Neuraminidase inhibitor, 513 Myositis ossificans, 1499 Neurocognitive disorder (NCD), 340 Neurocutaneous syndrome, 1625 Neurogenic bladder, 884 N Neurogenic bowel, 884 Nadolol, 857 Neurogenic claudication, 1052 Nail(s), 1628 Neurohypophysis, 1702 Nail-biting, 265 Neuroimaging, 812, 840 cognitive-behavioral treatments (CBT), 265 Neurologic exam, 1457 co-morbid psychological conditions, 265 Neurological sequelae, 879 medically, 265 Neuroma, 1552 stereotypical behaviors, 265 Neuromotor exercise, 101 Nail dystrophies, 674 Neuropathic agents, 329 Nail melanoma, 1607 Neuropathic pain, 800–801 Naltrexone, 765 Neuropathy, 1325 Narcissistic personality disorder, 465 Neuropsychiatric sequelae, 877 Narcolepsy, 730 Neurosyphilis, 340, 535–536 Narcotics, 1329 Neuroticism, 451 Nasal antihistamines, 485 Neutropenia Nasal endoscopy, 521 autoimmune neutropenia, 1747 Index 1845

classifications of, 1746 Nonsteroidal antiinflammatory drugs (NSAIDs), congenital neutropenia, 1747 818, 1049, 1054, 1329, 1464, 1519, 1529, 1550 drug-induced neutropenia, 1747 Nonstress test, 148 intrinsic defects, 1748 Nontraditional suicide risk factors, 446 isoimmune neutropenia, 1747 Nontreponemal tests, 535 nutritional neutropenia, 1748 Non-tuberculous mycobacteria (NTM), 1099 postinfectious neutropenia, 1747 Non-verbal strategies, 45 Nevus, 1604–1606 Noradrenergic antinociceptive pathway, 1550 Nevus spilus, 1605 Normal gait and alignment, 278 New York Heart Association’s (NYHA) classifications, Normal pressure hydrocephalus, 340 1016 Normative stressors, 387 Niacin, 1645 Normocytic anemia, 1720, 1723, 1727–1731 Nickel, 1575 The North Carolina Statewide Multivitamin Distribution Nicolski sign, 1582 Program, 137 Nicotine replacements, 108 Norwegian Scabies, 1597 Nifedipine, 157 Nose, 957–958 Nightmare(s), 413, 731 NSAIDs. See Nonsteroidal antiinflammatory drugs Nightmare disorder, 267–268 (NSAIDs) cognitively alert, 267 Nuchal translucency, 144 physiological symptoms, 268 Nucleic acid amplification test (NAAT), 528, 1093 prevalence rates, 267 Nucleic acid hybridization tests, 530 well-remembered dreams, 267 Nucleoside/nucleotide analogues (NUCs), 1171 NIH Chronic Prostatitis Symptom Index, 1303 Nulliparity, 182, 1398 Nimodipine, 847 Number needed to treat, 52 Nipple discharge, 1418, 1429 Nummular eczema, 1564 Nipple pain, 1417 Nurse-family partnership, 137 Nit comb, 1596 Nursemaid’s elbow, 1480 Nitazoxanide, 1143 Nutrition, 103–106, 329–331 Nitroglycerin, 979 Nutrition assessment, 104 N-methyl-D-aspartate, 755 Nutritional assessment, 331 NMR Lipoprofile, 1641 Nutritional deficiencies, 331, 706 N,N-diethyl-meta-toluamide (DEET), 119 Nutritional supplements, 722 Nodular anterior scleritis, 897 Nutritional support, 1159 ® Noise, 600–601, 951 NuvaRing , 1346 Non-alcoholic fatty liver disease (NAFLD), 1176 Non-aneurysmal SAH (NASAH), 846 Nonarteritic ischemic optic neuropathy, 1640 O Noncaseating granulomas, 1124 Obese, 699 Nondihydropyridine calcium channel blockers, 1024 Obesity, 40, 82, 88, 143, 161, 727, 1163, 1327, 1521, 1724 Non-gonococcal urethritis, 531 BMI, 700 Nonhemorrhoidal anorectal diseases, 1184–1186 cardiovascular risk factors, 700 Non-hormonal therapies, 1388 child abuse, 363 Non-infectious meningitis, 876 diets, 703 Non-megaloblastic anemia, 1731 exercise, 703–704 Non-modifiable risk factors, 838 homeostasis, 701 Non-nephrotic range proteinturia, 1281 imbalance, 702 Non-normative family stressors, 387 income, 700 Non-occlusive ischemia, 1237 lab testing, 702 Non-operative treatment, 1185 medications, 702 Non-ossifying fibroma, 1557 pharmacological management, 704 Non-pharmacologic management, 309 physical examination, 702 Nonpolyposis colorectal cancer (HNPCC), 1201 prevalence of, 699 Nonproliferative lesions, 1420 prevention, 706 Nonproliferative retinopathy, 1655 racial and socioeconomic disparity, 699 Non-resolving infiltrates, 1106 surgical treatment, 704 Non-scarring, 1630 treatment, 703 Nonseminoma, 1324–1325 Obesogenic, 702 Nonspecific low back pain, 1460 Obsessive-compulsive disorder (OCD), 412, 415, 450 Non-specific symptoms, 1547 Obsessive-compulsive personality disorder, 466 1846 Index

Obstetric complications, pregnancy Older drivers, 316, 334–335 ectopic pregnancy, 167–168 Olecranon bursitis, 1480 hypertensive disorders (see Hypertensive disorders) Oligomenorrhea, 1703 placenta previa, 171–172 Ondansetron, 855, 1144 preterm labor and delivery, 172–174 Onion peel, 1555 spontaneous abortion, 166–167 On-line reference, 1765 Obstetrical emergency, 186, 188 Onychomycosis, 1594, 1628 Obstructed hernias, 1225 Onychophagia, 265 Obstruction, 1200, 1284 Oocysts, 562 Obstructive sleep apnea (OSA), 727, 731, 966 Open-ended approach, 810 Occiput anterior presentations, 188 Open globe injuries, 910 Occult blood, 1234 Open hemorrhoidectomy, 1184 Occupational and Environmental Medicine (OEM), 582 Operative vaginal delivery, 187–188 Occupational carcinogen exposures, 1104 Ophthalmia neonatorum, 894 Occupational Health and Safety Administration, 584 Ophthalmic division, trigeminal nerve, 893 Occupational health care Ophthalmologist, 899–900 ADA, 584–585 Ophthalmology, 896–898 commercial driver medical examinations, 593 Opiates, 638 communication, 587 Opioid(s), 328–329, 778–779, 1465, 1520 comprehensive occupational health programs, 593 acute medical treatment, 779 documentation, 585 dependence/abuse, treatment of, 779–780 epidemiology, 583 discontinuation of, 795 FFD and return to work examinations, 592–593 effects, 779 FMLA, 585 indications/contraindications and risks of, 789–792 infections, 589 Opioid analgesics, 792 injuries, 588–589 Opioid equianalgesic table, 329 latex allergy, 589–590 Opioid toxicity, 800 medications and substances, 586 Opioid trial algorithm, 789 NIOSH, 584 Opportunistic infections, 1176 Occupational Health and Safety Administration, Oppositional defiant disorder (ODD), 260 584 anger/irate mood, 260 occupational history, 586 argues with others, 260 physical examination, 586 argumentative/defiant, 260 post hire, pre-placement examination, 592 cognitive-behavioral treatments (CBT), 261 psychosocial factors, 586–587 frequently loses temper, 260 return to work, 587–588 genders, 260 SBS, 590–592 medications, 262 systematic injury history, 585–586 prevalence rates, 260 worker’s compensation, 583–584 rates, 260 Occupational Safety and Health Act (OSH Act), Optic nerve disc edema, 922–923 584 Optic nerve injury, 911 Occupational therapy, 1520 Optical coherence tomography (OCT), 1655 Ocular emergency, 899 Opt-out HIV testing, 83 Ocular herpes, 1590 Oral antihistamines, 485 Ocular migraine, 921 Oral anti-leukotrienes, 486 Ocular rosacea, 1573 Oral cancer, 943–944, 1618 Odynophagia, 955 Oral decongestants, 485 Offenders, 358 Oral dissolution of cholelithiasis, 1223 Office evaluation, 1352 Oral hairy leukoplakia, 1618 Ohtahara syndrome, 827–828 Oral health, 291 Olanzapine, 853 Oral retinoids, 1572 Old age Oral steroids, 1625 advanced directives, 24 Oral sucrose, 1315 dementias, 23 Orange tonsils, 1640 falls, 24 Orbital infection, 919 osteoporosis, 24 Orchiectomy, 1325 sensory deficits, 23 Order sets, 1765 stages of grief, 23 Oregon Foundation for Reproductive Health, 137 urinary incontinence, 24 Organ transplantation, 562 Index 1847

Orgasmic disorder, 749–750 risk factors, 1406 Orthostatic hypotension, 324 staging/treatment, 1407–1408 Orthotic devices, 1627 Ovarian cysts, 1439 OSA. See Obstructive sleep apnea (OSA) Overactive bladder, 320 Oseltamivir, 512–513 Overdose, 445 Osgood-Schlatter disease, 274 Overflow incontinence, 321 Osteitis deformans, 1557 Overweight, 82, 88, 700 Osteoarthritis, 1460, 1477, 1516 Ovulation disorders, 1449 rheumatoid arthritis (RA) vs., 1531 Oxazepam, 761 Osteoblastoma, 1554 Oxcarbazepine, 863 Osteochondral defects, 1504 Oxybenzone, 1621 Osteochondritis dissecans, 274–275, 1504 Oxygenated glycerol triesters (OGT), 954 Osteochondroma, 1553–1554 Oxytocin, 178, 184 Osteochondrosis of elbow, 277 Osteoid osteoma, 1554 Osteomas, 1554 P Osteonecrosis, 1477–1478 p53, 1203 Osteopathic manipulation, 1776–1777 Pacemakers and defibrillators, 990–991 Osteopenia, 1387, 1687 Paget’s disease, 1557–1558 Osteoporosis, 89, 1387, 1461–1462 Pain, 1163 bone densitometry assessment, 1686–1687 Pain-based CBT, 1550 diagnosis of, 1688 acute, 788 fracture, 1685 chronic, 787 FRAX score, 1687 inflammatory, 788 prevention and treatment, 1688–1691 mechanical, 789 primary, 1685 muscular, 788 risk factors for, 1686 neuropathic, 789 secondary, 1685–1686 patient assessment, 788 Osteosarcoma, 1555–1557 treatment, 788–789 Otitis externa types of, 788–789 complications, 934 Pain disorder, 450 definition, 931–932 Pain management, 328, 1161 diagnosis, 932, 934 Pain syndrome, 1545 epidemiology, 932 Palivizumab, 245, 515 monitoring, 933–934 Palliative care, 1108 pathophysiology, 932 Palliative Performance Scale (PPS), 799 prevention, 934 Palliative sedation, 803 treatment, 932–933 Pallidotomy, 856 Otitis media with effusion (OME), 246 Palmar xanthomas, 1640 Otoacoustic Emission (OAE) test, 950 Palpable mass, 1429, 1555 Otolaryngologist, 958 Palpitations, 1061, 1065 Otolaryngology, 950, 955 Pancoast syndrome, 1107 Otologic injury, 1325 Pancreatic calcifications, 1161 Ototoxic agents, 949 Pancreatic cancer, 1161, 1163–1164 Ototoxic medications, 951 Pancreatic duct stones, 1161 Outlet forceps, 188 Pancreatic enzyme, 1161 Outpatient Comprehensive Geriatric Assessment Pancreatic insufficiency, 1160–1161 (CGA), 311 Pancreatic necrosis, 1160 Outpatient management, 1046 Pancreaticoduodenectomy, 1164 Ova and parasite, 569 Pancreatitis, 1161, 1710 Ovarian cancer Pandemics, 515 definition, 1406 Pandora’s box, 1212 diagnosis, 1407 Panic attacks, 413–414 environmental risk factors, 1407 Panic disorder, 414 epidemiology, 1406 Pap smear, 1402, 1406 family history, 1406–1407 Papular acrodermatitis of childhood (PAC), 248–249 obesity, 1407 Papulosquamous, 1626 prevention, 1408 Paradoxical pulse, 1054 ® reproductive/hormonal factors, 1407 Paragard , 1339 1848 Index

Parainfluenza virus, 514 PDE5 inhibitors, 1298 Paralabral cyst, 1498 Peak expiratory flow (PEF) rate, 1075 Paralysis, 1241 Pediatric(s), 106, 676 Paranasal sinuses, 242 Pediatric Autoimmune Neuropsychiatric Disorders Paraneoplastic syndrome, 1107 Associated with group A streptococcal infections Paranoid personality disorder, 464 (PANDAS), 292 Parasomnias, 726, 731 Pediatric carbon monoxide poisoning, 601 Parathormone (PTH), 1708 Pediatric hearing loss, 949–950 Parathyroid hormone (PTH), 1690 congenital/acquired, 949 Parathyroids, 1708–1710 evaluation and diagnosis, 949–950 Parenchymatous syphilis, 880 treatment, 950 Parent training, 261 Pediatric malignancies, 1555 Parenting styles, 261 Pediatric OSA, 730 Paretic neurosyphilis, 880 Pediculosis, 1360, 1596 Parietal abdominal pain, 1212 Pediculosis capitis, 1596 Parkinsonian, 856 Pediculosis corporis, 1596 Parkinsonism, 851–856 Pedigree of Genogram, 207 Parkinson’s disease with dementia, 341 Pelargonium sidoides, 510 Parkinson’s tremor, 856 Pelvic floor dysfunction, 198 Paromomycin, 570 Pelvic inflammatory disease (PID), 529, 532–534, Paronychia, 1487, 1629 1437–1438 Parotid gland, 952 Pelvic pain Paroxetine, 853, 1390 in men, 1440 Parsonage-Turner syndrome, 866 in women (see Acute pelvic pain) Partial hospital programs, 764 Pelvic peritonitis, 532 Partial seizures, 826 Penetrating injuries, 1217 Partial thickness burns, 656, 658 Penicillin, 493, 880 Partner violence, 236–237 Penicillin-allergic patients, 524 Parvovirus B19, 1063, 1729 Penicillin allergy, 534 Passive suicidal ideations, 441 Penicillin/cephalosporin allergy, 530–531 Patch testing, 1575 Pencillin G, 536 Patella dislocation, 689–690 Pentoxifylline, 1053, 1175 Patella dislocations, 1505 Peptic ulcer disease (PUD) Pathologic fractures, 1557 complication of, 1135 Pathophysiology, 1148 diagnosis, 1135 Patient assessment, 788 treatment, 1135–1136 Patient Care Management (PCM), 63 Peptic ulcers, 841 Patient Centered Medical Home (PCMH), 61–63, 95–96 Perceptual isolation, 725 Patient centered outcomes, 1785 Percutaneous coronary interventions (PCI), 1031 Patient education, 92, 722, 812 Perennial allergic conjunctivitis, 895 Patient Health Questionnaire for Adolescents (PHQ-A), 83 Perennial allergic rhinitis, 482 Patient Health Questionnaire (PHQ–9) scores, 425 Perforation, 1200 Patient portals, 1765–1766 Performance status, 1107 Patient preparation for surgery Perianal hematoma, 1184 etiology of acute abdominal pain seeking emergency Periarthritis. See Frozen shoulder care, 1216 Periarticular shoulder problems, 1476 laparoscopic surgery, 1216 rotator cuff injuries, 1476 life threatening causes, 1217 subacromial bursitis, 1476–1477 perioperative glucose control, 1216 Pericardial friction rub, 1053 pre-operative testing, 1215 Pericardiectomy, 1055 resuscitation, 1215–1216 Pericardiocentesis, 1054 Patient Protection and Affordable Care Act (PPACA), 61 Pericarditis Patient-oriented evidence, 51 differential diagnosis, 1054 Patient-oriented evidence that matters (POEM), 51 etiologies of, 1053 Patient-oriented outcome, 51 intervention, 1054–1055 Patrick’s test, 1459 presentation and diagnosis, 1053–1054 Pauci-immune complex glomerulonephritis, 1277 Pericolic abscess, 1151 PCMH Model, 1798–1800 Perimenopause, 21, 1382 PCSK9, 1638 Perimesencephalic non-aneurysmal hemorrhage, 846 Index 1849

Perinatal morbidity and mortality, 128–129 other, 262 Perineal pain, 198 prevalence, 262 Period of Purple Crying, 364 situational, 262 Periodic acid-Schiff (PAS), 1628 Phosphodiesterase-5 inhibitors, 1116 Periodontal diseases, 938–939 Photodermatitis, 1580 Periodontitis, 939 Photosensitivity dermatitis, 1625 Peripartum cardiomyopathy (PPCM), Phototherapy, 1570 1066–1067 Phototoxic reactions, 1625 Peripheral artery disease (PAD) Physeal fractures, 271–272 amputation, 1052 Physical abuse, 348 differential diagnosis, 1052 Physical activity, 88, 1689 intervention, 1052–1053 for adults, 101–102 presentation and diagnosis, 1052 for children and adolescents, 101–103 prevalence of, 1052 counseling, children and adolescents, 102 Peripheral DXA (pDXA), 1687 during pregnancy, 100 Peripheral edema, 461 older adults, 101–102 Peripheral vascular disease (PVD), 1658 regular, 100 Peritonsillar abscesses, 245, 523 Physical activity guidelines, 668 Peri-ungual warts, 1592 Physical deficits, 559 Pernicious anemia, 1730 Physical exam, rhinosinusitis, 520–521 Peroneal Neuropathy, 865 Physical examination, 811 Persistent allergic rhinitis, 482 Physical therapy, 1520 Persistent depressive disorder, 425 Physical urticaria, 1577 Persistent mental disorder, 444 Physical violence, IPV, 368 Personal computers, 1759 Physician-assisted suicide, 803 Personality disorders, 442, 444, 463–466, 711 Physician, family cluster A personality disorders, 464 future, 1789–1790 cluster B personality disorders, 464–465 generalist, 1786 cluster C personality disorders, 465–466 history of, 1786–1787 Personalized medicine, 212 role, 1786–1788 Pertussis, 244 Physician Orders for Life-Sustaining Treatment Pes anserine bursitis, 1503–1504 (POLST), 803 Pes cavus, 284 Physicians Quality Reporting System (PQRS), 1760 Petechiae, 502 Physiologic tremor, 856 Petechial, 567 Physiotherapy, 1298, 1552 Pharmacogenomics, 212 Pica, 265–266, 460 Pharmacologic Management, 309 complications, 266 Pharmacologic synergy, 1057 consumption of non-food items, 265 Pharmacotherapy, 704, 722 cultural practices, 266 Pharyngitis, 245, 522–523 SSRI, 266 Phased approach, 1507 PICO, 50 Phemphigoid vulgaris, 1581–1582 Pigmentation, 1624 Phenolization, 1629 Pilocarpine, 954 Phenylephrine eye drops, 896 Pimecrolimus, 1565 Phenylketonuria (PKU), 78 Pingueculum, 918 Phenytoin, 465, 853 Pink eye, 890 Phlegmons, 1151 Pinworm infestation, 251–252 Phobias, 262–263 Pioglitazone, 1661 animals, 262 PIP joint dislocations, 1484–1485 behaviorally, 262 Pituitary deficiency, 1702–1704 blood-injection-injury, 262 Pityriasis, 1624–1625 cognitive restructuring, 262 Pityriasis rosea, 248, 249, 1578–1579 cognitive-behavioral treatments (CBT), Pityrosporum orbiculare, 1596 262–263 Pityrosporum ovale, 1596, 1625 emotion regulation, 262 PIVOT study, 1308 environmental influences, 262 PIVOT trial, 1308 gender differences, 262 Placenta abruption, 180 medications, 263 Placenta accreta, 181 natural environment, 262 Placenta previa, 180 1850 Index

Placenta previa (cont.) Polyhydramnios, 189 diagnosis, 171 Polymerase chain reaction (PCR), 565 epidemiology, 171 Polymerase chain reaction (PCR) assay, 539 etiology, 171 Polymyalgia rheumatica (PMR), 1538–1539 management, 171–172 Polyneuropathy, 862 prevention, 171 Polypharmacy, 326–328 Placental separation, 151 Polyps, 1200 Plain abdominal x-rays, 1227 Polysomnography (PSG), 728 Plain radiography, 1328 Polyuria, 1705–1706 Plant sterols/stanols, 1646 Pompholyx, 1564 Plantar fascia rupture, 1510 Pooling, 182 Plantar fasciitis, 1509–1510 Poor nutrition, 40 Plantar fasciopathy, 1509–1510 Popliteal artery, 1505 Plantar flexors, 1505 Popliteal cyst, 1502–1503 Plantar warts, 1592 Popliteal fossa, 1502 Plantaris injuries, 1507 Popliteus muscles, 1505 Plantaris muscle, 1505 Pop-offs, 188 Plaque psoriasis, 1569 Population health Plasmacytoma, 1462 definition, 60–61 Plasmapheresis, 868 medical home, 61–63 Plastic deformation fractures, 272 in neighborhood, 63–65 Platelet rich plasma (PRP), 1497 primary care, 61 Pleural effusions, 1118–1120 total population health, 65–66 Pleural fluid analysis, 1119 Population management, 1785 Pleuritic chest pain, 1117–1118 Portal hypertension, 1175 Pneumatic compression, 846 Portion size, 706 Pneumatic otoscopy, 244 Positive expiratory pressure (PEP), 1124 Pneumococcal, vaccination, 1081 Positron emission tomography (PET), 1107–1108 Pneumococcus bacteria, 84 Post exposure prophylaxis (PEP), 383 Pneumocystis pneumonia (PCP) Post-traumatic stress disorder (PTSD), 383 definition/background, epidemiology, 1099 Posterior dislocations, 1476 history and physical exam, 1099 Posterior fat pad sign, 1478 laboratory and imaging, special testing, 1100 Posterior interosseous nerve syndrome, 864 prevention and community issues, 1100 Posterior scleritis, 897 treatment, 1100 Posterior segment injuries, 910 Pneumomediastinum, 654–655 Posterior tibial nerve, 1509 Pneumonia, 159, 512, 1080 Postexposure prophylaxis (PEP), 546 bacterial pneumonia, 1084–1089 Post-graduate training, 713 M. pneumonia, 1089–1090 Postherpetic neuralgia, 867, 1592 PCP, 1099–1100 Postmenopausal period, 1383, 1385 viral pneumonia, 1090–1092 Postmenopausal women, 1386–1387 Pneumonitis, 502 Postnasal drip syndrome. See Upper airway cough Pneumoperitoneum, 1116 syndrome (UACS) Pneumothorax, 654–655 Postpartum blues, 198 PSP, 1117 Postpartum contraception, 198 SSP, 1117–1118 Postpartum depression, 197 tension pneumothorax, 1118 incidence, 200 Podagra, 1713 psychosocial and psychological interventions, 200 Podocytes, 1280 risk factors, 200 Podofilox, 538 screening, 200 Podophyllin, 538 symptoms, 200 Point of care, 1763 Postpartum endometritis Poison ivy, 1574 incidence, 196 Policosanol, 1646 risk factors, 196 Polio vaccination, 115 symptoms, 196 Polycystic kidney disease (PCKD), 839 treatment, 196 Polycystic ovary syndrome, 1377–1379 Postpartum gestational hypertension, pre-eclampsia, and Polycythemia, 1749 eclampsia, 196 Polydipsia, 1705 Postpartum hemorrhage Index 1851

cause, 195 physical examination, 132 coagulopathy, 196 previous obstetrical history, 131 definition, 195 Reproductive Life Plan, 136 drastic measures, 196 risk factors, 129, 133 prevention, 195 sexually transmitted infections, 133 retained placental tissue, 196 social history, 131–132 risk factors, 195 standard nutritional recommendations, trauma, 195 132–133 uterine atony, 195 vaccine preventable infections, 133 Postpartum immunization, 197 Preconception counseling, 20 Postpartum infection, 196–197 Preeclampsia, 162 Postpartum thyroid dysfunction, 200 Pre-exposure prophylaxis (PrEP), 546 clinical course, 200 Pregabalin, 1548 Postpartum venous thromboembolism Pregnancy, 87, 156, 529, 531–532, 536–537, 539–540, diagnosis, 200 675, 756, 1081, 1724 risk, 200 Pregnancy test, 382 treatment, 200 Pregnant women, IPV, 371 Postpartum wound infection Pre-hypertension, 965 causative organisms, 197 Premalignant, 1603 risk factors, 197 Premature atrial contractions (PACs), 995–996 Postseptal cellulitis, 919 Premature ejaculation, 751–752 Post-streptococcal glomerulonephritis, 1276 Premature rupture of membranes, 181–182 Poststreptococcal reactive arthritis, 524 Premature ventricular contractions (PVCs), 997 Postterm gestation, 185 Prematurity, 290 Postterm pregnancy, 182–183 Prenatal care, 141 Posttraumatic stress disorder (PTSD), 412, 415–416, 731 after conception, 142 Posture-induced radial neuropathy, 864 and alcohol, 143 Post-vasectomy pain syndrome, 1317 first prenatal visit, 143 Potassium citrate, 1331 Infection precautions, 144 Potassium disorders pregnancy planning, 142 hyperkalemia, 1263–1264 and smoking, 143 hypokalemia, 1261–1263 traditional, 142 Potassium sparing diuretics, 968 work, 144 Pramipexole, 854 Prenatal screening, 144–145 Pramipexole (Mirapex), 854 Prenatal vitamins, 143 Pramlintide, 1665 Preparticipation screening, 1062 Praziquantel, 1143 Pre-patellar bursitis, 1504 Preadolescent acne, 1571 Presbyopia, 925 Preauricular lymphadenopathy, 890 Prescription medication abuse, 443 Pre-cancerous polyps, 1208 Preseptal cellulitis, 919 Precocious puberty, 1706 Pressure sores, 841 Preconception care Pressure ulcers, 332 adverse birth outcomes, 133 Preterm labor and delivery barriers, 129, 131 diagnosis, 172–173 CDC recommendations, 129 epidemiology, 172 chronic medical conditions, 133–134 etiology, 172 definition, 128 management, 174 environmental history, 132 prevention, 173–174 family, 137 Preterm premature rupture of membranes, 181–182 family history, 131 Pretest probability, 974 issues for men, 137–138 Pretrip consultation key partnerships and resources, 138 altitude illness prophylaxis, 119–120 laboratory evaluation, 133 diarrhea prophylaxis, 117–118 medication history, 132 malaria prophylaxis, 118–119 novel approaches, 136–137 medical history, 114 nutritional status, 132 personal protective measures, 119 opportunities, 131 routine vaccinations, 114 past medical history, 131 safety and accident prevention, 120 perinatal morbidity and mortality, 128–129 travel related vaccinations, 114–116 1852 Index

Prevalence, 699 Prostate cancer, 88, 1297, 1306 Preventable diseases, 100 Prostate-specific antigen (PSA), 1303, 1710 Prevention, 706, 1628 Prostatitis, 1299 Primaquine, 118–119 Prosthetic valve(s), 1057 Primary amenorrhea, 1371 Prosthetic valve endocarditis (PVE), 1055 Primary brain tumors Protective factors, 442 incidence of, 881 Proteinuria, 1278, 1280, 1288 types of, 881 Proton pump inhibitors (PPIs), 1134, 1136 Primary care concept, 1786 Protozoa, 569 Primary cesarean delivery, 183 Protozoal parasite, 562 Primary constipation, 308 Provider-patient relationship, 1785 Primary dysmenorrhea, 1379 Proximal fifth metatarsal fracture, 694 Primary frailty, 306 Proximal humeral fractures, 1478 Primary lung cancers, 881 Pruritis, 1163 Primary open-angle glaucoma (POAG), 923 Pruritus ani Primary osteoporosis, 1685 background, 1191 Primary prevention, 839 causes, 1191 Primary prevention, lung cancer diagnosis, 1191–1192 cigarette smoking, 1104 treatment, 1192 genetics, 1105 Pseudocyesis, 455 nutrition and exercise, 1105 Pseudocyst, 1160–1162 occupational and environmental exposure, 1104–1105 Pseudodementia, 340 Primary spontaneous pneumothorax (PSP), 1117 Pseudohyphae, 1353 Primary syphilis, 534 Pseudopapilledema, 923 Primidone, 857 Psoriasis, 1568–1570 Prion disease, 341 Psoriatic arthritis, 1541 Prior surgery, 1213 Psychiatric disorder, 450 Probenecid, 533, 880 Psychiatric referral, 1631 Probiotics, 1239 Psychiatry, 444 Problem-solving approaches, 456 Psychodynamic psychotherapy, 456 Procalcitonin-guided therapy, 514 Psychoeducation, 408 Procedural sedation and analgesia (PSA), 636–638 Psychogenesis, 452 Processed meat, 1202 Psychogenic tremor, 856, 858 Proctosigmoidoscopy, 1192 Psychological abuse, 348 Prodrome, 540 Psychological aggression, IPV, 369 Progesterone receptor, 1431 Psychological therapies, 436 Progestin-only contraceptive, 198 Psychosocial and behavioral interventions, The Program of All-Inclusive Care for the Elderly 764–765 (PACE), 311 Psychosocial stressors, 1546 Prognosis, 1106 Psychosomatic disorders, 449–450 Prognosis at End-of-Life, 798–800 Psychotherapy, 446, 789, 858 Progressive muscle relaxation, 1775–1776 Pterygium, 918 Progressive supranuclear palsy (PSP), 342, 854 Puberty, 19–20, 1706 Prolactin, 1702 Pubic lice, 1596 Prolapsed and strangulated hemorrhoids, 1184 Public health, role in, 1178 ® Proliferative lesions without atypia, 1421 PubMed , 50, 1765 Proliferative retinopathy, 1656 ω3PUFA, 1645, 1646 Prolotherapy, 1497 Puffer fish, 1240 Prophylactic treatment Pull test, 852 chronic TTH, 818 Pulmonary angiography, 1045 cluster headache, 817–818 Pulmonary arterial hypertension (PAH), migraine, 815 1068–1069 Prophylaxis, 75, 84 Pulmonary barotrauma, 655 Propofol, 763 Pulmonary embolism (PE), 157, 841, 1068 Propranolol, 857 acute massive PE, 1046 Proprotein convertase subtilisin/kexin type 9, 1638 Geneva criteria, 1043 Propylthiouracil, 1674 pretest probability for, 1044 Prostanoids, 1116 sub-massive PE, 1046 Prostate, 1294 Well’s criteria, 1043 Index 1853

Pulmonary hypertension (PH), 1067 Radionuclide perfusion imaging, 976 classification and epidemiology of, 1067, 1114 Radon exposure, 1104 congenital heart disease, 1115 Raloxifene, 84 differential diagnosis, 1068 RANK ligand inhibitor, 1690–1691 dyspnea on exertion, 1114 Ranolazine, 979 intervention, 1068–1069 Rapid acting analog (RAA) insulin, 1655, 1658–1659 management, 1115–1116 Rapid antigen detection test (RADT), 243, 523 presentation and diagnosis, 1068 Rapid influenza diagnostic tests (RIDTs), 512–513 pulmonary arterial hypertension, 1114 Rapidly progressive glomerulonephritis, 1277–1278, 1284 pulmonary arterial pressure, 1114 Rash, 566, 571 pulmonary venous hypertension, 1114 Rates, 257 right bundle branch block, 1115 Raw/under cooked meat, 568 right heart catheterization, 1115 Raynaud’s disease (Primary Raynaud’s phenomenon), right ventricular hypertrophy, 1115 1535–1536 six minute walk test, 1115 Reactive arthritis (Reiter syndrome), 1532–1533 Pulmonary rehabilitation, 1068, 1081 Reactive attachment disorder, 413 Pulse dosing, 1594 Reattribution, 456 Punch biopsy, 1620 Rebound tenderness, 1212 Pupil Receiver operating characteristic (ROC) curves, 73 constriction, 916 Receptor tyrosine kinase, 1108 dilatation, 916 Reciprocal licensing, 1766 Pure tone audiometry, 949 Recombinant activated factor VII (rVIIa), 845 Purging, 462 Recombinant immunoblot assay (RIBA), 1173 Purpuric, 567 Recombinant tissue plasminogen activator (rTPA), 843 Purulent discharge, 890 Rectal bleeding, 1200 Pustular psoriasis, 1569 Rectal prolapse Pyelonephritis, 154 background, 1190 Pyogenic granuloma, 944, 1615 diagnosis, 1190–1191 Pyrantel pamoate, 252, 1143 non-operative approach, 1191 Pyrimethamine, 565 treatment, 1191 Pythirus pubis, 1596 Rectum, 1182 Pyuria, 1250, 1281 Rectus femoris, 1499 Recurrence, 1431, 1432 Recurrent croup, 246 Q Recurrent cystitis, 1248 Quad screen, 146 Recurrent infection, 524 Quadriceps and hamstring injuries, 1499–1500 Recurrent pericarditis, 1054 Quadriceps and patellar tendon tears, 1504 Recurrent urolithiasis, 1330 Quadriceps tendinopathies, 1500 Red and white zones, 1500 Quadruple marker test, 146 Red blood cells (RBCs), 1719 Quality of care, 1787 Red bug, 1598 Quality of life, 704 Red cell distribution width (RDW), 1721 Quantitative computed tomography (CT) scan, 1687 Red cell dysplasia, 1729 Quantitative ultrasonography (QUS), 1687 Red eye, 904 Quetiapine, 853 acute closed angle glaucoma, 899–900 Quickening, 145 conjunctivitis (see Conjunctivitis) definition, 889–890 episcleritis, 896 R herpes keratitis, 898–899 Rabies, 116–117 iritis, 897–898 Race, 28–30, 33 scleritis, 896–897 Racial disparity, 699 trichiasis, 899 Radial head subluxation, 277–278 Red flag symptoms, 1457 Radial nerve palsy, 862 Red flags, 289–290 Radial scar, 1421 Red rice yeast, 1646 Radial tunnel syndrome, 864 Redesign, 1786 Radiation, 599–600 Reduced motivation/energy, 726 Radioallergosorbent test (RAST), 895 Re-entry, 985 Radiolucent lytic lesion, 1554 Refeeding, 461 1854 Index

Refeeding syndrome, 461 Retinal disorders, 919–922 Reference value, 77 Retinal hemorrhages (RH), 361 Referral to cardiologist, 991 Retinal scarring, 563 Referred pain, 1212 Retinopathy, 1656 Refractive disorder, 925 Retirement, 22–23 Refractory ulcers, 1136 Retrograde pull, 661 Registry, 1760 Retropharyngeal abscesses, 523 Reimbursement models, 1788 Return-to-play, 505 Reiter syndrome, 897 Reverse transcriptase polymerase chain reaction Relapse prevention, 765 (RT-PCR), 571 Relationship-based health care, 7 Reversible dementia, 340 Relative risk reduction, 52 Rhabdomyolysis, 1643 Relative survival rate, 1432 Rheumatic disorder, 1546 Relaxation, 721 Rheumatic heart disease, 1055 Relaxation response, 106 Rheumatoid Arthritis (RA), 897 Relaxation/support, 721 2010 ACR-EULAR classification criteria, 1528 Religion, 30, 33 background and pathophysiology, 1527 REMS behavior disorder (RBD), 731 clinical course and disease activity, 1530–1531 Renal cell carcinoma, 1289–1290 clinical presentation, 1527–1528 Renal colic, 1327 diagnosis, 1528 Renal replacement therapy, 1289 juvenile idiopathic arthritis (JIA), 1531–1532 Renal vein thrombosis, 1280 laboratory and imaging Studies, 1528–1529 Renin, 1712 nonpharmacologic treatment, 1529 Renin-angiotensin inhibitors, 978 vs. osteoarthritis, 1531 Repeated testing, 289 pharmacologic therapy, 1529 Repetitive behaviors, 475 surgery, 1530 Reproductive Life Plan, 136 treatment, 1529 Request for proposals (RFP), 1760 Rhinophymatous, 1573 Resection, 1164 Rhinorrhea, 510 Reserpine, 853 Rhinosinusitis, 519–522 Residential care programs, 764 Rhinovirus, 242 Resistance exercise, 101 Rhinoviruses, 510 Resistant hypertension, 970–971 Rhogam, 197 Resisted straight leg raise, 1495 Rickettsial infection, 566 Respiratory alkalosis, 1266 Right heart catheterization (RHC), 1067 Respiratory disorders Right ventricular failure (RVF), 1068–1069 ARDS, 1112–1114 Rightward torqueing, 1206 atelectasis, 1121–1122 Rigid flatfoot, 284 bronchiectasis, 1122–1124 Rigidity, 852, 1212 ILD, 1120–1121 Ringworm, 1593 pleural effusions, 1118–1120 Risk, 700 pneumothorax, 1116–1118 Risk category, 444 pulmonary hypertension, 1114–1116 Risk evaluation mitigation strategies (REMS) pulmonary sarcoidosis, 1124–1126 program, 1661 Respiratory distress, 218 Risk factors, rhinosinusitis, 520 Respiratory droplets, 508 Risk models, 1427 Respiratory failure, 1241 Risk Stratification of Syncope in the Emergency Respiratory papillomatosis, 539 Department (ROSE), 1035 Respiratory syncytial virus, 510, 1112 Risperidone, 853 Respiratory syncytial virus infections (RSV), 246 Rivaroxaban, 1046 Restless leg syndrome, 731, 1720 RNA-associated silencing, 214 Restricted movement, 1517 Rocky Mountain spotted fever (RMSF), Restricting access, 445 566–568 Restriction, 705 Rodents, 575 Restrictive cardiomyopathy (RCM), 1063 Rolandic epilepsy, 829 Resuscitation of newborn, 218 Ropinirole (Requip), 854 Reteplase, 843 Rosacea, 1572–1573 Reticulocyte index, 1723 Roseola infantum, 247 Retinal detachment, 910–911, 920 Rosiglitazone, 1661 Index 1855

Rosiglitazone Evaluated for Cardiovascular Outcomes and Scleritis, 896–897 Regulation of Glycaemia in Diabetes (RECORD) Sclerosing adenosis, 1421 trial, 1661 Sclerotherapy, 1183 Rotator cuff injuries, 683–684 Sclerotic/morpheaform, 1608 Rotavirus, 250, 1235 Scoliosis, 1554 Rotigotine (Neupro), 854, 855 Scombroid fish poisoning, 1238 Roux-en-Y gastric bypass (RYGB), 704 Screen time, 706 RPR, 535 Screening, 774, 1326, 1602 Rubber band ligation (RBL) technique, 1183, 1191 CRC, 1203 Rubella, 247, 563 pancreatic cancer, 1163–1164 Rubeola, 247 Screening, Brief Intervention, and Referral to Treatment Rule of 9’s, 657 (SBIRT) model, 774 Rule of 10, 658 Screening test Rule-based systems, 1765 accuracy, 73 Rumination disorder, 460 cutoff criterion, 72–73 Ruptured popliteal cyst, 1503 lead time bias, 72 Ruptured sebaceous cyst, 1617 length bias, 72 Rupturing membranes, 189 negative likelihood ratio, 73 RxNORM, 1765 positive likelihood ratio, 73 predictive value, 73 in pregnancy, 144 S prevalence, 73 S3, 1063, 1068 specificity, 72–73 S4, 1061, 1068 Scrotal mass, 1321 Sacroiliac joints, 1459 Scybala, 1597 Safe sleep, 75 Seasonal allergic conjunctivitis, 895 Safe sleep practices, 18 Seasonal allergic rhinitis, 482 Sail sign, 1478 Seated slump test, 1458 Salaam attacks, 828 Sebaceous cyst, 1617–1618 Saliva, 953 Seborrheic dermatitis, 1567–1568 Salivary glands, 952–953 Seborrheic keratosis, 1602–1603 Salmeterol, 1080 Second stage labor, 188 Salmonella, 1142, 1234, 1235 Second trimester, 145 Salmonella enterica, 1145 Secondary amenorrhea, 1371–1373 Salter-Harris classification, 271 Secondary constipation, 308 San Francisco Syncope Rule (SFSR), 1035 Secondary dyslipidemias, 1640 Sandwich generation, 21 Secondary dysmenorrhea, 1379 Sarcoidosis, 1124–1126, 1283, 1704 Secondary frailty, 306 Sarcoptes scabiei, 1597 Secondary hemorrhage, 846 SARS-CoV, 515 Secondary osteoporosis, 1685 Sartorius muscle, 1503 Secondary prevention, 839 Satellite colonies, 1595 Secondary prevention, lung cancer, 1105–1106 Satiety, 702 Secondary spontaneous pneumothorax (SSP), 1117–1118 Saw palmetto, African plum, 1298 Secondary syphilis, 534 Scabies, 1597 Secondhand smoke, 75 Scaphoid fracture, 686–687 Sedatives, 722 Scapula, 1475 Sedentary behavior, 103 Scapular fractures, 1475 Seizure disorders in pregnancy, 160 Scarlatiniform rash, 243–244 Seizures, 504, 824–825 Scarlet fever, 249 in adolescence, 829 Scheuermann disease, 276–277 AEDs, 833 Schilling test, 1730 in childhood, 828–829 Schistosoma haematobium, 1326 electroencephalography (EEG), 830–833 Schistosomiasis, 119 FDG-PET scan, 833 Schizoid personality disorder, 464 first seizure, 836 Schizotypal personality disorder, 464 focal seizures, 824, 825 School bullying, 413 generalized seizures, 824–825 Sciatic neuropathy, 865 history of, 829–830 Scleral edema, 897 MRI, 830 1856 Index

Seizures (cont.) Sexual characteristics, 1706–1708 in neonates and infants, 827–828 Sexual dysfunction neurological exam, 830 definition of, 743–744 status epilepticus, 833–835 diagnosis, 746 SUDEP, 835–836 general principles, 747–749 surgery, 833 history, 745 syndromes by age group, 827 in men, 750–752 vagal nerve stimulation, 833 physical exam, 745–746 video-EEG monitoring, 833 referrals, 752–753 Selective mutism, 412, 413 in women, 749–750 Selective serotonin reuptake inhibitors (SSRIs), 200, 343, Sexual history, 541 417, 431, 445, 463, 465, 1390 Sexual identity and development, 20 Selegeline, 855 Sexual partner, 532, 534, 537 Selegiline (Eldepryl), 854, 855 Sexual violence, 368–369 Self-control, 701 Sexuality after childbirth, 198 Self-harm, 443 Sexuality in pregnancy, 198 Self-mutilation, 465 Sexually transmitted infections (STIs), 78, 83, 87, 133, Semimembranosus, 1499 528, 531 Seminoma, 1324, 1325 Shaken baby syndrome, 911 Semitendinosus, 1499 Shared decision making Semitendinosus muscle, 1503 barriers to, 56 Sensorineural hearing loss, 948 models for, 56 Sensory deficits, 23 process description, 55 Separation anxiety disorder, 412, 413 Shave excision, 1619–1620 Sepsis, 185, 196, 555 Sheehan syndrome, 1704 Sepsis-induced hypotension, 556 Shellfish poisoning, 1240 Septic hip, 282 Shigella, 1142, 1234 Serological tests, 880 Shingles, 1591 Seronegative spondyloarthropathies, 1509 Short QT, 1710 Serotonin norepinephrine reuptake inhibitors (SNRIs), Shoulder, 1475 417, 1390 dystocia, 186–187 Serotonin receptor agonists, 855 instability, 684–685 Serous cystadenomas (SCA), 1162 traumatic dislocation, 1475–1477 serovar Typhi, 1145 Show Your Love” Campaign, 137 Serrated pathway, 1203 Sialadenitis, 952–953 Sertraline, 853 Sick building syndrome (SBS), 590–592 Serum cortisol, 1711 Sick sinus syndrome (SSS), 997 Serum creatinine, 1283 Sickle cell disease, 78, 1750–1751 Service industries, 1789 Side effects of HT, 1389 Sesamoiditis, 1511–1512 Sideroblastic anemias, 1726–1727 Seton, 1188 Sigmoid colon, 1206 17p chromosome, 1203 Sigmoidoscopy, 1151 Severe acute bleeding, 1375 Signs of active dying, 802 Severe myoclonic epilepsy of infancy (SEMI), 828–829 Sildenafil, 1298 Sever’s disease, 274 Silent gallstones, 1221 Sexual abuse, 348 Silver nitrate stick, 1365 Sexual assault Silver sulfadiazine, 658 definition, 379 SIMARD MD, 335 emotional reactions and psychological sequelae, 383 Simepravir, 1173 family physicians’ role, 381 Simple interrupted closure, 640 female victims, 380 Simple running closure, 640–641 follow-up, 383 Sinding-Larsen-Johansson syndrome, 273–274 intimate partner violence, 380–381 Sinecatechin, 538 male victims, 380 Sinemet, 854 occurrence, 379–380 Single nucleotide polymorphisms, 207 prevention, 383–384 Single-photon emission CT (SPECT), 1046 sexually transmitted infection prevention, 382–383 Single-question method, 756 short term and long term health effects, 380 Sinus node dysfunction (SND). See Sick sinus victim care, 381–382 syndrome (SSS) Index 1857

Sinus tachycardia, 995 Social phobia. See Social anxiety disorder Sinusitis, 519 Social Security, 22 Sitosterolemia, 1639–1640 Social skills, 19 Sjögren’s syndrome, 1537–1538 Social support, infant risk factors, 236 Skeletal malignancy, 1554 Society of Teachers of Family Medicine, 40 Skin abscess, 1589 Socioeconomic disparity, 699 Skin aging, 1386 Socioeconomic factors, 1103 Skin cancer, 77 Sodium, 105 Skin lesions, 121 Sodium chloride, 1284 Skin testing, 483 Sodium disorders Skin to skin contact, 230 hypernatremia, 1260–1261 Skin to skin contact (SSC), 194 hyponatremia, 1256–1260 ® Skyla , 1339 plasma osmolality (POSM), 1256 Sleep, 725 tonicity, 1256 Sleep apnea, 844 Sodium-glucose cotransporter–2 (SGLT–2) inhibitors, Sleep disturbances, 266, 767, 1384–1385 1663–1664 amnesia, 267 Sodium intake, 967 behavioral factors, 268 Sofosbuvir, 1173 cognitive-behavioral treatments (CBT), 268 Solar lentigo, 1606 cognitive factors, 268 Solar urticaria, 1577 early morning awakenings, 266 Soleus muscle injuries, 1507 emotional regulation, 268 Soluble dietary fiber, 1646 extreme fear, 266 Soluble serum transferrin receptor, 1725 frequent awakenings, 266 Somatic symptom disorder (SSD). See Somatoform insomnia, 266 disorders leaving the bed, 266 Somatoform disorders maintaining sleep, 266 acute somatization, 453 nightmare disorder, 267–268 antidepressant medication, 456 night terrors, 266–267 biomedical model, 450 sleep onset, 266 biopsychosocial approach, 457 sleep-wake cycles, 268 brain-body pathways, 452 sleepwalking, 267 care-seeking behavior, 450 Sleep-related breathing disorders, 726 chronic somatization, 453 Sleep related disorders in elderly, 309–311 comprehensive management, 457 Sleep-related movement disorders, 726 cytokines, 452 Sleep terrors, 267 depression, 450 Sleepwalking, 267, 731 distress, 450 diagnostic feature, 267 early life experiences, 451 prevalence, 267 emotional disturbance, 451–452 rates, 267 FSS, 453 Sleeve gastrectomy (SG), 704 functional impairment, 453 Slipped capital femoral epiphysis, 282–283 inflammatory response, 452 Slit-lamp biomicroscope, 896 legitimacy, 451 Slit-lamp biomicroscopy, 897, 900 lifetime anxiety, 451 Small cell lung cancer, 1106 medical complicity, 452 Small for gestational age, 219 mental disorder, 450 Smoking, 40, 162, 1202–1203 polysymptomatic form, 449–450 cessation, 1081 psychological treatment, 456 pregnancy, 87 stress-diathesis model, 451 primary care for, 87 treatment-seeking behavior, 451 Snakebite, 609 Sore throat, 243 clinical presentation, 610 Sotalol, 857 diagnosis, 610 Sound maskers, 952 management, 610 Sound therapy, 952 prevention, 610 Soy isoflavones, 1391 Snoring, 727 Soy protein, 1646 Social anxiety disorder, 414 Specialist-led follow-up, 1432 Social issues, 1367–1368 Specific phobias, 414 Social neglect, 413–414 Speech and language delay, 80 1858 Index

Speech and language development, 950 Staphylococcus aureus, 890, 1055, 1586 Speech and language pathology, 950, 955 Stapled hemorrhoidopexy, 1184 Speech development and speech dela, 291 Staples, 645 Sperm granulomas, 1317 Starvation, 460 Spermatocele, 1322 Statin therapy, 978 Spermicides, 1346–1347 Statins, 1643 Spherocytes, 1727 Stature, 702–703 Spider bites, 608 Status epilepticus, 833–835 clinical presentation, 608 Status migrainosus, 815 diagnosis, 608 Stauffer syndrome, 1289 management, 608 Steatorrhea, 1160 prevention, 608 Steatosis, 1174 SPIKES Protocol, 798 Steroids, 879 Spina bifida, 75 Stevens-Johnson syndrome, 1580 Spinal malignancy, 1462 Stinger syndrome, 866 Spinal stenosis, 1461 Stomatitis, 940 Spiramycin, 566 Stone analysis, 1330 Spirituality, 33–34 Stone risk profile, 1330 Spirochete, 572 Stones, 953 Spirometry, 1075, 1659 Storage diseases, 1061 Spitz nevus, 1605 Strabismus, 924 SPLATT, 323 Straight-leg raise, 1458 Splenic injury, 505 Stratified primary care management, 1463–1464 Splenomegaly, 505 Streams of development, 288 Spondylolisthesis, 275–276 Strength of recommendation taxonomy, 54 Spondylolysis, 275–276 Strep throat, 502 Spondylosis, 1460 Streptococcal pharyngitis, 503 Spontaneous abortion Streptococcus, 673–674 definition, 166 Streptococcus pneumoniae, 245, 511 diagnosis, 166 Streptokinase, 843 epidemiology, 166 Stress, 387 etiology, 166 cardiomyopathy, 1066 management, 167 echocardiography, 976 prevention, 167 effects of, 393 Sporadic pathway, 1203 fractures, 273, 1491–1492 Spores, 1241 fractures of knee, 1505 Sports anemia, 1719–1720 incontinence, 320–321 Spurious macrocytosis, 1731 internal and external family sources of, 388 Squamous cell cancer, 1609–1610 testing, 975–976 Squamous cell carcinoma, 1106 Stridor, 245 Stabilization, for postresuscitation, 218 Stroke, 837, 858, 1055, 1389 Stable ischemic heart disease, 978–979 Stroke chain, 839 Stage of disease, 1106 Strongyloidiasis, 1142, 1143 Stages of change (SOC) model, 109 Structured medication review (SMR), 327–328 Stages of Reproductive Aging Workshop (STRAW), ST-segment elevation myocardial infarction (STEMI), 1382–1383 974, 976–977 Staging of pressure ulcers, 332 Subacromial bursitis, 1476–1477 Stalking, IPV, 369 Subarachnoid hemorrhage (SAH), 838, 846–847 Stammering, 263 Subclinical hyperthyroidism, 1676 communicate effectively, 264 Subclinical hypothyroidism, 1677–1678 frequency and severity, 264 Subconjunctival hemorrhage, 905, 918 improve oral communication, 264 Subcutaneous fissurotomy, 1186 risk factors, 264 Subdermal contraceptive implants, 1340–1341 speak fluently, 264 Subgaleal hemorrhage, 224 standardized assessments, 264 Sublingual gland, 952 Standardized terminology, 1765 Submandibular gland, 952 Standard resection, CRC, 1207 Submersion injury and drowning, 651–653 Standing orders, 95 Substance abuse, 444 Staphylococcus, 673–674 Substance dependence, 443–444 Index 1859

Substance/medication-induced OCD, 415 Survivorship, 559 Substance/medication-induced sexual dysfunction, 752 Sustained virologic response (SVR), 1173 Substance use, 87 Swallowed foreign body Substance use disorder, 773–774 definition/background, 659 Subungual hematoma, 1629 history, 659 Subungual infections, 1628 laboratory and imaging, 659 Suction ligation, 1183 physical examination, 659 Sudden cardiac death (SCD), 1024, 1036–1037, 1060, prevention, 660 1062 treatment, 659–660 primary prevention, 1037 Swine, 568 risks for, 1036 Symptomatic relief, 510 secondary prevention, 1037 Symptom-triggered schedule, 762 Sudden infant death syndrome (SIDS), 17, 234, 1066 Syncope, 1061 Sudden Unexpected Death in Epilepsy (SUDEP), 835–836 definition, 1034 Sudeck’s dystrophy, 1551 ECG, 1036 Suicidal ideation, 443 echocardiography, 1036 Suicidality, 465 electrophysiologic testing, 1036 Suicide, 89, 414, 429, 441 history and physical exam, 1035 attempts, 441 management of, 1036 differential diagnosis, 429–430 risk factors for, 1035 risk assessment, 443 routine lab testing, 1036 risk formulation, 443 stress testing, 1036 treatment principles, 430–436 telemetry, 1036 Sulfadiazine, 565 Syndromes, 1106 Sulfonylureas, 1662 Syphilis, 89, 156, 528, 534–537, 563, 879 Sunscreen, 1621, 1627 darkfield examination, 880 Suntanning bed, 1607 intimate contact, 880 Superficial spreading, 1607 Jarisch-Herxheimer reaction, 880 Superficial thrombophlebitis, 1049 meningovascular syphilis, 879 Superior mesenteric artery (SMA) thromboembolic parenchymatous syphilis, 880 occlusion, 1236 penicillin, 880 Superior vena cava syndrome, 1108 physical exam, 880 Supine impingement test, 1495 repeat CSF examination, 880 Supplemental oxygen, 1068 serological evidence of, 879 Support groups, 721 serological tests, 880 Supportive living, 334 treponemal tests, 880 Suppressive therapy, 540 Systematic approach, 1213 Suppurative complications, 523 Systematic approach, headache patient, 809 Supraglottitis, 246 Systematic review, 54–55 Suprasphincteric tract, 1187 Systematized Nomenclature for Medicine-Clinical Supraventricular tachyarryhthmias (SVT), 991–997 Terminology (SNOMED-CT), 1765 Supraventricular tachycardia (SVT), 1035 Systemic chemotherapy, 1431 Surfactant, 1112 Systemic disease, 1160 Surgery, 1058, 1161 Systemic inflammatory response syndrome, 556 cardiac arrhythmias, 991 Systemic lupus erythematosus (SLE), 1626 CRC, 1207 classification, 1534 Surgical excision, 1553 clinical presentation, 1533–1534 Surgical management, rhinosinusitis, 522 history and physical examination, 1533 Surgical myectomy, 1061 laboratory findings, 1534–1535 Surgical patient care, preoperative evaluation pathophysiology, 1533 functional status, 736 treatment, 1535 obstructive sleep apnea (OSA), 736–737 Systemic sclerosis, 1536–1537 perioperative adverse events, risk factors, 736 Systems approach, 95 physical examination, 737 Systolic murmur, 1061 preoperative medical history, 735–737 preoperative risk assessment, 738–741 preoperative testing, 737–738 T Surgical wedge resection, 1107 Tabes dorsalis, 342 Surveillance, 1108 Tabetic neurosyphilis, 880 1860 Index

Tabletop test, 1553 extravaginal torsion, 1311 Tachycardia induced cardiomyopathy, 1067 initial evaluation, 1313 Tachypnea, 220 intravaginal torsion, 1312 Tacrolimus, 1565 neonatal circumcision, 1314–1316 Tadalafil, 1298 occurence, 1311 Tai Chi, 107, 1550 Tetanus prophylaxis, 647 Tailored sphincterotomy, 1186 Tetrabenazine, 853 Takotsubo. See Stress cardiomyopathy Tetracycline, 567 Talipes calcaneovalgus, 283 Tetrodotoxin, 1240 Talipes equinovarus, 284 TFCC injuries, 1482 Talon Noir, 674 Thalamotomy, 856, 857 Tamoxifen, 84, 1390, 1417, 1431, 1432 Thalassemia trait, 1726 Tamsulosin, 1298 Thalassemias, 672, 1726 Tangier disease, 1639 Theophylline, 858 Tanner Stages, 299, 1707 The Triple Test (TTS), 1414–1415 Tardive dyskinesia (TD), 853 Therapeutic lifestyle modifications, 1641, 1643 Tarsal coalition, 284 Thermography, 1551 Tau protein tangles, 341 Thiamine deficiency, 870 Taut palpable band, 1551 Thiazolidinediones, 1661 Tdap vaccination, 84 Thigh compression sleeve, 1499 Teaching practices, 96 Third heart sound, 1004 Tear drop cells, 1723 Third trimester, 146 Tears/strains, 1499 Third trimester screening, 147–148 Teens, IPV, 371–372 Thompson squeeze test, 1506 Telogen, 1629 Thoracentesis, 1118 Telogen effluvium, 1629–1630 Thoracic outlet syndrome, 865–866 Telogen phase, 1629 Thoracotomy, 1118 Temper tantrums, 18, 259 Three point checklist, 1605 cognitive-behavioral treatments (CBT), 261 Throat swab, 243 emotional, 259 Thrombocytopenia, 504, 567, 575 medications, 262 clinical considerations, 1741 physical, 259 etiologies of, 1740 prevalence, 259 ITP, 1739 verbal, 259 treatment of, 1742–1744 Templates, 1765 TTP, 1740 Temporomandibular joint (TMJ) disorders, 942–943 Thrombolysis, 1046 Tender points, 1545 Thrombolytic treatment, 842 Tendon injuries Thrombophilia, 157, 1042, 1048 central slip injuries, 1486 Thrombophilia testing, 1042 mallet finger injuries, 1485–1486 Thrombosis and Myocardial Infarction (TIMI) Tendon xanthomas, 1640 risk score, 976 Tenecteplase, 843 Thrombotic thrombocytopenic purpura (TTP), 1740 10-item version of Difficult Doctor-Patient-Relationship Thrush, 1595 Questionnaire (DDPRQ–10), 716 Thumb-sucking, 264 Tenosynovitis, 1487 cognitive-behavioral treatments (CBT), Tension, 726 264–265 Tension pneumothorax, 655, 1118 dental evaluation, 264 Tension-type headaches (TTH), 818–819 positive reinforcement, 264–265 Teratogenic illnesses, 16 special mouth guards, 264 Terazosin, 1298 Thyroid cancer Terbinafine, 1628 differentiated thyroid cancer cell types, 1682 Terbutaline, 858 undifferentiated thyroid cancer cell type, 1682–1683 Terminal delirium, 802 Thyroid disease Terminal ilium, 1207 Graves’ disease (see Graves’ disease) Tertiary prevention, 839 hyperthyroidism (see Hyperthyroidism) Tertiary syphilis, 534, 536 pregnancy, 1683 Testicular cancer, 1321, 1323–1325 screening for, 1670 Testicular torsion, 1311, 1323 Thyroid hormones, 858 differential diagnosis, 1312–1313 Thyroid nodules Index 1861

evaluation, 1681–1682 TORCH infections, 503 Health Risks and Family Issues, 1680 Torsades de Pointes, 999 Thyroiditis, 200, 1675–1676 Torus, 1480 Thyrotoxic nodule, 1675 Total daily dose (TDD), 1658 Tibial torsion, 279 Total iron binding capacity, 1725 Tick, 566, 572 Total population health, 65–66 Tick bite, 611 Total serum bilirubin (TSB), 221–222 Tics, 263 Toxic epidermal necrolysis, 1580 age of onset, 263 Toxic shock syndrome (TSS), 1440–1441 cognitive-behavioral treatments (CBT), 263 Toxicity, 445 combination, 263 Toxoplasmosis, 502, 562–566 medications, 263 Tracheal deviation, 1118 motor, 263 Trachoma, 894 prevalence, 263 Traction alopecia, 1631 rates, 263 Traditional Chinese medicine (TCM), 1780 vocal, 263 Traffic injuries, 77 Tinea, 1593 Trajectory, 702 Tinea barbae, 1593 Tramadol, 1465 Tinea capitis, 1593, 1631 Tranexamic acid, 847 Tinea corporis, 1593 Trans-abdominal rectopexy, 1191 Tinea corporis gladiatorum (TC), 673 Transaminitis, 502 Tinea cruris, 1593 Trans-anal excision, 1191 Tinea faciei, 1593 Transbronchial lung biopsy, 1125 Tinea gladiatorum, 1593 Transbronchial needle aspiration, 1125 Tinea incognito, 1593 Transdermal patches, 1388 Tinea pedis, 673, 1593 Transesophageal echocardiography (TEE), 1056 Tinea unguium, 1594 Trans fats, 1643 Tinea versicolor, 1595–1596, 1625 Transferrin receptor-ferritin index, 1725 Tinel’s sign, 1552 Transferrin saturation, 1725 Tinidazole, 531, 569 Transglutaminase, 1148 Tinnitus, 951–952 Transient ischemic attacks (TIAs), 838, 841 evaluation, 951 Transient synovitis, 281–282 pathophysiology, 951 Transient tachypnea of newborn, 221 treatment, 952 Transient urinary incontinence, 320 Tiotropium, 1080 Transillumination, 1553 Tissue adhesives, 643–645 Transitions of care, 332–333 Tobacco, 72, 78, 87–88, 1161, 1163 Trans-sphincteric, 1187 Tobacco cessation, 107–109, 1052 Transthoracic echocardiography (TTE), 1056 Tocotrienols, 1646 Trastuzumab, 1431 Toddler stages, 17–18 Trauma, 720 Toe walking, 283 Trauma and Stressor-Related Disorders, 413 Toenails, 1628 Traumatic alopecia, 1631 Tolcapone (Tasmar), 854 Traumatic brain injury, 1704 Tonometry, 900 Traumatic dislocation Tonsillar hypertrophy, 730 anterior dislocation, 1475–1476 Tonsillectomy, 524–525 posterior dislocations, 1476 Tonsillopharyngitis, 522–525 Traumatic retrobulbar hemorrhage, 909 Top of licensure, 1789 Travel immunizations, 23 Tophi, 1713 Treatment, 1362 Topical anesthesia, 635 of GAS Tonsillopharyngitis, 524 Topical antibiotics, 1571 rhinosinusitis, 521–522 Topical decongestants, 486 Treatment and Education of Autistic and Related Topical fluorouracil (5FU), 1604 Communication-handicapped Children (TEACCH) Topical immunotherapy, 1630 Model, 474 Topical NSAIDs, 1519 Treatment plan, 444 Topical retinoids, 1571 Tremor, 852, 856 Topical steroid, 1565, 1582–1583 Trendelenburg sign, 1497 Topical therapy, 932 Treponema pallidum, 534, 535 Topiramate, 463, 767, 857 Treponemal tests, 880 1862 Index

Trial of labor, 183 Two feet–one hand syndrome, 1593 Trial of labor after cesarean, 178 Two glass test, 1304 Trichiasis, 895, 899 2010 revisions to McDonald Criteria, 883 Trichinella spiralis, 568 2013 American College of Cardiology (ACC)/AHA Trichloroacetic acid (TCA), 538 recommendations, 1642 Trichomonads, 1353, 1355 stages of heart failure, 1016 Trichomonas vaginalis, 531 Tympanic membrane dysfunction, 951 Trichomoniasis, 531–532, 1352, 1358–1359 Tympanometry, 949 prevention, 1359 Type 1 diabetes, 159 recurrences/persistence, 1359 Type 2 diabetes mellitus risk factors for trichomoniasis, 1358 α-glucosidase inhibition, 1661–1662 treatment of, 1359 bromocriptine mesylate, 1663 Trichophyton, 1628 colesevelam, 1663 Trichophyton tonsurans, 1593 DPP-IV inhibitors, 1662–1663 Trichotillomania (hair-pulling) disorder, 415, 1631 insulin resistance/sensitivity, 1660–1661 Tricuspid regurgitation, 1068 insulin secretion, 1662 Tricyclic antidepressants, 431, 858 insulin therapy, 1665 Trigeminal neuralgia, 863 prevention of, 1666 Trigger finger, 1486 SGLT–2 1663–1664 Trigger point injections, 1551 weight-based approaches, 1665–1666 Trigger points, 1550 Type 1 RPGN, 1277 Trihexyphenidyl (Artane), 854 Type 2 RPGN, 1277 Trimethoprim-polymyxin B, 892 Type 3 RPGN, 1277–1278 Trimethoprim/sulfamethoxazole, 1303 Type A vitiligo, 1624 Triple Aim, 41 Type B vitiligo, 1624 Triple aim initiative, 1787 Typhoid vaccine, 115 Triple-H therapy, 847 Tzanck preparation, 539 Trochanteric bursitis. See Greater trochanteric pain syndrome (GTPS) Trombicula, 1598 U Tropical pancreatitis, 1160 Ulcerative colitis (UC), 1153, 1203 Trousseau’s sign, 1163 Ulipristal acetate, 1342 Trypanosomiasis, 119 Ultrasound, 953, 1158, 1161, 1328 T-S, 565 Ultraviolet burns, 912 T score, 1687 Ultraviolet light (UVL) exposure, 600 Tubal obstruction and abnormalities, 1450 Umbilical cord prolapse, 188–189 Tubal sterilization, 1347 Uncomplicated pyelonephritis, 1248 Tube thoracostomy, 1117 Underprescribing, 328 Tuberculin skin test (TST), 1093 Underserved populations, 96 Tuberculosis screening, 121–122 Underutilization, 328 Tuberculosis (TB), 155 Unenhanced helical CT, 1328 classification, 1092 Unfractionated heparin (UH), 1046 definition, 1092 Unified Medical Language System (UMLS), 1765 epidemiology, 1092 Unintended pregnancy, 1336 family and community issues, 1094 Unintentional death, 652 history/physical examination, 1093 Unintentional injuries, 77–78 laboratory/imaging, 1093 Unipolar depression, 435 screening, 1092–1093 United Kingdom Prospective Diabetes Study (UKPDS), treatment, 1093–1094 1652 Tuberoeruptive xanthomas, 1640 United Stated Preventative Services Task Force, 756 Tuberous sclerosis, 1554, 1625 United States Preventative Task Force, 1428 Tubo-ovarian abscess (TOA), 533, 1437–1438 United States Preventive Services Task Force (USPSTF), Tubulointerstitial injury, 1281–1283 74, 75, 77 Tubulovillous, 1201 University Group Diabetes Program (UGDP) Tumor, node, metastasis (TMN), 1207 Study, 1662 Turf toe, 1512 Unresectable disease, 1164 Turner syndrome, 1707 Unstable angina, 974 Turtle sign, 186 Upper airway cough syndrome (UACS), 1073–1074 Twin Cycle Hypothesis, 1650 Upper gastrointestinal (UGI) bleeding Index 1863

causes of, 1137 Vaccine Information Statement (VIS), 75 diagnosis and management, 1137–1138 Vaccine preventable infections, 133 Upper motor neuron, 1458 Vaccine-preventable diseases, 74 Upper respiratory tract infections (URTIs) Vaccines, 515, 571, 876, 1367 acute bacterial rhinosinusitis (ABRS), 242 Vacuum deliveries, 188 acute otitis media, 245–246 Vaginal breech delivery, 179–181 croup, 246 Vaginal dryness, 1382, 1388 group A streptococcus pharyngitis, 245 Vaginitis, 1352–1353 respiratory syncytial virus infections, 246 Valacyclovir, 540 ® Up–To–Date , 1765 Valley fever, 1096 Uremic neuropathy, 869 Valproic acid (Depakene), 762, 853, 858 Ureteropyelograms, 1327 Value-based Payment (VBP), 64 Ureteroscopy, 1329 Value-based purchasing, 1788 Urge incontinence, 320 Values of family medicine, 1787 Uric acid, 1330, 1713 Valvular heart disease, 844, 1005 Urinary albumin, 1287 Valvular vegetation, 1055 Urinary calcium, 1330 Vancomycin, 1147 Urinary incontinence, 197, 320–322 Vardenafil, 1298 Urinary oxalate, 1330 Varenicline, 108 Urinary tract infections (UTIs), 154 Variant of unknown significance, 211 acute uncomplicated lower UTI, young women, Varicella, 84, 248 1247–1248 Varicella zoster vaccine, 867 acute uncomplicated pyelonephritis, 1248 Varicella zoster virus (VZV), 248 bacteriuria, 1250 Varicocele, 1322 CAUTI, 1249 Varnicline, 1081 in children, 1246 Vas deferens, 1318 chronic UTIs, 1249–1250 Vasa previa, 181 complicated UTI, 1248–1249 Vascular anomalies, 956 definition, 1245 Vascular dementia, 341, 342 fungal UTI, 1250 Vascular endothelial growth factor (VEGF), 1447 imaging evaluation, 1246–1247 Vascular malformations, 846 management, 1247 Vasculitis, 862, 1745 in pregnancy, 1247 Vasectomy, 1347 pyuria, 1250 bleeding, 1317 recurrent cystitis, 1248 complications, 1316–1317 spinal cord injuries, 1250 contraindications, 1317 urinalysis and culture, 1246 infection risk, 1317 urine culture, 1251 post-operative care, 1318 in younger men, 1249 reimbursement, 1316 Urine cytology, 1326 Vasoconstrictor, 957 Urine drug screen, 443, 760 Vasodilator, 1069 Urine drug screening (UDS), 794–795 Vasomotor symptoms (VMS), 1384, 1388 Urokinase, 843 Vasopressor therapy, 558 Urolithiasis, 1327–1331 Vassopressin, 1705 Urosepsis, 1329 Vegan, 106 Urothelial cancer, 1326–1327 Vegetarian, 106 Urticaria, 1238, 1576–1578 Veldman criteria, 1551 US Selected Practice Recommendations for Venereal Disease Research Laboratory (VDRL), 535 Contraceptive Use (US SPR), 1337 Venlafaxine, 1390 Usability, 1761, 1763 Venography, 1045 USPSTF, 1204 Venous lake, 1614 Uterine abnormalities, 1449–1450 Venous occlusive retinal disease, 920 Uterine atony, 183 Venous stasis syndrome, 1042 Uterine rupture, 178, 180 Venous thromboembolic disease, 1345 Venous thromboembolism (VTE), 157–158, 1278, 1389 clinical prediction rules, 1043–1044 V diagnosis, 1042–1046 Vaccination, 511–512 epidemiology, 1042 Vaccination during pregnancy, 197 management of, 1046–1048 1864 Index

Venous thromboembolism (VTE) (cont.) VLDL-P, 1638 pathophysiology, 1041–1042 Vocal hygiene, 956 prevention, 1049 Voice, 954, 956 Ventilation, 218 Voiding diaries, 1297 Ventilation-perfusion (V/Q) scanning, 1045 Volume depletion, 1253–1255 Ventilator associated lung injury (VALI), 1112 Volume excess, 1255–1256 Ventilator associated pneumonia (VAP), 1086 Von Willebrand’s disease (vWD), 1734–1736 Ventricular arrhythmias (VA), 997–999 VQ scan, 157 Ventricular assist devices, 1066 Vulvar intraepithelial neoplasia (VIN), 1367 Ventricular dyssynchrony, 1024 Vulvar intraepithelial neoplasm, 1611 Ventricular fibrillation (VF), 998–999, 1062 Vulvar SCC, 1609, 1611 Ventricular tachycardia (VT), 997–998, 1035, 1061, 1062 Vulvodynia, 1362 Verapamil, 858 Vulvovaginal atrophy, 1385 Vernal keratoconjunctivitis, 895 Vulvovaginal candidiasis (VVC), 1356 Verruca vulgaris, 1592 complicated VVC, 1357 Vertical mattress suture, 642 diagnosis of, 1357 Vertical transmission, 1591 treatment of, 1357 Vesicle, 539 Vulvovaginal lesions, 1626 Vesicular & pustular exanthems, 248 Vestibulitis, 1362 Vibratory urticaria, 1577 W Vibrio vulnificus, 1235 Waist, 702 Victim and culprit, 1496 Waist circumference, 107 Video-assisted thoracoscopic surgery, 1117, 1118 Wandering behaviors, 344 Video-EEG monitoring, 833 Warfarin, 1048 Violence, 89 Water deprivation test, 1705 Viral conjunctivitis, 892–894 Watershed ischemia, 838 Viral croup, 246 Wegener’s granulomatosis, 483, 1277 Viral cultures, 509 Weight loss, 80, 700, 1160 Viral exanthems, 246, 249 Well child visits, 44 Viral gastroenteritis, 1235 Wenckebach, 997 Viral hepatitis, 154–155 Wen/pilar cyst, 1617 Viral infections Wernicke’s encephalopathy, 870 incidence, 508 Western blot, 573 pathophysiology, 508–509 Wet mount, 1352 viral cultures, 509 Whiff test, 1353–1355 Viral pneumonia Whiplash, 1468 epidemiology, 1091 Whiplash associated disorders, 1468 family and community issues, 1092 Whipple’s triad, 1712 history, 1091 WHO analgesic ladder, 328 physical examination, 1091 WHO medical eligibility criteria, 198 transmission, 1091 Whooping cough, 244 treatment, 1091 Wickham’s striae, 1626 Viral URI, 243 Widespread pain index, 1547 Viral warts, 1592 Wilms tumor, 1290–1291 Virchow’s node, 1163–1164 Wilson’s disease, 853 Virilization, 1707–1708 Withdrawal time, 1205 Virtual colonoscopy, 1206 Wolf-Parkinson-White (WPW) Syndrome, 996 Visceral abdominal pain, 1212 Wolman’s disease, 1640 Vital exhaustion, 452 Women, 674–675 Vitamin B6 (Pyridoxine) deficiency, 870 Women’s Health Initiative (WHI), 1388, 1427 Vitamin B12 deficiency, 858, 870, 1695–1696, 1729–1730 Wood’s lamp, 1624 Vitamin D deficiency, 105, 231, 1688–1689, 1693–1695, Word catheter, 1365 1709 Worker’s compensation (WC), 583–584 Vitamin D supplementation, 1208 World Organization of Family Doctors (WONCA), 6 Vitamin E deficiency, 870 World Tourism Organization, 113 Vitamin K deficiency, 1738 World Wide Web, 1766 Vitiligo, 1624 Wrist instability, 1481 Index 1865

X Yersinia enterocolitica, 1145 Xanthelasmas, 1640 Yoga, 107, 419, 1550, 1779 Xerostomia, 953–954 Young adulthood stage, 20–21 evaluation and diagnosis, 954 medications, 954 pathophysiology, 953–954 Z principles, 953 Z score, 1687 treatment, 954 Zanamivir, 513 Zieman’s technique, 1225 Y Zinc oxide, 1621 Yeast, 1594–1595 Ziprasidone, 853 Yeast infection, 1356 Zollinger-Ellison syndrome, 1136 Yellow fever vaccination, 115 Zoster, 84 Yersinia, 1142 Zygapophyseal joint, 1462