DOCSLIB.ORG

NEWSLETTER VOLUME 32, NUMBER 3 Science Funding Included in U.S

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
NEWSLETTER VOLUME 32, NUMBER 3 Science Funding Included in U.S ASCB M A R C H 2 0 0 9 NEWSLETTER VOLUME 32, NUMBER 3 Science Funding Included in U.S. Celebrating Darwin Stimulus Plan Page 2 There is disagreement in the halls of the U.S. Bethesda campus. During Senate debate on the Congress about many of the provisions of the bill, NIH champions Senators Arlen Specter economic stimulus plan recently approved (R-PA) and Tom Harkin (D-IA) offered an by Congress and signed into law by U.S. amendment to the Senate bill to increase the Exploring President Obama. There appears to be no NIH funding in the bill. The amendment Unconscious disagreement, however, that federally funded would have provided the NIH with $10 science will play an important role in reviving billion: $9.2 billion for research and $800 Bias the ailing U.S. economy. million for capital equipment purchases and Page 11 NIH building renovations. The final version National Institutes of Health of the plan, signed into law by the President, The National Institutes of Health (NIH) is the provides the NIH with $8.2 billion for federal science program that will see the biggest research, $1 billion for renovating university Careers in benefit from the stimulus bill. The House research facilities around the U.S., $300 version and the original draft of the Senate million for the purchase of instrumentation Patent Law version of the stimulus plan both provided and other research equipment, and $500 Page 15 the NIH with $3.5 billion, to be spent over million for the construction, improvement, two years, for research, lab renovation, and and repair of NIH buildings and facilities. the renovation of buildings on the NIH’s Science Funding, continued on page 5 Inside Changes Align ASCB Did You Programs with Resources President’s Column 2 Programs begun with high hopes leave behind sadness when they Know...? Public Policy Briefing 5 must be suspended. Similarly, saying farewell to staff due to funding constraints is always difficult. As reported in the February 2009 March 31 is the ASCB Profile 6 ASCB Newsletter, the ASCB Council had tough decisions to make deadline for nomination about cutting expenses in light of declining market returns. Those submissions for seven InCytes from MBC 10 decisions included: ASCB awards—all of n Suspending development of the ASCB Image & Video Library, which will be presented at WICB Column 11 BioEDUCATE, CellBASE, and concept question repository digital the 2009 ASCB Annual resources (These sites are still available for use, but the ASCB Meeting in San Diego, Call for Nominations 14 cannot accept submissions at this time. The Society is seeking CA, December 5–9. For information on Dear Labby 15 funding to support future development of these resources.) n Implementing layoffs of staff eligibility and submission Half-Century Fund Donors 16 n Discontinuing production of the ASCB Annual Meeting requirements, see “Call Abstracts CD-ROM (All abstracts will remain searchable online for Nominations” on Members in the News 16 and will remain available for referencing.) p.14 or go to www.ascb. n Eliminating the mailing of the ASCB Annual Meeting Program org and click on “Awards/ Member Gifts 16 Book to pre-registrants (This not only cuts a significant expense, Grants.” and furthers ASCB “green” efforts, it allows for a September Please take the time Letters to the Editor 17 regular submission deadline, otherwise impossible given the early to nominate a deserving date of the 2009 ASCB Annual Meeting. The Program Book will colleague, postdoc, Grants & Opportunities 18 be available online as a searchable PDF before the meeting, and mentor, or student. n Calendar 20 printed copies will be distributed onsite.) n —Joan Goldberg The American Society for Cell Biology PRESIDENT’S Column 8120 Woodmont Avenue, Suite 750 Bethesda, MD 20814-2762, USA Tel: (301) 347-9300 Fax: (301) 347-9310 Celebrating Darwin and the [email protected], www.ascb.org Joan R. Goldberg Scientific Method Executive Director The year 2009 marks the 200th anniversary Curiosity and wonder at the everyday world Officers of the birth of Charles Darwin, whose ideas were hallmarks of Darwin’s mind. He never and writings revolutionized biology. They were seemed to stop asking questions! Importantly, Brigid Hogan President radical and far-reaching. And they continue to his curiosity was coupled with both careful Timothy J. Mitchison President-Elect resonate through every branch observation and a tenacious Bob Goldman Past President Thoru Pederson Treasurer of natural science, not least of drive to test ideas. He studied Jean E. Schwarzbauer Secretary all cell biology. So, as a society, barnacles, beetles, butterflies, let’s cell-ebrate Darwin, and try birds, climbing plants, Council to follow his great example. insect-eating plants, orchids, earthworms, seeds, pigeons, and Pascale Cossart domesticated animals… the Susan K. Dutcher Celebrating an D. Scott Emr Inspiration list goes on and on. He drew Joan R. Goldberg, ex officio There are many sources from on a worldwide network of Holly V. Goodson which to draw inspiration fellow naturalists, experts, and Kathleen J. Green about Darwin in the coming laypeople to supply him with Paul W. Sternberg specimens and information. He Elizabeth Sztul year (see, for example, had close friends and colleagues Clare M. Waterman www.darwin200.org; www. Fiona M. Watt darwin2009.cam.ac.uk; www. Brigid Hogan who advocated his ideas. Susan R. Wente nature.com/news/specials/ Curiosity, experimentation, Susan M. Wick darwin; and www.sciencemag.org/darwin). communication, and community… all Virginia A. Zakian Some contributions highlight the very latest characteristics that we strive to emulate. The ASCB Newsletter advances in evolutionary research and their is published 12 times per year application to fields such as social behavior Communicating What Science Is by The American Society I remember that the parts of On the Origin of for Cell Biology. and medicine. Others reach out to the general public. These will help to address the gap Species that I enjoyed the most as a high school Joan R. Goldberg Editor between Darwin’s stature among scientists student were the descriptions of the experiments W. Mark Leader Editor and the way in which he is perceived by large that Darwin had carried out almost in his Elizabeth M. Rich Production Manager numbers of people in our communities. own “backyard.” For example, to test his ideas Kevin Wilson Public Policy Director about the geographic dispersal of seeds, he Ed Newman Advertising Manager It is no news to any of us today that John Fleischman Science Writer evolution and science have been under siege. asked how long seeds and fruits could survive Thea Clarke Editorial Manager I remember being astounded not long after I being immersed in seawater or being fed to came to the U.S. to hear Darwin referred to as animals; he questioned how many could be one of the Four Horsemen of the Apocalypse on germinated from dried earth found stuck on Deadlines for submission of a religious TV station! Surely this was not the dead migratory birds. The take-home message articles and advertising for me as a youngster was that one doesn’t materials: same Charles Darwin as the gentleman hero I had revered since high school? need fancy equipment to think and act like a Issue Deadline Today, I still have a picture of Darwin scientist. The important values are curiosity and April March 1 on my desk; and I still find inspiration from experimentation, and conclusions based on data May April 1 his example. Like all of us, I deeply admire and logical analysis. If we fail to communicate June May 1 his insatiable curiosity and his ability to the importance of data-driven scientific inquiry ASCB Newsletter communicate his ideas to a wide audience. I to our elected officials, nonscientific colleagues, ISSN 1060-8982 have particular admiration for his courage in friends, neighbors, and the public, then we Volume 32, Number 3 fail to live up to Darwin’s example. We must March 2009 holding to his beliefs even though he knew they would be unpopular. I hope that as scientists, continue to press for the application of the © 2009 teachers, and mentors, we can pass along to scientific method to the urgent problems that The American Society for Cell Biology future generations not only the fundamental face our society. Postmaster: Send change of address to principles of evolution and natural selection, Scientists—and the ASCB—have an ASCB Newsletter The American Society for Cell Biology but also the essence of Darwin’s great mind and obligation. As many of you know, the ASCB is 8120 Woodmont Avenue, Suite 750 very active in promoting the public understanding Bethesda, MD 20814-2762, USA personality. 2 ASCB NEWSLETTER MARCH 2009 of science. The celebrations of the 200th resources to help you teach your students. anniversary of Darwin’s birth provide a great The ASCB BioEDUCATE website links to opportunity to promote not only sites showcasing evolution. Our a greater public understanding education journal CBE—Life of evolution, but of scientific Sciences Education (www.lifescied. concepts in general. By the org), published online four times time you read this, we will be a year, features numerous articles celebrating a substantial increase about teaching evolution. The Annual in U.S. funding for science in spring issue, online as of March 2, general, and for the NIH budget features a timely look at Darwin- Meeting in particular. However, we need related Web resources. And our to make our voices heard about Education Committee, under the how the money should be best able leadership of Chair Caroline Lost & spent. The next issue of this Kane, is working on new sessions Newsletter will highlight how the for educators at the next ASCB Found funds will be spent.
Load more

Recommended publications
  • ANNUAL REVIEW 1 October 2005–30 September
    WELLCOME TRUST ANNUAL REVIEW 1 October 2005–30 September 2006 ANNUAL REVIEW 2006 The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. It funds innovative biomedical research, in the UK and internationally, spending around £500 million each year to support the brightest scientists with the best ideas. The Wellcome Trust supports public debate about biomedical research and its impact on health and wellbeing. www.wellcome.ac.uk THE WELLCOME TRUST The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. 123 CONTENTS BOARD OF GOVERNORS 2 Director’s statement William Castell 4 Advancing knowledge Chairman 16 Using knowledge Martin Bobrow Deputy Chairman 24 Engaging society Adrian Bird 30 Developing people Leszek Borysiewicz 36 Facilitating research Patricia Hodgson 40 Developing our organisation Richard Hynes 41 Wellcome Trust 2005/06 Ronald Plasterk 42 Financial summary 2005/06 Alastair Ross Goobey 44 Funding developments 2005/06 Peter Smith 46 Streams funding 2005/06 Jean Thomas 48 Technology Transfer Edward Walker-Arnott 49 Wellcome Trust Genome Campus As at January 2007 50 Public Engagement 51 Library and information resources 52 Advisory committees Images 1 Surface of the gut. 3 Zebrafish. 5 Cells in a developing This Annual Review covers the 2 Young children in 4 A scene from Y fruit fly. Wellcome Trust’s financial year, from Kenya. Touring’s Every Breath. 6 Data management at the Sanger Institute. 1 October 2005 to 30 September 2006. CONTENTS 1 45 6 EXECUTIVE BOARD MAKING A DIFFERENCE Developing people: To foster a Mark Walport The Wellcome Trust’s mission is research community and individual Director to foster and promote research with researchers who can contribute to the advancement and use of knowledge Ted Bianco the aim of improving human and Director of Technology Transfer animal health.
    [Show full text]
  • CRISPR-Cas9 a New Tool for Genome Editing.Pdf
    CRICRICRISSPSPEPERERRCCCaasas9s99 AA ANe Ne Neww wT To Toool olf olf orf orGe rGe Gennonomomem eE eEd Editdiitinitngingg ByB JyBen Jyen Jneninferinfer iDofer Do uDodunduand,a nK, aeK,v eKivnei nvDi noD xoDzxoezxnez,n ea,n a,d na dMn dMa rMatirnati rnJti nJie nJkienkek A AK eAKy eK yEe xEyp xEepxrepimreimenriment enpt rpto rpdorudocudecudec dbe ydb Tyb hTye hT eEh xeEp xElpoxlrpoelrore’srre ’Gsr ’uGs iuGdieud ietdo et oB t ioBo ilBooilgooylgoygy 2 The Explorer’s Guide to Biology https://explorebiology.org/ CRISPR-Cas9 A New Tool for Genome Editing Jennifer Doudna, Kevin Doxzen, and Martin Jinek Jennifer Doudna Jennifer Doudna is a professor in the Departments of Molecular and Cell Biology and the Chemistry and Chemical Engineering at the University of California, Berkeley. For her studies on CRISPR-Cas9, Dr. Doudna has received several awards including the Breakthrough Prize in the Life Sciences, the Japan Prize, and the Canada Gairdner Award. She has been leading efforts to discuss ethical uses of genome editing technologies. Doudna teaches in Bio 1A, an introductory biology class at UC Berkeley. Kevin Doxzen Kevin Doxzen, a former graduate student with Jennifer Doudna, is a sci- ence communications specialist at the Innovative Genomics Institute, which is advancing genome engineering using CRISPR technologies. 3 Martin Jinek Martin Jinek, born in Czechoslovakia and a former postdoctoral fellow with Jennifer Doudna, is now an associate professor in the Department of Biochemistry at the University of Zurich. Jinek received the EMBL John Kendrew Young Scientist Award and the Friedrich Miescher Award of the Swiss Society for Molecular and Cellular Biosciences.
    [Show full text]
  • Download This Issue As A
    MICHAEL GERRARD ‘72 COLLEGE HONORS FIVE IS THE GURU OF DISTINGUISHED ALUMNI CLIMATE CHANGE LAW WITH JOHN JAY AWARDS Page 26 Page 18 Columbia College May/June 2011 TODAY Nobel Prize-winner Martin Chalfie works with College students in his laboratory. APassion for Science Members of the College’s science community discuss their groundbreaking research ’ll meet you for a I drink at the club...” Meet. Dine. Play. Take a seat at the newly renovated bar grill or fine dining room. See how membership in the Columbia Club could fit into your life. For more information or to apply, visit www.columbiaclub.org or call (212) 719-0380. The Columbia University Club of New York 15 West 43 St. New York, N Y 10036 Columbia’s SocialIntellectualCulturalRecreationalProfessional Resource in Midtown. Columbia College Today Contents 26 20 30 18 73 16 COVER STORY ALUMNI NEWS DEPARTMENTS 2 20 A PA SSION FOR SCIENCE 38 B OOKSHELF LETTERS TO THE Members of the College’s scientific community share Featured: N.C. Christopher EDITOR Couch ’76 takes a serious look their groundbreaking work; also, a look at “Frontiers at The Joker and his creator in 3 WITHIN THE FA MILY of Science,” the Core’s newest component. Jerry Robinson: Ambassador of By Ethan Rouen ’04J, ’11 Business Comics. 4 AROUND THE QU A DS 4 Reunion, Dean’s FEATURES 40 O BITU A RIES Day 2011 6 Class Day, 43 C L A SS NOTES JOHN JA Y AW A RDS DINNER FETES FIVE Commencement 2011 18 The College honored five alumni for their distinguished A LUMNI PROFILES 8 Senate Votes on ROTC professional achievements at a gala dinner in March.
    [Show full text]
  • Vol 9 No 1 Spring
    A PUBLICATION OF THE AMERICAN SOCIETY FOR MATRIX BIOLOGY SPRING 2010, VOLUME 9, NO. 1 President’s Letter Expanding the Society’s Value to You and Your Role in the Society Since its inception in 2001, the principal function of the ASMB has been to organize the OFFICERS biennial meeting. The value of this meeting to our members cannot be understated. The ASMB meeting has emerged as the matrix-centric President: meeting in North America, and it provides an William Parks (2010) open venue for students, postdocs, fellows, and junior faculty to present their work and to inter- act with established investigators. Speaking for Vice Pres/President Elect myself, I very much look forward to the ASMB Jean Schwarzbauer (2010) meeting, not only because I get to see many Bill Parks friends, but also to hear a lot of incredibly good science. This year’s meeting will be no excep- Past President: tion and promises to be truly outstanding. I applaud Jean Schwarzbauer and the Renato Iozzo (2010) rest of the Program Committee for putting together an exciting meeting loaded with interesting topics and great speakers (please check out the program here). By organizing the meeting, ASMB provides value to you, the membership, but I Secretary/Treasurer think we–the Society–should always be looking to do more; that is, to provide more Joanne Murphy-Ullrich (2011) bang for your dues buck. For this year’s meeting, we have expanded the Travel Awards that will be given to trainees in recognition of outstanding research, and we recently established merit-based Minority Scholarships that will be awarded to eli- Council Members gible students and postdocs.
    [Show full text]
  • Nobel Laureates Endorse Joe Biden
    Nobel Laureates endorse Joe Biden 81 American Nobel Laureates in Physics, Chemistry, and Medicine have signed this letter to express their support for former Vice President Joe Biden in the 2020 election for President of the United States. At no time in our nation’s history has there been a greater need for our leaders to appreciate the value of science in formulating public policy. During his long record of public service, Joe Biden has consistently demonstrated his willingness to listen to experts, his understanding of the value of international collaboration in research, and his respect for the contribution that immigrants make to the intellectual life of our country. As American citizens and as scientists, we wholeheartedly endorse Joe Biden for President. Name Category Prize Year Peter Agre Chemistry 2003 Sidney Altman Chemistry 1989 Frances H. Arnold Chemistry 2018 Paul Berg Chemistry 1980 Thomas R. Cech Chemistry 1989 Martin Chalfie Chemistry 2008 Elias James Corey Chemistry 1990 Joachim Frank Chemistry 2017 Walter Gilbert Chemistry 1980 John B. Goodenough Chemistry 2019 Alan Heeger Chemistry 2000 Dudley R. Herschbach Chemistry 1986 Roald Hoffmann Chemistry 1981 Brian K. Kobilka Chemistry 2012 Roger D. Kornberg Chemistry 2006 Robert J. Lefkowitz Chemistry 2012 Roderick MacKinnon Chemistry 2003 Paul L. Modrich Chemistry 2015 William E. Moerner Chemistry 2014 Mario J. Molina Chemistry 1995 Richard R. Schrock Chemistry 2005 K. Barry Sharpless Chemistry 2001 Sir James Fraser Stoddart Chemistry 2016 M. Stanley Whittingham Chemistry 2019 James P. Allison Medicine 2018 Richard Axel Medicine 2004 David Baltimore Medicine 1975 J. Michael Bishop Medicine 1989 Elizabeth H. Blackburn Medicine 2009 Michael S.
    [Show full text]
  • The Nobel Foundation Annual Review 2018
    THE NOBEL FOUNDATION ANNUAL REVIEW • 2018 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 1 1901 WILHELM CONRAD RÖNTGEN The first Nobel Prize in Physics was awarded to Wilhelm Conrad Röntgen for his discovery of X-radiation. The X-ray tube pictured on the cover is on display at the Nobel Prize Museum. Photo: Alexander Mahmoud 2018 BERNICE A. KING “I wish to commend the Nobel Museum for (…) this new exhibition. I believe that my parents’ message of social justice and equality is as important today as ever before.” The exhibition A Right to Freedom - Martin Luther King, Jr. was inaugurated by King’s daughter Bernice A. King at the Nobel Prize Museum on 28 September 2018. Photo: Alexander Mahmoud 2 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 3 For the greatest beneft to humankind ALFRED NOBEL 4 THE NOBEL FOUNDATION · ANNUAL REVIEW 2018 “I can tell you how. It is very easy. The first thing you must do is to have great teachers.” Paul A. Samuelson, 1970 Laureate in Economic Sciences, on how to earn a Nobel Prize. obel Laureates often Luther King, Jr., and with a Nobel Prize attest to how crucial Teacher Summit on the theme Teach their teachers have been. Love and Understanding, with 350 Teachers, researchers and teachers from 15 countries attending. others who contribute Al Gore, the 2007 Peace Prize Lars Heikensten, Executive Director Nto increased knowledge are the heroes Laureate, addressed How to Solve the of the Nobel Foundation since 2011. and heroines of our age. When the very Climate Crisis when he spoke at the 2018 Photo: Kari Kohvakka idea of science is being questioned, our Nobel Peace Prize Forum in Oslo.
    [Show full text]
  • SAC 2014 Celebration of Science Book
    Fostering Innovation at MGH Poster Session Abstracts 67th Annual Meeting of the MGH Scientific Advisory Committee Celebration of Science The MGH Research Institute: Meeting the Challenges that Lie Ahead April 2 & 3, 2014 Simches Auditorium 185 Cambridge Street, 3rd Floor Management Management ECOR Administrative Offices | 50 Staniford Street, 10th Floor | Boston, MA 02114 | [email protected] Fostering Mainstay Mainstay Innovation of MGH of MGH at MGH Management Innovation Management Innovation Welcome elcome to the 67th Annual Meeting of the MGH Scientific Advisory Committee (SAC) on April 2nd and 3rd, 2014. Dr. Richard Lifton has graciously agreed to W chair our SAC meeting again this year. As in past years, we will begin our two-day SAC meeting with a Celebration of Science at MGH. Our poster session begins at 11:00 am on Wednesday, April 2, followed by an afternoon Research Symposium from 2:00 pm to 5:00 pm. The outstanding MGH researchers who will be presenting their work in our Symposium this year are the 2014 Howard Goodman Award recipient Filip Swirski, PhD and the 2014 Martin Basic and Clinical Research Prize recipients, Jayaraj Rajagopal, MD, and Stephanie Seminara, MD. We are honored to have as our keynote speaker, Richard O. Hynes, PhD, from MIT. We will close the first day with a Reception for invited guests at the Russell Museum. On Thursday, April 3, Dr. Kingston will open the SAC meeting with an ECOR Report. After this report, Anne Klibanski, MD, Partners Chief Academic Officer, will give a presentation on the Integration of MGH Research to the Partners Enterprise.
    [Show full text]
  • The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008
    Journal of Visualized Experiments www.jove.com Video Article The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008 Roger Y. Tsien1 1 URL: https://www.jove.com/video/1575 DOI: doi:10.3791/1575 Keywords: Cellular Biology, Issue 35, GFP, Green Fluorescent Protein, IFPs, jellyfish, PKA, Calmodulin Date Published: 1/13/2010 Citation: Tsien, R.Y. The 2009 Lindau Nobel Laureate Meeting: Roger Y. Tsien, Chemistry 2008. J. Vis. Exp. (35), e1575, doi:10.3791/1575 (2010). Abstract American biochemist Roger Tsien shared the 2008 Nobel Prize in Chemistry with Martin Chalfie and Osamu Shimomura for their discovery and development of the Green Fluorescent Protein (GFP). Tsien, who was born in New York in 1952 and grew up in Livingston New Jersey, began to experiment in the basement of the family home at a young age. From growing silica gardens of colorful crystallized metal salts to attempting to synthesize aspirin, these early experiments fueled what would become Tsien's lifelong interest in chemistry and colors. Tsien's first official laboratory experience was an NSF-supported summer research program in which he used infrared spectroscopy to examine how metals bind to thiocyanate, for which he was awarded a $10,000 scholarship in the Westinghouse Science Talent Search. Following graduation from Harvard in 1972, Tsien attended Cambridge University in England under a Marshall Scholarship. There he learned organic chemistry --a subject he'd hated as an undergraduate-- and looked for a way to synthesize dyes for imaging neuronal activity, generating BAPTA based optical calcium indicator dyes. Following the completion of his postdoctoral training at Cambridge in 1982, Tsien accepted a faculty position at the University of California, Berkeley.
    [Show full text]
  • Nov. Issue of ASCB Newsletter
    ASCB NOVEMBER 2010 NEWSLETTER VOLUME 33, NUMBER 10 Improving Submit Images to Work–Life Satisfaction The Cell: An Image Library Page 15 Published Images and Videos Accepted To further discovery and education, the ASCB’s repository for cellular images and videos accepts Are You First published and unpublished work. According to Caroline Kane, the PI for The Cell: An Image Author or Last? Library, “This new repository of cell images is expertly reviewed and annotated to provide a valuable resource for researchers, educators, and the general public. Access to the database is Page 21 free and open. The Cell aims to advance research and, ultimately, have a positive impact upon human health and education.” The Cell’s expanded licensing options for contributors and users will promote faster growth and enhanced usefulness. The Cell is available as a repository for images in published articles Cell Biology and supplementary materials. It can also serve as an archive for additional images and movies Italian Style that helped lead to discovery. Page 23 Understanding Distribution Rights The Cell welcomes unpublished and previously published images, but contributors must have the distribution rights. Many publishers, like the ASCB, which publishes Molecular Biology of the Cell, allow authors to retain copyright. However, publishers may nevertheless limit distribution Inside of the work. Limitations may relate to intended use (commercial and/or educational), alteration, and attribution. Authors should confirm the distribution rights before selecting the appropriate Public Policy Briefing 3 option when contributing to The Cell. Contributors with appropriate distribution rights might select a public domain license. Annual Meeting Program 6 This license is appropriate for those who own copyright without limitations as well as for those Networking at Annual Meeting 11 submitting images or videos where all authors are U.S.
    [Show full text]
  • Download Ps Nobel Prizes for Site BEE 11.18.16 Revised 11.30.17.Pdf
    Nobel Laureates at the College of Physicians and Surgeons For years, College of Physicians and Surgeons alumni, faculty, and researchers have led groundbreaking clinical and basic scientific studies that have transformed our understanding of human biology and advanced the practice of medicine. On many occasions, this work has been honored with the Nobel Prize. The scope of research led by P&S Nobel laureates is tremendous. Although most of our prizewinners were honored for work in physiology or medicine, a few also received the prize for chemistry. Their research has fundamentally shaped the course of numerous fields, including cardiology, neuroscience, genetics, pharmaceutical development, and more. Our Nobel laureates include: André Cournand and Dickinson Richards (P&S’23), whose work at P&S on cardiac catheterization—a method of inserting a tiny tube into the heart—provided the basis for open-heart surgery and interventional cardiology Baruch Blumberg (P&S’51), who discovered the hepatitis B virus and helped develop a test and a vaccine for the virus Joshua Lederberg, a Columbia College and P&S graduate student who showed that bacteria can exchange genes when they reproduce, creating a way to model and study genetics in higher organisms Harold Varmus (P&S’66), who demonstrated how genes in normal human and animal cells can mutate to cause cancer, leading to a new generation of research on the genetic origins of cancer Eric Kandel, current University Professor, who showed how memories are stored in nerve cells, greatly enhancing
    [Show full text]
  • Hhmi Bulletin 3 4 Hhmi Club
    HHMI BULLETIN 4000 Jones Bridge Road • Chevy Chase, Maryland 20815-6789 Howard Hughes Medical Institute www.hhmi.org One Lump or Two? in this issue Once again, those fast-growing yeast find a way to turn a The Silicon Marvel long-held theory on its head. This time, it’s about prions, • Prions for Good which aren’t as universally nasty as once suspected. Some may actually help organisms evolve. The yeast colony shown here www.hhmi.org A Kaleidoscopic View contains a protein in its prion form. Because the prion, known as PSI+, is self-replicating and forms fibrous amyloids, the yeast look lumpy and bumpy—strikingly different from normally smooth yeast. Susan Lindquist’s group has found 19 yeast proteins that can switch back and forth between a normal and a prion version. The prions are thought to help the yeast adapt to changing conditions (see “A Silver Lining,” page 22). LIGHT MOVES v ol. 23 Heather True / Lindquist lab /no. 02 O b s e r v a t i O n s 16 Secret Agent MAn Skin cells do more than just cover our bodies. As a neurology resident, Stanley Prusiner saw Creutzfeldt–Jakob agent began to emerge. These data established, for the first time, that Keratinocytes, for example, anchor immune cells disease kill a patient in a matter of months. Researchers knew the rare a particular macromolecule was required for infectivity and that this within the epidermis, move and proliferate during neurodegenerative disease and scrapie, a similar disease in sheep, macromolecule was a protein …. wound healing, and even secrete inhibitory molecules were infectious but not as a result of a typical virus.
    [Show full text]
  • A REVOLUTION in the PHYSIOLOGY of the LIVING CELL FUTURE ANNUAL MEETINGS of by Gilbert N
    A REVOLUTION IN THE PHYSIOLOGY OF THE LIVING CELL FUTURE ANNUAL MEETINGS OF by Gilbert N. Ling Orig. Ed. 1992 404 pp. $64.50 THE AMERICAN SOCIETY FOR ISBN 0-89464-398-3 CELL BIOLOGY The essence of a major revolution in cell physiology -the first since the cell was recognized as the basic unit of life a century and a half ago - is presented and altemative theories are discussed in this text. Although the conventional mem- brane-pump theory is still being taught, a new theory of the living cell, called the association-induction hypothesis has been proposed. It has successfullywfthstood 1995 twenty-five years of worldwide testing and has already generated an enhancing DC diagnostic tool ofgreat power, magnetic resonance imaging (MRI).This volume is Washington, intended forteachers, students and researchers ofbiology and medicine. December 9-13 i't...a correct basic theory of cell physiology, besides its great intrinsic value in mankind's search forknowledge aboutourselves and the world we live in, willalso play a crucial role in the ultimate conquest of cancer, AIDS, and other incurable 1996 diseases.'-from the Introduction. ASCB Annual Meeting/ on Cell Biology t When ordering please add t".Ling turns cellphysiology upside down. He Sixth International Congress $5.00 first bookl$1.50 each ad- practicallyredefines the cell. He provides com- San Francisco, California ditional book to cover shipping pellingevidencefor headequacyofhis theoryn December 7-11 charges. Foreign shipping costs evidence that cannot fail to impress even the available upon request. most extreme skeptics....'- Gerald H. Pollock, _ Ph.D., Univ. ofWashington.
    [Show full text]