DOCSLIB.ORG

ANNUAL REVIEW 1 October 2005–30 September

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
ANNUAL REVIEW 1 October 2005–30 September WELLCOME TRUST ANNUAL REVIEW 1 October 2005–30 September 2006 ANNUAL REVIEW 2006 The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. It funds innovative biomedical research, in the UK and internationally, spending around £500 million each year to support the brightest scientists with the best ideas. The Wellcome Trust supports public debate about biomedical research and its impact on health and wellbeing. www.wellcome.ac.uk THE WELLCOME TRUST The Wellcome Trust is the largest charity in the UK and the second largest medical research charity in the world. 123 CONTENTS BOARD OF GOVERNORS 2 Director’s statement William Castell 4 Advancing knowledge Chairman 16 Using knowledge Martin Bobrow Deputy Chairman 24 Engaging society Adrian Bird 30 Developing people Leszek Borysiewicz 36 Facilitating research Patricia Hodgson 40 Developing our organisation Richard Hynes 41 Wellcome Trust 2005/06 Ronald Plasterk 42 Financial summary 2005/06 Alastair Ross Goobey 44 Funding developments 2005/06 Peter Smith 46 Streams funding 2005/06 Jean Thomas 48 Technology Transfer Edward Walker-Arnott 49 Wellcome Trust Genome Campus As at January 2007 50 Public Engagement 51 Library and information resources 52 Advisory committees Images 1 Surface of the gut. 3 Zebrafish. 5 Cells in a developing This Annual Review covers the 2 Young children in 4 A scene from Y fruit fly. Wellcome Trust’s financial year, from Kenya. Touring’s Every Breath. 6 Data management at the Sanger Institute. 1 October 2005 to 30 September 2006. CONTENTS 1 45 6 EXECUTIVE BOARD MAKING A DIFFERENCE Developing people: To foster a Mark Walport The Wellcome Trust’s mission is research community and individual Director to foster and promote research with researchers who can contribute to the advancement and use of knowledge Ted Bianco the aim of improving human and Director of Technology Transfer animal health. During 2005–2010, Facilitating research: To promote the our aims are: best conditions for research and the John Cooper use of knowledge Director of Resources Advancing knowledge: To support research to increase understanding Developing our organisation: To use David Lynn of health and disease, and its our resources efficiently and effectively. Head of Strategic Planning and Policy societal context Clare Matterson Using knowledge: To support the Director of Medicine, Society and development and use of knowledge History to create health benefit David Phillipps Engaging society: To engage with Director of Finance society to foster an informed climate Sohaila Rastan within which biomedical research Director of Science Funding can flourish John Stewart Head of Legal and Company Secretary Danny Truell Chief Investment Officer Other senior management Allan Bradley Director of the Wellcome Trust Sanger Institute Susannah Randall Head of Communications As at January 2007 Strategic Plan updates, summarising progress in achieving specific objectives during 2005/06, can be found at www.wellcome.ac.uk/strategicplan. DIRECTOR’S STATEMENT 2 WORKING WITH RESEARCHERS We are working to achieve ever closer relationships with the best researchers to fund work that will have important impacts in improving human and animal health. 1 23 This Annual Review illustrates some of Parkinson’s disease. Research we • Professors Austin Smith and Fiona the many ways in which the work we have funded has led to both national Watt were awarded £7 million to support or carry out ourselves is and international changes in health establish an international centre of making a difference. policy. The World Health Organization excellence in fundamental stem cell This year’s stories of the discovery and now recommends artemisinin research. The Wellcome Trust Centre application of new knowledge illustrate combination therapies for treatment for Stem Cell Research at the how outstanding researchers are of malaria and the Kenyan Ministry University of Cambridge will explore the gaining insight into biological processes of Health is continuing its Hib genetic and biochemical mechanisms at all scales, from the atomic structure immunisation programmes. that control how stem cells develop into particular types of cells. of medically important proteins to the Partnerships global impact and treatment of malaria. We can only achieve this kind of • Professors Ray Dolan and Karl Our understanding of the human impact through working closely with Friston, at the Wellcome Trust Centre genome continues to grow, with yet the research community. Through for Neuroimaging, University College another surprising discovery from the supporting the best people with the London, received an award of Wellcome Trust Sanger Institute – that best ideas and providing flexible £6.7m. This will enhance their genetic variation between individuals funding, we hope to support the research programme into the neural is far higher than previously thought. generation of new knowledge to basis of human cognition, work Genetics has benefited enormously underpin future discoveries and that is extending our understanding from high-throughput sequencing their subsequent application. of common neurological and and other technologies, which have psychiatric diseases, such as A key issue for all funding agencies is schizophrenia and dementia. transformed the way research is to balance bottom-up and top-down carried out. Structural biology is less approaches to the support of research. • Professor Paul Luzio received a easy to scale up, but the Structural Who drives the process of discovery? £4m award for the Cambridge Institute Genomics Consortium has made Who asks the research questions? for Medical Research. The Institute excellent progress in its production Is it the researchers or the funding explores the underlying molecular and of structures of medically important agencies? We take a flexible approach, cellular mechanisms behind disease proteins, and many valuable discoveries and have an open door for the best and it has led key research into how are being made about protein function researchers to bring us their best viruses evade our immune system, on the basis of structural information. ideas. However, we also work with genetic susceptibility to diabetes, and Such studies complement research the research community to identify progress towards novel treatments for into the threats to health we face in areas where there is unmet research Alzheimer’s and Huntington’s disease. this country and globally. The global need and to provide catalysis to ensure Our strategy will continue to create a impact of malaria, for example, is now that vital research is not overlooked. framework that can support, but not much clearer. Wellcome Trust-funded Last year we introduced Strategic constrain, those that look to us for researchers are world leaders in the Awards to ensure we could support funding. Our Strategy Committees fight against this insidious disease. the best ideas wherever they are found. are key to helping us identify our Application of new knowledge has The scope of these awards is really future research priorities and this year seen trials of new dipstick diagnostic only limited by the imagination of the we published an ‘à la carte’ menu of tests for trachoma, trials of new research community. This year we areas identified as important for vaccines and diagnostics for made our first three awards, providing future research activity. tuberculosis, and trials for new outstanding research groups with To ensure we can support the best treatments for the symptoms of significant and flexible support: people, our portfolio of careers DIRECTOR’S STATEMENT 3 HIGHLIGHTS OF THE YEAR schemes has been reviewed and as anticancer agents. Creative a number of new schemes were approaches to the discovery of new launched this year. The new Sir Henry medicines like this are vital to help Wellcome Postdoctoral Fellowship society address the growing burden Awards, worth £250 000 over of disease. four years, will allow researchers Improving healthcare for patients was unprecedented freedom early in their the aim of a further consortium formed careers to pursue their own research. this year. This consortium, led by the Our new Flexible Travel Awards will Wellcome Trust, provided £84m to also support collaboration-building and boost experimental medicine in the the transfer of ideas and skills through UK and the Republic of Ireland. This support for sabbaticals and travelling major investment aims to develop and fellowships. Other new initiatives were strengthen Clinical Research Facilities, also launched this year, notably the which bring together laboratory and £91m Seeding Drug Discovery clinical patient-based research in initiative, aiming to provide funding order to answer important questions • Whole-genome map uncovers for the early stages of drug discovery, about health and disease. Under the unexpectedly high levels of which often struggle to attract funding umbrella of the UK Clinical Research copy number variation. for commercial development. We hope Collaboration, this initiative brought this initiative will create a stronger together the major health research • Functional imaging reveals synergy between academia and charities, the government funding brain centres involved in industry and capitalise on the powerful bodies and health departments. decision-making. resources that are spread across the academic, biotechnology and A research funder’s work does not • Nanog identified as key pharmaceutical sectors. end
Load more

Recommended publications
  • The Business Bug Master’S Message College News
    Optima Fitzwilliam College Newsletter | Issue 17 | Spring 2011 The Catalan Connection | Solar Paint | Medics and Vets Reunion | The Business Bug Master’s message College News No reader of Optima can fail to be aware of the challenges now facing us. The government’s cutting of the teaching budget by 80% has Duke of Edinburgh opens implications even for Cambridge. A tuition fee of £9,000 will cover Library & IT Centre barely half the cost of educating a student here. His Royal Highness the Duke of Edinburgh KG KT, Chancellor of the University and Visitor of But this issue of Optima again the College, made his fifth visit to Fitzwilliam reminds us why we must sustain on 19 April 2010 to open the Library & IT our commitment to a collegiate Centre in the presence of benefactors, experience which is both Fellows, students and staff. The building intellectual and enriching in a wider Architects’ sense. It contains news items of featured on the cover of the importance, such as the completion Journal in March. of the modern Fitzwilliam in the shape of the formal opening of the This exciting new building, designed by new Library and IT Centre, while Edward Cullinan Architects, has recalling another historic moment – transformed the College’s academic our 1979 move to coeducation. provision and is popular with students. It refers to great public academic The Library features in the short film occasions such as the Foundation ‘The Perfect Desk’ commissioned by the Lecture. It underlines the University to show the role of college JET photographic JET international dimension of the libraries in the academic life of students.
    [Show full text]
  • A DNA Database in the NHS: Your Freedom up for Sale?
    A DNA database in the NHS: Your freedom up for sale? May 2013 In April 2013, the Caldicott Committee, including Government Chief Scientist Sir Mark Walport, proposed new rules for data-sharing which would allow the Government to build a DNA database of the whole population of England in the NHS by stealth.1 The plan is to make NHS medical records and people’s genetic information available to commercial companies and to use public-private partnerships to build a system where all private information about every citizen is also accessible to the police, social workers, security services and Government. The Wellcome Trust, which was involved in the Human Genome Project and was led by Walport for ten years, has produced a plan which involves including a variant file, containing the whole genome of every person minus the reference genome, as an attachment to every medical record in the NHS in England.2 This data would be made available to ‘researchers’ (including commercial companies) for data-mining in the cloud and personalised risk assessments would be returned to individuals. The aim is to transform the NHS in line with proposals developed more than a decade ago by former GlaxoSmithKline Chairman Sir Richard Sykes. This is expected to massively expand the market for medicines, medical tests and other products, such as supplements and cholesterol-lowering margarines, by allowing products to be marketed to individuals based on personal risk assessments, created using statistical analysis of genetic data, medical records and other health information. The proposal to build a DNA database in the NHS was endorsed by the Human Genomics Strategy Group in 20123,4 and the Government (led by Prime Minister David Cameron) has quietly adopted this recommendation without telling members of the public.
    [Show full text]
  • Holliday Junction Processing Enzymes in Eukaryotes. by Anthony John
    Holliday junction processing enzymes in eukaryotes. By Anthony John Keeley Thesis submitted to the University of London, for the degree of Doctor of Philosophy, September 1999 ProQuest Number: 10609126 All rights reserved INFORMATION TO ALL USERS The quality of this reproduction is dependent upon the quality of the copy submitted. In the unlikely event that the author did not send a com plete manuscript and there are missing pages, these will be noted. Also, if material had to be removed, a note will indicate the deletion. uest ProQuest 10609126 Published by ProQuest LLC(2017). Copyright of the Dissertation is held by the Author. All rights reserved. This work is protected against unauthorized copying under Title 17, United States C ode Microform Edition © ProQuest LLC. ProQuest LLC. 789 East Eisenhower Parkway P.O. Box 1346 Ann Arbor, Ml 48106- 1346 ACKNOWLEDGMENTS I would like to acknowledge some of the people that without their kind help and generosity this work would have been difficult. Firstly I would like to thank members of the laboratory group, Fikret for his help, tutoring in yeast genetics, some improved methods and some long coffee breaks explaining the finer details of recombination. Judit for her help in the laboratory and always having a spare lane on a gel and Mark for his assistance with sequencing gels. I would also like to thank the other members of staff at UCL for their help and positive response to favours, Jeremy Hioms’s group, Peter Piper’s group, Laurence Pearl’s group, David Saggerson’s group, Liz Shephard’s group, Jeremy Brockes’s group and Peter Shepherd’s group.
    [Show full text]
  • Functional Effects Detailed Research Plan
    GeCIP Detailed Research Plan Form Background The Genomics England Clinical Interpretation Partnership (GeCIP) brings together researchers, clinicians and trainees from both academia and the NHS to analyse, refine and make new discoveries from the data from the 100,000 Genomes Project. The aims of the partnerships are: 1. To optimise: • clinical data and sample collection • clinical reporting • data validation and interpretation. 2. To improve understanding of the implications of genomic findings and improve the accuracy and reliability of information fed back to patients. To add to knowledge of the genetic basis of disease. 3. To provide a sustainable thriving training environment. The initial wave of GeCIP domains was announced in June 2015 following a first round of applications in January 2015. On the 18th June 2015 we invited the inaugurated GeCIP domains to develop more detailed research plans working closely with Genomics England. These will be used to ensure that the plans are complimentary and add real value across the GeCIP portfolio and address the aims and objectives of the 100,000 Genomes Project. They will be shared with the MRC, Wellcome Trust, NIHR and Cancer Research UK as existing members of the GeCIP Board to give advance warning and manage funding requests to maximise the funds available to each domain. However, formal applications will then be required to be submitted to individual funders. They will allow Genomics England to plan shared core analyses and the required research and computing infrastructure to support the proposed research. They will also form the basis of assessment by the Project’s Access Review Committee, to permit access to data.
    [Show full text]
  • Features China Introduction
    Features China Introduction Tom Blundell (President, the Biochemical Society) This issue of The Biochemist is focused on biochemistry in China. It is timely because it reflects the history of biochemical research collaboration between Chinese and UK scientists, not only by looking back over the last century, but also by reviewing some of the strengths of biochemical research in China in 2011. Downloaded from http://portlandpress.com/biochemist/article-pdf/33/5/4/3914/bio033050004.pdf by guest on 27 September 2021 It has been a busy year for the Biochemical Society, which both in the UK and China. But there were interactions is celebrating its first century. It will do so at the Centenary before Needham became involved. In this issue, Randy Celebration event at the Royal Society in London in Poon draws our attention to one of these, the first paper December, but it has already done so very impressively in from China published in a journal of the Biochemical Shanghai in May with a Joint Sino–UK Protein Symposium. Society. In 1926 Ernest Tso of the Peking Union Medical There we heard about truly momentous contributions College described vitamins in preserved duck eggs, arising from interactions of influential scientists from maintaining they are “as much used on the table as is both China and UK during the last century. Just before cheese in Western countries”. the Symposium, also in May 2011, the Biochemical Journal We should also celebrate Wang Ying-Lai, who did his opened its China office in Beijing with a mini-symposium. PhD in Cambridge between 1938 and 1941.
    [Show full text]
  • Vol 9 No 1 Spring
    A PUBLICATION OF THE AMERICAN SOCIETY FOR MATRIX BIOLOGY SPRING 2010, VOLUME 9, NO. 1 President’s Letter Expanding the Society’s Value to You and Your Role in the Society Since its inception in 2001, the principal function of the ASMB has been to organize the OFFICERS biennial meeting. The value of this meeting to our members cannot be understated. The ASMB meeting has emerged as the matrix-centric President: meeting in North America, and it provides an William Parks (2010) open venue for students, postdocs, fellows, and junior faculty to present their work and to inter- act with established investigators. Speaking for Vice Pres/President Elect myself, I very much look forward to the ASMB Jean Schwarzbauer (2010) meeting, not only because I get to see many Bill Parks friends, but also to hear a lot of incredibly good science. This year’s meeting will be no excep- Past President: tion and promises to be truly outstanding. I applaud Jean Schwarzbauer and the Renato Iozzo (2010) rest of the Program Committee for putting together an exciting meeting loaded with interesting topics and great speakers (please check out the program here). By organizing the meeting, ASMB provides value to you, the membership, but I Secretary/Treasurer think we–the Society–should always be looking to do more; that is, to provide more Joanne Murphy-Ullrich (2011) bang for your dues buck. For this year’s meeting, we have expanded the Travel Awards that will be given to trainees in recognition of outstanding research, and we recently established merit-based Minority Scholarships that will be awarded to eli- Council Members gible students and postdocs.
    [Show full text]
  • Female Fellows of the Royal Society
    Female Fellows of the Royal Society Professor Jan Anderson FRS [1996] Professor Ruth Lynden-Bell FRS [2006] Professor Judith Armitage FRS [2013] Dr Mary Lyon FRS [1973] Professor Frances Ashcroft FMedSci FRS [1999] Professor Georgina Mace CBE FRS [2002] Professor Gillian Bates FMedSci FRS [2007] Professor Trudy Mackay FRS [2006] Professor Jean Beggs CBE FRS [1998] Professor Enid MacRobbie FRS [1991] Dame Jocelyn Bell Burnell DBE FRS [2003] Dr Philippa Marrack FMedSci FRS [1997] Dame Valerie Beral DBE FMedSci FRS [2006] Professor Dusa McDuff FRS [1994] Dr Mariann Bienz FMedSci FRS [2003] Professor Angela McLean FRS [2009] Professor Elizabeth Blackburn AC FRS [1992] Professor Anne Mills FMedSci FRS [2013] Professor Andrea Brand FMedSci FRS [2010] Professor Brenda Milner CC FRS [1979] Professor Eleanor Burbidge FRS [1964] Dr Anne O'Garra FMedSci FRS [2008] Professor Eleanor Campbell FRS [2010] Dame Bridget Ogilvie AC DBE FMedSci FRS [2003] Professor Doreen Cantrell FMedSci FRS [2011] Baroness Onora O'Neill * CBE FBA FMedSci FRS [2007] Professor Lorna Casselton CBE FRS [1999] Dame Linda Partridge DBE FMedSci FRS [1996] Professor Deborah Charlesworth FRS [2005] Dr Barbara Pearse FRS [1988] Professor Jennifer Clack FRS [2009] Professor Fiona Powrie FRS [2011] Professor Nicola Clayton FRS [2010] Professor Susan Rees FRS [2002] Professor Suzanne Cory AC FRS [1992] Professor Daniela Rhodes FRS [2007] Dame Kay Davies DBE FMedSci FRS [2003] Professor Elizabeth Robertson FRS [2003] Professor Caroline Dean OBE FRS [2004] Dame Carol Robinson DBE FMedSci
    [Show full text]
  • Download Our Exhibition Catalogue
    CONTENTS Published to accompany the exhibition at Foreword 04 Two Temple Place, London Dodo, by Gillian Clarke 06 31st january – 27th april 2014 Exhibition curated by Nicholas Thomas Discoveries: Art, Science & Exploration, by Nicholas Thomas 08 and Martin Caiger-Smith, with Lydia Hamlett Published in 2014 by Two Temple Place Kettle’s Yard: 2 Temple Place, Art and Life 18 London wc2r 3bd Museum of Archaeology and Anthropology: Copyright © Two Temple Place Encountering Objects, Encountering People 24 A catalogue record for this publication Museum of Classical Archaeology: is available from the British Library Physical Copies, Metaphysical Discoveries 30 isbn 978-0-9570628-3-2 Museum of Zoology: Designed and produced by NA Creative Discovering Diversity 36 www.na-creative.co.uk The Sedgwick Museum of Earth Sciences: Cover Image: Detail of System According to the Holy Scriptures, Muggletonian print, Discovering the Earth 52 plate 7. Drawn by Isaac Frost. Printed in oil colours by George Baxter Engraved by Clubb & Son. Whipple Museum of the History of Science, The Fitzwilliam Museum: University of Cambridge. A Remarkable Repository 58 Inside Front/Back Cover: Detail of Kitagawa Utamaro (1753-1806), Komei bijin mitate The Polar Museum: Choshingura junimai tsuzuki (The Choshingura drama Exploration into Science 64 parodied by famous beauties: A set of twelve prints). The Fitzwilliam Museum, University of Cambridge. Whipple Museum of the History of Science: Thinking about Discoveries 70 Object List 78 Two Temple Place 84 Acknowledgements 86 Cambridge Museums Map 87 FOREWORD Over eight centuries, the University of Cambridge has been a which were vital to the formation of modern understandings powerhouse of learning, invention, exploration and discovery of nature and natural history.
    [Show full text]
  • SAC 2014 Celebration of Science Book
    Fostering Innovation at MGH Poster Session Abstracts 67th Annual Meeting of the MGH Scientific Advisory Committee Celebration of Science The MGH Research Institute: Meeting the Challenges that Lie Ahead April 2 & 3, 2014 Simches Auditorium 185 Cambridge Street, 3rd Floor Management Management ECOR Administrative Offices | 50 Staniford Street, 10th Floor | Boston, MA 02114 | [email protected] Fostering Mainstay Mainstay Innovation of MGH of MGH at MGH Management Innovation Management Innovation Welcome elcome to the 67th Annual Meeting of the MGH Scientific Advisory Committee (SAC) on April 2nd and 3rd, 2014. Dr. Richard Lifton has graciously agreed to W chair our SAC meeting again this year. As in past years, we will begin our two-day SAC meeting with a Celebration of Science at MGH. Our poster session begins at 11:00 am on Wednesday, April 2, followed by an afternoon Research Symposium from 2:00 pm to 5:00 pm. The outstanding MGH researchers who will be presenting their work in our Symposium this year are the 2014 Howard Goodman Award recipient Filip Swirski, PhD and the 2014 Martin Basic and Clinical Research Prize recipients, Jayaraj Rajagopal, MD, and Stephanie Seminara, MD. We are honored to have as our keynote speaker, Richard O. Hynes, PhD, from MIT. We will close the first day with a Reception for invited guests at the Russell Museum. On Thursday, April 3, Dr. Kingston will open the SAC meeting with an ECOR Report. After this report, Anne Klibanski, MD, Partners Chief Academic Officer, will give a presentation on the Integration of MGH Research to the Partners Enterprise.
    [Show full text]
  • CRISPR and Beyond Perturbations at Scale to Understand Genomes 2-4
    CRISPR and Beyond Perturbations at Scale to Understand Genomes 2-4 September 2019 Wellcome Genome Campus, UK Lectures to be held in the Francis Crick Auditorium Lunch and dinner to be held in the Hall Restaurant Poster sessions to be held in the Conference Centre Spoken presentations - If you are an invited speaker, or your abstract has been selected for a spoken presentation, please give an electronic version of your talk to the AV technician. Poster presentations – If your abstract has been selected for a poster, please display this in the Conference Centre on arrival. Conference programme Monday, 2 September 2019 11:45-12:50 Registration 12:50-13:00 Welcome and introductions Leopold Parts, Wellcome Sanger Institute UK 13.00-14.00 Keynote lecture Allan Bradley Kymab, UK 14:00-15:30 Session 1: Understanding impact of coding variations Chair: Leopold Parts, Wellcome Sanger Institute UK 14:00 New approaches for addressing the effect of genetic variation at scale Douglas Fowler University of Washington, USA 14:30 Tools for systematic proactive functional testing of human missense variants Frederick Roth University of Toronto 15:00 The mutational landscape of a prion-like domain Benedetta Bolognesi Institute for Bioengineering of Catalonia, Spain 15:15 Functional determination of all possible disease-associated variants in a region of CARD11 using saturation genome editing Richard James University of Washington, USA 15:30-16:00 Afternoon tea 16:00-17:30 Session 2: Measuring consequences of non-coding variation Chair: Lea Starita, University
    [Show full text]
  • EMBO Facts & Figures
    excellence in life sciences Reykjavik Helsinki Oslo Stockholm Tallinn EMBO facts & figures & EMBO facts Copenhagen Dublin Amsterdam Berlin Warsaw London Brussels Prague Luxembourg Paris Vienna Bratislava Budapest Bern Ljubljana Zagreb Rome Madrid Ankara Lisbon Athens Jerusalem EMBO facts & figures HIGHLIGHTS CONTACT EMBO & EMBC EMBO Long-Term Fellowships Five Advanced Fellows are selected (page ). Long-Term and Short-Term Fellowships are awarded. The Fellows’ EMBO Young Investigators Meeting is held in Heidelberg in June . EMBO Installation Grants New EMBO Members & EMBO elects new members (page ), selects Young EMBO Women in Science Young Investigators Investigators (page ) and eight Installation Grantees Gerlind Wallon EMBO Scientific Publications (page ). Programme Manager Bernd Pulverer S Maria Leptin Deputy Director Head A EMBO Science Policy Issues report on quotas in academia to assure gender balance. R EMBO Director + + A Conducts workshops on emerging biotechnologies and on H T cognitive genomics. Gives invited talks at US National Academy E IC of Sciences, International Summit on Human Genome Editing, I H 5 D MAN 201 O N Washington, DC.; World Congress on Research Integrity, Rio de A M Janeiro; International Scienti c Advisory Board for the Centre for Eilish Craddock IT 2 015 Mammalian Synthetic Biology, Edinburgh. Personal Assistant to EMBO Fellowships EMBO Scientific Publications EMBO Gold Medal Sarah Teichmann and Ido Amit receive the EMBO Gold the EMBO Director David del Álamo Thomas Lemberger Medal (page ). + Programme Manager Deputy Head EMBO Global Activities India and Singapore sign agreements to become EMBC Associate + + Member States. EMBO Courses & Workshops More than , participants from countries attend 6th scienti c events (page ); participants attend EMBO Laboratory Management Courses (page ); rst online course EMBO Courses & Workshops recorded in collaboration with iBiology.
    [Show full text]
  • Cancer Research UK Manchester Institute SCIENTIFIC REPORT 2019
    SCIENTIFIC REPORT 2019 cruk.org SCIENTIFIC COVER IMAGE Primary cutaneous melanoma (nests of purple cells) invading the dermis. The specimen is REPORT stained with Masson’s trichrome stain. Cyan blue reveals collagen fibre architecture. Image supplied by Amaya Viros (Skin Cancer 2019 and Ageing) MANCHESTER INSTITUTE CONTENTS DIRECTOR’S INTRODUCTION 04 Tim Somervaille 32 RESEARCH SERVICES RESEARCH PUBLICATIONS 64 RESEARCH HIGHLIGHTS 2019 07 Leukaemia Biology Duncan Smith 52 THESES 69 Richard Marais 34 Biological Mass Spectrometry Facility SEMINAR SERIES 2019 70 CANCER RESEARCH UK Molecular Oncology Jen Hughes and Lisa Doar 53 MANCHESTER INSTITUTE OPERATIONS 72 Esther Baena 36 Biological Resources Unit Prostate Oncobiology Wolfgang Breitwieser 55 POSTGRADUATE EDUCATION 80 RESEARCH GROUPS Molecular Biology Core and CANCER RESEARCH UK’S LOCAL 84 Caroline Dive 14 Amaya Virós 38 Computational Biology Support Facility ENGAGEMENT AND DEVELOPMENT Cancer Biomarker Centre Skin Cancer and Ageing Georges Lacaud 40 Garry Ashton 56 ACKNOWLEDGEMENT FOR FUNDING OF 86 Santiago Zelenay 20 THE CANCER RESEARCH UK Stem Cell Biology Histology Cancer Inflammation and Immunity MANCHESTER INSTITUTE Claus Jørgensen 42 Natalia Moncaut 56 Iain Hagan 22 CAREER OPPORTUNITIES AT THE CANCER 87 Systems Oncology Transgenic Production Facility Cell Division RESEARCH UK MANCHESTER INSTITUTE Marek Dynowski 58 Maximiliano Portal 24 Michela Garofalo 44 Scientific Computing CONTACT DETAILS 88 Cell Plasticity & Epigenetics Transcriptional Networks in Lung Cancer Jeff Barry 59 Angeliki Malliri 26 Robert Bristow 46 Flow Cytometry Cell Signalling Translational Oncogenomics Steve Bagley 60 Caroline Springer 28 Patricia Muller 48 Visualisation, Irradiation & Analysis Drug Discovery Tumour Suppressors Robert Metcalf 30 Head and Neck Cancer Biology The Cancer Research UK Manchester Institute is temporarily located at Alderley Park in Cheshire until we return to our original site in The Oglesby Cancer Research Building.
    [Show full text]