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Neural Precursors of Language in Infants at High Risk for Autism Spectrum Disorder
Neural Precursors of Language in Infants at High Risk for Autism Spectrum Disorder The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters Citation Edwards, Laura Ann. 2015. Neural Precursors of Language in Infants at High Risk for Autism Spectrum Disorder. Doctoral dissertation, Harvard Graduate School of Education. Citable link http://nrs.harvard.edu/urn-3:HUL.InstRepos:23519638 Terms of Use This article was downloaded from Harvard University’s DASH repository, and is made available under the terms and conditions applicable to Other Posted Material, as set forth at http:// nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of- use#LAA Neural Precursors of Language in Infants at High Risk for Autism Spectrum Disorder Laura Ann Edwards Tina A. Grotzer Charles A. Nelson Gigi Luk A Thesis Presented to the Faculty of the Graduate School of Education of Harvard University in Partial Fulfillment of the Requirements for the Degree of Doctor of Education 2015 ii © 2015 Laura Ann Edwards All Rights Reserved iii Acknowledgements This dissertation would not have been possible without the contributions of many, throughout my doctoral career. I would first and foremost like to thank the members of my ad hoc committee—Chuck Nelson, Tina Grotzer, and Gigi Luk. Chuck has been my day-to-day mentor since I arrived at Harvard. He has scaffolded my development as a researcher, enabling me to operate autonomously, while always being available to provide support and advice. I am indebted to him for his prompt and thoughtful attention to me, and his mentorship in my past, current, and future academic endeavors. -
Neural Signatures of Autism
Neural signatures of autism Martha D. Kaisera, Caitlin M. Hudaca, Sarah Shultza,b, Su Mei Leea,b, Celeste Cheunga, Allison M. Berkena, Ben Deena, Naomi B. Pitskela, Daniel R. Sugruea, Avery C. Voosa, Celine A. Saulniera, Pamela Ventolaa, Julie M. Wolfa, Ami Klina, Brent C. Vander Wyka, and Kevin A. Pelphreya,b,1 aYale Child Study Center, Yale School of Medicine, New Haven, CT 06520, and bDepartment of Psychology, Yale University, New Haven, CT 06520 Edited by Dale Purves, Duke University Medical Center, Durham, NC, and approved October 13, 2010 (received for review July 19, 2010) Functional magnetic resonance imaging of brain responses to bi- well illustrated by the discovery that point-light displays (i.e., vid- ological motion in children with autism spectrum disorder (ASD), eos created by placing lights on the major joints of a person and unaffected siblings (US) of children with ASD, and typically devel- filming them moving in the dark), although relatively impov- oping (TD) children has revealed three types of neural signatures: (i) erished stimuli, contain sufficient information to identify the kind state activity, related to the state of having ASD that characterizes of motion being produced (e.g., walking, dancing, reaching), as the nature of disruption in brain circuitry; (ii) trait activity, reflecting well as the identity of the agent (8). Visual sensitivity to biological shared areas of dysfunction in US and children with ASD, thereby motion is an evolutionarily well-conserved and ontogenetically providing a promising neuroendophenotype to facilitate efforts to early-emerging mechanism that is fundamental to adaptive social bridge genomic complexity and disorder heterogeneity; and (iii) engagement (9); for example, newly hatched chicks recognize bi- compensatory activity, unique to US, suggesting a neural system– ological motion in point-light displays (10), and 2-d-old human level mechanism by which US might compensate for an increased infants preferentially attend to biological motion in point-light genetic risk for developing ASD. -
Autism Europe
N o 5265 June 2016 English Edition Autism - Europe Our campaign: Respect, Acceptance, Inclusion “On the High Seas”: A film to promote the inclusion of children with autism Jon Spiers, Chief Executive of Autistica, on the report denouncing early death among autistic people Adam Bradford, self-advocate and Queen’s Young Leader 2016: “I hope this recognition inspires other young autistic people to reach their goals” Autism-Europe’s 11th International Congress: Keynote speakers announced Published by Autism-Europe Afgiftekantoor - Bureau de dépôt : Brussels - Ed. responsable : Z. Szilvasy For Diversity Autism-Europe aisbl Rue Montoyer, 39 • B - 1000 Brussels, Belgium Tel.:+32-2-675 75 05 - Fax:+32-2-675 72 70 Against Discrimination E-mail: [email protected] Website: www.autismeurope.org SUMMARY Activities - World Autism Awareness Day campaign 2016 ................... 3 - Autism-Europe’s Annual General Assembly 2016 in Cagliari, Italy .............................................................. 7 News & FeAtures - The “On the High Seas” project ....................................... 8 - Premature mortality among persons with autism. Interview with Jon Spiers, Chief Executive of Autistica .................. 10 - App “Oral Health – SOHDEV” improving oral health Dear friends, for people with autism ................................................... 12 It is with great pleasure that we present this latest edition - Interview with Adam Bradford, self-advocate of our LINK magazine, which offers an overview of Autism- and Queen’s Young Leader 2016 ................................... 13 Europe’s recent activities as well as news from a range - Keynotes speakers announced for Autism-Europe’s th of different stakeholders in the world of autism. In this 11 International Congress ........................................... 14 issue, you will be able to get to know our new member - The “Eight Points” project ............................................ -
Cognitive and Affective Control Deficits in Adults with Autism
City University of New York (CUNY) CUNY Academic Works All Dissertations, Theses, and Capstone Projects Dissertations, Theses, and Capstone Projects 9-2017 Cognitive and Affective Control Deficits in Adults with utismA Spectrum Disorder Melissa-Ann Mackie The Graduate Center, City University of New York How does access to this work benefit ou?y Let us know! More information about this work at: https://academicworks.cuny.edu/gc_etds/2271 Discover additional works at: https://academicworks.cuny.edu This work is made publicly available by the City University of New York (CUNY). Contact: [email protected] COGNITIVE AND AFFECTIVE CONTROL DEFICITS IN ADULTS WITH AUTISM SPECTRUM DISORDER by MELISSA-ANN MACKIE, M.S., M.PHIL. A dissertation submitted to the Graduate Faculty in Psychology in partial fulfillment of the of the requirements of the degree of Doctor of Philosophy, The City University of New York 2017 Ó 2017 MELISSA-ANN MACKIE All Rights Reserved ii Cognitive and Affective Control Deficits in Adults with Autism Spectrum Disorder by Melissa-Ann Mackie, M.S., M.Phil. This manuscript has been read and accepted for the Graduate Faculty in Psychology in satisfaction of the dissertation requirement for the degree of Doctor of Philosophy. ______________________ ____________________________________ Date Jin Fan, Ph.D. Chair of Examining Committee ______________________ ____________________________________ Date Richard Bodnar, Ph.D. Executive Officer Supervisory Committee: Jin Fan, Ph.D. Jeffrey Halperin, Ph.D. Justin Storbeck, Ph.D. Kurt Schulz, Ph.D. A. Ting Wang, Ph.D. THE CITY UNIVERSITY OF NEW YORK iii ABSTRACT Cognitive and Affective Control Deficits in Adults with Autism Spectrum Disorder by Melissa-Ann Mackie, M.S., M.Phil. -
Autism Practice Parameters
American Academy of Child and Adolescent Psychiatry AACAP is pleased to offer Practice Parameters as soon as they are approved by the AACAP Council, but prior to their publication in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP). This article may be revised during the JAACAP copyediting, author query, and proof reading processes. Any final changes in the document will be made at the time of print publication and will be reflected in the final electronic version of the Practice Parameter. AACAP and JAACAP, and its respective employees, are not responsible or liable for the use of any such inaccurate or misleading data, opinion, or information contained in this iteration of this Practice Parameter. PRACTICE PARAMETER FOR THE ASSESSMENT AND TREATMENT OF CHILDREN AND ADOLESCENTS WITH AUTISM SPECTRUM DISORDER ABSTRACT Autism spectrum disorder (ASD) is characterized by patterns of delay and deviance in the development of social, communicative, and cognitive skills which arise in the first years of life. Although frequently associated with intellectual disability, this condition is distinctive in terms of its course, impact, and treatment. ASD has a wide range of syndrome expression and its management presents particular challenges for clinicians. Individuals with an ASD can present for clinical care at any point in development. The multiple developmental and behavioral problems associated with this condition necessitate multidisciplinary care, coordination of services, and advocacy for individuals and their families. Early, sustained intervention and the use of multiple treatment modalities are indicated. Key Words: autism, practice parameters, guidelines, developmental disorders, pervasive developmental disorders. ATTRIBUTION This parameter was developed by Fred Volkmar, M.D., Matthew Siegel, M.D., Marc Woodbury-Smith, M.D., Bryan King, M.D., James McCracken, M.D., Matthew State, M.D., Ph.D. -
May 9-12 Rotterdam Netherlands
2018 ANNUAL MEETING MAY 9-12 ROTTERDAM NETHERLANDS PROGRAM BOOK www.autism-insar.org INSAR 2018 Sponsors We thank the following organizations for their generous support of the INSAR Annual Meeting. Platinum Sponsor Level Gold Sponsor Level Silver Sponsor Level Autism Science Foundation Hilibrand Foundation Nancy Lurie Marks Family Foundation TABLE OF CONTENTS Sponsorship .................................Inside Front Cover TABLE OF CONTENTS Special Interest Groups Schedule .......................... 6 Speaker Ready Room ............................................ 6 De Doelen Floor Plans ........................................ 7-9 Meeting Information Schedule-At-A-Glance .................................... 10-12 In-Conjunction Events .................................... 13-14 Keynote Speakers .............................................. 15 Awardees ..................................................... 16-19 INSAR MISSION Acknowledgments .......................................... 20-21 STATEMENT To promote the highest quality INSAR Summer Institute .................................... 22 research in order to improve the Abstract Author Index ...................................... 134 lives of people affected by autism. General Information .......................................... 208 Exhibitors ....................................................... 210 Strategic Initiatives Setting the Bar: Increase the quality, AM diversity and relevance of research promoted through annual meetings, journal, Keynote Address ............................................... -
Parents Guide to ADHD
Parents Guide to ADHD Copyright 2016. Child Mind Institute Parents Guide to ADHD Children with attention-deficit hyperactivity disorder (ADHD) find it unusually difficult to concentrate on tasks, to pay attention, to sit still and to control impulsive behavior. This guide offers parents the information you need to understand the behaviors associated with the disorder and make effective decisions for your child about diagnosis and treatment. What Is ADHD? Attention-deficit hyperactivity disorder, or ADHD, is a condition that makes it unusually difficult for children to concentrate, to pay attention, to sit still, to follow directions and to control impulsive behavior. While all young children are at times distractible, restless and oblivious to parents’ and teachers’ instructions, kids with ADHD behave this way much more often than other children their age. And their inability to settle down, focus and follow through on tasks in age-appropriate ways makes it very hard for them to do what’s expected of them at school. It can also lead to conflict at home and difficulty getting along with peers. Symptoms of ADHD Symptoms of ADHD are divided into two groups: inattentive behaviors and hyperactive and impulsive behaviors. Inattentive symptoms of ADHD: — Makes careless mistakes — Is easily distracted — Doesn’t seem to be listening when spoken to directly — Has difficulty following instructions — Has trouble organizing — Avoids or dislikes sustained effort — Is forgetful, always losing things Child Mind Institute | Page 2 Parents Guide to ADHD Hyperactive or impulsive symptoms of ADHD: — Fidgeting or squirming, trouble staying in one place or waiting his turn Kids who have inattentive — Excessive running and climbing symptoms may start to — Trouble playing quietly struggle in the middle of — Extreme impatience elementary school, when — Always seems to be “on the go” or “driven by a motor” it becomes increasingly — Excessive talking or interrupting, blurting out answers difficult for them to Some children exhibit only the first group of symptoms, and some exhibit keep up. -
What Is Available for Case Identification in Autism Research in Mainland China?
Research in Autism Spectrum Disorders 7 (2013) 579–590 Contents lists available at SciVerse ScienceDirect Research in Autism Spectrum Disorders Jo urnal homepage: http://ees.elsevier.com/RASD/default.asp What is available for case identification in autism research in mainland China? a,b, b b c b Xiang Sun *, Carrie Allison , Bonnie Auyeung , Fiona E. Matthews , Simon Baron-Cohen , a Carol Brayne a Cambridge Institute of Public Health, Department of Public Health and Primary Care, University of Cambridge, Forvie Site, Robinson Way, CB2 0SR, UK b Autism Research Centre, Department of Psychiatry, University of Cambridge, Douglas House, 18b Trumpington Road, CB2 2AH, UK c MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, CB2 0SR, UK A R T I C L E I N F O A B S T R A C T Little is known about research on Autism Spectrum Conditions (ASC) in mainland China. Article history: Received 22 August 2012 The few available studies in mainland China have shown the screening and diagnostic Received in revised form 26 November 2012 instruments for ASC used in mainland China were different from the West. Literature on Accepted 27 November 2012 screening and diagnostic instruments and criteria were reviewed and current available instruments were identified and evaluated. Eight screening instruments and two Keywords: diagnostic instruments were identified. The Clancy Autism Behaviour Scale (CABS), the Autism Autism Behaviour Checklist (ABC) and the Childhood Autism Rating Scale (CARS) were the Screening instrument most frequently used instruments in mainland China. They were adopted from the West Diagnostic instrument more than two decades ago for detecting individuals with Childhood Autism but not the Mainland China whole autism spectrum. -
Summary of Responses by Question
dialoguebydesign making consultation work Adult Autism Strategy consultation A summary of the submissions received in response to the online consultation Prepared for the Department of Health By Dialogue by Design Ltd January 2010 Adult autism consultation summary report – January 2010 Page 1 dialoguebydesign making consultation work Table of contents 1. Executive Summary ...............................................................................................3 2. Introduction ............................................................................................................5 2.1. Background..................................................................................................5 2.2. How the consultation process was managed...............................................5 2.3. Responses...................................................................................................5 2.4. Participation statistics ..................................................................................5 2.5 Reading this summary and interpreting the results......................................9 3. Consultation overview ..........................................................................................10 3.1. Summary of responses to this chapter.......................................................10 3.2. Standard consultation questions ................................................................11 3.7. Easy-read consultation questions ..............................................................26 4. Social -
Interagency Autism Coordinating Committee
1 INTERAGENCY AUTISM COORDINATING COMMITTEE FULL COMMITTEE MEETING THURSDAY, July 22, 2021 The full Interagency Autism Coordinating Committee (IACC) convened virtually, at 2:00 p.m., Joshua Gordon, M.D., Ph.D., Chair, presiding. PRESENT: JOSHUA GORDON, M.D., Ph.D., Chair, IACC, Director, National Institute of Mental Health, (NIMH) SUSAN DANIELS, Ph.D., Executive Secretary, IACC, Office of Autism Research Coordination (OARC), NIMH COURTNEY FERRELL AKLIN, Ph.D., National Institutes of Health (NIH)(representing Francis Collins, M.D., Ph.D.) MARIA MERCEDES AVILA, Ph.D., M.S.W., M.Ed. University of Vermont SKYE BASS, L.C.S.W., Indian Health Service (IHS) DIANA BIANCHI, M.D., Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) SAMANTHA CRANE, J.D., Autistic Self Advocacy Network 2 PRESENT: (continued) AISHA DICKERSON, Ph.D., Johns Hopkins University TIFFANY FARCHIONE, M.D., U.S. Food and Drug Administration (FDA) MARIA FRYER, M.S., U.S. Department of Justice (DOJ) DAYANA GARCIA, M.Ed., Administration for Children and Families (ACF) DENA GASSNER, M.S.W., Adelphi University MORÉNIKE GIWA ONAIWU, M.A., Rice University ALYCIA HALLADAY, Ph.D., Autism Science Foundation CRAIG JOHNSON, B.A. Champions Foundation JENNIFER JOHNSON, Ed.D., Administration for Community Living (ACL) CINDY LAWLER, Ph.D., National Institute of Environmental Health Sciences (NIEHS) (representing Rick Woychik, Ph.D.) ALISON MARVIN, Ph.D., Social Security Administration (SSA) LINDSEY NEBEKER,B.A., Freelance Presenter/Trainer SCOTT PATTERSON, Ph.D., U.S. Department of Veterans Affairs (VA)(representing Matthew Miller, Ph.D., M.P.H.) VALERIE PARADIZ, Ph.D., Autism Speaks 3 PRESENT (continued) GEORGINA PEACOCK, M.D., M.P.H., F.A.A.P., Centers for Disease Control and Prevention (CDC) JENNY MAI PHAN, Ph.D., University of Wisconsin-Madison JOSEPH PIVEN, M.D., University of North Carolina-Chapel Hill JALYNN PRINCE, B.F.A., Madison House Autism Foundation LAUREN RAMOS, M.P.H., Health Resources and Services Administration (HRSA) SCOTT MICHAEL ROBERTSON, Ph.D., U.S. -
Early Identification of Autism by the Checklist
JOURNAL OF THE ROYAL SOCIETY OF MEDICINE Volume 93 October 2000 Early identi®cation of autism by the CHecklist for Autism in Toddlers CHAT) Simon Baron-Cohen PhD Sally Wheelwright MSc Antony Cox FRCPsych1 Gillian Baird FRCPCH1 Tony Charman PhD2 John Swettenham PhD3 Auriol Drew MA1 Peter Doehring PhD4 J R Soc Med 2000;93:521±525 The CHecklist for Autism in Toddlers CHAT) is a syndrome are present, together with a history of language screening instrument that identi®es children aged 18 delay de®ned as not using single words by two years old or months who are at risk for autism. This article explains phrase speech by three years old). how the CHAT was developed and how it should be used. First we offer a brief introduction to autism. EARLY DETECTION Until recently, autism was seldom detected before the age WHAT IS AUTISM? of three years. This is not surprising since it is a relatively Autism, ®rst described by Kanner in 19431, is one of a uncommon condition and can have subtle manifestations. family of `pervasive developmental disorders2. The most No specialized screening tool exists and most primary severe of the childhood psychiatric conditions, it is healthcare professionals have little training in the detection characterized by a triad of impairmentsÐin socialization, of autism in toddlers. However, the earlier a diagnosis can communication and ¯exible behaviour. The exact cause is be made, the sooner family stress can be reduced; unclear but family and twin studies suggest a genetic basis3±5; moreover, intervention can improve outcome12.In molecular genetic studies are underway6. -
Committee Business
IACC Committee Business IACC Full Committee Meeting April 19, 2018 Susan A. Daniels, Ph.D. Director, Office of Autism Research Coordination Executive Secretary, IACC National Institute of Mental Health Thanks to OARC Staff Susan Daniels, Ph.D. Director Oni Celestin, Ph.D. Julianna Rava, M.P.H. Science Policy Analyst Science Policy Analyst Rebecca Martin, M.P.H Matthew Vilnit, B.S. Public Health Analyst Operations Coordinator Angelice Mitrakas, B.A. Jeff Wiegand, B.S. Management Analyst Web Development Manager Karen Mowrer, Ph.D. Science Policy Analyst April is National Autism Awareness Month NIMH Special Event for Autism Awareness Month The Story Behind Julia, Sesame Street’s Muppet with Autism April 9, 2018 • Panel presentation featuring speakers from Sesame Workshop, the nonprofit educational organization behind Sesame Street • Meet-and-greet with a costumed Julia character Archived video available: https://iacc.hhs.gov/meetings/autism- events/2018/april9/sesame- street.shtml#video Autism Awareness Month News • 2018 Presidential Proclamation: President Donald J. Trump Proclaims April 2, 2018, World Autism Awareness Day • 2018 UN Secretary-General Message: António Guterres' Message on World Autism Awareness Day Autism Awareness Month Events • Autism Awareness Interagency Roundtable Indian Health Service April 2, 2018; Bethesda, MD • Empowering Women and Girls with Autism United Nations April 5, 2018; New York, NY Event page: https://www.un.org/en/events/autismday/ Archived video available: https://www.youtube.com/watch?v=Tyhm7p8Gr2A