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1 Table S1. Outlier Loci Detected by Deepgenomescan Using Table S1. Outlier loci detected by DeepGenomeScan using geographic coordinates. Loci highlighted in red are detected by DeepGenomeScan but are not listed in Yang et al. (2012; Supplementary Table 4). RsID is annotated according to the dbSNP database released on 21st April, 2020. CHR BP (Grch37) BP (Grch38) rsID p.value Genes 1 1:4208918 1:4148858 rs9426495 3.8582E-104 1 1:175738168 1:175769032 rs6425357 2.0088E-105 2 2:20310668 2:20110907 rs11679737 1.2002E-111 LAPTM4A-DT 2 2:40289267 2:40062127 rs759361 5.5658E-104 SLC8A1-AS1 2 2:82495127 2:82268003 rs6726401 3.9451E-103 2 2:96660300 2:95994552 rs2579520 1.8176E-127 2 2:96672001 2:96006253 rs1917890 3.7698E-104 2 2:134333012 2:133575441 rs17816830 9.702E-105 NCKAP5 2 2:134350570 2:133592999 rs6715224 5.8745E-111 NCKAP5 2 2:134912243 2:134154672 rs2139309 1.7418E-191 MGAT5 2 2:134917005 2:134159434 rs11692586 9.2121E-151 MGAT5 2 2:134972732 2:134215161 rs11679218 0 MGAT5 2 2:134979966 2:134222395 rs1965183 5.3171E-107 MGAT5 2 2:135260071 2:134502500 rs503562 2.057E-153 TMEM163 2 2:135280039 2:134522468 rs579670 3.1477E-118 TMEM163 2 2:135285279 2:134527708 rs512375 0 TMEM163 2 2:135290221 2:134532650 rs655472 0 TMEM163 2 2:135290453 2:134532882 rs666614 0 TMEM163 2 2:135340840 2:134583270 rs842361 5.6717E-237 TMEM163 2 2:135393110 2:134635540 rs11684785 2.2164E-276 TMEM163 2 2:135430709 2:134673139 rs6745983 0 TMEM163 2 2:135469769 2:134712199 rs6747870 9.6117E-114 TMEM163 2 2:135483381 2:134725811 rs3739034 5.0357E-154 2 2:135483534 2:134725964 rs3739036 3.7269E-156 2 2:135539967 2:134782397 rs6430538 0 2 2:135602601 2:134845031 rs6430545 0 ACMSD 2 2:135606879 2:134849309 rs1530557 0 ACMSD 2 2:135612422 2:134854852 rs6430547 0 ACMSD 2 2:135618982 2:134861412 rs6706537 0 ACMSD 2 2:135623517 2:134865947 rs7593370 0 ACMSD 2 2:135629927 2:134872357 rs12469941 0 ACMSD, CCNT2-AS1 2 2:135637338 2:134879768 rs2166480 0 ACMSD, CCNT2-AS1 2 2:135657471 2:134899901 rs10176573 0 ACMSD, CCNT2-AS1 2 2:135693537 2:134935967 rs6743206 2.0048E-214 CCNT2 2 2:135694379 2:134936809 rs1374289 0 CCNT2 2 2:135694848 2:134937278 rs4953938 0 CCNT2 2 2:135737908 2:134980338 rs4954209 4.6215E-270 MAP3K19 2 2:135762344 2:135004774 rs16831243 2.8757E-253 MAP3K19 1 2 2:135762656 2:135005086 rs10197646 3.3948E-218 MAP3K19 2 2:135775130 2:135017560 rs7581382 0 MAP3K19 2 2:135803425 2:135045855 rs4954218 0 MAP3K19 2 2:135907088 2:135149518 rs6730157 0 RAB3GAP1 2 2:136388473 2:135630903 rs10187054 0 R3HDM1 2 2:136419961 2:135662391 rs1446584 0 R3HDM1 2 2:136420690 2:135663120 rs4954280 0 R3HDM1 2 2:136462661 2:135705091 rs2117511 3.0786E-143 R3HDM1 2 2:136499166 2:135741596 rs1438307 0 UBXN4, LOC107985946 2 2:136506927 2:135749357 rs6430585 0 UBXN4 2 2:136545844 2:135788274 rs1042712 0 LCT 2 2:136555525 2:135797955 rs2015532 0 LCT 2 2:136556182 2:135798612 rs3769013 2.3001E-307 LCT 2 2:136556480 2:135798910 rs3769012 0 LCT 2 2:136556805 2:135799235 rs872151 6.4599E-149 LCT 2 2:136557319 2:135799749 rs2322660 0 LCT 2 2:136561557 2:135803987 rs2304371 0 LCT 2 2:136571982 2:135814412 rs4954445 3.6282E-117 LCT 2 2:136614255 2:135856685 rs309180 0 MCM6 2 2:136628121 2:135870551 rs4988163 4.0179E-286 MCM6 2 2:136637350 2:135879780 rs16832138 1.5766E-116 2 2:136641593 2:135884023 rs7581814 0 2 2:136694905 2:135937335 rs7573555 0 DARS1 2 2:136702601 2:135945031 rs6743537 0 DARS1 2 2:136719173 2:135961603 rs6430594 0 DARS1 2 2:136765951 2:136008381 rs309137 0 2 2:136770509 2:136012939 rs12471781 0 2 2:136786651 2:136029081 rs12475139 0 2 2:136806774 2:136049204 rs7371606 0 2 2:136808949 2:136051379 rs11693502 0 2 2:136910273 2:136152703 rs6715785 0 2 2:136921703 2:136164133 rs10180515 2.2455E-281 2 2:136956733 2:136199163 rs7578292 3.7209E-216 2 2:136963794 2:136206224 rs12691876 1.3461E-265 2 2:136973781 2:136216211 rs1519528 9.1417E-244 LOC107985947 2 2:137037386 2:136279816 rs4954599 1.0298E-196 2 2:137057148 2:136299578 rs13008975 1.6878E-135 2 2:137058248 2:136300678 rs4296479 4.9792E-133 2 2:137058433 2:136300863 rs4599171 4.0031E-214 2 2:137197151 2:136439581 rs7561441 5.3311E-173 2 2:137300091 2:136542521 rs10205768 5.1224E-276 2 2:137341944 2:136584374 rs12691894 1.1911E-163 2 2 2:137433213 2:136675643 rs11681380 1.5164E-192 2 2:137475070 2:136717500 rs7582192 5.155E-212 2 2:137496806 2:136739236 rs10199153 8.9959E-130 2 2:137512698 2:136755128 rs7564005 2.1506E-128 2 2:137514418 2:136756848 rs1427591 1.253E-146 2 2:137610518 2:136852948 rs778207 2.4208E-196 THSD7B 2 2:137612229 2:136854659 rs778202 2.0497E-109 THSD7B 2 2:137614786 2:136857216 rs1429978 3.9634E-206 THSD7B 2 2:160867553 2:160011042 rs2667012 1.0935E-118 PLA2R1 2 2:160891688 2:160035177 rs17830904 6.4076E-116 PLA2R1 2 2:160906931 2:160050420 rs10929965 7.3545E-120 PLA2R1 2 2:160912652 2:160056141 rs925410 2.3118E-126 PLA2R1, LOC105373717 2 2:160914156 2:160057645 rs17831251 3.7725E-121 PLA2R1, LOC105373717 2 2:160914540 2:160058029 rs6707458 5.846E-116 PLA2R1, LOC105373717 2 2:160915106 2:160058595 rs16844715 4.6953E-126 PLA2R1, LOC105373717 2 2:166924472 2:166067962 rs1461197 2.2877E-104 SCN1A 2 2:174486590 2:173621862 rs6722856 2.9251E-127 LOC107985961 2 2:177977545 2:177112817 rs2588865 3.7631E-139 LOC105373760 2 2:177991618 2:177126890 rs2706137 3.1043E-172 LOC105373760 3 3:45846769 3:45805277 rs17763742 1.8336E-162 LOC107986082 3 3:81427818 3:81378667 rs275360 3.1048E-120 3 3:127416142 3:127697299 rs782440 1.8735E-121 MGLL 3 3:127417202 3:127698359 rs782437 9.6119E-114 MGLL 3 3:127426929 3:127708086 rs1071912 2.7892E-104 MGLL 3 3:178429939 3:178712151 rs9290663 4.5367E-112 KCNMB2, KCNMB2-AS1 3 3:178995657 3:179277869 rs9813206 3.7674E-125 4 4:14093170 4:14091546 rs7673306 4.0281E-109 4 4:38768533 4:38766912 rs10470854 4.5861E-114 4 4:38776303 4:38774682 rs11466652 5.0508E-141 TLR10 4 4:38776491 4:38774870 rs11096957 8.3115E-109 TLR10 4 4:38783964 4:38782343 rs4321646 1.4399E-155 TLR10 4 4:38787216 4:38785595 rs12233670 4.7111E-144 4 4:38894380 4:38892759 rs6835514 4.1487E-200 FAM114A1 4 4:38908038 4:38906417 rs4832790 7.1817E-108 FAM114A1 4 4:84909466 4:83988313 rs4693665 5.537E-127 LOC101928978 4 4:100260274 4:99339117 rs1693476 2.4983E-155 ADH1C 4 4:100262041 4:99340884 rs1789903 2.3041E-165 ADH1C 4 4:100263778 4:99342621 rs1789911 5.5025E-158 ADH1C 4 4:100285148 4:99363991 rs1154435 9.4022E-145 4 4:103243101 4:102321944 rs17278473 2.2816E-103 SLC39A8 4 4:112051824 4:111130668 rs294942 1.1955E-129 5 5:36368967 5:36368865 rs4602650 3.9055E-113 3 5 5:110472967 5:111137269 rs464275 2.278E-141 6 6:27987776 6:28019998 rs149976 5.1992E-136 6 6:28100640 6:28132862 rs1225710 5.0364E-157 ZSCAN16-AS1 6 6:28113373 6:28145595 rs1225715 1.3359E-139 ZKSCAN8 6 6:28391465 6:28423688 rs2859365 3.2334E-133 LOC105374997 6 6:28415572 6:28447795 rs13215804 1.458E-224 6 6:28417222 6:28449445 rs6903535 1.1153E-191 6 6:28542520 6:28574743 rs370520 7.3625E-166 ZBED9 6 6:28665362 6:28697585 rs7382146 5.3108E-300 LOC101929006, 6 6:29256420 6:29288643 rs1884123 2.2056E-105 LOC105375005 6 6:30103360 6:30135583 rs1541269 1.1572E-107 TRIM40 6 6:30152467 6:30184690 rs11158 4.2464E-119 TRIM26 6 6:30328192 6:30360415 rs3130351 1.0679E-104 6 6:30363351 6:30395574 rs3094034 2.9109E-102 6 6:30739972 6:30772195 rs3132605 2.572E-102 HCG20 6 6:31025713 6:31057936 rs2517524 7.1036E-144 HCG22 6 6:31030122 6:31062345 rs2517510 2.4694E-197 6 6:31030283 6:31062506 rs2523841 2.188E-123 6 6:31030425 6:31062648 rs2523840 4.7541E-127 6 6:31042070 6:31074293 rs2523883 4.2821E-181 6 6:31042306 6:31074529 rs2517489 2.4633E-192 6 6:31042608 6:31074831 rs2523881 6.9967E-188 6 6:31042769 6:31074992 rs2523880 2.4424E-165 6 6:31051388 6:31083611 rs2535318 1.4176E-189 6 6:31052098 6:31084321 rs2517471 9.6266E-197 6 6:31053867 6:31086090 rs2535306 5.342E-202 6 6:31172655 6:31204878 rs2894180 8.1758E-109 6 6:31255500 6:31287723 rs2524051 2.4487E-163 6 6:31265554 6:31297777 rs2524115 3.9166E-141 LINC02571, LOC112267902 6 6:31277686 6:31309909 rs1634788 6.1552E-102 LOC112267902 6 6:31333939 6:31366162 rs7761068 1.6372E-158 6 6:31336649 6:31368872 rs2523533 5.5187E-127 6 6:31379931 6:31412154 rs1063635 2.1436E-251 MICA 6 6:31777946 6:31810169 rs2075800 4.1936E-126 HSPA1L 6 6:31856070 6:31888293 rs486416 0 EHMT2 6 6:31883957 6:31916180 rs644045 7.5006E-221 C2 6 6:31919578 6:31951801 rs2072633 0 CFB, NELFE 6 6:32179896 6:32212119 rs2071286 2.5495E-111 NOTCH4 6 6:32200147 6:32232370 rs3134926 2.8449E-106 6 6:32216850 6:32249073 rs3115576 4.511E-241 6 6:32217367 6:32249590 rs3130311 2.0337E-237 6 6:32288190 6:32320413 rs574710 1.366E-230 TSBP1, TSBP1-AS1 4 6 6:32305690 6:32337913 rs926591 1.3828E-249 TSBP1, TSBP1-AS2 6 6:32313097 6:32345320 rs4959093 1.0302E-241 TSBP1, TSBP1-AS3 6 6:32389512 6:32421735 rs9268560 5.1383E-297 6 6:32408527 6:32440750 rs9268645 1.172E-227 HLA-DRA 6 6:32429758 6:32461981 rs9268858 2.0363E-156 6 6:32431147 6:32463370 rs9268877 0 6 6:32626272 6:32658495 rs9273363 5.5519E-129 HLA-DQB1-AS1 6 6:32635296 6:32667519 rs6908943 3.3296E-144 HLA-DQB1 6 6:32689529 6:32721752 rs9461799 2.3913E-199 6 6:32690001 6:32722224 rs9469240 2.4622E-170 6 6:32711782 6:32744005 rs2227127 9.9757E-175 HLA-DQA2 6 6:32712384 6:32744607 rs9276432 1.1768E-129 HLA-DQA2 6 6:32736144 6:32768367 rs9296044 6.0615E-120 6 6:32965942 6:32998165 rs176248 3.5831E-139 6 6:79190083 6:78480366 rs10943541 5.1113E-117 6 6:79212957 6:78503240 rs4632856 4.0872E-115 6 6:79232161 6:78522444 rs4706060 5.8085E-109 6 6:152942821 6:152621686 rs1744380 4.3781E-102 SYNE1 6 6:152950053 6:152628918 rs2057399 2.4192E-115 SYNE1 6 6:152966084 6:152644949 rs2758813 1.212E-121 6 6:153007917 6:152686782 rs2800629 8.0585E-128 LOC105378061
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