Table S1. Outlier loci detected by DeepGenomeScan using geographic coordinates. Loci highlighted in red are detected by DeepGenomeScan but are not listed in Yang et al. (2012; Supplementary Table 4). RsID is annotated according to the dbSNP database released on 21st April, 2020. CHR BP (Grch37) BP (Grch38) rsID p.value Genes 1 1:4208918 1:4148858 rs9426495 3.8582E-104 1 1:175738168 1:175769032 rs6425357 2.0088E-105 2 2:20310668 2:20110907 rs11679737 1.2002E-111 LAPTM4A-DT 2 2:40289267 2:40062127 rs759361 5.5658E-104 SLC8A1-AS1 2 2:82495127 2:82268003 rs6726401 3.9451E-103 2 2:96660300 2:95994552 rs2579520 1.8176E-127 2 2:96672001 2:96006253 rs1917890 3.7698E-104 2 2:134333012 2:133575441 rs17816830 9.702E-105 NCKAP5 2 2:134350570 2:133592999 rs6715224 5.8745E-111 NCKAP5 2 2:134912243 2:134154672 rs2139309 1.7418E-191 MGAT5 2 2:134917005 2:134159434 rs11692586 9.2121E-151 MGAT5 2 2:134972732 2:134215161 rs11679218 0 MGAT5 2 2:134979966 2:134222395 rs1965183 5.3171E-107 MGAT5 2 2:135260071 2:134502500 rs503562 2.057E-153 TMEM163 2 2:135280039 2:134522468 rs579670 3.1477E-118 TMEM163 2 2:135285279 2:134527708 rs512375 0 TMEM163 2 2:135290221 2:134532650 rs655472 0 TMEM163 2 2:135290453 2:134532882 rs666614 0 TMEM163 2 2:135340840 2:134583270 rs842361 5.6717E-237 TMEM163 2 2:135393110 2:134635540 rs11684785 2.2164E-276 TMEM163 2 2:135430709 2:134673139 rs6745983 0 TMEM163 2 2:135469769 2:134712199 rs6747870 9.6117E-114 TMEM163 2 2:135483381 2:134725811 rs3739034 5.0357E-154 2 2:135483534 2:134725964 rs3739036 3.7269E-156 2 2:135539967 2:134782397 rs6430538 0 2 2:135602601 2:134845031 rs6430545 0 ACMSD 2 2:135606879 2:134849309 rs1530557 0 ACMSD 2 2:135612422 2:134854852 rs6430547 0 ACMSD 2 2:135618982 2:134861412 rs6706537 0 ACMSD 2 2:135623517 2:134865947 rs7593370 0 ACMSD 2 2:135629927 2:134872357 rs12469941 0 ACMSD, CCNT2-AS1 2 2:135637338 2:134879768 rs2166480 0 ACMSD, CCNT2-AS1 2 2:135657471 2:134899901 rs10176573 0 ACMSD, CCNT2-AS1 2 2:135693537 2:134935967 rs6743206 2.0048E-214 CCNT2 2 2:135694379 2:134936809 rs1374289 0 CCNT2 2 2:135694848 2:134937278 rs4953938 0 CCNT2 2 2:135737908 2:134980338 rs4954209 4.6215E-270 MAP3K19 2 2:135762344 2:135004774 rs16831243 2.8757E-253 MAP3K19 1 2 2:135762656 2:135005086 rs10197646 3.3948E-218 MAP3K19 2 2:135775130 2:135017560 rs7581382 0 MAP3K19 2 2:135803425 2:135045855 rs4954218 0 MAP3K19 2 2:135907088 2:135149518 rs6730157 0 RAB3GAP1 2 2:136388473 2:135630903 rs10187054 0 R3HDM1 2 2:136419961 2:135662391 rs1446584 0 R3HDM1 2 2:136420690 2:135663120 rs4954280 0 R3HDM1 2 2:136462661 2:135705091 rs2117511 3.0786E-143 R3HDM1 2 2:136499166 2:135741596 rs1438307 0 UBXN4, LOC107985946 2 2:136506927 2:135749357 rs6430585 0 UBXN4 2 2:136545844 2:135788274 rs1042712 0 LCT 2 2:136555525 2:135797955 rs2015532 0 LCT 2 2:136556182 2:135798612 rs3769013 2.3001E-307 LCT 2 2:136556480 2:135798910 rs3769012 0 LCT 2 2:136556805 2:135799235 rs872151 6.4599E-149 LCT 2 2:136557319 2:135799749 rs2322660 0 LCT 2 2:136561557 2:135803987 rs2304371 0 LCT 2 2:136571982 2:135814412 rs4954445 3.6282E-117 LCT 2 2:136614255 2:135856685 rs309180 0 MCM6 2 2:136628121 2:135870551 rs4988163 4.0179E-286 MCM6 2 2:136637350 2:135879780 rs16832138 1.5766E-116 2 2:136641593 2:135884023 rs7581814 0 2 2:136694905 2:135937335 rs7573555 0 DARS1 2 2:136702601 2:135945031 rs6743537 0 DARS1 2 2:136719173 2:135961603 rs6430594 0 DARS1 2 2:136765951 2:136008381 rs309137 0 2 2:136770509 2:136012939 rs12471781 0 2 2:136786651 2:136029081 rs12475139 0 2 2:136806774 2:136049204 rs7371606 0 2 2:136808949 2:136051379 rs11693502 0 2 2:136910273 2:136152703 rs6715785 0 2 2:136921703 2:136164133 rs10180515 2.2455E-281 2 2:136956733 2:136199163 rs7578292 3.7209E-216 2 2:136963794 2:136206224 rs12691876 1.3461E-265 2 2:136973781 2:136216211 rs1519528 9.1417E-244 LOC107985947 2 2:137037386 2:136279816 rs4954599 1.0298E-196 2 2:137057148 2:136299578 rs13008975 1.6878E-135 2 2:137058248 2:136300678 rs4296479 4.9792E-133 2 2:137058433 2:136300863 rs4599171 4.0031E-214 2 2:137197151 2:136439581 rs7561441 5.3311E-173 2 2:137300091 2:136542521 rs10205768 5.1224E-276 2 2:137341944 2:136584374 rs12691894 1.1911E-163 2 2 2:137433213 2:136675643 rs11681380 1.5164E-192 2 2:137475070 2:136717500 rs7582192 5.155E-212 2 2:137496806 2:136739236 rs10199153 8.9959E-130 2 2:137512698 2:136755128 rs7564005 2.1506E-128 2 2:137514418 2:136756848 rs1427591 1.253E-146 2 2:137610518 2:136852948 rs778207 2.4208E-196 THSD7B 2 2:137612229 2:136854659 rs778202 2.0497E-109 THSD7B 2 2:137614786 2:136857216 rs1429978 3.9634E-206 THSD7B 2 2:160867553 2:160011042 rs2667012 1.0935E-118 PLA2R1 2 2:160891688 2:160035177 rs17830904 6.4076E-116 PLA2R1 2 2:160906931 2:160050420 rs10929965 7.3545E-120 PLA2R1 2 2:160912652 2:160056141 rs925410 2.3118E-126 PLA2R1, LOC105373717 2 2:160914156 2:160057645 rs17831251 3.7725E-121 PLA2R1, LOC105373717 2 2:160914540 2:160058029 rs6707458 5.846E-116 PLA2R1, LOC105373717 2 2:160915106 2:160058595 rs16844715 4.6953E-126 PLA2R1, LOC105373717 2 2:166924472 2:166067962 rs1461197 2.2877E-104 SCN1A 2 2:174486590 2:173621862 rs6722856 2.9251E-127 LOC107985961 2 2:177977545 2:177112817 rs2588865 3.7631E-139 LOC105373760 2 2:177991618 2:177126890 rs2706137 3.1043E-172 LOC105373760 3 3:45846769 3:45805277 rs17763742 1.8336E-162 LOC107986082 3 3:81427818 3:81378667 rs275360 3.1048E-120 3 3:127416142 3:127697299 rs782440 1.8735E-121 MGLL 3 3:127417202 3:127698359 rs782437 9.6119E-114 MGLL 3 3:127426929 3:127708086 rs1071912 2.7892E-104 MGLL 3 3:178429939 3:178712151 rs9290663 4.5367E-112 KCNMB2, KCNMB2-AS1 3 3:178995657 3:179277869 rs9813206 3.7674E-125 4 4:14093170 4:14091546 rs7673306 4.0281E-109 4 4:38768533 4:38766912 rs10470854 4.5861E-114 4 4:38776303 4:38774682 rs11466652 5.0508E-141 TLR10 4 4:38776491 4:38774870 rs11096957 8.3115E-109 TLR10 4 4:38783964 4:38782343 rs4321646 1.4399E-155 TLR10 4 4:38787216 4:38785595 rs12233670 4.7111E-144 4 4:38894380 4:38892759 rs6835514 4.1487E-200 FAM114A1 4 4:38908038 4:38906417 rs4832790 7.1817E-108 FAM114A1 4 4:84909466 4:83988313 rs4693665 5.537E-127 LOC101928978 4 4:100260274 4:99339117 rs1693476 2.4983E-155 ADH1C 4 4:100262041 4:99340884 rs1789903 2.3041E-165 ADH1C 4 4:100263778 4:99342621 rs1789911 5.5025E-158 ADH1C 4 4:100285148 4:99363991 rs1154435 9.4022E-145 4 4:103243101 4:102321944 rs17278473 2.2816E-103 SLC39A8 4 4:112051824 4:111130668 rs294942 1.1955E-129 5 5:36368967 5:36368865 rs4602650 3.9055E-113 3 5 5:110472967 5:111137269 rs464275 2.278E-141 6 6:27987776 6:28019998 rs149976 5.1992E-136 6 6:28100640 6:28132862 rs1225710 5.0364E-157 ZSCAN16-AS1 6 6:28113373 6:28145595 rs1225715 1.3359E-139 ZKSCAN8 6 6:28391465 6:28423688 rs2859365 3.2334E-133 LOC105374997 6 6:28415572 6:28447795 rs13215804 1.458E-224 6 6:28417222 6:28449445 rs6903535 1.1153E-191 6 6:28542520 6:28574743 rs370520 7.3625E-166 ZBED9 6 6:28665362 6:28697585 rs7382146 5.3108E-300 LOC101929006, 6 6:29256420 6:29288643 rs1884123 2.2056E-105 LOC105375005 6 6:30103360 6:30135583 rs1541269 1.1572E-107 TRIM40 6 6:30152467 6:30184690 rs11158 4.2464E-119 TRIM26 6 6:30328192 6:30360415 rs3130351 1.0679E-104 6 6:30363351 6:30395574 rs3094034 2.9109E-102 6 6:30739972 6:30772195 rs3132605 2.572E-102 HCG20 6 6:31025713 6:31057936 rs2517524 7.1036E-144 HCG22 6 6:31030122 6:31062345 rs2517510 2.4694E-197 6 6:31030283 6:31062506 rs2523841 2.188E-123 6 6:31030425 6:31062648 rs2523840 4.7541E-127 6 6:31042070 6:31074293 rs2523883 4.2821E-181 6 6:31042306 6:31074529 rs2517489 2.4633E-192 6 6:31042608 6:31074831 rs2523881 6.9967E-188 6 6:31042769 6:31074992 rs2523880 2.4424E-165 6 6:31051388 6:31083611 rs2535318 1.4176E-189 6 6:31052098 6:31084321 rs2517471 9.6266E-197 6 6:31053867 6:31086090 rs2535306 5.342E-202 6 6:31172655 6:31204878 rs2894180 8.1758E-109 6 6:31255500 6:31287723 rs2524051 2.4487E-163 6 6:31265554 6:31297777 rs2524115 3.9166E-141 LINC02571, LOC112267902 6 6:31277686 6:31309909 rs1634788 6.1552E-102 LOC112267902 6 6:31333939 6:31366162 rs7761068 1.6372E-158 6 6:31336649 6:31368872 rs2523533 5.5187E-127 6 6:31379931 6:31412154 rs1063635 2.1436E-251 MICA 6 6:31777946 6:31810169 rs2075800 4.1936E-126 HSPA1L 6 6:31856070 6:31888293 rs486416 0 EHMT2 6 6:31883957 6:31916180 rs644045 7.5006E-221 C2 6 6:31919578 6:31951801 rs2072633 0 CFB, NELFE 6 6:32179896 6:32212119 rs2071286 2.5495E-111 NOTCH4 6 6:32200147 6:32232370 rs3134926 2.8449E-106 6 6:32216850 6:32249073 rs3115576 4.511E-241 6 6:32217367 6:32249590 rs3130311 2.0337E-237 6 6:32288190 6:32320413 rs574710 1.366E-230 TSBP1, TSBP1-AS1 4 6 6:32305690 6:32337913 rs926591 1.3828E-249 TSBP1, TSBP1-AS2 6 6:32313097 6:32345320 rs4959093 1.0302E-241 TSBP1, TSBP1-AS3 6 6:32389512 6:32421735 rs9268560 5.1383E-297 6 6:32408527 6:32440750 rs9268645 1.172E-227 HLA-DRA 6 6:32429758 6:32461981 rs9268858 2.0363E-156 6 6:32431147 6:32463370 rs9268877 0 6 6:32626272 6:32658495 rs9273363 5.5519E-129 HLA-DQB1-AS1 6 6:32635296 6:32667519 rs6908943 3.3296E-144 HLA-DQB1 6 6:32689529 6:32721752 rs9461799 2.3913E-199 6 6:32690001 6:32722224 rs9469240 2.4622E-170 6 6:32711782 6:32744005 rs2227127 9.9757E-175 HLA-DQA2 6 6:32712384 6:32744607 rs9276432 1.1768E-129 HLA-DQA2 6 6:32736144 6:32768367 rs9296044 6.0615E-120 6 6:32965942 6:32998165 rs176248 3.5831E-139 6 6:79190083 6:78480366 rs10943541 5.1113E-117 6 6:79212957 6:78503240 rs4632856 4.0872E-115 6 6:79232161 6:78522444 rs4706060 5.8085E-109 6 6:152942821 6:152621686 rs1744380 4.3781E-102 SYNE1 6 6:152950053 6:152628918 rs2057399 2.4192E-115 SYNE1 6 6:152966084 6:152644949 rs2758813 1.212E-121 6 6:153007917 6:152686782 rs2800629 8.0585E-128 LOC105378061