“The End of Science”: Can We Overcome Cognitive Limitations?
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From Developmental Constraint to Evolvability
From Developmental Constraint to Evolvability How Concepts Figure in Explanation and Disciplinary Identity Ingo Brigandt Department of Philosophy, University of Alberta 2-40 Assiniboia Hall, Edmonton, AB T6G2E7, Canada [email protected] Abstract The concept of developmental constraint was at the heart of develop- mental approaches to evolution of the 1980s. While this idea was widely used to criticize neo-Darwinian evolutionary theory, critique does not yield an alternative framework that offers evolutionary explanations. In current Evo-devo the concept of constraint is of minor importance, whereas notions as evolvability are at the center of attention. The latter clearly defines an explanatory agenda for evolution- ary research, so that one could view the historical shift from ‘developmental con- straint’ towards ‘evolvability’ as the move from a concept that is a mere tool of criticism to a concept that establishes a positive explanatory project. However, by taking a look at how the concept of constraint was employed in the 1980s, I argue that developmental constraint was not just seen as restricting possibilities (‘con- straining’), but also as facilitating morphological change in several ways. Ac- counting for macroevolutionary transformation and the origin of novel form was an aim of these developmental approaches to evolution. Thus, the concept of de- velopmental constraint was part of a positive explanatory agenda long before the advent of Evo-devo as a genuine scientific discipline. In the 1980s, despite the lack of a clear disciplinary identity, this concept coordinated research among pale- ontologists, morphologists, and developmentally inclined evolutionary biologists. I discuss the different functions that scientific concepts can have, highlighting that instead of classifying or explaining natural phenomena, concepts such as ‘devel- opmental constraint’ and ‘evolvability’ are more important in setting explanatory agendas so as to provide intellectual coherence to scientific approaches. -
Spontaneous Generation of Life Is the Inevitable Outcome of Time, Chance, and the Right Chemical Conditions
“The origin of life appears almost a miracle, so many are the conditions which would have had to be satisfied to get it going.” –Francis Crick, co-discoverer of the DNA double helix structure1 Introduction According to evolutionary theory, all life – bacteria, plants, and people – evolved from a hypothetical first cell, which allegedly arose spontaneously from chemical substrates. This is said to have happened over 3 billion years ago. That hypothetical first cell has been called LUCA (last universal common ancestor). This first cell is assumed to be at the very base of Darwin’s hypothetical “tree of life”. It is almost universally claimed that life came from non-life (abiogenesis). Is this good science? It is almost universally claimed that spontaneous generation of life is the inevitable outcome of time, chance, and the right chemical conditions. Is this claim even remotely credible? School curricula, textbooks, educational science programs, and countless museums consistently insist there is a strong scientific case for the spontaneous origin of life. From a naturalistic evolutionary perspective, it should not be surprising that spontaneous generation is assumed to be feasible, as it is essential to the evolutionary story. We can’t have Darwin’s “tree of life” without the trunk, which emerged from the primordial seed of that first cell. We are continuously told stories that sound like plausible scenarios for how simple inorganic molecules might have come together to give rise to the first living cell. However, upon careful examination, we find that the stories being told are not only extremely speculative – they are rationally indefensible. -
Activities of The
activities of the Inhalt Contents Seite Page 2 1 Jahresrückblick und Struktur des KLI Review 2010 and Structure of the KLI 6 2 Projekte Projects 2.1 Bewerbungen / Applications 2.2 Junior Gastwissenschaftler / Junior Visiting Fellows 2.3 Postdoktoranden-Stipendien / Postdoctoral Fellowships 2.4 Senior Stipendiaten / Senior Fellows 2.5 Austausch-Stipendium / Exchange Felllowship 2.6 Gastwissenschaftler / Visiting Scientists 32 3 Wissenschaftliche Veranstaltungen Meetings and Lectures 3.1 Altenberg Workshops 3.2 Symposia 3.3 Rupert Riedl Lecture 3.4 Mittagsdiskussionen / Brown Bag Discussions 50 4 Publikationen Publications 4.1 Vienna Series in Theoretical Biology 4.2 Sammelbände und Bücher / Edited Volumes and Books 4.3 Fachartikel / Professional Papers 4.4 Artikel im Druck / Papers in Press 4.5 Zeitschrift Biological Theory / Journal 4.6 Vorträge und Kongressbeiträge / Scientific Presentations 70 5 Weitere Aktivitäten Further Activities 5.1 EASPLS Graduate Meeting 5.2 Zusätzliche Förderungen Jahresrückblick und Struktur des KLI Review 2010 and Structure of the KLI 61 Through its in-house activities and freshly conceived workshops and seminar series the KLI has uniquely provided a context for rethinking major questions in developmental, cognitive, and evolutionary biology. Stuart Newman, New York Medical College Jahresrückblick und Struktur des KLI Review 2010 and Structure of the KLI 1.1 Jahresrückblick 2010 The Year in Review Der weltweit zu beobachtende Wandel der akademischen Institutionen hat in 3 den letzten Jahren auch Österreich voll erfasst. Das Gespenst der „Nützlichkeit“ geht um. Teils erzwungen, teils in vorauseilendem bürokratischen Eifer bemessen die Universitäten ihre eigenen Leistungen immer mehr nach ökonomistischen Managementkriterien. Die eigentlichen Aufgaben der akademischen Einrichtun- gen – Erkennen, Verstehen, Analyse, Wissen, Kritik, Diskurs, Bildung – die funda- mental auf intellektueller Unabhängigkeit beruhen, werden unter dem Gewicht sogenannter Effizienzkriterien zunehmend zurückgedrängt. -
Evolution & Development
DOI: 10.1111/ede.12315 RESEARCH Developmental structuring of phenotypic variation: A case study with a cellular automata model of ontogeny Wim Hordijk1 | Lee Altenberg2 1Konrad Lorenz Institute for Evolution and Cognition Research, Klosterneuburg, Abstract Austria Developmental mechanisms not only produce an organismal phenotype, but 2University of Hawai‘iatMānoa, they also structure the way genetic variation maps to phenotypic variation. ‘ Honolulu, Hawai i Here, we revisit a computational model for the evolution of ontogeny based on Correspondence cellular automata, in which evolution regularly discovered two alternative Wim Hordijk, Konrad Lorenz Institute for mechanisms for achieving a selected phenotype, one showing high modularity, Evolution and Cognition Research, the other showing morphological integration. We measure a primary variational Martinstrasse 12, 3400 Klosterneuburg, Austria. property of the systems, their distribution of fitness effects of mutation. We find Email: [email protected] that the modular ontogeny shows the evolution of mutational robustness and ontogenic simplification, while the integrated ontogeny does not. We discuss the wider use of this methodology on other computational models of development as well as real organisms. 1 | INTRODUCTION summarize, “almost anything can be changed if it shows phenotypic variation” and “combinations of traits, even The idea that phenotypic variation could ever be those unfavorably correlated, can be changed”). Once the “unbiased” is a historical artifact coming from two main premises of this “pan‐variationism” are accepted, pans- sources: First were the early characterizations of quanti- electionism is the natural conclusion—in other words, if tative genetic variation for single traits or small numbers variation is diffusing in every phenotypic direction, the of traits. -
Against Biopoetics
Louisiana State University LSU Digital Commons LSU Doctoral Dissertations Graduate School 2004 Against biopoetics: on the use and misuse of the concept of evolution in contemporary literary theory Bradley Bankston Louisiana State University and Agricultural and Mechanical College Follow this and additional works at: https://digitalcommons.lsu.edu/gradschool_dissertations Part of the English Language and Literature Commons Recommended Citation Bankston, Bradley, "Against biopoetics: on the use and misuse of the concept of evolution in contemporary literary theory" (2004). LSU Doctoral Dissertations. 1703. https://digitalcommons.lsu.edu/gradschool_dissertations/1703 This Dissertation is brought to you for free and open access by the Graduate School at LSU Digital Commons. It has been accepted for inclusion in LSU Doctoral Dissertations by an authorized graduate school editor of LSU Digital Commons. For more information, please [email protected]. AGAINST BIOPOETICS: ON THE USE AND MISUSE OF THE CONCEPT OF EVOLUTION IN CONTEMPORARY LITERARY THEORY A Dissertation Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Department of English By Bradley Bankston B.A., New College, 1990 M.A., Louisiana State University, 1999 May 2004 Table of Contents Abstract................................................iii Introduction..............................................1 Part I: Evolutionary Psychology -
Evolutionary Morphology, Innovation, and the Synthesis of Evolutionary and Developmental Biology
Biology and Philosophy 18: 309–345, 2003. © 2003 Kluwer Academic Publishers. Printed in the Netherlands. Evolutionary Morphology, Innovation, and the Synthesis of Evolutionary and Developmental Biology ALAN C. LOVE Department of History and Philosophy of Science University of Pittsburgh CL 1017 Pittsburgh, PA 15260 U.S.A. E-mail: [email protected] Abstract. One foundational question in contemporary biology is how to ‘rejoin’ evolution and development. The emerging research program (evolutionary developmental biology or ‘evo- devo’) requires a meshing of disciplines, concepts, and explanations that have been developed largely in independence over the past century. In the attempt to comprehend the present separation between evolution and development much attention has been paid to the split between genetics and embryology in the early part of the 20th century with its codification in the exclusion of embryology from the Modern Synthesis. This encourages a characterization of evolutionary developmental biology as the marriage of evolutionary theory and embryology via developmental genetics. But there remains a largely untold story about the significance of morphology and comparative anatomy (also minimized in the Modern Synthesis). Functional and evolutionary morphology are critical for understanding the development of a concept central to evolutionary developmental biology, evolutionary innovation. Highlighting the discipline of morphology and the concepts of innovation and novelty provides an alternative way of conceptualizing the ‘evo’ and the ‘devo’ to be synthesized. Key words: comparative anatomy, developmental genetics, embryology, evolutionary developmental biology, innovation, morphology, novelty, synthesis, typology 1. Introduction and methodology ... problems concerned with the orderly development of the individual are unrelated to those of the evolution of organisms through time .. -
Macroevolutionary Freezing and the Janusian Nature of Evolvability: Is the Evolution (Of Profound Biological Novelty) Going to End?
Biosemiotics https://doi.org/10.1007/s12304-018-9326-y ORIGINAL PAPER Macroevolutionary Freezing and the Janusian Nature of Evolvability: Is the Evolution (of Profound Biological Novelty) Going to End? Jan Toman1 & Jaroslav Flegr1 Received: 30 September 2017 /Accepted: 9 May 2018 # Springer Science+Business Media B.V., part of Springer Nature 2018 Abstract In a macroevolutionary timescale, evolvability itself evolves. Lineages are sorted based on their ability to generate adaptive novelties, which leads to the optimi- zation of their genotype-phenotype map. The system of translation of genetic or epigenetic changes to the phenotype may reach significant horizontal and vertical complexity, and may even exhibit certain aspects of learning behaviour. This continu- ously evolving semiotic system probably enables the origin of complex yet functional and internally compatible adaptations. However, it also has a second, Bdarker^,side.As was pointed out by several authors, the same process gradually reduces the probability of the origination of significant evolutionary novelties. In a similar way to the evolution of societies, teachings, or languages, in which the growing number of internal linkages gradually solidifies their overall structure and the structure or interpretation of their constitutive elements, the evolutionary potential of lineages decreases during biological evolution. Possible adaptations become limited to small Bperipheral^ modifications. According to the Frozen Evolution theory, some of the proximate causes of this Bmacroevolutionary freezing^ are more pronounced or present exclusively in sexual lineages. Sorting based on the highest (remaining) evolvability probably leads to the establishment of certain structural features of complex organisms, e.g. the modular character of their development and morphology. -
Meyer, Stephen C
DNA BY DESIGN: AN INFERENCE TO THE BEST EXPLANATION FOR THE ORIGIN OF BIOLOGICAL INFORMATION STEPHEN C. MEYER INTRODUCTION n the second chapter of Philosophy and Biology,Elliott Sober warns historians I and philosophers of biology against the danger of anachronism. In particular, he notes that many contemporary evolutionary biologists regard the design hypothe- sis as inherently untestable and, therefore, unscientific in principle, simply because it no longer commands scientific assent. He notes that while logically unbeatable versions of the design hypothesis have been formulated (involving, for example, a “trickster God” who creates a world that appears undesigned), design hypotheses in general need not assume an untestable character. A design hypothesis could, he argues, be formulated as a fully scientific “inference to the best explanation.” He notes that scientists often evaluate the explanatory power of a “hypothesis by test- ing it against one or more competing hypotheses.”1 On these grounds, he notes that William Paley’s version of the design hypothesis was manifestly testable, but was rejected precisely because it could not explain the relevant evidence of then con- temporary biology as well as the fully naturalistic theory of Charles Darwin. Sober then casts his lot with the neo-Darwinian explanation on evidential rather than methodological grounds. But the possibility remains, he argues, that there is some other version of the design hypothesis that both disagrees with the hypothesis of evolution and also is a more likely explanation of what we observe. No one, to my knowledge, has developed such a version of the design hypothesis. But this does not mean that no one ever will.2 This paper will develop a design hypothesis, not as an explanation for the origin of species, but as an explanation for the origin of the information required to make a living system in the first place. -
Against Biopoetics: on the Use and Misuse of the Concept of Evolution in Contemporary Literary Theory
AGAINST BIOPOETICS: ON THE USE AND MISUSE OF THE CONCEPT OF EVOLUTION IN CONTEMPORARY LITERARY THEORY A Dissertation Submitted to the Graduate Faculty of the Louisiana State University and Agricultural and Mechanical College in partial fulfillment of the requirements for the degree of Doctor of Philosophy in The Department of English By Bradley Bankston B.A., New College, 1990 M.A., Louisiana State University, 1999 May 2004 Table of Contents Abstract................................................iii Introduction..............................................1 Part I: Evolutionary Psychology and Literary Theory......11 The Model...........................................11 The Critique........................................25 Evolutionary Psychology and Literary Theme..........56 Evolutionary Psychology and Literary Form...........77 Part 2: Evolutionary Progress and Literary Theory.......114 Biological Progress................................114 Complexity.........................................130 Self-Organization..................................149 Frederick Turner: Beauty and Evolution.............154 Alexander Argyros: Self-Organization, Complexity, and Literary Theory................................179 Conclusion..............................................215 Works Cited.............................................219 Vita....................................................230 ii Abstract This dissertation is a critical assessment of “biopoetics”: a new literary theory that attempts to import ideas from evolutionary science -
Canalization and Robustness - Evolutionary Biology - Oxford Bibliog
Canalization and Robustness - Evolutionary Biology - Oxford Bibliog... http://www.oxfordbibliographies.com/view/document/obo-978019994... Canalization and Robustness Thomas Flatt, Günter Wagner LAST MODIFIED: 27 JUNE 2018 DOI: 10.1093/OBO/9780199941728-0109 Introduction Canalization describes the phenomenon whereby particular genotypes exhibit reduced phenotypic sensitivity or variation (i.e., increased robustness) in response to mutations and/or to environmental changes relative to other genotypes. Canalization is a variational property of genotypes: it implies a reduced potential or propensity of the phenotype, produced by this genotype, to vary in response to genetic or environmental change. The terms “canalization,” “robustness” and “buffering” are typically used interchangeably; today, “robustness” is perhaps more commonly used than “canalization.” The concept of canalization was first introduced by Conrad Hal Waddington in the 1940s; around the same time, Ivan Ivanovich Schmalhausen came up with essentially the same concept (see Books and Early History of the Canalization Concept). Their main conjecture was the existence of a special kind of stabilizing selection, so-called canalizing selection, which favors genotypes that deviate least from the trait optimum (e.g., the fitness optimum), by selecting for genetic mechanisms that suppress phenotypic variation caused by mutations (genetic canalization) or by environmental perturbations or changes (environmental canalization). The concept of canalization is closely related to the phenomenon of genetic assimilation, that is, the idea that previously hidden, cryptic genetic variants can become phenotypically expressed following an environmental or genetic perturbation and increase in frequency by selection. General Overviews Early experimental evidence for the existence of canalization and genetic assimilation is reviewed in depth by Scharloo 1991, the first comprehensive review paper in the field. -
Evo Devo.Pdf
FROM EMBRYOLOGY TO EVO-DEVO Dibner Institute Studies in the History of Science and Technology George Smith, general editor Jed Z. Buchwald and I. Bernard Cohen, editors, Isaac Newton’s Natural Philosophy Jed Z. Buchwald and Andrew Warwick, editors, Histories of the Electron: The Birth of Microphysics Geoffrey Cantor and Sally Shuttleworth, editors, Science Serialized: Representations of the Sciences in Nineteenth-Century Periodicals Michael Friedman and Alfred Nordmann, editors, The Kantian Legacy in Nineteenth-Century Science Anthony Grafton and Nancy Siraisi, editors, Natural Particulars: Nature and the Disciplines in Renaissance Europe J. P. Hogendijk and A. I. Sabra, editors, The Enterprise of Science in Islam: New Perspectives Frederic L. Holmes and Trevor H. Levere, editors, Instruments and Experimentation in the History of Chemistry Agatha C. Hughes and Thomas P. Hughes, editors, Systems, Experts, and Computers: The Systems Approach in Management and Engineering, World War II and After Manfred D. Laubichler and Jane Maienschein, editors, From Embryology to Evo-Devo: A History of Developmental Evolution Brett D. Steele and Tamera Dorland, editors, The Heirs of Archimedes: Science and the Art of War Through the Age of Enlightenment N. L. Swerdlow, editor, Ancient Astronomy and Celestial Divination FROM EMBRYOLOGY TO EVO-DEVO: A HISTORY OF DEVELOPMENTAL EVOLUTION edited by Manfred D. Laubichler and Jane Maienschein The MIT Press Cambridge, Massachusetts London, England © 2007 Massachusetts Institute of Technology All rights reserved. No part of this book may be reproduced in any form by any electronic or mechanical means (including photocopying, recording, or information storage and retrieval) without permission in writing from the publisher. -
Science and Religion: a Philosophical Analysis Course Number: Phi 81.1
Science and Religion: A Philosophical Analysis Course Number: Phi 81.1 Institution: St. John's University Instructor: Marie George Course Outline and Reading List (subject to revision): I. INTRODUCTION -Students will be asked to write out their views on the relation of religion and science. -Instructor will present various positions taken by scientists. Readings: Einstein, "About Religion" Aristotle on the Virtue of Religion Suggested reading: Cosmos, Bios, Theos. II. THE SCIENTIFIC METHOD AND ITS SCOPE: AN OVERVIEW A. General considerations regarding method Readings: Aristotle: Nicomachean Ethics 1098a28-b5, 1094b24; De Caelo 306a; Physics 193b33; Parts of Animals, Bk. I, c. 1; Metaphysics, Bk. II, c. 3. B. The scientific method as developed and used in Physics (the hypothetical deductive method) 1. the scientific observation 2. laws; statistical laws 3. hypotheses and theories Readings: 3 handouts C. The scientific method and biology Reading: Handout Suggested reading: Arthur Peacocke, God and the New Biology, cc. 1-4. D. Science, Natural Philosophy, and Metaphysics: a comparison of method and objects of study Readings: Handout Excerpts from Aquinas’s commentary on Boethius De Trinitate, qq. 5 & 6. Aristotle, Metaphysics, 993b10. E. Science and Theology: Readings: Summa Theologiae, I.1, articles 2, 7, 8. (Theology as science) Augustine (as quoted in Leo XIII, “Providentissimus Deus,” 23-25 and Pius XII, “Divino Afflante Spiritu”, 7). Thomas Aquinas, Summa Theologiae, I, 70.1 ad 3; Summa Contra Gentiles, Bk. II, art. 4. John Paul II, “Letter of 1988 to Rev. George V. Coyne, S.J., Director of the Vatican Observatory”. (excerpts) John Paul II, “Address to the Pontifical Academy of Science,” 10-31-92.